Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| properties of aujeszky's disease virus strains isolated from swine pneumonia cases. prelininary report. | 1968 | 4298985 | |
| pseudorabies virus with lost virulence for rabbits after intra-muscular inoculation, obtained from persistently infected cell cultures. | 1968 | 4385165 | |
| resistance of pig tonsillary and throat mucosa to reinfection with a homologous pseudorabies virus strain. | 1970 | 4392072 | |
| [viability of the buk vaccine strain of aujeszky's disease virus in the aerosol state]. | 1970 | 5421600 | |
| swine interferon. i. induction in porcine cell cultures with viral and synthetic inducers. | the production of interferon by porcine kidney (pk(15)) cell culture in response to viral and synthetic inducers was studied. the inducers used included a synthetic double-stranded polyribonucleotide, polyriboinosinic-polyribocytidylic acid (poly i:c), swine influenza virus and three strains of pseudorabies virus. following exposure to these inducers cell culture fluids were examined for interferon by the plaque-reduction method. the poly i:c and the swine influenza virus induced production of i ... | 1972 | 4340345 |
| the effect of colostrum derived antibody on mortality and virus excretion following experimental infection of piglets with aujeszky's disease virus. | 1973 | 4803575 | |
| ultrastructural changes in the lungs of pigs infected with aujeszky's disease virus. | 1973 | 4375836 | |
| the histopathology of experimental pneumonia in pigs produced by aujeszky's disease virus. | 1973 | 4375835 | |
| biological properties of aujeszky's disease (pseudorabies) virus strains with special regard to interferon production and interferon sensitivity. | 1974 | 4837359 | |
| inhibition of herpes virus-induced cell fusion by concanavalin a, antisera, and 2-deoxy-d-glucose. | pseudorabies virus-induced cell fusion in rabbit kidney cells can be prevented by concanavalin a added early after infection. the infected cells are not agglutinated and the infectivity of cell-free virus is not reduced. sera from productively infected animals also inhibit polykaryocytosis, whereas a hyperimmune serum directed against virus structural components has no effect. 2-deoxy-d-glucose reversibly disturbs virus-induced fusion and reduces significantly the virus infectivity. | 1974 | 4858786 |
| [use of temperature, trypsin and biological tests for the intraspecies differentiation of local strains of aujeszky's disease virus]. | studies were carried out with 8 strains of aujeszky's disease virus using a temperature test (50 degrees c for 1 hour), a trypsin test (0.5 mg per cu. cm at 37 degrees c 1 hour), and a biologic test. the strains were isolated from the brain of dead pigs that have presumably been affected with encephalitis. they proved sensitive when studied with the temperature and the trypsin tests sharply lowering their titer. the viruses isolated from pneumonic foci in the lungs of pigs in which the disease h ... | 1975 | 179192 |
| [suitability of immune serums from different animal species for the preparation of conjugates against aujeszky's disease virus]. | a comparison was made of immune serum from rabbits, sheeps, pigs and cattle. pure igg was prepared by the rivanol sulphate method and immune electrophoresis. optimum protein quality, conjugation time under various conditions and using two preparations of fluorescein isothiocyanate were studied. conjugate purified by deae-sephadex a-50 and concentrated to 1% protein by ultrafiltration was freeze-dried and then tested for activity and the degree of non-specific fluorescence. evaluation by yield of ... | 1975 | 172039 |
| [role of the virus of aujeszky's disease in respiratory diseases of swine]. | studies carried out on pig-breeding farms have established the presence of aujeszky's disease virus in cases of bronchopneumonia in pigs. on seven out of eight farms with bronchopneumonia the virus wad demonstrated both virologically and serologically, and nearly 50 per cent of the examined diseased pigs on these and other farms had antibodies. the individual serologic studies of pigs having antibodies revealed that the antibodies appeared in the second month of the animals' fattening. this corr ... | 1975 | 171824 |
| studies on immunity to aujeszky's disease (pseudorabies) virus infection in pigs. | aujeszky's disease is primarily a disease of pigs caused by a herpesvirus. in pigs, the primary site of virus replication is the nasopharynx. some strains cause lesions only in the central nervous system, others cause rhinitis, pneumonia and encephalitis. colostrum from immune sows protected 3 day old piglets from experimental infection, but did not prevent the piglets excreting virus. colostral antibodies were 11-16-fold greater than the serum titres in the sows and the half life of passiveanti ... | 1975 | 165131 |
| latent pseudorabies virus infection in pigs. | latent infection with the top strain of pseudorabies virus (prv) was established in 6 weeks old piglets. infectious virus was found in oropharyngeal swabs till day 10 post infection (p.i.); later on, attempts to detect the virus remained unsuccessful. however, prv could be isolated by explantation of tonsils, cervical lymph nodes, nasal mucosa and gasserian ganglia. these tissues were removed between 160 and 181 days p.i., during cultivation, infectious prv was released into the culture fluid fr ... | 1976 | 9801 |
| demonstration of a herpesvirus from piglets with lesions of aujeszky's disease in new zealand. | 1976 | 189261 | |
| a comparative examination of swine sera for antibody to aujeszky virus with the conventional and a modified virus-serum neutralization test and a modified direct complement fixation test. | 1976 | 181975 | |
| influence of deae dextran upon pig lymphocyte stimulation by aujeszky disease virus antigen. | 1977 | 203145 | |
| comparative susceptibility of rabbits, rats, mice and pigs to infection with aujeszky diseases virus (adv) in the development of an efficacy test for adv vaccines. | 1977 | 202116 | |
| [use of the plaque method for isolating aujeszky's disease virus from meat, organs and meat products]. | comparative virologic studies were carried out to isolate the virus of aujesky's disease from meat, viscera, and raw smoked products by the plaque method as modified by sullivan and read as well as by the method with which the presence of the virus is recorded visually by the cytopathic effect observed in the infected cell monolayer. it was found that at the veterinary and sanitary inspection of meat and meat products produced from diseases or survived animals the modified plaque method proved m ... | 1977 | 202066 |
| [studies of the cft in the diagnosis of aujeszky's disease virus in swine]. | it was found that the complement-fixation test is a prompt and suitable method in the diagnosis of the aujeszky's disease virus, the antigen employed being a cell culture virus. a virulent virus, a slightly virulent one, and the vaccinal mutant strain mk have shown a good complement-fixing activity and they detect specific complement-fixing antibodies in the immune serum. by means of cross cft an antigenic relation has been established between some strains of the herpes group and the aujeszky's ... | 1977 | 199985 |
| immunoglobulin classes of antibodies in milk of swine after intranasal exposure to pseudorabies virus or transmissible gastroenteritis virus. | experiments were conducted to evaluate whether infection of the respiratory tract of pregnant swine with pseudorabies (pr) virus would induce the secretion of immunoglobulin a (iga) antibodies in their milk as was observed after enteric infection with transmissible gastroenteritis (tge) virus. the immune response of sows to pr virus inoculated intranasally and to tge virus inoculated orally/intranasally or via a natural infection was studied. emphasis was placed upon titers and ig classes of pr ... | 1977 | 197014 |
| [virus-neutralizing antibodies in the colostrum and milk of brood sows vaccinated with an ethanol vaccine against aujeszky's disease virus]. | the experiment was carried out with five pregnant sows vaccinated with an etanol vaccine against the aujeszky's disease virus. studies was the level of virus-neutralizing antibodies in the blood, colostrum and milk serum of the sows as in the serum of their piglets. virus-neutralizing antibodies were contained in high titers both in the blood, colostrum, and milk serum of the sows and in the serum of the offsprings. the titer of the passively acquired antibodies in the blood serum of the sucklin ... | 1977 | 204104 |
| pseudorabies virus associated with abortion in swine. | 1978 | 203566 | |
| immunological experimental arthritis in pigs. iv. reaction of the synovial membrane of the non-immunized and immunized pigs after intraarticular administration of the virus of aujeszky's disease. | 7 days after intramuscular administration of the attenuated virus of aujeszky's disease, strain tk 300 l, it was found: in non-immunized animals--immunological arthritis with fibrinoid necrosis and abundant infiltrations from lymphoid cells; in animals of low antibodies titer--only few infiltrations from lymphoid and plasmic cells round the sub-synovial vessels; in animals of high antibodies titer--vast areas of fibrinoid necrosis, abundant infiltrations from lymphoid cells and presence of gigan ... | 1978 | 219813 |
| immunological experimental arthritis in pigs. iii. inflammatory reactions in the brain of pigs immunized with the attenuated virus of aujeszky's disease. | histopathological brains and spinal cords of pigs were examined at different times of immunization with the virus of aujeszky's disease (ad). temporary inflammatory reaction was found to have the features of non-suppurative disseminated inflammation in the second week after the second virus dose had been given. perivascular and subependymal lymphocytic infiltrations were observed and the focal multiplication of microglia. | 1978 | 219812 |
| comparison of pseudorabies virus inactivated by bromo-ethylene-imine, 60co irradiation, and acridine dye in immune assay systems. | pseudorabies virus infections among animals, especially swine, have become prevalent in the united states in the past few years. the disease in swine is now economically important. test systems and antigens are being developed for use in control and disease suppression efforts. pseudorabies virus was inactivated by three methods: chemically, with bromo-ethylene-imine; physically, with 60co irradiation; and chemically and physically, with 3,9-diaminoacridine dye followed by exposure to white visi ... | 1978 | 215603 |
| [immune response of pigs to aujeszky disease virus and swine influenza virus]. | explored was the possibility of simultaneous vaccination of pigs against the aujeszky's disease virus and the swine influenza virus. used were strain mk-25 against the former and strain 3sb against the latter. it was found that at the simultaneous subcutaneous or oral treatment with the two antigens equally effective immunity was built as in the case of vaccination with each one of them used alone. no antagonism was established between the two antigens during the time of immunity building in the ... | 1978 | 214936 |
| immune responses in swine given lipid-conjugated pseudorabies viral antigens. | the immune response was compared in pigs given inactivated pseudorabies virus (prv) antigens (with or without adjuvant) or prv antigens covalently conjugated with a fatty acid (lauric acid) to enhance delayed-type hypersensitivity. the pigs were given 2 inoculations, 14 days apart, and were challenge exposed 28 days after the 1st inoculation. pibs inoculated with prv antigens, with or without adjuvant, had significant virus-neutralizing (vn) antibodies before challenge exposure, but the pigs ino ... | 1978 | 211887 |
| virus isolation and immune responses in susceptible swine exposed with pseudorabies virus (shope strain). | eighteen seronegative swine weighing from 9 to 11 kg were exposed intranasally with the shope strain of pseudorabies virus (prv) and were observed for 21 days in an experiment to detect virus shedding and immune responses. all swine had prv in their nasal passages at 7 days after exposure; they also had precipitating antibodies to prv as determined by the microimmunodiffusion test (midt) and very low levels of virus-neutralizing (vn) antibodies. the prv was isolated from only 2 swine at postexpo ... | 1978 | 211884 |
| [vaccination of piglets of different ages with inactivated aujeszky's disease vaccine]. | 1979 | 231429 | |
| pseudorabies: adaptation of the countercurrent immunoelectrophoresis for the detection of antibodies in porcine serum. | a countercurrent immunoelectrophoresis test was developed for the detection of precipitating antibodies to pseudorabies virus in pig serum. the precipitation reaction occurred only between the pseudorables antigen and the homologous porcine antiserum. the sensitivity of the method was compared to that of the serum neutralization test. on the basis of its sensitivity, its specificity and the rapidity with which the results were obtained, the countercurrent immunoelectrophoresis may become a poten ... | 1979 | 227550 |
| colostral immunity in piglets from sows vaccinated with inactivated aujeszky disease virus vaccine. | neutralizing antibodies against adv were transmitted from sows, vaccinated with inactivated adv adjuvanted with deae dextran, to their offspring via colostrum. the suckling piglets were protected by colostral immunity against contact infection with adv at week 1 p.p., however, they were not protected against i.n. infection (10(8) tcd50). at 2 and 3 weeks p.p. all the piglets were protected against both contact infection and i.n. infection. at 4 weeks p.p. 50 per cent of the litter were protected ... | 1979 | 226031 |
| [inoculation of swine with inactivated aujeszky vaccine: reduction of the inoculation dose, a cutaneous allergy test and the effect of vaccination on viremia]. | 1979 | 231509 | |
| [treatment of aujeszky's disease in a pig breeding farm]. | 1979 | 229584 | |
| latency in pseudorabies vaccinated pigs. | 1979 | 233387 | |
| test and removal procedures vs vaccination for control and eradication of pseudorabies in missouri. | 1979 | 233388 | |
| a seroepizootiologic study of five viruses in a swine-evaluation station. | this serologic study was done to gain information on the spread, maintenance, and effect upon performance of five porcine viruses. blood samples were taken from two groups of 8- to 11-week-old pigs from a large number of indiana swine herds in a performance-testing station 1 week after entry, 7 weeks after entry (one group only), and at slaughter. the sera were tested by indirect fluorescent antibody tests for antibodies to transmissible gastroenteritis virus (tgev), swine influenza virus (siv), ... | 1979 | 230762 |
| latent pseudorabies virus infection in swine detected by rna-dna hybridization. | 1979 | 230759 | |
| [certain properties of the aujeszky live vaccine "dessau" with special reference to laboratory diagnostic aspects]. | aujeszky live vaccine "dessau" proved to be apathogenetic to and unconditionally tolerable by pigs of all age groups, including pregnant sows. transmission of herpes virus suis vaccine strain from immunised individuals to non-immunised contact animals was not observed at all. higher titres of virus-neutralising serum antibody with longer persistence were not attained until repeated vaccinations had been applied, using aujeszky live vaccine "dessau". spherical detachment of single cells was the o ... | 1980 | 6251770 |
| [aujeszky's disease: vaccination problems and vaccination advice]. | 1980 | 6243807 | |
| [serological investigations for detection of neutralising antibodies against the virus of aujeszky's disease in pedigree breeding - and piglet producing farms in the district of the animal health office in the chamber of agriculture weser-ems (author's transl)]. | 1980 | 6249563 | |
| detection of pseudorabies virus antibodies: time of appearance by two serotests. | this report describes a time-course comparison of detection of pseudorabies virus antibodies in experimentally infected swine by the virus-neutralization (vn) and indirect hemagglutination tests. specific antibody titers were observed by the iha test at 5 days after swine were inoculated, but not until 12 days by the vn test. the predominant immunoglobulin (ig) class present in the serums of the swine at 5 and 7 days after inoculation was igm, as determined by sulfhydryl reductions. the vn test ... | 1980 | 6255835 |
| [the rotating aeration (system fuchs) for treatment of liquid animal and municipal wastes. 9. report: the effect of aerobic treatment of pig slurry containing pseudorabies virus]. | 1980 | 6250530 | |
| [vaccination in aujeszky's disease on enzootic fattening farms]. | an experiment was carried out on 125 pigs, originating from immune mothers on an enzootic for a. d. swine-breeding farm. the pigs were vaccinated once and twice with living vaccine mk-25 at different moments after their weaning. on the 180th after the vaccination the pigs were infected with a virulent (10(6) tcid) pseudorabies virus. they were studied clinically, serologically, virologically and pathomorphologically. it was proved that the vaccination of pigs, born by immune mothers, did not bri ... | 1980 | 6259802 |
| [hematological studies of pigs vaccinated against aujeszky's disease]. | hematological investigations within a period of six months were carried out on 4 groups of pigs vaccinated with different doses of living aujeszky mk-25 vaccine. the pigs from groups i and ii were vaccinated with a normal dose of 2 cm3, the pigs from group iii--with 10 doses, whereas those from group iv--with a hundredfold dose. a clearly pronounced immunohemolytic anemia was proved, accompanied by leucocytopenia with an increased percentage of segmental-nuclear leucocytes and monocytes during t ... | 1980 | 6262996 |
| comparison of the effect of trisodium phosphonoformate on the mean plaque size of pseudorabies virus, infectious bovine rhinotracheitis virus and pigeon herpesvirus. | 1980 | 6268670 | |
| epidemiologic monitoring following an episode of pseudorabies involving swine, sheep, and cattle. | in april 1978, an episode of pseudorabies involved swine, sheep, and cattle on a farm in north-central missouri. the herd of 48 farrowing sows was vaccinated, then separated from the sheep and cattle by double fencing. within 4 days, death losses in sheep and cattle ceased, indicating that separation by double fencing is an effective means of controlling interspecies virus spread. monitoring of pseudorabies in sows and their vaccinated offspring was done by serum neutralization testing and virus ... | 1980 | 7380713 |
| enzyme linked immunoassay and fluorescent antibody techniques in the diagnosis of viral diseases using staphylococcal protein-a instead of anti-gamma-globulins. | staphylococcal protein-a (spa) is known to interact with the crystallizable fragment (fc) of igg molecules from several species. in the present study, spa coupled to either fluorescein isothiocyanate (fitc) or peroxidase was used in place of antisera to igg for the fluorescent antibody (fa) techniques and the enzyme linked immunoassay (elisa). the spa conjugates produced low background staining when applied in these techniques, and provide a rapid, highly specific and sensitive means for the ide ... | 1980 | 15612263 |
| skin test as herd diagnosis for aujeszky's disease (pseudorabies) in swine. | summary the value of a skin test for the diagnosis of aujeszky's disease (pseudorabies) in swine was examined. semipurified and concentrated antigens, obtained by ether/tween 80 inactivation of aujeszky's disease virus, were inoculated intradermally into seronegative, experimentally infected and vaccinated swine and into pigs with maternal antibodies. a specific skin reaction, characterized by a visible indurated swelling, was observed within 24 hours in animals with active immunity, no reacti ... | 1980 | 22039900 |
| pneumonia of pigs: a review. | pneumonia of pigs is one of the more important disease factors limiting pig production. of the varieties of pneumonia affecting this species enzootic pneumonia caused by mycoplasma spp. is the most common and most important. the major effects of this disease are lowered food conversion ratio and poor weight gain. deaths are usually the result of secondary infection by necrotising, pus-forming bacteria. eradication of the disease is expensive and requires depopulation and restocking. control and ... | 1981 | 16030803 |
| mechanisms of infection in the respiratory tract. | related to its potential vulnerability the respiratory tract has a very complex and effective defence apparatus. the interaction between these defence mechanisms and certain characteristics of aetiological agents results in a pattern in which initial infections by these agents tend to occur at specific sites in the tract. infections in which the primary portal of entry is in the upper respiratory tract include bordetella bronchiseptica and haemophilus spp in pigs; pasteurella spp in cattle, shee ... | 1981 | 16030806 |
| pseudorabies in a dog. | pseudorabies was diagnosed in a 5-year-old female crossbred dog by histologic examination and virus isolation. the clinical signs were depression, salivation, head pressing, and emesis. there were no gross pathologic findings. the microscopic findings in the brain stem consisted of mononuclear cell infiltrates in the leptomeninges, subarachnoid space, and neuropil. in addition, there were mononuclear cell perivascular cuffs, focal areas of gliosis, neuronal degeneration, and acidophilic intranuc ... | 1981 | 7275753 |
| an incidence of pseudorabies (aujeszky's disease) in piglets in japan. | 1981 | 6283221 | |
| [field experience using an inactivated vaccine in aujeszky's disease vaccination of cattle (author's transl)]. | in the autumn of 1979, approximately, 400 animals on twenty farms were inoculated twice against aujeszky's disease using an inactivated vaccine in a practice in the achterhoek (province of gelderland). the animals vaccinated were mainly yearlings and heifers on farms on which cattle and pigs could not be effectively separated. adverse reactions to vaccination, other than a slight to moderate increase in body temperature, were not observed. outbreaks did not occur in vaccinated cattle during the ... | 1981 | 6270844 |
| [comparative studies of porcine sera with an immunoenzyme test (elisa) and neutralization test for serodiagnosis of aujeszky's disease in swine]. | 1981 | 6273100 | |
| hog cholera antibodies in pigs vaccinated with an aujeszky-vaccine based on antigen produced in ib-rs-2 cells. | 1981 | 6283854 | |
| studies on the role of humoral and cell-mediated immunity in pigs after vaccination with aujeszky's disease virus. | humoral and cellular immunity in pigs vaccinated twice with aujeszky's disease virus (adv) was studied by seroneutralizing test and direct leucocyte migration inhibition technique. significant migration inhibition of leucocytes (lmi) was found on the fifth day, whereas specific antibodies began to appear at that time only in very low titers. anamnestic reaction due to the second injection of adv did not bring about a significant increase of migration inhibition of leucocytes, instead the level o ... | 1981 | 6291846 |
| studies on the virulence of aujeszky's disease virus strains isolated from swine. | 1981 | 6307023 | |
| [comparison of 2 inactivated vaccines against aujeszky's disease in pigs]. | equal efficiency was proved by comparing two inactivated vaccines against aujeszky's disease (ad) virus manufactured in czechoslovakia. fifteen porkers at the age of four weeks were included in the experiment, not possessing any specific antibodies to ad virus. each vaccine was inoculated intramuscularly to five porkers (2 ml) in the interval of three weeks. the third group of five porkers was control. the samples of blood serum were subjected to the serum neutralizing test and radioimmunoassay ... | 1981 | 6267763 |
| [aujeszky's disease: maternal immunity of piglets born of sows inoculated with various vaccines (author's transl)]. | studies on the maternal state of immunity were done in 4-10 week-old piglets born of vaccinated sows free from aujeszky's disease. the sows were inoculated with three different vaccines: two live vaccines (aescovac aujeszky) and the mk25 vaccine) and an inactivated vaccine (geskyvac). the maternal state of immunity of the piglets was assessed from the titre of the virus-neutralizing (vn) antibodies in the blood. to do so, samples were taken from 300-400 4-10-week-old piglets per vaccine inoculat ... | 1981 | 6269251 |
| aujeszky's disease: recent advances and current problems. | 1981 | 6278375 | |
| [use of the passive hemagglutination reaction to study aujeszky's disease]. | experiments were carried out with the use of the passive hemagglutination test to study aujeszky's disease, the antigen employed being the avirulent mk-35 strain of the disease virus. it was established that the passive hemmagglutination reaction could be referred to as a specific and rapid method in the study and diagnosis of the disease. results showed that the vaccinal mk-35 strain was successfully used as an antigen in the test. in the treatment with an mk-25 vaccine there were predominantly ... | 1981 | 6272472 |
| [creation of an avirulent mutant of aujeszky's disease virus by exposure to 5-bromodeoxyuridine]. | a mutant with new biologic properties has been obtained at the cultivation of a virulent strain of the aujeszky's disease virus in chick embryo fibroblast cultures, following a definite number of passages. it has proved resistant when culturing at the present of 5-brom-desoxyuridine and 5-iod-2-desoxyuridine, retaining its infections titer. it produces small plaques and destroys cell cultures of a tiny granular structure, the plaque-forming titer being 5. 6x10-7. the mutant has been shown to be ... | 1981 | 6272474 |
| [comparative pathomorphological studies of piglets infected with different strains of the pseudorabies virus]. | studied were morphologically the central nervous system and the internal organs of a total of 40 experimentally infected pigs-10 infected with the virulent strain b (5.2 c 10(6) pfu), 10 infected with the slightly virulent strain k (4.8 x 10(6) pfu), and 20 infected with the vaccinal mutant strain mk 25 (2.4 x 10(6) pfu), along with 4 control pigs. histologically, all treated animals showed changes in the central nervous system characteristic of nonsuppurative meningoencephalitis. the lesions we ... | 1981 | 6274081 |
| isolation of transmissible gastroenteritis virus, pseudorabies virus, and porcine enterovirus from pharyngeal swabs taken from market-weight-swine. | pharyngeal swab samples were collected at a central iowa abattoir from 6,010 market-weight slaughter hogs from september 1, 1979 to august 31, 1980. the swab samples were examined for cytopathic viruses by inoculation of monolayer cultures of continuous line of swine testicular cells. of the 6,010 swab samples tested, transmissible gastroenteritis virus was isolated from 91 (1,51%), pseudorabies virus was isolated from 431 (7.17%), and porcine enterovirus was isolated from 21 (0.35%). although a ... | 1981 | 6278996 |
| enzyme-linked immunosorbent assay for detecting antibodies to aujeszky's disease virus in pigs. | an indirect micro enzyme-linked immunosorbent assay (elisa) for detecting antibodies to aujeszky's disease virus in pigs is described. a control antigen prepared from infected cells was included for each serum tested. of 243 sera from serologically positive farms, 175 (72 per cent) and 147 (60 per cent) were positive by the elisa test and microtitre serum neutralisation test, respectively. failure to include a control antigen for each serum would have resulted in 14 sera (6 per cent) being diffe ... | 1981 | 6280368 |
| isolation of aujeszky's disease virus from boar semen. | 1981 | 6282077 | |
| induced latency in pseudorabies vaccinated pigs. | a latent pseudorabies virus infection was established in pigs despite vaccination with a modified-live pseudorabies virus vaccine. although the vaccinated pigs developed high concentrations of antibody, virus was recovered from the tonsils and lungs of pigs treated with dexamethasone three months after inoculation with virulent virus. these results may explain why vaccination programs have failed to eliminate the persistence and spread of virulent pseudorabies virus in infected herds. | 1981 | 6268266 |
| [immunohistologic antigen demonstration and virus isolation in cell cultures in aujeszky disease]. | 1981 | 6264912 | |
| [the effect of vaccination on the intrauterine transmission of aujeszky's disease virus in sows]. | eight of ten sows of the large white breed were vaccinated in different stages of pregnancy, with an inactivated vaccine against aujeszky's disease. the other two sows remained untreated. two virulent strains of the aujeszky's disease virus were used for the infection of all sows, either orally or intravenously. neither of the two ways of infection led to the transmission of the virus to the foetus in any of the eight vaccinated sows. on the other hand, in the two unvaccinated sows, the virus wa ... | 1981 | 6266115 |
| [aujeszky's disease: serological responsiveness after vaccination of 6-10-week-old piglets with maternal antibody (author's transl)]. | trials were made to study the extent to which 6-10-week-old piglets with and without virus-neutralizing (vn) antibodies are capable of a serological response to vaccination. the piglets were inoculated with three different vaccines: two live vaccines (aescovac aujeszky and mk25 vaccine) and an inactivated vaccine (geskyvac). the titre of virus-neutralizing antibody in the blood was determined for each vaccine in approximately 200 piglets at the time of inoculation as well as within four and twel ... | 1981 | 6269250 |
| [biological properties of the mk 35 mutant of aujeszky's disease virus (pseudorabies virus)]. | clinical, virological, and morphological studies were carried out with a total of 15 twenty-day-old pigs and 55 rabbits of 2.5 kg body weight. all were experimentally infected with a new mutant, mk 35 (3.5 x 10(7) plaque forming units) of the pseudorabies virus. the changes taking place in the test animals were followed up in their dynamics from the first to the thirtieth day after injecting the virus. no clinical signs speaking of the development of aujeszky-s disease were noted, neither was th ... | 1981 | 6272477 |
| [aujeszky disease in pigs: practicability of an elisa for detection of serum antibodies (author's transl)]. | 1981 | 6262038 | |
| resistance of porcine preimplantation embryos to pseudorabies virus. | 1981 | 6275748 | |
| [serological studies on the prevalence of neutralizing antibodies against pseudorabies virus in pigs in hessen (author's transl)]. | 1981 | 6263571 | |
| laboratory evaluation of selected disinfectants as virucidal agents against porcine parvovirus, pseudorabies virus, and transmissible gastroenteritis virus. | of a variety of disinfectants evaluated, only sodium hypochlorite and sodium hydroxide inactivated porcine parvovirus (ppv) after a 5-minute incubation period. after the same incubation time, pseudorabies and transmissible gastroenteritis viruses were inactivated by all of the disinfectants tested. when the incubation time was increased to 20 minutes, 2% glutaraldehyde and a double-strength concentration of a commercial formaldehyde preparation also inactivated ppv. formaldehyde vapor and ultrav ... | 1981 | 6269467 |
| immunogenicity of bivalent vaccine for reproductive failure of swine induced by pseudorabies virus and porcine parvovirus. | 1981 | 6277213 | |
| [comparative study of the antiviral activity of pancreatic and microbial rnase]. | the efficacy of pancreatic rnase with microbial enzymes (rn-ases) of act. rimosus and bacillus intermedius) was studied comparatively in vitro in a transplantable cell culture of the swine embryokidney with respect to the aphthosa virus (av) and the virus of the aujeszky disease (vad). the vad proved to be most sensitive to rnases. rnase of bac. intermedius showed the highest antiviral efficacy. the enzymes were active in vivo, when the albino mice and newborn rabbits were infected with the av, ... | 1981 | 6267996 |
| comparison of a direct radioimmunoassay with virus isolation in cell culture for detection of pseudorabies virus in tissues of infected swine. | a direct radioimmunoassay (dria) was developed for detection of pseudorabies virus (prv) in tissues of pigs with clinical disease. homogenates of tissues prepared from 289 swine were tested for prv with the dria and virus-isolation technique (vit). the virus was detected in 53 (18%) of the homogenates by both dria and vit. fifteen (5%) others were positive for prv by vit, but negative by dria. there were no samples negative by vit and positive by dria. a total of 221 (77%) pigs with clinical prv ... | 1982 | 6280535 |
| isoelectric focusing of infectious particles of porcine pseudorabies virus strains in granulated dextran gels. | isoelectric focusing of infectious particles of four strains of porcine pseudorabies viruses (indiana, iowa, shope and an avirulent live-virus vaccine strains) are described. the pseudorabies virus strains exhibited great mobility in the electric field typical of viruses of the herpes group. strains were considered electrophoretically homogeneous based on their respective isoelectric points. maximal virus infectivity was concentrated in reproducible, stationary zones representing 73 to 86% of th ... | 1982 | 6280822 |
| [aujeszky's disease of swine--demonstration of specific antibodies in organs with elisa]. | 1982 | 6290170 | |
| [control of enzootic aujeszky's disease on pig farms]. | virologic and serologic investigations were carried out to demonstrate the persistence of the virulent virus of aujeszky's disease. threefold vaccinations were conducted with a live vaccine, embracing all animals on the farm and those that were born during the time when sanitation measures were applied. the first vaccination of the sucking pigs was performed with 10 doses of the vaccine in each case. during the time of applying sanation measures the farm was kept closed, the pigs after weaning b ... | 1982 | 6291224 |
| [vaccines against aujeszy's disease]. | 1982 | 6299851 | |
| [control of latent enzootic aujeszky's disease]. | an attempt was made on a swine-breeding complex, where the virus of aujeski's disease was demonstrated to interrupt the inapparent epizootic process of the disease. the persistence of the virus on the complex was demonstrated via virologic investigations of organs of pigs with respiratory symptoms and studies of sera of various groups of animals. a batch of pigs was divided into three groups of which one was left untreated, one was vaccinated at the time of weaning, and one was vaccinated at the ... | 1982 | 6291226 |
| [effect of colostral antibodies on the development of immunity in piglets immunized with live vaccine]. | pigs of sows treated with a live vaccine were in turn vaccinated with a live vaccine at different age. part of them were challenged with a virus at 60 days of age, the remaining -- at 90 days. the pigs were kept under clinical observation, and were killed on the 10th day following challenge in order to be thoroughly investigated. it was found that the passive immunity (virus-neutralizing antibodies) in pigs of twice (live vaccine) treated sows persisted for 4 to 5 weeks after birth. it dropped s ... | 1982 | 6291227 |
| immunity of pigs vaccinated by live or inactivated aujeszky vaccines against experimental infection. | 1982 | 6299030 | |
| leukocyte migration-inhibition agarose test in swine after vaccination and challenge with inactivated and activated pseudorabies virus. | cell-mediated immunity to pseudorabies virus (prv) was studied by means of the leukocyte migration-inhibition (lmi) agarose test. migration of leukocytes from swine vaccinated with 10 tcid50 inactivate prv and from normal control swine was not inhibited in the presence of specific prv antigen. cellular immune responses were detected in 80% of the vaccinated and 40% of the control group animals at the 1st week after challenge exposure. at the 2nd week, both groups of swine showed a peak level (p ... | 1982 | 6291874 |
| immune response of pigs inoculated with virulent pseudorabies virus and pigs inoculated with attenuated or inactivated pseudorabies virus vaccine before and after challenge exposure. | pseudorabies virus (prv) antibodies, detectable by indirect radioimmunoassay (iria), serum-virus neutralization test (nt), or microimmunodiffusion test (midt) were developed within 8 days after pigs were inoculated with virulent prv or attenuated prv vaccine. indirect radioimmunoassay and nt titers in pigs inoculated with virulent prv were developed at the same rate, with iria titers being higher than nt titers. pigs inoculated with attenuated or inactivated prv vaccine developed peak mean prech ... | 1982 | 6299139 |
| experimental infection of european wild swine (sus scrofa l.) with pseudorabies virus. | experimental infection with pseudorabies virus was carried out by oral exposure of four young wild swine held in contact with two unexposed controls. no disease was observed but virological procedures indicated that the virus was shed in saliva and, in one case, in the nasal discharge, with subsequent infection of the control animals. after slaughter the virus was reisolated from the tonsils but not from lungs and brain. virus reisolation from the tonsils was obtained in two animals after the th ... | 1982 | 6296470 |
| field evaluation of test-and-removal and vaccination as control measures for pseudorabies in missouri swine. | eighteen missouri swine herds were serologically monitored to determine the efficiency of two methods for the control of pseudorabies. a serum neutralization test-and-removal procedure was effective in ten of ten herds using this method. vaccination procedures were less reliable. virus still circulated in five of eight vaccinated herds and a thorough epidemiological evaluation of herd status was impossible. titers caused by vaccination could not be distinguished from those by natural infection. ... | 1982 | 6293689 |
| the incidence of aujeszky's disease in finland. | 1982 | 6294595 | |
| vaccination of cattle against pseudorabies (aujeszky's disease) with homologous virus (herpes suis) and heterologous virus (herpes bovis 1). | study was made to determine whether vaccination of cattle against pseudorabies (pr; aujeszky's disease) affords protection upon subsequent intranasal challenge exposure with virulent virus. vaccinations were performed with a commercially available oil-adjuvant pr virus vaccine, in some cases supplemented with a1(oh)3 (given subcutaneously), with the attenuated nia4 strain of pr virus (given intranasally), and with a commercially available temperature-sensitive mutant of bovine herpesvirus-1 (inf ... | 1982 | 6283963 |
| pseudorabies virus infection in raccoons: a review. | pseudorabies is a rarely reported disease of raccoons. laboratory and field evidence of prv infection suggests the raccoon is a "dead end" host with little opportunity for raccoon-to-raccoon spread of virus. all reported field cases have been associated closely with infected swine and swine have been considered the source of the raccoon infection. the clinical signs of prv in raccoons closely resembles those of canine distemper and rabies virus infections. infection with the latter viruses are c ... | 1982 | 6285008 |
| intranasal vaccination of pigs against aujeszky's disease. 1. comparison of intranasal and parenteral vaccination with an attenuated vaccine in 12-week-old pigs from immunized dams. | 1982 | 6287698 | |
| procedures for the elimination of pseudorabies virus from herds of swine. | 1982 | 6298161 | |
| [replication of the aujeszky virus in vaccinated swine following experimental infection with large and medium amounts of virus]. | 1982 | 6283767 | |
| oronasal challenge of fattening pigs after vaccination with an inactivated aujeszky's disease vaccine. | groups of pigs from vaccinated and unvaccinated sows were vaccinated once or twice between the ages of eight and 20 weeks with a commercial inactivated, oil adjuvanted aujeszky's disease virus vaccine. pigs were challenged by the oronasal route when 22 to 27 weeks old. pigs from unvaccinated sows developed neutralising antibodies after vaccination but no seroconversion was detected in eight-week-old pigs or in 80 per cent of 15-week-old pigs from vaccinated sows. challenge resulted in severe dis ... | 1982 | 6283610 |
| experimental transmission of pseudorabies virus in swine by embryo transfer. | 1982 | 6283958 | |
| horizontal transmission of pseudorabies virus in cattle. | pseudorabies virus (prv) was not transmitted horizontally from 3 prv-infected calves to 2 contact control calves during 4 days of comingling in experiment 1. although these contact control calves developed clinical signs of pseudorabies when infected intranasally with prv in experiment 2, they did not transmit prv to a second pair of contact control calves. however, 1 of 2 pigs comingled with these 4 calves seroconverted. during both experiments, moderate amounts (10(2) to 10(5) tcid50) of prv w ... | 1982 | 6283959 |