| characterization of the bacterial microbiota of biomphalaria glabrata (say, 1818) (mollusca: gastropoda) from brazil. | roughly 200 000 000 people in 74 countries infected with schistosomes all share the fact that they came in contact freshwater harbouring infected snails. the aim of the study is to characterize the microbiota of wild and laboratory-reared snails of biomphalaria glabrata from pernambuco, brazil. the microbiota of these molluscs was identified biochemically by the vitek 2 automated microbiological system. antimicrobial susceptibility testing was carried out by the disc diffusion method with ß-lact ... | 2013 | 23488866 |
| [preliminary analyses on bacterial diversity and resistance in infection-related skin disorders]. | to explore the bacterial diversity and resistance in infection-related skin disorders. | 2015 | 26704163 |
| in vitro antibacterial and antitumor activities of some medicinal plant extracts, growing in turkey. | to investigate antibacterial and antitumor activities of 51 different extracts prepared with 3 types of solvents (water, ethanol and methanol) of 16 different plant species (ajuga reptans (a. reptans) l., phlomis pungens (p. pungens) willd., marrubium astracanicum (m. astracanicum) jacq., nepeta nuda (n. nuda) l., stachys annua (s. annua) l., genista lydia (g. lydia) boiss., nuphar lutea (n. lutea) l., nymphaea alba (n. alba) l., vinca minor (v. minor) l., stellaria media (s. media) l., capsella ... | 2013 | 23790332 |
| growth and disinfestation of 6 different bacteria in embryogenic suspension cultures of cotton. | growth of 6 different common laboratory bacteria (escherichia coli, flavobacterium balustrum, xanthomonas maltophilia, enterobacter cloacae, pseudomonas fluorescens, and agrobacterium tumefaciens) in a bacterial medium, fresh plant medium, and "spent" plant media was initially measured. in all cases, bacteria grew best in the bacterial medium followed by the fresh plant medium. the spent plant medium did not support growth of the bacteria and apparently was actively toxic to bacterial cells. pro ... | 1991 | 24221727 |
| [screening probiotic endophytic bacteria from medicinal plant flex cornuta and the phytopathogen-inhibiting effect]. | culturable endophytic bacteria were isolated from medicinal plant ilex cornuta by plate-spreading method, strains with strong inhibitory effect on phytopathogen were screened by confrontation culture and fermentation filtrate culture methods, and the morphological changes of phytopathogen hyphae treated with endophytic bacteria were examined by microscopy and micrograph. their phylogenetic relationships were determined by homology analysis of the 16s rdna sequences of pcr products and the taxono ... | 2015 | 26571677 |
| antimicrobial activity of new 2-thioxo-benzo[g]quinazolin-4(3h)-one derivatives. | the antimicrobial activity of a synthesized series of 28 2-thioxo-benzo[g]quinazolin-4(3h)-one derivatives was evaluated in vitro against five gram-positive bacteria, including bacillus subtilis, enterococcus faecalis, staphylococcus aureus, staphylococcus epidermidis and streptococcus pyogenes. the antibacterial activity was extended to include five gram-negative bacteria: pseudomonas aeruginosa, escherichia coli, proteus mirabilis, klebsiella oxytoca and enterobacter cloacae. furthermore, the ... | 2016 | 27306606 |
| antimicrobial activity of synthesized 2-methylthiobenzo[g][1,2,4]- triazolo[1,5-a]quinazoline derivatives. | the present study was carried out to evaluate the antimicrobial activity of a synthesized 2-methylthio-benzo[g][1,2,4]triazolo[1,5- a]quinazoline series. the compounds (1-21) were tested against a variety of gram-positive bacterial species including bacillus subtilis (rcmb 01001 69-3), enterococcus faecalis (rcmb 0100154-2), staphylococcus aureus (rcmb 0100183-9), staphylococcus epidermidis (rcmb 0100183-9) and streptococcus pyogenes (rcmb 0100172-5). in addition, gram-negative bacteria were als ... | 2016 | 27140181 |
| [antiadhesive potencial of rhodococcus erythropolis imb ac-5017 biosurfactants]. | the effect of rhodococcus erythropolis imb ac-5017 biosurfactants (surface-active substances, sas) with different degree of purification on attachment of bacteria (escherichia coli iem-1, bacillus subtilis bt-2, proteus vulgaris bt-1, staphylococcus aureus bmc-1, pseudomonas aeruginosa p-55, enterobacter cloacae ac-22, erwinia aroidaeae b-433), yeasts (candida albicans d-6) and fungi (aspergillus niger p-3, fusarium culmorum t-7) to the abiotic surfaces (glass, plastic, ceramics, steel, linoleum ... | 2015 | 25639039 |
| analysis of microbial diversity in shenqu with different fermentation times by pcr-dgge. | shenqu is a fermented product that is widely used in traditional chinese medicine (tcm) to treat indigestion; however, the microbial strains in the fermentation process are still unknown. the aim of this study was to investigate microbial diversity in shenqu using different fermentation time periods. dgge (polymerase chain reaction-denaturing gradient gel electrophoresis) profiles indicated that a strain of pediococcus acidilactici (band 9) is the predominant bacteria during fermentation and tha ... | 2017 | 28256389 |
| biomineralization and formulation of endosulfan degrading bacterial and fungal consortiums. | microbial degradation offers an effective approach to remove toxicants and in this study, a microbial consortium consisting of bacterial strains and fungal strains were originally obtained from endosulfan contaminated agricultural soils. identification of the bacterial isolates by 16s rrna sequences revealed the isolates to be halophilic bacterium jas4, klebsiella pneumoniae jas8, enterobacter asburiae jas5, and enterobacter cloacae jas7, whereas the fungal isolates were identified by 18s rrna s ... | 2014 | 25454517 |
| antimicrobial activities of polyhexamethylene guanidine hydrochloride-based disinfectant against fungi isolated from cocoa beans and reference strains of bacteria. | this study was conducted to assess the antibacterial and the antifungal activity of a polyhexamethylene guanidine hydrochloride (phmgh)-based disinfectant and to determine if it could be used as a disinfectant for the treatment of cocoa beans. the activity of phmgh was tested in vitro for efficacy against five reference strains of pathogenic bacteria and six strains of fungi isolated from cocoa beans. all the strains tested were sensitive to the disinfectant. the mics reported were between 0.01 ... | 2012 | 22691490 |
| use of quantitative microbiological analyses to trace origin of contamination of parenteral nutrition solutions. | in the summer of 2010, parenteral nutrition (pn) admixtures were administered to neonates in the pediatric department of the university medical center mainz that provoked severe clinical sequelae. contamination of a dummy infusion with enterobacter cloacae and escherichia hermannii was detected on the day of the incident, and the same isolates were subsequently grown from all pn admixtures as well as from the parent amino acid solution from which the admixtures had been prepared. quantitative mi ... | 2012 | 22484833 |
| a bioinformatics approach to the determination of genes involved in endophytic behavior in burkholderia spp. | the vast majority of plants harbor endophytic bacteria that colonize a portion of the plant's interior tissues without harming the plant. like plant pathogens, endophytes gain entry into their plants hosts through various mechanisms. bacterial endophytes display a broad range of symbiotic interactions with their host plants. the molecular bases of these plant-endophyte interactions are currently not fully understood. in the present study, a set of genes possibly responsible for endophytic behavi ... | 2014 | 24513137 |
| the essential oil from the fruits of the brazilian spice xylopia sericea a. st.-hil. presents expressive in-vitro antibacterial and antioxidant activity. | the aims of this study were to investigate the chemical composition and the antioxidant activity and antibacterial activity of the essential oil of xylopia sericea fruits (oxs). the fruits of this species are popularly used for medicinal purposes, and as a condiment in food preparation. | 2017 | 28134988 |
| screening of mercury-resistant and indole-3-acetic acid producing bacterial-consortium for growth promotion of cicer arietinum l. | mercury resistant (hg(r) ) bacteria were screened from industrial effluents and effluents-polluted rhizosphere soils near to districts kasur and sheikhupura, pakistan. out of 60 isolates, three bacterial strains, bacillus sp. az-1, bacillus cereus az-2, and enterobacter cloacae az-3 showed hg-resistance as 20 μg ml(-1) of hgcl2 and indole-3-acetic acid (iaa) production as 8-38 μg ml(-1) . biochemical and molecular characterization of selected bacteria was confirmed by 16s ribotyping. mercury res ... | 2017 | 27911010 |
| bacteriocinogenic bacteria isolated from raw goat milk and goat cheese produced in the center of méxico. | currently, there are few reports on the isolation of microorganisms from goat milk and goat cheese that have antibacterial activity. in particular, there are no reports on the isolation of microorganisms with antibacterial activity from these products in central mexico. our objective was to isolate bacteria, from goat products, that synthesized antimicrobial peptides with activity against a variety of clinically significant bacteria. we isolated and identified lactobacillus rhamnosus, l. plantar ... | 2016 | 27407294 |
| antimicrobial and cytotoxic activities from jatropha dioica roots. | the antimicrobial and cytotoxic activities of organic extracts obtained from roots of the medicinal plant jatropha dioica (euphorbiaceae) were investigated. in order to evaluate their antimicrobial activity, the organic extracts were tested against clinical isolates of the human pathogens bacillus cereus, escherichia coli, salmonella typhi, staphylococcus aureus, enterobacter aerogenes, enterobacter cloacae, salmonella typhimurium, cryptococcus neoformans, candida albicans, candida parapsilosis ... | 2014 | 26031013 |
| antibacterial activity of ethyl acetate and aqueous extracts of mentha longifolia l. and hydroalcoholic extract of zataria multiflora boiss. plants against important human pathogens. | to determine the potential antibacterial activity of ethyl acetate and aqueous extracts from mentha longifolia l. (m. longifolia) and hydroalcoholic extract of zataria multiflora boiss. (z. multiflora) against important human pathogens. | 2014 | 25312118 |
| antimicrobial activity of ammodaucus leucotrichus fruit oil from algerian sahara. | three fruit oil samples of ammodaucus leucotrichus cosson & durieu from algerian sahara were obtained by hydrodistillation and analyzed by gc(ri), gc-ms and 13c nmr spectroscopy. the main compounds were perillaldehyde (87.0-87.9%) and limonene (7.4-8.2%). the antimicrobial effect of the essential oil was evaluated against bacteria, yeasts and filamentous fungi. high antibacterial activity was observed against escherichia coli, staphylococcus aureus. enterobacter cloaceae, bacillus cereus and sal ... | 2014 | 25026729 |
| identification of cultivable bacteria in the intestinal tract of bactrocera dorsalis from three different populations and determination of their attractive potential. | this study aimed to identify the cultivable bacteria inhabiting the intestinal tract of adult oriental fruit flies (bactrocera dorsalis) from laboratory-reared, laboratory sterile sugar-reared, and field-collected populations, and to evaluate the attractiveness of the metabolites produced by the above bacteria to their hosts. | 2014 | 23696217 |
| antimicrobial activity of schinus lentiscifolius (anacardiaceae). | schinus lentiscifolius marchand (syn. schinus weinmannifolius engl) is a plant native to rio grande do sul (southern brazil) and has been used in brazilian traditional medicine as antiseptic and antimicrobial for the treatment of many different health problems as well as to treat leucorrhea and to assist in ulcer and wound healing. although it is a plant widely used by the population, there are no studies proving this popular use. | 2013 | 23684720 |
| essential oil of mitracarpus frigidus as a potent source of bioactive compounds. | in our previous work (fabri et al. 2009), we showed that different extracts of mitracarpus frigidus had significant antibacterial, antifungal and leishmanicidal activities. in order to increase our knowledge about this species, this work assesses the chemical composition and the in vitro biological activity of its essential oil. thus, the essential oil obtained by hydrodistillation of the aerial parts of m. frigidus was analyzed by gc/ms. among several compounds detected, 11 were identified, bei ... | 2012 | 23207707 |
| chemical composition and antimicrobial activity of salvia x jamensis essential oil. | this is the first report about the composition of the essential oil of salvia x jamensis. the major compounds identified by gc-ms were beta-caryophyllene (14.8 %), beta-pinene (6.8 %), caryophyllene oxide (6.0 %), delta-cadinene (5.5 %), alpha-pinene (5.2 %) and spatulenol (5.2 %). the oil showed antimicrobial activity against three gram (+) bacteria: bacillus cereus, staphylococcus aureus, and s. epidermidis, and three candida strains: c. albicans, c. glabrata and c. tropicalis, while it was in ... | 2012 | 23074919 |
| antimicrobial activity of platelet (plt)-poor plasma, plt-rich plasma, plt gel, and solvent/detergent-treated plt lysate biomaterials against wound bacteria. | platelet (plt) gels exhibit antimicrobial activity useful for wound healing. the nature of the antibacterial component(s) is unknown. | 2013 | 22563709 |
| systematic metabolic engineering of escherichia coli for high-yield production of fuel bio-chemical 2,3-butanediol. | the production of biofuels by recombinant escherichia coli is restricted by the toxicity of the products. 2,3-butanediol (2,3-bd), a platform and fuel bio-chemical with low toxicity to microbes, could be a promising alternative for biofuel production. however, the yield and productivity of 2,3-bd produced by recombinant e. coli strains are not sufficient for industrial scale fermentation. in this work, the production of 2,3-bd by recombinant e. coli strains was optimized by applying a systematic ... | 2014 | 24525331 |
| nonrecovery of varying proportions of viable bacteria during spread plating governed by the extent of spreader usage and proposal for an alternate spotting-spreading approach to maximize the cfu. | to elucidate the cause of high variations and inconsistencies in bacterial cfu observed within and between different experiments while assessing viable bacterial counts through spread plating (sp). | 2012 | 22563785 |
| biological activities of morus celtidifolia leaf extracts. | the aims of this research were to examine the antibacterial, cytotoxic and antiradical/antioxidant activities of the organic extracts obtained from the leaves of the medicinal plant morus celtidifolia (family: moraceae). to evaluate its antimicrobial properties, m. celtidifolia was tested against the bacteria of medical importance: bacillus subtilis, staphyloccocus aureus, enterococcus faecalis, escherichia coli, enterobacter cloacae and enterobacter aerogenes. cytotoxic activity was assessed by ... | 2015 | 26142508 |
| applications of protein engineering to members of the old yellow enzyme family. | in the 20 years since massey's initial report in 1995, interest in using alkene reductases to prepare chiral intermediates for synthesis has grown rapidly. while native alkene reductases often show very high stereoselectivities toward favorable substrates, these enzymes have somewhat size-restricted active sites that limit their substrate ranges to small alkenes. in addition, most alkene reductases have the same stereoselectivities, which makes it difficult to access the "other" product enantiom ... | 2015 | 25940546 |
| rapid detection of bacteria in green tea using a novel pretreatment method in a bioluminescence assay. | tea is one of the most popular beverages consumed in the world, and green tea has become a popular beverage in western as well as asian countries. a novel pretreatment method for a commercial bioluminescence assay to detect bacteria in green tea was developed and evaluated in this study. pretreatment buffers with ph levels ranging from 6.0 to 9.0 were selected from mes (morpholineethanesulfonic acid), hepes (n-2-hydroxyethylpiperazine-n'-2-ethanesulfonic acid), or tricine buffers. to evaluate th ... | 2014 | 24853516 |
| metagenomic cloning and characterization of na⁺ transporters from huamachi salt lake in china. | moderately halophilic bacteria are a kind of extreme environment microorganism that can tolerate moderate salt concentrations ranging from 0.5m to 2.5m. here, via a metagenomic library screen, we identified four putative na(+) transporters, designated h7-nha, h16-mppe, h19-cap and h35-mrp, from moderately halophilic community in the hypersaline soil of huamachi salt lake, china. functional complementation observed in a na(+)(ca(2+))/h(+) antiporter-defective escherichia coli mutant (knabc) sugge ... | 2013 | 23218230 |
| bacillus subtilis and enterobacter cloacae endophytes from healthy theobroma cacao l. trees can systemically colonize seedlings and promote growth. | clonal genotypes resistant to fungal diseases are an important component of the cocoa production system in southeastern bahia state (brazil), so that technologies for faster production of stronger and healthier plantlets are highly desirable. in this study, the effects of inoculated bacterial endophytes isolated from healthy adult cacao plants on seedlings, and aspects related to inoculation methods, colonization patterns, and photosynthesis were investigated. sequencing of 16s rrna, hsp-60, and ... | 2013 | 23212670 |
| synergistic antibacterial activity of salvia officinalis and cichorium intybus extracts and antibiotics. | synergistic activity of salvia officinalis and cichorium intybus extracts and commonly used antibiotics, amoxicillin and chloramphenicol, were evaluated. interactions between plant extracts and antibiotics were tested by checkerboard method and interpreted as fic index. staphylococcus aureus atcc 25923, escherichia coli atcc 25922, pseudomonas aeruginosa atcc 27853 and clinical isolates staphylococcus aureus, bacillus subtilis, enterobacter cloacae, klebsiella pneumoniae, escherichia coli and pr ... | 2013 | 22594260 |
| minimum antimicrobial inhibitory concentration of carnosol and of the ethanol extract from lepichinia hastata (lamiaceae). | the minimum inhibitory concentrations (mic) of carnosol and of the ethanolic extract from the aerial part of lepechinia hastata were determined against streptococcus pyogenes, bacillus subtilis, staphylococcus aureus, s. epidermidis, s. aureus (2), s. aureus "a", and s. aureus "b", (strains "a" and "b" are resistant to penicillin and ampicillin), escherichia coli, enterobacter cloacae, klebsiella pneumoniae, salmonella typhimurium, proteus vulgaris, and pseudomonas aeruginosa and candida albican ... | 1998 | 23195903 |
| silver nanoparticles production by two soil isolated bacteria, bacillus thuringiensis and enterobacter cloacae, and assessment of their cytotoxicity and wound healing effect in rats. | production of silver nanoparticles by bacillus thuringiensis and enterobacter cloacae was performed and confirmed through uv-visible spectrophotometry, transmission electron microscopy (tem), and x-ray diffraction (xrd) analyses. the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay using mouse fibroblast cell line nih-3t3 d4 was carried out and ic50s of agnps were obtained. the nontoxic dose of each agnps solution was selected for wound healing assay. thirty-two rats were ... | 2016 | 27448276 |
| [bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents - special references to bacteria isolated between april 2011 and march 2012]. | bacteria isolated from surgical infections during the period from april 2011 to march 2012 were investigated in a multicenter study in japan, and the following results were obtained. in this series, 785 strains including 31 strains of candida spp. were isolated from 204 (78.8%) of 259 patients with surgical infections. five hundred and twenty three strains were isolated from primary infections, and 231 strains were isolated from surgical site infection. from primary infections, anaerobic gram-ne ... | 2014 | 25796741 |
| bacteriological examination of the abdominal effusion in bacterial peritonitis. | this study provides a contemporary epidemiology of aspirates taken during surgery from the abdominal cavity among patients with bacterial peritonitis to identify the isolates and study their sensitivity to antibiotics. our bacteriology investigations included isolation of poor cultures, and detection of microbes was conducted using a rapid identification system (api20e, api staph, api strep, api ana, biomerieux). rapid tests for detection of oxidase and catalase activity were also used. suscepti ... | 2016 | 27770528 |
| [bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between july 1982 and march 2012]. | this is an integrated summary of the results obtained from a 3-decade multicenter study on bacteria isolated from surgical infections in japan between july 1982 and march 2012. during the 3-decade study, 11,196 strains were isolated from 4,787 patients consisting of 2,132 patients with primary infection and 2,655 patients with surgical site infection. almost half of the primary infection was peritonitis, which accounted for 42.3%-55.5%. in contrast, most of the surgical site infection was wound ... | 2015 | 26349116 |
| in vitro fermentation of fructooligosaccharides with human gut bacteria. | fructooligosaccharides (fos) are one of the most studied prebiotics, selectively stimulating the growth of health-promoting bacteria in the host. however, there is increasing evidence that commensal gut bacteria, such as bacteroides fragilis, clostridium butyricum, enterobacter cloacae, and even the pathogenic escherichia coli ben2908, are also able to metabolize fos in vitro, and in some cases, fos displayed adverse effects. therefore, it is necessary to identify fos-metabolizing species that a ... | 2015 | 25653214 |
| [bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between april 2010 and march 2011]. | bacteria isolated from surgical infections during the period from april 2010 to march 2011 were investigated in a multicenter study in japan, and the following results were obtained. in this series, 631 strains including 25 strains of candida spp. were isolated from 170 (81.7%) of 208 patients with surgical infections. four hundred and twenty two strains were isolated from primary infections, and 184 strains were isolated from surgical site infection. from primary infections, anaerobic gram-nega ... | 2014 | 25549405 |
| intraoperative vancomycin use in spinal surgery: single institution experience and microbial trends. | retrospective case series. | 2014 | 24480966 |
| oem--a new medium for rapid isolation of onion-pathogenic and onion-associated bacteria. | onions (allium cepa l.) are plagued by a number of bacterial pathogens including pantoea ananatis, p. agglomerans, burkholderia cepacia, enterobacter cloacae, pectobacterium carotovorum subsp. carotovorum, xanthomonas axonopodis pv. axonopodis and several pseudomonas spp. we developed a semi-selective medium, termed onion extract medium (oem), to selectively and rapidly isolate bacteria pathogenic to and associated with onions and onion-related samples including bulbs, seeds, sets, transplant se ... | 2012 | 23041494 |
| biodegradation of s-triazine herbicide atrazine by enterobacter cloacae and burkholderia cepacia sp. from long-term treated sugarcane-cultivated soils in kenya. | in this study soils from sugarcane-cultivated fields were screened for bacterial species capable of atrazine (6-chloro-n²-ethyl-n⁴-isopropyl-1,3,5-triazine-2,4-diamine) degradation due to long exposure of the soils to this herbicide. to enrich for atrazine degraders, minimal salt medium containing atrazine as the sole n source and glucose as the c source was inoculated with soils impacted with this herbicide and incubated. bacterial growth was monitored by measuring optical density. the degradat ... | 2012 | 22575004 |
| peptidomics of acanthoscurria gomesiana spider venom reveals new toxins with potential antimicrobial activity. | acanthoscurria gomesiana is a brazilian spider from the theraphosidae family inhabiting regions of southeastern brazil. potent antimicrobial peptides as gomesin and acanthoscurrin have been discovered from the spider hemolymph in previous works. spider venoms are also recognized as sources of biologically active peptides, however the venom peptidome of a. gomesiana remained unexplored to date. in this work, a ms-based workflow was applied to the investigation of the spider venom peptidome. data- ... | 2017 | 27436114 |
| inhibitory effects of lactobacillus fermentum on microbial growth and biofilm formation. | beneficial effects of lactobacilli have been reported, and lactic bacteria are employed for conservation of foods. therefore, the effects of a lactobacillus fermentum strain were analyzed regarding inhibitory effects on staphylococci, candida albicans and enterotoxigenic enterobacteria by transmission electron microscopy (tem). tem of bacterial biofilms was performed using cocultures of bacteriocin-producing l. fermentum 97 with different enterotoxigenic strains: staphylococcus epidermidis expre ... | 2015 | 26267163 |
| [evaluation of mixed biofilm formation between candida albicans and a variety of bacterial species isolated from peripheral catheters at tlemcen chu. first study in algeria]. | mixed-species biofilms constitute a reservoir of infection for a group of bacteria and yeasts that coexist on the same support. peripheral venous catheters make up a good surface for the attachment of microorganisms that promote biofilm formation and this requires complex strategies for antimicrobial treatments. | 2015 | 25957712 |
| utilization of blood cultures in danish hospitals: a population-based descriptive analysis. | this national population-based study was conducted as part of the development of a national automated surveillance system for hospital-acquired bacteraemia and ascertains the utilization of blood cultures (bcs). a primary objective was to understand how local differences may affect interpretation of nationwide surveillance for bacteraemia. from the danish microbiology database, we retrieved all bcs taken between 2010 and 2013 and linked these to admission data from the national patient registry. ... | 2015 | 25658520 |
| [clinical and bacteriological characteristic of infectious purulent complications in patients after related renal transplantation]. | we investigated the frequency and characteristics of infectious purulent and non-infectious complications in living related renal transplant recipients in early postoperative period. it was identified the prevalent microorganisms in urinary tract infections and its antibiotic sensitivity: pseudomonas aeruginosa, escherichia coli, klebsiella pneumoniae, enterobacter cloacae, citrobacter freundii, staphylococcus epidermidis, enterococcus faecalis, candida albicans. 182 strains of bacteria and cand ... | 2014 | 25327674 |
| metabolic engineering of muconic acid production in saccharomyces cerevisiae. | the dicarboxylic acid muconic acid has garnered significant interest due to its potential use as a platform chemical for the production of several valuable consumer bio-plastics including nylon-6,6 and polyurethane (via an adipic acid intermediate) and polyethylene terephthalate (pet) (via a terephthalic acid intermediate). many process advantages (including lower ph levels) support the production of this molecule in yeast. here, we present the first heterologous production of muconic acid in th ... | 2013 | 23164574 |
| determination of antimicrobial activity and resistance to oxidation of moringa peregrina seed oil. | the antimicrobial activity of the oil extracted with n-hexane from the seeds of moringa peregrina was tested against staphylococcus aureus, s. epidermidis, pseudomonas aeruginosa, escherichia coli, enterobacter cloacae, klebsiella pneumoniae, candida albicans, c. tropicalis and c. glabrata. the oil proved effective against all of the tested microorganisms. standard antibiotics (netilmycin, 5-flucytocine, intraconazole and 7-amino-4-methylcoumarin-3-acetic acid) were used for comparison. the resi ... | 2012 | 22367027 |
| prevalence, antibiotic susceptibility and characterization of antibiotic resistant genes among carbapenem-resistant gram-negative bacilli and yeast in intestinal flora of cancer patients in north lebanon. | the emergence and spread of carbapenem-resistant bacteria are a significant clinical and public health concern. the aim of the study is to determine the prevalence of intestinal carriage of carbapenem-resistant bacteria and yeasts in cancer patients under chemotherapy. 41 stool samples collected from cancer patients in nini hospital in tripoli, north lebanon have been analyzed. after isolating yeasts and carbapenem-resistant bacteria, a biochemical identification and antimicrobial susceptibility ... | 2017 | 28216021 |
| infections from cvc in the pediatric neoplastic patient. single institution experience. | the present clinical study was carried out in order to evaluate in a perspective way the incidence of the infections caused by cvc, the micro-organisms mostly involved in the infectious process, the condition of aplasia in patients when blood cultures show positiveness and the incidence of removals expressed as number of performed removals/number of positive blood culture. | 2012 | 22728610 |
| capd peritonitis caused by co-infection with cellulosimicrobium cellulans (oerskovia xanthineolytica) and enterobacter cloacae: a case report and literature review. | a 50-year-old woman with end-stage renal disease on continuous ambulatory peritoneal dialysis was admitted with abdominal pain, fever and cloudy peritoneal fluid. the diagnosis was peritonitis, and the causative bacteria were cellulosimicrobium cellulans and enterobacter cloacae. she was subsequently treated with the administration of intraperitoneal antibiotics and removal of the infected indwelling catheter. we herein report a case of cellulosimicrobium cellulans and enterobacter cloacae co-in ... | 2015 | 25786454 |
| interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation. | guanylate-binding proteins (gbps) are essential components of cell-autonomous immunity. in response to ifn signaling, gbps are expressed in the cytoplasm of immune and nonimmune cells, where they unleash their antimicrobial activity toward intracellular bacteria, viruses, and parasites. recent studies have revealed that gbps are essential for mediating activation of the caspase-1 inflammasome in response to the gram-negative bacteria salmonella enterica serovar typhimurium, francisella novicida, ... | 2017 | 27418355 |
| microbiological diagnosis and antibiotic therapy in patients with community-acquired pneumonia and acute copd exacerbation in daily clinical practice: comparison to current guidelines. | the aim of this secondary analysis was to evaluate current microbiological approaches, microbiology, and antibiotic therapy in patients with community-acquired pneumonia (cap) and acute exacerbation of chronic obstructive pulmonary disease (aecopd) in clinical practice and to compare them with current international guidelines. | 2013 | 23564195 |
| neonatal bacterial conjunctivitis in korea in the 21st century. | to investigate the microbial cause and antibiotic susceptibility of neonatal bacterial conjunctivitis in korean patients in the 21st century. | 2017 | 28002109 |
| simplified and representative bacterial community of maize roots. | plant-associated microbes are important for the growth and health of their hosts. as a result of numerous prior studies, we know that host genotypes and abiotic factors influence the composition of plant microbiomes. however, the high complexity of these communities challenges detailed studies to define experimentally the mechanisms underlying the dynamics of community assembly and the beneficial effects of such microbiomes on plant hosts. in this work, from the distinctive microbiota assembled ... | 2017 | 28275097 |
| a single-day point-prevalence study of faecal carriers in long-term care hospitals in madrid (spain) depicts a complex clonal and polyclonal dissemination of carbapenemase-producing enterobacteriaceae. | the objective of this study was to describe the prevalence and microbiological characteristics of carbapenemase-producing enterobacteriaceae (cpe) colonizing patients in long-term care hospitals (ltchs) in madrid, spain. | 2016 | 26518051 |
| characterization of beta-lactamases in faecal enterobacteriaceae recovered from healthy humans in spain: focusing on ampc polymorphisms. | the intestinal tract is a huge reservoir of enterobacteriaceae, some of which are opportunist pathogens. several genera of these bacteria harbour intrinsic antibiotic resistance genes, such as ampc genes in species of citrobacter, enterobacter or escherichia genera. in this work, beta-lactamases and other resistance mechanisms have been characterized in enterobacteriaceae isolates recovered from healthy human faecal samples, focusing on the ampc beta-lactamase genes. fifty human faecal samples w ... | 2015 | 25501887 |
| analysis of bacterial diversity during the fermentation of inyu, a high-temperature fermented soy sauce, using nested pcr-denaturing gradient gel electrophoresis and the plate count method. | the diversity of bacteria associated with the fermentation of inyu, also known as black soy sauce, was studied through the nested pcr-denaturing gradient gel electrophoresis (dgge) of samples collected from the fermentation stages of the inyu production process. the dgge profiles targeted the bacterial 16s rdna and revealed the presence of citrobacter farmeri, enterobacter cloacae, enterobacter hormaechei, enterococcus faecium, klebsiella pneumoniae, pantoea agglomerans, salmonella enterica, ser ... | 2013 | 23200659 |
| sequencing and comparative genomics analysis of the inchi2 plasmids pt5282-mpha and p112298-cata and the inchi5 plasmid pynkp001-dfra. | incompatibility group inchi plasmids are important vectors of antibiotic resistance in enterobacteriaceae. in this study, a scheme for typing inchi into five separately clustering subgroups, including previously designated inchi1-3 as well as inchi4-5, was proposed based on sequenced inchi plasmids. the complete nucleotide sequences of the inchi2 plasmids pt5282-mpha and p112298-cata and the inchi5 plasmid pynkp001-dfra from clinical enterobacter cloacae, citrobacter freundii and raoultella orni ... | 2017 | 28390961 |
| multiregional dissemination of kpc-producing klebsiella pneumoniae st258/st512 genotypes in poland, 2010-14. | in 2008-09, the kpc carbapenemase epidemiology in poland was dominated by a klebsiella pneumoniae st258 kpc-2 outbreak in warsaw and its administrative region. the aim of this study was to analyse the situation in 2010-14, with a focus on new outbreaks in other parts of the country. | 2017 | 28333331 |
| global molecular epidemiology of imp-producing enterobacteriaceae. | international data on the molecular epidemiology of enterobacteriaceae with imp carbapenemases are lacking. we performed short-read (illumina) whole-genome sequencing on a global collection of 38 imp-producing clinical enterobacteriaceae (2008 to 2014). imp-producing enterobacteriaceae (7 varieties within 11 class 1 integrons) were mainly present in the south pacific and asia. specific blaimp-containing integrons (in809 with blaimp-4, in722 with blaimp-6, and in687 with blaimp-14) were circulati ... | 2017 | 28167555 |
| ndm-producing enterobacteriaceae in a chinese hospital, 2014-2015: identification of ndm-producing citrobacterwerkmanii and acquisition of blandm-1-carrying plasmid in vivo in a clinical escherichia coli isolate. | new delhi metallo-β-lactamase (ndm)-producing enterobacteriaceae (npe) shows prevalence in china. little is known about the mechanisms related to the spread of npe. recently, a total of 51 non-duplicated npe isolates were collected from a tertiary-care hospital in china and analysed for genetic relatedness by pfge, antimicrobial susceptibility by etest and sequence type by multilocus sequence typing. s1-pfge and southern blot analysis or pcr amplification were used for plasmid profiling. between ... | 2016 | 27667823 |
| incn st7 epidemic plasmid carrying blaimp-4 in enterobacteriaceae isolates with epidemiological links to multiple geographical areas in china. | to characterize blaimp-4-carrying plasmids originating from inpatients in hong kong. | 2017 | 27609049 |
| characterization of extended-spectrum β-lactamase (esbl)-producing klebsiella, enterobacter, and citrobacter obtained in environmental samples of a tunisian hospital. | the assessment of the hospital environment as a reservoir of esbl-producing enterobacteriaceae in tunisian hospitals is scarcely analyzed, except for escherichia coli. the aim of this study was to evaluate the presence of esbl-producing non-e. coli enterobacteriaceae (esbl-ebnoec) in 300 samples of abiotic surfaces and the hands of patients and staff of a tunisian hospital, and to characterize the esbl genes of the recovered isolates. esbl-ebnoec were recovered in 28 of 300 (9.3%) analyzed sampl ... | 2016 | 27492133 |
| risk of infection transmission in curvilinear array echoendoscopes: results of a prospective reprocessing and culture registry. | the complex design of the elevator mechanism in duodenoscopes has been recognized as a challenge for disinfection and recently implicated as a potential source of persistent bacterial contamination. curvilinear array (cla) echoendoscopes also have an elevator mechanism; however, there are no recommendations or data regarding the risk of persistent bacterial contamination of echoendoscopes. here we hoped to determine the yield of microbial growth with routine bacterial surveillance cultures of re ... | 2017 | 27478029 |
| antimicrobial resistance patterns of enterobacteriaceae in european wild bird species admitted in a wildlife rescue centre. | wild birds have been considered to be reservoirs of enteric human pathogens and vectors of resistance dissemination to the environment. during annual migration, they potentially play a role in the epidemiology of human associated zoonoses. the aim of this study was to investigate the frequency of isolation and antimicrobial susceptibility profiles of enterobacteriaceae members isolated from cloacal swabs of common european wild birds. fifty-five cloacal swabs were taken during birds' entrance ev ... | 2016 | 27393875 |
| multidrug-resistant enterobacteriaceae from indoor air of an urban wastewater treatment plant. | wastewater treatment plants (wwtps) have been recognized as sources of bioaerosols that may act as vehicles for dissemination of pathogens and multidrug-resistant (mdr) bacteria. the occurrence of mdr enterobacteriaceae in indoor air of an urban wwtp was investigated. a possible airborne contamination with extended-spectrum beta-lactamase (esbl) and carbapenemase-producing enterobacteriaceae was also explored. fourteen of 39 enterobacteriaceae isolates were mdr. these isolates were found at all ... | 2016 | 27260528 |
| molecular characterization of class b carbapenemases in advanced stage of dissemination and emergence of class d carbapenemases in enterobacteriaceae from croatia. | carbapenemases involved in acquired carbapenem resistance in enterobacteriaceae belong to ambler class a serin β-lactamases, class b metallo-β-lactamases (mbl) or class d oxa-48-like β-lactamases. the aim of the present study was to analyse the molecular epidemiology and the mechanisms and routes of spread of class b and class d carbapenemases in croatia. in total 68 isolates were analyzed. antibiotic susceptibility was determined by broth microdilution method. pcr was used to detect antibiotic- ... | 2016 | 27174090 |
| mobilization of the salmonella genomic island sgi1 and the proteus genomic island pgi1 by the a/c2 plasmid carrying blatem-24 harboured by various clinical species of enterobacteriaceae. | the objective of this study was to transfer the salmonella genomic islands (gis) sgi1 and sgi1-v and the proteus gi pgi1-pmesc to clinical isolates of enterobacteriaceae harbouring an a/c2 plasmid. | 2016 | 27150396 |
| carbapenemase-producing enterobacteriaceae in hospital wastewater: a reservoir that may be unrelated to clinical isolates. | carbapenemase-producing enterobacteriaceae (cpe) are an emerging infection control problem in hospitals worldwide. identifying carriers may help reduce potential spread and infections. | 2016 | 27107615 |
| mechanisms of ertapenem resistance in enterobacteriaceae isolates in a tertiary university hospital. | the aim of this study was to investigate the molecular mechanisms of ertapenem resistance among enterobacteriaceae isolates in a clinical microbiology laboratory at a tertiary university hospital. a total of 40 clinical isolates including 20 resistant and 20 intermediate isolates were collected from august 2012 to july 2013. ertapenem susceptibility was confirmed by the broth microdilution method. pcr and sequencing analysis of carbapenemase, ampc β-lactamase, and extended-spectrum β-lactamase ( ... | 2016 | 27101841 |
| dissemination of the blakpc gene by clonal spread and horizontal gene transfer: comparative study of incidence and molecular mechanisms. | in addition to the global spread of the kpc-producing klebsiella pneumoniae (kpc-kp) clonal complex (cc)-258 clone, the blakpc gene may also spread by horizontal gene transfer (hgt), as suspected when more than one kpc-producing enterobacteriaceae (kpc-ent) species are isolated in a single patient. we aimed to characterize the incidence and molecular features of kpc-kp that were isolated alone (singular kpc-kp) versus kpc-kp that were isolated together with another kpc-ent species (joint kpc-kp) ... | 2016 | 27073266 |
| cesarean section changes neonatal gut colonization. | delivery by means of cesarean section has been associated with increased risk of childhood immune-mediated diseases, suggesting a role of early bacterial colonization patterns for immune maturation. | 2016 | 27045582 |
| in vivo horizontal dissemination of the blakpc-2 gene carried on diverse genetic platforms among clinical isolates of enterobacteriaceae. | this study investigated the molecular characteristics of six blakpc-positive enterobacteriaceae recovered from three patients in argentina. antimicrobial susceptibility testing was performed following clinical and laboratory standards institute (clsi) 2014 recommendations. molecular characterisation of the isolates was performed by biparental conjugation, pcr, sequencing, s1 nuclease restriction, and southern blot hybridisation with a blakpc probe using standard protocols and conditions. the iso ... | 2015 | 27873711 |
| acute cholecystitis associated with infection of enterobacteriaceae from gut microbiota. | acute cholecystitis (ac) is one of the most common surgical diseases. bacterial infection accounts for 50% to 85% of the disease's onset. since there is a close relationship between the biliary system and the gut, the aims of this study were to characterize and determine the influence of gut microbiota on ac, to detect the pathogenic microorganism in the biliary system, and to explore the relationship between the gut and bile microbiota of patients with ac. a total of 185 713 high-quality sequen ... | 2015 | 26025761 |
| antibacterial susceptibility of enterobacteriaceae isolated from raw horsemeat isolated for human consumption (basashi). | drug susceptibility testing was carried out using 14 antibiotics in order to identify trends in the antibiotic tolerance of 142 strains of enterobacteriaceae isolated from horsemeat commercially available for raw consumption (basashi). a comparison of the sensitivity to the 14 antibiotics using the 90% mic (minimum inhibitory concentration) values (mic90) showed the strongest tolerance to ampicillin (abpc) at a concentration of > 128 μg/ml, followed by that to fosfomycin (fom) at a concentration ... | 2015 | 25817809 |
| in vitro activity of fosfomycin tromethamine against extended spectrum beta-lactamase producing urinary tract bacteria. | to determine the in vitro activity of fosfomycin tromethamine against extended spectrum beta-lactamase producing uropathogens. | 2014 | 25523727 |
| incidence of fecal enterobacteriaceae producing broad-spectrum beta-lactamases in patients with hematological malignancies. | given the steadily increasing numbers of resistant bacteria, the frequency and severity of infections are on the rise. in patients with hematological malignancies, the treatment itself increases the risk of complicating bacterial infections. one important mechanisms of resistance is production of broad-spectrum beta-lactamases, increasingly detected not only in bacterial pathogens but also in bacteria contained in the normal microflora of the human body. the objectives of this study were determi ... | 2015 | 25270106 |
| ndm-1-producing enterobacteriaceae from south africa: moving towards endemicity? | we describe 4 patients infected with ndm-1 enterobacter cloacae, citrobacter freundii, and serratia marcescens from south africa that co-produced shv-12, ctx-m-3, and ctx-m-15 and were positive for qnrs, qnra, aac(6')-ib-cr, rmtf, rmtc, and arma. plasmids belonged to incn, inca/c replicon types with ccdab and vagc/d addiction factors. local and imported cases of ndm-producing bacteria co-exist within south africa. | 2014 | 24853768 |
| in vitro susceptibility and distribution of beta-lactamases in enterobacteriaceae causing intra-abdominal infections in north america 2010-2011. | the study for monitoring antimicrobial resistance trends has been monitoring the activity of antimicrobials indicated for the treatment of intra-abdominal infections since 2004. this report documents the in vitro activity of several recommended antimicrobials against 3449 gram-negative bacilli isolated from the 30 and 25 participating sites in north america in 2010-2011, respectively, and characterizes the extended-spectrum beta-lactamases (esbl) identified in esbl-positive and ertapenem-non-sus ... | 2014 | 24813688 |
| [the genotype and epidemiological feature of the enterobacteriaceae carrying carbapenemase in china]. | to analyze the genotype and molecular epidemiology of carbapenem-resistant enterobacteriaceae. | 2014 | 24767163 |
| [comparison of routine use of two chromogenic media chromid cps (biomérieux) and uriselect4 (bio-rad) for the detection of escherichia coli and major uropathogenics in urine]. | escherichia coli is the most common bacterial cause of urinary tract infections. its rapid and specific identification in urine samples represents a major challenge within the rendering results and optimizing the management of the patient. we aimed to compare the sensitivity and specificity of two commercially available chromogenic media for e. coli: chromid cps (biomérieux) and uriselect4 (bio(-)rad), without carrying out further tests. 99 consecutive and non-redundant urine samples considered ... | 2014 | 24736143 |
| diversity of carbapenemases in clinical isolates of enterobacteriaceae in croatia--the results of a multicentre study. | since the first carbapenem-resistant klebsiella pneumoniae strain was isolated in 2008, enterobacteriaceae with reduced susceptibility to one or more carbapenems have emerged sporadically in different geographical regions in croatia. these observations gave rise to a multicenter study on carbapenem resistance in enterobacteriaceae from croatia. fifty-seven carbapenem-non-susceptible strains of enterobacteriaceae were collected during 2011-2012 from four large hospital centres in croatia. overall ... | 2014 | 24674100 |
| new hydrazines with sulphonamidic structure: synthesis,characterization and biological activity. | infections caused by bacterial species are common in immunocompromised patients and carry significant treatment costs and mortality. the emerging resistance of microorganisms to some synthetic antimicrobial agents makes it necessary to continue the research for new antimicrobial drugs. | 2016 | 24505922 |
| characterization of kpc-2-producing escherichia coli, citrobacter freundii, enterobacter cloacae, enterobacter aerogenes, and klebsiella oxytoca isolates from a chinese hospital. | twelve nonduplicated kpc-2-producing enterobacterial isolates, including three escherichia coli, two citrobacter freundii, two enterobacter cloacae, four enterobacter aerogenes, and one klebsiella oxytoca, were collected from various clinical samples within 18 months (march 2011 to september 2012). two of the 12 patients died from infections caused by kpc-2-producing pathogens, while the rest of the patients with kpc-2-producing pathogens improved or were cured. the majority of the clinical isol ... | 2014 | 24433026 |
| [dissemination of blaimp-8 among enterobacteriaceae isolates from a buenos aires hospital]. | from august 2008 to december 2011, six metallo-β-lactamase-producing isolates, four enterobacter cloacae, one klebsiella oxytoca and one citrobacter freundii, were detected at hospital interzonal general de agudos "evita" in lanús. all six isolates showed multiresistant profiles and the presence of the blaimp-8 gene. five isolates also expressed per-2 extended spectrum β-lactamase. the blaimp-8 gene was found as the first cassette in a class 1 integron. however, the 3´ conserved sequence could n ... | 2013 | 23876273 |
| synthesis and biological evaluation of new 2-azetidinones with sulfonamide structures. | new series of n-(arylidene)hydrazinoacetyl sulfonamides 4a1-6, 4b1-6 and n-(4-aryl-3-chloro-2-oxoazetidin-1-yl)aminoacetyl sulfonamides 5a1-6, 5b1-6 were synthesized. the structures of the new derivatives was confirmed using spectral methods (ft-ir, 1h-nmr, 13c-nmr). the antibacterial activities of these compounds against gram positive (staphylococcus aureus atcc 6583, staphylococcus epidermidis atcc 12228, enterococcus faecalis atcc 25912) and gram negative (klebsiella pneumoniae cip 53153, pro ... | 2013 | 23567362 |
| serum in vivo and in vitro activity of single dose of ertapenem in surgical obese patients for prevention of ssis. | despite progress made in the control of post-operative infections, the incidence of surgical site infections (ssis) is still high. an improper perioperative antibiotic use can expose patients to the risk of resistant microorganisms, and, in surgical obese patients, the drug dosage and infusion time are critical points. the aim of our study was to evaluate the effectiveness of ertapenem in the prophylaxis of ssis in obese patients undergoing general or bariatric surgery. | 2013 | 23504617 |
| identification of the enterobacteriaceae in montasio cheese and assessment of their amino acid decarboxylase activity. | the aim of the study was to identify the species of enterobacteriaceae present in montasio cheese and to assess their potential to produce biogenic amines. plate count methods and an enterobacterial repetitive intergenic consensus polymerase chain reaction (eric-pcr) approach, combined with 16s rdna sequencing, were used to investigate the enterobacteriaceae community present during the cheesemaking and ripening of 6 batches of montasio cheese. additionally, the potential decarboxylation abiliti ... | 2013 | 23298547 |
| intestinal enterobacteriaceae and escherichia coli populations in japanese adults demonstrated by the reverse transcription-quantitative pcr and the clone library analyses. | a primer set specific for escherichia coli/shigella 16s rrna was developed and used for rt-qpcr analysis of fecal samples from 35 healthy adult volunteers in combination with the previously reported primer set specific for enterobacteriaceae. enterobacteriaceae and e. coli were present in the 29 out of 35 volunteers tested as intestinal commensals at the average population levels of 10(7.1±0.9) and 10(6.8±0.7)cellsg(-1) of stools (mean±standard deviation), respectively. among the 7 volunteers, t ... | 2013 | 23262033 |
| characterization of aminoglycoside-modifying enzymes in enterobacteriaceae clinical strains and characterization of the plasmids implicated in their diffusion. | a total of 788 clinical enterobacteriaceae were collected to describe the aminoglycoside-modifying genes (ame genes) and to characterize the plasmids that carry these genes. among the 788 strains collected, 330 (41.8%) were aminoglycoside-resistant: 264 escherichia coli (80%), 33 proteus mirabilis (10%), 10 klebsiella pneumoniae (3%), six k. oxytoca (1.8%), five enterobacter cloacae (1.5%), three morganella morganii (0.9%), three providencia stuartii (0.9%), two salmonella enterica (0.6%), and o ... | 2013 | 23206280 |
| dissemination of incfii(k)-type plasmids in multiresistant ctx-m-15-producing enterobacteriaceae isolates from children in hospital paediatric oncology wards. | in this study, extended-spectrum β-lactamase (esbl)-producing enterobacteriaceae isolates in children with malignancies hospitalised at a paediatric oncology department in the czech republic were investigated. from june 2009 to january 2010, a total of 50 esbl-producing faecal isolates of enterobacteriaceae were obtained from 28 patients. these isolates were characterised with regard to esbl enzymes, plasmid-mediated quinolone resistance genes, multilocus sequence typing (mlst) and plasmids conf ... | 2012 | 23043911 |
| bloodstream infections caused by imp-8-producing enterobacteriaceae isolates: the need for clinical laboratory detection of metallo-β-lactamases? | a retrospective study was conducted at a taiwanese medical center to characterize bloodstream infections caused by imp-8 metallo-β-lactamase (mbl)-producing enterobacteriaceae isolates and to assess the need for laboratory detection of imp producers. we analyzed 37 patients infected with imp-8 producers (two escherichia coli, nine klebsiella pneumoniae, 25 enterobacter cloacae, and one citrobacter freundii) and 107 patients infected with non-imp-8 producers (eight e. coli, 26 k. pneumoniae, 70 e ... | 2013 | 23001510 |
| [investigation of plasmid-mediated quinolone resistance determinants in enterobacteriaceae: a multicenter study]. | fluoroquinolones which are in use since 1986, are effective agents both against gram-positive and gram-negative bacteria. quinolones show bactericidal effect as a result of inhibition of dna gyrase and topoisomerase iv enzymes. main quinolone resistance mechanisms are chromosomal mutations in these enzymes and decreased intracellular accumulation due to efflux pumps or decreased membrane uptake. recently a new quinolone resistance mechanism mediated by plasmids has been defined. these plasmids c ... | 2012 | 22951649 |
| detection of amp c genes encoding for beta-lactamases in escherichia coli and klebsiella pneumoniae. | amp c beta-lactamase are ambler class c enzymes that confer resistance to extended spectrum cephalosporins and are not inhibited by beta-lactamase inhibitors. their detection is crucial, since the phenotypic tests are not standardised leading to ambiguity in interpretation of results. this study was done to detect the types of amp c prevalent in escherichia coli and klebsiella pneumoniae by multiplex polymerase chain reaction (pcr). | 2014 | 22885194 |
| characterization of the modified hodge test-positive isolates of enterobacteriaceae in taiwan. | the modified hodge test is a phenotypic test to detect kpc-type carbapenemase producers among enterobacteriaceae, as recommended by the clinical laboratory standards institute. however, false positive results were reported. in this study, we aimed to large-scale investigate the characterization of the modified hodge test-positive isolates of enterobacteriaceae collected between 2006 and 2010 in taiwan. | 2013 | 22578642 |
| enterobacteriaceae producing the kpc-2 carbapenemase from hospital sewage. | fifteen isolates with reduced susceptibility to meropenem were obtained from hospital sewage. they contained bla(kpc-2) and belonged to multiple clones of citrobacter freundii or enterobacter cloacae. bla(kpc-2) was commonly carried by self-transmissible plasmids with different ecori-restricted patterns. tn2 was identified upstream of bla(kpc-2), while iskpn6 lay downstream. hospital sewage could be an important reservoir of bla(kpc-2) and warrants more studies. | 2012 | 22463869 |
| in vitro susceptibilities of clinical isolates of ertapenem-non-susceptible enterobacteriaceae to cefotaxime, ceftazidime, cefepime and aztreonam. | to investigate the in vitro susceptibility of ertapenem-non-susceptible enterobacteriaceae (ense) isolates to cefotaxime, ceftazidime, cefepime and aztreonam. | 2012 | 22345386 |
| supporting the ceftaroline fosamil/avibactam enterobacteriaceae breakpoint determination using humanised in vivo exposures in a thigh model. | previous in vivo studies using a human-simulated regimen of ceftaroline/avibactam 600/600mg every 8h (q8h) showed activity against extended-spectrum β-lactamase-, ampc- and kpc-producing enterobacteriaceae with minimum inhibitory concentrations (mics) ≤ 1 μg/ml. here we sought to determine the efficacy of this human-simulated regimen against organisms with mics ≥ 1 μg/ml to help determine a breakpoint value that would reliability predict efficacy in humans. in total, 31 isolates (1 escherichia c ... | 2014 | 25278330 |