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emergence of nalidixic acid resistance in shigella sonnei isolated from patients having acute diarrheal disease: report from eastern province of saudi arabia.during the 5 years of the study period (october 1999-october 2003), 110 strains of shigella were isolated from fecal samples of patients having acute diarrheal diseases. shigella sonnei phase 1 was the most prevalent (88/110, 80.0%) serotype. resistance to nalidixic acid was not encountered from 1999-2002. nalidixic acid resistance was observed in 6/13 (46.1%) of the s. sonnei phase 1 strains isolated from april-august 2003. minimum inhibitory concentration to nalidixic acid among these strains ...200415218222
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