| fatal granulomatous angiitis of the nervous system confined to the middle cerebral artery--a post mortem evaluation. | | 2009 | 2747479 |
| acute pseudobulbar palsy due to bilateral focal cortical damage: the opercular syndrome of foix-chavany-marie. | two children are described who suddenly developed an encephalitic illness with intractable bilateral facial seizures. the seizures subsided over several days, but the children were left with the signs of pseudobulbar palsy and are unable to speak or swallow effectively. bilateral destructive lesions in the opercular regions evolved on computed tomographic scans. both children were treated with acyclovir relatively early in the illness, and cerebrospinal fluid and serum antibodies support the dia ... | 2009 | 2715610 |
| [radioimmunologic analysis of insulin (iri) in glucose metabolism in uremic patients]. | glucose intolerance in uremic patients is often reported in literature. this condition is characterized by an unbalance between production and utilization of glucose as for a trouble of the mechanism of gluco-metabolic regulation. insulin radioimmunoassay (iri) is measured to know the amount of hormone incretion and to verify its efficacy in the glucose utilization. the glucagon load and the double glucagon load are tests employed to study iri response and glucose metabolism in uremia. with the ... | 2009 | 2701029 |
| airway responsiveness in infancy. | | 2009 | 2889415 |
| electron microscopy for the rapid detection and identification of viruses from clinical specimens. | the advantages of using electron microscopy for rapid diagnosis of virus infection from clinical specimens, for identification of virus isolates with unusual properties, and for monitoring endogenous agents in cell cultures are illustrated by several actual cases that have occurred over the years. the importance of using morphological characteristics of viruses for initial identification is emphasized. | 2009 | 2672617 |
| torsion--treatment indications. | rotational problems, when outside the normal range, are referred to as torsional deformity. these deformities are relatively common in infancy and childhood, generally resolve spontaneously with growth, and rarely persist into adult life. there are few situations in which treatment is necessary. (1) rigid metatarsus adductus that does not resolve during the first six months should be corrected by casting. the long leg cast is most effective, as it controls the rotation of the tibia. with the tib ... | 2009 | 2676305 |
| response patterns of purified myeloma cells to hematopoietic growth factors. | tumor cells were isolated from the bone marrow of seven patients with multiple myeloma and from the peripheral blood of three patients with plasma cell leukemia using ficoll-hypaque (fh) density sedimentation followed by immune rosette depletion of t, myeloid, monocytoid, and natural killer (nk) cells. enrichment to greater than or equal to 93% plasma cells was confirmed with wright's-giemsa staining, with intracytoplasmic immunoglobulin staining, and with staining using monoclonal antibodies (m ... | 2009 | 2713508 |
| [some definitions for better understanding of piezography]. | | 2009 | 2698392 |
| chiasmal compression caused by a catheter in the suprasellar cistern. | | 2009 | 3285696 |
| a french research programme: santé-maladie-société (1984-1988). | | 2009 | 2662421 |
| [sarcoidosis]. | sarcoidosis seldom occurs in children. the illness has variable clinical manifestations. diagnosis is often delayed because of the variable clinical manifestations and the sporadic occurrence. the case history of one patient is described. the presentation, diagnostical approach. therapy and course of sarcoidosis is discussed. | 2009 | 2741158 |
| adolescents and alcohol--a review of the recent british research. | there is evidence of increased alcohol consumption by young people. this review concentrates on the british epidemiological and psychological studies of adolescent drinking behaviour, with special reference to the cultural and developmental aspects. it is clear that drinking alcohol may be considered a normal part of adolescence and many young people are introduced to it by their parents. however, one area of concern is the amount of drunkenness reported. the way forward is to gain new insights ... | 2009 | 2687340 |
| captopril test in screening hypertensive patients. | | 2009 | 2666599 |
| sonographic and pathological staging of patients with clinically localized prostate cancer. | we evaluated 64 patients with clinically localized prostate cancer (on the basis of rectal examination, serum acid phosphatase, bone scan and pelvic computerized tomography scan) by transrectal sonography before radical prostatectomy. of the 48 patients with histologically proved localized prostate cancer sonography overstaged the disease in 5 (10%) and correctly staged it in 43 (90%). all overstaged cancer patients were scanned after either prostatic biopsy (4) or transurethral prostatectomy (1 ... | 2009 | 2681836 |
| regulation of plasminogen activators and their inhibitors in rheumatic diseases: new understanding and the potential for new directions. | over the past several years there has been a rapid expansion in our understanding of the fibrinolytic system. this includes knowledge of the components, availability of recombinant reagents and a better understanding of the regulation of fibrinolysis in health and disease. disturbances in the regulation of the balance between fibrin deposition and removal have been implicated in a number of inflammatory diseases including certain rheumatic diseases. this overview summarizes our knowledge of the ... | 2009 | 2681762 |
| italian survey on allogeneic bmt for chronic myeloid leukaemia. | | 2009 | 2697445 |
| applications of immunocytochemistry to diagnostic cytopathology. | immunohistochemical technique is now successfully applied to the cytologic materials. this review article describes details of staining procedures for immunocytochemistry at both light and electron microscopic levels. the clinical application of the technique includes aspiration biopsy cytology for breast lesions, thyroid lesions, lymph nodes, the nervous system, and others. the establishment of carcinoma cells in the body fluid by the demonstration of carcinoembyronic antigen (cea) and the esta ... | 2009 | 2656146 |
| cutaneous histiocytosis syndromes. | cutaneous histiocytosis may take two principal forms. it is either a benign proliferative process or a relentless, progressive process with a poor prognosis. in histiocytic medullary reticulosis, histiocytes demonstrate nuclear atypia and the outcome is uniformly fatal. benign cephalic histiocytosis x causes lesions similar to those of histiocytosis x, but langerhans' cells are absent. in congenital self-healing histiocytosis x, the letterer-siwe-like cutaneous infiltrate contains langerhans' ce ... | 2009 | 2999740 |
| [biliary peritonitis after hepatic biopsy: favorable course with conservative medical treatment]. | in a 53-year-old woman a percutaneous liver biopsy was performed with tru-cut to study persistent hypertransaminasemia. the patient did not present extrahepatic cholestasis. immediately after biopsy the patient had a picture of biliary peritonitis that evolved favorably with conservative medical treatment, including hemodynamic resuscitation, antibiotic therapy, analgesic treatment and monitoring by the resuscitation service. a review is made of the literature on this complication of liver biops ... | 2009 | 2660206 |
| [primary and secondary neoplasms of the salivary glands in the province of trieste (1977-1986). histopathological review and epidemiological picture of 151 cases]. | the authors carried out a histopathological and epidemiological study on 151 cases of primary and secondary neoplasms of the salivary glands. the parotid gland was involved in 117 cases (78.5%). the tumours were malignant in 20% (30 cases) of the lesions. the most common neoplasms were pleomorphic adenoma (74 cases) and adenolymphoma (35 cases). the occurrence of the latter were, for both sexes, directly correlated to the age of the subjects. the malignant neoplasms were also in direct relation ... | 2009 | 2626276 |
| 3c syndrome: third occurrence of cranio-cerebello-cardiac dysplasia (ritscher-schinzel syndrome). | we report a child with an unusual pattern of malformations: severe delay in bone maturation, wide fontanelles and facial dysmorphism (evoking cleidocranial dysplasia), relative macroencephaly with cerebellar vermis hypoplasia, hypertelorism, skeletal abnormalities (1st ribs aplasia, multifocal sternal ossification centers, thin bones), septal defect, muscular waste, hypotonia and developmental delay. most of these features have been reported previously by ritscher, schinzel et al. in two sibs, w ... | 2009 | 2650935 |
| nonsteroidal anti-inflammatory drugs, and hypertension. | | 2009 | 3293496 |
| [that's what i remember best: night shift 4 weeks on end]. | | 2010 | 3551170 |
| [that's what i remember best: night shift 4 weeks on end]. | | 2010 | 3551170 |
| cloxacillin-induced neutropenia. | | 2010 | 3722871 |
| the adenosine triphosphate-pyrophosphate isotopic exchange reaction: a tool for determination of tryptophan. | quantitative determination of tryptophan at the picomole level is described, using the atp-[32p]ppi isotopic exchange reaction catalyzed by tryptophanyl-trna synthetase. sensitivity limits of 500 fmol were obtained. the presence of other amino acids at a 1000-fold excess over tryptophan did not interfere significantly with the quantitative determination of tryptophan. the specificity of the reaction was checked using five tryptophan analogs. these analogs did not prevent the determination of try ... | 2010 | 3014918 |
| anti-immunoglobulin and phorbol ester induce phosphorylation of proteins associated with the plasma membrane and cytoskeleton in murine b lymphocytes. | protein phosphorylations are rapidly induced in intact b cells by antibodies to surface immunoglobulin (anti-igm) and by phorbol 12-myristate 13-acetate (pma). a comparison of the molecular weight, isoelectric points, phosphopeptides, and phosphoamino acids of the phosphoproteins induced by anti-igm and by pma suggests that anti-igm acts through the activation of protein kinase c. this conclusion is strengthened by the observation that prolonged treatment with pma ablates the ability of anti-igm ... | 2010 | 3021753 |
| anti-immunoglobulin and phorbol ester induce phosphorylation of proteins associated with the plasma membrane and cytoskeleton in murine b lymphocytes. | protein phosphorylations are rapidly induced in intact b cells by antibodies to surface immunoglobulin (anti-igm) and by phorbol 12-myristate 13-acetate (pma). a comparison of the molecular weight, isoelectric points, phosphopeptides, and phosphoamino acids of the phosphoproteins induced by anti-igm and by pma suggests that anti-igm acts through the activation of protein kinase c. this conclusion is strengthened by the observation that prolonged treatment with pma ablates the ability of anti-igm ... | 2010 | 3021753 |
| interest of the dosage of the h.c.g. in the spermatical blood at the moment of the castration for a testicular tumor (about 28 cases 1978-1984). | | 2010 | 3008177 |
| epidemiology of borderline ovarian tumors. | ovarian tumors of low malignant potential, often termed "borderline tumors," have been defined as those that have some but not all of the morphologic features of malignancy (i.e., they are not invasive). with the use of data obtained by the western washington population-based cancer surveillance system for 1975-83, the incidence of serous and mucinous borderline epithelial ovarian tumors was analyzed, as well as the survival of women who developed them. the incidence of borderline tumors increas ... | 2010 | 3025504 |
| epidemiology of borderline ovarian tumors. | ovarian tumors of low malignant potential, often termed "borderline tumors," have been defined as those that have some but not all of the morphologic features of malignancy (i.e., they are not invasive). with the use of data obtained by the western washington population-based cancer surveillance system for 1975-83, the incidence of serous and mucinous borderline epithelial ovarian tumors was analyzed, as well as the survival of women who developed them. the incidence of borderline tumors increas ... | 2010 | 3025504 |
| [role of laparoscopic examination in the diagnosis and control of treatment results in early and less advanced forms of endometriosis]. | | 2010 | 2956633 |
| [computed tomographic determination of thyroid iodine concentration in an endemic goiter area]. | we determined the ct density of the thyroid gland in 60 patients with normal thyroids and 176 patients with various thyroid disorders. the density was 75 +/- 6.2 h.u. in normal thyroids, which was markedly higher than in goiters (66 +/- 6.0 h.u.), while there was a considerable further decrease in patients with immunogenic hyperthyroidism, the density being 48.5 +/- 7.9 h.u. the thyroids of patients with nonimmunogenic hyperthyroidism differed from these by virtue of a significantly greater dens ... | 2010 | 3008254 |
| brain beta-endorphin and spinal-cord enkephalin concentrations in experimental arachnoiditis. | arachnoiditis was produced experimentally in male albino icr mice by intrathecal injection of meglumine iocarmate . a control group received intrathecal injection of an electrolyte solution resembling csf. eight weeks after injection, the brains and spinal cords were removed for brain beta-endorphin and spinal cord met-enkephalin measurement by radioimmunoassay, and the dural sacs were removed for histologic examination to confirm the presence or absence of arachnoiditis. brain beta-endorphin co ... | 2010 | 2951348 |
| relationship among function, phenotype, and specificity in primary allospecific t cell populations: identification of phenotypically identical but functionally distinct primary t cell subsets that differ in their recognition of mhc class i and class ii allodeterminants. | the goal of the present study was to evaluate the relationship among function, lyt phenotype, and mhc recognition specificity in primary allospecific t cell populations. by using lyt-2+ and l3t4+ t cells obtained from the same responder populations, we assessed the ability of t cells of each phenotype to generate cytotoxic effector cells (ctl) and il 2-secreting helper t cells in response to either class i or class ii mhc allodeterminants. it was found that a discordance between lyt phenotype an ... | 2010 | 2946773 |
| percutaneous transluminal angioplasty improves blood pressure and renal function in renovascular hypertension. | thirty-three patients with renal angiographic evidence of significant renal artery stenosis were referred for percutaneous transluminal angioplasty. the indications were poorly controlled hypertension (n = 13) or hypertension associated with deteriorating renal function (n = 20). their mean age was 56 (23-73) years (12 males, 21 females). causes of the renal artery stenosis were fibromuscular dysplasia (n = 8) and atheromatous changes (n = 25). four patients were excluded, three due to technical ... | 2010 | 2958895 |
| surgical streams in the flow of health care financing. the role of surgery in national expenditures: what costs are controllable? | the dollar flow in united states medical care has been analyzed in terms of a six-level model; this model and the gross 1981 flow data are set forth. of the estimated $310 billion expended in 1981, it is estimated that $85-$95 billion was the "surgical stream", i.e., that amount expended to take care of surgical patients at a variety of institutional types and including ambulatory care and surgeons' fees. some of the determinants of surgical flow are reviewed as well as controllable costs and ca ... | 2010 | 3918514 |
| chronic renal disease and hyperparathyroidism: dental manifestations and management. | | 2010 | 2963695 |
| [treatment of chronic renal failure with traditional chinese medicine. follow-up of 90 cases]. | | 2010 | 2947714 |
| abnormal degradation of erythrocyte membrane proteins in down's syndrome. | | 2010 | 2953697 |
| [changes in metabolic control after interruption of oral hypoglycemic agents in type ii diabetic patients with secondary failure during combined therapy]. | | 2010 | 2976347 |
| [experimental study of oral administration of streptococcal preparation "ok-432". the 6th report: its effect on in vivo anti-tumor immunity of the mice with transplanted cecal tumor]. | | 2010 | 2932509 |
| calcific shoulder periarthritis (tendinitis) in adult onset diabetes mellitus: a controlled study. | two groups, one of 824 adult diabetics and one of 320 age and sex matched non-diabetics, were examined for abnormal glucose metabolism and calcifications on anteroposterior shoulder x rays. two hundred and sixty two (31.8%) of the diabetics had shoulder calcification compared with 33 (10.3%) of the control group, with a preponderant localisation in the right shoulder. diabetes of long duration treated with insulin for a long time was associated with a larger percentage of shoulder calcifications ... | 2010 | 2930276 |
| right atrial cardioplegia: a safe procedure for myocardial protection. | | 2010 | 2919927 |
| [fibrinolytic therapy of thromboembolic vascular occlusions: experiences based on 87 patients]. | | 2010 | 2974192 |
| [immunologic functions of kupffer cells]. | | 2010 | 2937390 |
| ciprostene in patients with peripheral vascular disease (pvd). an open-label, tolerance trial. | epoprostenol (prostacyclin) has been studied with various success in patients with peripheral vascular disease (pvd). we investigated the tolerance of a new, stable prostacyclin derivative ciprostene (9-beta-methyl carbacyclin) in 9 pvd patients. the drug was infused intravenously for 8 hours a day, once a week for 4 consecutive weeks, at a dose of 120 ng/kg/min. there were 6 men and 3 women with a mean age of 63 years (42-78). the pvd was verified by arteriography (9 patients) and by clinical f ... | 2010 | 3068680 |
| cocaine--the deadliest addiction. | | 2010 | 2911405 |
| [genetic counseling in ornithine carbamoyltransferase deficiency]. | ornithine transcarbamylase (otc) deficiency is an inborn error of urea cycle metabolism, responsible for lethal hyperammonemia in males and for severe symptoms in at least 20% of heterozygous females. the authors provide here additional data on the informativity of the protein loading test (plt) for the detection of heterozygotes. they show that the risk of being a carrier for the mother of an affected boy falls from 2/3 a priori to only 1/8 if her plt is negative. the risk for the mother of het ... | 2010 | 2903704 |
| sex therapy for the penile prosthesis recipient. | in conclusion, the evidence for technical success of the penile prosthesis is clear, but more detailed follow-up studies suggest that a large minority of patients and partners fail to achieve sexual satisfaction. if the goal of surgery is to restore sexual frequency, variety, and pleasure to optimal levels, an integrated treatment program that incorporates sex therapy may be more successful than implantation alone. the type of sex therapy required depends on the risk factors present for postsurg ... | 2010 | 2916282 |
| carrier detection of haemophilia a using dna markers in families with an isolated affected male. | the carrier status of women in five families with an isolated haemophilia male was assessed by pedigree analysis, coagulation factor assays and dna markers. in three families, ten women could be given very low risks of being carriers based on dna analysis. in two of the families the dna markers identified the mutation as originating in either the maternal or maternal grandfather's germ cell. combined dna and coagulation data suggested that the affected male in a third family was a de novo mutati ... | 2010 | 2887317 |
| clinical experience with controlled expansion cylinders. the ams 700 cx inflatable penile prosthesis. | device manufacturers continue to look for modifications in design to achieve specific objectives directed at improving overall reliability. changes in design that do not address this extremely significant concern, namely, device reliability, fail in their commitment toward improvement in patient satisfaction. one of the most effective ways to assess the benefits provided by any change in device design is through the clinical trial and study group method, utilizing a large number of implanting su ... | 2010 | 2916279 |
| the artificial sphincter (as-800). experience in children and young adults. | from reviewing our experience in the application of the as-800 sphincter for the management of incontinence in children, we conclude that implantation is indicated after conservative and less invasive therapy has been attempted. the bladder neck is the site of choice for cuff placement in children. primary deactivation and moderate or low reservoir pressures (61 to 70 and 71 to 80 cm h2o) are indicated, especially in patients with previous bladder neck surgery or an inadvertent bladder neck inju ... | 2010 | 2916269 |
| coexistence of egg-laying hormone and alpha-bag cell peptide in bag cell neurons of aplysia indicates that they are a peptidergic multitransmitter system. | double-label immunocytochemistry reveals that immunoreactivity for two putative peptide transmitters, egg-laying hormone and alpha-bag cell peptide, co-exist in most bag cell somata and processes in the abdominal ganglion of the marine mollusc aplysia. together with previous physiological and biochemical data these findings indicate that the neuroendocrine bag cells are a multitransmitter system which utilizes two or more peptides derived from a common precursor. | 2010 | 2877421 |
| antagonism of vecuronium and atracurium: comparison of neostigmine and edrophonium administered at 5% twitch height recovery. | in 39 healthy patients antagonism, by neostigmine 0.07 mg kg-1 or edrophonium 0.8 mg kg-1, of neuromuscular blockade induced by vecuronium or atracurium, was compared. reversal was attempted when the height of the single twitch (th) had recovered spontaneously to 5% of the control value. the evoked responses, initially single twitch, then train-of-four (tof) were observed until the tof ratio was 70%. induced recovery from th 5% to 25% was shorter following edrophonium than following neostigmine ... | 2010 | 2882769 |
| chemotactic function of polymorphonuclear leukocytes from patients with recurrent infections: partial correction by levamisole "in vitro". | polymorphonuclear leukocytes are dominant cells in the defense of the organism, and their functional alterations result in increased risks of infection. chemotaxis is an early function in the immune response, allowing for the polymorphonuclear cells to migrate towards inflammatory sites. we studied the chemotactic function of the polymorphonuclear leukocytes from 14 patients with the common clinical syndrome of recurrent infections, through a technique of cell migration under agarose. it was fou ... | 2010 | 4003229 |
| magnetic resonance imaging and early diagnosis of multiple sclerosis. | | 2010 | 2903418 |
| blood coagulability and viper envenomation. | | 2010 | 2869321 |
| psychosocial and physiological factors in relation to blood pressure at rest--a study of swedish men in their upper twenties. | the interrelationships between psychosocial factors, several physiological variables and blood pressure (bp) were investigated in 88 young men (aged 26-32 years) in whom high, intermediate or low bp had been recorded at the age of 18 years. in the original high bp group, venous plasma noradrenaline was normal but adrenaline levels elevated. at the follow-up adrenaline correlated with systolic blood pressure (sbp), and this was also so after controlling for overweight and serum gamma-glutamyltran ... | 2010 | 2868055 |
| selective adrenergic beta-2-receptor blocking drug, ici-118.551, is effective in essential tremor. | eighteen patients with essential tremor were treated for 2 days with a non-selective adrenergic beta-blocking drug (dl-propranolol, 80 mg x 3), a beta-2-selective blocker (ici-118.551, 50 mg x 3) and placebo (x 3) in a randomized double blind cross-over study. postural hand tremor was recorded with an accelerometer before administration of the drugs and at the end of each treatment period. compared with placebo, both the beta-blocking drugs caused a statistically significant decrease in tremor i ... | 2010 | 2876576 |
| quantitative evaluation of leukemic mitochondria with a computer-controlled image analyzer. | mitochondria from 25 patients with acute lymphoblastic leukemia (all) and 25 patients with acute myelogenous leukemia (aml) were compared in terms of their number, area, and shape index using a computer-controlled image analyzer. the number of mitochondria was greater in the aml than in the all patients. however, their size, as measured in electron micrographic profiles was similar in the two groups, in disagreement with conventional reports that mitochondria are small in granulocytes but large ... | 2010 | 2876544 |
| [partial 21-hydroxylase deficiency: study of 5 cases]. | | 2010 | 2845201 |
| exposure to benzodiazepines in utero. | | 2010 | 2884529 |
| somatostatin analogue sms 201-995 in type i diabetes mellitus. initial experience after repeated administration. | we have recently obtained encouraging short-term results after a single subcutaneous injection of the long-acting somatostatin analogue sms 201-995 in acromegalic patients. increased growth hormone (gh) levels may be involved in the pathogenesis of proliferative retinopathy in type i diabetes mellitus. in this study we thus investigated the effect of 3 x 50 micrograms sms 201-995 daily on the metabolic control and hormone secretion of eight type i diabetics over a 3-day period. gh levels decreas ... | 2010 | 2876502 |
| the effects of a supratentorial mass lesion on brain-stem auditory evoked potentials and short latency somatosensory evoked potentials. | nineteen patients with unilateral supratentorial mass lesion and without any evident clinical signs of transtentorial herniation were studied with computed tomography (ct), brain-stem evoked potentials (baeps) and central conduction time (cct) of short latency somatosensory evoked potentials (seps). sixteen had tumours, two had intracranial haematoma and one had chronic subdural haematoma. ct detected the initial signs of transtentorial herniation in every case. preoperative i-v interpeak latenc ... | 2010 | 2871503 |
| opportunities for lay midwifery practice. | | 2010 | 2929822 |
| pharmacokinetics and effect on blood pressure of doxazosin in normal subjects and patients with renal failure. | the antihypertensive efficacy and pharmacokinetics of a single 1 mg oral dose of doxazosin were investigated in five healthy male volunteers, six patients with renal failure not on hemodialysis, and four patients with end-stage renal failure studied between two hemodialyses. the dialyzability of doxazosin was studied in five patients. the maximum fall in blood pressure of both volunteers and patients occurred between 4 and 8 hours. in four of five volunteers the blood pressure had returned to ba ... | 2010 | 2945688 |
| selective effects of enzyme treatment used for dissociating single cells on their gaba-receptor activities. | frog dorsal root ganglion (drg) cells treated with collagenase and trypsin were dissociated mechanically. the characteristics of dose-response curves of gaba-induced cl- currents (icl) were mainly studied using the "concentration-clamp" technique, by which the external solution around isolated single neurons was rapidly changed within a few milliseconds. the saturating maximum currents induced by various concentrations of gaba normalized to the peak icl induced by 10(-5) m gaba on the same neuro ... | 2010 | 2829067 |
| determination of pyrimidine 5'-nucleotidase (p5n) activity in whole blood as an index of lead exposure. | a simple method for determining pyrimidine 5'-nucleotidase (p5n) activity in whole blood has been developed, inhibiting the plasma activity for ump-hydrolysis by concanavalin (con a). con a specifically inhibits the activity of plasma 5'-nucleotidase (5n) but does not affect erythrocyte p5n activity. the anticoagulant edta partially inhibits 5n activity but slightly activates p5n. p5n activity determined by the present method with heparinised blood and con a was comparable with that by the metho ... | 2010 | 2840110 |
| cross-linking site in fibrinogen for alpha 2-plasmin inhibitor. | a plasma proteinase inhibitor, alpha 2-plasmin inhibitor (alpha 2pi), is cross-linked with alpha chain of fibrin(ogen) by activated coagulation factor xiii (plasma transglutaminase). alpha 2pi serves only as a glutamine substrate (amine acceptor) for activated factor xiii in the cross-linking reaction, and the cross-linking occurs between gln-2 of the alpha 2pi molecule and a lysine residue (amine donor) of fibrin(ogen) alpha chain, whose position was investigated. alpha 2pi and fibrinogen were ... | 2010 | 2877981 |
| [exorbitant responsibilities!]. | | 2010 | 2814197 |
| the organization of the cholinergic synapse. | | 2010 | 2904504 |
| peripheral neuropathy associated with mitochondrial myopathy. | twenty patients with mitochondrial myopathy were investigated for the presence of peripheral neuropathy. there were clinical features of a mild sensorimotor neuropathy in five patients (25%) and nerve conduction studies were abnormal in 10 patients (50%). electrophysiological studies of the whole group showed significant impairment of motor and sensory conduction compared with controls. sural nerve biopsy and morphometric studies were performed on four patients with clinical neuropathy. there wa ... | 2010 | 2849395 |
| low-dose aspirin in pregnancy. | in a prospective study, we evaluated the effects of low-dose aspirin on maternal and neonatal plasma 6-keto-prostaglandin (pg) f1 alpha concentration, platelet aggregation, platelet thromboxane production, and neonatal transitional circulation. forty women, at a mean (+/- sd) of 37 +/- 2 weeks' gestation, were randomized to receive (n = 10 each) placebo or 20, 60, or 80 mg of aspirin per day until delivery. maternal serum 6-keto-pgf1 alpha levels were not affected by these doses of aspirin, wher ... | 2010 | 2797631 |
| prognostic and therapeutic observations of manifestations in the genitourinary tract of adenocarcinoma of the colon and rectum. | to evaluate the significance of involvement of the genitourinary tract in adenocarcinoma of the colon and rectum, we received the records of 178 patients with adenocarcinoma of the colon and rectum admitted to the university of massachusetts medical center from 1980 to 1985. sixty-eight patients (38 per cent) had urologic manifestations categorized as ureteral obstruction or injury (34 per cent), invasion to the bladder or prostate, or both (10 per cent), isolated gross hematuria (18 per cent), ... | 2010 | 2814767 |
| the complete nucleotide sequence of tetanus toxin. | | 2010 | 3774547 |
| [pulmonary sarcoidosis with bullous development]. | | 2010 | 2966391 |
| [influence of the professional motivation in students of various areas in prevention oriented health behavior and the state of their teeth]. | | 2011 | 3256949 |
| [influence of the professional motivation in students of various areas in prevention oriented health behavior and the state of their teeth]. | | 2011 | 3256949 |
| blood culture collection techniques and bacterial contamination. | | 2011 | 3241743 |
| [pulmonary abscess in subjacent congenital malformation in infants]. | | 2011 | 3232901 |
| [caustic burns of the esophagus in childhood. our 14 years' experience]. | a 14-years revision (1972-1986) is made of 3,600 children attended to after ingesting some type of caustic agent. only 81 were admitted to hospital. we found a predominance in the 1-3 year age group. bleach was the caustic most frequently present but lye accounted for most major lesions. the more relevant symptoms were oropharyngeal lesions (85%), vomiting (26%) and sialorrhea (20%). oropharyngeal burns was the sign most often found in esophageal lesions (45%). the ingestion of ordinary househol ... | 2011 | 3232875 |
| determination of fentin residues in potatoes and celery. | | 2011 | 3232835 |
| the ascertainment sampling problem and estimation of genetic parameters when parental haplotypes are known. | comparisons of bias and standard errors of genetic parameter estimates arising from various estimation procedures are made by using contrived genetic data in which parental haplotypes are known in addition to the haplotypes of affected sibs. these comparisons show that knowledge of parental haplotypes can reduce standard errors of genetic parameter estimates by between 10% and 45% as compared to estimates when parental information is not available. the added information does not appear to change ... | 2011 | 3232696 |
| comparison of in vitro dissolution of proprietary methyl dopa preparations. | | 2011 | 3219716 |
| osmotic fragility model for red cell populations. | a model that predicts the osmotic fragility curve of a red cell population is developed by relating the critical osmotic pressure to the size distribution of the cells, determined by resistive pulse spectroscopy. two of the parameters involved, namely the normalized osmotic volume correction, b, and the swelling index, k, are previously determined from the experimental average properties of the population. from these values the critical volume of the cell is obtained, and is shown to be 6-12% la ... | 2011 | 3207827 |
| functional and biochemical features of alcohol dehydrogenase in four species of the obscura group of drosophila. | the biochemical features of adh of four drosophila species of the obscura group have been studied. the relationship between ethanol tolerance and adh activity has been investigated. propan-2-ol and acetone concentrations have been determined in propan-2-ol treated flies and adh activity has been followed during 96 h of propan-2-ol treatment. data on the adh system confirm constructed phylogenies based on electrophoretic variation and chromosome homologies. | 2011 | 3209073 |
| hla and hydatidiform mole. i. hla and abo antigen frequencies in couples with androgenetic and diandric conceptuses. | hla and abo antigen frequencies and mating rates were studied in couples with hydatidiform mole with known genomic origin. hla-a,b antigen frequencies among 60 patients and 59 spouses were not different from those found in the background population, neither in the subgroups regarded alone nor in the entire series. although not significant, an excess of hla-drw6 found in patients with androgenetic conceptions may be related to the anucleate ovi observed with androgenesis. the distribution of abo ... | 2011 | 3194901 |
| [surgery of cholesteatoma ears with good hearing]. | | 2011 | 3219644 |
| [effect of sex steroids on the lipoprotein profile]. | hyperandrogenemia is associated with relatively high ldl- and low hdl-cholesterol levels, increasing the risk of the development of arteriosclerotic disease. in three women suffering from androgen producing ovarian tumors, this observation could be confirmed. after surgical removal of the ovaries, lipoprotein profiles returned to normal. in contrast, androgens did not affect lipoproteins in two testicular feminized individuals. despite elevated testosterone levels, the lipoprotein profiles were ... | 2011 | 3234712 |
| [function of the kidneys and the renin-aldosterone system in women before and after use of intrauterine contraceptive devices]. | conflicting opinions exist concerning the use of various birth control methods for women suffering from kidney diseases. some researchers think kidney diseases are a contraindication for the use of iud; since iuds may cause inflammatory processes; others think that preventive therapy of extragenital diseases may make the use of iud possible. the article studies the functional condition of the urinary system and various hormone levels (renin, aldosterone, vasopressin, cortisol) in women using an ... | 2011 | 3322076 |
| sample size: when is enough enough? | | 2011 | 3195627 |
| chordoma in a chronic pain patient. | a 60-year-old woman was admitted to the hospital with a recurrence of low back pain. she was begun on a behavior modification pain control program. follow-up x-rays, including ct scan of the lumbosacral spine, showed a large tumor of the l3 vertebra. she subsequently underwent surgical resection of a large chordoma of the l3 vertebra and had good resolution of her back pain. | 2011 | 3160321 |
| [hyperuricemia in the joint syndrome in children]. | | 2011 | 3186400 |
| [usefulness of the diagnosis of grade iii placenta using ultrasonography in the management of prolonged pregnancy]. | | 2011 | 3154276 |
| the use of imipramine in minor motor seizures. | a study is presented of 15 pediatric patients treated with imipramine for uncontrolled seizures during the past two years. of these patients, 53% had an initial reduction of seizures of greater than 80%. at one year, 26% were still seizure-free. drop attacks were especially responsive to therapy; 100% (7/7) responded initially to imipramine therapy. most patients studied had been receiving valproate and another major antiepileptic drug prior to imipramine therapy. this study confirms previous re ... | 2011 | 3150277 |
| [disorders of the hypothalamo-hypophyseal-gonadal axis and erectile impotence]. | | 2011 | 3181023 |
| [progress in health services research. diagnostic related groups]. | | 2011 | 3133820 |
| interprofessional perspectives on blindness and low vision. | | 2011 | 3263048 |
| dosimetry for radiolabelled antibodies--macro or micro? | three approaches to calculating radiation absorbed doses and answering fundamental questions in radiolabelled antibody therapy are outlined. conventional macroscopic dosimetry is probably not appropriate for calculations on the small scale of normal tissue and tumour volumes that are of interest in therapy. a better though even more traditional approach is to use the results from beta particle dosimetry. these may be shown to apply down to quite small populations of cells. an approach using the ... | 2011 | 3162447 |