| [further investigations to differentiate ibr-virus from ipv-virus by the carrier-free zone electrophoresis in a glucose density gradient]. | | 1972 | 4344145 |
| characteristics and viral susceptibility of an embryo cell line from marmosa mitis. | | 1972 | 4344268 |
| interferon in nasal secretions and sera of calves after intranasal administration of avirulent infectious bovine rhinotracheitis virus: association of interferon in nasal secretions with early resistance to challenge with virulent virus. | calves which had received avirulent infectious bovine rhinotracheitis virus (av-ibr) by intranasal (in) administration developed detectable levels of interferon (if) in nasal secretions as early as 40 hr later. peak titers (1:640) of if appeared in secretions 72 to 96 hr after administration of virus, and titers of 1:80 to 1:320 were maintained through the 8th day. lower titers (1:5 to 1:10) of if were detected in sera obtained on the 4th to 8th days after administration of virus. peak titers of ... | 1972 | 4344393 |
| comparison of the biological, biophysical and antigenic properties of four strains of infectious bovine rhinotracheitis herpesvirus. | | 1972 | 4346155 |
| pathogenesis of meningo-encephalitis produced in calves by infectious bovine rhinotracheitis herpesvirus. | | 1972 | 4346156 |
| electron microscopic studies on the development of infectious bovine rhinotracheitis virus in bovine kidney cells. | | 1972 | 4346653 |
| [serological follow-up test on para-influenza-3-virus, chlamydia, coxiella burneti and ibr-virus antibodies, in a calf fattening farm]. | | 1973 | 4348166 |
| role of cell-mediated immunity in the recovery of cattle from primary and recurrent infections with infectious bovine rhinotracheitis virus. | when cattle infected with infectious bovine rhinotracheitis virus (ibrv) were treated 3 months later with a synthetic corticosteroid, consistent recrudescence of the infection was observed. suppression of cell-mediated immunity, as measured by lymphocyte transformation responses, could be demonstrated at the time of recrudescence. treatment with adrenocorticotropic hormone and trigeminal neurotomy also resulted in recrudescence of ibrv, but immunosuppression was not detected in these animals. th ... | 1973 | 4355136 |
| [modification of a strain of the bovine rhinotracheitis virus and study of its immunogeneity]. | | 1974 | 4364109 |
| an electron microscopic study of a single-cycle infection of madin-darby bovine kidney cells by infectious bovine rhinotracheitis virus. | | 1973 | 4365277 |
| replication of temperature sensitive mutant of infectious bovine rhinotracheitis virus in the tissues of inoculated calves. | | 1974 | 4365289 |
| pathogenesis of infectious bovine rhinotracheitis (ibr) virus infection in bovine fetal tracheal organ cultures. | | 1974 | 4365519 |
| virus, the primordial parasite, and man. | | 1974 | 4366090 |
| isolation of infectious bovine rhinotracheitis virus from feces of a feeder steer. | | 1974 | 4367200 |
| [study of infection in primary calf kidney cells by infectious bovine rhinotracheitis virus (ibr) using immunofluorescence]. | | 1972 | 4367470 |
| the control of mastitis. | | 1974 | 4367502 |
| the pathogenesis of recurrent infections with infectious bovine rhinotracheitis virus induced in calves by treatment with corticosteroids. | | 1974 | 4367654 |
| ibr virus isolated from two epizootics in mexican dairy cattle. | | 1974 | 4367740 |
| [incidence of antiboides against viruses of infectious bovine rhinotracheitis (ibr), parainfluenza (pi-3) and mucosal disease (vdv) in young cattle herds in the region of south western slovakia]. | | 1972 | 4367769 |
| in vivo and in vitro properties of a temperature sensitive mutant of infectious bovine rhinotracheitis virus. | | 1974 | 4368802 |
| observations and comments on two outbreaks of abortion associated with ibr virus infection. | | 1974 | 4370232 |
| observations on experimental infection with infectious bovine rhinotracheitis virus in rabbits. | | 1973 | 4370233 |
| host responses to infectious bovine rhinotracheitis virus. iii. isolation and immunologic activities of bovine t lymphocytes. | | 1974 | 4370600 |
| the general febrile respiratory form of infectious bovine rhinotracheitis in calves. | | 1974 | 4371013 |
| vaccination against infectious bovine rhinotracheitis may hamper export trade in breeding cattle. | | 1974 | 4371120 |
| development of intranasal vaccination for the immunization of cattle against infectious bovine rhinotracheitis. | | 1974 | 4371209 |
| rational basis for an immunization program against the common diseases of the bovine respiratory tract. | | 1974 | 4371397 |
| [demonstration of the ibr-ipv virus in the vaginal secretion of cows with vulvovaginitis]. | | 1973 | 4371413 |
| electron microscopic observations on infectious bovine rhinotracheitis virus in bovine fetal tracheal organ cultures. | | 1974 | 4371686 |
| differentiation of strains of infectious bovine rhinotracheitis virus by neutralization kinetics with late 19s rabbit antibodies. | two vaccine, two respiratory (infectious bovine rhinotracheitis [ibr]), and two genital (infectious pustular vulvovaginitis [ipv]) strains of infectious bovine rhinotracheitis virus were compared by neutralization kinetics using late 19s antibody (ab). the two vaccine strains were indistinguishable from one another, but were neutralized far more rapidly than the other four strains when either anti-ibr or anti-ipv 19s ab was used. the two ipv strains were indistinguishable from one another, but w ... | 1974 | 4372173 |
| an indirect haemagglutination test for the detection and assay of antibody to infectious bovine rhinotracheitis virus. | | 1974 | 4372777 |
| a field trial to evaluate an intranasal infectious bovine rhinotracheitis vaccine. | | 1974 | 4373161 |
| experiments on the effectiveness of inactivatedd infectious bovine rhinotracheitis vaccine. | | 1974 | 4373296 |
| immunization of cattle with an attenuated ibr vaccine. | | 1974 | 4373298 |
| vaccination of calves against infectious bovine rhinotracheitis using a temperature senstive mutant. | | 1974 | 4373299 |
| vulvovaginitis in wildebeest caused by the virus of infectious bovine rhinotracheitis. | | 1974 | 4373588 |
| complement-requiring neutralizing antibodies in cattle to infectious bovine rhinotracheitis virus. | | 1974 | 4374159 |
| infectious bovine rhinotracheitis virus and its role in bovine abortion. | | 1974 | 4374672 |
| [comparative study on the sensitivity of pk cell line, hela cells and primary piglet kidney cells to infection with infectious bovine rhinotracheitis-infectious pustular vulvovaginits of virus of cattle (ibr - ipv)]. | | 1974 | 4374788 |
| [use of micro-plaque fluorescence method for the study of infection of primary kidney cells by infectious bovine rhinotracheitis virus]. | | 1974 | 4375331 |
| isolation of mycoplasma agalactiae var bovis and infectious bovine rhinotracheitis virus from an outbreak of mastitis in france. | | 1974 | 4375340 |
| membrane concentration of infectious bovine rhinotracheitis virus from water. | a membrane adsorption procedure was used to concentrate infectious bovine rhinotracheitis virus from 1-liter quantities of distilled water. cellulose nitrate membrane filters (0.45-mum pore size) efficiently adsorbed this herpesvirus from water, and virus was recovered from the membrane by elution with 10 ml of fetal calf serum during sonic treatment. the average recovery rate was 70%. | 1974 | 4375434 |
| assay and antigenic interrelationships of the recently isolated bovine herpesviruses, dn599, ftc, and v11. | | 1974 | 4375445 |
| infectious bovine rhinotracheitis virus in extended bovine semen 1. | | 1973 | 4377939 |
| the use of the micro-modified direct-cf-test in the detection of ibr and bvd antibodies. | | 1973 | 4377947 |
| virus isolations from cases of infectious bovine pustlo-vulvovaginitis and posthitis (ipv/ipb) in cattle in tanzania. | | 1974 | 4378003 |
| the incidence of infectious bovine rhinotracheitis antibody in tanzanian game animals and cattle. | | 1974 | 4378007 |
| replication of infectious bovine rhinotracheitis virus in calf kidney cells studied by immuno- and acridine orange-fluorescence. | | 1970 | 4394991 |
| host defense mechanisms against infectious bovine rhinotracheitis virus: in vitro stimulation of sensitized lymphocytes by virus antigen. | isolated peripheral blood lymphocytes (pbl) from cattle immunized or infected with infectious bovine rhinotracheitis (ibr) virus were cultured in vitro with ultraviolet light-inactivated ibr virus, and the degree of lymphocyte blastogenesis was quantitated by measurement of the uptake of [(3)h]thymidine into acid-insoluble material. lymphocyte blastogenesis only occurred with pbl from immunized or infected animals. the optimal conditions for lymphocyte blastogenesis were defined. blastogenesis w ... | 1974 | 4426702 |
| infectious bovine rhinotracheitis virus infection in bulls, with special reference to preputial infection. | in an experiment with infectious bovine rhinotracheitis (ibr) virus in two bulls, observed over a period of 122 weeks, the pattern of virus release was studied. recurrent, unprovoked release of virus was demonstrated after one year in a nasal washing from one of the bulls and in preputial washings of both on 13 and 4 occasions, respectively, and finally in weeks 113 and 110, although clinical disease was not observed. during periods of recurrent virus release, concentrations of virus in the prep ... | 1973 | 4751790 |
| letter: the use of corticosteroids to aid detection of bulls carrying infectious bovine rhinotracheitis virus. | | 1973 | 4777219 |
| the breeding record of cows inseminated with a batch of semen contaminated with infectious bovine rhinotracheitis virus. | | 1973 | 4784189 |
| infectious bovine rhinotracheitis virus recovered from the milk of a cow with mastitis. | | 1974 | 4813530 |
| an outbreak of abortion in a dairy herd following inoculation with an intramuscular infectious bovine rhinotracheitis virus vaccine. | | 1974 | 4831374 |
| method for studying particle size and infective potential of infectious bovine rhinotracheitis virus aerosols. | | 1971 | 4925536 |
| growth of infectious bovine rhinotracheitis virus in organ cultures. | | 1968 | 5660994 |
| comparative studies of strains of infectious bovine rhinotracheitis virus isolated from latently infected calves. | three strains (479 c, 778 tl, 982 le) of infectious bovine rhinotracheitis (ibr) virus isolated from latently infected calves were compared with the prototype strain of ibr virus (la strain) in studies which included restriction endonuclease analysis, experimental infection, and reciprocal cross protection tests in cattle. from the restriction endonuclease analysis it appeared that the 3 "latent" viruses were derived from the same isolate, and that it differed slightly from the la strain. howeve ... | 1984 | 6086223 |
| serologic cross-reaction between bovine herpesviruses 1 and 4 by the enzyme-linked immunosorbent assay. | reciprocal cross-titrations using constant concentrations of bovine antiserum (1: 100) to either bovine herpesvirus (bhv) 1 or bhv 4 (obtained from controlled infection status) against varying concentrations of both viral antigens in enzyme-linked immunosorbent assay (elisa) indicated a subtle difference between the antigenic composition of these 2 agents. although control antiserum consistently yielded higher elisa titers against homologous viral antigen, a considerable cross-reactivity between ... | 1984 | 6087088 |
| prevalence of antibodies to bovine respiratory syncytial virus, bovine viral diarrhea virus, bovine herpesvirus-1, and bovine parainfluenza-3 virus in sheep and goats in quebec. | serum samples were collected from 1,075 clinically normal sheep and goats from 77 flocks in 7 agricultural regions of quebec from june to august 1982. sheep and goats were tested for antibodies to bovine respiratory syncytial virus, bovine viral diarrhea virus, and bovine herpes-virus-1 by the indirect fluorescent antibody technique and for parainfluenza-3 virus by the hemagglutination inhibition test. the prevalence of antibodies in animals to respiratory syncytial virus was 31%; to bovine vira ... | 1984 | 6089626 |
| the possible role of stress in the induction of pneumonic pasteurellosis. | five groups of range bred calves (four calves per group) were used to investigate the effect of stress on susceptibility to aerosol exposures with bovine herpesvirus-1 or pasteurella haemolytica. twelve calves were weaned, transported, processed at a commercial feedlot and transported to isolation facilities three days later. an aerosol challenge of either 10 colony forming units of p. haemolytica or 10 plaque forming units of bovine herpesvirus-1 virus was given to two groups of calves and the ... | 1984 | 6089981 |
| effect of levamisole and bovine interferon alpha 1 on bovine immune responses and susceptibility to bovine herpesvirus-1. | | 1984 | 6091152 |
| antibody-dependent cell-mediated cytotoxicity against ibr-infected bovine kidney cells by ruminant neutrophils: the role of lysosomal cationic protein. | antibody-dependent cell-mediated cytotoxicity (adcc) of infectious bovine rhinotracheitis (ibr)-infected bovine kidney cells (mdbk) by neutrophils was demonstrated. neutrophils from bovine and sheep mammary exudate and peripheral blood, and also from human peripheral blood, were all active in the presence of anti-ibr antibody. the component of the ruminant neutrophil granules which was responsible for cytotoxicity appeared to be cationic protein since purified cationic protein lysed the virus-in ... | 1984 | 6092270 |
| the antiviral spectrum of (e)-5-(2-bromovinyl)-2'-deoxyuridine. | the antiviral activity spectrum of (e)-5-(2-bromovinyl)-2'-deoxyuridine (bvdu) is not restricted to herpes simplex virus type 1 (hsv-1) and varicella-zoster virus (vzv) but also encompasses several other herpesviruses such as suid herpesvirus type 1 (shv-1), bovid herpesvirus type 1 (bhv-1), simian varicella virus (svv), herpesvirus saimiri, herpesvirus platyrrhinae, and the baculovirus trichoplusia ni multiple nuclear polyhedrosis virus. other herpesviruses such as herpes simplex virus type 2, ... | 1984 | 6092320 |
| failure to demonstrate infectious bovine rhinotracheitis virus reactivation in parturient cows. | | 1984 | 6093324 |
| the effect of some common inactivation procedures on the antigens of bovine herpesvirus 1. | bovine embryonic kidney cells were infected with bovine herpesvirus 1 (bhv1) or were sham-inoculated. when cytopathic effect was apparent, the cells were treated with beta-propiolactone, formalin, heat (56 degrees c), or ultraviolet irradiation until the virus was inactivated. infected-treated, infected-untreated (iu) and sham-inoculated cultures were solubilized using triton x-100 detergent. resulting preparations were tested by 2-dimensional- and fused rocket-immunoelectrophoresis and were eva ... | 1984 | 6093334 |
| bovine interleukin 2 (il-2) production and activity on bovine and murine cell lines. | long-term growth of t cell cultures requires addition of interleukin 2 (il-2). in order to maintain bovine cultures, optimal conditions for bovine il-2 production were defined using peripheral blood mononuclear cells (pbm). irradiation and preculture enhanced il-2 production possibly by reducing suppressor activity. il-2 activity was also detected in bovine herpesvirus type 1-stimulated cultures. unlike mitogen-stimulated cultures, a wide variation in il-2 activity was seen between supernatants ... | 1984 | 6093342 |
| in utero infection of swine fetuses with infectious bovine rhinotracheitis virus (bovine herpesvirus-1). | the pathogenesis of infectious bovine rhinotracheitis (ibr) virus (bovine herpesvirus-1) was studied in porcine fetuses after in utero inoculation. laparotomies were performed on 8 seronegative pregnant sows at 34 to 86 days of gestation, and all fetuses in 1 uterine horn of each sow were exposed to ibr virus via inoculation into the amniotic sacs. fetuses in the other horn served as controls. clinical signs of infection were not observed in the sows, except for 2 sows that aborted at postinocul ... | 1984 | 6093638 |
| meningoencephalitis in calves due to bovine herpesvirus type 1 infection. | | 1984 | 6093760 |
| specificity of pseudorabies virus serotests. | pigs experimentally inoculated with bovine herpesvirus-1 or equine herpesvirus-1 developed mild clinical disease signs. regression of clinical disease was accompanied by development of specific virus-neutralizing antibodies. these antibodies did not react positively with pseudorabies antigens in the serum-virus neutralization test, an indirect radioimmunoassay, or a microimmunodiffusion test. | 1984 | 6098206 |
| [infectious bovine rhinotracheitis virus (bovine herpesvirus l): biochemical aspects]. | the biochemical characteristics of infectious bovine rhinotracheitis virus (bovine herpes-virus 1, bhv 1) are reviewed: description of the virion particle and virus purification, analysis of structural and non structural proteins, nucleic acid properties, restriction endonuclease analysis of the viral dna. the authors emphasize the biochemical methods able to insure a better understanding of the molecular epidemiology of bhv 1 and of its latency; also to develop biochemical weapons against the i ... | 1984 | 6099078 |
| [infectious bovine rhinotracheitis (vhb-1). ii. physico-chemical properties of strain l-114]. | the thermal stability, density gradient and morphological features of a recently isolated l-114 strain of infectious bovine rhinotracheitis virus were determined. morphology studies showed an enveloped virus with 200 nm of total diameter, a core diameter of 90 nm and an icosaedral-type structure; purified preparations contained both complete and empty viral particles. more than 90% of the infectivity was lost after 15 hours at 37 degrees c; at 56 degrees c, inactivation was much faster, with a 3 ... | 1982 | 6100998 |
| [standardization of a microtechnic for passive hemagglutination to detect antibodies against infectious bovine rhinotracheitis]. | a micromethod for passive hemagglutination is described for the detection of ibr antibodies in serum samples of nine herds. the samples correspond to different zones of the province buenos aires. in animals without clinical signs the proportion of positives was 43.60%; in herds with signs consistent with the disease, this value attained 66.4% positivity (tables 1 and 2). the feasibility of this method is discussed. some variants introduced into the original technique are described. | 1984 | 6101039 |
| serological evidence of some bovine viruses in the caribou (rangifer tarandus caribou) in quebec. | | 1981 | 6121921 |
| serologic survey for selected microbial pathogens in alaskan wildlife. | antibodies to brucella spp. were detected in sera of seven of 67 (10%) caribou (rangifer tarandus), one of 39 (3%) moose (alces alces), and six of 122 (5%) grizzly bears (ursus arctos). antibodies to leptospira spp. were found in sera of one of 61 (2%) caribou, one of 37 (3%) moose, six of 122 (5%) grizzly bears, and one of 28 (4%) black bears (ursus americanus). antibodies to contagious ecthyma virus were detected in sera of seven of 17 (41%) dall sheep (ovis dalli) and five of 53 (10%) caribou ... | 1983 | 6139490 |
| neutrophils in antiviral immunity: inhibition of virus replication by a mediator produced by bovine neutrophils. | neutrophils collected from bovine mammary glands were placed in culture with virus-infected cell preparations that had been inactivated by ultraviolet light. upon culture with infectious bovine rhinotracheitis (ibr) virus-infected georgia bovine kidney cells, a material was released from the neutrophils that, like interferon, inhibited the replication of vesicular stomatitis virus and ibr virus. cell-free ibr virus was a less effective inducer of the inhibitor produced by neutrophils. other herp ... | 1980 | 6154112 |
| protection of calves against rhinovirus infection by nasal secretion interferon induced by infectious bovine rhinotracheitis virus. | | 1980 | 6154436 |
| [isolation of the ibr virus antigen for immunodiffusion]. | a number of physicochemical and immunoelectrophoretic investigations as well as tests were carried out for the standardization of an antigen for immunodiffusion prepared from an ibr virus. the antigen showed strict specificity and maximum activity at a concentration forming a 7.5-8.0 mm diffusion disc in a radical immunodiffusion. it is made up of two antigenic components and shows a pronounced lability. the antigen reacts more intensely with immunoglobulins of the igm type but is also active wi ... | 1980 | 6164151 |
| [induction of interferon activity in nasal mucus by association of levamisole by systemic route -- inactivated virus by local route (author's transl)]. | calf respiratory disease could have a non-specific origin. the respiratory tract bacterial flora is pathogen only if the animal faces stress which decreases the defense capacities of the respiratory mucosa. the simultaneous administration of uv irradiated ibr virus by nasal route and of levamisole by systemic route induces a protection which is accompanied by interferon synthesis in the nasal mucus. this protection is evaluated experimentally with an infectious ibr virus challenge. in the natura ... | 1980 | 6167194 |
| the local and systemic immune response of calves following experimental infection with i.b.r. virus. | | 1981 | 6174038 |
| levamisole and bovine immunity: in vitro and in vivo effects on immune responses to herpesvirus immunization. | levamisole was shown to enhance in vitro blastogenic responses of bovine lymphocytes to nonspecific mitogens (phytohemagglutinin and pokeweed mitogen) as well as to infectious bovine rhinotracheitis virus and purified protein derivative. greatest enhancement was observed at suboptimal concentrations of viral antigen. in addition to enhancing lymphocyte reactivity levamisole also affected macrophage activity as determined by increased fc receptor activity and [3h]glucosamine incorporation. levami ... | 1981 | 6174193 |
| susceptibility of bovine macrophages to infectious bovine rhinotracheitis virus infection. | infectious bovine rhinotracheitis virus replicated in cultured bovine alveolar macrophages (am). however, yields of infectious virus were low, with maximum titers approximately 100 times that of the residual inoculum. immunofluorescence and electron microscopic studies indicated that the majority of macrophages produced viral antigen, but after infection at a multiplicity of 0.1, only 4.1% of am produced infectious centers. virus-infected am culture supernatants possessed interfering activity, p ... | 1982 | 6175574 |
| duration of protection of calves against rhinovirus challenge exposure by infectious bovine rhinotracheitis virus-induced interferon in nasal secretions. | six calves inoculated intranasally with a vaccinal strain of infectious bovine rhinotracheitis (ibr) virus and 6 control calves were given a placebo. all calves were subsequently challenge exposed (by aerosol) with rhinovirus--3 of the calves from each group at 2 days after they were inoculated with ibr virus or with placebo and the remaining calves at 6 days. nasal excretion of viruses, interferon (ifn) concentrations in nasal secretions (ns), and neutralizing antibody in sera and ns were deter ... | 1982 | 6178325 |
| temporary protection of calves against adenovirus infection by nasal secretion interferon induced by infectious bovine rhinotracheitis virus. | | 1982 | 6179442 |
| partial protection of calves against parainfluenza-3 virus infection by nasal-secretion interferon induced by infectious bovine rhinotracheitis virus. | | 1982 | 6179445 |
| protection against experimental infection of calves vaccinated intranasally by three attenuated strains of ibr virus. | | 1982 | 6183846 |
| bovine herpesvirus-1 vaccination against experimental bovine herpesvirus-1 and pasteurella haemolytica respiratory tract infection: onset of protection. | the onset of protection offered by intranasal vaccination with attenuated bovine herpesvirus-1 (bhv-1) was studied in 18 calves given a virulent bhv-1 aerosol challenge inoculum and an aerosol challenge exposure to pasteurella haemolytica. calves challenge exposed with virus 3, 7, 11, 15, or 19 days after vaccination and challenge exposed 4 days later with pasteurella haemolytica did not develop viral-bacterial pneumonia, whereas 2 of 3 control calves died of fibrinous bronchopneumonia 40 and 60 ... | 1982 | 6183996 |
| [interferon induction in calves after experimental infection with bovine herpesvirus 1]. | a total of 9 calves were used to test the interferon-inducing activity of strain vulchedrum of the bovid herpes virus 1. the virus of stomatitis vesiculosa adapted to cell cultures of calf kidney was used as an indicator of interferon. the antiviral action of interferon was demonstrated in the serum and the nose discharge of calves. the dynamics of interferon production in calves varied, depending on the venous, muscular, and tracheal route of application of the virus. highest interferon titer i ... | 1982 | 6188269 |
| ocular disease in red deer calves associated with a herpesvirus infection. | | 1983 | 6194610 |
| antiviral effects of bovine interferons on bovine respiratory tract viruses. | the antiviral effects of bovine interferons on the replication of bovine respiratory tract viruses were studied. bovine turbinate monolayer cultures were treated with bovine interferons and challenged with several bovine herpesvirus 1 strains, bovine viral diarrhea virus, parainfluenza type 3 virus, goat respiratory syncytial virus, bovine respiratory syncytial virus, bovine adenovirus type 7, or vesicular stomatitis virus. treatment with bovine interferons reduced viral yield for each of these ... | 1984 | 6201505 |
| neutralizing determinants defined by monoclonal antibodies on polypeptides specified by bovine herpesvirus 1. | monoclonal antibodies were used to study neutralizing determinants on polypeptides of bovine herpesvirus 1. two of three monoclonal antibodies which recognized nonoverlapping epitopes on a glycoprotein of 82,000 daltons were found to neutralize. a second group of monoclonal antibodies that individually precipitated five viral glycopolypeptides ranging in size from 102,000 to 55,000 daltons also neutralized. two monoclonal antibodies which were the most efficient in neutralization recognized a no ... | 1984 | 6208375 |
| cross-reactions of bovine herpesvirus 1 antigens with those of other cattle herpesviruses. | bovine embryonic kidney cells were infected with bovine herpesviruses (bhv1, 2, or 3), suid herpesvirus 1 (shv1), or were sham-inoculated. when cytopathic effect was apparent, the cells were solubilized using triton x-100 detergent. resulting antigen preparations were tested by 2-dimensional immunoelectrophoresis using bovine fetal serum and antisera directed against bhv1, bhv2, bhv3, shv1 or a restricted spectrum of bhv1 antigens. interaction of bhv1 antiserum with bhv1 antigen preparations res ... | 1984 | 6208673 |
| mechanisms of recovery from viral infections: destruction of infected cells by neutrophils and complement. | highly enriched populations of bovine neutrophils (pmn) were able to destroy herpesvirus-infected cells when in the presence of c. this mechanism of cytotoxicity was termed c-dependent neutrophil-mediated cytotoxicity (cdnc). to demonstrate cdnc required viable pmn, an active source of c, and a target cell expressing viral antigens. noninfected cells were not susceptible to lysis. several approaches were used to exclude the presence of antibody as an explanation for the cytotoxicity observed. in ... | 1980 | 6243147 |
| [slow ibr infections: a critical approach]. | | 1980 | 6243423 |
| [protective action of inactivated adjuvant ibr vaccine against experimental infection in cattle]. | | 1980 | 6243812 |
| clearance and shedding of infectious bovine rhinotracheitis virus from the nasal mucosa of immune and nonimmune calves. | infectious bovine rhinotracheitis virus was rapidly cleared from the nasal mucosa of calves after intranasal aerosol exposure. nonimmune calves (experiment 1) cleared 10(9) plaque-forming units (pfu) of virus from the nasal mucosa in less than 4 hours and 10(6) pfu of virus in 1 hour. an eclipse phase followed the clearance of viral inoculum. replicating virus was first detected at 9 hours. viral titers increased stepwise until maximum was attained on postinoculation day 4. virus persisted in th ... | 1980 | 6244760 |
| evaluation of experimental subunit vaccines for infectious bovine rhinotracheitis. | subunit infectious bovine rhinotracheitis (ibr) antigens were prepared by solubilization of ibr-virus infected cell cultures with nonionic detergents triton x-100 and np-40. when used with freund's incomplete adjuvant, triton x-100 and np-40 subunit antigens induced high serum-neutralization titers in vaccinated calves. two doses of triton x-100 and np-40 subunit vaccines prevented the appearance of clinical signs of disease in all vaccinated calves exposed 30 days after the second vaccinal dose ... | 1980 | 6245609 |
| destruction of virus infected cells by neutrophils and complement. | the paper describes an antibody independent mechanism of cytotoxicity whereby virus infected but not uninfected cells are destroyed by the combined presence of neutrophils and complement. | 1980 | 6245915 |
| a seroepidemiologic survey of three pronghorn (antilocapra americana) populations in southeastern idaho, 1975-1977. | sera from 104 adult and 42 fawn pronghorn antelope (antilocapra americana) from southeastern idaho were tested against selected livestock pathogens. the numbers positive/numbers tested (% positive) were as follows: bovine virus diarrhea - adults 2/102 (2), fawns 0/41 (0);; infectious bovine rhinotracheitis - adults 27/101 (27), fawns 9/42 (22); parainfluenza 3 - adults 79/104 (76), fawns 22/42 (52); bovine adenovirus 7 - adults 42/103 (41), fawns 20/48 (48); bovine adenovirus 3 - adults 11/32 (3 ... | 1980 | 6246285 |
| polymorphonuclear neutrophil-mediated antibody-dependent cell cytotoxicity of herpesvirus-infected cells: ultrastructural studies. | bovine polymorphonuclear neutrophils (pmn) can mediate antibody-dependent cell cytotoxicity (adcc) of herpesvirus-infected cells. since cytotoxicity occurs only in the presence of pmn and specific antiviral antibody, but not until viral membrane antigens are expressed on the target cell, it is concluded that antibody must recognize viral membrane antigens before cytotoxicity can occur. cytotoxicity also requires very close contact between the target cell and the pmn cell. these interactions occu ... | 1980 | 6247046 |
| evaluation of the rabbit as a laboratory model for infectious bovine rhinotracheitis virus infection. | experimental infection of rabbits with infectious bovine rhinotracheitis virus (ibrv) produced diverse manifestations of disease which included abortion, conjunctivitis, dermatitis, vulvovaginitis, systemic infection, neonatal death and respiratory tract infection. each disease syndrome was studied using virus isolation, fluorescent antibody examination and histologic examination. conjunctivitis, dermatitis and vulvovaginitis lesions were characterized by edema, infiltration of mucosa and submuc ... | 1980 | 6247121 |