| diagnosis of biofilm infections in cystic fibrosis patients. | chronic pseudomonas aeruginosa biofilm lung infection in cystic fibrosis patients is the best described biofilm infection in medicine. the initial focus can be the paranasal sinuses and then follows repeated colonization and infection of the lungs by aspiration. the matrix of the biofilms is dominated by alginate and the pathogenesis of tissue damage is immune complex-mediated chronic inflammation dominated by polymorphonuclear leukocytes and their products (dna, oxygen radicals and proteases). ... | 2017 | 28407432 |