| chromosomal homology and divergence between sibling species of deer mice: peromyscus maniculatus and p. melanotis (rodentia, cricetidae). | | 1978 | 28563738 |
| genetic regulation of liver alcohol dehydrogenase in peromyscus. | data from genetic crosses of peromyscus maniculatus and p. polionotus suggests that electrophoretic variants of liver alcohol dehydrogenase are coded by alleles at a single locus. these alleles, designated adhf, adhs, and adhn, determine, respectively, the fast, slow, and not detectable (null) adh electrophoretic phenotype. heterozygotes (adhf/adhs) exhibit three bands on zymograms, suggesting a dimeric subunit structure for the enzyme. however, adhf/adhn and adhs/adhn animals exhibit a single b ... | 1978 | 736881 |
| seasonally variable effects of conspecific odors upon capture of deer mice (peromyscus maniculatus gambelii). | | 1978 | 678266 |
| preferences by deer mice for solutions of sugars, salts, and acids in richter-type drinking tests. | deer mice (peromyscus maniculatus) were tested for taste preferences in 48-hour, richter-type drinking tests (sapid solution versus distilled water). the ss, which were seven male and seven female wild adults, were individually housed within an environmental chamber. test solutions were concentrations of five sugars and three salts (.005 m to 1.0 m) and of two acids (4.0 ph to 1.5 ph). the molar range was too limited to identify the most preferred concentration of glucose, but peak preferences f ... | 1978 | 26730 |
| dispersal of deer mice, peromyscus maniculatus : proximal causes and effects on fitness. | dispersal of deer mice, peromyscus maniculatus, was measured as immigration to and emigration from two control areas, and as immigration to a removal area. the number of mice dispersing was linearly related to the densities on the control areas, while the proportion of the population dispersing (rate of dispersal) was correlated primarily with the rate of increase of control populations. high rates of dispersal were also associated with a breakdown of the established social structure in the spri ... | 1978 | 28309396 |
| vulnerability of bot fly (cuterebra) infected peromyscus maniculatus to shorttail weasel predation in the laboratory. | in the laboratory, peromyscus bearing a single cuterebra larva are no more vulnerable to weasel predation than are uninfected control mice, and may be taken less often under certain conditions. mice bearing two or more larvae appear to be more vulnerable than either controls or singly infected mice. their increased vulnerability probably results from their failure to use arboreal pathways. decreased activity may be responsible for the relative advantage of singly infected mice. previous reports ... | 1978 | 633515 |
| effects of bot fly (cuterebra) parasitism on activity patterns of peromyscus maniculatus in the laboratory. | peromyscus maniculatus subjected to bot fly (cuterebra) parasitism in the laboratory showed significant changes in amount and temporal distribution of several activity patterns. strenuous activities, such as running in an exercise wheel or stereotypic somersaulting, declined while less strenuous activities associated with maintenance behaviors increased. diurnal response to handling and disturbance declined significantly in infected mice. the temporal distribution of nocturnal activity was alter ... | 1978 | 564978 |
| the natural history and development of cuterebra approximate (diptera: cuterebridae) in its natural host, peromyscus maniculatus (rodentia: cricetidae), in western montana. | | 1977 | 606811 |
| effects of experimental bot fly parasitism on gonad weights of peromyscus maniculatus. | | 1977 | 925527 |
| space utilization of peromyscus: social and spatial factors. | space utilization of peromyscus maniculatus bairdi and p. leucopus noveboracensis was studied in laboratory enclosures. after 1 week, individuals were given access to twice as much space for an additional week. the new rea was either vacant or was occupied by a similarly experienced conspecific of the same or opposite sex. patterns of space utilization and reaction to the doubling of space were species specific. each species displayed specific patterns of social behaviour and only p. maniculatus ... | 1977 | 560813 |
| serum corticosterone concentrations in reproductively mature and inhibited deermice (peromyscus maniculatus bairdii). | serum corticosterone concentrations were measured to see if there was any correlation between adrenal activity and reproductive inhibition. males and females from two growing and one stable (asymptotic) population had significantly smaller reproductive organs (seminal vesicles, testes, uteri, ovaries) than controls. the weights of the adrenal glands of population mice were smaller, often significantly so, than those of controls, but the mean serum corticosterone concentrations were higher than t ... | 1977 | 850211 |
| genetic divergence of insular populations of deer mice. | electrophoretic variants at 28 genetic loci were analyzed in subspecies of peromyscus maniculatus endemic to the channel islands of the california coast. the genetic variability within insular populations was calculated. these deer mice have relatively high levels of polymorphism for insular populations. the mean heterozygosity per individual varies in the populations, being much higher on one of the islands than the others. nei's measure of genetic distance between groups compared on the basis ... | 1976 | 1008806 |
| genetic and developmental variation of hemoglobin in the deermouse, peromyscus maniculatus. | a genetic investigation of electrophoretic hemoglobin variants of the deermouse, peromyscus maniculatus, shows three alleles, hblf, hblr, and hblo, at a duplicated site controlling the six adult phenotypes. the hblf allele has not been described previously. the hemoglobin locus is not closely linked to the albino locus. fetal hemoglobin is distinct from any of the adult components and has a slower electrophoretic mobility. the fetal phenotype changes to the adult type between the days 15 and 18 ... | 1976 | 962849 |
| reproductive performance of a laboratory colony of the deermouse, peromyscus maniculatus gambelii. | during a 23-mo period approximately 600 litters and 2,500 offspring were produced in a laboratory colony established with wild-trapped deermice (peromyscus maniculatus gambelii). the incidence of pregnancy and size of litters increased with domestication. average litter size was 4.3 for all litters and 4.1 and 4.7 for litters born to wild-trapped and first generation females, respectively. litter size increased up to the seventh sequential pregnancy for both wild-caught and first-generation fema ... | 1975 | 1152419 |
| physiological consequences of experimentally altering the population structure of peromyscus maniculatus in the field. | | 1975 | 237700 |
| the effects of differential prenatal and postnatal social enviroments on sexual maturation of young prairie deermice (peromyscus maniculatus bairdii). | we compared the influence of different social enviroments on sexual maturation of young prairie deermice. between 12 and 48 hr after parturition, one-half of a litter from a population was exchanged with one-half of a litter from a bisexual pair. in each situation the remaining half-litter served as controls for the exchange procedure. the testes and vesicular weights of population-reared males were significantly larger than those of males reared by bisexual pairs, irrespective of prenatal envir ... | 1975 | 1163849 |
| plasma progesterone concentrations in prairie deermice (peromyscus maniculatus bairdii) from experimental laboratory populations. | body weights, ovary weights, plasma progesterone concentrations and ovarian histology were studied in females from asymptotic laboratory populations in which reproduction was inhibited and throughout the oestrous cycle of control nulliparous prairie deermice. body and ovary weights of population animals were significantly lighter and plasma progesterone concentrations were not significantly different from those of the control females. the control females exhibited cyclic changes in plasma proges ... | 1975 | 1123810 |
| peromyscus: effect of early pairing on reproduction. | sibling mating in prairie deer mice (peromyscus maniculatus bairdi) results in poor reproductive performance. siblings experimentally paired before puberty exhibit delayed reproduction when adult. a behavioral mechanism is involved in this reproductive delay, since prepubertal familiarity also delays reproduction in nonsibling pairs. such a reproductive delay may act to reduce inbreeding depression and regulate population growth. | 1974 | 4469697 |
| genetic compatibility of peromyscus maniculatus and peromyscus melanotis, as indicated by breeding studies and morphometrics. | | 1974 | 4443646 |
| artificial insemination of deermice (peromyscus maniculatus) with sperm from other rodent species. | | 1974 | 4448940 |
| control of plague vectors on peromyscus maniculatus by use of 2 percent carbaryl dust in bait stations. | | 1974 | 4208145 |
| immunity to hymenolepis citelli by peromyscus maniculatus: genetic control and ecological implications. | | 1974 | 4814797 |
| intake and requirements of energy and protein for the breeding of wild deermice, peromyscus maniculatus. | | 1973 | 4522377 |
| chromosomal, electrophoretic, and breeding studies of selected populations of deer mice (peromyscus maniculatus) and black-eared mice (p. melanotis). | | 1973 | 28564927 |
| recovery of reproductive function by prairie deermice (peromyscus maniculatus bairdii) from asymptotic populations. | | 1973 | 4748748 |
| occurrence of successful multiple insemination of females in natural populations of deer mice (peromyscus maniculatus). | | 1973 | 28563668 |
| host resistance in a natural host-parasite system. resistance to hymenolepis citelli by peromyscus maniculatus. | | 1973 | 4687483 |
| behavioral consequences of crowding in the deermouse (peromyscus maniculatus). | | 1972 | 5066262 |
| a comparative and developmental analysis of the midventral sebaceous glands in 18 taxa of peromyscus, with an examination of gonadal steroid influences in peromyscus maniculatus bairdii. | | 1972 | 5016688 |
| growth in two subspecies of peromyscus maniculatus. | | 1972 | 5016684 |
| novelty-induced self-food deprivation in wild and semi-domestic deermice (peromyscus maniculatus bairdii). | | 1972 | 5058880 |
| chromosomes of peromyscus (rodentia, cricetidae). 3. polymorphism in peromyscus maniculatus. | | 1972 | 4119112 |
| postnatal development in peromyscus maniculatus-polionotus hybrids. ii. tail and hind foot growth. | | 1971 | 5143701 |
| hormonal regulation of srna methylase activity in regional brain areas in peromyscus maniculatus bairdii. | | 1971 | 5113522 |
| correlations between physiological parameters of blood and altitude in peromyscus maniculatus. | | 1971 | 5581378 |
| some developmental observations on the effects of prolonged deprivation of low-voltage fast-wave sleep in the deermouse, peromyscus maniculatus bairdi. | | 1971 | 4353538 |
| sea-level and high-altitude breeding colonies of peromyscus maniculatus sonoriensis. | | 1970 | 5461949 |
| chromosomes of peromyscus (rodentia, cricetidae). ii. the y chromosome of peromyscus maniculatus. | | 1970 | 5412047 |
| the karyotype in peromyscus maniculatus nubiterrae. | | 1969 | 5389197 |
| malignant tumors associated with subcutaneously implanted 60co radioactive wires in peromyscus maniculatus. | | 1969 | 5817789 |
| weights of selected organs of deer mice (peromyscus maniculatus bairdii) from asymptotic laboratory populations. | | 1969 | 5362361 |
| electrophoretic examination of hemoglobin and plasma proteins from three altitude groups of peromyscus maniculatus nerbascensis. | | 1968 | 5651282 |
| the effect of reproductive performance on the domestication of the prairie deermouse, peromyscus maniculatus bairdii. | | 1967 | 28563085 |
| recovery of an adenovirus from a feral rodent peromyscus maniculatus. | | 1967 | 4290459 |
| haemoglobin variants in a species of wild mice-peromyscus maniculatus. | | 1966 | 5914910 |
| distress vocalizations of young in two subspecies of peromyscus maniculatus. | | 1966 | 5930720 |
| bound and free corticosteroid in the plasma of two subspecies of deer mice (peromyscus maniculatus) after exposure to a low ambient temperature. | | 1964 | 14231134 |
| activity rhythm in peromyscus: its influence on rates of recovery from nembutal. | injection of sublethal doses of nembutal (sodium pentobarbital) into deer mice, peromyscus maniculatus rufinus (merriam), at diflerent times in their daily activity cycle revealed large differences in rates of recovery. by taking the phase of the circadian rhythm into account, the accuracy obtained in pharmaceutical and physiological bioassays could be increased. | 1963 | 14075704 |
| age of weaning in two subspecies of deer mice. | weaning age in deer mice is defined as the age at which the young mice maintain or gain weight during a 24-hour period of isolation; mice younger than weaning age lose weight. two subspecies of deer mice differed in weaning age; the age for peromyscus maniculatus bairdii was 18 days; for p. m. gracilis, 24 days. age and food consumption were better predictors of the weaning condition, as defined in terms of weight change with isolation, than body weight. | 1963 | 14032839 |
| the differential effects of chlorpromazine and pentobarbital on two forms of conditioned avoidance behavior in peromyscus maniculatus gracilis. | | 1962 | 14001535 |
| separation of the public symphysis during pregnancy and after treatment with relaxin in two sub-species of peromyscus maniculatus. | | 1961 | 14009892 |
| a comparison of body weight and thyroid gland activity in two subspecies of peromyscus maniculatus from birth to 70 days of age. | | 1961 | 13889806 |
| effect of altitude on endurance running of peromyscus maniculatus. | | 1961 | 13714810 |
| effects of early handling upon adult behavior in two subspecies of deermice, peromyscus maniculatus. | | 1959 | 13641470 |
| the rearing of homozygous hairless deer mice, peromyscus maniculatus gambeli, with a note of superfetation or delayed fertilization. | | 1959 | 13659440 |
| histologic study of the skin of hairless american deer mice (peromyscus maniculatus gambeli). | | 1957 | 13443615 |
| red eyed peromyscus maniculatus. | | 1948 | 18100301 |
| prevalence of tick-borne pathogens in two species of peromyscus mice common in northern wisconsin. | two species of mice, the white-footed mouse, peromyscus leucopus (rafinesque; rodentia: cricetidae) and the woodland deer mouse, peromyscus maniculatus (wagner; rodentia: cricetidae), serve as reservoirs of tick-borne pathogens in many parts of north america. however, the role p. maniculatus plays in the amplification and maintenance of anaplasma phagocytophilum (rickettsiales: ehrlichiaceae) and borrelia burgdorferi (spirochaetales: spirochaetaceae) is not well understood. in northern wisconsin ... | 2018 | 29506103 |
| indirect effects of a large mammalian herbivore on small mammal populations: context-dependent variation across habitat types, mammal species, and seasons. | multiple consumer species frequently co-occur in the same landscape and, through effects on surrounding environments, can interact in direct and indirect ways. these interactions can vary in occurrence and importance, and focusing on this variation is critical for understanding the dynamics of interactions among consumers. large mammalian herbivores are important engineers of ecosystems worldwide, have substantial impacts on vegetation, and can indirectly affect small-mammal populations. however ... | 2018 | 30598804 |
| detection of 'candidatus ehrlichia khabarensis' in rodents and ticks removed from rodents in british columbia, canada. | 'candidatus ehrlichia khabarensis' was first described from rodents and insectivores in the far east territory of khabarovsk on the russian pacific coast. here we report the detection of dna from this microorganism in rodents and fed ticks collected from rodents in british columbia, canada in 2013-2014. 'candidatus ehrlichia khabarensis' was detected in (i) a female ixodes angustus tick collected from a peromyscus maniculatus; (ii) a female dermacentor andersoni tick collected from a perognathus ... | 2020 | 31501035 |
| development and characterization of a sin nombre virus transmission model in peromyscus maniculatus. | in north america, sin nombre virus (snv) is the main cause of hantavirus cardiopulmonary syndrome (hcps), a severe respiratory disease with a fatality rate of 35⁻40%. snv is a zoonotic pathogen carried by deer mice (peromyscus maniculatus), and few studies have been performed examining its transmission in deer mouse populations. studying snv and other hantaviruses can be difficult due to the need to propagate the virus in vivo for subsequent experiments. we show that when compared with standard ... | 2019 | 30795592 |
| detection and evaluation of antibody response to a baylisascaris-specific antigen in rodent hosts with the use of western blotting and elisa. | diagnosis of parasitic diseases that involve tissue-stage larvae is challenging, and serology remains the most effective antemortem test for detecting these infections. baylisascaris procyonis, the raccoon roundworm, is a zoonotic ascarid. raccoons are the usual definitive host, and humans may be infected as accidental hosts. more than 150 species of birds and mammals may act as paratenic hosts, and rodents play an important role in the transmission and maintenance of this parasite in nature. mi ... | 2018 | 30074878 |
| impact of climate change on the small mammal community of the yukon boreal forest. | long-term monitoring is critical to determine the stability and sustainability of wildlife populations, and if change has occurred, why. we have followed population density changes in the small mammal community in the boreal forest of the southern yukon for 46 years with density estimates by live trapping on 3-5 unmanipulated grids in spring and autumn. this community consists of 10 species and was responsible for 9% of the energy flow in the herbivore component of this ecosystem from 1986 to 19 ... | 2019 | 30983064 |
| long-term and interactive effects of different mammalian consumers on growth, survival, and recruitment of dominant tree species. | throughout the world, numerous tree species are reported to be in decline, either due to increased mortality of established trees or reduced recruitment. the situation appears especially acute for oaks, which are dominant features of many landscapes in the northern hemisphere. although numerous factors have been hypothesized to explain reductions in tree performance, vertebrate herbivores and granivores may serve as important drivers of these changes. here, using data from 8- and 14-year-old exc ... | 2020 | 32884658 |
| practical guide to trapping peromyscus leucopus (rodentia: cricetidae) and peromyscus maniculatus for vector and vector-borne pathogen surveillance and ecology. | arthropods pests are most frequently associated with both plants and vertebrate animals. ticks, in particular the blacklegged ticks ixodes scapularis say and ixodes pacificus cooley & kohls (acari: ixodidae), are associated with wildlife hosts and are the primary vectors of lyme disease, the most frequently reported vector-borne disease in the united states. immature blacklegged ticks in the eastern united states frequently use small mammals from the genus peromyscus as hosts. these mice are com ... | 2020 | 33135755 |
| molecular detection of leptospira interrogans and borrelia burgdorferi in wild rodents from mexico. | leptospirosis and lyme borreliosis are zoonotic emerging diseases of global importance and wide distribution. the aim of this study was to detect by molecular testing to leptospira interrogans and borrelia burgdorferi sensu lato in wild rodents from nuevo leon, quintana roo, and campeche, mexico. this study is the first in report to chaetodipus nelsoni, dipodomys merriami, and peromyscus eremicus infected with l. interrogans in mexico. besides, chaetodipus hispidus, heteromys gaumeri, heteromys ... | 2020 | 32639187 |
| humane use of cardiac puncture for non-terminal phlebotomy of wild-caught and released peromyscus spp. | the cardiac puncture technique for obtaining relatively large volume (50-150 µl) blood samples from sedated rodents has been used in research for nearly a century. historically, its use to phlebotomize and then release live rodents was more common. however, recently its use in a non-terminal capacity frequently imparts negative connotations in part because exsanguination of sedated animals via cardiac puncture is now an american veterinary medical association-approved euthanasia technique. this ... | 2020 | 32397470 |
| immature ixodes scapularis (acari: ixodidae) collected from peromyscus leucopus (rodentia: cricetidae) and peromyscus maniculatus (rodentia: cricetidae) nests in northern wisconsin. | the blacklegged tick, ixodes scapularis say, is the primary lyme disease vector in the eastern united states. both immature stages of i. scapularis take blood meals from mice belonging to the genus peromyscus. mice are active during the night and spend the majority of diel periods in nests. thus, immature i. scapularis have a greater opportunity to drop from peromyscus hosts while in nests compared with the forest floor. here, we collected 11 peromyscus nests during a 3-mo period during which th ... | 2020 | 31411327 |
| conservation of the genome-wide recombination rate in white-footed mice. | despite being linked to the fundamental processes of chromosome segregation and offspring diversification, meiotic recombination rates vary within and between species. recent years have seen progress in quantifying recombination rate evolution across multiple temporal and genomic scales. nevertheless, the level of variation in recombination rate within wild populations-a key determinant of evolution in this trait-remains poorly documented on the genomic scale. to address this notable gap, we use ... | 2019 | 31366913 |
| development of homeothermic endothermy is delayed in high-altitude native deer mice (peromyscus maniculatus). | altricial mammals begin to independently thermoregulate during the first few weeks of postnatal development. in wild rodent populations, this is also a time of high mortality (50-95%), making the physiological systems that mature during this period potential targets for selection. high altitude (ha) is a particularly challenging environment for small endotherms owing to unremitting low o2 and ambient temperatures. while superior thermogenic capacities have been demonstrated in adults of some ha ... | 2019 | 31337307 |
| evidence of degradation of hair corticosterone in museum specimens. | researchers increasingly rely on non-invasive physiological indices, such as glucocorticoid (gc) levels, to interpret how vertebrates respond to changes in their environment. recently, hair gcs have been of particular interest, because they are presumed stable over long periods of storage, which may facilitate the study of large-scale spatial and temporal patterns of stress in mammals. in the current study, we evaluated the stability of hair corticosterone levels in museum specimens, and the pot ... | 2018 | 30099031 |
| corticosterone response by peromyscus mice to parasites, reproductive season, and age. | a common response to parasite infestations is increased production of glucocorticoid hormones that regulate immune function. we examined relationships between ectoparasite infestations and fecal corticosterone metabolites (fcm) in deer mice (peromyscus maniculatus). furthermore, we experimentally removed fleas to determine if reductions in ectoparasites affected fcm production. individuals were assigned to control (no flea removal) or treatment (anti-flea application, physical combing) groups an ... | 2020 | 33017585 |
| chronic cold exposure induces mitochondrial plasticity in deer mice native to high altitudes. | small mammals native to high altitude must sustain high rates of thermogenesis to cope with cold. skeletal muscle is a key site of shivering and non-shivering thermogenesis, but the importance of mitochondrial plasticity in cold hypoxic environments remains unresolved. we examined high-altitude deer mice, which have evolved a high capacity for aerobic thermogenesis, to determine the mechanisms of mitochondrial plasticity during chronic exposure to cold and hypoxia, alone and in combination. cold ... | 2020 | 32886797 |
| variation in space and time: a long-term examination of density-dependent dispersal in a woodland rodent. | dispersal is a fundamental ecological process that can be affected by population density, yet studies report contrasting effects of density on propensity to disperse. in addition, the relationship between dispersal and density is seldom examined using densities measured at different spatial scales or over extensive time series. we used 51 years of trapping data to examine how dispersal by wild deer mice (peromyscus maniculatus) was affected by changes in both local and regional population densit ... | 2020 | 32809054 |
| sars-cov-2 infection, neuropathogenesis and transmission among deer mice: implications for reverse zoonosis to new world rodents. | coronavirus disease-19 (covid-19) emerged in november, 2019 in china and rapidly became pandemic. as with other coronaviruses, a preponderance of evidence suggests the virus originated in horseshoe bats (rhinolophus spp.) and likely underwent a recombination event in an intermediate host prior to entry into human populations. a significant concern is that sars-cov-2 could become established in secondary reservoir hosts outside of asia. to assess this potential, we challenged deer mice (peromyscu ... | 2020 | 32793912 |
| oral vaccination with recombinant vesicular stomatitis virus expressing sin nombre virus glycoprotein prevents sin nombre virus transmission in deer mice. | sin nombre virus (snv) is the major cause of hantavirus cardiopulmonary syndrome (hcps) in north america, a severe respiratory disease with a high fatality rate. snv is carried by peromyscus maniculatus, or deer mice, and human infection occurs following inhalation of aerosolized virus in mouse excreta or secreta, often in peri-domestic settings. currently there are no fda approved vaccines or therapeutics for snv or any other hantaviruses, therefore prevention of infection is an important means ... | 2020 | 32733817 |
| parasite species co-occurrence patterns on peromyscus: joint species distribution modelling. | hosts are often infested by multiple parasite species, but it is often unclear whether patterns of parasite co-occurrence are driven by parasite habitat requirements or parasite species interactions. using data on infestation patterns of ectoparasitic arthropods (fleas, trombiculid mites, cuterebrid botflies) from deer mice (peromyscus maniculatus), we analyzed species associations using joint species distribution modelling. we also experimentally removed a flea (orchopeas leucopus) from a subse ... | 2020 | 32637312 |
| assessment of the stress response in north american deermice: laboratory and field validation of two enzyme immunoassays for fecal corticosterone metabolites. | stress physiology is commonly employed in studies of wildlife ecology and conservation. accordingly, we need robust and suitable methods to measure stress physiology in the field. fecal cortisol/corticosterone metabolites (fcms) are now increasingly being used to non-invasively evaluate adrenocortical activity; a measure of stress physiology. however, immunoassays that measure fcms must be appropriately validated prior to their use and factors that can influence fcms, such as trap-induced stress ... | 2020 | 32630075 |
| large nest building and high marble-burying: two compulsive-like phenotypes expressed by deer mice (peromyscus maniculatus bairdii) and their unique response to serotoninergic and dopamine modulating intervention. | this study aimed to further dissect the deer mouse (peromyscus maniculatus bairdii) model of compulsive-like behavior with respect to two persistent-like behavioral phenotypes viz. large nest building (lnb) and high marble-burying (hmb), which may be relevant to understanding the neurobiology of different symptom dimensions in obsessive-compulsive and related disorders. since lnb is sensitive to chronic, high dose escitalopram intervention but hmb is not, we assessed whether the two behaviors co ... | 2020 | 32619566 |
| body size trends in response to climate and urbanization in the widespread north american deer mouse, peromyscus maniculatus. | body size decline is hypothesized to be a key response to climate warming, including warming driven by urban heat islands. however, urbanization may also generate selective gradients for body size increases in smaller endotherms via habitat fragmentation. here we utilize a densely sampled, multi-source dataset to examine how climate and urbanization affect body size of peromyscus maniculatus (pema), an abundant rodent found across north america. we predicted pema would conform to bergmann's rule ... | 2020 | 32483167 |
| penicillium diversity in canadian bat caves, including a new species, p. speluncae. | penicillium species were commonly isolated during a fungal survey of bat hibernacula in new brunswick and quebec, canada. strains were isolated from arthropods, bats, rodents (i.e. the deer mouse peromyscus maniculatus), their dung, and cave walls. hundreds of fungal strains were recovered, of which penicillium represented a major component of the community. penicillium strains were grouped by colony characters on blakeslee's malt extract agar. dna sequencing of the secondary identification mark ... | 2020 | 32467912 |
| coordinated changes across the o2 transport pathway underlie adaptive increases in thermogenic capacity in high-altitude deer mice. | animals native to the hypoxic and cold environment at high altitude provide an excellent opportunity to elucidate the integrative mechanisms underlying the adaptive evolution and plasticity of complex traits. the capacity for aerobic thermogenesis can be a critical determinant of survival for small mammals at high altitude, but the physiological mechanisms underlying the evolution of this performance trait remain unresolved. we examined this issue by comparing high-altitude deer mice (peromyscus ... | 2020 | 32429808 |
| adaptive shifts in gene regulation underlie a developmental delay in thermogenesis in high-altitude deer mice. | aerobic performance is tied to fitness as it influences an animal's ability to find food, escape predators, or survive extreme conditions. at high altitude, where low o2 availability and persistent cold prevail, maximum metabolic heat production (thermogenesis) is an aerobic performance trait that is closely linked to survival. understanding how thermogenesis evolves to enhance survival at high altitude will yield insight into the links between physiology, performance, and fitness. recent work i ... | 2020 | 32243546 |
| long-term rodent surveillance after outbreak of hantavirus infection, yosemite national park, california, usa, 2012. | in 2012, a total of 9 cases of hantavirus infection occurred in overnight visitors to yosemite valley, yosemite national park, california, usa. in the 6 years after the initial outbreak investigation, the california department of public health conducted 11 rodent trapping events in developed areas of yosemite valley and 6 in tuolumne meadows to monitor the relative abundance of deer mice (peromyscus maniculatus) and seroprevalence of sin nombre orthohantavirus, the causative agent of hantavirus ... | 2020 | 32091360 |
| ontogenesis of evolved changes in respiratory physiology in deer mice native to high altitude. | high-altitude environments are cold and hypoxic, and many high-altitude natives have evolved changes in respiratory physiology that improve o2 uptake in hypoxia as adults. altricial mammals undergo a dramatic metabolic transition from ectothermy to endothermy in early post-natal life, which may influence the ontogenetic development of respiratory traits at high altitude. we examined the developmental changes in respiratory and haematological traits in deer mice (peromyscus maniculatus) native to ... | 2020 | 32054682 |
| evaluation of fluralaner as an oral acaricide to reduce tick infestation in a wild rodent reservoir of lyme disease. | lyme disease (ld) is an increasing public health threat in temperate zones of the northern hemisphere, yet relatively few methods exist for reducing ld risk in endemic areas. disrupting the ld transmission cycle in nature is a promising avenue for risk reduction. this experimental study evaluated the efficacy of fluralaner, a recent oral acaricide with a long duration of effect in dogs, for killing ixodes scapularis ticks in peromyscus maniculatus mice, a known wildlife reservoir for borrelia bu ... | 2020 | 32054498 |
| leukocyte evaluation of the free-ranging deermouse (peromyscus maniculatus) from montana, usa. | we generated reference ranges for seasonal leukocyte differential counts of the free-ranging deermouse (peromyscus maniculatus) from montana, us. blood was collected from the retro-orbital capillary sinus of deermice after topical anesthesia with proparacaine. although season influenced lymphocyte, neutrophil, and monocyte absolute counts, sex and reproductive status did not. | 2020 | 32053415 |
| effects of trap confinement on personality measurements in two terrestrial rodents. | in recent years, consistent individual differences in behavior, or personalities, have been a topic of increasing interest as researchers strive to understand and predict the responses of individuals and populations to anthropogenic changes. behavioral studies in wild populations often require that animals are live trapped before behavioral observation can occur, and this is especially true in studies investigating animal personalities. however, it is unknown whether the amount of time confined ... | 2020 | 31986141 |
| the underappreciated role of rodent generalists in fungal spore dispersal networks. | animals are often the primary dispersers of seeds and fungal spores. specialist species that consume fruits or fungal fruiting bodies (sporocarps) as their main food source are thought to play a more important role in dispersal networks compared to generalist species. however, dispersal networks are often based on occurrence data, overlooking the influence of animal abundance and dispersal effectiveness on network interactions. using rodent-mycorrhizal fungi networks, we determined how diet spec ... | 2020 | 31943145 |
| naturalistic operant responses in deer mice (peromyscus maniculatus bairdii) and its response to outcome manipulation and serotonergic intervention. | investigating the motivational triggers underlying naturalistic compulsive-like behavior is generally regarded as challenging. to this extent, the current study aimed to establish a proof-of-concept for future investigation by probing unconditioned and naturalistic operant responses aimed at obtaining nesting material by normal (nnb) and large (lnb) nest building deer mice (peromyscus maniculatus bairdii). lnb mice and nnb controls were individually placed in cages equipped with a lever-operated ... | 2020 | 31895062 |
| variation in the density of oxytocin receptors in the brain as mechanism of adaptation to specific social and reproductive strategies. | most species have predominant forms of social and reproductive behavior driven by many years of selection pressures and evolution. for example, rodent species can live in small or large groups, behave more tolerant or aggressively toward conspecifics (including newborns), and form or not bonds with other members of the group (including sexual partners). any of those behavioral adaptations could result in good fitness for the species, but could also require compromises such as sharing resources, ... | 2020 | 31734142 |
| physiological and genomic evidence that selection on the transcription factor epas1 has altered cardiovascular function in high-altitude deer mice. | evolutionary adaptation to extreme environments often requires coordinated changes in multiple intersecting physiological pathways, but how such multi-trait adaptation occurs remains unresolved. transcription factors, which regulate the expression of many genes and can simultaneously alter multiple phenotypes, may be common targets of selection if the benefits of induced changes outweigh the costs of negative pleiotropic effects. we combined complimentary population genetic analyses and physiolo ... | 2019 | 31697676 |
| natural compulsive-like behaviour in the deer mouse (peromyscus maniculatus bairdii) is associated with altered gut microbiota composition. | obsessive-compulsive disorder (ocd) is a psychiatric illness that significantly impacts affected patients and available treatments yield suboptimal therapeutic response. recently, the role of the gut-brain axis (gba) in psychiatric illness has emerged as a potential target for therapeutic exploration. however, studies concerning the role of the gba in ocd are limited. to investigate whether a naturally occurring obsessive-compulsive-like phenotype in a rodent model, that is large nest building i ... | 2020 | 31663195 |
| the genetics of morphological and behavioural island traits in deer mice. | animals on islands often exhibit dramatic differences in morphology and behaviour compared with mainland individuals, a phenomenon known as the 'island syndrome'. these differences are thought to be adaptations to island environments, but the extent to which they have a genetic basis or instead represent plastic responses to environmental extremes is often unknown. here, we revisit a classic case of island syndrome in deer mice (peromyscus maniculatus) from british columbia. we first show that s ... | 2019 | 31662081 |
| developmental delay in shivering limits thermogenic capacity in juvenile high-altitude deer mice (peromyscus maniculatus). | many endotherms native to cold and hypoxic high-altitude (ha) environments have evolved a highly vascularized and aerobic skeletal muscle. this specialized muscle phenotype contributes via shivering to an enhanced capacity for aerobic thermogenesis (cold-induced v̇o2,max). however, it is unclear how selection at ha for shivering thermogenesis acts early in the development of small altricial mammals, which are born with immature skeletal muscles and without the capacity for homeothermic endotherm ... | 2019 | 31562187 |
| new exposure location for hantavirus pulmonary syndrome case, california, usa, 2018. | we describe a case of hantavirus pulmonary syndrome in a patient exposed to sin nombre virus in a coastal county in california, usa, that had no previous record of human cases. environmental evaluation coupled with genotypic analysis of virus isolates from the case-patient and locally trapped rodents identified the likely exposure location. | 2019 | 31538924 |
| regulation of catecholamine release from the adrenal medulla is altered in deer mice (peromyscus maniculatus) native to high altitudes. | high-altitude natives have evolved to overcome environmental hypoxia and provide a compelling system to understand physiological function during reductions in oxygen availability. the sympathoadrenal system plays a key role in responses to acute hypoxia, but prolonged activation of this system in chronic hypoxia may be maladaptive. here, we examined how chronic hypoxia exposure alters adrenal catecholamine secretion and how adrenal function is altered further in high-altitude natives. population ... | 2019 | 31242021 |
| evolution of physiological performance capacities and environmental adaptation: insights from high-elevation deer mice (peromyscus maniculatus). | analysis of variation in whole-animal performance can shed light on causal connections between specific traits, integrated physiological capacities, and darwinian fitness. here, we review and synthesize information on naturally occurring variation in physiological performance capacities and how it relates to environmental adaptation in deer mice (peromyscus maniculatus). we discuss how evolved changes in aerobic exercise capacity and thermogenic capacity have contributed to adaptation to high el ... | 2019 | 31138949 |
| plague-positive mouse fleas on mice before plague induced die-offs in black-tailed and white-tailed prairie dogs. | plague is a lethal zoonotic disease associated with rodents worldwide. in the western united states, plague outbreaks can decimate prairie dog (cynomys spp.) colonies. however, it is unclear where the causative agent, yersinia pestis, of this flea-borne disease is maintained between outbreaks, and what triggers plague-induced prairie dog die-offs. less susceptible rodent hosts, such as mice, could serve to maintain the bacterium, transport infectious fleas across a colony, or introduce the patho ... | 2019 | 30994405 |
| transmissible vaccines in heterogeneous populations: implications for vaccine design. | transmissible vaccines may provide a promising solution for improving the control of infectious disease, particularly zoonotic pathogens with wildlife reservoirs. although it is well known that heterogeneity in pathogen transmission impacts the spread of infectious disease, the effects of heterogeneity on vaccine transmission are largely unknown. here we develop and analyze a mathematical model that quantifies the potential benefits of a transmissible vaccine in a population where transmission i ... | 2019 | 30859117 |