| rational treatment of acid-base disorders. | acid-base derangements are encountered frequently in clinical practice and many have life-threatening implications. treatment is dependent on correctly identifying the acid-base disorder and, whenever possible, repairing the underlying causal process. bicarbonate is the agent of choice for the treatment of acute metabolic acidosis. controversy surrounds the use of alkali therapy in lactic acidosis and diabetic ketoacidosis, but bicarbonate should clearly be administered for severe acidosis. in m ... | 1997 | 2196165 |
| increased activity of digoxin-like substance in low-renin hypertension in acromegaly. | arterial hypertension is common in acromegaly, but the pathogenesis of this complication remains unknown. to determine the role of an endogenous na,k pump inhibitor/digoxin-like substance (dls) in the pathogenesis of hypertension in acromegaly 76 subjects: 28 with acromegaly, 20 with essential hypertension and 28 healthy controls were studied. serum dls was measured with the use of radioimmunoassay and bioassay by the inhibition of digoxin-sensitive erythrocyte 86-rb uptake. in acromegaly, the a ... | 1997 | 2196126 |
| nonvisualized gallbladder by cholecystosonography. | to further define the significance of gallbladder nonvisualization by cholecystosonography, we studied follow-up data on 25 consecutive patients in whom the gallbladder could not be identified despite adequate fasting. in one patient, intravenous cholangiography demonstrated a large gallbladder but no gallstones. in the 24 cases for which a pathoanatomic diagnosis was established, all but two had diseased gallbladders with obliteration of the lumen. this 88% accuracy for positive prediction conf ... | 1998 | 107735 |
| neonatal diagnosis of familial dysautonomia. | the serious prognostic implications of familial dysautonomia (fd) for the affected individual and his family make early definitive diagnosis mandatory. familial dysautonomia has rarely been diagnosed in the neonatal period in hitherto unaffected families. we describe here three such newborn patients to reinforce the limited data available on this subject. in spite of the variability of expression and the incompleteness of the manifestations of fd in the neonatal period, as well as the presence o ... | 1998 | 108661 |
| [indications for operation of chronically recurring juvenile appendicitis]. | | 1998 | 108578 |
| [the overdiagnosed patient--a legend?]. | | 1998 | 108562 |
| [hyperthermia and irradiation for tumor treatment (proceedings)]. | | 1998 | 108547 |
| community health. | | 1998 | 107499 |
| treatment of perennial rhinitis with flunisolide corticosteroid spray. | flunisolide nasal spray was compared to its propylene and polyethylene glycol vehicle in a randomized double-blind study of 20 adult patients with perennial rhinitis. after a two-week baseline period patients received either active flunisolide 50 microgram q.i.d. or placebo for four weeks. laboratory studies included serum 8 a.m. cortisols, nasal air-flow measurements and nasal smears for eosinophils and fungi. patients kept daily symptom diaries. there was no difference between active and place ... | 1998 | 106747 |
| [ix. randomized study of the effect of nitroglycerin on ck and ck-mb infarct size. preliminary report (author's transl)]. | in 38 patients with acute myocardial infarction the effect of nitroglycerin on infarct size was studied. patients were randomized into two groups. 16 patients received continuous nitroglycerin infusions of 0.6 to 6.0 mg/h (mean 2.3 mg/h) over a 48 h period, 22 patients received no specific therapy and served as control. nitroglycerin was given in the mean 12 +/- 5 (+/- 1 sd) hours following onset of chest pain and 8 +/- 5 after the increase of ck values. infarct size was determined according to ... | 1998 | 108461 |
| liver function values in adults receiving total parenteral nutrition. | a retrospective review was made of results of conventional liver function tests in adult patients who received fat-free total parenteral nutrition (tpn) for two weeks or longer and who did not have other obvious causes for liver function abnormalities. a "meaningful" increase (greater than or equal 50% increase above baseline pre-tpn value) in sgot levels was noted in 68% of patients, in alkaline phosphatase levels in 54%, and in serum bilirubin levels in 21% of patients. the median peak values ... | 1998 | 108412 |
| otolaryngological features of 'malformation syndrome with cryptophthalmos'. | anomalies of the nose, larynx and oral cavity are described in two patients with cryptophthalmos. a teratogen acting at the time of lid fold formation is probably responsible for the ocular and systemic involvement which are primarily ectodermal defects with some mesodermal involvement. | 1998 | 108347 |
| clinical measurement of iron status. | | 1998 | 107345 |
| applications of real-time ultrasound in obstetrics: the linear and dynamically focused phased arrays. | real-time ultrasound is a dynamic imaging technique that allows in utero orientation to the fetus. it permits rapid and efficient examination of fetal anatomy and provides a dynamic assessment of fetal well-being. the energy dissipation can be comparable to that in conventional ultrasonic b-mode scanning. we have used both linear and dynamically focused phased arrays for fetal examinations in conjunction with conventional gray scale b-mode scanners. the sophisticated phased-array real-time syste ... | 1998 | 108306 |
| hla: a super supergene. | | 1998 | 108234 |
| optic chiasmatic glioma in children. | we reviewed the records of 29 patients with optic nerve or chiasm glioma, or both, seen from 1955 to 1966. sixteen patients were girls and 13 were boys. at the time of diagnosis, 14 patients were less than 2 years old. optic atrophy was the most frequently seen physical finding, present in 26 of 29 patients. twelve patients had diencephalic syndrome (41%). proptosis was seen in eight. eleven patients (38%) had associated neurofibromatosis. pneumoencaphalogram was done on 26 patients and was abno ... | 1998 | 107806 |
| a direct method for determining dopamine synthesis and output of dopamine metabolites from brain in awake animals. | | 1998 | 107275 |
| the health care industry: a case study and future policy issues. | | 1998 | 107218 |
| a computerized reference laboratory. | | 1998 | 106229 |
| ribosomal dna in drosophila melanogaster. i. isolation and characterization of cloned fragments. | | 1998 | 106128 |
| altered mitochondrial metabolism in circulatory shock. | | 1998 | 19942 |
| fifty years of international control of dependence-producing drugs. | | 1998 | 121366 |
| "lerne, and gladly teche"--a view of the vietnam medical education project. | | 1998 | 106337 |
| expectations: do we always agree? care of the child with cancer. | | 1998 | 107940 |
| from earlier pages--the american journal of roentgenology. | | 1998 | 104589 |
| recent developments in diabetes research. | | 1999 | 97046 |
| [automated information system as a method of studying and preventing morbidity among workers in the petroleum industry]. | | 1999 | 2151192 |
| [contribution of divalent cations to the maintenance of membrane potentials in the oocytes of pleurodeles waltlii michah (amphibia, urodela)]. | when the external concentration of ca and mg is changed, the oocyte membrane potential, in the urodela amphibian: pleurodeles waltlii, is not significantly modified. the addition of chelator agents, egta and edta in ca, mg free steinberg solution promotes a membrane depolarisation and the rise of membrane conductance. it is concluded that divalent ions ca++ and mg++ are needed to maintain a potential difference between internal and external medium of the oocyte. | 1999 | 96993 |
| [ph-potentiometric study of 1-isadrine, 1-teranole and related compounds]. | | 1999 | 18365 |
| dynamics of correlated genetic systems. iv. multilocus effects of ethanol stress environments. | four replicate populations of drosophila melanogaster, two reared on medium supplemented with ethanol and two reared on standard medium, were electrophoretically monitored for 28 generations. during the first 12 generations, allelic, genotypic and gametic frequencies were determined for eight polymorphic enzymes: got, alpha-gpdh, mdh, adh, to, e6, ec and odh. samples from generation 18 and 28 were electrophoretically typed for adh and alpha-gpdh. in addition, samples from generation 27 were anal ... | 1999 | 103779 |
| f cells in gynaecologic malignancy. | red cells containing hb f (f cells) were detected by immunofluorescence using a specific antiserum. in normal persons, the number of f cells was 2.5 +/- 1.1%. a significantly increased number of f cells was found in 65% of patients with cancer of the ovary, 69% of patients with cancer of the endometrium and in 22% of patients with cancer of the cervix. highest values were obtained in cancer of the ovary and endometrium. there was no correlation between the number of f cells and stage of disease ... | 1999 | 94026 |
| [iontophoresis in rheumatic diseases]. | | 1999 | 316947 |
| purification of an acidic nuclear protein antigen and demonstration of its antibodies in subsets of patients with sicca syndrome. | | 1999 | 408417 |
| x-ray absorption spectroscopy of biological molecules. | | 1999 | 96725 |
| [congenital glaucoma in hurler's syndrome and in lowe's syndrome. clinical and electron microscopy findings]. | 2 cases of congenital glaucoma combined with a general metabolic disease are described. 1 patient displayed the symptoms of a mucopolysaccharidosis (hurler's syndrome), the other patient showed the characteristics of lowe's oculo-cerebrorenal syndrome. in both patients a surgical trabeculectomy was performed. the excised tissues were analysed by electron microscopy. distinct vacuolar or fibrillar deposits were observed in both cases in the trabecular region and in schlemm's canal. possibly, thes ... | 1999 | 96681 |
| diagnostic value of determinations of lysosomal hydrolases in csf of patients with neurological diseases. | the activities of four lysosomal acid hydrolases, beta-galactosidase, alpha-mannosidase at ph 4.5 and 5.5, n-acetyl-beta-glucosaminidase, and acid phosphatase, have been measured in serum and cerebrospinal fluid from 179 patients with different neurological diseases and from 20 healthy controls. in patients with tumours, decreased activity of beta-galactosidase was found in both serum and cerebrospinal fluid, and in patients with multiple sclerosis and collagen diseases, decreased activities of ... | 1999 | 96653 |
| the or nurse manager. blending an autocratic and democratic approach to lead effectively. | | 1999 | 2326857 |
| excessive pressure for respiratory therapy. | | 1999 | 116529 |
| [effect of imipramine on mitochondrial membrane lipids (proceedings)]. | | 1999 | 93912 |
| effect of provider attitudes in community health decision-making. | | 1999 | 4688479 |
| cervical smear contamination. | | 1999 | 93840 |
| phase and amplitude contrast in electron microscopy of stained biological objects. | for biological objects negatively stained with heavy atom material, electron microscope images show best contrast for image detail on the scale of 10--20 a when a small objective aperture is used. in images taken under the optimum phase contrast imaging conditions of scherzer, the required image detail is lost in unwanted noise. both of these conditions may be described in terms of phase contrast imaging for a thin phase object. calculations of image intensities and noise are reported for a mode ... | 1999 | 93821 |
| studies on the determination of plasma prolactin. | a double antibody solid-phase (dasp) and a plyethylene glycol (peg) radioimmunoassay method for plasma prolactin determination were developed and evaluated as to their reliability. the iodination of prolactin was carried out using a lactoperoxidase sorbent with iodination conditions being optimized by studying the effect of reaction buffer ph in the range 5.0--7.0 at two ionic strengths. with the dasp-technique, intra-assay coefficient of variation was 6% (n = 30) and the inter-assay coefficient ... | 1999 | 96520 |
| [use of the hour-glass method for the study of intestinal microflora]. | | 1999 | 89239 |
| how to write your first book. | many doctors have, at some time or other, the idea of writing a book. this article considers some of the practical problems involved, including dealing with publishers, the formulation of a book proposal, writing individual chapters and desirable features of computer software. | 1999 | 2640686 |
| total-body irradiation with 25-mv photons in advanced non-hodgkin's lymphoma and chronic lymphocytic leukemia. preliminary results and complications. | patients with chronic lymphocytic leukemia (cll) and non-hodgkin's lymphoma were treated with total-body irradiation (tbi). one group was treated after chemotherapy failed, while the other group received tbi initially. tbi was ineffective against cll after chemotherapy failed. all patients with lymphocytic lymphoma who initially responded to chemotherapy but later relapsed were helped by tbi, as were 88% of patients with previously untreated lymphocytic lymphomas. | 1999 | 96493 |
| [clinico-statistical study of materno-fetal isoimmunization in the clinica ostetrica e ginecologica of the university of modena from 1968 to 1976]. | | 1999 | 96389 |
| [diurnal variations in glucose tolerance in normal subjects and changes induced by oral glibenclamide]. | | 1999 | 96388 |
| [parenteral nutrition in acute uremia in the surgical patient]. | | 1999 | 96386 |
| case for diagnosis. | | 1999 | 96362 |
| [radiotoxic effects of tritium from tritiated water. study of lethal and mutagenic effects. inactivation of lysogenic bacteriophages by tritium decay (proceedings)]. | | 1999 | 93453 |
| properties of four molecular forms of n-acetyl-beta-d-hexosaminidase isolated from germinating seeds of fenugreek (trigonella foenum graecum). | | 1999 | 25183 |
| [economic crisis in public health in the capitalist countries]. | | 2000 | 97790 |
| some factors, influencing the sensitivity of the antibody screening the groupamatic 360 system. | | 2000 | 97759 |
| [problems of electrocardiographic and vectorcardigoraphic diagnosis in postero-basal myocardial infarct and in right branch block]. | | 2000 | 97684 |
| [relations between myopia, education and intelligence]. | | 2000 | 2189811 |
| [determination of serum digitoxin by means of a solid-phase enzyme-linked immunosorbent assay (author's transl)]. | a solid-phase elisa-technique for clinical applications is described. it requires little apparatus other than a photometer and allows the rapid determination of serum digitoxin levels. it differs from the original technique only in the sample volume being smaller and a digitoxin calibration curve being required. concurrent assays by a reference method (86rb-erythrocyte assay) gave results in excellent agreement with the values obtained by the modified elisa-technique on samples from patients und ... | 2000 | 111013 |
| [the role of tuberculin test and fluoroscopy in detecting intra- thoracic tuberculosis in children and adolescents living in the rural area with high incidence of tuberculosis]. | the analysis of 91 case records of children and adolescents living in rural area with a high incidence of tuberculosis was made. these patients were detected through screening and by means of tuberculin diagnosis and fluorography carried out by a team of health workers on a case-finding mission. the organization of work with due regard for the local conditions makes it possible to use the above methods for an early detection of the given disease; to assess the results obtained from the very begi ... | 2000 | 2150699 |
| [effects of hypertrophy on cardiac systolic and diastolic performance in athletes with mild hypertension]. | aims of the study has been the evaluation of morphological and functional aspects of left ventricle in subjects undergoing mild hypertension and sport adaptation effects. these evaluations have been carried out by echo-doppler both at rest and during sharp increase in after load induced by isometric stress. together with the morphological parameters represented by mass index and by radius to thickness ratio, we have studied stroke volume and transmitral flow pattern assessing the maximum flow ve ... | 2000 | 2150692 |
| [treatment of waldenström's macroglobulinaemia with high-doses cyclic corticosteroids (author's transl)]. | | 2000 | 111359 |
| [catheter infection in subclavian vein puncture]. | | 2000 | 101801 |
| [muscle blood flow and capillary diffusion capacity in patients with rheumatoid arthritis (author's transl)]. | capillary blood flow (xenon-133) and diffusion capacity for chrom-51-edta (ps-product of renkin) of striated muscle tissue were examined by double isotope method in patients with rheumatoid arthritis. xenon-clearance and ps-product were studied under normal conditions and following hyperemisation. there existed no significant difference between rheumatoid patients and normal subjects and there was no evidence of increased capillary permeability. apparently, derangement of muscle capillaries is r ... | 2000 | 101713 |
| superoxide dismutase as a regulatory switch in mammalian testicular steroidogenesis. | the delta 4-pathway of testosterone biosynthesis in leydig cells, widely believed to proceed through pregnenolone--greater than pregnenedione--greater than progesterone route catalyzed by 5 delta-3 beta-hydroxysteroid dehydrogenase and delta 5-delta 4-isomerase respectively is shown to pass through an alternate pathway mediated by superoxide dismutase and peroxidase. a built-in regulatory switch is incorporated in this route, with the superoxide dismutase inducible upon lh-stimulation of the ley ... | 2000 | 2175181 |
| perinatal perspective: introduction to this issue of the qrb. | | 2000 | 101945 |
| ["first" and "second" generation sulfonylureas: distinction or difference? (author's transl)]. | | 2000 | 98364 |
| [keratinizing and calcifying odontogenic cyst (author's transl)]. | | 2000 | 94605 |
| natural sesquiterpenoids. | | 2000 | 2193260 |
| oral rehabilitation by prosthetic restoration after maxillectomy for malignant tumors. | in maxillectomy patients, speech intelligibility between before and after insertion of prostheses has been reviewed by many investigators. speech intelligibility was not related to the size of the defect, but rather to the defect region. speech intelligibility was considerably improved by the use of prostheses. a great difference could not be found in escape rate from the nasal cavity between before and after insertion of prostheses, but there was a remarkable change in the spirometer. postmaxil ... | 2000 | 94595 |
| [pre- and postoperative erythrocyte volume distribution curves in children with cyanotic heart defects]. | the behaviour of the volume distribution curves (vvk) of red blood cells in children with cyanosed organic heart defect is reported by taking preoperative and postoperative observations as a basis. mcv determined from the volume distribution curve amounts to 80.3 micron3. if the volume distribution curves of the preoperative patient group are compared with the postoperative patient group (4 months) by means of the criteria dsmax, ds, inclination and dispersion, no significant changes can be iden ... | 2000 | 89988 |
| control of drug self-administration: the role of aversive consequences. | | 2000 | 101875 |
| [cost and time of medical care in an out-patient-clinic (author's transl)]. | | 2000 | 97650 |
| diabetic ketoacidosis. continuous infusion of low-dose insulin. | | 2000 | 97603 |
| local control and lethal toxicity in limited small cell lung cancer. | | 2000 | 2174843 |
| [clinical biochemical aspects of the prophylaxis and therapy of senile cataract with zinc aspartate (author's transl)]. | in the aetiology and pathogenesis of senile cataract a disturbed glucose utilisation is found. this reflects a loss of activity of some key enzymes for glycolysis in the lens. these enzymes (ald, g6pdh, hk, ldh, mdh and phosphofructokinase) are zinc metal enzymes. the decrease in activity of these enzymes can be compensated by the administration of specific cations. with zinc one can improve the impaired glucose metabolism occurring in old age. for the prophylaxis and therapy of senile cataract ... | 2000 | 97466 |
| [profile of a nurse: ms. makiko nemoto, a young nurse trained in a seventh day adventists' school]. | | 2000 | 97456 |
| [emergency care and nursing. 17. tetanus, gas gangrene, foreign bodies, drowning, and electrocution]. | | 2000 | 97454 |
| interactions between pairs of dna-specific fluorescent stains bound to mammalian cells. | the interactions between dna-specific fluorescence stains complexed with mitotic chinese hamster cells were studied by spectrofluorometric and flow fluorometric techniques. the degree of binding interactions and of energy transfer between stains was determined from the intensities and shapes of fluorescence emission spectra of cells complexed with pairs of stains. the stain pairs hoechst 33258-chromomycin a3, hoechst 33258-ethidium bromide, and chromomycin a3-ethidium bromide exhibited efficient ... | 2000 | 86583 |
| intrafamilial spread of hepatitis bs antigen. | | 2000 | 97419 |
| [severely increased alpha fetoprotein and associated diseases]. | in 1977 and 1978 the serum concentration of alpha-1-fetoprotein (afp) in 3200 patients was measured for diagnostic purposes. values above 320 ng/ml were observed in 75 patients; they underwent closer study. the final diagnoses were hepatoma (50), germ cell tumors (15), other malignant tumors (6) and acute hepatitis (4). also, chronic hepatitis and liver coma may be associated with afp values above 320 ng/ml. repeated measurements usually provide further diagnostic information. | 2000 | 92051 |
| [prognosis and long term survival of intracranial aneurysms operated under hypervolemic hypotension--natural history of 104 cases of intracranial aneurysms (author's transl)]. | | 2000 | 91990 |
| [pathology of brain trauma and its clinical evaluation (author's transl)]. | | 2000 | 91989 |
| determination of fetal sex by ultrasound. | | 2000 | 97313 |
| hyponatremia. | | 2000 | 97245 |
| an estimation of dental treatment needs in two groups of refugees in sweden. | the aim of this study was to estimate dental treatment need in groups of chilean and polish refugees in sweden. of the nordic countries, sweden accepts the greatest number of refugees. an average of 5000 refugees arrived annually in 1981-85, increasing to 15,000 during 1986-87. refugees and their families now comprise 93% of non-nordic immigration. in 1981-83 a sample of 193 chilean and 92 polish refugees in the county of stockholm was selected for this study. dental treatment needs were calcula ... | 2000 | 2195841 |
| [decrease in the mutagenic effect of thiophosphamide from the action of a xyethylidene diphosphonic acid derivative]. | | 2000 | 97173 |
| effect of gonadotropin-releasing hormone on depressed mood. | | 2000 | 91873 |
| [madame g.'s hyperthyroidism]. | | 2000 | 89684 |
| [pathogenesis of alzheimer's disease]. | the 160 and 200 kd phosphorylated and non-phosphorylated neurofilament monoclonal antibodies were used as the probe to study the cytoskeletal protein distribution inside cerebral neurons of 2 normal adults and 2 patients with alzheimer's disease (ad). immunocytochemical technique was applied in this study. non-phosphorylated neurofilament was located in the perikarua, whereas, the phosphorylated neurofilament was rich in the peripheral of the neuron's cell body and axons in the normal adult brai ... | 2000 | 2174279 |
| titanocene dichloride--the first metallocene with cancerostatic activity. | | 2000 | 111586 |
| [digestive reconstruction after proctocolectomy]. | | 2000 | 97145 |
| serum isoamylases in diseases of the lung and control subjects of thermolabile serum amylase component. | | 2000 | 94301 |
| thyrotoxicosis in a patient with secondary hypothyroidism. | we have described a patient with panhypopituitarism who developed thyrotoxicosis. there is a widespread belief that pituitary thyrotropin (tsh) is not a pathogenetic factor in most patients with thyrotoxicosis. due to technical reasons, however, it has been difficult to entirely exclude the role(s) of tsh in the development of thyrotoxicosis. in this report hyperthyroidism appeared in a patient with tsh deficiency proved by the lack of response to trh administration. this is the first known case ... | 2001 | 98848 |
| lowering blood-pressure. | | 2001 | 88583 |
| [experiences and results in the treatment of orl tumors with bleomycin and radiotherapy]. | | 2001 | 95493 |
| atrial septal thickness and area in normal heart specimens and in those with ostium secundum atrial septal defects. | this anatomic study suggests that an understanding of the thickness of the atrial septum should allow better visualization of most portions of the blade-shaped atrial septum during cross-sectional echocardiography, both in normal subjects and in patients with ostium secundum atrial septal defects. the thickness measurements also demonstrate that difficulties in imaging the atrial septum are a function of resolution limits of existing echocardiographic equipment. | 2001 | 114537 |
| magnetic susceptibility studies of laccase and oxyhemocyanin. | the magnetic susceptibility of rhus vernicifera laccase has been remeasured over the temperature range 5-260 k. in contrast to our previous results [solomon, e.i., dooley, d. m., wang r.-h., gray, h.b., cerdonio, m., mogno, f. & romani, g. l. (1975) j. am. chem. soc. 98, 1029-1031] linear chi versus t-1 behavior was observed. the susceptibility of limulus polyphemus oxyhemocyanin has also been measured in the range 5-260 k. only weak paramagnetism, attributable to dissolved oxygen and a small am ... | 2001 | 98765 |
| [indications for normovolemic hemodilution]. | so long as normovolaemic conditions are respected and the haematocrit is not reduced to less than 30 per cent, there are a large number of surgical and even medical indications for deliberate haemodilution. amongst the several contraindications, coronary insufficiency must be considered as being formal. | 2001 | 95460 |
| [therapeutic effects of pingyangmycin on malignant tumors (author's transl)]. | | 2001 | 95446 |
| testicular biopsy for infertility: a review of sixty-eight cases with a simplified histologic classification of lesions. | sixty-eight testicular biopsies (29 bilateral and 39 unilateral) done for evaluation of oligospermia and azoospermia are reviewed. a simplified classification of the histologic lesions observed is proposed. a brief discussion of the etiology and pathogenesis of some of these lesions is included. | 2001 | 88424 |
| the british columbia registry for handicapped children and adults: evolutionary changes over twenty years. | | 2001 | 125623 |