Publications

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[etiopathogenetic approach to the treatment of viral-bacterial pneumonias].the efficacy of aerosols of leukocytal interferon used in complex with antibacterial and other medicamentous agents was studied during influenza epidemic in 1975 due to port-chalmers virus of influenza a with increased numbers of viral-bacterial pneumonia. the viral-sta-phylococcal etiology of the infection was confirmed in 80 per cent of the cases under stationary conditions. various microorganism and most often staph aureus were isolated in addition to the viruses from the patient's sputum and ...1976828482
[interlaboratory quality control of the agar diffusion test for determining sensitivity of microorganisms to antibiotics]. 19846199568
[use of genetic and molecular characteristics of r plasmids as an epidemiological marker in an outbreak of hospital infection].antibiotic sensitivity of 38 strains of enteric bacteria, such as serratia marcescens klebsiella pneumoniae and others and ps. aeruginosa isolated during an outbreak of meningitis in a premature infant resuscitation department was studied. it was shown that all the isolates were multiple resistant, most frequently to 7 antibiotics. all the resistance markers were transferred on conjugation, segregation of some markers being observed. investigation of the plasmid composition of the clinical strai ...19846422842
[antibiotic resistance of hospital strains of pseudomonas aeruginosa in resuscitation and intensive therapy units]. 19853933417
[the assessment of the toxigenicity of clinical strains of pseudomonas aeruginosa by an immunoenzyme method using nitrocellulose filters].the enzyme immunoassay (eia) on nitrocellulose filters was adapted for the detection of exotoxin a in 104 p. aeruginosa strains isolated from patients and the environment in surgical wards in hospitals of moscow and alma-ata. the method was shown to be highly sensitive: it permitted the detection of 5.ng of p. aeruginosa exotoxin a. the screening of 104 p. aeruginosa clinical strains by means of eia on nitrocellulose filters revealed that these strains exotoxin a in 88.5% of cases.19902151496
[microflora of clinical specimens from patients of the anesthesiological and resuscitation units]. 19911909056
antibodies against the common polysaccharide and protein protective antigens of pseudomonas aeruginosa in normal blood donors.screening of normal plasma obtained from 172 blood donors from the helsinki area and from 46 blood donors from the moscow area was performed in order to reveal 'natural' antibodies to the common polysaccharide (rhamnan) and protein antigens of p. aeruginosa. antibodies were detected by elisa. among blood donors from the helsinki area high titres of antibodies to the protein antigens were detected in 42 active blood donors (24.4%) and very high titres in nine (5.3%) highly-active blood donors, wh ...19911812933
[characteristics of fauces microflora in children treated in intensive care units].characteristic features of fauces aerobic microflora in children treated in intensive care units (icu) were analysed. for comparison fauces microflora in children outpatients and in children patients from general surgical units was investigated. a retrospective analysis of all the smears without exception for 2 years (a total of 2120) revealed a direct dependence of the changes in the fauces microflora composition on the patient condition and the antibiotic load. it was shown that the fauces ind ...19989777101
[hospital infections caused by pseudomonas aeruginosa. significance in intensive therapy].the significance of p. aeruginosa as an agent of hospital infections in intensive care departments is determined by high prevalence of this microorganism, its natural and acquired resistance to antibiotics of various groups, and severity of the infection it induces. the resistance of p. aeruginosa to antibiotics is different in different regions. among the strains isolated in moscow in intensive care wards for newborns 9% were resistant to meropenem, 10% to amicacine, 15% to imipramine, 16% to c ...199910458038
[the structure and antibiotic sensitivity of the causative agents of community-acquired infectious diseases of bacterial origin in children].four hundred and forty pediatric patients at the age of 7 days to 15 years with various infections admitted to the hospital within a month were examined. the biological material was inoculated to blood agar on the first days of the patient admittance to the hospital and after the growth the organisms were isolated and identified. antibiotic susceptibility of the isolates was assayed with the disk diffusion method. 479 strains in all were tested. the most frequent cases requiring hospitalization ...200010768061
[opportunistic microorganisms in urinary tract diseases].the microflora of clinical material (urine, urethral discharge and smear, vaginal discharge and smear, feces in colonic dysbacteriosis) from patients with urinary tract infections (uti) in the moscow region was studied. escherichia coli and staphylococcus epidermidis have been found to be the most common agents isolated from the urine of uti patients. pseudomonas aeruginosa and other staphylococcal species and enterococci account for a smaller proportion of infections. high- (e. coli and s. epid ...200111338508
[resistance epidemiology of gramnegative nonfermenting pathogens of nosocomial infections in intensive care units and surgical departments].etiological structure, patterns and antibiotic resistance mechanisms of gramnegative nonfermenting pathogens of nosocomial infections isolated from patients in intensive care units and surgical departments were investigated. one hundred thirty one clinical isolates, including 86 (65.6%) isolates of pseudomonas aeruginosa and 45 (34.4%) isolates of acinetobacter baumannii were tested. carbapenems and cefoperazone/sulbactam showed the highest activity against the tested isolates. eleven carbapenem ...200618035729
[study on prevalence and molecular mechanisms of antibacterial resistance in gram-negative pathogens of nosocomial infections in hospitals of moscow and perm'].a significant increase of resistance in out-of-hospital and hospital pathogens to antimicrobials is being lately observed all over the world, including the russian federation. within 2005-2007 clinical strains of potential producers of extended spectrum beta-lactamases were isolated in diverse medical centres. the isolates suspected to produce extended spectrum beta-lactamases by the criteria of clsi (clinical and laboratory standards institute, usa) were included into the test with the polymera ...200718986019
[antimicrobial susceptibility and molecular mechanisms of resistance to beta-lactams of gram-negative microorganisms--causative agents of nosocomial infections].profiles and mechanisms of resistance to beta-lactam antibiotics of isolates of gram-negative microorganisms, which are causative agents of infections in intensive care unit of hospital surgery department, were studied. two hundred and ten clinical isolates were studied: pseudomonas aeruginosa--86 strains (40.9%), acinetobacter baummanii--45 strains (21.4%), klebsiella pneumoniae--52 strains (24.8%), escherichia coli--23 strains (11%), enterobacter spp.--4 strains (1.9%). profiles of antibiotic ...200718038541
[mono- and associated microflora during wound infection in patients with burns].to study etiologic role of microorganisms during wound infection and elucidation of their populations interaction in patientswith burns.200920099390
[genotypic features of pseudomonas aeruginosa strains circulating in surgical hospital].to study genetic diversity of pseudomonas aeruginosa strains circulating in intensive care unit (icu), to determine the source of these strains and duration of circulation of epidemically-significant clone in the hospital.200920063790
[rate and level of contamination of potentially dangerous water supply facilities in moscow region by legionella pneumophila].to assess rate and level of contamination by legionella pneumophila of cooling water systems in industrial facilities as well as hot water supply systems of administrative buildings in moscow region.201021381372
[microbial population of lower respiratory tract in children from different age groups with cystic fibrosis].to study microflora of lower respiratory tract of children from different age groups with cystic fibrosis during follow-up for determination of its variability and possible sources of infectious complications.201020218338
[the prevalence of metallo-β-lactamases and efflux-mediated mechanisms in carbapenem nonsusceptible nosocomial pseudomonas aeruginosa isolated in moscow in 2012-2015].pseudomonas aeruginosa, the major nosocomial opportunistic pathogen, is an important cause of infectious morbidity and mortality among immunocompromised patients.201527093795
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