Publications

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emerging incidence of lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in australia.borrelia burgdorferi, the causative agent of lyme disease (ld), and babesia, bartonella, and ehrlichia species (spp.) are recognized tick-borne pathogens in humans worldwide. using serology and molecular testing, the incidence of these pathogens was investigated in symptomatic patients from australia.201122267937
genotypic diversity of an emergent population of borrelia burgdorferi at a coastal maine island recently colonized by ixodes scapularis.abstract the recent range expansion of ixodes scapularis has been accompanied by the emergence of borrelia burgdorferi. the development of genetic diversity in b. burgdorferi at these sites of emergence and its relationship to range expansion is poorly understood. we followed colonization of i. scapularis on a coastal maine island over a 17-year period. b. burgdorferi's emergence was documented, as was expansion of ospc strain diversity. ticks collected from rodents and vegetation were examine ...201222217172
do the level of energy reserves, hydration status and borrelia infection influence walking by ixodes ricinus (acari: ixodidae) ticks?summaryixodes ricinus horizontal movement within a humidity gradient and the influence of infection by borrelia burgdorferi sensu lato (s.l.) on tick walking were investigated. nymphs were placed within an arena containing a humidity gradient ranging from 45 to 95% relative humidity (rh). after 1 h of acclimation at 70% rh ticks were released so that they could either stay, or walk towards either the wet or the dry end. their position was recorded 2 h post-release. fat content was quantified and ...201222217387
lyme disease as an underlying cause of supraspinatus tendinopathy in an overhead athlete.background and purpose:/b>supraspinatus tendinopathy is a common cause of shoulder pain seen in overhead athletes, but to our knowledge no published cases present lyme disease as the underlying cause of tendinopathy. lyme disease is diagnosed primarily by clinical signs and symptoms and then supported by laboratory tests including western blot and enzyme-linked immunosorbant assay (elisa). this case demonstrates the importance of a physical therapist's input and clinical role in reaching the c ...201222247404
persistence of borrelia burgdorferi in rhesus macaques following antibiotic treatment of disseminated infection.the persistence of symptoms in lyme disease patients following antibiotic therapy, and their causes, continue to be a matter of intense controversy. the studies presented here explore antibiotic efficacy using nonhuman primates. rhesus macaques were infected with b. burgdorferi and a portion received aggressive antibiotic therapy 4-6 months later. multiple methods were utilized for detection of residual organisms, including the feeding of lab-reared ticks on monkeys (xenodiagnosis), culture, imm ...201222253822
of ticks, mice and men: understanding the dual-host lifestyle of lyme disease spirochaetes.in little more than 30 years, lyme disease, which is caused by the spirochaete borrelia burgdorferi, has risen from relative obscurity to become a global public health problem and a prototype of an emerging infection. during this period, there has been an extraordinary accumulation of knowledge on the phylogenetic diversity, molecular biology, genetics and host interactions of b. burgdorferi. in this review, we integrate this large body of information into a cohesive picture of the molecular and ...201222230951
potential infectious etiology of behçet's disease.behçet's disease is a multisystem inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. the cause of behçet's disease remains unknown, but epidemiologic findings suggest that an autoimmune process is triggered by an environmental agent in a genetically predisposed individual. an infectious agent could operate through molecular mimicry, and subsequently the disease could be perpetuated by an abnormal immune response to an autoantigen in ...201222254152
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