Publications

detection of the tick-borne encephalitis virus (tbev) in ticks in several federal "länder" of germany by means of the polymerase chain reaction (pcr)--characterization of the virus.	the aim of the present study was to analyse the current epidemiological situation with respect to tbe in the new federal "länder" of germany and in saarland through detection of the tbev genome in unengorged ticks using an rt-pcr technique. 22,273 ticks (ixodes ricinus) were collected in the five new "länder" (and some in bavaria and baden-württemberg) and divided into 294 pools. it was possible to detect tbev rna in six pools of ticks from mecklenburg western-pomerania [4], brandenburg [1], thu ...	1996	8923058
prevalence of granulocytic ehrlichiae in ixodes ricinus ticks in middle germany (thuringia) detected by pcr and sequencing of a 16s ribosomal dna fragment.	a total of 305 ixodes ricinus ticks (243 nymphs and 62 adults) were collected from three different regions of thuringia in middle germany which are known to be endemic for borrelia burgdorferi. our aim was to investigate the carrier rate of ticks for granulocytic ehrlichia species. the presence of ehrlichial 16s ribosomal dna was investigated by polymerase chain reaction. using primers specific for the ehrlichia phagocytophila group pcr fragments of 151 bp and 943 bp, respectively, were produced ...	2002	12076817
prevalence of four species of borrelia burgdorferi sensu lato and coinfection with anaplasma phagocytophila in ixodes ricinus ticks in central germany.	a total of 305 ixodes ricinus ticks collected from three areas of thuringia in central germany were investigated for infection with borrelia burgdorferi sensu lato species and anaplasma phagocytophila. overall, 11.1% were infected with borrelia burgdorferi and 2.3% with anaplasma phagocytophila. adult ticks showed a significantly higher rate of infection with both borreliae and anaplasma phagocytophila. borrelia garinii (55.9%) was detected most frequently, followed by borrelia burgdorferi sensu ...	2003	12783276
tick-borne encephalitis (tbe) in germany--epidemiological data, development of risk areas and virus prevalence in field-collected ticks and in ticks removed from humans.	in germany, 100-300 autochthonous clinical tbe cases have been recorded annually. there are high-risk areas in bavaria and baden-wuerttemberg and ongoing low-risk areas in hesse, thuringia, and the rhineland-palatinate and single cases in saxony. in order to be able to evaluate the epidemiological changes described here, it must be mentioned that a new definition of tbe risk areas was introduced on the district level in 1998 in germany and in 2001 with the new infection protection act (infektion ...	2004	15146987
role of birds in thuringia, germany, in the natural cycle of borrelia burgdorferi sensu lato, the lyme disease spirochaete.	three hundred and twenty-two birds belonging to 35 species were live-captured in reifenstein, middle germany, from march to october 2004, to investigate their role as hosts of borrelia burgdorferi sensu lato and its vector ticks. a total of 141 ixodes ricinus ticks collected from 53 birds belonging to eight species was investigated for the prevalence of b. burgdorferi by a pcr-rflp analysis of the ospa gene. three of these bird species, the blackbird (turdus merula), the song thrush (t. philomel ...	2006	16530003
detection of rickettsia spp. and anaplasma phagocytophilum in ixodes ricinus ticks in a region of middle germany (thuringia).	rickettsia spp. and anaplasma spp. are regarded as potentially emerging tick-borne pathogens, but so far data on prevalence rates in questing ticks and reports on human diseases in several parts of europe are rarely available. in this study, 430 nymphs and 570 adult ixodes (i.) ricinus ticks were collected from a frequently visited forest region of thuringia (zeitzgrund, near stadtroda) in 2006 (n=506) and 2007 (n=494). individual ticks were investigated for a part of the citrate synthase gene ( ...	2010	21771511
coexistence of borrelia spp. and babesia spp. in ixodes ricinus ticks in middle germany.	altogether, 430 nymphs and 570 adult ixodes ricinus ticks were collected in 2006 (n = 506) and 2007 (n = 494) from a forest area in middle germany (thuringia). single ticks were investigated by polymerase chain reaction and restriction fragment length polymorphism or sequencing for borrelia spp. (ospa gene) and babesia spp. (18s rrna gene). overall, 27.0% (270/1000) were infected with borrelia species. out of these, borrelia garinii was detected most frequently (133/270)-especially, ospa serotyp ...	2010	20420533
tick-borne encephalitis (tbe) virus prevalence and virus genome characterization in field-collected ticks (ixodes ricinus) from risk, non-risk and former risk areas of tbe, and in ticks removed from humans in germany.	tick-borne encephalitis (tbe) is recognized as the most important viral tick-borne zoonosis in 27 countries in europe. in this study, ticks were collected in germany from two non-risk areas in the states of saxony-anhalt and mecklenburg-western pomerania, where several single human tbe cases have occurred in recent years. ticks were also collected from a region in thuringia, known to be a former risk area for tbe virus (tbev), where numerous human cases were reported between 1960 and 1975. detec ...	2010	19906276
diversity and coexistence of tick-borne pathogens in central germany.	in total, 1000 ixodes ricinus l. ticks were collected from a small recreational forest area in central germany (thuringia) and investigated for the presence of borrelia spp., babesia spp., anaplasma spp., rickettsia spp., coxiella burnetii, and francisella tularensis. overall, 43.6% of the ticks were infected with at least one pathogen. in 8.4% of ticks double infections were detected, and 1.6% harbored more than two pathogens. in this study, we present data on the coexistence of established and ...	2011	21661327