| in vitro activity of ten essential oils against sarcoptes scabiei. | the development of alternative approaches in ectoparasite management is currently required. essential oils have been demonstrated to exhibit fumigant and topical toxicity to a number of arthropods. the aim of the present study was to assess the potential efficacy of ten essential oils against sarcoptes scabiei. | 2016 | 27876081 |
| parasites and vector-borne diseases in client-owned dogs in albania: infestation with arthropod ectoparasites. | to establish the diversity and seasonality of ectoparasite infestation in client-owned dogs in albania, 602 dogs visiting four small animal clinics in tirana from march 2010 to april 2011 inclusive were examined for ectoparasites by full body search and total body comb. in addition, ear swab specimens collected from all dogs and scrapings taken from skin lesions suspicious of mite infestation were examined for parasitic mites. overall, 93 dogs (15.4 %, 95%ci 12.6-18.6) were demonstrated to be in ... | 2017 | 27796564 |
| smallholder pig production: prevalence and risk factors of ectoparasites. | a cross-sectional study was carried out in the mbeya region, tanzania, with the aim of describing the distribution and diversity of ectoparasites on pigs, within confinement and free-range production systems of smallholder farms. a total of 128 farms were surveyed, with 96 practising confinement and 32 practising free-range production systems. the prevalence of ectoparasites on pigs within confinement and free-range production systems was 24% and 84%, respectively. logistic regression analyses r ... | 2013 | 23357599 |
| a survey of ectoparasite infestation in dogs in tehran, iran. | this survey was conducted to identify and estimate the frequencies of ectoparasites of dogs in tehran, iran. a total of 143 dogs attended at the small animal hospital of the veterinary school, the university of tehran, were examined for the presence of ectoparasites and dermatological lesions. ectoparasite specimens and blood samples were sent to parasitology and hematology laboratories, respectively. ticks were the most frequent ectoparasite (36.4%, 52/143), followed by fleas (29.4%, 42/143), m ... | 2012 | 23070452 |
| identification of antigenic sarcoptes scabiei proteins for use in a diagnostic test and of non-antigenic proteins that may be immunomodulatory. | scabies, caused by the mite, sarcoptes scabiei, infects millions of humans, and many wild and domestic mammals. scabies mites burrow in the lower stratum corneum of the epidermis of the skin and are the source of substances that are antigenic or modulate aspects of the protective response of the host. ordinary scabies is a difficult disease to diagnose. | 2017 | 28604804 |
| genetic characterization of sarcoptes scabiei from black bears (ursus americanus) and other hosts in eastern united states. | since the early 1990s there has been an increase in the number of cases and geographic expansion of severe mange in the black bear (ursus americanus) population in pennsylvania. although there are 3 species of mites associated with mange in bears, sarcoptes scabiei has been identified as the etiologic agent in these pennsylvania cases. historically s. scabiei-associated mange in bears has been uncommon and sporadic although it is widespread and relatively common in canid populations. to better u ... | 2017 | 28639466 |
| the threatening but unpredictable sarcoptes scabiei: first deadly outbreak in the himalayan lynx, lynx lynx isabellinus, from pakistan. | although neglected, the mite sarcoptes scabiei is an unpredictable emerging parasite, threatening human and animal health globally. in this paper we report the first fatal outbreak of sarcoptic mange in the endangered himalayan lynx (lynx lynx isabellinus) from pakistan. a 10-year-old male himalayan lynx was found in a miserable condition with severe crusted lesions in chitral district, and immediately died. post-mortem examination determined high s. scabiei density (1309 mites/cm(2) skin). it i ... | 2016 | 27435176 |
| new techniques to collect live sarcoptes scabiei and evaluation of methods as alternative diagnostics for infection. | sarcoptes scabiei is a widespread, highly contagious skin disease that affects many mammals including humans. the biological characteristics of s. scabiei remain unclear. therefore, the ability to collect adequate amount of mites for studies is required to advance our understanding of the parasite. the present study aimed to find a method to collect an adequate amount of live s. scabiei mites within a short time frame. the cornified layer and fur from an infected raccoon dog were inserted into a ... | 2017 | 28124136 |
| are humans the initial source of canine mange? | scabies, or mange as it is called in animals, is an ectoparasitic contagious infestation caused by the mite sarcoptes scabiei. sarcoptic mange is an important veterinary disease leading to significant morbidity and mortality in wild and domestic animals. a widely accepted hypothesis, though never substantiated by factual data, suggests that humans were the initial source of the animal contamination. in this study we performed phylogenetic analyses of populations of s. scabiei from humans and fro ... | 2016 | 27015813 |
| effective treatment for improving the survival rate of raccoon dogs infected with sarcoptes scabiei. | sarcoptes scabiei is one of the important external parasites. although ivermectin is the recommended treatment, many raccoon dogs (nyctereutes procyonoides) that were rescued and brought to the kanazawa zoological gardens (yokohama, japan) have died because of s. scabiei, even after receiving single ivermectin treatment. therefore, supportive treatment should be required. the present study revealed the number of animals that survived was greater after the administration of ivermectin along with ... | 2014 | 24813465 |
| epidemiology of sarcoptic mange in free-ranging raccoon dogs (nyctereutes procyonoides) in yokohama, japan. | free-ranging raccoon dogs (nyctereutes procyonoides) from nogeyama zoological gardens, kanazawa zoological gardens, and yokohama zoological gardens frequently rescued dogs having sarcoptes scabiei infestation. however, the epidemiology of s. scabiei infestation has not yet been elucidated. in the present study, we investigated the epidemiology of s. scabiei infestation in raccoon dogs and its influence on the population of masked palm civets in yokohama, japan. we examined records of raccoon dog ... | 2013 | 22902260 |
| genetic epidemiology and pathology of raccoon-derived sarcoptes mites from urban areas of germany. | the raccoon, procyon lotor (carnivora: procyonidae), is an invasive species that is spreading throughout europe, in which germany represents its core area. here, raccoons mostly live in rural regions, but some urban populations are already established, such as in the city of kassel, or are starting to build up, such as in berlin. the objective of this study was to investigate sarcoptes (sarcoptiformes: sarcoptidae) infections in racoons in these two urban areas and to identify the putative origi ... | 2014 | 25171612 |
| sarcoptic mange in endangered kit foxes (vulpes macrotis mutica): case histories, diagnoses, and implications for conservation. | the san joaquin kit fox ( vulpes macrotis mutica) is a federally endangered small carnivore whose distribution is limited to the san joaquin valley in central california. population decline is due to profound habitat loss, and conservation of all remaining populations is critical. a robust urban population occurs in the city of bakersfield. in spring of 2013, putative cases of mange were reported in this population. mites from affected animals were confirmed to be sarcoptes scabiei morphological ... | 2017 | 27669012 |
| pathology of sarcoptic mange in red foxes (vulpes vulpes): macroscopic and histologic characterization of three disease stages. | sarcoptic mange is a highly contagious skin disease that can have a devastating impact on affected wild mammal populations. there are notable variations in the clinical and pathologic picture of sarcoptic mange among species and among conspecifics. however, the origin of these variations is unclear. we propose a classification scheme for skin lesions associated with sarcoptes scabiei infestation to provide a basis for a subsequent risk factor analysis. we conducted a case-control study focused o ... | 2013 | 23307375 |
| numerical responses by populations of red fox and mountain hare during an outbreak of sarcoptic mange. | during a severe outbreak of sarcoptic mange (sarcoptes scabiei vulpes) starting among red foxes (vulpes vulpes) in sweden in the 1970s, we studied: 1) the establishment and spread of the disease in northernmost sweden (by inquiries), and 2) the 1970-84 bag records for foxes and mountain hares (lepus timidus) (an alternative prey to the fox's main prey, voles). since the first case of sarcoptic mange in 1975 the disease spread rapidly, with >50% of the hunting organizations having reported the di ... | 1987 | 28311970 |
| reflectance confocal microscopy in infectious diseases. | in vivo reflectance confocal microscope (rcm) is a high-resolution non-invasive imaging technique that was initially focused on the diagnosis of skin cancers. a rising number of other indications have been later described for the diagnosis and management of inflammatory and infectious dermatological disorders. rcm can identify cutaneous parasites that are not visible to naked eye such as sarcoptes scabiei and demodex folliculorum and it allows to better identify the different body parts of bigge ... | 2015 | 26129682 |
| allergen homologs in the euroglyphus maynei draft genome. | euroglyphus maynei is a house dust mite commonly found in homes worldwide and is the source of allergens that sensitize and induce allergic reactions in humans. it is the source of species-specific allergens as well as allergens that are cross-reactive with the allergens from house dust mites dermatophagoides farinae and d. pteronyssinus, and the ectoparasitic scabies mite sarcoptes scabiei. the genomics, proteomics and molecular biology of e. maynei and its allergens have not been as extensivel ... | 2017 | 28829832 |
| proteases of dermatophagoides pteronyssinus. | since the discovery that der p 1 is a cysteine protease, the role of proteolytic activity in allergic sensitization has been explored. there are many allergens with proteolytic activity; however, exposure from dust mites is not limited to allergens. in this paper, genomic, transcriptomic and proteomic data on dermatophagoides pteronyssinus (dp) was mined for information regarding the complete degradome of this house dust mite. d. pteronyssinus has more proteases than the closely related acari, d ... | 2017 | 28587273 |
| vaccination with recombinant actin from scab mites and evaluation of its protective efficacy against psoroptes cuniculi infection. | the mite psoroptes cuniculi is globally widespread and has a serious impact on commercial rabbit breeding. current treatment methods are based on chemotherapy. because of the disadvantages of these methods, alternative measures are required, and vaccination is one of the most promising strategies. here, we cloned and expressed the recombinant p. cuniculi actin gene (rpc-act). antiserum levels against rpc-act in rabbits were used to locate actin distribution in mite sections. challenge trials wer ... | 2013 | 23078134 |
| expression and characterisation of a sarcoptes scabiei protein tyrosine kinase as a potential antigen for scabies diagnosis. | scabies is a disease that harms humans and other animals that is caused by the itch mite sarcoptes scabiei burrowing into the stratum corneum of the skin. in the early stages of scabies, symptoms are often subclinical and there are no effective diagnostic methods. herein, we cloned, expressed and characterised an s. scabiei protein tyrosine kinase (ssptk) and evaluated its diagnostic value as a recombinant antigen in rabbit during the early stages of sarcoptes infestation. the ssptk protein is ~ ... | 2017 | 28852108 |
| epizootic of sarcoptic mange in raccoon dogs (nyctereutes procyonoides) in relation to population density. | to examine outbreaks of mange in raccoon dogs (nyctereutes procyonoides) with respect to population density, we analyzed camera trap videos, and isolated mites from raccoon dog carcasses. in a camera trapping survey, we categorized the skin condition of raccoon dogs, and used a number of independent videos to calculate the relative abundance index (rai). the rai of raccoon dogs with alopecia increased following an increase in the rai of those without alopecia. among 27 raccoon dog carcasses, 12 ... | 2018 | 29353863 |
| a case report of real-time in vivo demonstration of sarcoptes scabiei. | scabies is a pruritic dermatosis caused by the ectoparasite sarcoptes scabiei var. hominis. the diagnosis of scabies is usually made on clinical grounds, but histopathological and/or dermoscopic examinations may sometimes be of assistance. however, these diagnostic modalities do not offer a detailed in vivo demonstration of the motile microorganism. reflectance confocal microscopy (rcm) is a relatively novel imaging modality that permits in vivo examination of the skin at a resolution similar to ... | 2017 | 29318996 |
| sarcoptes scabiei on hedgehogs in new zealand. | european hedgehogs (erinaceus europaeus) were introduced into new zealand from britain during the period from 1869 to the early 1900s. the only mite found on new zealand hedgehogs in early studies was caparinia tripilis, with sarcoptes scabiei first being reported in 1996. the aim of this study was to investigate the prevalence of sarcoptes infestation on hedgehogs in new zealand, the number of mites found and the degree of mange observed. dead hedgehogs were collected from veterinary clinics, r ... | 2018 | 29318391 |
| | in case of pruritus, always consider scabies! scabies is an itching skin disease caused by the mite sarcoptes scabiei which affects more than 100 million people worldwide. regarded as a neglected tropical disease by the who, it is a major public health burden in endemic areas. as direct skin-to-skin contact is the main route of transmission family members and sexual partners are often affected. typical presentation includes a severely pruritic rash with predilection for the extremities and the t ... | 2017 | 29292916 |
| scabies, crusted (norwegian) scabies and the diagnosis of mite sensitisation. | scabies is observed with relatively high frequency in allergy and dermatology clinics in developing countries where poor sanitary conditions are prevalent and increasingly in some areas of the world with increased immigrant populations. since the immunological response to scabies mites includes the production of ige class antibodies to sarcoptes scabiei allergens which cross-react with dermatophagoides major allergens der p 1 and der p 2, positive immediate-type skin tests to house dust mite ext ... | 2017 | 29279260 |
| histopathology, microbiology and the inflammatory process associated with sarcoptes scabiei infection in the iberian ibex, capra pyrenaica. | sarcoptic mange has been identified as the most significant infectious disease affecting the iberian ibex (capra pyrenaica). despite several studies on the effects of mange on ibex, the pathological and clinical picture derived from sarcoptic mange infestation is still poorly understood. to further knowledge of sarcoptic mange pathology, samples from ibex were evaluated from histological, microbiological and serological perspectives. | 2017 | 29202802 |
| scabies in the age of increasing drug resistance. | scabies is an infestation of the skin by the mite sarcoptes scabiei. it manifests with pruritic erythematous papules and excoriations, in addition to the pathognomonic burrows. multiple drugs can be used for treatment, but resistance to conventional therapy is increasing throughout the years. this paper will review the mechanisms of resistance proposed in the literature and some of the potential solutions to this problem. | 2017 | 29190303 |
| crusted scabies due to indiscriminate use of glucocorticoid therapy in infant. | crusted or norwegian scabies is a parasitic infectious disease caused by sarcoptes scabiei var. hominis that mainly affects immunocompromised individuals and those with neurological patients. we report a case of crusted scabies in a 4-month-old infant who had been treated erroneously for atopic dermatitis with high doses of corticosteroids. this initial misdiagnosis associated with the abusive use of corticosteroid facilitated the evolution of scabies to crusted scabies and its main complication ... | 2017 | 29186253 |
| mitochondrial genome sequencing reveals potential origins of the scabies mite sarcoptes scabiei infesting two iconic australian marsupials. | debilitating skin infestations caused by the mite, sarcoptes scabiei, have a profound impact on human and animal health globally. in australia, this impact is evident across different segments of australian society, with a growing recognition that it can contribute to rapid declines of native australian marsupials. cross-host transmission has been suggested to play a significant role in the epidemiology and origin of mite infestations in different species but a chronic lack of genetic resources ... | 2017 | 29183283 |
| sarcoptic mange in wombats-a review and future research directions. | sarcoptic mange is caused by the mite sarcoptes scabiei and has recently been recognized as an emerging infectious disease of wildlife worldwide. the mite is one of the main causes of population decline in southern hairy-nosed (lasiorhinus latifrons) and bare-nosed wombats (vombatus ursinus). this review focuses on sarcoptes scabiei infestations in wombats and provides insights into why the disease may be so prevalent in wombats. current treatment practices and trials conducted in the field to r ... | 2017 | 29150905 |
| molecular characteristics and serodiagnostic potential of chitinase-like protein from sarcoptes scabiei. | scabies, caused by the mite sarcoptes scabiei, is an allergic skin disease that affects millions of people and other mammals worldwide. this highly contagious parasitic disease is among the top 50 epidemic disease and is regarded as a neglected tropical disease. diagnosis of scabies is difficult in the early stage, and the pathogenesis of scabies is not currently clear. here, we expressed, identified and located the chitinase-like protein of s. scabiei (ssclp), and evaluated its potential as an ... | 2017 | 29137399 |
| identification of a novel pyp-1 gene in sarcoptes scabiei and its potential as a serodiagnostic candidate by indirect-elisa. | scabies is a parasitic disease caused by the ectoparasite sarcoptes scabiei, affecting different mammalian species, including rabbits, worldwide. in the present study, we cloned and expressed a novel inorganic pyrophosphatase, ssc-pyp-1, from s. scabiei var. cuniculi. immunofluorescence staining showed that native ssc-pyp-1 was localized in the tegument around the mouthparts and the entire legs, as well as in the cuticle of the mites. interestingly, obvious staining was also observed on the feca ... | 2017 | 29113603 |
| ignoring the "itch": the global health problem of scabies. | infestation with sarcoptes scabiei var. hominis is a common human parasitic affliction endemic in tropical developing countries. scabies is transmitted by close person-person contact, and outbreaks have been reported in reception centers for asylum seekers. scabies presents clinically as extremely pruritic excoriated papules and linear burrows in the skin. this infestation predisposes to bacterial skin infections that can result in serious complications affecting the kidneys and possibly the hea ... | 2017 | 29016295 |
| is the simple saline mount technique more effective than potassium hydroxide for the microscopic detection of sarcoptes scabiei? | not applicable. | 2017 | 28985134 |
| scabies masquerading as bullous pemphigoid: scabies surrepticius. | scabies, a parasitic infestation caused by the mite sarcoptes scabiei, is diagnosed by observing either the mite, its ova, or its excrement. the mite tracts, known as burrows and a characteristic presentation of the pruritic condition, are typically found on the web spaces between the fingers. other cutaneous lesions include excoriated papules, pustules, and vesicles. however, atypical clinical variants of scabies, such as bullous, crusted, hidden, incognito, nodular, and scalp forms of the para ... | 2017 | 28883737 |
| sarcoptes scabiei alters follicular dynamics in female iberian ibex through a reduction in body weight. | normal development of the ovarian cycle is a key factor in ensuring female reproductive success. sarcoptes scabiei has been shown to induce changes in host physiology, although the effects of this mite on the female reproductive cycle are still unknown. in an attempt to clarify this issue, the number of ovarian structures (primary follicles, secondary follicles, graaf follicles, corpus luteum and corpus albicans) in female iberian ibex (capra pyrenaica) affected by sarcoptic mange was explored b ... | 2017 | 28807285 |
| host immune responses to the itch mite, sarcoptes scabiei, in humans. | scabies is a parasitic disease due to infestation of skin by the burrowing mite sarcoptes scabiei. scabies is a major public health problem and endemic in resource poor communities worldwide affecting over 100 million people. associated bacterial infections cause substantial morbidity, and in severe cases can lead to renal and cardiac diseases. mite infestation of the skin causes localised cutaneous inflammation, pruritus, skin lesions, and allergic and inflammatory responses are mounted by the ... | 2017 | 28797273 |
| characterization of sarcoptes scabiei tropomyosin and paramyosin: immunoreactive allergens in scabies. | scabies is a human skin disease due to the burrowing ectoparasite sarcoptes scabiei var. hominis resulting in intense itching and inflammation and manifesting as a skin allergy. because of insufficient mite material and lack of in vitro propagation system for antigen preparation, scabies is a challenging disease to develop serological diagnostics. for allergen characterization, full-length s. scabiei tropomyosin (sar s 10) was cloned, expressed in pet-15b, and assessed for reactivity with ige an ... | 2017 | 28722633 |
| outbreaks of sarcoptic mange in free-ranging koala populations in victoria and south australia: a case series. | to describe outbreaks of sarcoptic mange caused by sarcoptes scabiei in free-ranging koalas in victoria (december 2008 to november 2015) and south australia (october 2011 to september 2014). | 2017 | 28653387 |
| european guideline for the management of scabies. | scabies is caused by sarcoptes scabiei var. hominis. the disease can be sexually transmitted. patients' main complaint is nocturnal itch. disseminated, excoriated, erythematous papules are usually seen on the anterior trunk and limbs. crusted scabies occurs in immunocompromised hosts and may be associated with reduced or absent pruritus. recommended treatments are permethrin 5% cream, oral ivermectin and benzyl benzoate 25% lotion. alternative treatments are malathion 0.5% aqueous lotion, iverme ... | 2017 | 28639722 |
| a review of sarcoptes scabiei: past, present and future. | the disease scabies is one of the earliest diseases of humans for which the cause was known. it is caused by the mite, sarcoptes scabiei, that burrows in the epidermis of the skin of humans and many other mammals. this mite was previously known as acarus scabiei degeer, 1778 before the genus sarcoptes was established (latreille 1802) and it became s. scabiei. research during the last 40 years has tremendously increased insight into the mite's biology, parasite-host interactions, and the mechanis ... | 2017 | 28633664 |
| sarcoptic mange infestation in rabbits in an organized farm at tamil nadu. | sarcoptes scabiei are burrowing mites which causes major constraints in rabbit production. eighty-eight rabbits were examined for mange infestation at university research farm, tamil nadu. overall incidence of mange infestation in rabbit was 23.6 %. on microscopical examination, the mite was identified as sacoptes scabiei var cuniculi. among the breeds, soviet chinchilla were found to be infested more (57.14 %) followed by new zealand white (28.57 %) and white giant (28.57 %). among the age grou ... | 2017 | 28615854 |
| evaluation of oxidant/antioxidant balance in iberian ibex (capra pyrenaica) experimentally infested with sarcoptes scabiei. | oxidative stress (os) is an imbalance between radical-generating and radical scavenging activity, resulting in oxidation products and tissue damage. although some studies have been done in other species, there is a lack of information about the oxidative/antioxidant status in the iberian ibex (capra pyrenaica) affected by sarcoptic mange. to clarify this fact, albumin, catalase (cat), glutathione peroxidase (gsh-px), superoxide dismutase (sod), paraoxonase-1 (pon-1), glutathione reductase (gr), ... | 2017 | 28606327 |
| gene silencing by rna interference in sarcoptes scabiei: a molecular tool to identify novel therapeutic targets. | scabies is one of the most common and widespread parasitic skin infections globally, affecting a large range of mammals including humans, yet the molecular biology of sarcoptes scabiei is astonishingly understudied. research has been hampered primarily due to the difficulty of sampling or culturing these obligatory parasitic mites. a further and major impediment to identify and functionally analyse potential therapeutic targets from the recently emerging molecular databases is the lack of approp ... | 2017 | 28601087 |
| increase the risk of intellectual disability in children with scabies: a nationwide population-based cohort study. | scabies is a common and distressing disease caused by the mite sarcoptes scabiei var. hominis. psychiatric disorder in childhood is an important disease and easily neglected. there are several similarities in scabies and psychiatric disorders in childhood (pdc). both of them may present with pruritus. they are relatively common in patients with lower socioeconomic status and crowded environment. furthermore, immune-mediated inflammatory processes play a role in the pathophysiology in both diseas ... | 2017 | 28591057 |
| in vitro efficacy of moxidectin versus ivermectin against sarcoptes scabiei. | moxidectin is under consideration for development as a treatment for human scabies. as some arthropods show decreased sensitivity to moxidectin relative to ivermectin, it was important to assess this for sarcoptes scabieiin vitro assays showed that the concentration of moxidectin required to kill 50% of mites was lower than that of ivermectin (0.5 μm versus 1.8 μm at 24 h; p < 0.0001). this finding provides further support for moxidectin as a candidate for the treatment of human scabies. | 2017 | 28559258 |
| systematic review of the diagnosis of scabies in therapeutic trials. | human scabies (infestation with the mite sarcoptes scabiei var hominis) causes a significant disease burden worldwide, yet there are no agreed diagnostic guidelines. we aimed to determine whether a consistent approach to diagnosing scabies has been used for published scabies therapeutic trials. the data sources used were the medline, embase and cochrane databases, from 1946 to 29 august 2013. eligible studies were trials of therapeutic interventions against scabies in human subjects, published i ... | 2017 | 28556185 |
| transcriptome-microrna analysis of sarcoptes scabiei and host immune response. | scabies is a parasitic disease, caused by the mite sarcoptes scabiei, and is considered one of the top 50 epidemic diseases and one the most common human skin disease, worldwide. allergic dermatitis, including an intense itch, is a common symptom, however diagnosis is difficult and there is currently no effective vaccine. the goal of this study was to examine the immune interaction mechanism of both s. scabiei and infected hosts. mrna-seq and microrna-seq were conducted on the s. scabiei mite an ... | 2017 | 28542251 |
| laboratory diagnosis of scabies using a simple saline mount: a clinical microbiologist's report. | scabies is a skin condition caused by infestation of the mite sarcoptes scabiei. sarcoptes scabiei var. hominis is an arthropod member belonging to the order acarina. scabies is present throughout the world and is prevalent in all age groups, mostly involving people frequently in contact with animals, children, women, and elderly people. predisposing factors for scabies include individuals with immunosuppressive conditions and people residing under low socioeconomic conditions. skin lesions that ... | 2017 | 28435762 |
| [scabies]. | | 2017 | 28417383 |
| misdiagnosed crusted scabies in an aids patient leads to hyperinfestation. | crusted scabies is a severe, highly contagious form of classic scabies caused by the mite sarcoptes scabiei var hominis. crusted scabies is more common in immunosuppressed populations and overcrowded environments. in this condition, the host's immune system is overwhelmed and unable to defend against the mites on the skin, resulting in hyperinfestation of the host. diagnosis can be challenging because the condition resembles other common skin conditions, such as plaque psoriasis. furthermore, de ... | 2017 | 28398415 |
| scabies in a bilateral hand allograft recipient: an additional mimicker of acute skin rejection in vascularized composite allotransplantation. | vascularized composite tissue allografts include skin, which frequently undergoes, in the early post-graft period, acute rejections. the diagnosis of acute rejection may be difficult as it can be mimicked by several dermatoses. we present a bilateral hand allograft recipient who developed, 16.5 years post-graft, cutaneous lesions raising suspicion about rejection. physical examination and skin biopsy were diagnostic of scabies. this ectoparasitosis should be added in the list of dermatoses that ... | 2017 | 28211139 |
| a scabies outbreak in a diabetic and collagen disease ward: management and prevention. | scabies is an infection caused by sarcoptes scabiei. in developed countries, scabies remains an important public health problem in hospitals and care facilities among elderly or immunocompromised patients. there are a number of medical providers who have not experienced scabies and there has been confusion surrounding its management and prevention. therefore, the aim of the present study was to identify the optimal approach for the management and prevention of scabies. a scabies outbreak occurre ... | 2016 | 28105102 |
| [scabies of the nail unit in an infant]. | there are no guidelines regarding the management of scabies in infants and recurrence is common at this age. we report the case of an infant with subungual hyperkeratosis and ungual lesions subsequent to classic scabies. | 2017 | 28063594 |
| s1 guidelines on the diagnosis and treatment of scabies - short version. | the goals of this german guideline are the improvement of diagnosis and therapy of scabies, the implementation of a coordinated action in outbreaks of scabies, and the control of this infestation in large migration or refugee flows.sarcoptes scabiei var. hominis is transmitted by direct skin-to-skin contact of sufficient duration. the infectivity of female mites when removed from patients does not exceed 48 hours at room temperature (21°c) and relative humidity of 40-80%. the risk of infection r ... | 2016 | 27879074 |
| molecular characterization of calmodulin from sarcoptes scabiei. | scabies, caused by the mite sarcoptes scabiei, is a highly contagious parasitic disease that affects millions of people and other mammals worldwide. calmodulin (cam) is an important calcium sensor that participates in various critical physiological processes. in this study, the cam of sarcoptes scabiei (sscam) was cloned and expressed, and sequence analyses were performed using bioinformatics tools. recombinant sscam (rsscam) was used to detect antigenicity using immunoblotting assays, and the s ... | 2017 | 27840198 |
| [scabies in childhood and adolescence]. | scabies is a common parasitosis, occurring worldwide and at any age that impairs the quality of life of patients and their families by the itching and the stigmatization. the main aims of therapy are destroying the mites sarcoptes scabiei var. hominis that infect the stratum corneum and reduction of the itching. this requires detailed clarification for the patients and the parents of affected children as the instructions for the use of the drugs and also the necessary additional steps are often ... | 2016 | 27826663 |
| report - most common body parts infected with scabies in children and its control. | scabies a skin disease caused by mite sarcoptes scabiei is common in pakistan and spreads mostly where there is frequent skin to skin contact. in the present study children belonging to four age groups 0-3 years, 4-6 years, 7-9 years and 10-12 years attending baqai institute and hospital gadap from june-september 2013 were examined. the association between scabies of different human parts and age for boys was significant (p<0.01), while for girls it was highly significant (p<0.001). the most fre ... | 2016 | 27731834 |
| efficacy of fluralaner in 17 dogs with sarcoptic mange. | there are few licensed options for the treatment of canine sarcoptic mange. | 2016 | 27511592 |
| vaccination of rabbits with immunodominant antigens from sarcoptes scabiei induced high levels of humoral responses and pro-inflammatory cytokines but confers limited protection. | vaccination is an attractive ecological alternative to the use of acaricides for parasite control. however, effective anti-parasite vaccines against sarcoptic mange have not yet been developed. the purpose of this study was first to identify sarcoptes scabiei immunodominant antigens and second to evaluate them as vaccine candidates in a rabbit/s. scabiei var. cuniculi model. | 2016 | 27502394 |
| a case of facial sarcoptes scabiei in a female child. | | 2016 | 27489439 |
| comparative efficacy of pour-on eprinomectin and ivermectin against sarcoptes scabiei in buffaloes. | the efficacy of eprinomectin and ivermectin pour-on was evaluated against sarcoptes scabiei in naturally infested buffaloes. eighteen animals were allocated into three groups (a, b and c) of six animals each. animals in group a were treated with eprinomectin (pour-on) @ 0.5 mg/kg; group b with ivermectin (pour-on) @ 0.2 mg/kg while group c served as untreated controls. skin scrapings were examined on days 0, 7, 14, 21, 28 and 42 post-treatment (pt). skin scrapings were found free for mites on da ... | 2016 | 27413304 |
| efficacy of fluralaner administered either orally or topically for the treatment of naturally acquired sarcoptes scabiei var. canis infestation in dogs. | the efficacy of fluralaner, formulated as a chewable tablet (bravecto™) or topical solution (bravecto™ spot-on solution), was evaluated against naturally acquired sarcoptes scabiei var. canis infestation in dogs. | 2016 | 27387742 |
| efficacy of afoxolaner in a clinical field study in dogs naturally infested with sarcoptes scabiei. | the acaricidal efficacy of afoxolaner (nexgard(®), merial) was evaluated against sarcoptes scabiei var. canis in a field efficacy study, when administered orally at a minimum dose of 2.5 mg/kg to dogs naturally infested with the mites. twenty mixed-breed dogs of either sex (6 males and 14 females), aged over 6 months and weighing 4-18 kg, were studied in this randomised controlled field efficacy trial. dogs, naturally infested with sarcoptes scabiei var. canis confirmed by skin scrapings collect ... | 2016 | 27317462 |
| scabies: advances in noninvasive diagnosis. | scabies is a common, highly contagious skin parasitosis caused by sarcoptes scabiei var. hominis. early identification and prompt treatment of infested subjects is essential, as missed diagnosis may result in outbreaks, considerable morbidity, and significantly increased economic burden. the standard diagnostic technique consists of mites' identification by microscopic examination of scales obtained by skin scraping. this is a time-consuming and risk-associated procedure that is also not suitabl ... | 2016 | 27311065 |
| correction: sarcoptes scabiei: the mange mite with mighty effects on the common wombat (vombatus ursinus). | | 2016 | 27078256 |
| de novo rna-seq and functional annotation of sarcoptes scabiei canis. | the transcriptomic data of sarcoptes is still lacking in the public database due to the difficulty in extracting high-quality rna from tiny mites with thick chitin. in this study, total rna was extracted from live sarcoptes mites for quality assessment, rna-seq, functional annotation, and coding region (cd) prediction and verification. the results showed that the sample jmq-lngm was qualified for cdna library construction. firstly, agilent 2100 detection showed that the rna baseline was smooth a ... | 2016 | 26997341 |
| [crusted scabies: a review]. | crusted scabies is a rare and severe form of infestation by sarcoptes scabies var. hominis. it is characterized by profuse hyperkeratosis containing over 4000 mites per gram of skin, with treatment being long and difficult. the condition is both direct and indirectly contagious. it has a central role in epidemic cycles of scabies, the incidence of which is on the rise in economically stable countries. recent discoveries concerning the biology of mites, the pathophysiology of hyperkeratosis and t ... | 2016 | 26948093 |
| sarcoptes scabiei: the mange mite with mighty effects on the common wombat (vombatus ursinus). | parasitism has both direct and indirect effects on hosts. indirect effects (such as behavioural changes) may be common, although are often poorly described. this study examined sarcoptic mange (caused by the mite sarcoptes scabiei) in the common wombat (vombatus ursinus), a species that shows severe symptoms of infection and often causes mortality. wombats showed alterations to above ground behaviours associated with mange. infected wombats were shown to be active outside of the burrow for longe ... | 2016 | 26943790 |
| efficacy and safety of a novel oral isoxazoline, sarolaner (simparica™), for the treatment of sarcoptic mange in dogs. | the efficacy of the novel isoxazoline, sarolaner (simparica™) was investigated in dogs with clinical signs consistent with sarcoptic mange and harbouring natural infestations of sarcoptes scabiei. one placebo-controlled laboratory study and one multi-centred field study with a commercial comparator containing imidacloprid/moxidectin (advocate(®) spot-on) were conducted. oral or topical treatments were administered on days 0 and 30. up to 10 skin scrapings were taken for the assessment of s. scab ... | 2016 | 26928658 |
| treatment of scabies: comparison of lindane 1% vs permethrin 5. | scabies, whose etiologic agent is sarcoptes scabiei, is a neglected parasitic disease that is a major public health problem in many resourcepoor regions. its current therapies include benzyl benzoate, lindane, permethrin, sulfur, crotamiton, monosulfiram, and oral ivermectin. the aim of this study was to compare the efficacy and safety of lindane 1% lotion vs permethrin 5% in the treatment of scabies. a total of 120 patients with scabies attending a dermatology outpatient department were include ... | 2016 | 26861425 |
| case report of individual with cutaneous immunodeficiency and novel 1p36 duplication. | crusted or norwegian scabies is an infectious skin dermatopathology usually associated with an underlying immunodeficiency condition. it is caused when the mite sarcoptes scabiei infects the skin, and the immune system is unable to control its spread, leading to a massive hyperinfestation with a simultaneous inflammatory and hyperkeratotic reaction. this is the first report of a novel 1p36 duplication associated with a recurrent infection of crusted scabies. | 2016 | 26834495 |
| a proteomic analysis of sarcoptes scabiei (acari: sarcoptidae). | the pruritic skin disease scabies is caused by the burrowing of the itch mite sarcoptes scabiei (de geer). it is difficult to diagnose this disease because its symptoms often resemble those of other skin diseases. no reliable blood or molecular diagnostic test is available. the aim of this project was to begin to characterize the scabies proteome to identify scabies mite proteins, including those that may be useful in the development of a diagnostic test or vaccine. various scabies mite extracts ... | 2016 | 26792847 |
| sarcoptic mange infestation in pigs: an overview. | sarcoptic mange infestation in pigs is caused by sarcoptes scabiei var. suis. it is the most common mange infestation of pigs. the parasite is distributed worldwide. pig owners are generally concerned about the internal parasitic infections and ignored the external parasitic infestations. but the external parasitic infestation with s. scabiei var. suis has economic significance as it causes morbidity, mortality, decreased fertility and feed conversion ratio in pigs. keeping in view of importance ... | 2015 | 26688620 |
| erratum: universal conventional and real-time pcr diagnosis tools for sarcoptes scabiei. | | 2015 | 26642880 |
| epidemiological and therapeutic studies of camel mange in fafan zone, eastern ethiopia. | camel mange is an economically important parasitic disease affecting productivity in camel rearing areas of the world if appropriate treatment is not instituted. | 2015 | 26627056 |
| a case of crusted scabies combined with bullous scabies. | scabies is a contagious skin disease that causes extremely itching. it is a parasitic disease caused by the mite sarcoptes scabiei and characterized by polymorphous lesions. vesicular and bullous lesions in cases of scabies are rather rare. bullous scabies has a pemphigoid presentation. crusted scabies, also known as norwegian scabies, is a rare and severe form of the disease. the large number of mites present in and on the skin cause scabies to be highly contagious. the present study reports a ... | 2015 | 26622520 |
| mechanism for transport of ivermectin to the stratum corneum in rats. | ivermectin (ivm) is used as an oral medication for scabies, a skin infection caused by a mite, sarcoptes scabiei, which parasitizes in the stratum corneum. after oral administration ivm is absorbed from the intestine, and finally distributed to the stratum corneum to eliminate the mites. however its transport mechanism remains unclear. a pharmacokinetic study was performed using hairless wistar yagi (hwy) rats, which have no or atrophied sebaceous glands, and wistar rats as a reference. after or ... | 2015 | 26613804 |
| scabies incognito presenting as a subcorneal pustular dermatosis-like eruption. | scabies is a common parasitosis of the skin caused by sarcoptes scabiei hominis. this infestation occurs in all geographic areas and across all age groups, races, and social classes. poor economic conditions and lack of proper hygiene are risk factors for the disease. subcorneal pustular dermatosis is characterized by numerous relapsing pustular eruptions on normal or mildly erythematous skin. the pustular eruption typically involves the flexural sites of the trunk and proximal extremities with ... | 2015 | 26470936 |
| a case report of crusted scabies in an adult patient with down syndrome. | crusted (norwegian) scabies is a severe manifestation of the contagious skin infection caused by sarcoptes scabiei. crusted scabies has been well described in patients with known immunocompromised states. treatment may be complicated by delayed diagnosis and/or inadequate treatment. this infection may not rank highly on one's differential diagnosis in the absence of an immunocompromised state, highlighting the uniqueness of the case being presented. several papers describe immunocompromised chil ... | 2015 | 26437167 |
| the efficacy of oral ivermectin vs. sulfur 10% ointment for the treatment of scabies. | human scabies is caused by an infection of the skin by the human itch mite (sarcoptes scabiei var. hominis). there are different medications for the treatment of scabies. this study aimed at comparing the efficacy and safety of oral ivermectin vs. sulfur 10% ointment for the treatment of scabies. in total, 420 patients with scabies were enrolled, and randomized into two groups: the first group received a single dose of oral ivermectin 200 μg/kg body weight, and the second group received sulfur 1 ... | 2015 | 26342502 |
| sarcoptes scabiei mites in humans are distributed into three genetically distinct clades. | scabies is an ectoparasitic infestation caused by the mite sarcoptes scabiei. currently, s. scabiei is taxonomically divided into different varieties on the basis of host origin. genetics-based research on scabies has been conducted, but the data on genetic diversity of populations of this mite in humans in europe are lacking. we evaluated the genetic diversity of populations of s. scabiei. a large series of mites obtained from humans in france and the data of mites from various hosts and geogra ... | 2015 | 26278670 |
| efficacy assessment of biocides or repellents for the control of sarcoptes scabiei in the environment. | sarcoptes scabiei infection is a contagious disease affecting both humans and animals. the transmission occurs either by direct contact or from the environment where mites could survive several days remaining infective. the number of products available for environmental control of s. scabiei is very limited. the objective of the present study was to assess the efficacy of biocides or repellents against s. scabiei var suis. | 2015 | 26259713 |
| evaluation of a commercial elisa for the detection of antibodies to sarcoptes scabiei in wild boar (sus scrofa). | sarcoptic mange occurs in free-ranging wild boar (sus scrofa) but has been poorly described in this species. we evaluated the performance of a commercial indirect enzyme-linked immunosorbent assay (elisa) for serodiagnosis of sarcoptic mange in domestic swine when applied to wild boar sera. we tested 96 sera from wild boar in populations without mange history ("truly noninfected") collected in switzerland between december 2012 and february 2014, and 141 sera from free-ranging wild boar presentin ... | 2015 | 26161723 |
| bullous scabies: a case report and review of the literature. | scabies is a common parasitic infection caused by the mite sarcoptes scabiei. about 300 million cases of scabies are reported annually. scabies usually presents clinically with an erythematous excoriated papulovesicular rash, burrows, nodules and hyperkeratotic lesions in specific body areas. a rare presentation of scabies is the bullous pemphigoid-like bullous scabies. so far, to the best of our knowledge, only 32 cases of bullous scabies have been reported in medical literature, of which only ... | 2015 | 26092057 |
| treatment of mange infection in a weaner flock of sheep with ivermectin at sheep breeding farm hardishiva of kashmir valley. | an outbreak of sarcoptes scabiei mange occured in a weaner flock that comprised of 74 animals including 31 male and 43 female at sheep breeding farm hardishiva of kashmir valley. all the animals in the flock were affected. animals were very weak and emaciated skin lesions were confined to the lips, nostrils, ears, face, and were characterized by pruritus, erythema, papule formation, alopecia and scab formation. microscopic examination of skin scraping revealed s. scabiei mange infestation. the a ... | 2015 | 26063994 |
| in vitro acaricidal activity of 1,8-cineole against sarcoptes scabiei var. cuniculi and regulating effects on enzyme activity. | 1,8-cineole found in many essential oils is a monoterpene and acts as a repellent against sarcoptes scabiei var. cuniculi. in the present study, the acaricidal activity of 1,8-cineole against s. scabiei var. cuniculi was evaluated and the acaricidal mechanism was also investigated by assaying enzyme activities. the results showed that the lethal concentration of 50% (lc50) value (95% confidence limit (cl)) and the lethal time of 50% (lt50) value (95% cl) of 1,8-cineole were 2.77 mg/ml and 3.606 ... | 2015 | 25924796 |
| development of conventional and real-time quantitative pcr assays for diagnosis and monitoring of scabies. | scabies remains the most prevalent, endemic, and neglected ectoparasitic infestation globally and can cause institutional outbreaks. the sensitivity of routine microscopy for demonstration of sarcoptes scabiei mites or eggs in skin scrapings is only about 50%. except for three studies using conventional or two-tube nested pcr on a small number of cases, no systematic study has been performed to improve the laboratory diagnosis of this important infection. we developed a conventional and a real-t ... | 2015 | 25903566 |
| an elderly long-term care resident with crusted scabies. | crusted scabies is a highly contagious form of scabies. altered immune response, nutritional deficiencies and modified host response are all risk factors for crusted scabies. the authors report a case involving a patient found to have a chronic maculopapular, erythematous rash with large hyperkeratotic, white and grey plaques on the soles of both feet. an ultimate diagnosis of crusted scabies was reached after a delay in diagnosis suspected to be caused by the similarity in appearance to more co ... | 2017 | 25798153 |
| superficial fibrin thrombi … and other findings: a review of the histopathology of human scabietic infections. | cutaneous infection with the mite sarcoptes scabiei var. hominis is associated with epidermal and dermal changes. after noting superficial fibrin thrombi in two biopsies with scabies mites, we comprehensively reviewed the histopathologic findings in scabietic infections to determine the frequency of this finding. | 2015 | 25754497 |
| prospective study in a porcine model of sarcoptes scabiei indicates the association of th2 and th17 pathways with the clinical severity of scabies. | understanding of scabies immunopathology has been hampered by the inability to undertake longitudinal studies in humans. pigs are a useful animal model for scabies, and show clinical and immunologic changes similar to those in humans. crusted scabies can be readily established in pigs by treatment with the glucocorticoid dexamethasone (dex). | 2015 | 25730203 |
| [scabies as an occupational disease]. | scabies is an infectious skin disease caused by the human itch mite (sarcoptes scabiei var. hominis). it is mainly transmitted by direct skin-to-skin contact. the spread of scabies can cause major difficulties in healthcare institutions, particularly in residential homes for the elderly. the disease is characterized by intense nocturnal itching, erythematous papules arranged in a linear order, and scratching resulting in excoriations. the diagnosis is confirmed by identification of the mite or b ... | 2015 | 25676574 |
| sarcoptic mange in captive maras: the first known outbreak and complete recovery with colony-wide acaricide treatment. | among 16 maras housed as a colony at a zoo, 2 initially showed generalized dermal lesions on the legs, head and abdomen. approximately 1 month later, following completion of therapy with amitraz, 6 maras in the same colony, including the 2 previously diseased animals, showed dermal lesions with severe alopecia and crusting. sarcoptic mange was diagnosed on skin scrapings on the basis of morphological criteria. the mites were highly mobile and abundant in all cases, and no other causative agents ... | 2015 | 25648673 |
| study on mange mite of camel in raya-azebo district, northern ethiopia. | a cross-sectional study was carried out to determine the prevalence and species of camel mange mite infestation in raya-azebo district, northern part of ethiopia. accordingly, three hundred and eighty-four camels were examined and mange mite infestation was detected on 64 of camels. only sarcoptes scabiei var. cameli was identified as the only mite species in all skin scraping samples collected from the suspected mange mite lesions. there was significant difference in the prevalence of mange mit ... | 2014 | 25568694 |
| assessment of the cytokine profile in peripheral blood mononuclear cells of naturally sarcoptes scabiei var. canis infested dogs. | the mechanism of cytokine secretion from t lymphocytes plays an important role in the immune response of dogs and parasitic skin infestations. assessment of the cytokine profile of naturally s. scabiei var. canis infested dogs could augment understanding of the pathobiology of canine sarcoptic mange. therefore, the present study examined the cytokines in peripheral blood mononuclear cells of dogs suffering from sarcoptic mange. thirteen dogs naturally infected with sarcoptic mange participated i ... | 2014 | 25468023 |
| exodus of sarcoptes scabiei var. hominis from the threatening blade of homo sapiens. | | 2014 | 25437988 |
| inefficacy of alcohol-based hand rub on mites in a patient with hyperkeratotic scabies. | the world health organization is strongly promoting alcohol-based hand rubs to interrupt transmission of pathogens within the healthcare environment, and in some hospitals they are being recommended in cases of scabies. however, there are no studies that demonstrate the efficacy of such hand rubs against scabies. | 2015 | 25251891 |
| detailed analysis of in vivo reflectance confocal microscopy for sarcoptes scabiei hominis. | | 2015 | 25211585 |
| [diagnosis and evolution of scabies]. | human scabies is an ectoparasitosis affecting any individual at any age. the level of infestation by sarcoptes scabiei var. hominis is influenced by any defect in immune response. several clinical types of scabies are described including baby scabies, profuse scabies of immunodepression, norvegian scabies and sarcoptic mange. onchocerciasis dermatitis is a tropical microfilariosis completely distinct by its parasitic nature. | 2015 | 25158389 |
| autoantibodies to iron-binding proteins in pigs infested with sarcoptes scabiei. | despite the availability of effective treatments, sarcoptes scabiei remains a major health problem in the pig industry. unsuccessful control of the disease is often due to the lack of reliable detection methods, with current tests relying on skin scrapings and crude antigen elisas. a previous analysis of antigens in pig skin scrapings reported that anti-transferrin antibodies were present in s. scabiei infected animals and that this finding might be considered as a useful diagnostic tool. this p ... | 2014 | 25085772 |