Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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endocrinopathy in mice affected with scrapie. | 1972 | 4506200 | |
electron microscopic studies of the brain of sheep with natural scrapie. i. the fine structure of neuronal vacuolation. | 1972 | 4676242 | |
[visna-maedi in a flock of merino sheep in lower franconia]. | 1972 | 4551099 | |
[sheep pruritus (scrapie). review of the foreign literature]. | 1972 | 4571552 | |
interspecies patterns of slow virus diseases. | 1972 | 4577378 | |
the effect of concurrent scrapie on louping-ill encephalitis in the mouse. | 1972 | 4556469 | |
animal model of human disease: kuru, creutzfeldt-jakob disease (slow virus infections). animal model: transmissible mink encephalopathy, scrapie-like disease of mink. | 1972 | 4562796 | |
rapid diagnosis of scrapie in the mouse. | 1972 | 4564815 | |
[creutzfeldt-jakob disease and its transmission]. | 1972 | 4567162 | |
demyelinating diseases and certain virus infections. | 1972 | 4359244 | |
scrapie-induced changes in the percentage of polymorphonuclear neutrophils in mouse peripheral blood. | a decrease in the percentage of polymorphonuclear neutrophils (pmn) in the peripheral blood of mice appeared 3 days after intracerebral (ic) inoculation with scrapie mouse brain homogenate. mice inoculated ic with normal mouse brain had pmn percentages similar to those found for uninoculated mice. this difference between normal and scrapie-inoculated mice continued throughout the preclinical phase of the disease. in the clinical phase of the disease, the percentage of pmn was either higher or lo ... | 1972 | 4118048 |
failure of the scrapie agent to replicate in l5178y mouse leukaemic cells. | 1972 | 4336055 | |
periodate--an inhibitor of the scrapie agent? | 1972 | 4338602 | |
action of an alcoholic solution of iodine on the scrapie agent. | 1972 | 4338603 | |
virus-like particles in natural scrapie of the sheep. | 1973 | 4196559 | |
viral infections and demyelinating diseases. | 1973 | 4348989 | |
comparative studies on visna, progressive pneumonia, and rous sarcoma viruses by electron microscopy. | 1973 | 4349766 | |
experimental subacute spongiform virus encephalopathies in primates and other laboratory animals. | the host range of subacute spongiform virus encephalopathies is described. the asymptomatic incubation period and the duration of the illnesses in various species of animal hosts is discussed along with information on additional species of old world and new world monkeys and the domestic cat, which have been shown to be susceptible to subacute spongiform virus encephalopathies. | 1973 | 4199733 |
a new hypothalamic pathway to the median eminence containing neurophysin and its hypertrophy in sheep with natural scrapie. | 1973 | 4571633 | |
failure to demonstrate a humoral immune response to scrapie infection in mice. | 1973 | 4200779 | |
similarities between the scrapie agent and the agent of the potato spindle tuber disease. | 1973 | 4209370 | |
altered response to scrapie tissues in neurological disease. possible evidence for an antigen associated with reactive astrocytes. | 1973 | 4200639 | |
rapid immunological method for diagnosis of natural scrapie in sheep. | 1973 | 4583489 | |
scrapie-like antigen(s) in ageing tissues. | 1973 | 4583502 | |
aberrant synaptic development. | 1973 | 4573665 | |
[viral infections and chronic central nervous system diseases]. | 1973 | 4347158 | |
unsuccessful attempts to produce disease with tissues from mice fed on a diet containing cuprizone. | 1973 | 4736048 | |
the distribution of vasopressin and neurophysin in the hypothalamo-distal-neurohypophysial and hypothalamo-infundibular neurosecretory systems of normal and scrapie-affected sheep. | 1973 | 4573917 | |
implications of slow viral diseases of domestic animals for human disease. | 1973 | 4578994 | |
[slow viruses and the central nervous system. i]. | 1973 | 4579465 | |
developmental maturation of susceptibility to scrapie in mice. | 1973 | 4632780 | |
emergence of new antigens in ageing tissues. | 1973 | 4129994 | |
viral and non-viral properties of the scrapie agent. | 1973 | 4209651 | |
[creutzfeldt-jakob's disease. a human spongiform viral encephalopathy]. | 1973 | 4196163 | |
differences in access into the central nervous system of me7 scrapie agent from two strains of mice. | 1973 | 4199906 | |
scrapie in mice. some effects on the brain lesion profile of me7 agent due to genotype of donor, route of injection and genotype of recipient. | 1973 | 4199907 | |
scrapie in mice. agent-strain differences in the distribution and intensity of grey matter vacuolation. | 1973 | 4199908 | |
immunological reactions in scrapie: the basis of a rapid titration method. | 1973 | 4204065 | |
[latest achievements in the study of subacute spongious encephalopathies]. | 1973 | 4204259 | |
transmissible mink encephalopathy: studies on the peripheral lymphocyte. | circulating lymphocytes from mink with transmissible mink encephalopathy were studied for the presence of virus particles and for infectivity. electron microscope examination of phytohemagglutinin-stimulated lymphocyte cultures revealed no evidence of virus-like particles. circulating lymphocytes were also found to be noninfectious when the transmissible agent could be demonstrated in intact lymphoid organs in infected mink. a lymphopenia was detected in affected mink during the late clinical st ... | 1973 | 4197388 |
multiplicity of scrapie virus in infected mouse spleen cells in vivo. | subpopulations of spleen cells from scrapie virus-infected mice were used to determine the average virus content of infected cells in vivo at a time when virus was rapidly increasing in titer in lymphoreticular tissues. comparison of the mean lethal doses of lysed to intact cells indicated averages of 2 to 6 infectious units per infected cell. in another experiment, preparations of cytoplasmic nucleic acids extracted from spleen cells of infected mice had no detectable infectivity, which suggest ... | 1973 | 4197750 |
ultrastructural observations on scrapie in the gerbil. | 1973 | 4209188 | |
[disseminated sclerosis and slow virus diseases (author's transl)]. | 1973 | 4127809 | |
argyrophilic plaques in mice inoculated with scrapie from particular sources. | 1973 | 4120692 | |
inhibition of rna slow viruses by thiosemicarbazones. | 1973 | 4122206 | |
higher frequency of a protein band in the cerebrospinal fluid from scrapie mice. | 1973 | 4141787 | |
animal health. | 1973 | 4148822 | |
clinical and histological recovery from the scrapie-like spongiform encephalopathy produced in mice by feeding them with cuprizone. | 1973 | 4737068 | |
permeability of blood vessels in mice affected with scrapie or fed with cuprizone. | 1973 | 4797843 | |
thymectomy and immunological ageing in mice: precocious emergence of scrapie-like antigen. | 1973 | 4798070 | |
a report of scrapie in sheep in kenya. | 1973 | 4731572 | |
glycosidases in normal and scrapie mouse brain. | 1973 | 4735407 | |
replication of the factor in scrapie material that causes a decrease in polymorphonuclear neutrophils. | 1973 | 4737373 | |
a cytological study of the karyotype of spleen cells from scrapie-affected chinese hamsters. | 1973 | 4738622 | |
an attempt to induce scrapie in local sheep in bulgaria. | 1973 | 4779441 | |
glycoprotein biosynthesis in normal and scrapie-affected mouse brain. | 1973 | 4796893 | |
[slow viruses and cns. ii]. | 1973 | 4582184 | |
scrapie in sheep selectively bred for high susceptibility. | 1974 | 4824026 | |
a comparison of the biochemical changes induced in mouse brain cuprizone toxicity and by scrapie infection. | 1974 | 4859191 | |
the turnover of isotopically labelled dna in vivo in developing, adult and scrapie-affected mouse brain. | 1974 | 4859554 | |
an electron microscopic study of the scrapie mouse and rat: further observations on virus-like particles with ruthenium red and lanthanum nitrate as a possible trace and negative stain. | 1974 | 4141754 | |
a rapid immunologic test for scrapie in sheep. | 1974 | 4132111 | |
course of experimental scrapie virus infection in the goat. | 1974 | 4207308 | |
depression of polymorph counts by various scrapie agents. | 1974 | 4207411 | |
scrapie and transmissible mink encephalopathy: search for infectious nucleic acid. | brain preparations from animals with scrapie or transmissible mink encephalopathy were phenol extracted and examined for the presence of pathogenic nucleic acid. animals inoculated with various extracts remained healthy, and analysis on 2.6 to 5% polyacrylamide gels failed to detect a difference in extractable rna species between infected and normal mink brain. | 1974 | 4207527 |
reduced susceptibility to scrapie in mice after steroid administration. | 1974 | 4209742 | |
slow virus diseases of the central nervous system. | 1974 | 4213582 | |
scrapie. | 1974 | 4214256 | |
ultrastructural studies of spleens, brains, and brain cell cultures of mice with scrapie. | 1974 | 4215206 | |
ruthenium red and lanthanum nitrate a possible tracer and negative stain for scrapie "particles"? | 1974 | 4140674 | |
editorial: kuru, creutzfeldt-jakob, and scrapie. | 1974 | 4140986 | |
naturally-occurring scrapie in goats. | 1974 | 4859427 | |
glycosyl transferase activity in normal and scrapie-affected mouse brain. | 1974 | 4212037 | |
scrapie: observations on a field outbreak. | 1974 | 4836096 | |
pathology of choroid plexus in spontaneous immune complex disease and chronic viral infections. | 1974 | 4276256 | |
[visna virus-like particles in cultures of choroid plexus cells of a goat with symptoms of visna infection]. | 1974 | 4363195 | |
nature of the scrapie agent: evidence against a viroid. | the postulated viroid nature of scrapie agent was tested. since the agent could not be recovered after a carefully controlled phenol extraction of infected mouse brains, it is suggested that this agent is not a viroid. | 1974 | 4372389 |
slow virus diseases. | 1974 | 4372938 | |
further observations on the production of scrapie in sheep by oral dosing with foetal membranes from scrapie-affected sheep. | 1974 | 4425935 | |
an electron microscopic study of natural scrapie sheep brain: further observations on virus-like particles and paramyxovirus-like tubules. | 1974 | 4446935 | |
no mouse pmn leukocyte depression after inoculation with brain tissue from multiple sclerosis or spongiform encephalopathies. | 1974 | 4589575 | |
comparative scrapie activity of brain material and cerebrospinal fluid from scrapie-affected rats. | 1974 | 4210058 | |
maternal and lateral transmission of scrapie in sheep. | 1974 | 4212154 | |
letter: scrapie. | 1974 | 4213860 | |
slow infections of the nervous system and the subacute spongiform encephalopathies. | 1974 | 4374882 | |
letter: interspecies transmission of scrapie-like diseases. | 1975 | 54832 | |
slow encephalopathies, inflammatory responses and arachis oil. | there is much interest in the possibility that diets rich in some plant oils may be of prophylactic and curative value in certain clinical conditions. this is generally attributed to the immunosuppressive effects of polyunsaturated fatty acids. arachis (peanut) oil injections can increase the incubation period of experimental scrapie in mice. in the late 1950s several workers showed that arachis and some other oils contained very potent anti-inflammatory components quite apart from the polyunsat ... | 1975 | 47424 |
persistent or slow viral infections and related diseases. | the discovery of persistent transmissible agents by veterinarians has led to striking advances in the infectious cause of neuropathies of human beings. there is evidence for persisting infection in congenital rubella and the herpes group of viruses including cytomegalovirus infections. hepatitis types a and b are candidates for inclusion in the category of persisting viral infections. the rubeola or measles virus is established as a persistent virus which causes elevated antibodies in the serum ... | 1975 | 165638 |
newer knowledge in comparative virology--its contribution to human health research. | like other comparative sciences, and despite its recent beginning comparative virology has already contributed useful applications and observations to human health research. teachings derived from the study of marek's disease found application in that of burkitt's lymphoma, and may lead to a possible vaccine against the human disease. equally useful information came from the study of canine distemper in the development of a chorio-allantoic membrane attenuated measles vaccine, and in our knowled ... | 1975 | 167504 |
our present knowledge of the pathology of dementias. | 1975 | 172773 | |
familial and sporadic chronic neurological degenerative disorders transmitted from man to primates. | 1975 | 125030 | |
recent data on the properties of the viruses of kuru and transmissible virus dementias. | 1975 | 134597 | |
the occurrence of vacuolated neurons in the brains of hamsters affected with subacute sclerosing encephalitis following measles or langat virus infection. | hamsters infected by the intranasal route with either hamster adapted langat virus passaged at least 10 times in hamsters and the hnt strain of measles virus passaged 149 times in hamsters, developed subacute sclerotic lesions in the pyriform cortex, and beginning from 2 months after infection, were accompanied by neuronal vacuolation with ballooning of the cytoplasm, especially in parts of the brain in close proximity of the sclerotic lesions. the vacuolated neurons resembled those seen in scra ... | 1975 | 173381 |
pathology of dendrites in subacute spongiform virus encephalopathies. | the spongiform changes in the cerebral cortex of scrapie mice and of chimpanzees afflicted with experimental kuru and creutzfeldt-jakob disease were examined by electron microscopy. the pathognomonic findings consisted of swelling and vacuolation of neurons, particularly of dendrites. fusion of swollen cells and processes occurred. the changes were associated with alterations of plasma membranes. curled fragments of membranes accumulated at points of cell fusion and at the margin of vacuoles wit ... | 1975 | 1098420 |
[case of scrapie in a goat]. | 1975 | 1168094 | |
multiple sclerosis: relation to scrapie and slow infection; ageing and measles. | multiple sclerosis (ms) is shown to have no relation to scrapie and the evidence for a "slow infective" aetiology is very meagre. it is not related to an ageing process during which scrapie-like antigens make their appearance as they do in young animal with the disease. the emergence of scrapie-like antigens in ageing tissues is discussed. the increased sensitization of ms lymphocytes to scrapie, as opposed to normal brain (or spleen), is not characteristic of the disease, but occurs in other co ... | 1975 | 1217459 |
infectious etiology of neuritic (senile) plaques in mice. | brains of inbred female vm mice infected with scrapie agent were studied with the use of the bodian silver impregnation method and by electron microscopy. in brains affected with scrapie, after an incubation period of between 587 and 655 days, numerous primitive, classical, and amyloid plaques were found. no plaques of any type were seen in the control mice. | 1975 | 1237933 |
[discovery of viroids and possible relationship with human and veterinary medicine]. | the researches of diener and co-workers and those of the semancik's group, have recently established that some plant diseases, such as potato spindle tuber, citrus exocortis disease and chrysanthemum stunt, are caused by a new class of pathogens, named viroids. these are the smallest known agents (they are smaller than viruses) having a molecular weight of ca 10(5) daltons, and composed of a highly structured rna, rich in guanine-cytosine base pairs without a capsid. little is known about the or ... | 1975 | 132907 |
isolation of 14-nm virus-like particles from mouse brain infected with scrapie agent. | 1975 | 810725 | |
the establishment of sheep flocks of predictable susceptibility to expirimental scrapie. | a selection experiment, based on a foundation stock of over 700 herdwick sheep and aimed at producing divergent populations of predictable high susceptibility or resistance to experimental scrapie was begun at this institute in 1961. twelve years later, flocks of presumed 100 per cent susceptibility to the cheviot-dervied scrapie agent ssbp-1 used throughout the experiment, and also manifesting a high incidence of the disease when challenged with other scrapie strains, are used in the compton sc ... | 1975 | 804177 |