| a vero cell derived combined vaccine against sheep pox and peste des petits ruminants for sheep. | the combined sheep pox and peste des petits ruminants (ppr) vaccine was prepared in lyophilized form containing recommended doses of both vaccine viruses. safety and immunogenicity of this combined vaccine was evaluated in sheep. sheep immunized subcutaneously with 1ml of live attenuated vaccine consisting of 10(3)tcid(50) each of sheep pox virus (spv) romanian fanar (rf) strain and peste des petits ruminants virus (pprv-sungri/96 strain) were monitored for clinical and serological responses for ... | 2009 | 19428860 |
| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |
| post-vaccination antibodies profile against peste des petits ruminants (ppr) virus in sheep and goats of punjab, pakistan. | a total of 70 sheep and 330 goats were selected randomly. all the animals were kept under same housing and management conditions. serum samples were collected from all the animals and tested for the presence of antibodies against peste des petits ruminants (ppr) virus using competitive elisa (celisa). all the animals were found negative showing percentage inhibition (pi) values <50. the animals were vaccinated against ppr with nig/75/1 strain vaccine of ppr serum samples were collected from rand ... | 2009 | 18758987 |
| [sequence analysis of the matrix protein and fusion protein genes of a field peste des petits ruminants virus strain from tibet, china]. | the nucleotide sequences of m and f genes from a field strain of peste des petits ruminants virus (pprv) ("china/tib/gej/07-30") was firstly determined. the m gene was 1 483 nucleotides in length with a single open reading frame (orf), encoding a protein of 335 amino acids. the f gene was 2411 nucleotides in length, encoding a protein of 546 amino acids. the resulting nucleotide sequence and the deduced amino acid sequences were compared with the homologous regions of other pprv isolates. the nu ... | 2010 | 20836385 |
| an outbreak of peste des petits ruminants in migratory flocks of sheep and goats in egypt in 2006. | an outbreak of peste des petits ruminants (ppr) was recorded in kalubia province, egypt in 2006, affecting a large population of migratory goats and sheep over a huge geographical area. epidemiological, clinical and laboratory investigations were performed. diseased animals showed pyrexia, erosive stomatitis, enteritis and bronchopneumonia. clinical manifestations were more severe in goats. the overall morbidity, cumulative mortality and case fatality rates were 26.1%, 10.5% and 40.2%, respectiv ... | 2010 | 21309463 |
| exotic animal diseases bulletin. peste des petits ruminants. | | 2010 | 21222301 |
| peste des petits ruminants of sheep in india. | | 1989 | 2609485 |
| evidence of peste des petits ruminants virus (pprv) infection in sindh ibex (capra aegagrus blythi) in pakistan as confirmed by detection of antigen and antibody. | an outbreak resulting in mortality in sindh ibex (capra aegagrus blythi) was investigated. there was a history of about 36 deaths (both young and adult) during the period of 1 month. disease appeared in a generalized form, affecting the respiratory and digestive systems. major lesions were respiratory distress, pustules on and in the mouth, ocular-nasal discharges, and severe diarrhea. the most significant lesion was the oculonasal discharges and diarrhea. deaths were mainly due to blindness, an ... | 2011 | 21221782 |
| economics of prophylaxis against peste des petits ruminants and gastrointestinal helminthosis in small ruminants in north cameroon. | data on reproduction and mortality were collected over one year from 5100 sheep and 13,300 goats in treated and control flocks. the treated animals received vaccination against peste des petits ruminants (ppr) and anthelmintics twice a year. productivity parameters (fecundity and mortality rates) obtained with and without prophylaxis were fitted into a benefit-cost economic analysis model and run for project lifespans varying from one to five years. at a 7% discount rate, the overall benefits fo ... | 2000 | 11147279 |
| the epidemiology of peste des petits ruminants in pakistan. | peste des petits ruminants (ppr) is an acute and highly contagious viral disease of small ruminants, which is newly emerging in pakistan. information provided by participatory disease surveillance teams was used to develop a database for ppr outbreaks in pakistan. twenty-four villages were selected throughout the country and field investigations were conducted in each village to study the dynamics of the disease. in each area, flocks with a history of ppr were identified and serological sampling ... | 2008 | 19284055 |
| differentiating pestes des petits ruminants and rinderpest viruses by a novel monoclonal antibody. | peste des petits ruminant (ppr) is an acute, febrile, viral disease of small ruminants with great economic importance. ppr and rinderpest (rp) viruses are antigenically related and need to be differentiated serologically. the use of monoclonal antibodies (mabs) in elisa for specific diagnostics and separation of ppr and rpv is important. for this purpose, six balb/c mice were immunized with inactivated antigen from the nijeria strain. fusion cloning was performed 3 months later by directly using ... | 2011 | 21707365 |
| Molecular characterization and phylogenetic study of peste des petits ruminants viruses from North central States of Nigeria. | Peste des petits ruminants is an endemic disease of sheep and goats in Nigeria and vaccination has been the method of control but sporadic outbreaks have been reported. This study was carried out to characterize PPR viruses from outbreaks in 2007 and 2009 from Kaduna and Plateau States. | 2011 | 21726444 |
| examination of epithelial tissue cytokine response to natural peste des petits ruminants virus (pprv) infection in sheep and goats by immunohistochemistry. | in this study, we aimed to evaluate expression of il-4, il-10, tnf-α, ifn-γ and inos in lingual, buccal mucosa and lung epithelial tissue using immunoperoxidase technique and to compare with the tissues of control animals. the tissues used in the study were collected from 17 pprv-affected and 5 healthy sheep and goats. in pprv positive animals, the lungs, lingual and buccal mucosa had significantly higher inos, ifn-γ and tnf-α expressions compared to control group animals. there was no significa ... | 2012 | 22127598 |
| prevalence and distribution of peste des petits ruminants virus antibodies in various districts of tanzania. | despite the widespread prevalence of infection with peste des petits ruminants virus (pprv) in goats and sheep industry in asia and sub-saharan africa, there have been few, if any, structured population-based studies examining the epidemiology of this infection in tanzania. in this study, we investigated the seroprevalence, and risk factors, of peste des petitis ruminants(ppr) in sheep and goat flocks from seven different geographical administration authorities (ngorongoro, monduli, longido, kar ... | 2009 | 19705291 |
| evidence of peste des petits ruminants in serology of sheep and goats from sindh, pakistan. | the following is the first detailed description of laboratory confirmed evidence of peste des petits ruminant virus (pprv) in 14 districts of sindh province, pakistan. sindh is the 2nd largest province of pakistan in terms of human population and livestock. livestock are the main origin of the people's livelihood. samples were collected during the surveillance programme from sheep and goats showing severe respiratory signs and mouth lesions. competitive enzyme-linked immuno-sorbant assay (celisa ... | 2010 | 21167015 |
| quantitative one-step real-time rt-pcr for the fast detection of the four genotypes of pprv. | a one-step real-time taqman rt-pcr assay (rrt-pcr) for peste des petits ruminants virus (pprv) was developed to detect the four lineages of pprv by targeting the nucleoprotein (n) gene of the virus. this new assay was compared to a conventional rt-pcr on reference strains and field materials. quantitation was performed against a standard based on a synthetic transcript of the nppr gene for which a minimum of 32 copies per reaction were detected with a corresponding c(t) value of 39. depending on ... | 2010 | 20116402 |
| Seroprevalence and sero-conversion after vaccination against Peste des Petits Ruminants in sheep and goats from Awash Fentale District, Afar, Ethiopia. | A cross-sectional epidemiological study followed by vaccination and postvaccinal serum antibody assessment against Peste des Petits Ruminants (PPR) in small ruminant population of Awash Fentale District, Afar, Ethiopia, was conducted from September 2006 to June 2007 with the aim of investigating seroprevalence and post-vaccination sero-conversion rate. A total of 1239 sera collected from sheep and goats which were not vaccinated, were screened by using nucleoprotein-based competitive enzyme-link ... | 2012 | 22088269 |
| comparative efficacy of peste des petits ruminants (ppr) vaccines. | peste des petits ruminants (ppr) is a highly contagious, economically important viral disease of sheep and goats with high morbidity and mortality rates. in order to control the disease effectively, highly sensitive diagnostic tests coupled with potent vaccines are important pre-requisites. at present, there are three live attenuated ppr vaccines available in india including sungri 96, arasur 87 and coimbatore 97. indian veterinary research institute (ivri) mukteswar developed the ppr sungri 96 ... | 2010 | 20199873 |
| dual infection of fetal and neonatal small ruminants with border disease virus and peste des petits ruminants virus (pprv): neuronal tropism of pprv as a novel finding. | dual infection of 26 fetal and neonatal small ruminants with border disease virus (bdv) and peste des petits ruminants virus (pprv) is reported. the animals included five aborted lamb fetuses, 19 neonatal lambs and two neonatal kids from flocks in regions of the black sea and the aegean region. bdv and pprv antigens were detected immunohistochemically in the brain, oral mucosa, intestine and lung of infected animals. reverse transcriptase-polymerase chain reaction was used to demonstrate pprv an ... | 2011 | 21899857 |
| a short note on peste des petits ruminants in karnataka, india. | retrospective quantitative analysis of epidemiological data on peste des petits ruminants (ppr) from the department of animal husbandry and veterinary sciences in karnataka, southern india, revealed significant information about the disease in this area. in the nine years between april 1998 and march 2007 a total of 624 outbreaks were reported in the state. with the exception of the 12-month period between april 2001 and march 2002 the disease occurred every year. the study shows clearly that in ... | 2009 | 20462160 |
| seroprevalence of peste des petits ruminants in cattle and buffaloes from southern peninsular india. | this study describes seroprevalence of peste des petits ruminants (ppr) in cattle and buffaloes carried out during the period 2009-2010 using the randomly collected serum samples from different parts of southern peninsular india. the report presents the results of ppr virus (pprv)-specific antibodies in situations where either the subclinical or inapparent or non-lethal infection was there in cattle and buffaloes. a total of 2,548 serum samples [cattle = 1,158, buffaloes = 1,001, sheep = 303 and ... | 2012 | 22105906 |
| monkey cv1 cell line expressing the sheep-goat slam protein: a highly sensitive cell line for the isolation of peste des petits ruminants virus from pathological specimens. | peste des petits ruminants (ppr) is an important economically transboundary disease of sheep and goats caused by a virus which belongs to the genus morbillivirus. this genus, in the family paramyxoviridae, also includes the measles virus (mv), canine distemper virus (cdv), rinderpest virus (rpv), and marine mammal viruses. one of the main features of these viruses is the severe transient lymphopaenia and immunosuppression they induce in their respective hosts, thereby favouring secondary bacteri ... | 2011 | 21371505 |
| sequence and phylogenetic analyses of the structural genes of virulent isolates and vaccine strains of peste des petits ruminants virus from india. | peste des petits ruminants (ppr) is an acute, highly contagious, notifiable and economically important transboundary viral disease of sheep and goats. in this study, sequence and phylogenetic analyses of structural protein genes, namely the nucleocapsid (n), the matrix (m), the fusion (f) and the haemagglutinin (h) coding sequences of virulent and vaccine strains of ppr virus (pprv), were undertaken to determine the genetic variations between field isolates and vaccine strains. the open reading ... | 2010 | 20642492 |
| detection and genetic characterization of peste des petits ruminants virus in free-living bharals (pseudois nayaur) in tibet, china. | peste des petits ruminants (ppr) is an important viral disease of sheep and goats. the wildlife hosts of ppr, which may play an important role in the epidemiology of this disease, are not well characterized. the research was undertaken to study the infection of ppr virus (pprv) in free-living bharals (pseudois nayaur) in tibet, china. in 2007, pprv infection was confirmed in two bharals in rutog county of tibet based on clinical signs and detection of pprv rna in tissue samples. in 2008, pprv in ... | 2011 | 20591454 |
| simultaneous detection of rift valley fever, bluetongue, rinderpest, and peste des petits ruminants viruses by a single-tube multiplex reverse transcriptase-pcr assay using a dual-priming oligonucleotide system. | the aim of this study was to develop a highly sensitive and specific one-step multiplex reverse transcriptase pcr assay for the simultaneous and differential detection of rift valley fever virus (rvfv), bluetongue virus (btv), rinderpest virus (rpv), and peste des petits ruminants virus (pprv). these viruses cause mucosal lesions in cattle, sheep, and goats, and they are difficult to differentiate from one another based solely on their clinical presentation in suspected disease cases. in this st ... | 2011 | 21307219 |
| asian lineage of peste des petits ruminants virus, africa. | interest in peste des petits ruminants virus (pprv) has been stimulated by recent changes in its host and geographic distribution. for this study, biological specimens were collected from camels, sheep, and goats clinically suspected of having pprv infection in sudan during 2000-2009 and from sheep soon after the first reported outbreaks in morocco in 2008. reverse transcription pcr analysis confirmed the wide distribution of pprv throughout sudan and spread of the virus in morocco. molecular ty ... | 2011 | 21762576 |
| Molecular characterization of peste des petits ruminants virus from the Karamoja region of Uganda (2007-2008). | Antibodies against peste des petits ruminants virus (PPRV) were first detected in goats in East Africa in 1995 without any clinical disease. It was not until during the years 2006 and 2007 that the disease outbreaks were first reported in Kenya and Uganda, respectively. This study was carried out to detect and characterize PPRV from a suspected outbreak in sheep and goats in the Karamoja region in 2007-2008. Oculo-nasal and blood samples were tested using F-gene-based primers, and their genetic ... | 2011 | 21979248 |
| history and current status of peste des petits ruminants virus in tanzania. | peste des petits ruminants virus (pprv) causes the acute, highly contagious disease peste des petits ruminants (ppr) that affects small domestic and wild ruminants. ppr is of importance in the small livestock-keeping industry in tanzania, especially in rural areas as it is an important source of livelihood. morbidity and case fatality rate can be as high as 80-100% in naïve herds; however, in endemic areas, morbidity and case fatality range between 10 and 100% where previous immunity, age, and s ... | 2016 | 27770516 |
| sero-epidemiology of peste des petits ruminants (ppr) in pakistan. | a sero survey was conducted during 2005-2006 to estimate the sero prevalence of ppr in the small ruminant population of pakistan. a total of 2798 samples were collected including goats (1979) and sheep (819) from villages in 27 randomly selected districts. these were tested by celisa for pprv and true prevalence estimates were calculated by rogan and gladen estimator. overall, 1273 (45.5%) were found positive; 980 (49.5%) of 1979 samples from goats and 293 (35.8%) of 819 serum samples from sheep ... | 2011 | 21788090 |