| [electroophthalmological characteristics in ischemic retinopathy (author's transl)]. | in the erg the b-wave and the oscillatory potentials are reduced or nonrecordable in ischemic retinopathy. the photopic b-wave appeared to be more sensitive than the scotopic b-wave. in the eog the slow oscillation is reduced. these clinical observations are in accordance with the results of experimental studies in rhesus monkeys. | 1979 | 113610 |
| ultrastructure of normal monkey liver. | the normal ultrastructure of the liver of rhesus and cynomolgus monkeys is described. a classification of type a and b periportal hepatocytes is introduced together with a discussion of the high incidence of mitochondrial abnormalities. it is suggested that the rhesus monkey is more suitable as an experimental model than the cynomolgus since its liver ultrastructure is less variable. | 1979 | 113618 |
| ultrastructure of rhesus monkey renomedullary interstitial cells. | the fine structure of rhesus monkey renomedullary interstitial cells was studied by electron microscopy. these stellate cells contained variable numbers of lipid droplets, moderate numbers of mitochondria, moderate amounts of rough endoplasmic reticulum, and prominent golgi zones. in rare instances, apparent release of lipid droplets into the interstitium was observed. the most prominent feature of the interstitial cells was larger nuclear pseudoinclusions which were observed in a high proportio ... | 1979 | 113623 |
| normal values for some whole blood and serum components of grivet monkeys (cercopithecus aethiops). | normal values for a number of blood components of grivet monkeys are reported. haematological data and values for glucose, cholesterol and urea are similar to those of rhesus monkeys. activities of alkaline phosphatase (1526 u/l), glutamine oxaloacetate transaminase (30.9 u/l), glutamine pyruvate transaminase (13.7 u/l), lactate dehydrogenase (629 u/l), alpha-hydroxybutyrate dehydrogenase (175 u/l), creatine phosphokinase (227 u/l), gamma-glutamyl transpeptidase (38.7 u/l) and sorbitol dehydroge ... | 1979 | 113624 |
| genesis of the primate neostriatum: [3h]thymidine autoradiographic analysis of the time of neuron origin in the rhesus monkey. | | 1979 | 113693 |
| maternal-fetal transfer of melatonin in the non-human primate. | melatonin was detected in the circulation of the near-term rhesus monkey (macaca mulatta) and baboon (papio papio) fetus. we determined whether the source could be the mother by studying placental transfer of melatonin in the rhesus monkey. when [3h]melatonin was administered i.v. to the mother it promptly appeared in the fetal circulation; the rates of disappearance of [3h]melatonin in the maternal and fetal circulations were parallel. the rapid decrease in circulating [3h]melatonin was associa ... | 1979 | 113767 |
| ultradian barpressing for rewarding brain stimulation in rhesus monkeys. | | 1979 | 113793 |
| the effects of blood sludging upon short-term memory in rats and rhesus monkeys: an evaluation of its role in age-related cognitive declines. | | 1979 | 113794 |
| sexual behavior in long-term vasectomized male rhesus monkeys. | | 1979 | 113795 |
| experiential variables influencing play, foot-clasp mounting and adult sexual competence in male rhesus monkeys. | | 1979 | 113802 |
| genetic analysis of 23 rhl-a histocompatibility antigens of the rhesus monkey. | the lymphocytotoxicity of 116 rhesus monkey alloantisera was evaluated in 92 unrelated rhesus monkeys and in 33 pedigreed rhesus families. the study was conducted using a standard complement-dependent microcytotoxocity assay. a computer-assisted chi2 analysis of the reactivity of these sera in unrelated monkeys generated 23 groups of highly correlated antisera. the two-locus model of the mammalian major histocompatibility complex was assumed for the monkey, and genetic criteria for rhl-a antigen ... | 1979 | 113914 |
| the disposition of [14c]iprindole in man, dog, miniature swine, rhesus monkey and rat. | 1. absorption of a single oral dose of [14c]iprindole was rapid in rats, rhesus monkeys, miniature swine, dogs and human volunteers. in all species except the rat, most of the radioactivity in the blood resided in the plasma. small amounts of unchanged iprindole were detected in the plasma of rats and rhesus monkeys but not in man and miniature swine. 2. radioactivity was excreted mainly in the urine of man, miniature swine and rhesus monkey, but in the faeces of rat and dog. 3. urinary radioact ... | 1979 | 113942 |
| transmission of sarcocystis suihominis from humans to swine to nonhuman primates (pan troglodytes, macaca mulatta, macaca irus). | sporocysts of sarcocystis suihominis obtained from human feces were used to infect swine. heart, tongue, and skeletal muscle from experimentally infected and noninfected control swine were fed via stomach tube to nonhuman primates including chimpanzees (pan troglodytes), rhesus monkeys (macaca mulatta), and cynomolgus monkeys (macaca irus). all primates fed infected swine tissues shed sporocysts beginning 13 to 15 days postinfection and were still shedding sporocysts at the conclusion of the exp ... | 1979 | 113949 |
| cortical potentials associated with vocalization in the rhesus monkey. | cortical potentials associated with vocalization have been investigated in two rhesus monkeys. in both animals a slow negative potential shift beginning approximately 1 sec prior to the onset of vocalization has been observed in transcortical recordings from precentral areas. it is suggested that this slow potential change might be the phylogenetic antecedent of the voluntary control of speech in humans. | 1977 | 113982 |
| neuronal-vascular relationships in the raphe nuclei, locus coeruleus, and substantia nigra in primates. | a fluorescence histochemical and electron microscopic study of the monoaminergic cell groups in the squirrel monkey and rhesus monkey brains has revealed the direct apposition of blood vessels to perikarya and dendrites of monoaminergic neurons. capillaries and small arterioles or venules, ranging from 8-50 microns in diameter, showed perikarya and dendrites abutting the basement membrane without evidence of glial interposition. this neuronal-vascular relationship was present in 20% to 30% of th ... | 1979 | 114041 |
| studies on the 2,4-diamino-6 substituted quinazolines. i. antimalarial activities of 2,4-diamino-6-[(3,4-dichlorobenzyl)-nitrosoamino]-quinazoline (ci-679) as exhibited in rhesus monkeys infected with the ro or ro/pm strains of plasmodium cynomolgi. | this report summarizes the results of appraisals of various activities of ci-679 (a 2,4-diamino-6-amino-substituted quinazoline) in rhesus monkeys infected with the ro and ro/pm strains of plasmodium cynomolgi. in subjects inoculated with sporozoites, ci-679, administered in appropriate schedules in doses up to and including the maximum tolerated level, neither prevented development of infections with these strains nor cured those already established. although these evaluations showed that ci-67 ... | 1979 | 114064 |
| sarcocystis in man: a review and report of five cases. | sarcocystis was identified in biopsy specimens of skeletal muscle from two adults in singapore and one in bombay, and in muscle obtained at autopsy from an adult in uganda, and in the heart of a child in costa rica. review of case reports revealed that in seven reported cases, including three reported by lindemann, non-parasite objects were misinterpreted as sarcocysts; in four instances organisms of undetermined classification were described, and in 35 cases true sarcocysts were observed. among ... | 1979 | 114067 |
| characterization of the exfoliative antispermatogenic agent 1-(2,4-dichlorobenzyl)-h-indazole-3-carboxylic acid in the rhesus monkey. | the effects of oral doses of 1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylic acid (dica) on spermatogenesis in the rhesus monkey (macaca mulatta) was studied. four animals given five daily 50 mg/kg doses or three or five daily 500 mg/kg doses showed that dica was an exfoliating antispermatogenic compound. the inhibition of spermatogenesis was only partially reversible following 500 mg/kg doses of dica. weekly and monthly 50 mg/kg doses of dica only partially inhibiting spermatogenesis as measure ... | 1979 | 114129 |
| the disposition of 3-methyl-2,3-dihydro-9h-isoxazolo[3,2-b]-quinazolin-9-one (w-2451). | 3-methyl-2,3-dihydro-9h-isoxazolo[3,2-b]quinazolin-9-one was readily absorbed, metabolized and eliminated in rat, dog, monkey and man. the radioactivity elimination after i.v. or p.o. administration of w-2451-14c in rats was biphasic with corresponding half-lives of 1.8 and 8.7 hours. plasma half-lives of w-2451 in the dog, rhesus monkey and man were 1.4, 1.2 and 3.2 hours, respectively. in the rat, excretion via the urine was predominant, no significant accumulation in tissue occurred. the only ... | 1979 | 114130 |
| pharmacokinetics and metabolism of cefazedone in wistar rat, beagle dog and rhesus monkey. | | 1979 | 114189 |
| varied effects of dietary sucrose and cholesterol on serum lipids, lipoproteins and apolipoproteins in rhesus monkeys. | serum lipid, lipoproteins, apolipoproteins and plasma insulin and glucose were studied in rhesus monkeys (macaca mulatta) fed high sucrose diets (69%, w/w), with and without added cholesterol. when compared to basal diet, a high sucrose diet with no added cholesterol fed for 6 weeks increased serum total cholesterol and triglycerides by factors of 1.2 and 2.8, respectively. cholesterol supplementation of sucrose diets increased the serum total cholesterol levels by a factor of 2.2 and decreased ... | 1979 | 114194 |
| hormonal regulation of ovarian folliculogenesis in rhesus monkeys. ii. serum concentrations of estradiol-17 beta and follicle stimulating hormone associated with growth and identification of the preovulatory follicle. | | 1979 | 114242 |
| elevation of blood lead concentration by confinement in the rhesus monkey. | rhesus monkeys were exposed to lead (pb) acetate under various regimens during the first 12 months of life. at 30 months of age, these animals and unexposed controls were confined to an unfamiliar experimental chamber for one week. serum cortisol concentration and pb concentration in whole blood (pbb) were measured prior to, during, and after this confinement. cortisol concentrations rose 60--90% within 2 hours of confinement, and declined to baseline levels after 98 hours of confinement. mean b ... | 1979 | 114260 |
| discriminative vocal conditioning in rhesus monkeys: evidence for volitional control? | | 1979 | 114270 |
| enhancement of self-stimulation behavior in rats and monkeys after chronic neuroleptic treatment: evidence for mesolimbic supersensitivity. | the effect of chronic neuroleptic drug treatment on self-stimulation of the mesolimbic dopamine system was tested. rats with electrodes implanted into the ventral tegmental nucleus (a10 cell body area) were treated with haloperidol for three weeks. afterwards, the rats showed a 35% increase in self-stimulation rate, as compared to pre-drug control rates. this increase persisted for three weeks after drug withdrawal before returning to baseline rates. rats treated for three weeks with the atypica ... | 1979 | 114275 |
| [stereotype and plasticity of utterances in gibbons (hylobates concolor leucogenys)]. | the "great call" of adult male and female hylobates concolor leucogenys was studied in different conditions of social stimulation, using quantitative (i. e. sonographic) analysis. vocal sequences are generally made up of mixed sounds, appearing in a fixed order and constituting a species-specific character. qualitative diversification appears in the repetition of sequences. different social situations alter parameters of the calling pattern: especially the length and intensity of homologous modu ... | 1979 | 114327 |
| treatment of rhesus monkeys (macaca mulatta) with intrauterine devices loaded with levonorgestrel. | the effects of levonorgestrel-loaded plastic intrauterine devices on endometrial morphology were investigated in 15 rhesus monkeys for 14 weeks. the devices were designed to release 25 microgram of the hormone per day and were inserted in the uterus by hysterotomy. control animals were sham operated or received inert placebo devices. with the levonorgestrel-releasing devices, widespread changes in endometrial morphology were seen. these changes included atrophy of the endometrial mucosal and gla ... | 1979 | 114355 |
| clinical experiences with repeated oral administration of l-alpha-acetylmethadol (laam) in the rhesus monkey. | | 1978 | 114383 |
| effects of dietary cadmium on rhesus monkeys. | ten male rhesus monkeys, each weighing 3.5 kg, were divided into four groups of 3, 3, 2, and 2, and were fed daily with 100 g pelleted food containing 300, 30, 3, and 0 ppm cadmium, respectively. urine samples were collected every 2 weeks and blood samples every 4 weeks. one monkey each of the 300 and 30 ppm groups was autopsied for pathological examination and tissue cadmium determination at the week 24 of the experiment; the remaining 8 animals were killed after 55 weeks. the lowest exposed gr ... | 1979 | 114386 |
| fusional vergence ranges of the monkey: a behavioral study. | fusional vergence ranges were behaviorally determined for two rhesus monkeys and two human subjects using random dot stereograms as stimuli. the subject performed a two-alternative forced choice form discrimination of discretely presented stimuli and the fusional vergence stimulus was changed during the intertrial intervals. the fusional vergence measurements for the monkey were similar to those for the human subjects. | 1979 | 114404 |
| cortical field of origin of the anterior commissure of the rhesus monkey. | | 1979 | 114407 |
| vasectomy: consequences of autoimmunity to sperm antigens. | data from studies examining the effects of vasectomy in a large number of nonhuman primates vasectomized for periods ranging up to 14 years are summarized, and these findings and speculations are used as a framework with which to review the subject of autoimmunity and vasectomy. attention is directed to autoimmunity to sperm antigens following vasectomy (factors affecting antisperm antibody levels, characteristics of circulating antisperm antibodies, antisperm antibodies in seminal plasma, and ... | 1979 | 114428 |
| inhibition of ovarian, placental, and adrenal steroidogenesis in the rhesus monkey by trilostane. | trilostane inhibits adrenal, ovarian, and placental steroidogenesis when administered orally to rhesus monkeys. by inhibiting 3 beta-hydroxysteroid dehydrogenase activity, it causes an increase in circulating levels of pregnenolone. trilostane reverses the stimulation of luteal progesterone production and the delay in onset on menstruation induced by human chorionic gonadotropin. in pregnant monkeys it reduces circulating progesterone levels and is an effective interceptive agent if given for 5 ... | 1979 | 114429 |
| [comparative study of the radiosensitivity of monkey chromosomes in cellular irradiation in vivo and in vitro]. | chromosome radiosensitivity was studied in the primary culture of peripheral blood lymphocytes and epithelial kidney cells of macaca mulatta monkeys after gamma-irradiation in vivo and in vitro. the results of the experiments show that there are no differences in aberration yields produced in both types of somatic cells under gamma-irradiation in vivo and in vitro. | 1979 | 114453 |
| the striate projection zone in the superior temporal sulcus of macaca mulatta: location and topographic organization. | in the rhesus monkey, the caudal portion of the superior temporal sulcus (sts) receives a direct projection from lateral striate cortex, the striate are representing central vision. the present study was undertaken to determine whether sts also receives a direct projection from areas of striate cortex representing peripheral vision, with the intent of defining the entire striate projection zone in sts as well as providing information regarding a possible topographic organization within this seco ... | 1979 | 114557 |
| warm fibers innervating palmar and digital skin of the monkey: responses to thermal stimuli. | 1. three hundred fourteen warm fibers innervating the glabrous skin of the monkey's hand were isolated by dissection in the median and ulnar nerves in two species, macaca mulatta and m. nemestrina. fiber samples in the two species were functionally similar and uniform in their properties. their mean conduction velocity of 1.2 m/s (sd 0.5; n = 50) implies that these warm fibers were all unmyelinated. 2. a parametric study of the responses of warm fibers to near-rectangular warming and cooling pul ... | 1979 | 114608 |
| antimalarials. 11. synthesis of 3- and 5-aminoquinolines as potential antimalarials. | a series of 3-quinolinediamines (1g, 2c, and 3e) structurally related to primaquine and 4-methylprimaquine have been prepared and tested for antimalarial activity against plasmodium berghei in mice and antileishmanial activity against leishmania donovani in the hamster. all were inactive. in addition, three 5-quinolinediamines (4b, 5, and 6) were prepared. all were inactive against leishmania donovani in hamsters. one of the examples, 6, was curative against plasmodium cynmolgi in the rhesus mon ... | 1979 | 114654 |
| central sites controlling pituitary secretion in the rhesus monkey. | | 1979 | 114716 |
| association of tritiated ovarian steroids with the rhesus monkey brain. | | 1979 | 114717 |
| experimental arteriosclerosis in rhesus monkeys induced by multiple risk factors: cholesterol, vitamin d, and nictotine. | forty-four rhesus monkeys were given various regimens involving three vasotoxic factors: dietary hypercholesteremia, hypervitaminosis d2 and nicotinism for period ranging from 14 to 62 weeks. when administered singly, no or only early disease was observed. the combined three "risk factor" group demonstrated the most impressive arteriosclerosis. major arteriosclerotic changes: fat, calcium and mensenchyme of thirty standardized segments of aorta, coronary and limb arteries of all monkeys were gra ... | 1979 | 114963 |
| comparison of behavioral effects of systemic l-dopa and intracranial dopamine in mesolimbic forebrain of nonhuman primates. | the systemic administration of l-dopa and carbidopa to six rhesus and four squirrel monkeys produced an initial period of depressed activity followed by increased locomotion, hypervigilance, involuntary oral-facial movements and a gnawing syndrome. the squirrel monkey exhibited a depressed phase, locomotor stimulation, searching behavior, stereotypic grooming and gnawing syndrome. most of these activities were prevented by pretreatment with 0.1 mg/kg haloperidol. bilateral injection of 100 micro ... | 1979 | 115011 |
| reversal learning deficits in young monkeys exposed to lead. | the reversal learning capacity of young rhesus monkeys in visual discrimination tasks was examined during daily exposure to dietary lead acetate throughout the first year of life. while not affected in physical development, all lead-treated monkeys showed performance deficits on reversal learning tasks. these deficits were independent of lead-induced changes in motivation. over a series of problems, the overall learning rate of monkeys with blood lead concentrations in the range of 70-90 microgr ... | 1979 | 115012 |
| ethanol drinking by rhesus monkeys with concurrent access to water. | three monkeys were provided concurrent access to water and ethanol in concentrations of either 8, 16 or 32% (w/v) during daily 3-hr sessions. the monkeys were those for whom ethanol had been established as a reinforcer in an earlier study in which only ethanol or water was available. ethanol was preferred to water at all concentrations and volume of ethanol consumed was inversely related to ethanol concentration. quantity of ethanol (g/kg of body wt.) consumed remained relatively constant, and b ... | 1979 | 115013 |
| effects of response-contingent clock stimuli on behavior maintained by intravenous codeine in the rhesus monkey. | response-contingent brief presentations of clock stimuli differentially correlated with food availability altered rates of codeine-maintained lever pressing. rhesus monkeys performed under a two lever multiple schedule: multiple fixed interval clock 5 min variable interval 2 min. different colored lights were presented during successive 75 sec period of the fixed-interval clock component. lever pressing under the fi clock schedule was maintained by presentation of 1 g noyes pellets, and lever pr ... | 1979 | 115015 |
| an improved method for embedding brain tissue in albumin-gelatin. | a new modification of the snodgrass-dorsey (1963) albumin embedding method is described. formalin fixed brains of various ages of rhesus monkey (macaca mulatta) were sunk in 10% phosphate buffered formalin which contained 30% sucrose, and then embedded in a 3% gelatin, 30% egg albumin solution which had been centrifuged to ensure uniformity. the albumin-gelatin was hardened in formaldehyde fumes and blocks cut frozen at 10-40 micron. sections thus prepared can be handled easily and mounted witho ... | 1979 | 115116 |
| intercellular junctions in the rhesus monkey pars distalis. | four rhesus monkey pituitary glands were examined by transmission electron microscopy. three types of intercellular junctions, desmosomes, hemidesmosomes and zonula adherens-type junctions, were observed between adjacent granular cells, folliculo-stellate cells, and joining a folliculo-stellate cell with a granular cell. demosomes were most commonly observed between granular cells while the zonula adherens-type junctions were generally found between the folliculo-stellate cells. | 1979 | 115336 |
| bile studies after liver transplantation. | an analysis of bile composition following orthotopic liver transplantation in the rhesus monkey showed that during rejection only small quantities of viscid bile were produced and that this was associated with increased cholesterol saturation. bile composition in patients after liver transplantation also showed that bile was supersaturated with cholesterol in the early postoperative period while the enterohepatic circulation of bile acids was interrupted by a draining t tube. however, further st ... | 1979 | 115368 |
| suprathreshold retinal damage due to single 6 picosecond 1060 nm laser light pulses. | the retinas of rhesus monkeys were exposed to 6 ps laser light pulses at 1060 nm at 62 and 95 muj. lesions were examined by light and transmission and scanning electron microscopy. evidence of damage was seen in all retinal layers, being most severe in the photoreceptor inner and outer segments. in addition to damage mechanisms previously proposed, it is suggested that the peak power flux density achieved with extremely short pulses may lead to some absorbance by inner retinal layers. | 1979 | 115454 |
| measurement of spatial behavior: methodology applied to rhesus monkeys, neon tetras, communal and solitary spiders, cockroaches, and gnats in open fields. | | 1979 | 115455 |
| reinforcing properties of nicocodine in the rhesus monkey. | the present study demonstrates that nicocodine is self-administered by the rhesus monkey in cross self-administration experiments. the minimum reinforcing dose is 10 times higher than that of codeine and 100 times higher than that of heroin. at reinforcing doses the rate of self-administered infusions of nicocodine is comparable with those of codeine. further experiments are necessary to rank order nicocodine as to its positive reinforcing properties among the opiate-like compounds. on the other ... | 1979 | 115478 |
| application of linear system analysis to the horizontal vestibulo-ocular reflex of the alert rhesus monkey using pseudorandom binary sequence and single frequency sinusoidal stimulation. | horizontal eye movements of the alert rhesus monkey resulting from both pseudorandom binary sequence (prbs) and single frequency sinusoidal rotational stimulation were analyzed using a pdp 11/40 computer in order to generate gain, phase, and coherence estimates at discrete frequencies between 0.008 and 1.28 hz. a computer simulation of vestibular induced eye movements was used to validate our analysis procedures and to determine the effects of digital noise. frequency domain transfer functions d ... | 1979 | 115503 |
| sexual behavior in male rhesus monkeys elicited by electrical stimulation of preoptic and hypothalamic areas. | electrical stimulation of the preoptic area, lateral hypothalamus or dorsomedial nucleus of the hypothalamus (dmh) has produced sexual behavioral responses in 11 male rhesus monkeys. at a short latency following the onset of each train of stimulation, the stimulated males would mount estrogen-treated, receptive females. quantitative measures of the elicited sexual behavior, in 4 males, were applied to describe differences between the effect of preoptic and dmh stimulation on male sexual performa ... | 1979 | 115544 |
| vestibular projections to the monkey thalamus: an autoradiographic study. | vestibulothalamic projections were studied in the monkey (macaca mulatta) by injecting anerograde trace substances (radioactive leucine and proline) into the vestibular nuclear complex. terminal labelling was found bilaterally mainly in the nucleus ventroposterior lateralis pars oralis (vplo) and to a lesser extent in the nucleus ventroposterior inferior (vpi) and nucleus ventralis lateralis pars caudalis (vlc). the labelling was sparse, and scattered over wide areas. the vestibular origin of th ... | 1979 | 115546 |
| renal tubular transport of methotrexate in the rhesus monkey and dog. | the mechanism and localization of renal transport of methotrexate (mtx) were studied in the rhesus monkey and the dog. it was found that in both animals mtx was bound with plasma protein in a range of 50 to 68% varying with the mtx plasma concentration. paper chromatographic analysis showed that a negligible amount of mtx was metabolized. the excretion of mtx in rhesus monkey was mainly by tubular secretion which was blocked by probenecid, but in the dog a bidirectional transport mechanism for m ... | 1979 | 115582 |
| the subcellular distribution of gold in monkey liver, kidney and spleen, in vivo. | 1. the subcellular distribution of gold in the livers, kidney cortex and the spleens of rhesus monkeys was determined at 2, 10 and 20 days after the administration of sodium (195au)-aurothiomalate. the serum gold levels were also determined over the period of study. 2. with the continued decrease in the serum gold levels from day 1 to day 20, a continued increase in the tissue levels of the organs studied was observed. the corresponding subcellular fractions of the tissues also showed continued ... | 1979 | 115629 |
| comparative aspects of blastocyst-endometrial interactions at implantation. | since the trophoblast-uterine adhesion is as nearly a universal phenomenon in implantation as can be found, an attempt was made to determine whether or not there was a reduction in cell surface glycoproteins in the rat, as can be observed in the ferret. neither colloidal iron nor cationized ferritin revealed the type of pattern anticipated for a localized reduction in surface negativity in the imprint of the blastocyst in the implantation chamber. the use of lectin-coated latex beads also proved ... | 1978 | 115657 |
| immunological interference with the maternal recognition of pregnancy in primates. | if chorionic gonadotropin is involved, as part of the luteotrophic stimulus, in the maternal recognition of pregnancy in primates, then immunization against the beta subunit of hcg should prevent a conception going beyond the length of the normal cycle. immunization against hcg-beta suppresses fertility in marmoset monkeys, baboons and rhesus monkeys, as long as the antibody titres remained high. as titres decline, however, female marmosets experience recurrent abortions interspersed with occasi ... | 1978 | 115658 |
| twenty-four-hour patterns in serum prolactin and cortisol after partial and complete isolation of the hypothalamic-pituitary unit in rhesus monkeys. | | 1979 | 115669 |
| the pattern of urinary excretion of corticosteroids in rhesus monkeys (macaca mulatta). | urinary total 17-oxogenic steroids (17-ogs), cortisol, cortisone, corticosterone, tetrahydrocortisol (thf), allo-tetrahydrocortisol (all-thf), tetrahydrocortisone (the), cortols and cortolones, were estimated by established methods in 30 female and 20 male rhesus monkeys. the pattern of the excretion of these steroids in this species was comparable with the human corticosteroids excretion, irrespective of sex difference. the results obtained from this investigation show that they could be used d ... | 1979 | 115672 |
| the velocity response of vestibular nucleus neurons during vestibular, visual, and combined angular acceleration. | in alert rhesus monkeys neuronal activity in the vestibular nuclei was measured during horizontal angular acceleration in darkness, acceleration of an optokinetic stimulus, and combined visual-vestibular stimulation. the working ranges for visual input velocity and acceleration extend up to 60 degrees/s and 5 degrees/s2. the corresponding working range for vestibular input acceleration is wider and time-dependent. during combined stimulation, that is acceleration of the monkey in the light, a li ... | 1979 | 115704 |
| acute decreases in serum prolactin concentrations caused by delta 9-tetrahydrocannabinol in nonhuman primates. | the acute effects of single injections of delta 9-tetrahydrocannabinol (thc) on serum prolactin (prl) concentrations were studied in oophorectomized female and intact adult male rhesus monkeys. some animals were challenged with thyrotropin-releasing hormone (trh) to determine whether thc influences pituitary responsiveness to releasing hormone. thc markedly suppresses serum prl concentrations in animals of both sexes. trh injections resulted in normal prl release when administered simultaneously ... | 1979 | 115723 |
| effects of delta 9-tetraphydrocannabinol administration on gonadal steroidogenic activity in vivo. | the effects of delta 9-tetrahydrocannabinol (thc) administration on gonadal steroidogenic activity in vivo were studied in two animal models: (1) luteal function of the rhesus monkey and (2) periovulatory steroid concentrations of rabbits treated with human chorionic gonadotropin (hcg). thc-treated monkeys demonstrated progesterone concentrations and luteal phase lengths which were not different from those in untreated controls. thc did not impair the normal pattern of response of the corpus lut ... | 1979 | 115724 |
| immune response after vaginal application of antigens in the rhesus monkey. | the immune response after vaginal application of antigens was investigated in six sexually mature female rhesus monkeys. two model antigens, i.e., lipopolysaccharide (lps) of salmonella typhosa and abortive type t-4 coliphages were applied with or without adjuvant. a plastic sponge used as the antigen carrier was introduced into the upper vagina and placed against the ectocervix. for primary immunization, each monkey received 18 vaginal antigen applications and 10 applications for each booster ... | 1979 | 115725 |
| characterization and biosynthesis of proteoglycans of corneal stroma from rhesus monkey. | the proteoglycans of the rhesus monkey corneal stroma were characterized by analyzing both radiolabeled proteoglycans synthesized by corneas in organ culture and native corneal proteoglycans obtained by large scale preparations. the analyses indicate that the proteoglycans synthesized in organ culture were similar to, if not identical with, their counterparts in the stroma although they are synthesized in different prportions in vitro than they acumulate in vivo. the corneal stroma contains two ... | 1979 | 115885 |
| projections of the cerebellar and dorsal column nuclei upon the inferior olive in the rhesus monkey: an autoradiographic study. | projections from the cerebellar and dorsal column nuclei to the inferior olive of the rhesus monkey were traced with anterograde autoradiographic methods. the cerebellar nuclei give rise to a massive projection which reaches the contralateral inferior olivary complex by way of the descending limb of the superior cerebellar peduncle. dentato-olivary fibers project exclusively upon the principal olivary nucleus (po) and observe a strict topography. the dorsal, lateral, and ventral dentate project ... | 1979 | 115909 |
| experimental delayed radiation necrosis of the brain. part 1: effect of early dexamethasone treatment. | the authors have designed an experiment to detect a hitherto unrecognized interaction between high doses of the glucocorticoid, dexamethasone, and brain irradiation. eighteen juvenile male rhesus monkeys received 1800 rads to the whole brain in 8.5 minutes. for 1 1/2 days before and 10 1/2 days after the irradiation, nine animals received approximately 2.9 mg/kg/day of dexamethasone intramuscularly in addition to irradiation, while the remaining nine animals served as the control group and recei ... | 1979 | 115970 |
| cryosurgery of major and minor salivary gland: a light microscopic evaluation in the rhesus monkey. | the minor salivary glands in the hard palate and the submandibular gland of the rhesus monkey were subjected to a liquid nitrogen, direct-spray, one-cycle freeze. a 4-min freeze in the temperature range of -40 degrees c to -60 degrees c was used. the extent of tissue destruction was determined at intervals up to 1 year. clinically relevant findings resulted and form the basis for subsequent studies by this group of investigators. | 1979 | 115981 |
| pharmacologic characterization of isolated rhesus monkey bronchial smooth muscle. | | 1979 | 115993 |
| the effects of cooling globus pallidus on manual tracking in trained rhesus monkeys [proceedings]. | | 1979 | 115995 |
| establishing a free-ranging breeding colony of rhesus monkeys. part i. | the caribbean primate research center recently contracted with the food and drug administration to establish a free-ranging island breeding colony of rhesus monkeys. the goal of the program is to produce 600 to 800 offspring yearly from 1,000 breeding age females. the initial colony stock will consist of approximately 360 animals from an existing colony that was established on an island off the southwestern coast of puerto rico in 1961. expansion of the colony will be accomplished by the purchas ... | 1979 | 116000 |
| clinical appearance of the hyaloid artery system in the newborn rhesus monkey. | fifteen healthy newborn rhesus monkeys (macaca mulatta) were given funduscopic examinations as part of a screening process before utilization in a research project. the hyaloid vasculature, a system that supplies blood to the embryonic ocular structures, was observed in each subject and was noted to regress clinically at two to three weeks of age. although the phenomenon has been described morphologically in the literature, its clinical appearance has not been illustrated for the primate clinici ... | 1979 | 116004 |
| clinical utilization of mechanical sutures for intestinal anastomosis in macaca mulatta. | using three mechanical stapling instruments that employ stainless steel wire staples, a mann-bollman fistula was created on the terminal ileum in 27 rhesus monkeys (macaca mulatta). two functional end-to-end anastomoses were accomplished and an ileostium constructed. staples of various sizes were used; it was found that pediatric-sized staples were necessary for the intestinal tissue of these primates. six months after surgery, microscopic examination revealed encapsulation of the staples by gra ... | 1979 | 116072 |
| the effects of methamphetamine on fine motor control in rhesus monkeys. | six rhesus monkeys were trained to extend their arms through a tube to press a lever with between 25 and 40 g of force for 3 or 5 sec. responding was maintained by the delivery of 1.5 cc of water. stimulus lights indicated whether the exerted force was below 25 g. between 25 and 40 g (i.e., correct) or above 40 g. sessions were terminated after 50 water deliveries or 30 min had elapsed. performance was well-maintained in all monkeys. allowing the animals access to water prior to the session had ... | 1979 | 116246 |
| effects of an enkephalin analog on complex learning in the rhesus monkey. | facilitation of the learning of a discrimination reversal task for a reward of food was found in rhesus monkeys after subcutaneous administration of a potent pentafluorinated enkephalin analog. (d-ala2)-f5-phe4-enkephalin-nh2. general activity, short-term memory, startle, and analgesia, however, were not significantly affected. in a within-subject design, each of 6 monkeys (3 males and 3 females) received each of 5 doses of the enkephalin analog (0.1, 1, 10, 100, and 1,000 microgram/kg). one dai ... | 1979 | 116247 |
| behavioral effects of stimulating positive reward sites in the central tegmentum of rhesus monkeys. | | 1979 | 116261 |
| cocaine, d-amphetamine, and pentobarbital effects on responding maintained by food or cocaine in rhesus monkeys. | the effects of im injections of cocaine, d-amphetamine, and pentobarbital were studied in rhesus monkeys whose lever-press responding was maintained under a second-order fixed-interval, fixed ratio schedule of reinforcement. within each session, fixed-interval components, ending with the iv injection of 30 microgram/kg cocaine (one group of monkeys) or the delivery of a 300 mg food pellet (second group of monkeys), alternated with fixed-interval components ending without an injection of cocaine ... | 1979 | 116268 |
| brain blood flow and metabolism after global ischemia and post-insult thiopental therapy in monkeys. | we measured total and regional cerebral blood flow (cbf, rcbf) and cerebral metabolic rate (cmr) of oxygen (o2), glucose (g), and lactate (l) levels for 4 h after 16 min global brain ischemia in rhesus monkeys with and without post-insult thiopental therapy. eleven monkeys weighing 4-5 kg anesthetized with 1 percent halothane, 66 percent nitrous oxide and 33 percent oxygen, were subjected to 16 min global brain ischemia by a combination of trimethaphan hypotension (to a mean arterial pressure of ... | 1979 | 116395 |
| effects of biorhythms on blood flow distribution in the pregnant uterus (macaca mulatta). | ten rhesus monkeys were studied between 143 and 161 days of gestation. the unanesthetized animals were confined to restraining chairs and maintained in a controlled environment with continuous monitoring of spontaneous uterine dynamics. forty-five determinations of blood flow distribution were made using radionuclide-labeled microspheres. the microsphere injections confirmed a circadian pattern of uterine blood flow. these biorhythms are related to alterations in distribution of blood flow to pl ... | 1979 | 116548 |
| the development of a "high volume tissue schizonticidal drug screen" based upon mortality of mice inoculated with sporozoites of plasmodium berghei. | a biological test system has been developed to assess the prophylactic activity of compounds against sporozoite-induced plasmodium berghei malaria in mice. the procedure was designed to serve as the foundation of an effort to develop tissue schizonticidal drugs in a manner parallel to that of a previous system employed in the u.s. arym antimalarial drug development program to screen compounds for blood schizonticidal activity. in tests with 35 known antimalarial compounds, the new screen was fou ... | 1979 | 116556 |
| plasmodium fragile and macaca mulatta monkeys as a model system for the study of malaria vaccines. | pladmodium fragile and the macaca mulatta monkey are presented as a model system for the study of malarial vaccines. four animals were immunized with culture-grown p. fragile merozoites and subsequently challenged with culture-produced parasites. one animal failed to develop a detectable parasitemia following primary challenge. two other immunized animals had primary infections which were short-term. the parasitemias in these three monkeys following secondary challenge were short-term and the im ... | 1979 | 116557 |
| immunogenetic studies of rhesus monkeys. 6. absence of the human xga blood group on rhesus erythrocytes. | it was not possible to demonstrate xga on the erythrocytes of any of 140 rhesus monkeys of both sexes tested with human antiserum rendered specific for xga by absorption. | 1979 | 116572 |
| opsonization, phagocytosis and killing of streptococcus mutans by polymorphonuclear leukocytes, in relation to dental caries in the rhesus monkey (macaca mulatta). | | 1979 | 116635 |
| 360 degrees prophylactic cryoretinopexy. a clinical and experimental study. | complications occurred after 360 degrees prophylactic cryoretinopexy in three of six eyes in which fellow eyes had previously developed aphakic retinal detachment. two of the six prophylactically treated eyes developed retinal detachment in advance of anticipated cataract surgery, and a third developed vitreitis and progressive preretinal membrane formation after uncomplicated cataract extraction. in an experiment study with rhesus monkeys, preretinal membrane formation was produced by administe ... | 1979 | 116636 |
| a direct inferior parietal lobule projection to the presubiculum in the rhesus monkey. | | 1979 | 116714 |
| paired stimulation of the frontal eye fields and the euperior colliculus of the rhesus monkey. | | 1979 | 116715 |
| laminar origins and terminations of cortical connections of the occipital lobe in the rhesus monkey. | cortical connections within the occipital lobe (areas 17, 18 and 19) of the rhesus monkey are investigated with the autoradiographic and horseradish peroxidase procedures. two efferent systems, each with a specific laminar organization, are observed. (1) rostrally directed connections, from area 17 to 18, area 18 to 19 and area 19 to the inferotemporal region (area te), originate from neurons in layer iiic (and, in area 19, from a small complement of neurons in layer va), and terminate in and ar ... | 1979 | 116716 |
| taurolithocholic acid and chlorpromazine cholestasis in the rhesus monkey. | | 1979 | 116762 |
| treatment of rhesus monkeys (macaca mulatta) with intravaginal rings impregnated with either progesterone or norethisterone. | the effects of both progesterone- and norethisterone-loaded intravaginal rings were investigated in twenty-five rhesus monkeys for 52 weeks. the intravaginal rings were designed to provide a sustained release of either the human dosage level of the hormone or ten times this level. untreated placebo rings were used for control purposes. the devices were well retained. with the exception of increased plasma fibrinogen levels in animals treated with norethisterone, no marked differences in either l ... | 1979 | 116799 |
| the influence of vagotomy on bile kinetics in the rhesus monkey. | an increased incidence of gallstones has been reported following truncal vagotomy and gastric drainage but never conclusively proven. in the rhesus monkey, bile composition and flow is similar to man. a model of biliary drainage was established which permits continuous monitoring of bile kinetics. following truncal vagotomy and pyloroplasty, a significant fall in the bile acid concentration was observed, accompanied by a rise in cholesterol concentration. this resulted in an overall rise in chol ... | 1979 | 116853 |
| immunofluorescent and immunoelectron microscopic demonstration of primate heart muscle antigens cross-reactive with streptococcus pyogenes. | the presence of antigens in heart muscles cross-reactive with antibodies against streptococcus pyogenes were examined in heart samples of seven primate species (chimpanzee, rhesus macaque, stump-tailed macaque, hamadryas baboon, capuchin monkey, green monkey and patas monkey). cross-reactive antigens were localized by means of the indirect immunofluorescent technique in nearly all samples tested. the fluorescence pattern was the same as found in the heart muscle of other mammals. using the indir ... | 1979 | 116866 |
| atherosclerotic plaque regression in rhesus monkeys induced by bile acid sequestrant. | | 1979 | 116868 |
| in vitro metabolism of tetrahydrocannabinol by rhesus monkey liver and human liver. | | 1978 | 116879 |
| reproduction in rhesus monkeys chronically exposed to delta-9-tetrahydrocannabinol. | | 1978 | 116881 |
| social behavior of rhesus monkeys chronically exposed to moderate amounts of delta-9-tetrahydrocannabinol. | | 1978 | 116882 |
| chronic hyperinsulinemia in the fetal rhesus monkey: effects on fetal growth and composition. | | 1979 | 116897 |
| rhesus monkey aqueous humor composition and a primate ocular perfusate. | the composition of rhesus monkey aqueous humor has been studied in large-volume, pooled samples. replicate determinations of the concentrations of a number of constituents have been carried out for both aqueous humor and serum from large veins by means of automatic analyzing equipment. since aqueous humor has been obtained by anterior chamber paracentesis, it is a mixture of anterior and posterior chamber aqueous. when compared to serum, the pooled aqueous contains an excess of chloride, bicarb ... | 1979 | 116968 |
| porous titanium endosseous dental implants in rhesus monkeys: microradiography and histological evaluation. | artificial tooth roots with porous surface coatings were fabricated by sintering spherical powder of titanium alloy to solid cylindrical cores. the tooth roots were implanted subgingivally in healed mandibular premolar extraction sites of fifteen rhesus monkeys. supracrestal abutments were screwed into pretapped holes in the superior aspect of the primary subgingival stage four to eight weeks after implantation of the root. clinical evaluations were performed monthly. ten animals were sacrificed ... | 1979 | 117007 |
| in vivo enhancement of dengue virus infection in rhesus monkeys by passively transferred antibody. | five pairs of juvenile, dengue virus-susceptible rhesus monkeys were given normal or dengue-immune human cord-blood serum injected intravenously to a final dilution of 1:300. the pool of immune human cord-blood serum had a titer of antibody to dengue type 2 virus (d2v) of 1:140 in the plaque-reduction neutralization test and a titer of human monocyte infection enhancement of greater than 1:2,000,000. fifteen minutes after inoculation of serum, animals were infected with d2v (strain no. 16681). d ... | 1979 | 117061 |
| induction of allergic encephalomyelitis in rhesus monkeys treated with anti monkey thymocyte sera. | treatment with rabbit anti-moneky thymus cell sera whether limited (3 days) or extensive (15 days), did not alter the development of experimental allergic encephalomyelitis (eae) in rhesus monkeys challenged with myelin basic protein or central nervous system tissue (cns) when compared to similarly challenged control monkeys treated with normal rabbit serum. no consistent difference in disease incidence or intensity as measured by incubation period, neurologic signs or cns pathology was observed ... | 1979 | 117083 |
| infection and transmission studies with plasmodium simiovale in the macaca mulatta monkey. | six different anophelines--anopheles freeborni, an. b. balabacensis, an. maculatus, an. stephensi, an. atroparvus, and an. quadrimaculatus--were shown to be susceptible to infection with plasmodium simiovale when fed upon splenectomized macaca mulatta monkeys between the 1st and 26th days of patent parasitemia. transmission was obtained via the bites of an. b. balabacensis and an. maculatus mosquitoes. prepatent periods in m. mulatta monkeys following sporozoite inoculation ranged from 11 to 20 ... | 1979 | 117087 |