Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| viral infection across species barriers: reversible alteration of murine sarcoma virus for growth in cat cells. | infection of cat embryo cells by a centrifugally induced aggregate of murine sarcoma virus and feline leukemia virus gave rise to a defective, focus-forming virus which propagated in cat cells, but not in mouse cells. this virus, apparently enveloped with a feline leukemia virus coat, was later subjected to aggregation with murine leukemia virus, whereupon it regained the capacity for growth in mouse cells. | 1969 | 5793978 |
| serological studies of the feline leukemia virus. | 1970 | 4376371 | |
| comparisons of virus-like particles from leukotic cattle to feline leukosis virus. | 1970 | 4376380 | |
| feline leukemia virus detection in vitro. | 1970 | 5467915 | |
| trans-species rescue of defective genomes of murine sarcoma virus from hamster tumor cells with helper feline leukemia virus. | this report describes a trans-species rescue of defective msv genome with helper leukemia virus derived from cats. this rescue was achieved by in vitro co-cultivation of hamster tumor cells with feline embryo cells in the presence of helper feline leukemia virus (felv), or by inoculation of tumor cells into felv-infected newborn cats. the rescued focus-forming viruses produced foci in feline embryo cultures but not in cultures of mouse, rat, and hamster species. one isolate was tested and found ... | 1970 | 4313195 |
| ultrastructural studies of feline leukemia virus. | 1970 | 4991275 | |
| infection and transformation of dog cells with a modified sarcoma virus. | dog-embryo cell cultures were infected with a mixture of feline leukemia virus (fellv) and a modified murine (moloney) sarcoma virus msv(fellv). morphological alteration of the cells was observed 3 days post infection. virus progeny from the infected cultures increased 50- to 100-fold in foci of cellular alteration on dog cell cultures pretreated with diethylaminoethyl-dextran, but only twofold on cat embryo cultures similarly treated. the numbers of foci produced corresponded to a dual infectio ... | 1970 | 18605433 |
| a fluorescent antibody technique for the detection of the group-specific antigen of feline leukemia virus in infected tissue-culture cells. | 1971 | 4105993 | |
| review of viral disease of cats. | 1972 | 4344966 | |
| human cancer in households containing cats with malignant lymphoma. | 1972 | 4350192 | |
| isolation of human amnion cells transformed by rescuable murine sarcoma virus. | 1973 | 4350532 | |
| fucosylglycolipid metabolism in oncornavirus-transformed cell lines. | 1973 | 4353889 | |
| size differences in the ribonucleic acids of feline leukaemia viruses. | 1973 | 4357376 | |
| rd 114 virus-specific sequences in feline cellular rna: detection and characterization. | rna extracted from cat cells contains sequences homologous to rd-114 viral rna. the sequences are measured by molecular hybridization with a single-stranded dna probe synthesized by the virion polymerase using the endogenous viral rna as template. viral-specific rna has been detected in all cells of cat origin tested thus far, but not in cells of other animals, except for the virus-producing human rhabdomyosarcoma cell, rd-114. the extent of hybridization of the dna probe to cellular rna was equ ... | 1973 | 4358169 |
| interspecies infection by feline leukemia virus: serial cell-free transmission in dogs of malignant lymphomas induced by feline leukemia virus. | 1973 | 4360147 | |
| significance of leukemia in animals for the human disease. | 1973 | 4360150 | |
| electron microscopy of feline leukaemia virus rna. | 1973 | 4360153 | |
| oncogenic activity of feline fibrosarcoma virus in newborn pigs. | 1973 | 4348004 | |
| syncytial giant cell focus assay for viruses derived from feline leukemia and a simian sarcoma. | 1973 | 4348580 | |
| endogenous type c virus from a cat cell clone with properties distinct from previously described feline type c virus. | 1973 | 4122424 | |
| [evidence for the existence of different antigenic determinants of the interspecies type in mammalian rna-c-type tumor viruses. comparative serological studies on viruses of various animal species including a virus suggested to be of human origin (author's transl)]. | 1973 | 4131792 | |
| immunology of oncornaviruses. | 1974 | 4132209 | |
| differences in acute and convalescent-phase antibodies of cats infected with feline picornaviruses. | complement fixation inhibiting and complement-fixing antibodies were demonstrated in sera from cats during the acute and convalescent stages, respectively, of feline picornavirus infections. complement-fixing antibody activity was present in 19s and 7s globulins, whereas complement fixation inhibiting antibody activity was confined to the 7s globulins. sera with complement-fixing antibody and sera with complement fixation inhibiting antibody were also shown to have neutralizing and precipitating ... | 1974 | 4211925 |
| structural polypeptides of primate derived type c rna tumor viruses. | 1974 | 4363057 | |
| editorial: cat leukemia: a threat to man? | 1974 | 4359320 | |
| simple, quantitative assay for both xenotropic murine leukemia and ecotropic feline leukemia viruses. | a cat cell line carrying the genome of a murine sarcoma virus developed discrete foci in linear response to infection with feline leukemia virus or xenotropic murine c-type virus. | 1974 | 4365331 |
| studies on feline lymphosarcoma in the sydney area. | 1974 | 4370400 | |
| editorial: status report: feline leukemia. | 1974 | 4363507 | |
| editorial: the current status of feline leukemia virus research. | 1974 | 4374332 | |
| feline malignant mammary tumors. ii. immunologic and electron microscopic investigations into a possible viral etiology. | 1974 | 4363687 | |
| anemia associated with feline leukemia virus infection in cats. | the types of anemia associated with natural and experimental feline leukemia virus (felv) infection in cats were investigated. in one experiment, 10 kittens were inoculated neonatally with jarrett felv-1, an isolate of subgroup a; 6 developed anemia a few weeks later. this anemia was characterized by macrocytosis, normoblastosis, increased erythropoiesis in the bone marrow, and extramedullary hematopoiesis in the spleen. anemia was transient and nonfatal and occurred before the onset of lympoid ... | 1975 | 163317 |
| evolution of type c viral genes: origin of feline leukemia virus. | reiterated gene sequences related to the rna of feline leukemia virus (felv) are detected in all tissues of domestic cats and their close felis relatives but not in more distantly related felis species. partially homologous viral gene sequences are found in rodent, and particularly rat, dna. together with the immunologic relationships observed between felv and endogenous rodent type c viruses, the results lead to the conclusion that felv-related genes were transmitted from a rodent to cat ancest ... | 1975 | 52892 |
| interspecies antigenic determinants of the reverse transcriptases and p30 proteins of mammalian type c viruses. | the major internal structural proteins (p30) of type c viruses isolated from several mammalian species were studied by radioimmunoprecipitation and competitive radioimmunoassays. three antigenically distinguishable sets of interspecies determinants could be demonstrated by both methods. one set of determinants shared by viruses of rodent origin (mouse and rat) can be detected readily in feline leukemia viruses but not in other type c viral groups. the p30 proteins of murine viruses also contain ... | 1975 | 49443 |
| isolation of mammalian type c rna virus cross-reactive antigen and antibody by immuno-affinity chromatography. | 1975 | 49291 | |
| feline leukemia virus research- an update. | 1975 | 179729 | |
| sarcomas induced in rats by feline rna virus. | 1975 | 169839 | |
| complement-fixation-inhibition as a test for antibodies in cats and humans to c-type rna tumor virus antigen. | the complement-fixation-inhibition (cfi) test was evaluated as a means of detecting humoral antibodies in cat sera and in human sera to mammalian c-type rna virus interspecies antigen(s). cfi antibody titers of greater than or equal 1:2 were detected in sera from all tumor bearing (23) and normal cats (23), however, sera from most germ free cats were negative. when the same cat sera were tested for blocking antibody by the paired radioiodine labeled antibody technique the correlation between the ... | 1975 | 169819 |
| feline oncornavirus-associated cell membrane antigen. iv. antibody titers in cats with naturally occurring leukemia, lymphoma, and other diseases. | cats with naturally occurring leukemia and lymphoma had low or negative humoral antibody titers to the feline oncornavirus-associated cell membrane antigen (focma). geographic differences were seen in the relative frequencies of various forms of lymphoproliferative neoplasms. lymphatic leukemia and thymic lymphoma were most common in boston, whereas alimentary lymphoma was most frequent in glasgow. no significant differences were found in geometric mean focma antibody titers for the various form ... | 1975 | 169377 |
| [proceedings: some biochemical properties of bovine leukemia virus]. | 1975 | 50808 | |
| lymphocyte mitogen reactivity in feline leukemia virus-infected cats and identification of feline t and b lymphocytes. | 1975 | 183735 | |
| surface properties of mammalian c type viruses. | 1975 | 183712 | |
| comparative epidemiological aspects of naturally occurring malignant lymphoma in domestic cats and rhesus monkeys. | 1975 | 183676 | |
| the epidemiology of feline leukemia virus infection. | 1975 | 183672 | |
| biologic and immunologic response of cats to experimental infection with feline leukemia virus. | 1975 | 183666 | |
| horizontal transmission of feline leukemia virus in cats. | traditionally, cancer has not been considered an infectious disease although some multiple cases of leukemia in man and cattle have been reported. the discovery that feline lymphosarcoma was associated with an rna virus (feline leukemia virus(felv)) meant that infectious transmission of the disease was a possibility. the critical question was whether the predominant method of transmission from one animal to another was 'vertical' (via the gametes) or 'horizontal' (via contagion or infection). a ... | 1975 | 169834 |
| establishment of two canine sarcoma cell lines: productive infection with feline leukemia virus. | two canine sarcoma cell lines (11028, 11031) were established in vitro and have been transferred 213 and 306 times, respectively, since 1970. these cell lines had a chromosome pattern consistent with their canine origin. both cultures were infected with feline leukemia virus (felv), which caused a morphologic and karyotypic changes. the cells became rounded after infection with felv and both cultures showed the presence of a single, large, acrocentric chromosome considered to be a marker chromos ... | 1975 | 169374 |
| editorial: leukaemia in animals and man. | 1975 | 169460 | |
| immune response to leukemia virus and tumor-associated antigens in cats. | cats represent an unusually valuable model for studying the role of the immune response to leukemia, lymphoma, and other mesodermal neoplasms. the agents that cause spontaneous feline leukemias, lymphomas, and fibrosarcomas, the feline leukemia and sarcoma viruses, are well characterized. a specific tumor cell membrane antigen, designated the feline oncornavirus-associated cell membrane antigen (focma) has also been described. feline leukemia and feline sarcoma viruses are antigenically indistin ... | 1976 | 56224 |
| feline anemia. | 1976 | 183337 | |
| prevention of the contagious spread of feline leukaemia virus and the development of leukaemia in pet cats. | 1976 | 183148 | |
| feline leukemia virus infection: age-related variation in response of cats to experimental infection. | sixty-seven specific-pathogen-free cats of various ages (newborn, 2 wk, 1 mo, 2 mo, 4 mo, and 1 yr) were inoculated ip with either the rickard (r) or the kawakami-theilen (kt) strain of feline leukemia virus (felv). susceptibility to felv was judged by induction of a) felv group-specific antigens (gsa) in leukocytes, b) felv-related disease, c) antibody to feline oncornavirus-associated cell membrane antigen (focma), and d) virus-neutralizing (vn) antibody. susceptibility to felv-decreased with ... | 1976 | 187771 |
| feline oncornavirus-associated cell membrane antigen. vi. cytotoxic antibody in cats exposed to feline leukemia virus. | feline leukemia virus (felv)-infected specific pathogen-free (spf) cats, normal uninfected spf cats, and healthy cats from leukemic households were tested for antibody reactive to the feline oncornavirus-associated cell membrane antigen (focma)-containing target cell line fl-74 by microcytotoxicity and indirect membrane immunofluorescence. of the infected spf animals, 81% showed concordant reactivity for the two tests. in contrast, only 55% of the healthy cats known to be naturally exposed to fe ... | 1976 | 186623 |
| expression of feline type-c virus in normal and tumor tissues of the domestic cat. | tumor and normal tissues from domestic cats were examined for felv and rd-114 specific nucleic acids and proteins. virus-positive tissues showed a 100- to 200-fold higher level of felv and a 200- to 400-fold higher level of felv p30 than virus-negative tumors and normal cat tissues. in contrast, the levels of rd-114 viral rna and p30 antigen were comparable in the majority of tumorous and normal tissues examined. when the dna of these tissues was examined for felv-related sequences, the virus-po ... | 1976 | 186414 |
| viral diseases of cats: current concepts. | 1976 | 179185 | |
| endogenous rd-114 virus genome expression in malignant tissues of domestic cats. | endogenous xenotropic cat type c virus (rd-114)- and infectious feline leukemia virus (felv)-specific gene expressions were measured in spontaneous sarcomas carcinomas, and nonmalignant cat tissues by molecular hybridization for virus-specific rna and competition radio-immunoassays for the major internal protein (p30) of these two viruses. the results indicate that rd-114 gene expression in sarcomas and carcinomas at both rna and p30 levels is significantly higher than histologically normal tiss ... | 1977 | 197261 |
| inhibition of normal lymphocyte mitogenic reactivity by serum from feline leukemia virus-infected cats. | the effect of serum from 12 cats with lymphosarcoma induced by feline leukemia virus (felv) on the response of normal cat peripheral blood lymphocytes to phytomitogen-induced blastogenesis was studied. the majority of felv sera, when tested at a concentration of 20% of the incubation medium, caused a 40 to 70% reduction in the mean blastogenic response to concanavalin a compared to the response obtained with a similar concentration of normal feline serum. results with pokeweed mitogen were simil ... | 1977 | 198125 |
| horizontal transmission of feline leukemia virus under natural conditions in a feline leukemia cluster household. | ten post-weanling 4-month-old cats, designated "tracers", were placed in a feline leukemia cluster household to determine the efficiency of horizontal transmission of feline leukemia virus (felv). the tracer cats were confirmed as negative for prior exposure to felv. following the placement in the leukemia cluster environment, the tracer cats were serologically monitored at intervals of 3-6 weeks for a total period of 1 year. the tests employed included the detection of felv using fixed-cell imm ... | 1977 | 188773 |
| [comparative study of oncornavirus type d polypeptides]. | 1977 | 198961 | |
| protection of kittens from feline leukaemia virus infection by maternally-derived antibody. | 1977 | 199981 | |
| feline oncornavirus-associated cell membrane antigen: evidence for an immunologically crossreactive feline sarcoma virus-coded protein. | the feline oncornavirus-associated cell membrane antigen (focma) acts as a target for natural immuno-surveillance against tumor development in the cat. in the present study, mink and rat cells nonproductively transformed by feline sarcoma virus (fesv) were shown to express focma as well as 5'-terminal feline leukemia virus (felv) gag gene proteins, p15 and p12. in contrast, such cells lack detectable levels of other felv gag gene-coded proteins or the env gene product, gp70. focma, p15, and p12 ... | 1977 | 202959 |
| felv epidemiology in los angeles cats: appraisal of detection methods. | we investigated the reliability of the fixed cell indirect fluorescent antibody (ifa) peripheral blood smear test as an index of systemic infection with felv. positive results with this test were found to correlate well with detectable felv p30 antigen in bone-marrow smears by ifa, in serum and tissue by competition immunoassays, and with type-c particles in bone marrow or spleen by electron microscopy. most cats with lymphoma, anemia or infectious peritonitis were positive for felv and showed a ... | 1977 | 191415 |
| retinal neoplasia and dysplasia. i. induction by feline leukemia virus. | feline leukemia virus, a naturally occurring c-type virus (oncorna virus), was injected systemically and intraocularly into fetal and newborn kittens. a light microscopy study of the resultant ocular tumor changes was carried out. one animal developed an intraocular tumor of apparent retinal origin. eight animals showed intraocular neoplastic cell infiltration. the most common ocular change observed was retinal dysplasia. sequential histologic examination of enucleated eyes showed diffuse intrao ... | 1977 | 191424 |
| feline leukemia virus. its related diseases and control. | 1977 | 191976 | |
| expression of feline leukaemia virus antigens on cat lymphoma cells: kinetics of biosynthesis. | 1977 | 69678 | |
| horizontal transmission of feline leukemia virus under experimental conditions. | thirty-seven specific-pathogen-free (spf) cats ranging from newborn to 1 year were inoculated with the rickard strain of feline leukemia virus (felv). each inoculated cat shared a cage with a control spf cat for 40 weeks post inoculation. after 4-5 weeks, 20 of the inoculated cats became group-specific antigen (gsa)-positive; the other 17 remained gsa-negative but developed virus neutralizing and feline oncornavirus cell membrane-associated antigen antibody titers. seventeen of the control cats ... | 1977 | 189052 |
| rejectability of virus-induced tumors and nonrejectability of spontaneous tumors: a lesson in contrasts. | in contrast to the excellent surveillance against tumors induced by the ubiquitous viruses in their natural host species, spontaneous tumors developing naturally, without experimental interference, evoke little or no rejection reaction. this may be viewed in relation to the natural history of tumors. in most cases, tumors evolve in several steps, with a successful of clonal variants following each other, characterized by increasing independence of host regulations (including immune restrictions) ... | 1977 | 194366 |
| passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated. | antibodies against feline leukemia virus (felv) and the feline oncornavirus-associated cell membrane antigen (focma) were transferred from pregnant cats to their suckling kittens. all of these kittens were protected against infection and oncogenesis by virulent felv when challenged at 2 weeks of age. suckling kittens acquired 25 to 100% of maternal virus-neutralizing and focma titers by 3 days of age, and titers underwent linear decay to undetectable levels by 2 to 3 months of age. focma antibod ... | 1977 | 194840 |
| modifications of the immunofluorescence assay for feline leukemia virus group-specific antigens. | observations and minor modifications are presented concerning the immunofluorescence assay for feline leukemia virus (felv) group-specific antigens (gsa) in blood cells of cats. data are given regarding absorption of goat felv gsa antiserum in vivo in cats, absorption of the antiserum in vitro with feline blood cells, and the comparative efficacy of various chemical fixatives in preservation of felv gsa for immunofluorescent staining. the best results were obtained with in vitro absorption of an ... | 1978 | 219732 |
| characterization of feline glomerulonephritis associated with viral-induced hematopoietic neoplasms. | light, electron, and immunofluorescence microscopy on tissues from 63 domestic cats revealed that glomerulonephritis occurred in almost one third of cats with hematopoietic neoplasms of the type linked with feline leukemia virus (felv). glomerular lesions were of the immune complex type with subepithelial, subendothelial, and mesangial dense deposits and reticular aggregates, similar to the nephropathy associated with systemic lupus erythematosus in humans. evidence that the glomerular lesions m ... | 1978 | 677265 |
| the occurrence of feline leukaemia virus neutralizing antibodies in cats. | 1978 | 212375 | |
| characterization of a feline sarcoma virus-coded antigen (focma-s) by radioimmunoassay. | a radioimmunoassay has been developed that detects a unique antigen encoded by the genome of the feline sarcoma virus (fesv). pseudotype viral particles containing an fesv-specific polyprotein (p85) were used both as a source of antigen and to prepare specific antisera in rabbits. because p85 contains antigens related to two structural proteins (p15 and p12) of feline leukemia virus (felv), antibodies directed to these were adsorbed with purified felv proteins. the adsorbed rabbit antiserum boun ... | 1978 | 212755 |
| applied viral immunology. | 1978 | 220771 | |
| immunologic methods for the detection of humoral and cellular immunity. | a variety of immunologic techniques have been introduced during the past few years. many of these techniques are being applied to clinical specimens in an attempt to help the practicing veterinarian make a diagnosis. the introduction of new techniques requires extensive testing with clinically normal and diseased patients. it is essential for the practicing veterinarian to understand that the techniques available for the detection of immunologic disorders in the dog and cat are not routine diagn ... | 1978 | 220772 |
| [feline leukemia: recent developments on the causes and immunoprevention of the disease (author's transl)]. | 1978 | 230008 | |
| cat leukemia and the cluster controversy. | 1978 | 204405 | |
| a portion of the feline leukaemia virus genome is not endogenous in cat cells. | although viral sequences closely related to feline leukaemia virus are represented in multiple copies in cellular dna of all domestic cats, a specific fraction was present only in the virus-infected cells. this fraction was detected by viral cdna enriched by a prior absorption of a total complementary dna (cdna) transcript with normal cat liver dna. the recycled cdna hybridized well with the cellular dna of virus-infected cells, but to a lesser extent with dna from uninfected cat cells. the prob ... | 1978 | 210130 |
| potentiation of the neurtalization of feline leukaemia virus in hypotonic medium. | the neutralization of feline leukaemia virus could be enhanced by performing the reaction in hypotonic medium. absorption of antibody by virus specific antigens was also made more sensitive under these conditions. | 1978 | 211186 |
| reiteration frequency of feline type c viral genomes in homologous and heterologous host cell dna. | differences in the multiplicity of proviral sequences of two feline endogenous viruses, rd-114 and felv, in homologous and heterologous host dna were examined by viral cdna hybridization using cellular dna fractionated with respect to reiteration frequency. the endogenous proviral dnas in cat cells were fractionated predominantly with intermediate-repeated sequences, while rd-114 proviral dna in virus-infected human cells was fractionated together with unique-sequence dna. these differences were ... | 1978 | 201591 |
| sarcoma virus-induced transformation specific antigen: presence of antibodies in cats that were naturally exposed to leukemia virus. | 1979 | 88797 | |
| feline sarcoma virus-coded polyprotein: enzymatic cleavage by a type c virus-coded structural protein. | a purified 15,000-molecular-weight (mr) prague strain rous sarcoma virus gag gene-coded structural protein, p15, was shown to enzymatically cleave the previously described 130,000 mr feline sarcoma virus-coded polyprotein, pr130. cleavage products included proteins ranging in molecular weight from 12,000 to 110,000. the specificity of this cleavage reactivity was indicated by the fact that, under similar conditions, neither purified type c viral structural proteins nor nonviral proteins such as ... | 1979 | 219252 |
| [feline leukemia complex]. | 1979 | 230018 | |
| distribution of feline leukemia virus dna sequences in tissues of normal and leukemic domestic cats. | 1979 | 227157 | |
| nature and distribution of feline sarcoma virus nucleotide sequences. | the genomes of three independent isolates of feline sarcoma virus (fesv) were compared by molecular hybridization techniques. using complementary dnas prepared from two strains, sm- and st-fesv, common complementary dna's were selected by sequential hybridization to fesv and feline leukemia virus rnas. these dnas were shown to be highly related among the three independent sarcoma virus isolates. fesv-specific complementary dnas were prepared by selection for hybridization by the homologous fesv ... | 1979 | 225544 |
| hematologic abnormalities preceding myeloid leukemia in three cats. | cytopenia were recognized in three cats infected with feline leukemia virus. in one cat, marrow blast cells were increased in number, and a diagnosis of aleukemic leukemia was made. the disease progressed slowly for 3 1/2 months before terminating in acute myelomonocytic leukemia, recognized as a blast crisis in blood. in the other two cats, neutropenia and altered granulopoiesis in bone marrow preceded development of myeloid leukemia. | 1979 | 289225 |
| biochemical and immunological properties of the dna polymerase and rnaase h activities of purified feline leukemia virus reverse transcriptase. | feline leukemia virus dna polymerase was purified by ion-exchange and nucleic acid affinity chromatographies. the enzyme consists of a single polypeptide chain of mol. wt. approx. 72,000 as determined by both glycerol density gradient centrifugation and sds-polyacrylamide gel electrophoresis. the preferred divalent cation for dna synthesis is mn2+ on a variety of template-primers, and its optimum concentration appears to be significantly lower than reported results of other mammalian type-c vira ... | 1980 | 6159069 |
| feline chronic progressive polyarthritis. | twenty cats with a chronic progressive polyarthritis were studied. the disorder occurred exclusively in male cats, and all but six of the cats were between 1.5 and 5.0 years of age. there were two forms of the disease as determined by radiographic changes: joint instability and deformity, and clinical course. the most prevalent form of the disease was characterized by osteopenia and periosteal new bone formation surrounding affected joints. marginal periarticular erosions and collapse of the joi ... | 1980 | 6250422 |
| feline leukemia. | 1980 | 6251017 | |
| current concepts in veterinary neuro-ophthalmology. | 1980 | 6251595 | |
| in defense of leukoassay f. | 1980 | 6254939 | |
| protection of cats against feline leukemia virus-positive and virus-negative tumors by complement-dependent antibody. | 1980 | 6246303 | |
| shared interspecies antigenic reactivities among hamster and feline oncoviruses. | group-reactive antisera against the major internal protein p30 of the hamster sarcoma virus (hasv) showed interspecies reactivity in immunodiffusion even with sera of low titer against hasv. antisera were prepared by sc injection of virus into male new zealand white rabbits. the cross-reactivity between interspecies antigens of feline and hamster rna tumor viruses was stronger than between either virus with murine leukemia virus. molecular hybridization data, obtained from nucleic acid hybridiza ... | 1981 | 6262550 |
| feline leukemia virus and hepatitis b virus: a comparison of late manifestations. | 1981 | 6262865 | |
| isolation of feline leukemia virus from a leopard cat cell line and search for retrovirus in wild felidae. | a strain of feline leukemia virus (felv), subgroup a, was isolated in early subpassage of a testicular fibroblast culture obtained from a captive asian leopard cat. neither felv nor rd-114 virus was recovered from cultured tissues of 15 other animals, representing eight species of wild felidae. | 1981 | 6268887 |
| a micro-enzyme-linked immunosorbent assay (elisa) test for detection of feline leukemia virus in cats. | 1981 | 6269798 | |
| hematologic abnormalities preceding apparent recovery from feline leukemia virus infection. | a 5-month-old domestic short-haired cat was referred to the western college of veterinary medicine because of hemorrhage from the mouth. neutropenia and bone marrow dyscrasia developed within 2 weeks, and results of a fluorescent antibody test for feline leukemia virus (felv) were positive. during the next 6 months, the feline oncornavirus cell membrane-associated antibody titer increased, the hematologic abnormalities regressed, and the cat became negative to the felv fluorescent antibody test ... | 1981 | 6263848 |
| feline leukaemia virus testing. | 1981 | 6278376 | |
| protection against feline leukemia by vaccination with a subunit vaccine. | an effective vaccine against feline leukemia virus infection has been developed by the collection and concentration of tissue culture medium harvested from a tumor cell line. lymphoid cells were grown to near saturation density in a normal growth medium and then transferred to a serum-free medium. the serum-free medium was collected, concentrated, and evaluated for its vaccine potential. cats receiving the vaccine emulsified in complete freund adjuvant developed high antiviral and antitumor tite ... | 1981 | 6277792 |
| the u3 portion of feline leukemia virus dna identifies horizontally acquired proviruses in leukemic cats. | the presence and location of dna sequences related to the u3 and u5 portions of the infectious exogenous feline leukemia virus (felv) long terminal repeat (ltr) in various cat dnas have been determined by hybridization experiments. in uninfected cat dnas, the u5 ltr segment from the gardner-arnstein strain b virus is present at approximately 150 copies per cell. this level is approximately 10-fold greater than that of endogenous internal felv sequences. the u5 sequences differ in copy number and ... | 1981 | 6278488 |
| epidemiologic association between virus-negative feline leukemia and the horizontally transmitted feline leukemia virus. | about two-thirds of the natural cases of feline leukemia-lymphoma are assumed to be caused by the feline leukemia virus (felv) because they occur in cats, which harbor this agent, and felv will induce the disease under laboratory conditions. epidemiological evidence is presented which associates cases of naturally occurring 'virus negative' feline leukemia with exposure to felv. | 1981 | 6268292 |
| prevalence and sequelae of feline leukemia virus infection in laboratory cats. | over a 4-year period, 1,683 pound-source cats received at a research institution were screened for feline leukemia virus (felv) infection, using an indirect fluorescent antibody test. viremia was detected in 83 of the cats, for a prevalence of 4.9%. during this period, felv infection was detected in 5 kittens on a research project; lymphoma or anemia developed 6 to 17 months after the infections were detected. it was concluded that apparently healthy cats infected with felv may not be appropriat ... | 1981 | 6276347 |