Publications

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helicobacter pylori-associated gastritis and gastric carcinoma in beijing.a retrospective study was performed on 500 consecutive gastric biopsies obtained from patients with a diagnosis of gastritis and gastric carcinoma. overall, helicobacter pylori was detected in 336 cases (67.2%); it was seen in 82.4% of patients with duodenal ulcer, 80.1% of patients with gastric ulcer, 76.1% of patients with chronic atrophic gastritis, 60.3% of patients with chronic superficial gastritis, and 32.1% of patients with gastric carcinoma. the gastric epithelium colonized by helicobac ...19938189377
[the prevalence and mechanism of helicobacter pylori resistance to clarithromycin in beijing].(1) to determine the prevalence of helicobacter pylori strains resistant to clarithromycin in peking. (2) to determine the genetic mutation in relation to clarithromycin resistance.200111930609
helicobacter pylori infection and gastric cancer: evidence from a retrospective cohort study and nested case-control study in china.to explore the association between helicobacter pylori (hp) infection and risk of gastric cancer in china.200212439934
regional variation among vaca alleles of helicobacter pylori in china.allelic variation among helicobacter pylori vaca occurs in the signal and middle region of the gene. the aim of the study was to investigate alleleic variation of vaca among h. pylori strains from three regional areas of china and the relationship between vaca alleles and pud. dna extracted from 88 clinical isolates of h. pylori was analyzed by type-specific pcr and reverse hybridization line probe assay (lipa) to determine the genotype of vaca and presence of caga. in 87 isolates, all of the va ...200312734231
helicobacter pylori infection, mucosal atrophy and intestinal metaplasia in asian populations: a comparative study in age-, gender- and endoscopic diagnosis-matched subjects.it is known that the incidence and mortality rate of gastric cancer is high among japanese and chinese populations, but extremely low in thai and vietnamese populations. the aim of this study was to investigate the prevalence of helicobacter pylori infection and the differences in the glandular atrophy and intestinal metaplasia scores in stomach specimens of asian adult subjects of different races.200312603614
[seroepidemiology study on helicobacter pylori (caga, vaca) infection of elderly people in beijing].to assess the prevalence rate of helicobacter pylori (h. pylori) in blood serum, its affecting factors and isoforms (caga,vaca )infection in the elderly people in beijing.200516471219
[the epidemiology of helicobacter pylori resistance to antibiotics in beijing].to investigate the prevalence of helicobacter pylori (h. pylori) resistance to metronidazole, clarithromycin and amoxicillin in beijing.200516324315
[distribution of caga 3' region, icea, vaca and hp0519 on helicobacter pylori isolated from china].this study was aimed to characterize the helicobacter pylori strains isolated from different geographic regions in china and different ethnic groups in yunnan province in terms of caga, icea, vaca and hp0519 genes which were proposed to be related to the pathogenesis.200617152512
[epidemiology of helicobacter pylori infection in shandong and beijing areas.].to study the current prevalence and recent epidemiological changes of helicobacter pylori (h. pylori) infection among children and adults residing in regions with high (muping, shandong) and low (yanqing, beijing) incidence of gastric cancer in china.200920193516
recent changes in the prevalence of helicobacter pylori infection among children and adults in high- or low-incidence regions of gastric cancer in china.the prevalence of helicobacter pylori (h. pylori) infection varies by geographic locations. studies indicate that the infection rate of h. pylori was previously high in china but that rates had been declining worldwide over recent decades. the aims of our study were: (1) to determine the current prevalence of h. pylori infection among children and adults residing in areas with high (muping county, shandong) and low (yanqing county, beijing) incidences of gastric cancer in china, and (2) to compa ...200919781321
core genome haplotype diversity and vaca allelic heterogeneity of chinese helicobacter pylori strains.the human gastric pathogen, helicobacter pylori, has co-evolved with its host and established itself in the human stomach possibly millions of years ago. therefore, the diversity of this bacterium is important in its clinical manifestations. our aim has been to evaluate the genetic diversity of 40 h. pylori clinical isolates from four different parts of china. the methods of multi-locus sequence typing and vaca allele genotyping were used to assess their genetic diversity. to discriminate mlst, ...200919452214
prevalence of helicobacter pylori infection and identification of risk factors in rural and urban beijing, china.the prevalence of helicobacter pylori is higher in developing countries such as china. the aim of this study was to investigate the prevalence of h. pylori in one rural and one urban region of beijing, china.200919298340
distribution of gyra mutations in fluoroquinolone-resistant helicobacter pylori strains.to investigate the resistance of helicobacter pylori (h. pylori) to ciprofloxacin (cip), levofloxacin (lvx) and moxifloxacin (mox) in the beijing area and to elucidate the resistance mechanisms.201020458765
the evolution of helicobacter pylori antibiotics resistance over 10 years in beijing, china.to evaluate helicobacter pylori antibiotics resistance evolution from 2000 to 2009 to amoxicillin, clarithromycin, metronidazole, tetracycline, levofloxacin and moxifloxacin in beijing, china.201021083752
primary antibiotic resistance of helicobacter pylori isolated from beijing children.the antimicrobials resistance of helicobacter pylori (h. pylori) was able to sharply decline the eradication rate of h. pylori both in adults and children, but there are limited studies about the primary antibiotic resistance and the related gene mutations, specifically in china.201121923681
[a comparison of proteomic analysis of helicobacter pylori in patients with gastritis and gastric cancer between areas of high and low incidence of gastric cancer].to identify the differentially expressed proteins of helicobacter pylori (hp) in patients with gastritis and gastric cancer from areas of high and low incidence of gastric cancer by 2-dimensional electrophoresis (2-de), and to discuss the role of bacterial factor in pathogenesis.201122178828
[a cross-sectional survey of crab intolerance positive rate and its determinants in healthy medical examination population in beijing].to explore the positive rate of crab intolerance and its related factors in a healthy physical examination population in beijing, china.201222944268
seroepidemiology of helicobacter pylori infection in elderly people in the beijing region, china.to investigate seroepidemiology of caga(+) and vaca(+) strains of helicobacter pylori (h. pylori) in an elderly population in beijing and to determine risk factors for seropositivity.201424707148
primary antibiotic resistance of helicobacter pylori strains isolated from patients with dyspeptic symptoms in beijing: a prospective serial study.to determine the resistance patterns of helicobacter pylori (h. pylori) strains isolated from patients in beijing and monitor the change of antibiotic resistance over time.201525759550
prevalence of coinfection with gastric non-helicobacter pylori helicobacter (nhph) species in helicobacter pylori-infected patients suffering from gastric disease in beijing, china.the helicobacter heilmannii sensu lato (h. heilmannii s.l.) group consists of long, spiral-shaped bacteria naturally colonizing the stomach of animals. moreover, bacteria belonging to this group have been observed in 0.2-6% of human gastric biopsy specimens, and associations have been made with the development of chronic gastritis, peptic ulceration, and gastric malt lymphoma in humans.201525510739
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