| ontario's internationally educated nurses and waste in human capital. | to analyse critically the waste in human capital of ontario's internationally educated nurses resulting from unemployment or underemployment. | 2009 | 19646167 |
| adaptation of colonic fermentation and glucagon-like peptide-1 secretion with increased wheat fibre intake for 1 year in hyperinsulinaemic human subjects. | high cereal fibre intake is associated with reduced risk for type 2 diabetes, but wheat fibre had little or no effect on glycaemic control or oral glucose tolerance in clinical trials lasting 4-12 weeks. to explain this discrepancy, we hypothesised that colonic adaptation to increased wheat fibre intake takes many months but eventually results in increased scfa production and glucagon-like peptide-1 (glp-1) secretion. thus, the primary objective was to determine the time-course of the effects of ... | 2010 | 19664300 |
| prepublication data sharing. | rapid release of prepublication data has served the field of genomics well. attendees at a workshop in toronto recommend extending the practice to other biological data sets. | 2009 | 19741685 |
| flu pandemic prompts other vaccination delays. | | 2009 | 19770247 |
| improved flu screening needed at airports. | | 2009 | 19770256 |
| home chemotherapy for children with cancer: perspectives from health care professionals. | the goal of this study was to determine the perspectives of healthcare professionals (hps) from community and hospital settings involved in a paediatric home chemotherapy programme. using a prospective descriptive study design, hps including paediatricians, community nurses, hospital clinic nurses, administrators and pharmacists were interviewed using a moderately structured open-ended approach. through inductive content analysis, data were categorised under three themes reflecting hps' perspect ... | 2004 | 19777723 |
| task exposures in an office environment: a comparison of methods. | task-related factors such as frequency and duration are associated with musculoskeletal disorders in office settings. the primary objective was to compare various task recording methods as measures of exposure in an office workplace. a total of 41 workers from different jobs were recruited from a large urban newspaper (71% female, mean age 41 years sd 9.6). questionnaire, task diaries, direct observation and video methods were used to record tasks. a common set of task codes was used across meth ... | 2009 | 19787504 |
| the utility of podcasts in web 2.0 human anatomy. | | 2009 | 19799721 |
| pandemic flu: lessons from the toronto sars outbreak. | a review of the severe acute respiratory syndrome outbreak in ontario in 2003 found that there had been several faults in healthcare services and that these had contributed to the spread of infection and the deaths of two nurses. this article argues that, six years on, these faults have not been rectified and that ontario healthcare services may be unprepared for an h1n1 outbreak. the assistant deputy public health minister of toronto offers her response. | 2009 | 19807013 |
| expression of a common lqt1 mutation in five apparently unrelated families in a regional inherited arrhythmia clinic. | the inherited arrhythmia clinic at the university of western ontario services a catchment area of 1.5 million people and follows families with inherited arrhythmia syndromes. | 2010 | 19817925 |
| association with replication between estrogen-related receptor gamma (esrrgamma) polymorphisms and bone phenotypes in women of european ancestry. | osteoporosis is a bone disease characterized by low bone mineral density (bmd), a highly heritable polygenic trait. women are more prone than men to develop osteoporosis owing to a lower peak bone mass and accelerated bone loss at menopause. lack of estrogen thus is a major risk factor for osteoporosis. in addition to having strong similarity to the estrogen receptor 1 (esr1), the orphan nuclear estrogen-related receptor gamma (esrrgamma) is widely expressed and shows overlap with esr1 expressio ... | 2010 | 19821770 |
| modelling mitigation strategies for pandemic (h1n1) 2009. | the 2009 influenza a (h1n1) pandemic has required decision-makers to act in the face of substantial uncertainties. simulation models can be used to project the effectiveness of mitigation strategies, but the choice of the best scenario may change depending on model assumptions and uncertainties. | 2009 | 19825923 |
| a retrospective cohort pilot study to evaluate a triage tool for use in a pandemic. | the objective of this pilot study was to assess the usability of the draft ontario triage protocol, to estimate its potential impact on patient outcomes, and ability to increase resource availability based on a retrospective cohort of critically ill patients cared for during a non-pandemic period. | 2009 | 19874595 |
| the transcription factor gata-2 does not associate with angiographic coronary artery disease in the ottawa heart genomics and cleveland clinic genebank studies. | the transcription factor gata2 was reported to associate with coronary artery disease (cad) in the family-based genecard sample (connelly et al. in plos genet 2:e139, 2006). we asked whether gata2 associates with sporadic cases of cad in the ottawa heart genomics study (ohgs) and cleveland clinic (cc) populations. we genotyped the lead single nucleotide polymorphism (snp) from genecard, rs2713604 which is located in intron 5-6 of gata2 in 600 cad cases and 625 controls, as well as a tag snp rs15 ... | 2010 | 19885677 |
| knowledge of zoonoses among those affiliated with the ontario swine industry: a questionnaire administered to selected producers, allied personnel, and veterinarians. | zoonoses are diseases caused by infectious agents that are transmitted from animals to humans. some zoonoses have been associated with the pig and pork industry. to ensure the safety of pigs and pork and to improve public health it is essential to understand the level of knowledge of those affiliated with the swine industry. the purpose of our study was to assess the knowledge of and attitude toward zoonotic and other microbial hazards among targeted groups of stakeholders associated with the on ... | 2010 | 19895261 |
| human papillomavirus testing with pap triage for cervical cancer prevention in canada: a cost-effectiveness analysis. | recently published results from a large randomized trial (canadian cervical cancer screening trial study group) suggest that human papillomavirus testing followed by pap smear-based triage for human papillomavirus positive women may be an effective way to screen women for cervical cancer. we determined the potential cost-effectiveness of including human papillomavirus tests for cervical cancer screening for canada and three provinces: alberta, newfoundland and ontario. | 2009 | 19900264 |
| george's journey: developing a career path with supported employment. | this case study presents the career path of a young canadian man, george, as he recovered from significant mental illness and became a support worker in the mental health field. | 2009 | 19923662 |
| evaluation of forearm support provided by the workplace board on perceived tension, comfort and productivity in pregnant and non-pregnant computer users. | the aim of the study was to evaluate the effect of forearm support provided by the workplace board on perceived tension, comfort and productivity among pregnant and non-pregnant female computer workers. ten pregnant and 18 non-pregnant women participated in the study. participants completed three sets of tension/discomfort questionnaires at two week intervals. the first set was completed prior to any workstation intervention; the second set was completed after two weeks working with an ergonomic ... | 2009 | 19923677 |
| risk factors and outcomes among children admitted to hospital with pandemic h1n1 influenza. | limited data are available on disease characteristics and outcomes of children with 2009 pandemic influenza a(h1n1) virus infection (pandemic h1n1 influenza) who have required hospital admission. | 2010 | 19926677 |
| epidemiological summary of pandemic influenza a (h1n1) 2009 virus - ontario, canada, june 2009. | | 2009 | 19928301 |
| coagulase positive staphylococcal colonization of humans and their household pets. | staphylococcus aureus colonization was identified in 67/242 (28%) humans, 19/132 (14%) dogs, and 7/161 (4.3%) cats in households in ontario, with methicillin-resistant s. aureus present in 8 (3.3%) humans, 2 (1.5%) dogs, and 0 cats. staphylococcus pseudintermedius was isolated from 8 (4.1%) humans, 61 (46%) dogs, and 11 (6.8%) cats, with methicillin-resistant s. pseudintermedius detected in 1 (0.4%) human, 6 (4.5%) dogs, and 2 (1.2%) cats. staphylococcus schleiferi subspecies coagulans was isola ... | 2009 | 19949556 |
| influenza morbidity and mortality in elderly patients receiving statins: a cohort study. | statins possess immunomodulatory properties and have been proposed for reducing morbidity during an influenza pandemic. we sought to evaluate the effect of statins on hospitalizations and deaths related to seasonal influenza outbreaks. | 2009 | 19956645 |
| transformation to room service food delivery in a pediatric health care facility. | patient food service is an important component in the nutritional management of hospitalized children. the previous meal delivery system at the hospital for sick children in toronto was a cold-plating re-thermalized system. issues related to this model included order lead time, the reheating process, menu selection, and service style. research into other systems led us toward room service, an innovative and flexible mode of meal delivery. transformation to room service occurred over one year, an ... | 2009 | 19958577 |
| estimated epidemiologic parameters and morbidity associated with pandemic h1n1 influenza. | in the face of an influenza pandemic, accurate estimates of epidemiologic parameters are required to help guide decision-making. we sought to estimate epidemiologic parameters for pandemic h1n1 influenza using data from initial reports of laboratory-confirmed cases. | 2010 | 19959592 |
| respiratory infection in institutions during early stages of pandemic (h1n1) 2009, canada. | outbreaks of respiratory infection in institutions in ontario, canada were studied from april 20 to june 12, 2009, during the early stages of the emergence of influenza a pandemic (h1n1) 2009. despite widespread presence of influenza in the general population, only 2 of 83 outbreaks evaluated by molecular methods were associated with pandemic (h1n1) 2009. | 2009 | 19961686 |
| cost analysis of public health influenza vaccine clinics in ontario. | public health in ontario delivers, promotes and provides each fall the universal influenza immunization program. this paper addresses the question of whether ontario public health agencies are able to provide the influenza immunization program within the ministry of health fiscal funding envelope of $5 per dose. | 2009 | 19994733 |
| barriers to acceptance of self-sampling for human papillomavirus across ethnolinguistic groups of women. | immigrant and low socio-economic (ses) women in north america underutilize papanicolaou screening. vaginal swab self-sampling for oncogenic human papillomavirus (hpv) has the potential to increase cervical cancer screening participation. the purpose of this qualitative study was to understand the perceptions of lower ses and immigrant women regarding self-sampling for hpv. | 2009 | 19994740 |
| comparison of two heights for forward-placed trunk support with standing work. | two forward-placed supports with different heights are investigated using human motion capture and emg. ten male participants stood in 10 degrees increments of trunk flexion between 0 and 40 degrees for three conditions; leaning on a desk adjusted to the height of the pelvis, leaning on a prototype support at the height of the sternum and with no external support. low back and hip extensor muscle activity was reduced by an average 60% with leaning against the prototype compared to the no-support ... | 2010 | 20004362 |
| the pandemic influenza planning process in ontario acute care hospitals. | there will be little time to prepare when an influenza pandemic strikes; hospitals need to develop and test pandemic influenza plans beforehand. | 2010 | 20022406 |
| air pollution and pneumonia: the "old man" has a new "friend". | | 2010 | 20026751 |
| phase i/ii trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice-weekly methotrexate, and daily prednisone as therapy for metastatic breast cancer using vascular endothelial growth factor and soluble vascular endothelial growth factor receptor levels as markers of response. | purpose preclinical studies indicate that metronomic chemotherapy is antiangiogenic and synergistic with other antiangiogenic agents. we designed a phase i/ii study to evaluate the safety and activity of adding dalteparin and prednisone to metronomic cyclophosphamide and methotrexate in women with measurable metastatic breast cancer (mbc). patients and methods patients received daily dalteparin and oral cyclophosphamide, twice-weekly methotrexate, and daily prednisone (dalcmp). the primary study ... | 2010 | 20026801 |
| food reservoir for escherichia coli causing urinary tract infections. | closely related strains of escherichia coli have been shown to cause extraintestinal infections in unrelated persons. this study tests whether a food reservoir may exist for these e. coli. isolates from 3 sources over the same time period (2005-2007) and geographic area were compared. the sources comprised prospectively collected e. coli isolates from women with urinary tract infection (uti) (n = 353); retail meat (n = 417); and restaurant/ready-to-eat foods (n = 74). e. coli were evaluated for ... | 2010 | 20031048 |
| the mindsets of medical education leaders: how do they conceive of their work? | how a leader perceives his or her organization affects that individual's decision making and beliefs about the best way to influence it. the goal of this study was to understand how medical education leaders conceive of their work. | 2010 | 20042823 |
| development of a critical care triage protocol for pandemic influenza: integrating ethics, evidence and effectiveness. | | 2009 | 20057230 |
| preliminary studies into the characterization of chemical markers of decomposition for geoforensics. | in this paper, we report the results of our preliminary studies into chemical characterization of the fluids produced during decomposition in the absence of a soil matrix. pig (sus domestica) carcasses were used to model the human decomposition process in two separate locations, western australia (perth) and canada (oshawa). analysis involved simple dilution and filtration of the decomposition fluids followed by gas chromatography-mass spectrometry. several previously unreported compounds were d ... | 2010 | 20070470 |
| when a community hospital becomes an academic health centre. | with the burgeoning role of distributed medical education and the increasing use of community hospitals for training purposes, challenges arise for undergraduate and postgraduate programs expanding beyond traditional tertiary care models. it is of vital importance to encourage community hospitals and clinical faculty to embrace their roles in medical education for the 21st century. with no university hospitals in northern ontario, the northern ontario school of medicine and its educational partn ... | 2010 | 20070926 |
| functional comparison of hemoglobin purified by different methods and their biophysical implications. | hemoglobin (hb) that is purified from red blood cells (rbcs) is commonly subjected to harsh processing conditions, such as high temperatures and extensive column separation, which may damage the hb by altering the heme prosthetic group and/or the hb protein structure. in this study, bovine and human hb purified by tangential flow filtration (tff) was compared to commercial preparations of human hb (hemosol, inc., toronto, canada) and bovine hb (biopure, inc., cambridge, ma). purified hbs were ch ... | 2010 | 20073089 |
| trace elements in recent groundwater of an artesian flow system and comparison with snow: enrichments, depletions, and chemical evolution of the water. | snow samples collected from hand-dug pits at two sites in simcoe county, ontario, canada were analysed for major and trace elements using the clean lab methods established for polar ice. potentially toxic, chalcophile elements are highly enriched in snow, relative to their natural abundance in crustal rocks, with enrichment factor (ef) values (calculated using sc) in the range 107 to 1081 for ag, as, bi, cd, cu, mo, pb, sb, te, and zn. relative to m/sc ratios in snow, water samples collected at ... | 2010 | 20082015 |
| detection and characterization of clostridium difficile in retail chicken. | this study was designed to evaluate the prevalence of clostridium difficile contamination of retail chicken. | 2010 | 20102510 |
| school-based influenza vaccine delivery, vaccination rates, and healthcare use in the context of a universal influenza immunization program: an ecological study. | influenza vaccines are universally funded in ontario, canada. some public health units (phus) vaccinate children in schools. we examined the impact of school-based delivery on vaccination rates and healthcare use of the entire population over seven influenza seasons (2000-2007) using population-based survey and health administrative data. school-based vaccination was associated with higher vaccination rates in school-age children only. doctors' office visits were lower for phus with school-based ... | 2010 | 20109594 |
| an exploration of ruling relations and how they organize and regulate nursing education in the high-fidelity patient simulation laboratory. | recently, schools of nursing have adopted the use of high-fidelity human patient simulators in laboratory settings to teach nursing. although numerous articles document the benefits of teaching undergraduate nursing students in this way, little attention has been paid to the discourses and texts organizing this approach. this institutional ethnography uses the critical feminist sociology of dorothy e. smith to examine the literature and interviews with practical and bachelor of science in nursin ... | 2010 | 20137031 |
| palliating a pandemic: "all patients must be cared for". | in the event of an overwhelming influenza pandemic, many health care systems will implement a triage system that would potentially deny critical care treatment to some seriously ill patients. although all triage systems have guaranteed palliative care for those who are denied critical care, no jurisdiction has yet developed a plan to accommodate the anticipated "surge" in demand for palliative care. the authors present a mathematical and ethical justification for a palliative care surge plan and ... | 2010 | 20152591 |
| novel duplex real-time pcr assay detects bordetella holmesii in specimens from patients with pertussis-like symptoms in ontario, canada. | bordetella holmesii is a human pathogen found mainly in immunocompromised patients. a specific real-time pcr assay was developed and successfully used to identify specimens from which b. holmesii was misidentified as bordetella pertussis and to establish the prevalence of b. holmesii in ontario patients with pertussis-like symptoms. | 2010 | 20181919 |
| tularemia, plague, yersiniosis, and tyzzer's disease in wild rodents and lagomorphs in canada: a review. | information related to infection of wild rodents or lagomorphs in canada by francisella tularensis, yersinia pestis, other yersinia spp., and clostridium piliforme was searched for this study. reports on tularemia in humans linked to these species came from diagnostic databases, literature, wildlife health specialists, and public health agencies. tularemia has been diagnosed in 8 species of wild rodent and 2 species in the genus lepus in canada. tularemia occurred in wild animals, or in humans a ... | 2009 | 20190973 |
| evaluation of pneumonia severity and acute physiology scores to predict icu admission and mortality in patients hospitalized for influenza. | the demand for inpatient medical services increases during influenza season. a scoring system capable of identifying influenza patients at low risk death or icu admission could help clinicians make hospital admission decisions. | 2010 | 20221431 |
| constitutionality of gay blood donor ban challenged in court. | kyle freeman, a gay canadian man, is challenging in the ontario superior court of justice the constitutionality of the canadian blood services' (cbs') lifetime ban on men who have sex with men (msm). he claims that the questionnaire used by the agency to screen out unsuitable donors violates his equality rights' under the canadian charter of rights and freedoms (charter). | 2009 | 20225506 |
| tp53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors. | purpose choroid plexus carcinomas are pediatric tumors with poor survival rates and a strong, but poorly understood, association with li-fraumeni syndrome (lfs). currently, with lack of biologic predictors, most children are treated with aggressive chemoradiation protocols. patients and methods we established a multi-institutional tissue and clinical database, which enabled the analysis of specific alterations of the tp53 tumor suppressor and its modifiers in choroid plexus tumors (cpts). we con ... | 2010 | 20308654 |
| attitudes of canadian dairy farmers toward a voluntary johne's disease control program. | the success of johne's disease (jd) control programs based on risk assessment (ra) depends on producers' compliance with suggested management practices. one objective of this study was to describe the perception of participating canadian dairy farmers of the impact of jd, the ra process, and suggested management strategies. the second objective was to describe the cost of changes in management practices following the ra. a telephone survey was conducted with 238 dairy farmers in ontario, manitob ... | 2010 | 20338426 |
| pandemic (h1n1) 2009 risk for nurses after trivalent vaccination. | | 2010 | 20350398 |
| impacts of adjacent land use and isolation on marsh bird communities. | over the next half century the human population is expected to grow rapidly, resulting in the conversion of rural areas into cities. wetlands in these regions are therefore under threat, even though they have important ecosystem services and functions. many obligate marsh-nesting birds in north america have shown declines over the past 40 years, and it is important to evaluate marsh bird community response to increased urbanization. we surveyed 20 coastal marshes in southern ontario, canada, and ... | 2010 | 20358198 |
| spatial and temporal clustering of calcium oxalate and magnesium ammonium phosphate uroliths in dogs living in ontario, canada between 1998 and 2006. | using the spatial scan statistic with a bernoulli model, in a comparison of the two most common canine uroliths, calcium oxalate (caox) and magnesium ammonium phosphate (struvite) we determined whether there was evidence of spatial and/or temporal clustering of each urolith type based on canine submissions from ontario to the canadian veterinary urolith centre (cvuc) between 1998 and 2006. during this period, there were 10,478 canine submissions, excluding cases that were identified as recurrent ... | 2010 | 20359758 |
| nursesfortomorrow: a proactive approach to nursing resource analysis. | this paper describes the background, development, implementation and utilization of nursesfortomorrow (n4t), a practical and comprehensive nursing human resources analysis method to capture regional, institutional and patient care unit-specific actual and predicted nurse vacancies, nurse staff characteristics and nurse staffing changes. reports generated from the process include forecasted shortfalls or surpluses of nurses, percentage of novice nurses, occupancy, sick time, overtime, agency use ... | 2010 | 20383079 |
| association between the 2008-09 seasonal influenza vaccine and pandemic h1n1 illness during spring-summer 2009: four observational studies from canada. | in late spring 2009, concern was raised in canada that prior vaccination with the 2008-09 trivalent inactivated influenza vaccine (tiv) was associated with increased risk of pandemic influenza a (h1n1) (ph1n1) illness. several epidemiologic investigations were conducted through the summer to assess this putative association. | 2010 | 20386731 |
| the occurrence of campylobacter in river water and waterfowl within a watershed in southern ontario, canada. | quantitative pcr and a culture method were used to investigate campylobacter occurrence over 3 years in a watershed located in southern ontario, canada that is used as a source of drinking water. | 2010 | 20408936 |
| epidemiology of influenza-associated hospitalization in adults, toronto, 2007/8. | the purpose of this investigation was to identify when diagnostic testing and empirical antiviral therapy should be considered for adult patients requiring hospitalization during influenza seasons. during the 2007/8 influenza season, six acute care hospitals in the greater toronto area participated in active surveillance for laboratory-confirmed influenza requiring hospitalization. nasopharyngeal (np) swabs were obtained from patients presenting with acute respiratory or cardiac illness, or with ... | 2010 | 20428910 |
| psychometric properties of a peer-assessment program to assess continuing competence in physical therapy. | the college of physiotherapists of ontario implemented an onsite assessment to evaluate the continuing competence of physical therapists. | 2010 | 20430949 |
| six-degree-of-freedom whole-body vibration exposure levels during routine skidder operations. | this research focuses on quantifying six-degree-of-freedom (6-dof) whole-body vibration (wbv) exposure levels that occur in northern ontario skidders during routine field operating tasks. 6-dof vibration running root-mean-square (rms) acceleration levels at the operator/seat interface were determined for eight skidders while driving loaded, driving unloaded, picking up a load, dropping off a load and ploughing logs under field operating conditions. the acceleration data were weighted in accordan ... | 2010 | 20432089 |
| human health risk assessment from exposure to trihalomethanes in canadian cities. | lifetime exposure to trihalomethanes (thms) through ingestion, inhalation and dermal contacts may pose risks to human health. current approaches may under predict thms exposure by using thms in cold water during showering and bathing. warming of chlorinated water during showering may increase thms formation through reactions between organics and residual chlorine, which can increase human health risks. in this study, thms concentrations in shower water were estimated using thms rate increase mod ... | 2010 | 20434775 |
| examination of adipocere formation in a cold water environment. | adipocere is a late-stage postmortem decomposition product that forms from the lipids present in soft tissue. its formation in aquatic environments is typically related to the presence of a moist, warm, anaerobic environment, and the effect of decomposer microorganisms. the ideal temperature range for adipocere formation is considered to be 21-45 degrees c and is correlated to the optimal conditions for bacterial growth and enzymatic release. however, adipocere formation has been reported in coo ... | 2010 | 20437052 |
| the demonstration projects: creating the capacity for nursing health human resource planning in ontario's healthcare organizations. | timely access to healthcare services requires the right number, mix and distribution of appropriately educated nurses, physicians and other healthcare professionals. in ontario, as in several other jurisdictions, changing demographics, patterns of health service utilization and an aging workforce have created challenges related to the supply of nurses available now and in the future to deliver quality patient care. from 2006 to 2009, the nursing secretariat (ns) of ontario's ministry of health a ... | 2010 | 20463442 |
| the nursing human resource planning best practice toolkit: creating a best practice resource for nursing managers. | evidence of acute nursing shortages in urban hospitals has been surfacing since 2000. further, new graduate nurses account for more than 50% of total nurse turnover in some hospitals and between 35% and 60% of new graduates change workplace during the first year. critical to organizational success, first line nurse managers must have the knowledge and skills to ensure the accurate projection of nursing resource requirements and to develop proactive recruitment and retention programs that are eff ... | 2010 | 20463445 |
| advancing nursing leadership in long-term care. | nurses working in the long-term care (ltc) sector face unique workplace stresses, demands and circumstances. designing approaches to leadership training and other supportive human-resource strategies that reflect the demands of the ltc setting fosters a positive work life for nurses by providing them with the skills and knowledge necessary to lead the care team and to address resident and family issues. through the st. joseph's health centre guelph demonstration site project, funded by the nursi ... | 2010 | 20463447 |
| collaboration to change the landscape of nursing: a journey between urban and remote practice settings. | university health network (uhn) became a demonstration site to test a health human resource planning model to foster inter-organizational collaboration, knowledge transfer and exchange of nurses between an urban academic health science centre and a remote region in northern ontario. funding support was provided by the ontario ministry of health and long-term care. the partnership between uhn, weeneebayko health ahtuskaywin (wha) and james bay general hospital (jbgh) addressed retention, recruitm ... | 2010 | 20463448 |
| workforce demand forecaster tool: health human resources' recruitment crystal ball? | | 2010 | 20463452 |
| collaborative health human resource planning: a retention and recruitment initiative--full time, shared and unionized positions. | | 2010 | 20463453 |
| a collaborative approach in the waterloo region supporting health human resources planning. | | 2010 | 20463455 |
| rural routes: recruitment and retention in rural areas for health human resources. | | 2010 | 20463459 |
| optimal pandemic influenza vaccine allocation strategies for the canadian population. | the world is currently confronting the first influenza pandemic of the 21(st) century. influenza vaccination is an effective preventive measure, but the unique epidemiological features of swine-origin influenza a (h1n1) (ph1n1) introduce uncertainty as to the best strategy for prioritization of vaccine allocation. we sought to determine optimal prioritization of vaccine distribution among different age and risk groups within the canadian population, to minimize influenza-attributable morbidity a ... | 2010 | 20463898 |
| measuring attitudes toward stuttering: english-to-french translations in canada and cameroon. | a field test of a survey instrument under development, the public opinion survey of human attributes, experimental edition (posha-e), designed to investigate language-, culture-, and nation-specific public opinions about stuttering is reported. this investigation compared english and french versions of the posha-e in widely disparate cultures to explore country versus language influences. | 2010 | 20466386 |
| potential pediatric intensive care unit demand/capacity mismatch due to novel ph1n1 in canada. | to investigate the possibility of pediatric intensive care unit shortfalls, using pandemic models for a range of attack rates and durations. the emergence of the swine origin ph1n1 virus has led to concerns about shortfalls in our ability to provide pediatric ventilation and critical care support. | 2010 | 20473239 |
| pyrethroid pediculicide resistance of head lice in canada evaluated by serial invasive signal amplification reaction. | most people in the united states and canada with pediculosis will be treated with neurotoxic pediculicides containing pyrethrins or pyrethroids. their widespread use led to significant resistance reported from various countries. although treatment failures are frequently observed in canada, the resistance frequency to pyrethroid pediculicide of human head lice (pediculus humanus capitis) has not been determined. | 2010 | 20487671 |
| impact of patient education on knowledge of influenza and vaccine recommendations among pregnant women. | to determine whether providing an information pamphlet in the antenatal clinic improves women's knowledge about influenza and vaccine recommendations during pregnancy. | 2010 | 20500967 |
| the 6th hupo antibody initiative (hai) workshop: sharing data about affinity reagents and other recent developments. september 2009, toronto, canada. | the human antibody initiative (hai) aims to promote and facilitate the use of antibodies for proteomics research. the 6th workshop for the hupo antibody initiative (hai) held in september 2009 was co-chaired by michael snyder and mathias uhlen and discussed several aspects of antibody production, their validation, and attempts to standardise this process, in particular, when subsequently described in the literature. an update on the progress of the human protein atlas was also presented to the a ... | 2010 | 20514648 |
| the 4th human kidney and urine proteome project (hkupp) workshop. 26 september 2009, toronto, canada. | the human kidney and urine proteome project (hkupp) was initiated to promote proteomics research in the nephrology field, to better understand kidney functions as well as pathogenic mechanisms of kidney diseases, and to define novel biomarkers and therapeutic targets. the 4th workshop held in september 2009 discussed problems of proteomics analysis for kidney tissues and urine samples and a standard protocol for collection, storage and protein concentration of urine samples was decided upon. | 2010 | 20514649 |
| human brain proteome project - 12th hupo bpp workshop. 26 september 2009, toronto, canada. | the hupo brain proteome project (hupo bpp) held its 12th workshop in toronto on 26 september 2009 prior to the hupo viii world congress. the principal aim of this project is to obtain a better understanding of neurodiseases and ageing, with the ultimate objective of discovering prognostic and diagnostic biomarkers, in addition to the development of novel diagnostic techniques and new medications. the attendees came together to discuss progress in the human clinical neuroproteomics and to define ... | 2010 | 20514650 |
| plasma cystatin c and acute kidney injury after cardiopulmonary bypass. | little is known about the performance of plasma cystatin c (cysc) in patients undergoing cardiopulmonary bypass (cpb) and its utility in the early diagnosis of acute kidney injury (aki). in this post hoc analysis, the goal was to determine whether plasma cystatin c, measured 2 hours after the conclusion of cpb, is a reliable marker of aki. | 2010 | 20522534 |
| student declarations of absence in lieu of doctor's notes. | | 2010 | 20527078 |
| prostate-specific antigen test result interpretation when combined with risk factors for recommendation of biopsy: a survey of urologist's practice patterns. | recent data have suggested historical cutoff levels for prostate cancer (pc) screening using a prostate-specific antigen (psa) level ≤ 4 ng/ml may no longer be appropriate with cancer detected at lower levels, particularly in younger men. our aim was to conduct a contemporary survey of urologist's practice patterns toward pc detection, specifically focusing on factors determining the decision to recommend ultrasound-guided biopsy (trus-bx). | 2011 | 20544283 |
| factorial analysis of trihalomethanes formation in drinking water. | disinfection of drinking water reduces pathogenic infection, but may pose risks to human health through the formation of disinfection byproducts. the effects of different factors on the formation of trihalomethanes were investigated using a statistically designed experimental program, and a predictive model for trihalomethanes formation was developed. synthetic water samples with different factor levels were produced, and trihalomethanes concentrations were measured. a replicated fractional fact ... | 2010 | 20572463 |
| cost effectiveness of insulin glargine plus oral antidiabetes drugs compared with premixed insulin alone in patients with type 2 diabetes mellitus in canada. | several treatment options are available for patients with type 2 diabetes mellitus who are making the transition from oral antidiabetes drugs (oads) to insulin. two options currently recommended by the canadian diabetes association for initiating insulin therapy in patients with type 2 diabetes who are no longer responsive to oads alone are insulin glargine plus oads, and premixed insulin therapy only. because of differences in efficacy, adverse events (such as hypoglycaemia) and acquisition cos ... | 2010 | 20578781 |
| outside looking in: the lived experience of adults with prematurely born siblings. | siblings have unique relationships; however, not all sibling relationships are typical. in north america, the preterm birth rate ranks second only to africa in a global climate of rising preterm birth rates. a paucity of literature exists for sibling relationships when one sibling is born prematurely. in this hermeneutic phenomenological study, we explored the lived experience of adult siblings with prematurely born, young adult brothers and sisters who subsequently developed disabilities. the 2 ... | 2010 | 20581076 |
| determining rates of hepatitis c in a clozapine treated cohort. | to determine the prevalence rates of hepatitis c in patients with schizophrenia and schizoaffective disorder being treated with clozapine. | 2010 | 20605572 |
| knowledge and attitudes toward food safety and use of good production practices among canadian broiler chicken producers. | provincial broiler-chicken marketing boards in canada have recently implemented an on-farm food safety program called safe, safer, safest. the purpose of this study was to measure broiler chicken producers' attitudes toward the program and food safety topics and use of highly recommended good production practices (gpp). mailed and web-based questionnaires were administered to all producers registered in british columbia, ontario, and quebec in 2008. the response percentage was 33.2% (642 of 1,93 ... | 2010 | 20615340 |
| prevalence and antimicrobial resistance in campylobacter spp. isolated from retail chicken in two health units in ontario. | campylobacter is an important enteric pathogen of humans and can cause diarrhea, fever, and abdominal pain. campylobacter infections have frequently been associated with the handling and consumption of raw and undercooked poultry. antimicrobial resistance among campylobacter strains is of concern in the treatment of campylobacteriosis in vulnerable populations. a 2-year multidisciplinary study was conducted in the perth and wellington-dufferin-guelph public health units in ontario, canada, to in ... | 2010 | 20615345 |
| 8th hupo world congress: the human disease glycomics/proteomics initiative (hgpi) session 26 september 2009, toronto, canada. | the human disease glycomics/proteomics initiative (hgpi) session at the hupo world congress was held in toronto on 26 september 2009. in this report, we summarize the presentation of the hgpi workshop as follows: (i) the results of the past hgpi pilot studies (first and second) in which we analyzed n- and o-linked glycans using standard glycoproteins (i.e. first: n-linked glycan analysis of transferrin and igg; second: o-linked glycan analysis of iga). (ii) the recent progresses of the current h ... | 2010 | 20623475 |
| prevalence of dietitian burnout. | burnout is the result of unmanaged stress that has been shown to affect those working in the healthcare professions. although much research has been conducted on burnout among nurses, physicians and other health professionals, there is limited documentation on the phenomenon among dietitians. the purpose of this study was to establish the prevalence of burnout among dietitians in ontario, canada, determine the demographic variables associated with burnout, and compare these results with burnout ... | 2010 | 20642639 |
| is a mass immunization program for pandemic (h1n1) 2009 good value for money? evidence from the canadian experience. | in response to the pandemic h1n1 influenza 2009 outbreak, many jurisdictions undertook mass immunization programs that were among the largest in recent history. the objective of this study was to determine the cost-effectiveness of the mass h1n1 immunization program in ontario, canada's most populous province (population 13,000,000). this analysis suggests that a mass immunization program as carried out in ontario and many other high-income health care systems in response to h1n1 2009 was effect ... | 2010 | 20643091 |
| predictors of universal influenza vaccination uptake in grades 1 and 2 toronto school children: effective vaccination strategies should not end with at risk children. | the first population-based survey to determine predictors of influenza vaccination among children in a major metropolitan city with access to publicly funded health care and a universal influenza immunization program (uiip). previously collected demographic and health related data from 5619 school children aged 5-9 in toronto, in 2006 were used to predict influenza vaccination. vaccination was more likely in children with current asthma (or 1.44, 95%cl 1.19-1.75), a high volume of contacts with ... | 2010 | 20655400 |
| use of intravenous immune globulin in the icu: a retrospective review of prescribing practices and patient outcomes. | intravenous immune globulin (ivig) is a pooled human blood product. much of ivig use in canada is prescribed for 'unlabelled' or 'off-label' indications. due to costs, risk of use and limited supply, knowledge about the use of ivig is important. we collected data regarding the usage of ivig and outcomes of patients receiving ivig in the intensive care units (icus) of two community and three academic hospitals. | 2010 | 20663105 |
| interlaboratory variation in heparin monitoring: lessons from the quality management program of ontario coagulation surveys. | unfractionated heparin (ufh) monitoring is subject to substantial interlaboratory variation. we analysed results of annual coagulation surveys administered by the quality management program - laboratory services (toronto, on, canada) from 2003 to 2007 to evaluate variation in ufh monitoring across ontario. participating laboratories performed an activated partial thromboplastin time (aptt) utilising their local methodology on lyophilised human plasma spiked with ufh. in the 2006 and 2007 surveys ... | 2010 | 20664895 |
| gene dosage of the common variant 9p21 predicts severity of coronary artery disease. | the purpose of this study was to test the hypothesis that 9p21 gene dosage determines the severity of coronary artery disease (cad). | 2010 | 20670758 |
| the 9p21 locus and coronary heart disease: initiator, promoter, or precipitator? | | 2010 | 20670759 |
| longitudinal investigation of clostridium difficile shedding in piglets. | a longitudinal study of clostridium difficile colonization in piglets was performed on a conventional swine farm in ontario, canada. fecal samples were collected from 10 sows prior to their expected farrowing date, and then from all their piglets on days 2, 7, 30, 44 and 62 of life. c. difficile was isolated from 4/10 (40%) of sows prior to farrowing, 90/121 (74%) piglets on day 2, 66/117 (56%) on day 7, 45/113 (40%) on day 30, 23/101 (23%) on day 44 and 2/54 (3.7%) on day 62. there was a signif ... | 2010 | 20708700 |
| seasonal influenza and vaccination coverage. | seasonal influenza represents a considerable public health burden, and annual vaccination represents the most effective preventive strategy for amelioration of this problem. certain groups are at greatest risk, such as the young, the elderly, pregnant women, and those with chronic underlying medical conditions: the high-risk groups. traditionally, annual vaccination has been targeted to people classified as being at high risk, particularly the elderly, but in recent years, there has been a broad ... | 2010 | 20713259 |
| neonates investigated for influenza-like illness during the outbreak of pandemic h1n1 2009: trivial infections but major triage implications. | we report eight cases of neonates (from birth to 25 days) admitted to the neonatal service of a teaching hospital with influenza-like illness during the outbreak of pandemic h1n1 2009, and discuss their management and infection control issues. empirical antibiotics were often promptly initiated and timely stopped when sepsis was ruled out. also, there was no pandemic h1n1-09 but influenza a (h3n2, n = 1), parainfluenza (type 3, n = 3) and respiratory syncytial virus (n = 1) have been isolated. t ... | 2010 | 20814838 |
| a retrospective economic analysis of the ontario red fox oral rabies vaccination programme. | ontario initiated a red fox (vulpes vulpes) oral rabies vaccination (orv) programme in 1989. this study utilized a benefit-cost analysis to determine if this orv programme was economically worthwhile. between 1979 and 1989, prior to orv baiting, the average annual human post-exposure treatments, positive red fox rabies diagnostic tests and indemnity payments for livestock lost to rabies were 2248, 1861 and $246,809, respectively. after baiting, from 1990 to 2000, a 35%, 66% and 41% decrease in p ... | 2011 | 20819201 |
| cost-effectiveness of ontario's pandemic vaccine program. | | 2011 | 20831912 |
| from places to flows. international secondary migration and birth outcomes. | research on the health status of international migrants to industrialised countries in general, and on perinatal outcomes in particular, has assumed an interpretative model based on primary migration, characterised by one permanent cross-border movement from the migrant's country of birth. however, many migrants experience more complex migration patterns that may also be associated with human health. secondary migration, defined as a migration from a country of residence other than the country w ... | 2010 | 20850920 |
| the long-term effects of water fluoridation on the human skeleton. | municipal water fluoridation has notably reduced the incidence of dental caries and is widely considered a public health success. however, ingested fluoride is sequestered into bone, as well as teeth, and data on the long-term effect of exposure to these very low doses of fluoride remain inconclusive. epidemiological studies suggest that effects of fluoride on bone are minimal. we hypothesized that the direct measurement of bone tissue from individuals residing in municipalities with and without ... | 2010 | 20858781 |
| pathologic assessment of radiofrequency ablation of pulmonary metastases. | to evaluate pathologically the effectiveness of radiofrequency (rf) ablation in the treatment of pulmonary metastases. | 2010 | 20884239 |