Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| ivth annual meeting on basic research in chagas disease (biology of trypanosoma cruzi). minas gerais, brazil, 5--7 november 1977. abstracts. | 1978 | 31667 | |
| the threat of reintroduction of natural transmission of chagas' disease in bambuí, minas gerais state, brazil, due to panstrongylus megistus. | in the epidemiological surveillance program in the county of bambuí, minas gerais, between august 1986 and december 1988, 154 panstrongylus megistus were captured by the local population in both peridomicile and intradomicile environments. fifteen (9.8%) of the p. megistus harboured trypanosoma cruzi. precipitin tests showed that the most frequent triatomine blood meal sources were birds, but other sources were dogs, men and cats. the isoenzyme characterization of 13 t. cruzi strains showed that ... | 1992 | 1308572 |
| the importance of the opossum (didelphis albiventris) as a reservoir for trypanosoma cruzi in bambuí, minas gerais state. | in a survey realized on the sylvatic and peridomestic environments at bambuí county, minas gerais state, 44 (37.9%) out of 116 opossums (didelphis albiventris) captured were found to be naturally infected with trypanosoma cruzi. one hundred and forty three parasite samples were obtained from 43 infected opossums using simultaneously hemoculture, xenodiagnosis (triatoma infestans, panstrongylus megistus and rhodnius neglectus) and examination of anal glands contents. the parasite samples were cha ... | 1991 | 1842405 |
| evaluation of the xenodiagnosis of chronic chagas patients infected ten years or over in an area where transmission has been interrupted--iguatama and pains, west minas gerais state, brazil. | to evaluate the results of xenodiagnosis in chronic chagas patients infected for ten years or over in an area where transmission has been stemmed as well as the performance of these tests applied one or more times to determine the presence of the parasite in serum-positive patients for trypanosoma cruzi infection, 570 xenodiagnosis were performed in 246 patients by exposing each patient to 40 triatoma infestans nymphs of 3rd/4th stage once, twice or three times, at 30 days intervals. the 570 xen ... | 1991 | 1842429 |
| [natural infection of the anal glands of the opossum (didelphis albiventris) by trypanosoma cruzi in the municipality of bambuí--mg, brazil]. | out of 87 opossums, didelphis albiventris, captured in the bambuí area (minas gerais state), 32 (36.7%) were found infected by trypanosoma cruzi; the rates varied according to whether the specimens originated from sylvan, rural peridomiciliar or urban surroundings, being 34.9, 81.8 and 7.7 respectively. from 20 of the infected opossums the anal glands were repeatedly examined and found positive in only one (5%) specimen (ga 9), with 7 positive examinations out of 17 performed through an 18-month ... | 1989 | 2108308 |
| [positive serology of syphilis, toxoplasmosis and chagas' disease in pregnant women in their first visit to health centers in a metropolitan area, brazil]. | the diagnosis of some infectious diseases contracted during pregnancy is very important, as these diseases can be transmitted to the fetus. four hundred and eighty-one pregnant women were studied, of an average 24.5 years of age (from 14 to 46), during their first prenatal visit to the state of s. paulo's health care centres in the subdistrict of paz (butantan), city of s. paulo, brazil, between april and october, 1988. classified by trimester of pregnancy, 230 patients (47.8%) fell into the fir ... | 1990 | 2129293 |
| [development of chronic human chagas cardiopathy in the hinterland of the paraíba state, brazil, in a 4.5 year period]. | two sectional studies about chronic chagas' disease were performed at a 4.5 year interval, involving the urban populations of agua branca, catingueira, emas, imaculada, mãe d'agua, olho d'agua, piancó and são josé de caiana counties in the sertão region of the state of paraíba. the evolution of heart disease was evaluated in 125 matched pairs of chronic chagasic and non-chagasic patients of the same sex, age and county of origin through electrocardiograms (ecg) at rest. the following evaluation ... | 1990 | 2131491 |
| seroprevalence of trypanosoma cruzi infection among unskilled urban workers in central brazil. | a cross-sectional survey of the prevalence of trypanosoma cruzi infection was carried out among urban unskilled workers in an endemic area in central brazil as part of a study to assess the health impact of chagas disease and to identify risk factors for the evolution of cardiopathy. blood samples from 5425 male and female workers, aged 15-61 years, from 5 public institutions, were screened by indirect immunofluorescence, enzyme-linked immunosorbent assay and indirect haemagglutination for antib ... | 1989 | 2515628 |
| [morbidity of chagas disease. cross sectional study in an endemic area, virgem da lapa, minas gerais]. | 2016 | 3120255 | |
| [prevalence of cholelithiasis in necropsies of patients with chronic chagas' disease in the mining triangle--correlation with megaesophagus, megacolon and cardiac insufficiency]. | retrospective analysis of the diagnosis of 2.517 autopsies performed in the western region of the state of minas gerais, brazil, showed that cholelithiasis has significant association with megaesophagus and megacolon but not with chagas' disease (when considered in all of its anatomo-clinic presentations) or with heart failure due to chronic chagasic cardiopathy. possible explanations to these findings are discussed and the scanty pertinent literature is commented. | 2007 | 3936459 |
| [morbidity in chagas' disease. iii. longitudinal study of 6 years, in virgem da lapa, mg, brazil]. | in a clinical, radiological and electrocardiographical, follow-up study of the "case control" type performed in virgem da lapa, minas gerais state, brazil, 124 chagasic patients were followed during six years. the results of the patients, the majority in the indeterminate form, did not register any change, in 32.2% there was a progress in the disease and in 5.6% the electrocardiogram returned to normal. these results when compared to that achieved by the control group, composed of pairs of non c ... | 2014 | 3937014 |
| [morbidity in chagas' disease. iv. longitudinal study of 10 years in pains and iguatama, minas gerais, brazil]. | an evolutive study of the "case-control" type was carried out in an endemic area of chagas' disease in minas gerais state, brazil, using two cross-section evaluations with an interval of ten years between them (1974-1984). patients were paired for sex and age. in the first cross-section study 264 pairs one with a positive serology and the other with a negative serology for t. cruzi antibodies were included. in the second evaluation, ten years later, 235 patients among those with previous positiv ... | 2006 | 3937015 |
| [chagas' disease in minas gerais: current status and perspectives]. | 1985 | 3939610 | |
| [chagas' disease prevalence in children from five municipalities of south-west region of minas gerais, brazil]. | 1985 | 3939869 | |
| the identification of two main-groups of trypanosoma cruzi stocks from brazil by their isoenzyme patterns of isoelectrofocusing. | the isoelectrofocusing of seven enzymes was studied using extracts of 40 brazilian stocks of t. cruzi culture forms. four enzymes showed intraspecific variation in enzyme profiles and were selected for characterization of t. cruzi. these enzymes are: nonspecific esterase (e.c.3.1.1), phosphoglucomutase (e.c. 2.7.5.1), glucose-6-phosphate dehydrogenase (e.c. 1.1.1.49) and glucosephosphate isomerase (e.c. 5.3.1.9). the parasite stocks were isolated from endemic areas in the states: rio grande do s ... | 1982 | 6215750 |
| [occurrence and biology of rhodnius neglectus lent, 1954 in palm trees of suburban areas of belo horizonte, minas gerais]. | eighty-one "macaubeiras" palm-trees (acrocomia sclerocarpa) from the periphery of belo horizonte city were cut down and dissected between april 1979 and july 1980. 60.5% of the trees were positive for r. neglectus and 463 specimens of this insect were collected, providing a mean rate of 9,45 individuals for positive palm-trees. r. neglectus seems to present a single annual generation in this region, but evidence was obtained that two generations may occur. its spawn period is related to the hot ... | 1984 | 6443015 |
| housing and the control of vectors of human chagas' disease in the state of minas gerais, brazil. | 1982 | 6810979 | |
| use of a simplified polymerase chain reaction procedure to detect trypanosoma cruzi in blood samples from chronic chagasic patients in a rural endemic area. | the feasibility of using dna amplification by the polymerase chain reaction (pcr) for specific detection of trypanosoma cruzi in human blood specimens was investigated. one hundred blood samples were collected in an endemic area of minas gerais, brazil. they were submitted to dna extraction and pcr amplification with kinetoplast dna-specific primers using a simplified boiling procedure that linearized most minicircle molecules without the aid of chemical reagents. samples that gave negative resu ... | 1994 | 7810810 |
| evaluation of the chagas' disease vector control program in minas gerais, brazil, with special reference to triatoma sordida. | as of 1979, data gathered by the chagas' disease control program (cdcp) in the brazilian state of minas gerais indicated that triatoma infestans was the chagas' disease vector most commonly found in and around human dwellings. a decade later, however, this picture had changed, presumably as a result of control efforts; few specimens of t. infestans were collected; and triatoma sordida had become the most commonly collected vector insect. the aim of the work reported here was to assess the effect ... | 1994 | 7951364 |
| a quasi-experimental epidemiological model for evaluating public health programmes: efficacy of a chagas disease control programme in brazil. | reported is the assessment of a model to evaluate the efficacy of public health programmes, using the example of the chagas disease control programme in the state of minas gerais, brazil. the reduction in trypanosoma cruzi infection rates in areas where interventions had been carried out for 5 years and 10 years, respectively, were compared with those where there had been no intervention (controls). a random sample of 470 households was selected and blood samples were collected from the 2354 inh ... | 1994 | 7955020 |
| [the clinical, social and occupational aspects of chagas disease in an endemic area under the control of the state of minas gerais, brazil]. | among 301 construction workers examined in bambuí, brasil, 11.6% presented positive serology for american trypanosomiasis, with a prevalence of 5.0% in the age group 17-29 years, 13.8% in the 30-39 and 39.4% in the 40-57. electrocardiographic disturbances were detected in 31.3% of the seropositive and in 7.1% of the seronegative individuals, with a significant difference in the age group 40-57 years. cardiac enlargement and esophagopathy were detected respectively in 8.6% and 8.6% of the positiv ... | 1993 | 8128077 |
| [a longitudinal electrocardiogram study of chagas' disease from the acute phase]. | several studies have been done to analyse the relationship between the characteristics of the electrocardiogram (ecg) and mortality in the several stages of the disease, using different methods like multiple case and longitudinal studies. we analysed the ecg from the acute stage up to twenty years of follow-up (+/- 9 years) in 42 patients with chagas' disease to determine their evolution and it's value like an index for therapeutic evaluation. the 42 patients (18 female, 24 males) were originall ... | 2006 | 8146391 |
| inter-relation of sylvatic and domestic transmission of trypanosoma cruzi in areas with and without domestic vectorial transmission in minas gerais, brazil. | during the period 1980-1986, we captured triatomine bugs and mammalian reservoir hosts from sylvatic and domestic situations in different municipalities of the state of minas gerais. trypanosoma cruzi was isolated from captured bugs, mammals and patients. after cultivation in lit medium, the electrophoretic enzyme profiles were determined. we obtained a total of 32 parasite isolates from regions with active domestic transmission, and 24 isolates from areas under control. for the first areas the ... | 1995 | 8551947 |
| [hospital morbidity for chagas disease in brazil]. | the aim of this research was to describe the delivery and evolution of chagas disease with in-patients in brazil during the last decade. it also attempted to discuss the limits and possibilities of internal hospitalization authorization (aih) as a source of epidemiologist information. from 1984 to 1993, the number of in-patients diagnosed with "tripanossomiase" was about 1,700 yearly, declining in absolute numbers during the entire historic series. the majority concentration of in-patients occur ... | 2006 | 8713602 |
| attempts to improve xenodiagnosis: comparative test of sensibility using rhodnius neglectus, panstrongylus megistus, triatoma vitticeps and triatoma infestans in endemic areas of brazil. | from june 1984 to july 1992, 392 xenodiagnostic tests were applied on 264 patients with chronic chagas disease from brazilian endemic areas of virgem da lapa and coronel murta, situated in the jequitinhonha valley, in the state of minas gerais. the susceptibilities of rhodnius neglectus, panstrongylus megistus, triatoma vitticeps and triatoma infestans were compared. most of the time 20 nymphs (fourth instar) of each species were applied to 161 women and 103 men aged between 5 and 83 years of ag ... | 1997 | 9302418 |
| isoenzymes detect variation in populations of triatoma brasiliensis (hemiptera: reduviidae: triatominae). | triatoma brasiliensis is one of the most important vectors of chagas disease in the semiarid zone of the northeast of brazil. intraspecific morphological and behavioural variation has been reported for different populations. results for four distinct populations using eight isoenzymes are reported here. the literature describes three subspecies: t. brasiliensis brasiliensis neiva, 1911; t. brasiliensis melanica neiva & lent, 1941 and t. brasiliensis macromelasoma galvão, 1956. these subspecies d ... | 1997 | 9361737 |
| [control of triatoma sordida in rural peri-domestic environment of the porteirinha municipality, minas gerais, brazil]. | triatoma sordida, a predominantly peridomestic species, is currently the triatomine species most frequently collected in brazil. to evaluate the effectiveness of control activities against this species, a survey to determine infestation rates was carried out in october 1993 in 12 rural localities in the municipality of porteirinha, state of minas gerais, brazil. in the survey, 772 t. sordida were captured, of which 3.6% were infected with trypanosoma cruzi. of the 406 dwellings investigated, 34. ... | 1998 | 9503959 |
| molecular epidemiology of american trypanosomiasis in brazil based on dimorphisms of rrna and mini-exon gene sequences. | american trypanosomiasis is transmitted in nature via a sylvatic cycle, where trypanosoma cruzi interacts with wild triatomines and mammalian reservoirs, or via a domestic cycle where the parasite comes into contact with humans through domiciliated triatomines. the pool of t. cruzi isolates consists of sub-populations presenting a broad genetic diversity. in contrast to the heterogeneity suggested by isoenzyme analysis, pcr amplification of sequences from the 24s alpha rrna gene and from the non ... | 1998 | 9504338 |
| ecotopes, natural infection and trophic resources of triatoma brasiliensis (hemiptera, reduviidae, triatominae). | triatoma brasiliensis is considered as one of the most important chagas disease vectors in the northeastern brazil. this species presents chromatic variations which led to descriptions of subspecies, synonymized by lent and wygodzinsky (1979). in order to broaden bionomic knowledge of these distinct colour patterns of t. brasiliensis, captures were performed at different sites, where the chromatic patterns were described: caicó, rio grande do norte (t. brasiliensis brasiliensis neiva, 1911), it ... | 1998 | 9698835 |
| ["me? i'm just here, part of the world". a field experience on endemic disease control in cansanção, minas gerais, brazil]. | this free-style article reports an experience with chagas' disease control involving community participation in the jequitinhonha valley (minas gerais, brazil) implemented during the 1980s and recently reevaluated. as an action-based participant research project, it was supported by the socioeconomic tdr committee (who/wb/undp) in the area of popular education. the main objective was to investigate the meaning of chagas' disease from the community's perspective, seeking alternative control measu ... | 1998 | 9700234 |
| [chagas disease in virgem da lapa, minas gerais, brazil. iv. clinical and epidemiological aspects of left ventricular aneurism]. | the study aimed at the evaluation of the clinical and epidemiological characteristics of the aneurysm found in the left ventricle in chronic chagas' disease patients. three hundred, eighty eight people (298 chagasic patients and 90 randomly selected healthy individuals) were submitted to echocardiography. the ventricular function was assessed in the m mode by calculating the fraction of ejection, and in the bidimensional mode by analyzing he global systolic function. segmental contractility was ... | 1998 | 9789444 |
| chagas disease control programme in brazil: a study of the effectiveness of 13 years of intervention. | reported is an evaluation of 13 years of intervention by the chagas disease control programme in an endemic area (montalvania) in the state of minas gerais, brazil. the design used was an epidemiological panel study. the reduction of trypanosoma cruzi infection rates was estimated from data collected on three separate occasions: a serological survey in 1975-80, a quasi-experimental study in 1987, and the present investigation. a random sample of 156 households was selected and blood samples were ... | 1998 | 9803589 |
| presence of human immunodeficiency virus (hiv) and t-lymphotropic virus type i and ii (htlv-i/ii) in a haemophiliac population in belo horizonte, brazil, and correlation with additional serological results. | the aim of this study was to determine the prevalence of human immunodeficiency virus type 1 (hiv-1) and human t lymphotropic virus types i and ii (htlv-i/ii) infections in 226 haemophiliac patients treated at fundação hemominas in belo horizonte, minas gerais state, brazil, and to verify association with other serological results. patients positive for htlv-i/ii had also a neurological, haematological and ophthalmological evaluation. fundação hemominas offers comprehensive care for all haemophi ... | 1998 | 9873865 |
| anti-trypanosoma cruzi antibodies in the inhabitants of urban and rural areas of abadia dos dourados, state of minas gerais, brazil. | 1998 | 10030079 | |
| characterization of rhodnius neglectus from two regions of brazil using isoenzymes, genitalia morphology and morphometry. | among the triatomines considered as secondary in the epidemiology of chagas disease, rhodnius neglectus is frequently captured in artificial ecotopes, especially peridomiciliary ones, rarely producing colonies indoors. nevertheless, the presence of breeding colonies in houses was unquestionably demonstrated in some areas of the state of goiás, brazil. previous isoenzyme comparisons of this species with morphologically close triatomines, such as r. prolixus, r. robustus or r. nasutus, did not pro ... | 1999 | 10224521 |
| prevalence of hiv-1/2, htlv-i/ii, hepatitis b virus (hbv), hepatitis c virus (hcv), treponema pallidum and trypanosoma cruzi among prison inmates at manhuaçu, minas gerais state, brazil. | the purpose of this study was to determine the seroprevalence of human immunodeficiency virus (hiv-(1/2)), human t-cell lymphotropic virus (htlv-i/ii), hepatitis b virus (hbv), hepatitis c virus (hcv), treponema pallidum and trypanosoma cruzi among 63 male prisoners in manhuaçu, minas gerais, brazil and to compare this with data from eligible blood donors. the positive results were as follows: 11/63 (17.5%) for hbv, 5/63 (7.4%) for syphilis, 4/63 (6.3%) for hcv, 3/63 (4.8%) for chagas' disease, ... | 2000 | 10881115 |
| the bambuí health and ageing study (bhas): methodological approach and preliminary results of a population-based cohort study of the elderly in brazil. | a cohort study has been designed to identify predictors of adverse health events in the elderly. the methodology of the study and preliminary descriptive results are presented. | 2000 | 10881147 |
| comparative developmental and susceptibility to insecticide of bolivian and brazilian populations of triatoma infestans. | the triatomine bug triatoma infestans probably originated in bolivia and dispersed passively over wide areas of south america, where it is the principal vector of trypanosoma cruzi. in the region of its probable origin this species shows colonization in two different ecotopes, so that it may be encountered in sylvatic as well as in artificial habitats. the sylvatic colonization pattern is not observed in the rest of its range, where t. infestans is exclusive to man-made habitats. the objective o ... | 2000 | 11080780 |
| [epidemiological surveillance in the chagas disease control program in minas gerais state, brazil (1984-1998)]. | this paper describes the surveillance phase of the chagas disease control program in minas gerais state. surveillance was conducted by the county health services with community participation in the planning, decision-making, and maintenance processes and is intended to be sustainable in the context of brazil's unified national health system (sus). | 2000 | 11119329 |
| nested case-control study in a serological survey to evaluate the effectiveness of a chagas disease control programme in brazil. | to identify risk factors associated with trypanosoma cruzi infections in areas under surveillance in the state of minas gerais, brazil. | 2001 | 11417036 |
| [chagas' disease in lassance, minas gerais state: clinical-epidemiological re-evaluation ninety years after the discovery by carlos chagas]. | the history and present situation of chagas' disease in lassance (the county where carlos chagas discovered american trypanosomiasis) were studied through a historical analysis and clinical and epidemiological research performed from 1999 to 2001. lassance was an important focus of chagas' disease from carlos chagas up until the 1980's, because of intensive infestation in dwellings by panstrongylus megistus and triatoma infestans, two important species which were efficiently controlled in the la ... | 2002 | 12011926 |
| progressive chagas' cardiomyopathy is associated with low selenium levels. | selenium (se) deficiency is linked with some cardiomyopathies. its status was determined in 170 patients with chronic chagas' disease from 2 brazilian regions (rio de janeiro and belo horizonte), clinically stratified into groups as follows: indeterminate or asymptomatic (ind); cardiac asymptomatic (carda); cardiac symptomatic with moderate to severe heart dysfunction (cardb); and healthy adults (ha), used for comparison. in most ha, se levels were normal, excluding an overall se deficiency. se ... | 2002 | 12224578 |
| seroprevalence of helicobacter pylori infection in chronic chagasic patients, and in the rural and urban population from uberlândia, minas gerais, brazil. | as patients with chronic chagas disease exhibit morphological and functional changes of the stomach (hypomotility and hypochlorhydria), malnutrition, immunological deficiency and high prevalence of peptic disease associated to helicobacter pylori infection, the purpose of this study was to evaluate if the prevalence of h. pylori infection in chronic chagasic is higher than in non-chagasic individuals in the urban and rural population from uberlândia, mg, brazil. serological determination of igg ... | 2002 | 12436163 |
| biological screening of annonaceous brazilian medicinal plants using artemia salina (brine shrimp test). | eighteen different extracts from five annona species collected in minas gerais state, brazil, were submitted to the brine shrimp lethality test in order to detect potential sources of novel cytotoxic, antitumor, pesticidal and anti-trypanosoma cruzi compounds. all of the annonaceous species tested showed good larvicidal activity as compared to a reference compounds and literature data. | 2003 | 12725579 |
| obesity and underweight among brazilian elderly: the bambuí health and aging study. | the coexistence of obesity (body mass index, bmi > or = 30kg/m ) and underweight (bmi <= 20kg/m ) and related factors were investigated among all residents aged 60+ years in bambu , minas gerais state, using multinomial logistic regression. 1,451 (85.5%) of the town's elderly participated. mean bmi was 25.0 (sd = 4.9kg/m ) and was higher for women and decreased with age. prevalence of obesity was 12.5% and was positively associated with female gender, family income, hypertension, and diabetes an ... | 2003 | 12764476 |
| socioeconomic position and health in a population of brazilian elderly: the bambuí health and aging study (bhas). | despite the vast scientific literature on the social determinants of health, there is still a debate on the extent to which this relationship remains in old age. the objective of this study was to examine the association between socioeconomic circumstances and health among older adults in a small town in brazil. | 2003 | 12880519 |
| the epidemiologic importance of triatoma brasiliensis as a chagas disease vector in brazil: a revision of domiciliary captures during 1993-1999. | to clarify the epidemiologic importance of triatoma brasiliensis, the most important chagas disease vector in the northeastern of brazil, capture data related to this species, its distribution, capture index, and percentages of natural infection by trypanosoma cruzi were examined in 12 different brazilian states. the brazilian national health foundation collected these data from 1993 to 1999, a period during which a total of 1,591,280 triatomines (21 species) were captured in domiciles within th ... | 2003 | 12937751 |
| [chagas' disease in school children. i. results of a survey of joão pessôa pupils in belo horizonte, minas gerais, brazil]. | 1953 | 13060927 | |
| [chagas' disease in children admitted to hospitals in belo horizonte, minas gerais, brazil]. | 1953 | 13060943 | |
| biomedical research and public health in brazil: the case of chagas' disease (1909-50). | this article analyses two periods in the history of scientific and social legitimization of american trypanosomiasis or chagas' disease, discovered in brazil in 1909 by carlos chagas, physician and researcher at the instituto oswaldo cruz. initially we focus on research during chagas' lifetime, a phase during which the basic statements of the disease were formulated; then, the action in the 1940s and 1950s by the researchers of the centro de estudos e profilaxia de moléstia de chagas, located in ... | 2003 | 14598820 |
| chagas disease in a community in southeast brazil. i. a serologic follow-up study on a vector controlled area. | the prevalence of trypanosoma cruzi infection was evaluated in berilo, minas gerais (mg), brazil, from january to july 1997. a serological survey using the indirect immunofluorescence test (ift) in dried blood collected on filter-paper was performed in a sample of 2,261 individuals. the overall prevalence rate of t. cruzi infection was 18%, and reached 50% in individuals older than 30 years from rural areas. the percentage of seropositivity was 0.17% among individuals younger than 10 years old, ... | 2003 | 14743667 |
| [the impact of the extensive chemical control of triatoma infestans on the incidence of acute cases and the prevalence of human chagas disease. the example of montalvânia, minas gerais state]. | from the emergency of acute cases of chagas disease in montalvânia, minas gerais, brazil, with the implementation of triatomine chemical control, the disappearing of these cases and the immediate reduction of incidence of the infection in the municipality are verified. the evolution of the dispersion and control of triatoma infestans in montalvânia and the evolution of the serology in general population during the last thirty years are showed. | 2003 | 15049113 |
| on the possibility of autochthonous chagas disease in roraima, amazon region, brazil, 2000-2001. | chagas disease has been almost entirely eradicated from the arid zones in central and northeastern brazil where rare or no autochthonous cases have been reported. however, in the last 10 years the disease has increasingly been registered in the amazon region. aiming to investigate the possibility of the occurrence of autochthonous cycle of chagas disease in roraima, triatomine collections, vectorial susceptibility studies (this one to be shown elsewhere), parasitological and serological analyses ... | 2005 | 15729474 |
| [entomological surveillance for chagas disease in the mid-western region of minas gerais state, brazil, from 2000 to 2003]. | in minas gerais state, brazil, after the elimination of triatoma infestans by the brazilian chagas disease control program, some triatomine species, such as panstrongylus megistus, have merited the attention of entomological surveillance authorities. after the decentralization of the brazilian health system, certain administrative and operational difficulties have been observed in some municipalities (counties). this study aims to evaluate entomological surveillance for chagas disease in the 54 ... | 2005 | 15868046 |
| [about the use of "maria" bio-sensors in the activities of epidemiological surveillance against chagas' disease in the north of minas gerais state]. | eight hundred and sixty six bio-sensors for the passive detection of triatomine bugs, were tried in intra-domiciles of thirteen municipalities of an endemic area of triatoma sordida in the north of minas gerais state, brazil. this species is nowadays the most captured in brazil and mainly in the above region. the sensors were examined every three months, corresponding to four times in the first seven municipalities (six hundred and forty two sensors, with a maximum positivity of 0.5%) and two ti ... | 2005 | 16172750 |
| random amplified polymorphic dna profiles of trypanosoma cruzi isolates from chagasic patients with different clinical forms. | the genetic variability of 61 trypanosoma cruzi isolates from 47 chronic chagasic patients of minas gerais state was analyzed by random amplified polymorphic dna polymerase chain reaction (rapd-pcr) using m13-40, lambdagt11-f, and l15996 primers. cluster analysis by unweighted pair group method analysis was applied to rapd profiles, and cluster analysis used to verify a possible correlation among different clinical forms of the disease from these patients. the t. cruzi isolates showed distinct g ... | 2006 | 16416119 |
| [congenital transmission of trypanosoma cruzi in brazil: estimation of prevalence based on preliminary data of national serological surveys in children under 5 years old and other sources]. | a prevalence estimation of congenital transmission in brazil is performed, based on several sources of recent data. from a serological survey conducted now in brazil, with children below 5 years old, preliminary data from the state of minas gerais only 19/9,556 children did have antibodies against trypanosoma cruzi. all 19 mothers were infected, but only one child persisted with antibodies on a second blood collection, hence diagnosed as congenital. the other were just passive transference of ma ... | 2005 | 16482808 |
| [clinical and epidemiological profile of patients with chagas disease at the university hospital in maringá, paraná, brazil]. | this paper describes the clinical and epidemiological profile of patients with chagas disease treated in outpatient and inpatient departments at the maringá university hospital (uhm) in paraná state, brazil, from may 1998 to may 2003. mean age was higher among hospitalized patients (p < 0.000). hospitalized patients were predominantly males, as opposed to inpatients who were mostly females (p = 0.0033). of the 95 patients, 60% were born in the states of minas gerais and são paulo and 25.3% in pa ... | 2006 | 16680355 |
| seroprevalence of chagas disease in schoolchildren from two municipalities of jequitinhonha valley, minas gerais, brazil; six years following the onset of epidemiological surveillance. | six years after the beginning of the epidemiological surveillance of chagas disease in berilo and josé gonçalves de minas, jequitinhonha valley, mg, brazil, a serological inquiry was performed to observe whether the transmission of this endemy was occurring in this area. a randomized sample of 1,412 children seven to 14 years old, was screened. six asymptomatic children were found to be positive, leading to 0.4% of prevalence. hemoculture confirmed infection in five out of the six positive cases ... | 2006 | 16699629 |
| [integral insecticide spraying followed by immediate triatomine research, as an additional strategy for the epidemiological surveillance of chagas' disease, in areas of residual persisting foci]. | the locality of altolândia (tapiraí municipality, minas gerais, brazil), frequently presents panstrongylus megistus infestation in the domiciliary environment. in order to improve epidemiological surveillance in this area, a strategy of domiciliary pyrethroid spraying with high flushing-out effect followed by immediate triatomine research, was implemented in all the existing dwellings. the main objectives were the detection and elimination of cryptic foci, thus reducing the opportunities for new ... | 2006 | 16699656 |
| the controversy on the early history of chagas disease. | recently historians of medicine have proposed three distinctive accounts of early history of chagas disease (american trypasonomiasis). according to the first the disease, described by the brazilian researcher carlos chagas in 1909, was "deconstructed" in the 1920s and disappeared for about twenty years, then was recovered in the 1940s, mainly through the epidemiological studies of emmanuel dias and his colleagues in minas gerais (brazil). according to the second chagas disease could not be "dec ... | 2005 | 16866038 |
| science, health and development: chagas disease in brazil, 1943-1962. | the present paper discusses the historical construction and legitimacy of chagas disease as a distinct nosological entity and as a public health issue in brazil. it focuses on the activities of a group of researchers from oswaldo cruz institute who worked at the centre for the study and prevention of chagas disease, located in bambuí, minas gerais. led in the 1940s and 50s by emmanuel dias, disciple of carlos chagas, the group made important contributions to the clinical characterization of chag ... | 2005 | 16866044 |
| [internal migration and distribution of chagas disease mortality, brazil, 1981-1998]. | in brazil, mortality from chagas disease occurs even in regions classified as free of vector transmission. because death rates refer to residents, and considering that a huge migratory movement has occurred inside the country, this study was intended to quantify the contribution of brazilian internal migration to overall mortality from chagas disease, from 1981 to 1998. if the paho southern cone initiative actually achieved its objectives, one could expect declining death rates and increasing ag ... | 2006 | 16951885 |
| domiciliation of triatoma pseudomaculata (corrêa e espínola 1964) in the jequitinhonha valley, state of minas gerais. | impact of the vector control program was evaluated eight years after implantation of epidemiological surveillance for chagas disease in berilo, a municipality in the jequitinhonha valley of the brazilian state of minas gerais. in all 5,242 domiciliary units (96% of the total) were inspected and 10 found to be infested by the triatomine bug triatoma pseudomaculata. triatomines were found associated with bats inside one house and in the peridomiciles of the other nine. none of the 111 triatoma pse ... | 2007 | 17876457 |
| [chagas disease epidemiological surveillance in a decentralized program: evaluation of practice and knowledge among municipal health agents in an endemic region of minas gerais state, brazil]. | this study aimed to evaluate the epidemiological surveillance of chagas disease in the central-western region of minas gerais state, brazil, based on knowledge and practice among municipal health agents working in the chagas disease control program. thirty-five municipalities (counties) were visited, with meetings and application of a questionnaire on knowledge, practice, and difficulties in conducting the surveillance work. twenty-six agents were on temporary (annual) contracts, and only two ha ... | 2007 | 17891303 |
| [survey on chagas disease in the hospital da santa casa de misericórdia de belo horizonte (minas gerais, brasil)]. | 2012 | 18208022 | |
| pre-columbian chagas disease in brazil: trypanosoma cruzi i in the archaeological remains of a human in peruaçu valley, minas gerais, brazil. | we evaluated the presence and distribution of trypanosoma cruzi dna in a mummy presenting with megacolon that was dated as approximately 560 +/- 40 years old. the mummy was from the peruaçu valley in the state of minas gerais, brazil. all samples were positive for t. cruzi minicircle dna, demonstrating the presence and broad dissemination of the parasite in this body. from one sample, a mini-exon gene fragment was recovered and characterized by sequencing and was found to belong to the t. cruzi ... | 2008 | 18797771 |
| [evaluation of the chagas disease control program and presence of panstrongylus megistus in central-western minas gerais state, brazil]. | the brazilian national chagas disease control program (pcdch) is currently in the epidemiological surveillance phase and poses one of the principal challenges for maintaining and improving surveillance. with the decentralization of health actions, leading to the transfer of responsibilities over the control of endemic diseases to the state and municipal governments, some municipalities have faced difficulties in implementing the program, since they lack experience in controlling this disease. th ... | 2009 | 19347217 |
| probing population dynamics of trypanosoma cruzi during progression of the chronic phase in chagasic patients. | our research aimed to characterize the genetic profiles of 102 trypanosoma cruzi isolates recently obtained from 44 chronic chagasic patients from different regions of the states of minas gerais and goiás in brazil. at least two isolates were obtained from each patient at different times in order to study the parasite population dynamics during disease progression in the chronic phase. the isolates were characterized molecularly by genotyping the 3' region of the 24s alpha rrna, the mitochondria ... | 2009 | 19357212 |
| [evaluation of knowledge and practices related to chagas disease and its vectors among adults and children in an endemic region in minas gerais state, brazil]. | despite the success of the chagas disease control program (pccd) in brazil, some endemic areas have experienced difficulty in maintaining the program's activities, especially after the health system's decentralization, since the sustainability of control measures for chagas disease and vectors is known to depend on information and community participation. this study aimed to analyze knowledge and practices related to vectors and chagas disease in bambuí, minas gerais state, brasil. the populatio ... | 2009 | 19649411 |
| head morphometry and isoenzymatic profile of two triatoma infestans klůg, 1834 (hemiptera, reduviidae) populations. | the triatomine bug triatoma infestans was probably originated in bolivia and dispersed passively over large areas of south america, where it is the major vector of trypanosoma cruzi. in its probable origin area this species shows two different patterns of behaviour, being found both in sylvatic and human related habitats. such behaviour is not observed in other areas of its distribution, where it is exclusive to human related habitats. the main objective of the present study was to evaluate head ... | 2011 | 19653989 |
| [how health activities view man and how man rethinks them: an anthropological analysis of chagas disease control]. | this anthropological study addresses the cultural perceptions of a group of residents in the city of bambuí, minas gerais state, brazil, in relation to experience with chagas disease and the impact of health measures on social life. the ethnographic study was based on open interviews, seeking to identify individual perceptions among 35 inhabitants of bambuí (with and without chagas disease) living in the region since the 1940s, when chagas disease control activities were launched. within a broad ... | 2009 | 19750382 |
| [epidemiological analysis of patients coinfected with chagas disease and cysticercosis]. | among inhabitants of endemic areas in the developing world, infection with the larva of taenia solium (cysticercosis) may possibly induce a state of immunosuppression in the host, thereby increasing the risk of multiple infections after exposure to other parasites, such as trypanosoma cruzi. | 2009 | 19753846 |
| carlos chagas: biographical sketch. | carlos chagas was born on 9 july 1878 in the farm "bon retiro" located close to the city of oliveira in the interior of the state of minas gerais, brazil. he started his medical studies in 1897 at the school of medicine of rio de janeiro. in the late xix century, the works by louis pasteur and robert koch induced a change in the medical paradigm with emphasis in experimental demonstrations of the causal link between microbes and disease. during the same years in germany appeared the pathological ... | 2010 | 19895782 |
| clinical and laboratory status of patients with chronic chagas disease living in a vector-controlled area in minas gerais, brazil, before and nine years after aetiological treatment. | twenty-eight chagas disease patients (cd), 22 with the indeterminate clinical form (ind) and six with the cardiac or digestive form (card/dig), were treated with benznidazole and underwent clinical and laboratorial analysis before (ind and card/dig) and nine years after [patients after treatment (cdt), patients with the indeterminate clinical form at treatment onset (indt) and with the cardiac or digestive form at treatment onset (card/digt)] treatment. the data demonstrate that 82.1% of cdt pat ... | 2009 | 20140375 |
| entomological surveillance of chagas disease in berilo municipality, jequitinhonha valley, state of minas gerais, brazil. | this study aimed to evaluate the chagas disease control program which has operated since 1982 in the municipality of berilo in the jequitinhonha valley, minas gerais, brazil, based on evaluation of 5,242 domiciliary units (dus) and 7,807 outbuildings over an eight-year period of epidemiological surveillance implanted in 1997. a total of 391 triatomines (280 panstrongylus megistus and 111 triatoma pseudomaculata) were captured, indicating the continued predominance of the former species. however, ... | 2009 | 20209342 |
| [analysis on the food source of panstrongylus megistus (hemiptera, reduviidae, triatominae) and its present importance as a vector for trypanosoma cruzi, in the state of minas gerais]. | investigation of the food source of triatomines helps in understanding the biology of these insects, and also helps to infer their importance in transmitting trypanosoma cruzi to humans. | 2010 | 20464139 |
| [clinic and epidemiological study on chagas disease in the serra azul district of mateus leme, central-western region of the state of minas gerais, brazil]. | chagas disease remains a severe public health problem in latin america, despite control over its transmission. this study evaluated the prevalence of chagas disease in the serra azul district, in the central-western region of the state of minas gerais, through identifying electrocardiographic (ekg) abnormalities among serologically positive individuals. | 2011 | 20464149 |
| penalized likelihood and multi-objective spatial scans for the detection and inference of irregular clusters. | irregularly shaped spatial clusters are difficult to delineate. a cluster found by an algorithm often spreads through large portions of the map, impacting its geographical meaning. penalized likelihood methods for kulldorff's spatial scan statistics have been used to control the excessive freedom of the shape of clusters. penalty functions based on cluster geometry and non-connectivity have been proposed recently. another approach involves the use of a multi-objective algorithm to maximize two o ... | 2010 | 21034451 |
| [the beginning of chagas disease control (homage to dr. emmanuel dias, the pioneer of chagas disease control, in the year of his birth centenary)]. | very soon carlos chagas took into account the need of trypanosomiasis control, considering its great social impact and geographical dispersion the vector was considered the more vulnerable target and housing improvement the basic strategy to face the disease. in parallel, it was required a more clinical visibility for the disease, as an argument for its control. the first concrete tentative occurred in 1918 when souza araújo dedicating his efforts in paraná, trying housing improvement. he was fo ... | 2011 | 21584352 |
| [institutional insertion of chagas' disease control]. | after the starting of the center for studies and prophylaxis of chagas disease in 1943, with the help of oswaldo cruz foundation, in the city of bambuí, state of minas gerais, technological and methodological basis for the extensive control of the disease were conceived. a main step to achieve success was the introduction of a new insecticide (gammexane, p 530) and the demonstration of its efficacy in the vector control. a consequence of these improvements was the official inauguration of the fi ... | 2011 | 21584353 |
| [the control of vectorial transmission]. | between 1950 and 1951, the first prophylactic campaign against chagas diseases was carried on in brazil by the so existing serviço nacional de malária. the actions involving chemical vector control comprehended 74 municipalities along the rio grande valley, between the states of são paulo and minas gerais. ever since, until 1975, the activities were performed according the availability of resources, being executed with more or less regularity and coverage. at that time, chagas disease did no rep ... | 2011 | 21584358 |
| first report of panstrongylus megistus sylvatic focus in municipality of bambuí, state of minas gerais, brazil. | in 1943, the center for the study and prophylaxis of chagas disease, oswaldo cruz foundation, state of minas gerais (mg), was created in the municipality of bambuí to carry out studies related to chagas disease in the mid-western region of mg. since that time, several investigations have been conducted to determine the natural habitat of triatomines, but panstrongylus megistus colonies have never been found in this region. this paper records the first finding of a p. megistus sylvatic colony in ... | 2011 | 21739044 |
| the bambuí cohort study of aging: methodology and health profile of participants at baseline. | the cohort study was initiated in 1997 to investigate the incidence and predictors of health outcomes in an elderly population with low socio-economic level. the eligible population consisted of all 1,742 residents in bambuí, minas gerais state, brazil, aged 60 years and over (1,606 participated). during 10 years of follow-up, 641 participants died and 96 were lost, leading to 13,739 person-years of observation. the baseline health profile of participants revealed a double burden of diseases wit ... | 2011 | 21952853 |
| Infestation of Mauritia flexuosa palms by triatomines (Hemiptera: Reduviidae), vectors of Trypanosoma cruzi and Trypanosoma rangeli in the Brazilian savanna. | To determine the infestation and trypanosome infection of triatomines captured in Mauritia flexuosa palm trees across its geographic distribution in the Brazilian savanna (Cerrado), we sampled 42 localities in eight states and in the Federal District, Brazil, between July 2005 and January 2010. Overall, 2154 specimens of the species Rhodnius neglectus, Psammolestes tertius, Triatoma sordida, and Microtriatoma borbai, were collected. Among the 341 palms sampled, 182 (53.3%) were infested with R. ... | 2012 | 22037200 |
| biological behaviour in mice of trypanosoma cruzi isolates from amazonas and paraná, brazil. | the biological behaviour of 23 trypanosoma cruzi isolates in swiss mice was compared. nineteen isolates were obtained from patients in the acute phase of chagas disease (13), sylvatic reservoir hosts (didelphis marsupialis) (3), and triatomine bugs (rhodnius robustus) (3) from four regions of the state of amazonas (am). four isolates were obtained from chronic chagasic patients in the state of paraná (pr): three autochthones, and one allochthone from the state of minas gerais. only one isolate w ... | 2012 | 22406038 |
| epidemiological profile of trypanosoma cruzi-infected mothers and live birth conditions in the state of minas gerais, brazil. | the aim of this study was to assess the epidemiological characteristics of trypanosoma cruzi-infected mothers and the live birth conditions of neonates. | 2013 | 23740060 |
| [nutritional aspects associated with chronic trypanosoma cruzi (chagas 1909) infection among older adults: bambuí project]. | the aim of the study was to verify nutritional aspects associated with chronic trypanosoma cruzi infection among baseline participants from the bambuí cohort study on aging. the analysis included 84.9% (1,479) of residents of bambuí, minas gerais state, brazil, who were 60 years or older in 1997. t. cruzi infection was investigated by three serological tests, and nutritional status was assessed by anthropometric and biochemical variables. associations were evaluated by prevalence ratios and conf ... | 2013 | 23778546 |
| molecular and biological characterization of trypanosoma cruzi strains isolated from children from jequitinhonha valley, state of minas gerais, brazil. | the biological diversity of trypanosoma cruzi strains plays an important role in the clinical and epidemiological features of chagas disease. | 2013 | 23982097 |
| evidence of substantial recombination among trypanosoma cruzi ii strains from minas gerais. | due to the scarcity of evidence of sexuality in trypanosoma cruzi, the causative agent of chagas disease, it has been general accepted that the parasite reproduction is essentially clonal with infrequent genetic recombination. this assumption is mainly supported by indirect evidence, such as hardy-weinberg imbalances, linkage disequilibrium and a strong correlation between independent sets of genetic markers of t. cruzi populations. however, because the analyzed populations are usually isolated ... | 2014 | 24296011 |
| profile of the trypanosoma cruzi vector infestation in jaboticatubas, state of minas gerais, brazil. | this work aimed to analyze the triatomine infestation scenario in jaboticatubas after 30 years of the uninterrupted actions of the program of chagas disease control. | 2014 | 24474024 |
| [new data on the distribution of triatomids and their infection by schizotrypanum cruzi in the state of minas gerais, brazil]. | 1950 | 24539416 | |
| current situation and perspectives regarding human chagas disease in midwestern of the state of minas gerais, brazil. | recognising the importance of chagas disease in brazil, bambuí set up epidemiological surveillance for chagas disease in 1974 and was the first municipality to do so. to ascertain the current epidemiology of chagas disease in this municipality, 1.782 blood samples from the general population were analysed; 7.7% of samples were found to be seropositive for chagas disease. a strong positive correlation between increasing age and chagas disease was evident in both genders, with the highest prevalen ... | 2014 | 24831551 |
| evaluation of the chagas disease control program in açucena municipality, rio doce valley, state of minas gerais, brazil. | açucena municipality, rio doce valley, state of minas gerais, brazil temporarily (2001-2005) interrupted epidemiological surveillance for chagas disease. the objective of this work was to evaluate the chagas disease control program (cdcp) in açucena and to offer suggestions for improving local epidemiological surveillance. | 2014 | 24861292 |
| genetic variability and geographical diversity of the main chagas' disease vector panstrongylus megistus (hemiptera: triatominae) in brazil based on ribosomal dna intergenic sequences. | studies were made on the ribosomal dna intergenic region, comprising complete internal transcribed spacer (its)-1, 5.8s, and its-2 sequences, of populations of the triatomine panstrongylus megistus, the most important vector of chagas' disease in brazil since triatoma infestans eradication. specimens were from 26 localities of rio grande do sul, santa catarina, paraná, são paulo, minas gerais, bahia, and sergipe states. in total, 21 its-1 and 12 its-2 haplotypes were found. nucleotide difference ... | 2014 | 24897854 |
| species of the subfamily triatominae jeannel, 1919 (hemiptera: reduviidae) present in the collection of chagas disease vectors (fiocruz-colvec), state of minas gerais. | biological collections are depositories of information on different species and contribute to the knowledge, protection, conservation and maintenance of biodiversity. | 2015 | 25626652 |
| experimental benznidazole treatment of trypanosoma cruzi ii strains isolated from children of the jequitinhonha valley, minas gerais, brazil, with chagas disease. | trypanosoma cruzi strains from distinct geographic areas show differences in drug resistance and association between parasites genetic and treatment response has been observed. considering that benznidazole (bz) can reduce the parasite burden and tissues damage, even in not cured animals and individuals, the goal is to assess the drug response to bz of t. cruzi ii strains isolated from children of the jequitinhonha valley, state of minas gerais, brazil, before treatment. mice infected and treate ... | 2015 | 25742267 |
| deltamethrin toxicological profile of peridomestic triatoma sordida in the north of minas gerais, brazil. | in general, there was a large reduction in the occurrence of cases of chagas disease in the last decades in brazil. however, despite all of these efforts, there have been various reports of persistent reinfestations of t. sordida in a large part of the state of minas gerais, for reasons still little investigated. thus, this purpose of this study was to characterize the deltamethrin susceptibility profile of peridomestic t. sordida populations from north of minas gerais-brazil. | 2015 | 25952153 |
| one million electrocardiograms of primary care patients: a descriptive analysis. | in 722 cities of minas gerais (brazil), primary care patients can have their ecgs remotely interpreted by cardiologists of the telehealth network of minas gerais (tnmg), a public telehealth service. as of december 2014, more than 1.9 million ecgs were interpreted. this study analyzed the database of all ecgs performed by the tnmg on primary care patients from 2009 to 2013 (n=1,101,993). structured patient data and the results of automated ecg interpretation by the glasgow program are described. ... | 2015 | 26262012 |
| prevalence of chagas disease among blood donor candidates in triangulo mineiro, minas gerais state, brazil. | despite public health campaigns and epidemiological surveillance activities, chagas disease remains a major health problem in latin america. according to data from the world health organization, there are approximately 7-8 million people infected with trypanosoma cruzi worldwide, a large percentage of which in latin america. this study aims to examine the serological profile of blood donors in blood banks of hemominas hematology center, in the town of ituiutaba, minas gerais state, brazil. the s ... | 2015 | 27049698 |