Publications

multiyear prospective study of intestinal parasitism in a cohort of peace corps volunteers in guatemala.	we conducted a prospective, longitudinal study in a cohort of 36 peace corps volunteers (pcvs) in guatemala to study the incidence and natural history of intestinal parasitic infections during the pcvs' >2-year overseas stay. pcvs collected stool specimens at least monthly and when ill with gastrointestinal symptoms. of the 1,168 specimens tested, 453 (38.8%) were positive for at least one parasite and 48 (4.1%) were positive for a pathogenic parasite. a median interval of 187 days (range, 14 to ...	2001	11136744
prevalence of infection with waterborne pathogens: a seroepidemiologic study in children 6-36 months old in san juan sacatepequez, guatemala.	water and sanitation interventions in developing countries have historically been difficult to evaluate. we conducted a seroepidemiologic study with the following goals: 1) to determine the feasibility of using antibody markers as indicators of waterborne pathogen infection in the evaluation of water and sanitation intervention projects; 2) to characterize the epidemiology of waterborne diarrheal infections in rural guatemala, and 3) to measure the age-specific prevalence of antibodies to waterb ...	2004	14971703
confirmed detection of cyclospora cayetanesis, encephalitozoon intestinalis and cryptosporidium parvum in water used for drinking.	human enteropathogenic microsporidia (hem), cryptosporidium parvum, cyclospora cayetanesis, and giardia lamblia are associated with gastrointestinal disease in humans. to date, the mode of transmission and environmental occurrence of hem (encephalitozoon intestinalis and enterocytozoon bieneusi) and cyclospora cayetanesis have not been fully elucidated due to lack of sensitive and specific environmental screening methods. the present study was undertaken with recently developed methods, to scree ...	2003	15384722
a study of risk factors associated with the prevalence of cryptosporidium in villages around lake atitlan, guatemala.	cryptosporidium parvum is an endemic, zoonotic coccidian parasitosis that is highly prevalent in third-world countries where waterborne fecal contamination of food and drink or person-to-person contact with oocysts are the most common methods of transmission of the enteric protozoan. this type of transmission of the parasite made the villages around lake atitlan, guatemala a unique site to compare environmental risk factors with the level of cryptosporidium infections in the local residents. the ...	2004	15565263
comparing serologic response against enteric pathogens with reported diarrhea to assess the impact of improved household drinking water quality.	we evaluated enteric infection serology as an alternative outcome measure to diarrhea prevalence in a randomized controlled trial of household-based drinking water treatment; 492 households were randomly assigned to 5 household-based water treatment interventions or control. individuals were followed weekly over 52 weeks to measure diarrhea prevalence. study subjects of age <or= 6 months and < 24 months had blood drawn at entry and exit from the study or age cohort. serologic assays for cryptosp ...	2007	17620645
molecular insights for giardia, cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system in guatemala.	abstract. we molecularly characterized samples with giardia, cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system for diarrhea in santa rosa, guatemala. the dna sequence analysis determined the presence of giardia assemblages a (n = 7) and b (n = 12) and, cryptosporidium hominis (n = 2) and cryptosporidium parvum (n = 2), suggestive of different transmission cycles. all 41 samples with soil-transmitted helminths did not have the β-tubulin mutation described f ...	2011	22144459