| experimental pseudomonas infection in mice: acquired resistance against pseudomonas septicemia and altered susceptibility in bcg infected mice. | pseudomonas septicemia in mice caused the early death in the first three days of infection without any localized lesions. localized lesions such as abscess are observed in the kidney and liver after the third day of infection. the early death increased in the bcg infected mice showing an increased level of macrophage activation. it seemed that such early death is due to endotoxin produced by pseudomonas aeruginosa. however, the bcg infected mice showing an enhanced antibody formation were more r ... | 1978 | 362026 |
| bacteriological and clinical studies of sulbenicillin. | a new semi-synthetic penicillin, sulbenicillin, was evaluated with regard to clinical effect on infections caused by pseudomonas aeruginosa and other bacteria, serum concentrations obtained after intravenous administration and antibacterial spectrum, in comparison with the closely related antibiotic carbenicillin. the antibacterial spectra of sulbenicillin and carbenicillin were similar but the mic values were lower for sulbenicillin against most of the bacterial strains tested. the serum concen ... | 1978 | 362518 |
| comparison of three methods for identifying nonfermenting gram-negative rods. | seventy-six strains of nonfermenting gram-negative rods were tested on the analytab products, inc. (api) system and on conventional media. in addition, 51 strains were tested on the oxi-ferm system. when the identification results were compared, the api agreed with the conventional system on 41% of the isolates and oxi-ferm agreed with the conventional system on 72% of the isolates. api had the greatest difficulty in identifying pseudomonas aeruginosa. api and oxi-ferm both had difficulty identi ... | 1978 | 365307 |
| refined molecular weights for phage, viral and ribosomal rna. | the rnas of the escherichia coli bacteriophages ms2 and qbeta as well as e. coli 16s ribosomal rna were examined under identical conditions by electron microscopy using the protein-free benzyldimethylalkylammonium chloride (bac) spreading technique. from the contour length ratios of the rnas and the known number of nucleotides for ms2, the chain lengths for qbeta rna and 16s rna were found to be 4790 +/- 150 and 1645 +/- 55 nucleotides. correcting for the base composition of qbeta rna the molecu ... | 1978 | 365689 |
| empiric therapy of febrile granulocytopenic patients. | antibiotic therapy in granulocytopenic cancer patients, the risk factors predisposing these patients to infection, and the signs, symptoms and types of infections occurring in these patients are reviewed. the four most commonly isolated organism at most cancer treatment centers are escherichia coli, klebsiella spp., pseudomonas aeruginosa and staphylococcus aureus. early antimicrobial therapy with broad-spectrum antibiotics before culture results are known produces cure rates of approximately 70 ... | 1979 | 369364 |
| effects of storage in an anaerobic transport system on bacteria in known polymicrobial mixtures and in clinical specimens. | an anaerobic transport system (ats) which provides for catalytic removal of oxygen was evaluated by using in vitro-prepared polymicrobial mixtures of logphase bacteria and clinical specimens. inoculated swabs were stored at room temperature in (i) aerobic, (ii) anaerobic glove box, and (iii) ats environments, and bacteria were quantitated after 2, 24, 48, and 72 h. bacteria in a three-part mixture of bacteroides fragilis, peptostreptococcus anaerobius, and escherichia coli and in a five-part mix ... | 1978 | 370142 |
| thermosensitive h1 plasmids determining citrate utilization. | twelve thermosensitive h1 plasmids from strains of salmonella typhi that had caused outbreaks of chloramphenicol-resistant typhoid fever in vietnam, thailand and india mediated citrate utilization (cit+) in a prototrophic escherichia coli k12 strain but not in the s. typhi strains from which they were derived. four h1 plasmids from a similar outbreak in mexico differed from the far eastern plasmids in not mediating citrate utlization but in mediating mercury resistance. h1 plasmids resembling th ... | 1978 | 370344 |
| patterns of infection in untreated acute leukemia: impact of initial hospitalization. | several previous authors have examined the association between infection and acute leukemia, especially at the time of death, but none has assessed this problem at the time of diagnosis and initial hospitalization. we have undertaken a retrospective review of cases of acute leukemia diagnosed at the affiliated hospitals of the state university of new york at buffalo. results suggest that bacteriologic findings in this population initially resemble those in the general outpatient population. gram ... | 1979 | 371009 |
| a prospective controlled investigation of prophylactic trimethoprim/sulfamethoxazole in hospitalized granulocytopenic patients. | oral trimethoprim/sulfamethoxazole (tmp/smz) therapy was investigated in the prophylaxis of infections in granulocytopenia. hospitalized granulocytopenic patients were allocated at random to receive tmp/smz (group 1) or to a control group (group 2). the percentage of febrile granulocytopenic days was significantly reduced in group 1, 19 per cent compared to 39 per cent in group 2 (p less than 0.01). in group 1, there were no bacteremias in 59 episodes of granulocytopenia (909 days). in group 2, ... | 1979 | 371396 |
| identification of gram-negative non-fermenters and oxidase-positive fermenters by the oxi/ferm tube. | since the recent introduction of the roche oxi/ferm tube to the uk two identification schemes have been developed by the manufacturer for use with the kit. we evaluated the success of these two schemes in identifying 222 predominantly culture collection strains belonging to 45 taxa of non-fermenters and nine taxa of oxidase-positive fermenters. the strains were chosen to represent all the taxa included in the two identification schemes developed by the manufacturer and we have therefore been abl ... | 1979 | 372251 |
| transfer of bacterial infections by donor cornea in penetrating keratoplasty. | a 45-year-old man died of hogdkin's disease complicated by peritonitis and possible septicemia. his corneas were used for transplant in a 26-year-old man with advanced keratoconus and a 42-year-old man with vascularized central leukoma of old herpetic keratitis. both recipients developed a fulminating endophthalmitis with pseudomonas aeruginosa. we believe that the donor corneas, although clinically normal, were heavily infected, with signs of inflammation possibly suppressed by the hodgkin's di ... | 1979 | 373448 |
| investigations in mice on the potentiation of resistance to infections by a new immunostimulant compound. | bm 12.531, 2-[2-cyranaziridinyl-(1)]-2-[2-carbamoylaziridinyl-(1)]-propane, a new immunostimulant compound, increased the resistance of mice to infection with candida albicans. because bm 12.531 had no fungistatic activity in vitro, it is proposed that the therapeutic effect of bm 12.531 is caused by the stimulation of cell-mediated immunity. administration of cyclophosphamide alone increased the mortality among mice infected with c. albicans and pseudomonas aeruginosa, but when bm 12.531 was th ... | 1979 | 374647 |
| isolation of plasmodium berghei by hemolysin lysis of infected erythrocytes and evidence for a parasite hexokinase. | a rapid and simple procedure has been developed for the isolation of plasmodium berghei parasites from infected-mouse erythrocytes employing the heat stable hemolysin produced by pseudomonas aeruginosa. using parasites isolated by this method, the presence of a parasite specific hexokinase has been demonstrated, providing an explanation for the increased glucose consumption observed with infected cells. enzyme assays and serology were employed in determining the purity and yield of purified para ... | 1979 | 376819 |
| [antibacterial effect of ankerplast spray]. | the diffusion test yielded no satisfactory results. in the tube test, both the spray and the solvent (in a dilution of 1:4 and 1:8, respectively) proved to be bacteriostatically active against enterococci, staphylococcus aureus, escheria coli, proteus, and pseudomonas aeruginosa. these germs were killed within 30 minutes in the test for bactericidal activity, whereas the reference substance (1% phenol) required 1--2 hours, except against the last-named germ. even the copolymer exerted a bacteric ... | 1979 | 377580 |
| the antibody response to enterobacteriaceae and pseudomonas of patients with malignancies complicated by bacteremia. | the antibody response to the o antigens of the patients' own gram-negative bacteria causing bloodstream infection in patients with malignancies was investigated using the hemagglutination test. of the 87 patients, 42 (48%) produced specific antibodies in significant titers. differences were noted between the various microorganisms. of 44 patients with e. coli bacteremia 26 (59%) had an antibody response, whereas only 5 (33%) out of 15 subjects with pseudomonas aeruginosa infection did. the antib ... | 1979 | 377859 |
| transaminase b from escherichia coli: quaternary structure, amino-terminal sequence, substrate specificity, and absence of a separate valine-alpha-ketoglutarate activity. | transaminase b (branched-chain amino acid aminotransferase, ec 2.6.1.42), the ilve gene product, was purified to apparent homogeneity from an escherichia coli k-12 strain which carries the ilve gene both on the host chromosome and on a plasmid. the oligomeric structure of the enzyme, as determined by analytical ultracentrifugation and sodium dodecyl sulfate-polyacrylamide gel electrophoresis, was confirmed to be that of a hexamer with a molecular weight of about 182,000 and apparently identical ... | 1979 | 378964 |
| the effects of the ultraviolet-protecting plasmids pkm101 and r205 on dna polymerase i activity in escherichia coli k-12. | the mutagenesis- and repair-enhancing plasmids pkm101 and r205 were introduced into a series of esherichia coli k-12 pola mutants including two temperature-sensitive mutants. polymerase levels in extracts of these strains were assayed using an activated dna template. in none of the cases did the presence of the plasmid in the strains change either the initial rate of incorporation of [3h]thymidine triphosphate into acid-soluble material or the subsequent degradation of the template at longer rea ... | 1979 | 379622 |
| clindamycin in treatment of aspiration pneumonia in children. | twenty-eight patients with anaerobic pleuropulmonary infections were treated with clindamycin alone or clindamycin with gentamicin. sixteen of the patients presented with pneumonitis, nine with necrotizing pneumonia, and three with lung abscesses. the average length of treatment was 13.8 days, and the duration of temperature after initiation of therapy was 3.1 days. the predominant isolates were anaerobic gram-positive cocci (23 isolates), bacteroides melaninogenicus (14), bacteroides fragilis ( ... | 1979 | 380459 |
| gentamicin resistance in christchurch hospitals. | prior to june 1976, the isolation of gentamicin resistant organisms was an infrequent occurrence in north canterbury hospital board institutions. during july 1976, 20 different gentamicin resistant organisms were isolated from patients in christchurch hospital. gentamicin resistant organisms hav e been continually isolated from an increasingly wide area since then. the organisms involved are: providence species; pseudomonas aeruginosa; klebsiella species; e coli; staphyloccus aureus; proteus mir ... | 1979 | 381994 |
| [experience with sisomicin in pediatrics (author's transl)]. | sisomicin, an aminoglycoside antibiotic, is especially effective against escherichia coli, klebsiella, enterobacter, citrobacter, serratia, indole-positive and indole-negative proteus species, pseudomonas aeruginosa, salmonella and staphylococcus aureus. it has a bactericidal action. although sisomicin is similar to the other aminoglycoside antibiotics, there is not complete cross-resistance to them. our own pharmacokinetic investigations showed that a dose of 2--3 mg/kg body weight of sisomicin ... | 1979 | 383623 |
| netilmicin in the treatment of infections in patients with cancer. | ninety-two patients with cancer with 100 infectious episodes were treated with netilmicin sulfate, a new aminoglycoside. netilmicin was administered intravenously, either intermittently or by continuous infusion. the overall cure rate was 60%. gram-negative bacilli were the most common causative organisms and the response rate for these infections was 32/53 (60%). the most common pathogens were escherichia coli, klebsiella pneumoniae, and pseudomonas aeruginosa. pneumonia, urinary tract infectio ... | 1979 | 389189 |
| in vitro investigations with fosfomycin on mueller-hinton agar with and without glucose-6-phosphate. | determination of the minimal inhibitory concentration of fosfomycin in the agar dilution test on mueller-hinton agar showed that the addition of glucose-6-phosphate to the nutrient medium potentiates the action of fosfomycin against escherichia coli, klebsiella, enterobacter, citrobacter and staphylococcus aureus, sometimes by as much as 256-fold. such a potentiation of action was not detectable with serratia marcescens, the individual proteus species, pseudomonas aeruginosa or enterococci. fosf ... | 1979 | 389806 |
| nonfermentative bacilli: evaluation of three systems for identification. | three systems for the identification of nonfermentative bacilli were evaluated for their rapidity and accuracy of identification of 217 strains. two of the systems, api 20e (api) and oxi/ferm tube (oxif), are available as kits; the oxidative attack (oa) system is not commerically available. the overall accuracies of the oa, api, and oxif systems were 91, 69, and 50%, respectively. identification within 48 h was achieved for 98% of the strains by oa, for 50% by api, and for 18% by oxif. most of t ... | 1979 | 389945 |
| bacteriologic considerations in perforated necrotizing enterocolitis. | during a ten-year period, 61 infants with perforated necrotizing enterocolitis were managed by bowel resection, enterostomy, and intravenous antibiotics. aerobic and anaerobic cultures were taken of venous blood, from the peritoneal cavity at operation, and of any subsequent wound and/or intraperitoneal infection. no significant differences between fatal and nonfatal cases were noted with respect to presence of anaerobes in the peritoneal flora (six babies with two deaths) or culture-confirmed b ... | 1979 | 390716 |
| the pathology of human cardiac transplantation: an assessment after 11 years' experience at groote schuur hospital. | over a period of 11 years, commencing in december 1967, 31 cardiac transplants, 10 orthotopic and 21 heterotopic, were performed at groote schuur hospital. two patients with orthotopic transplants have a long survival, 1 for 7 1/2 and 1 for 9 1/2 years, and 1 with a heterotopic transplant for 4 years. eighteen patients have died, and autopsy was performed from 13 to 623 days postoperatively. rejection of the donor heart was found in 61,1% and was the cause of death in 44,4% of cases. infection, ... | 1979 | 390737 |
| indirect sandwich enzyme-linked immunosorbent assay for rapid detection of haemophilus influenzae type b infection. | we report the development and testing of an enzyme-linked immunosorbent assay with excellent sensitivity for the detection of haemophilus influenzae type b (hi(b)) antigen in clinical specimens from patients with hi(b) meningitis. the assay, an indirect sandwich technique, uses polystyrene balls as a solid phase and an alkaline phosphatase-labeled goat anti-rabbit globulin conjugate. specimens are incubated with polystyrene balls armed with burro anti-hi(b) antiserum, and recognition antibody is ... | 1979 | 393714 |
| semiquantitative catalase test as an aid in identification of oxidative and nonsaccharolytic gram-negative bacteria. | a simple and rapid semiquantitative slide catalase test useful for the identification of oxidative and nonsaccharolytic gram-negative bacteria, i.e., "nonfermenters," is described. using the interpretative criterion of time of appearance of oxygen bubbles in 3% hydrogen peroxide, three categories of nonfermenters were established. the rapid catalase producers included achromobacter xylosoxidans and achromobacter species; acinetobacter anitratus and acinetobacter lwoffii; bordetella bronchiseptic ... | 1979 | 393719 |
| [bacteriological in vitro investigations with cefaclor. correlation of inhibition zone diameter and minimal inhibitory concentration (author's transl)]. | a comparison of the minimal inhibitory concentrations (mic) of cefaclor and cephalexin shows that cefaclor is noticeably superior against citrobacter. enterobacter and proteus mirabilis. only slight differences are seen against other enterobacteria and staphylococcus aureus. both cefaclor and cephalexin are completely ineffective against enterococci and pseudomonas aeruginosa. regression analysis to correlate the inhibition zone diameter and mic of cefaclor produced a very good correlation (r = ... | 1979 | 399245 |
| in vitro antimicrobial activity of some cyclic hydroxamic acids and related lactams. | against enterobacter aerogenes 13048, serratia marcescens 13880, klebsiella pneumoniae 10031, pseudomonas aeruginosa 10145, escherichia coli 9723, lactobacillus casei 7469, lactobacillus plantarum 8014, leuconostoc dextranicum 8086, and streptococcus faecalis 8043, the mean minimal inhibitory concentrations of three cyclic hydroxamic acids, 3-amino-3,4-dihydro-1-hydroxycarbostyril, the 6-chloro analog, and the 7-chloro analog, were 0.6, 0.6, and 0.2 micrograms/ml, and those of the corresponding ... | 1978 | 400828 |
| absence of clinical pneumonia following bronchoscopy with contaminated and clean bronchofiberscopes. | two hundred forty-nine fiberoptic bronchoscopy procedures were surveyed for the presence of bronchoscopy-related pneumonia. the first 103 procedures were performed during a period when the fiberscope was presemably contaminated with pseudomonas aeruginosa. chart review of these 103 procedures and prospective epidemiologic surveillance of the remaining 146 procedures revealed no cases of bronchoscopy-related pneumonia. | 1977 | 401481 |
| plasmid-determined resistance to tellurium compounds. | transferable plasmids in gram-negative bacteria that confer resistance to potassium tellurite or tellurate were found. this re-istance was distinct from resistance to mercury, silver, or arsenic compounds and was unrelated to antibiotic resistance. in escherichia coli, plasmids determine a 100-fold increase in the minimal inhibitory concentration for tellurite and a 10-fold increase in tellurate resistance. many, but not all, of the plasmids belong to incompatibility group s. in pseudomonas aeru ... | 1977 | 401494 |
| appearance of straight flagellar filaments in the presence of p-fluorophenylalanine in pseudomonas aeruginosa. | in the presence of p-fluorophenylalanine, a normally flagellated strain of pseudomonas aeruginosa produced straight flagellar filaments at the distal ends of preexisting flagella, indicating polar growth on its flagella. | 1977 | 401502 |
| treatment of pulmonary infections in patients with cystic fibrosis: a comparative study of ticarcillin and gentamicin. | the effectiveness of ticarcillin against pseudomonas aeruginosa in acute exacerbations of pulmonary infection in patients with cystic fibrosis was evaluated. seventy-one percent of patients treated with ticarcillin alone responded favorably. the response rate was similar in patients treated with a combination of ticarcillin plus gentamicin or with gentamicin alone. severity of the underlying disease was the most important determinant of response to treatment. ticarcillin-resistant organisms were ... | 1977 | 401521 |
| r plasmids coding for gentamicin, tobramycin, and carbenicillin resistance in serratia, klebsiella and escherichia coli strains from a single clinical source. | serratia marcescens, klebsiella sp. and escherichia coli strains bearing transferable resistance to aminoglycoside antibiotics, namely, gentamicin, tobramycin, kanamycin, streptomycin, lividomycin, and carbenicillin, as well as to a series of more classical drugs, began to emerge in materials from the frankfurt university hospital. plasmids from serratia, klebsiella, and e. coli exhibit a broad host range in that they are transferable to e. coli, proteus mirabilis and salmonella typhimurium rece ... | 1977 | 401718 |
| the action of fosfomycin on the growth of pseudomonas aeruginosa. | a study was made of the effect of the inoculum size and the culture conditions on the mic of a strain of pseudomonas aeruginosa that was sensitive to fosfomycin. the increase of the inoculum and the conditions which favour the cellular multiplication considerably increase the mic. phosphates inhibit the action of the antibiotic. fosfomycin produces a logarithmic decrease in the number surviving 1 h after being added; the bacterial lysis measured by the decrease in the od depends on the medium an ... | 1977 | 401719 |
| in vivo distribution of pseudomonas aeruginosa slime glycolipoprotein: association with leukocytes. | intraperitoneal injection of slime glycolipoprotein (glp) from pseudomonas aeruginosa induced leukopenia and death of mice, similar to the effect of infection with viable organisms. differential counts established that the leukopenia was characterized by a decrease in the number of polymorphonuclear leukocytes, followed by death of mice. mice immunized with glp survived challenge and responded with a leukocytosis that had a substantial increase in circulating polymorphonuclear leukocytes. leukoc ... | 1977 | 401769 |
| pathogenesis of corneal damage from pseudomonas exotoxin a. | pseudomonas aeruginosa exotoxin a was injected into rabbit corneas. death of epithelial, endothelial, and stromal cells resulted, and necrosis of the cornea followed. control eyes with exotoxin neutralized by specific antitoxin showed minimal damage. a dose-response pattern was evident. antitoxin neutralization of pseudomonas exotoxin a in corneal ulcers may have possible therapeutic implications. | 1977 | 401777 |
| nitrogen 15 tracer studies on the pathway of denitrification in pseudomonas aeruginosa. | the pathway of anaerobic reduction of nitrite to nitrogen gas (n2) by cell suspensions of the denitrifier, pseudomonas aeruginosa, was studied using the techniques of gas chromatography and mass spectrometry. while release of nitrous oxide (n2o) is not normally detected during the reduction of nitrite to n2 by this organism, 15n from [15n]nitrite nevertheless can be trapped quantitatively as 15n2o in a pool of added n2o. in such experiments the abundance of 15n in n2o always exceeds that in prod ... | 1977 | 401809 |
| effect of n-acetylcysteine on antibiotic activity and bacterial growth in vitro. | the antibiotic bacerial inactivity of n-acetylcysteine (nac) and its interaction with penicillin and aminocyclitol antibiotics was evaluated. nac inhibited growth of both gram-negative and gram-positive bacteria. strains of pseudomonas aeruginosa were more susceptible than other microorgainsms tested. p. aeruginosa strains were inhibited synergistically by nac and carbenicillin or ticarcillin. however, nac antagonized the activity of gentamicin and tobramycin. these findings have implications fo ... | 1977 | 401831 |
| comparison of amikacin and tobramycin in the treatment of infection in patients with cancer. | two new aminoglycoside antibiotics, tobramycin and amikacin, were compared in a randomized study of the treatment of infections in patients with cancer. for the identified infections, the response rate for tobramycin was 60% and for amikacin was 64%. pneumonia, urinary tract infection, and septicemia were the most frequent infections. most (78%) of the identified pathogens were gram-negative bacilli; klebsiella pneumoniae, escherichia coli, and pseudomonas aeruginosa were the most frequently iso ... | 1977 | 401853 |
| extraction and purification of specific antibody against pseudomonas aeruginosa by immune affinity chromatography. | immune affinity chromatography has been used to extract and purify specific immune antibody against p. aeruginosa immunotype 4 from hyperimmune gamma glubulin containing antibody against each of seven major immunotypes of p. aeruginosa. a column with a 4 ml. bed volume was construced which had a "working capacity" of approximately 1,680 agglutination units. with water used as the eluting agent, 100 percent yields of functionally active antibody were obtained when amounts equal to or less than th ... | 1977 | 401855 |
| persistence of a specific pseudomonas infection in a large general hospital. | of at least 37 strains of pseudomonas aeruginosa distinguishable by their pyocine production, type 10 is noteworthy for its relative rarity and its virulence to man. opportunistic infections by this organism occurring in a single hospital over 8 years are described, and its ecology discussed with reference to its possible control. | 1977 | 402023 |
| effect of prolonged bacteremia on leukocyte bactericidal function. | neutrophil bactericidal function (nbf) was studied in dogs during intravenous infusions of pseudomonas aeruginosa. administration of 10(6) bacteria per minute over 3 hours was associated with a bacteremia level of about 10(3) organisms per milliliter of blood without adverse effects on nbf. infusion of 10(7) organisms per minute resulted in blood bacterial counts in the upper 10(4) range and significantly impaired nbf. to determine the relative contribution of the spleen in bacterial phagocytosi ... | 1977 | 402038 |
| isolation of drug-resistant bacteria from newborn infants. | the fetus is known to be bacteria-free and is contaminated with bacteria during birth. we examined drug-resistant bacteria in feces of new-born infants to know the distribution of drug-resistant bacteria in a hospital. among 76 infants examined, we could isolate drug-resistant strains of bacteria from 65 infants (86%). we collected 110 drug-resistant strains of escherichia coli, klebisella pneumoniae, and pseudomonas aeruginosa, and could isolate 53 strains (48%) carrying r plasmids; they being ... | 1977 | 402039 |
| in vitro activity of netilmicin, gentamicin, and amikacin. | the in vitro activity of netilmicin (sch 20569), a new semisynthetic derivative of gentamicin, was compared with that of gentamicin and amikacin. one hundred and ninety-two clinical isolates of enterobacteriaceae, pseudomonas aeruginosa, and staphylococcus aureus were tested using both agar and broth dilution techniques. netilmicin was comparable to gentamicin, with the following exceptions: (i) for serratia marcescens and p. aeruginosa, gentamicin was more active than netilmicin; (ii) all strai ... | 1977 | 402104 |
| heterologous transfection with bacteriophage phix174 dna. unusual heterogeneous products. | hydroxylamine-resistant infectious materials (harim) synthesized in natural non-host and progeny phage low productive bacterial spheroplasts upon transfection with bacteriophage phix174 dna were found to be unusually heterogeneous in their forms. using pseudomonas aeruginosa as a source of harim, it was shown that they have the following unusual features. (1) almost all of the harim are denser than normal single-stranded (ss)- and double-stranded replicative form (rf)-dnas of phix174 found usual ... | 1977 | 402155 |
| serum effects on the response of mammalian cells to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae. | the response of mammalian cells to pseudomonas and diphtheria exotoxins was studied. a method was developed whereby the sensitivity of cells to these two toxins could be quantitated. the method is versatile and can be used to study the effects of toxins on many cellular metabolic or transport processes. the type of serum used in the culture medium significantly influenced the response of cells to the toxins. calf, horse, and human sera protected cells while fetal calf serum did not. precipitatio ... | 1977 | 402176 |
| a new polyvalent pseudomonas vaccine. | this paper describes the preparation, chemical characterisation and immunogenic properties of a new polyvalent pseudomonas vaccine. new cultural methods were devised which allowed a build-up of the immunogen in the cell wall of the bacteria, and mild extraction techniques were used to remove the immunogens from the cell wall of living bacteria without apparent physical or chemical change which might affect immunogenicity. the polyvalent vaccine comprised 16 component vaccines, each a lipid-prote ... | 1977 | 402473 |
| pseudomonas mastoiditis. | opportunistic infections of the external auditory canal or the middle ear due to pseudomonas aeruginosa occurring in patients with low resistance to infection have a 35 percent mortality rate. once the process extends into the pneumatized temporal bone, eradication becomes more difficult and the mortality rate increases to 72 percent because of the high incidence of involvement of cranial nerves, adjacent intracranial vessels, and meningitis. treatment is directed towards the underlying conditio ... | 1977 | 402522 |
| [antibiotic sensitivity of proteus, pseudomonas pyocyanea and staphyloccoci isolated from scleroma and ozena patients]. | antibiotic sensitivity of 292 strains of proteus, 60 strains of ps, aeruginosa, 309 strains of s. aureus and 88 strains of s. epidermidis isolated from the upper respiratory tract of patients with scleroma and ozena was studied. the cultures of pr. mirabilis were sensitive to aminoglucosides (54.9-96.2 per cent) and pr. morganii were sensitive to levomycetin (81.5 per cent) and neomycin (92.6 per cnet). sensitivity of pr. vulgaris and pr. morganii was reliably higher (p less than 0.001) than tha ... | 1977 | 402886 |
| aeruginocine typing and antibiotic sensitivity of pseudomonas aeruginosa of poultry origin. | aeruginocine typing and an antibiotic sensitivity test were conducted on 277 strains of pseudomonas aeruginosa isolated from dead-in-shell embryos and on water from waterers of a chick hatchery. thirty different aeruginocine patterns were obtained using 8 wahba indicator strains. of the 277 strains, 129 were typable and 148 were not. the aeruginocine typing patterns of the strains isolated from dead-in-shell embryos and water were similar, suggesting that contaminated water may be the source of ... | 1977 | 402907 |
| separation of the cytoplasmic and outer membrane of pseudomonas aeruginosa paq. | | 1977 | 402912 |
| pyocin sensitivity of neisseria gonorrhoeae and its feasibility as an epidemiological tool. | pyocin inhibition of neisseria gonorrhoeae and its feasibility as a gonococcal typing scheme were examined. mitomycin c-induced pyocin lysates of pseudomonas aeruginosa were able to selectively inhibit the growth of gonococcal strains. the particles associated with the inhibitory activity were non-dialyzable, heat labile, pronase sensitive, trypsin resistant, and of large molecular weight by membrane and gel filtration techniques. the inhibitory activity was shown to be specific by absorption wi ... | 1977 | 403141 |
| characterization of a translocation unit encoding resistance to mercuric ions that occurs on a nonconjugative plasmid in pseudomonas aeruginosa. | the nonconjugative plasmid, pvs1, has a molecular weight of 18.5 x 10(6) and confers resistance to sulfonamides and to mercuric ions. in pseudomonas aeruginosa pao, the transfer can be mobilized by a variety of conjugative plasmids, and the process does not require a functional recombination system in the donor. hybrid plasmids that arise by the relocation of the mer gene onto the mobilizing plasmid can be isolated readily, and, as far as can be determined, these hybrids retain the genome of the ... | 1977 | 403173 |
| properties of derivatives of the pseudomonas plasmid pvs1 that have inherited carbenicillin resistance from rp1. | a procedure is described for the isolation, in pseudomonas aeruginosa pao, of bacteria carrying derivatives of pvs1 that inherited the carbenicillin-resistance determinant from rp1 either alone or together with that for aeruginocin resistance. such bacteria occur among the transconjugant progeny from both recombination-proficient or -deficient pvs1+ rp1+ donors, suggesting that the formation of these plasmids is due to the translocation of tna from rp1 into pvs1. it is possible, therefore, that ... | 1977 | 403183 |
| a fluorescent probe response to the interaction of pyocin r1 with sensitive cells. | additon of pyocin r1, a bacteriocin of pseudomonas aeruginosa, to sensitive cells caused a fluorescence increase of 8-anilino-1-naphthalenesulfonate (ans) in the cell suspension. the reaction was rapid, starting with a short time lag after adsorption of pyocin onto the cells and finishing within several minutes. the fluorescence response was attributed to the interaction of the cell body and ans, not to that of the medium outside the cells and ans. the maximal amplitude of fluorescence after pyo ... | 1977 | 403184 |
| evaluation of a simple device for bacteriological sampling of respirator-generated aerosols. | the aerotest sampler (olympic medical corp., seattle, wash.) is designed to detect bacterial contamination of respirator-generated aerosols in a simple one-step process. the sampler was evaluated by controlled contamination of bennett ap-5, pr-2, and ma-1 respirators with escherichia coli, pseudomonas aeruginosa, and acinetobacter. bacteria present as viable 1.4 to 3.5-mum particles in each of 77 aerosols were quantitated by using the andersen viable-particle sampler, and the results were compar ... | 1977 | 403199 |
| experimental pneumonia due to pseudomonas aeruginosa in leukopenic dogs: prolongation of survival by combined treatment with passive antibody to pseudomonas and granulocyte transfusions. | treatment with type-specific igg antibody to pseudomonas aeruginosa significantly increased rates of survival after experimental induction of pseudomonas pneumonia in leukopenic dogs. longer survival times were correlated with higher titers of circulating antibody in serum; however, no animals treated with antibody alone were long-term survivors. subsequent development of sepsis or the recovery of pseudomonas from infected lung tissue was not altered by treatment with antibody. therapy with gran ... | 1977 | 403242 |
| treatment of mixed bacterial infections with clindamycin and gentamicin. | thirty-eight patients with severe mixed bacterial infections were treated with clindamycin and gentamicin. in vitro, all staphylococci and streptococci (other than enterococci) and 96% of anaerobes were susceptible to clindamycin; all staphylococci and 92% of enterobacteriaceae and pseudomonas aeruginosa were susceptible to gentamicin. enterococci were usually resistant to both antibiotics. significant synergy was only occasionally observed with this combination of antibiotics; there were no ins ... | 1977 | 403243 |
| [pulmonary artery obstruction associated with pseudomonas aeruginosa pneumonia - with special reference to its etiology and surgical treatment]. | | 1977 | 403366 |
| gamma heavy chain disease--presenting as pancytopenia and splenomegaly. | a patient with gamma heavy chain disease (franklin's disease) was discovered during evaluation for pancytopenia and splenomegaly. lymphadenopathy, palatal edema, and infiltration of the bone marrow palatal edema, and infiltration of the bone marrow with abnormal cells were all absent. serum and urine protein electrophoresis demonstrated a monoclonal protein migrating in the beta region. immunoelectrophoresis showed that it reacted with antibodies against the fc fragment of igg heavy chains (gamm ... | 1977 | 403613 |
| [tobramycin: comparison with gentamicin and carbenicillin in regard to 200 serotyped strains of pseudomonas aeruginosa]. | | 1977 | 403645 |
| typing of pseudomonas aeruginosa by production of pyocines. | | 1977 | 403683 |
| immunosuppressive effect of pseudomonas aeruginosa endotoxin on lymphocyte transformation in vitro. | in order to prove the immunosuppressive activity of an endotoxic fraction from pathogenic ps. aeruginosa, the lymphoblastic transformation test was used. the results have shown that lymphocytes cultured in presence of pha and endotoxin have a decreased rate of dna synthesis and oxygen uptake. on the contrary, there seemed to be a slight relative increase of rna and protein synthesis as compared with pha-transformed cells. | 1977 | 403710 |
| [studies on serological classification of pseudomonas aeruginosa using the indirect fluorescent antibody technique (author's transl)]. | an application mode of the indirect fluorescent antibody technique is described which allows the differentiation of soma and flagella of ps. aeruginosa cells on the morphological and serological level simultaneously and the determination of the topic specificity of ps. aeruginosa antisera. antisera prepared by immunization of rabbits with formalinized semisolid agar cultures react with somatic and flagellar antigens (anti-oh-sera), while antisera made with heated cultures strain somatic antigens ... | 1977 | 403711 |
| effects of the common protective antigen (oep) and toxoids of protease and elastase from pseudomonas aeruginosa on protection against hemorrhagic pneumonia in mink. | the effects of common protective antigen (oep) of pseudomonas aeruginosa strain n10 (serotype 5) and oep plus toxoids of protease and elastase from p. aeruginosa strains ifo 3080 and ifo 3455 were studied during an enzootic of hemorrhagic pneumonia caused by p. aeruginosa serotype 3 in mink. the overall mortality rate in non-vaccinated mink was 24.8% (524 mink). it was highest in male kittens, followed by female kittens and adults. oep (1,000 millimicrong) plus toxoids (each 1,000 millimicrong o ... | 1977 | 403712 |
| comparative clinical pharmacology of amikacin and kanamycin in dairy calves. | the in vitro susceptibility of escherichia coli, salmonella sp, pasteurella multocida, and pseudomonas aeruginosa strains isolated from young calves and their environment to kanamycin and its semisynthetic derivative--amikacin, was compared by the tube dilution method. the minimal inhibitory concentration of amikacin was two- to fourfold lower than the minimal inhibitory concentration of kanamycin for the salmonella group b, ps aeruginosa and p multocida strains examined, whereas the e coli and ... | 1977 | 403834 |
| transfer of a plasmid-specified beta-lactamase gene from haemophilus influenzae. | a number of ampicillin-resistant strains of haemophilus influenzae could donate a gene specifying the type iiia (tem) beta-lactamase to haemophilus parainfluenzae, escherichia coli, and pseudomonas aeruginosa. donor strains rapidly lost their ability to transfer ampicillin resistance on storage or subculture. such strains also apparently contained a single species of covalently closed circular deoxyribonucleic acid of contour length 1.2 mum, equivalent to about 2.5 x 10(6) daltons. no species of ... | 1977 | 403856 |
| confirmation of the single-step membrane filtration procedure for estimating pseudomonas aeruginosa densities in water. | the efficiency of two procedures, membrane filtration and most probable number, to resuscitate and enumerate pseudomonas aeruginosa have been compared at two temperatures and varying incubation periods. data indicate that the membrane filtration procedure using mpa or mpa medium b is more efficient than the most-probable-number procedure in estimating p. aeruginosa populations. it was also found that the specificity of the membrane filtration procedure was such that 92 to 99% of the colonies cou ... | 1977 | 403858 |
| amino components of the lipopolysaccharide from pseudomonas aeruginosa n.c.t.c. 8505. presence of 2,4-diamino-2,4,6-trideoxy-d-glucose. | configurations were determined for previously identified amino components of the lipopolysaccharide from pseudomonas aeruginosa n.c.t.c. 8505. glucosamine and galactosamine belong to the d-series, and alanine and aminogalacturonic acid to the l-series. an additional amino component was identified as 2,4-diamino-2,4,6-trideoxy-d-glucose. this compound may be a characteristic component of the o-specific chain in lipopolysaccharides of strains of pseudomonas aeruginosa belonging to habs sero-group ... | 1977 | 403906 |
| [bacterial endocarditis. clinical picture, treatment and course in 37 patients (author's transl)]. | between march 1971 and april 1976 37 patients were seen with manifest bacterial endocarditis. the main signs were high temperature and cardiac murmurs whereas other "classical" signs such as splenomegaly, anaemia, leucocytosis, and positive anti-streptolysin titres were much less frequent. in 35 cases bacteriological proof was possible. as causative organism a total of 30 gram-positive organisms (of which 15 were streptococcus viridans and 8 were staphylococcus species) and 10 gram-negative bact ... | 1977 | 404127 |
| relationship between habs serotypes and 2-amino sugar composition of pseudomonas aeruginosa. | thirteen habs-serotype strains could be classified into 11 groups depending on the characteristic patterns of 2-amino sugar composition; strains of serotypes 2, 5, and 7 had the same pattern, and each other serotype strain had its own distinctive pattern. in our classification, fucosamine and quinovosamine were of importance. we found that fucosamine from strain p14 (habs serotype 1) was of the d configuration only, unlike dl-fucosamine from strain n10 (habs serotype 11). | 1977 | 404240 |
| exotoxin production by clinical isolates of pseudomonas aeruginosa. | seventy-five consecutive clinical pseudomonas aeruginosa isolates were tested for in vitro exotoxin production. exotoxin was demonstrated in culture filtrates biologically, by its ability to produce characteristic dermonecrotic lesions in guinea pigs, and seriologically, by counterimmunoelectrophoresis (cie) with rabbit antiserum elicited with purified exotoxin. by these two methods, exotoxin was detected in 87 and 89% of p. aeruginosa strains, respectively (r = 0.48, p less than 0.001). althoug ... | 1977 | 404244 |
| sensitivity of gram-negative bacteria to six aminoglycoside antibiotics. | an in vitro study of the susceptibility of 201 newly isolated strains of gramnegative bacteria to six aminoglycoside antibiotics (kanamycin, amikacin, gentamicin, tobramycin, sisomicin and netilmicin) was performed by the twofold dilution method in fluid medium. both the minimal inhibitory concentration and the minimal bacteridical concentration were determined. overall, tobramycin seemed the most effective of the drugs studied. netilmicin, the new derivative from sisomicin, compared favourably ... | 1977 | 404254 |
| hydrolysis of lithocholate sulfate by pseudomonas aeruginosa. | pseudomonas aeruginosa was found to be able to hydrolyze bile sulfate. this property was observed when lithocholate sulfate was substituted for the sulfur source in the culture medium. the addition of mgso4 to the medium inhibited the hydrolysis of the bile sulfate. | 1977 | 404286 |
| the isolation and characterization of lipopolysaccharide-defective mutants of pseudomonas aeruginosa pac1. | mutants with defective lipopolysaccharides (lpss) were isolated from pseudomonas aeruginosa pacir (habs serogroup 3) by selection for resistance to aeruginocin from p. aeruginosa pi6 carbenicillin-sensitive mutants were isolated from p. aeruginosa paci but not all had defective lpss. rough colonial morphology and resistance to bacteriophage ii9x appeared to be independent of lps composition. the lpss from five mutants were analysed and compared with that of the parent strain. separation of parti ... | 1977 | 404391 |
| [laboratory studies on antibiotic chemotherapy of pseudomonas aeruginosa infections (author's transl)]. | majority of pseudomonas aeruginosa strains were inhibited at 25 approximately 50 microng/ml of carbenicillin. there was no difference in mic's determined using either mueller-hinton agar or heart infusion agar. all strains which showed one plus or more sensitivity in either of mono- or tri-disc test showed mic of 100 microng/ml or less. in view of the high serum concentrations obtainable with 20 approximately 30 g per day dose of carbenicillin, the disc sensitivity test for this antibiotic shoul ... | 1977 | 404446 |
| serotyping of pseudomonas aeruginosa isolated from clinical specimens. | serotyping of 168 clinical isolates by the slide agglutination test using tibs (toshiba institute of biological science) serotyping sera, which were prepared from homma's serotype strains at the request of pseudomonas aeruginosa serotype committee in japan, was performed and the results were compared with serotyping using imsut (institute of medical science, university of tokyo) serotyping sera by the tube agglutination test. when heat-killed antigen from clinical isolates were used, both sets o ... | 1977 | 404450 |
| the enhancement of phagocytosis and intra-cellular killing of pseudomonas aeruginosa and its common antigen (oep) coated latex particles by mouse spleen macrophages to which anti-oep-igg and gentamicin have been added. | this experiment was performed using macrophages derived from mouse spleens immunized or non-immunized with the common antigen (oep) of pseudomonas aeruginosa. the phagocytosis of these macrophages of live or formalin killed pseudomonas aeruginosa and latex particles coated with oep were enhanced by the addition of anti-oep-igg, but not by immunoglobulin taken from normal mice. the macrophages from mice immunized with oep showed significantly enhanced phagocytosis of latex particles coated with o ... | 1977 | 404451 |
| [toxin production by pseudomonas aeruginosa strains isolated from children and their environment]. | | 1977 | 404481 |
| [role of cosubstrates in the microbiologic oxidation of xylene isomers by a culture of pseudomonas aeruginosa]. | cosubstrates (additional substrates) produced different effect on transformation of isomeric xylenes of pseudomonas aeruginosa 7. the cosubstrates manifested the highest stimulating effect on transformation of o-xylene, on which the culture did not grow, and p-xylene, in the presence of which only a weak growth was detected. the most effective cosubstrates were xylose and maltose which were actively oxidized by the culture but could not serve as carbon sources. one of mechanisms of the cosubstra ... | 1977 | 404511 |
| pseudomonas aeruginosa infection in cystic fibrosis. diagnostic and prognostic significance of pseudomonas aeruginosa precipitins determined by means of crossed immunoelectrophoresis. | a total of 133 patients with cystic fibrosis have been followed for up to 5 years with monthly examinations including bacteriological examinations of sputum. sera from the patients were examined by means of crossed immunoelectrophoresis for the occurence and number of precipitating antibody specificites against pseudomonas aeruginosa. poor prognosis in cystic fibrosis was associated with chronic colonization (9 months - more than 5 years) of the respiratory tract with mucoid pseudomonas aerugino ... | 1977 | 404701 |
| pseudomonas aeruginosa infection in cystic fibrosis. bactericidal effect of serum from normal individuals and patients with cystic fibrosis on p. aeruginosa strains from patients with cystic fibrosis or other diseases. | p. aeruginosa strains originating from the respiratory tract of patients with cystic fibrosis (cf) and patients with other diseases (non-cf) were analysed with regard to their sensitivity to the bactericidal activity of human serum. p. aeruginosa strains isolated from cf patients were more sensitive than strains from non-cf patients to the bactericidal activity of normal human serum. the bactericidal activity was heatlabile. as regards the sensitivity to normal human serum, mucoid and non-mucoid ... | 1977 | 404841 |
| antibodies against pseudomonas aeruginosa in serum from normal persons and patients colonized with mucoid or non-mucoid pseudomonas aeruginosa: results obtained by crossed immunoelectrophoresis. | serum from 154 normal persons was investigated for precipitating antibodies against p. aeruginosa by crossed immunoelectrophoresis, using a polyvalent p. aeruginosa standard antigen. ninety-four per cent of the sera contained no demonstrable precipitins, and 6% contained precipitins against only one p. aeruginosa antigen. thirty-four per cent of sera from 122 patients colonized with p. aeruginosa in various anatomical regions contained precipitins against 2 to 41 p. aeruginosa antigens. serum fr ... | 1977 | 404843 |
| pseudomonas aeruginosa bacteremia in a dialysis unit. 1. recognition of cases, epidemiologic studies and attempts at control. | infections commonly occur in patients undergoing dialysis and have been related to diminished host resistance of uremic patients, the arteriovenous fistulas and bacteriologic contamination of dialysis fluids. the occurrence of four cases of bacteremia due to pseudomonas, three of which were type 7, and the presence of this serotype in the dialysis fluids suggested an important association between infection and growth of bacteria in the fluids. attempts to reduce levels of bacteria in the dialysi ... | 1977 | 404878 |
| pseudomonas aeruginosa bacteremia in a dialysis unit. 11. relationship to reuse of coils. | blood for culture was obtained over a six week period from 17 patients undergoing long-term hemodialysis. bacteremia was detected during 18 of 201 dialyses. blood drawn during fifteen of these dialyses contained pseudomonas aeruginosa. ten of the 17 patients (59 per cent) had a pseudomonas bacteremia some time during the study. only one patient was symptomatic. the frequency of positive cultures was related to reuse of coils. no cultures were positive until after the fifth use, but by the tenth ... | 1977 | 404879 |
| chemically defined antimicrobial susceptibility test medium for pseudomonas aeruginosa. | a chemically defined growth medium containing physiological concentrations of magnesium and calcium ions was utilized in a microdilution procedure for antimicrobial drug susceptibility testing of pseudomonas aeruginosa. determinations of growth end points were simplified by use of sodium citrate as a sole carbon source and bromothymol blue as a ph indicator. growth of the test organisms was detectable by a change in the indicator color from green to blue after alkalinization of the medium due to ... | 1977 | 404961 |
| pirbenicillin: comparison with carbenicillin and bl-p1654, alone and with gentamicin, against pseudomonas aeruginosa. | minimum inhibitory concentrations (mic) of pirbenicillin against 135 clinical isolates of pseudomonas aeruginosa were one-fourth of those required for carbenicillin but two times higher than those for bl-p1654. increasing the inoculum size produced an adverse effect on the bactericidal activity for all three antibiotics. this was more apparent for pirbenicillin than for carbenicillin, but less than the effect on bl-p1654. when concentrations of antibiotics likely to be achieved clinically were u ... | 1977 | 404963 |
| pseudomonas aeruginosa strain isolated in france that carries a plasmid determining carbenicillin resistance. | a plasmid, r56be, derived from a clinical strain of pseudomonas aeruginosa isolated in france in 1973 has been studied. this plasmid confers resistance only to carbenicillin, and although freely transferable between unrelated strains of p. aeruginosa, its transfer from p. aeruginosa to escherichia coli k-12 was undetectable. r56be could not be isolated as covalently closed circular deoxyribonucleic acid, but the plasmid could be transduced intact by phage f116l. this suggests that its molecular ... | 1977 | 404966 |
| analytical characterization of lipopolysaccharide antigens from seven strains of pseudomonas aeruginosa. | lipopolysaccharide antigens from seven different serotype strains (antigen immunotypes nos. 1-7 in the classification of fisher et al.3) of pseudomonas aeruginosa have been analyzed for neutral carbohydrate, amino sugars, lipid, protein, 3-deoxy-manno-octulosonic acid, and phosphorus. the individual amino sugars were determined for each antigen type; all contained 2-amino-2-deoxy-d-glucose and -d-galactose, together with 2-amino-2,6-dideoxygalactose; the latter as isolated from the type 2 antige ... | 1977 | 405103 |
| bactericidal activity of amikacin and gentamicin. | using the membrane filtration method bactericidal activity of amikacin and gentamicin as a function of time and concentrations was determined. amikacin was bactericidal against all pseudomonas aeruginosa (n = 7) and klebsiella pneumoniae strains (n = 8) tested. in 5 of the 7 p. aeruginosa and 3 of the 8 k. pneumoniae strains we saw a secondary regrowth at 24h. there was no difference between amikacin and gentamicin. the experiments to determine the effect of concentration on bactericidal activit ... | 1977 | 405182 |
| bacteriological studies in a patient with antibiotic-associated pseudomembranous colitis. | detailed aerobic and anaerobic bacteriological studies on the operative specimen from a patient with antibiotic-associated pseudomembranous colitis revealed approximately 10(11) facultatively anaerobic bacteria, but less than 10(5) obligate anaerobes per g of involved colonic tissue. fourteen isolates of escherichia coli, three isolates of pseudomonas aeruginosa, and two isolates of streptococcus fecalis were identified. the majority of the organisms were resistant to most of the antibiotics tha ... | 1977 | 405269 |
| pseudomonas protease. purification, partial characterization, and its effect on collagen, proteoglycan, and rabbit corneas. | the extracellular protease of a virulent strain of pseudomonas aeruginosa was purified by deae-cellulose chromatography in two steps. sds-polyacrylamide gel electrophoresis of the purified enzyme revealed a single band, and the enzyme was shown to be the major component of the bacterial filtrate. the protease was fully inhibited by na2 edta, 1,10-orthophenanthroline, l-cysteine and zn+2 ions but was insensitive to dissopropylphosphofluoridate. the elastase substrates orcein-elastin and acetyl-l- ... | 1977 | 405343 |
| sp127, a bacterial protein enhancing the activity of macrolide antibiotics against pseudomonas aeruginosa: isolation and characterization. | some strains belonging to the genera bacillus and pseudomonas were found to produce in the culture broth, a protein which synergistically enhanced the activity of macrolide antibiotics against pseudomonas aeroginosa. the protein produced by bacillus brevis atcc 8185, designated sp127, was isolated in a pure state by means of ammonium sulfate fractionation, cm-cellulose column chromatography and gel filtration on sephadex g-100. the sedimentation coefficient and the molecular weight of sp127 were ... | 1977 | 405355 |
| mode of action of the protein, sp127, which enhances the activity of macrolide antibiotics against pseudomonas aeruginosa. | antibiotics, the activity of which enhanced against pseudomonas aeruginosa by sp127, were restricted to the basic macrolide antibiotics such as erythromycin, maridomycin and oleandomycin, the neutral macrolide antibiotics such as lankamycin and lankacidin c, vancomycin and enramycin. synergistic activity of sp127 with the above antibiotics was found against pseudomonas aeruginosa and several strains of escherichia coli, but not against proteus vulgaris and macrolide-resistant staphylococcus aure ... | 1977 | 405356 |
| acute otitis externa in divers working in the north sea: a microbiological survey of seven saturation dives. | saturation diving is an important and widely used technique in the offshore oil industry. during 1974-5 two saturation dives in the north sea were terminated because of outbreaks of incapacitating otitis externa, and others were disrupted. pseudomonas aeruginosa was consistently isolated from the ears of affected divers. because complex work schedules were threatened seven subsequent dives were subjected to microbiological monitoring and control. colonization of ear canal with p. aeruginosa or w ... | 1977 | 405421 |
| [development in the study of pseudomonas aeruginosa]. | | 1977 | 405439 |
| catabolism of l-lysine by pseudomonas aeruginosa. | pseudomonas aeruginosa paci grows poorly on l-lysine as sole source of carbon but mutant derivatives which grow rapidly were readily isolated. studies with one such mutant, p. aeruginosa pac586, supported the existence of a route for l-lysine catabolism which differes from those reported previously in other species of pseudomonas. the postulated route, the cadaverine or decarboxylase pathway, is initiated by the decarboxylation of l-lysine and involves the following steps: l-lysine leads to cadv ... | 1977 | 405455 |
| [gram-negative bacilli in otorhinolaryngologic infections--hemophilus influenzae and pseudomonas aeruginosa]. | | 1977 | 405515 |
| wide ranging plasmid bearing the pseudomonas aeruginosa tryptophan synthase genes. | | 1977 | 405620 |