| bacteriophages of bacteroides. | sixty-eight bacteriophages specific for nine species (dna homology groups) of bacteroides were isolated from sewage. four distinct morphological types were isolated, three of which had not previously been described. attempts to use these phages to transduce bacteroides fragilis were unsuccessful. a total of 91 phage-susceptible strains of bacteroides were used with these phages in a study of the feasibility of developing a scheme for identification of bacteroides species. blind trials were perfo ... | 1979 | 398578 |
| acute pelvic inflammatory disease. | | 1977 | 412258 |
| simple method for detection of penicillinase-producing neisseria gonorrhoeae. | a simple, reliable, and economical method for detection of penicillinase-producing neisseria gonorrhoeae using a penicillin disk and a penicillin-sensitive organism is described. | 1978 | 415067 |
| surgical treatment of valvular heart disease. | | 1978 | 415632 |
| cefoxitin and cephamycins: microbiological studies. | the cephamycins are a family of beta-lactam antibiotics that are produced by actinomycetes and are structurally similar to the cephalosporins. they are characterized by the presence of a 7-alpha-methoxyl group, which confers unusually high resistance to beta-lactamases. cefoxitin, the first semisynthetic cephamycin, is resistant to almost all beta-lactamases. cefoxitin retains the 3-carbamoyl group of cephamycin c and thus has excellent metabolic stability. cefoxitin is bactericidal and almost d ... | 1979 | 400941 |
| colonization resistance against potentially pathogenic bacteria in hexaflora-associated gnotobiotic mice. | a study of colonization resistance against potentially pathogenic bacteria (escherichia coli and pseudomonas aeruginosa) was conducted in hexaflora-associated gnotobiotic mice. groups of germfree akr mice were swabbed with five bacterial and a single gastrointestinal yeast species: streptococcus faecalis. lactobacillus brevis. staphylococcus epidermidis, enterobacter aerogenes, bacteroides fragilis var. vulgatus, and torulopsis sp. all species became established in the gut in 8 weeks. later thes ... | 1978 | 417787 |
| treatment of anaerobic infections with metronidazole. | metronidazole (flagl), a compound widely used in man with minimal side-effects, has been used in the treatment of anaerobic infections caused by bacteroides fragilis and other bacteroides species. seven patients were treated and all were restored to full health. four of them did not respond to lincomycin or clindamycin which so far have been the drugs of choice against anaerobic infections. the reasons for the good results during metronidazole therapy such as the good penetration through the blo ... | 1979 | 419371 |
| effect of some bacterial products on platelet electrophoretic mobility (pem). | bacterial lps, used in our experiments, are able to decrease pem at concentration of 100 microgram/ml after incubation with 1 x 10(7) platelets/ml for 30 min at 37 degrees c. such effect is statistically significant for bacteroides fragilis lps, s. enteritidis and s. typhi. e. coli lps 026:b6 w and e. coli 055:b5 w are not effective at all, s. minnesota (incomplete) lps 595 and 345 free of 0-polysaccharide and partially lacking core in their molecule did not influence pem, while s. minnesota lps ... | 1977 | 410424 |
| anterograde transneuronal degeneration in the limbic system: clinical-anatomic correlation. | a 64-year-old man with diffuse atherosclerosis developed an organic mental syndrome, followed by hypothalamic symptoms. autopsy showed an old large cystic infarct involving the left temporal lobe including the hippocampus, and atrophy of the ipsilateral fornix, mammillary body, hypothalamus, mammillothalamic tract, and the anterior thalamic nucleus. the clinical deterioration and pathologic findings may be explained by anterograde transneuronal degeneration within the limbic system following the ... | 1977 | 412120 |
| septic induced acute gastric erosions: the role of cimetidine. | | 1978 | 417217 |
| studies of the antitumor action of 5-fluorouracil (fu). | | 1979 | 420946 |
| factors contributing to resistance to beta-lactam antibiotics in bacteroides fragilis. | fifteen strains of bacteroides fragilis, five highly resistant, five moderately resistant, and five susceptible to benzylpenicillin and cephaloridine, were tested for beta-lactamase production. in the highly resistant and the moderately resistant groups of strains, a correlation between formation of beta-lactamase and minimal inhibitory concentrations was demonstrated. in the presence of the beta-lactamase inhibitors clavulanic acid and cp-45,899 at concentrations of 1 mug/ml, the susceptibility ... | 1979 | 426517 |
| hr 756, a new cephalosporin active against gram-positive and gram-negative aerobic and anaerobic bacteria. | the in vitro activity of hr 756, 7-[2-(2-amino-4-thiazolyl)-2-(z)-(methoximino)acetamido] cephalosporanic acid, was investigated against 659 isolates. hr 756 inhibited neisseria and haemophilus species at concentrations similar to those needed with ampicillin. it inhibited beta-lactamase-producing n. gonorrhoeae and h. influenzae. hr 756 was the most active compound tested against members of the enterobacteriaceae, inhibiting most isolates of escherichia coli, klebsiella pneumoniae, proteus mira ... | 1979 | 426518 |
| n,n-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells. | human colon carcinoma cell lines established in this laboratory were treated in vitro with n,n-dimethylformamide. this polar solvent caused morphological changes in the cells as well as alterations in their growth properties. untreated cells had cloning efficiencies of up to 77% in soft agar; treatment with n,n-dimethylformamide resulted in a complete loss of clonogenicity in semisolid medium. growth in the presence of the polar solvent also effected a marked reduction in the tumorigenicity of t ... | 1979 | 427742 |
| incidence and pathological features of spontaneous tumors in athymic nude mice. | systematic observation of 1141 nude mice (swiss background [corrected] strain) that received human tumor transplants revealed 24 spontaneous tumors, 18 of lymphoreticular origin and 6 pulmonary adenomas. spontaneous tumors were seen at an average age of 9.1 months, and 22 of the tumors were seen only in that fraction of our group (324 mice) surviving for 5 months or more (22 of 324 x 100 = 6.8%). transplantation of these tumors to other nude mice was successful in three of five cases. mice trans ... | 1979 | 427772 |
| lipopolysaccharides from pseudomonas maltophilia: structural studies of the side-chain polysaccharide from strain n.c.t.c. 10257. | a lipopolysaccharide has been isolated from pseudomonas maltophilia n.c.t.c. 10257. monosaccharide components identified were l-rhamnose, 3-o-methyl-l-xylose, l-xylose, d-glucose, d-mannose, d-galacturonic acid, 2-amino-2-deoxy-galactose, 2-amino-2-deoxyglucose, and a 3-deoxy-2-octulosonic acid. heptose was absent. in this and other respects, the lipopolysaccharide resembles the corresponding products from xanthomonas species. mild hydrolysis of the lipopolysaccharide with acid, followed by chro ... | 1979 | 427832 |
| occupational chronic exposure to organic solvents. vii. metabolism of toluene in man. | | 1979 | 429070 |
| histochemical and atomic absorption demonstration of trace metal mobilization in the central nervous system and liver of the rat. | histochemical and atomic absorption spectrophotometric analysis of trace metal mobilization caused by the action of ethanol in the central nervous system (cns) and liver of the rat is described. histochemically it has been shown that in all neurons examined (motoneurons, pyramidal and purkinje cells) the trace metals (mainly zn2+ and cu2+) are mobilized. most of the stained materials disappear from the perikaryon of the purkinje cells, while in both the motoneurons and the pyramidal cells the tr ... | 1979 | 429206 |
| the link proteins as specific components of cartilage proteoglycan aggregates in vivo. associative extraction of proteoglycan aggregate from swarm rat chondrosarcoma. | | 1979 | 429293 |
| activation of membrane-bound glucosylceramide: beta-glucosidase in fibroblasts cultured from normal and glucosylceramidotic human skin. | | 1979 | 429368 |
| specific cytosol receptors for 1,25-dihydroxyvitamin d3 in human intestine. | human intestine is shown to contain a specific, high affinity cytosol receptor or binding protein for 1,25-(oh)2-vitamin d3 [1,25 (oh)2d3]. this receptor is a protein which sediments at 3.5s on sucrose gradients containing 0.3 m kcl. the receptor binds 1,25 (oh)2d3 with a kd of approximately 2 x 10(-10) m at 4 degrees c. competition binding studies using structural analogs of 1,25 (oh)2d3 indicate that the relative specificity of the receptor is 1,25 (oh)2d3 greater than 1,24r,25(oh)3d3 greater ... | 1979 | 429514 |
| decreased heat-labile opsonic activity and complement levels associated with evidence of c3 breakdown products in infected pleural effusions. | heat-labile opsonic activity was measured simultaneously in serum and pleural fluid of patients with transudates, infectious exudates (with positive or negative bacterial culture) and neoplastic exudates, using two different complement-dependent phagocytic tests: the killing of staphylococcus aureus wood 46 variant strain (k50 opsonic titers) and the assessment of ingestion rate of endotoxin-coated paraffin particles (oil red 0 uptake test). k50 opsonic titers were lower in culture-positive pleu ... | 1979 | 429556 |
| simulated hyperglycemic hyperosmolar syndrome. impaired insulin and epinephrine effects upon lipolysis in the isolated rat fat cell. | these investigations were designed to evaluate the effect of excess glucose and sodium chloride on lipolysis in the isolated adipocyte under normal and modelled pathological conditions simulating the hyperglycemic hyperosmolar syndrome. isolated rat fat cells were incubated in the presence of various combinations of sodium chloride, glucose, epinephrine, and insulin. lipolysis was measured as glycerol and free fatty acid release, and total medium osmolarity as milliosmoles per liter by freezing ... | 1979 | 429561 |
| preservation of binocularity after monocular deprivation in the striate cortex of kittens treated with 6-hydroxydopamine. | the results of single unit recordings from area 17 of monocularly deprived kittens were compared with similar ones from littermates who had been monocularly lid-sutured for the same period of time, but who had in addition been given intraventricular injections of 6-hydroxydopamine (6-ohda) to deplete brain catecholamines. this visual cortices of all catecholamine-depleted kittens showed high proportions of binocular neurons, in contrast to the control group, a majority of whose visual cortical n ... | 1979 | 429612 |
| behavioral and electrophysiological effects of unilateral optic tract section in ordinary and siamese cats. | in ordinary cats, section of one optic tract produced a complete contralateral hemianopsia in both eyes. single-unit recordings showed a normal representation of the contralateral nasal retina and ipsilateral temporal retina in the sc on the side of the intact optic tract. in addition, in the rostral portion of this sc there was a representation of a small portion of the contralateral temporal retina. this portion was apposed to the vertical meridian and its width was at most 6 degrees. in the a ... | 1979 | 429613 |
| evidence of csf enhancement in the spinal subarachnoid space after intravenous contrast medium administration: is intravenous computer assisted myelography possible? | following intravenous injection of iodinated contrast medium, peripheral enhancement of the area inside the spinal canal, is frequently observed by computed tomography. this may be due, at least in part, to enhancement of the cerebrospinal fluid in the spinal subarachnoid space. our preliminary observations in human patients and in animal experiments are reported. the goal of intravenous computer assisted myelography is worth pursuing. | 1979 | 429634 |
| metabolism of atrazine by the soluble fraction (105000g) from chicken liver homogenates. | | 1979 | 429685 |
| effect of vegetable juices and milk on alkylating activity of n-methyl-n-nitrosourea. | | 1979 | 429698 |
| [a biomechanical study on the fracture treatment--intravital measurement of the strain on an intramedullary nail in the healing process of the femoral fracture in goats (author's transl)]. | there have been many biomechanical studies throughout the world on the fracture treatment. however, only a few were performed under intravital condition. the purpose of the present study is to measure the successive strength changes of the callus after a fracture, in vivo in an animal. method: specifically designed küntscher nails were made to meet the anterior convexity and the size of the medullary canal of the femora of goats. three self-temperature-compensating semi-conductor strain-gauges w ... | 1979 | 429823 |
| effects of dialyzable leukocyte extracts with transfer factor activity on leukocyte migration in vitro. 1. antigen-dependent inhibition and antigen-independent inhibition and enhancement of migration. | the effects of dle containing tfd activity from immune human donors on pbl, obtained from individuals nonresponsive to either ppd or cocci antigen, were evaluated in vitro by the agarose lml technique. several different preparations of dle were employed to evaluate the specificity and reproducibility of the effects: (1) from donors skin test positive to ppd but negative to cocci, (2) from donors skin test negative to ppd but positive to cocci, (3) from donors skin test positive to both antigens, ... | 1979 | 429876 |
| amino acid content of rat renal cortex and the response to in vitro incubation. | the concentration of aspartic acid, threonine, serine, glycine, and alanine is significantly higher in newborn rat renal cortex than in the adult tissue, while phenylalanine and histidine are higher in the adult. when adult cortical slices are placed in bicarbonate buffer at room temperature for 20 min there is a 30-60% decrease in the levels of all amino acids except for lysine, which is slightly higher, and methionine and serine, which do not change. under the same conditions, newborn cortical ... | 1979 | 434215 |
| [bacteroides fragilis meningitis and bacteremia. report of a case with otogenic focus and a brief review]. | | 1979 | 425199 |
| comparison of the membrane composition of spiroplasma citri and the corn stunt spiroplasma. | components of membranes isolated from spiroplasma citri and corn stunt spiroplasma grown at 28 degrees c were analyzed. on a protein basis, lipid phosphorus was lower and cholesterol was higher in s. citri. only minor differences between the two species were found in fatty acid composition, reduced nicotinamide adenine dinucleotide diaphorase, and adenosine triphosphatase. | 1979 | 422510 |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 15-1979. | | 1979 | 423921 |
| antimicrobial activity of antituberculosis agents against anaerobic bacteria. | anaerobic infections may coexist with tuberculosis, and can be mistaken for one another. the effect of therapy with antituberculosis chemotherapeutic agents against anaerobic bacteria (with the exception of rifampin) is unknown. we therefore examined the in vitro efficacy of certain commonly used antituberculosis agents (rifampin, isoniazid, and ethambutol) against 370 strains of anaerobic bacteria, including 86 isolates of bacteroides fragilis. rifampin at a concentration of 2 microgram/ml inhi ... | 1979 | 436485 |
| plasmid-mediated, transferable resistance to clindamycin and erythromycin in bacteroides fragilis. | a clindamycin- and erythromycin-resistant strain of bacteroides fragilis, tmp10, that had been isolated from a blood culture transferred its drug resistance in a millipore mating procedure to another strain of b. fragilis, tm2000, and to a strain of bacteroides thetaiotaomicron. donor strain tmp10 contained numerous species of extrachromosomal dna ranging from approximately 2 x 10(6) to 20 x 10(6) daltons in molecular weight, as revealed by agarose gel electrophoresis. clindamycin- and erythromy ... | 1979 | 438530 |
| metronidazole therapy of anaerobic bacteremia, meningitis, and brain abscess. | four patients with bacteroides fragilis bacteremia, one patient with a brain abscess due to bacteroides species, fusobacterium naviforme, and peptostreptococcus species, and an infant with bacteroides species ventriculitis and meningitis were treated with metronidazole. in all cases the anaerobic pathogens were eradicated. five of the six patients recovered. one patient with leukemia in whom b fragilis bacteremia was eradicated by metronidazole treatment subsequently died of pseudomonas aerugino ... | 1979 | 434970 |
| encapsulated strains of bacteroides fragilis in clinical specimens. | studies were made of the presence of capsules in 294 strains of the bacteroides fragilis group of bacteria isolated from clinical infections and in 30 strains from the fecal flora using the indian ink and ruthenium red staining methods. a total of 77% of the b. fragilis strains were encapsulated; higher figures were observed in isolates from blood and wound infections. of the b. ovatus, b. distasonis, b. vulgatus, b. uniformis, and b. thetaiotaomicron isolates from clinical infections, 17% were ... | 1979 | 440201 |
| growth yields and fermentation balance of bacteroides fragilis cultured in glucose-enriched medium. | bacteroides fragilis is an obligate anaerobic bacterium classified with the gram-negative, non-sporeforming bacilli and is the bacteroides species most frequently isolated from human infections. in the present study, experiments were designed to investigate growth characteristics of b. fragilis in a complex medium. in a minimal defined medium, which was employed for comparison purposes, b. fragilis grew with a generation time of 2 h. growth of the organism in glucose-enriched medium used in the ... | 1979 | 438119 |
| superoxide dismutase and o2 lethality in bacteroides fragilis. | exposure of midlog bacteroides fragils (vpi 2393) to 2% o2-98% n2 caused a three- to fivefold increase in superoxide dismutase specific activity within the cells. the increase in specific activity was completed within 90 min after exposure to oxygen and was dependent upon protein synthesis. cells containing the higher superoxide dismutase level were more resistant to the effects of 5 atm of oxygen tension than were cells containing the lower level of superoxide dismutase but were equally resista ... | 1979 | 438129 |
| [bacteriological and clinical studies on metronidazole in bacteroides fragilis infections (author's transl)]. | the antimicrobial activity of 24 bacteroides fragilis, 13 bacteroides thetaiotaomicron and 5 bacteroides vulgatus, all of which were recent clinical isolates, was determined by the agar dilution technique. these three species had similar susceptibility patterns, but the b. thetaiotaomicron strains were generally less susceptible than the b. fragilis strains. clindamycin was very active against 81% of the bacteroides strains at 3.1 mcg/ml of less while 21% of the bacteroides strains had mics of 1 ... | 1979 | 439390 |
| anaerobic bacteremia following suprapubic bladder aspiration. | | 1979 | 448482 |
| aerobic and anaerobic bacterial flora of the maternal cervix and newborn gastric fluid and conjunctiva: a prospective study. | aerobic and anaerobic cultures were performed on cervical swabs from 35 mothers and their newborn infants' gastric aspirates and conjunctival sacs. four hundred seventy-nine isolates were obtained; 287 were aerobes and 192 were anaerobes. the cervical and gastric cultures overall yielded a similar flora, but this was not always the case when one compared mothers with their own newborn infants. the conjunctival cultures yielded about half of the number of bacteria per specimen that the gastric co ... | 1979 | 440845 |
| common regulatory mechanism of expression and conjugative ability of a tetracycline resistance plasmid in bacteroides fragilis. | | 1979 | 450069 |
| erythromycin for anaerobic pleuropulmonary and soft-tissue infections. | erythromycin has been reported to be active in vitro against most anaerobic bacteria. we found it effective in treating 14 of 17 patients with mild to moderately severe anaerobic or mixed aerobic/anaerobic pleuropulmonary of soft-tissue infections when adjunctive measures (eg, drainage, débridement, and the use of additional antibiotics to treat important aerobic pathogens) were employed. erythromycin offers a reasonable therapeutic alternative to penicillin in the treatment of a penicillin-alle ... | 1979 | 448959 |
| transferable lincosamide-macrolide resistance in bacteroides. | | 1979 | 451051 |
| control of experimental breast cancer by antioestrogenic therapies [proceedings]. | | 1979 | 444379 |
| liposome-incorporated corticosteroids: i. the interaction of liposomal cortisol palmitate with inflammatory synovial membrane. | cortisol palmitate-containing liposomes were stable in rheumatoid synovial fluid at 37 degrees. two hours after the intra-articular injection of such liposomes into experimentally arthritic rabbits relatively high proportions of the steroid and lecithin components were recovered from the synovialis. the level of cortisol in the tissue at this time was inversely related to the chronicity of the inflammation. it was found also that the degree and duration of the anti-inflammatory activity of the l ... | 1979 | 444417 |
| comparison of anaerobic susceptibility results obtained by different methods. | susceptibility tests using 7 antimicrobial agents (carbenicillin, chloramphenicol, clindamycin, penicillin, cephalothin, metronidazole, and tetracycline) were run against 35 anaerobes including bacteroides fragilis (17), other gram-negative bacilli (7), clostridia (5), peptococci (4), and eubacteria (2). results in triplicate obtained by the microbroth dilution method and the aerobic modification of the broth disk method were compared with those obtained with an agar dilution method using wilkin ... | 1979 | 464560 |
| susceptibility of isolates of bacteroides to the bactericidal activity of normal human serum. | seventy-one strains of species from the bacteroides fragilis group, including 46 isolates of b. fragilis, were tested for susceptibility to the bactericidal effect of serum from healthy subjects. twenty-seven (38%) of the isolates were killed by serum. isolates from feces were significantly more sensitive to serum than were isolates from patients with clinical infections. killing of bacteria required heat-labile serum components and was an exponential function of serum concentration. among the v ... | 1979 | 458196 |
| isolation and properties of metronidazole-resistant mutants of bacteroides fragilis. | metronidazole-resistant mutants of bacteroides fragilis, isolated after mutagenesis, had diminished ability to take up and metabolize the drug. all the metronidazole-resistant strains had depressed levels of pyruvate dehydrogenase compared with parent cultures. their end products of glucose metabolism also differed from normal b. fragilis products and were consistent with deficiencies in pyruvate dehydrogenase activity. | 1979 | 475371 |
| cefoxitin: single-agent treatment of mixed aerobic-anaerobic pelvic infections. | cefoxitin (mefoxin), a new semisynthetic cephamycin antibiotic, resistant to degradation by beta-lactamase enzymes produced by bacteria. in vitro, cefoxitin is active against virtually all clinically important gram-negative facultative bacteria other than pseudomonas and enterobacter spp., gram-positive aerobic bacteria other than the enterococcus, and clinically important anaerobic organisms, including bacteroides fragilis. this broad antibacterial spectrum suggested that cefoxitin might be an ... | 1979 | 460753 |
| the kidney in health and disease: x. cns manifestations of disordered salt and water balance. | | 1979 | 478503 |
| occurrence of free ceramides in bacteroides fragilis nctc 9343. | the occurrence of free ceramides at high concentrations was demonstrated in the chloroform-methanol extractable lipids of bacteroides fragilis nctc 9343. the long-chain bases were isolated from the free ceramides and identified as branched and normal saturated dihydroxy bases with carbon chains consisting of 17, 18, and 19 atoms. the major fatty acid was 3-hydroxy 15-methylhexadecanoic acid. the major molecular species of the ceramides were identified by gas chromatography-mass spectrometry and ... | 1979 | 479134 |
| survival of anaerobic bacteria in common laboratory diluents. | the survival of six species of anaerobic bacteria was studied in simple or commercially available diluents. bacteroides fragilis and fusobacterium nucleatum showed excellent survival in all diluents including distilled water. fusobacterium mortiferum survived well in all diluents except water and water supplemented with 0.1% gelatain. clostridium perfringens survived best in phosphate-buffered saline with gelatin. peptococcus asaccharolyticus required gelatin added to the basic diluent, and stre ... | 1979 | 479359 |
| in vitro activity of sodium fusidate against anaerobic bacteria. | the microtiter broth dilution method was employed to determine the in vitro susceptibility of 525 recent clinical isolates of anaerobic bacteria to sodium fusidate. the minimal inhibitory concentrations of sodium fusidate ranged from </=0.06 to 1.0 mug/ml for 155 strains of anaerobic gram-positive rods and 130 strains of anaerobic gram-positive cocci. minimal inhibitory concentrations ranging from </=0.06 to 32 mug/ml were observed for 240 strains of anaerobic gram-negative rods. among the latte ... | 1979 | 485124 |
| [anaerobic septicemia in obstetrics and gynecology]. | | 1979 | 488824 |
| bacterial colonization, tracheobronchitis, and pneumonia following tracheostomy and long-term intubation in pediatric patients. | serial tracheal cultures for aerobic and anaerobic bacteria were obtained from 27 pediatric patients during one year of follow-up. the patients had required tracheostomy and prolonged intubation for periods ranging from 3 to 12 months (average, 7 1/2 months). cultures of tracheal aspirates yielded 1,508 isolates of pathogenic aerobic (969 isolates) and anaerobic (539 isolates) bacteria. the most frequent aerobic isolates were streptococcus pneumoniae and staphylococcus aureus. the predominant an ... | 1979 | 477429 |
| anaerobic bacteria in late infections following orthopedic surgery. | twelve patients with late anaerobic infection following hip or knee arthroplasty or tibia osteosynthesis are presented. peptococci (peptococcus asaccharolyticus, p. magnus, p. prevotii) and peptostreptococci (peptostreptococcus micros, p. anaerobius, p. parvulus) were present in nine of the cases. anaerobic gram-positive or -negative rods were found in three cases (propionibacterium acnes, actinomyces israelii, and bacteroides fragilis). antibodies against the isolated bacteria were detected in ... | 1979 | 492071 |
| microbiology of superficial and deep tissues in infected diabetic gangrene. | in the current study, it is shown that, in the lesions of diabetic gangrene, there are usually mixed flora of two or more organisms. the organisms isolated from the presenting lesion may only partially reflect the organisms found in the deep tissues. of the 58 cultures from the deep tissues, 11 of the isolates were anaerobes, but those anaerobes were never isolated as a pure culture. bacterial synergism probably plays a role in infected diabetic gangrene. maximizing the reduction of systemic inf ... | 1979 | 462355 |
| in vitro activity of mezlocillin and its related compounds against aerobic and anaerobic bacteria. | a total of 900 clinical isolates of aerobic (462 isolates) and anaerobic (438 isolates) bacteria were tested against mezlocillin in comparison with other penicillins, and the aerobes were also tested against cephalothin, cefoxitin, and cefamandole. among penicillins, mezlocillin was the most effective against escherichia coli, klebsiella pneumoniae, salmonella species, pseudomonas aeruginosa, and bacteroides fragilis. mezlocillin was more effective than cephalothin against klebsiella pneumoniae. | 1979 | 464578 |
| the inhibitory material in extracts from the bovine retractor penis muscle is not an adenine nucleotide. | methods are described for the removal of adenosine or purine nucleotides from extracts of bovine retractor penis muscle (brp). these methods did not interfere with the biological test preparations. removal of adenosine and purine nucleotides by these methods did not modify the inhibitory action of the extract on the brp. the effect of the extract on the brp resembles that of inhibitory nerve stimulation. if the inhibitory substance present in the extract is the inhibitory transmitter, then the r ... | 1979 | 497534 |
| [transformation of bile acids by bacteroides fragilis strains isolated from the human intestine (author's transl)]. | | 1979 | 490901 |
| cardio- and hemodynamic characterization of x-ray contrast media after intravascular administration. | | 1979 | 493305 |
| the role of anaerobic bacteria in postpartum endomyometritis. | to evaluate the role of anaerobic bacteria in postpartum endomyometritis, intravenous metronidazole was used as the sole initial therapy in 25 women with clinical signs of infection. this agent has not been shown to have activity against aerobic pathogens in soft tissue pelvic infections. a clinical cure was obtained in 21 of 25 (84%) with oral metronidazole utilized after the patient had been afebrile for at least 24 hours. the mean fever index of the 21 successfully treated women was 35.9 degr ... | 1979 | 495683 |
| the origin of two components in contraction of guinea pig papillary muscle in the presence of noradrenaline. | in experiments on isolated guinea pig papillary muscles the effects of verapamil (5 mg/l) and caffeine (1 g/l) on the two-component contraction were investigated. the muscles were continuously superfused with normal tyrode's solution containing 2 mg of noradrenaline/l at 20--22 degrees c. the first derivative of contractile response and transmembrane action potential were simultaneously recorded. verapamil suppressed the amplitude of the second component and had no influence on the first compone ... | 1979 | 497900 |
| [serological reactivity of healthy and ill people in relation to antigens from bacteroides-serotypes (author's transl)]. | we investigated sera of healthy and ill people with different diagnoses to their reactivity against antigens isolated from six serotypes a--e2 (subspecies) of bacteroides fragilis in indirect hemagglutination tests. these investigations were conducted partly in poland and partly in the netherlands. - in many cases antibodies towards several serotypes of bacteroides fragilis were present in the healthy. in the netherlands we found antibodies towards serotypes c and e2; in poland serotypes d and e ... | 1979 | 506560 |
| in vitro activity of ly127935. | the activity of ly127935, a beta-lactam antibiotic of novel structure, was studied in vitro against facultative gram-negative bacilli, staphylococcus aureus, and bacteroides fragilis. the strains were recent clinical isolates, many of which were relatively resistant to other antibiotics. ly127935 exhibited striking activity against escherichia coli, klebsiella pneumoniae, enterobacter sp., proteus sp., serratia marcescens, and b. fragilis with median minimum inhibitory concentrations of less tha ... | 1979 | 507785 |
| ly127935, a novel oxa-beta-lactam: an in vitro comparison with other beta-lactam antibiotics. | the in vitro activities of ly127935 (ly) were compared with those of other beta-lactam antibiotics. ly was highly active (minimal inhibitory concentration [mic] range 0.06 to 0.25 micrograms/ml) against the common enterobacteriaceae (including providencia stuartiia, enterobacter, and serrati marcescens), 8 to 16 times more active than cefoxitin, cefuroxime, or cefazolin, and from one-half to one-eighth as active as cefotaxime (hr756). the activity of ly against pseudomonas aeruginosa (with mics ... | 1979 | 507788 |
| effect of alcohol on thermal balance of man in cold water. | the effects of alcohol on core cooling rates (rectal and tympanic), skin temperatures, and metabolic rate were determined for 10 subjects rendered hypothermic by immersion for 45 min in 10 degrees c water. experiments were duplicated with and without a 20-min period of exercise at the beginning of cold water immersion. measurements were continued during rewarming in a hot bath. with blood alcohol concentrations averaging 82 mg 100 ml-1, core cooling rates and changes in skin temperatures were in ... | 1979 | 497899 |
| characterization of different forms of the androgen receptor. | three forms of the androgen receptor have been characterized at high ionic strength in partially purified cytosol and nuclear fractions of rat ventral prostate, epididymis, testis, and seminal vesicle by ion exchange chromatography on phosphocellulose, gel filtration in sephadex g-200, and sedimentation in sucrose gradients. the three forms have the following properties, respectively: elution from phosphocellulose at 0.15--0.20, 0.3--0.5, and 0.20--0.32 m kcl; gel filtration radii of 53, 36, and ... | 1979 | 499078 |
| microorganisms seen by scanning and transmission electron microscopy in legionnaires' disease from human lung. | in addition to several anomalous structures, other general forms of definitely rod-shaped microorganisms have been found by scanning and transmission electron microscopy in the lung tissue taken at autopsy from a patient who succumbed to confirmed legionnaires' disease with extensive necrotizing lobar pneumonia. the microorganisms were greatly varied in size and shape. they were micrographed in the act of fission. these forms have been found to some extent throughout the tissue. no nickel was de ... | 1979 | 499405 |
| a fatal case of wesselsbron disease in a dog. | | 1979 | 516330 |
| collaborative evaluation of a proposed reference dilution method of susceptibility testing of anaerobic bacteria. | an agar dilution method for susceptibility testing of anaerobic bacteria was evaluated to determine whether results obtained would be consistent enough to recommend it as a reference method. the study was conducted in 10 laboratories where the minimum inhibitory concentrations of six antibiotics (carbenicillin, cefoxitin, chloramphenicol, clindamycin, penicillin g, and tetracycline) were determined against 10 bacterial strains on wilkins-chalgren agar prepared by three manufacturers. minimum inh ... | 1979 | 518079 |
| in vitro activity of ly127935. | ly127935 is a unique new beta-lactam antibiotic. its activity against 536 clinical isolates was studied by using microdilution methods of susceptibility testing and compared with the activities of cefamandole, cefoxitin, and cephalothin. the lowest concentrations required to inhibit at least 90% of strains tested (mic(90)s) of ly127935 for staphylococcus aureus, streptococcus pyogenes, streptococcus agalactiae, and streptococcus pneumoniae ranged from 2 to 8 mug/ml. the mic(90)s for other staphy ... | 1979 | 518080 |
| bacteroides infection in fibroids during the puerperium. | | 1979 | 519275 |
| the lipid composition of rat brain aggregating cell cultures during development. | the lipid and fatty acid composition of rat brain was studied during its development both in vivo and in an aggregating cell culture system. although the amount of lipid present in the cultures was very low, the increase in glycolipid content corresponded closely to the period of intense myelin formation. very long chain fatty acids (hydroxylated and unsubstituted) were present in 41-day cultures. in comparison to the in vivo situation, myelination was delayed in vitro and, after 40 days in cult ... | 1979 | 514541 |
| inactivation of neurohypophysial hormone release in the rat by substitution of saline solution for drinking water [proceedings]. | | 1979 | 522005 |
| studies on selective induction of lysosomal enzyme activities in mouse peritoneal macrophages. | | 1979 | 522087 |
| interactions of folch-lees proteolipid apoprotein with planar lipid bilayers. | water-soluble folch-lees proteolipid apoprotein from bovine cns white matter induces a voltage-dependent conductance in black lipid membranes. na+ is required for the induced conductance change but the established conductance has very low ionic selectivity. the induced conductance fluctuates with a minimum amplitude of 10(-11)--10(-10) mho. the magnitude of the conductivity change is dependent on protein concentration and on the composition of lipid bilayers. at a fixed voltage the induced condu ... | 1979 | 522128 |
| [problems of the disease due to mycobacteria other than tubercle bacilli: surgical treatment and indication (author's transl)]. | | 1979 | 522352 |
| chemotaxis or migration inhibition of rabbit peritoneal polymorphonuclear leukocytes caused by chemoattractants at various concentrations. | purified lipopolysaccharide (lps) from veillonella incubated in normal rabbit serum was tested for chemotactic activity on rabbit polymorphonuclear leukocytes (pmns) in modified boyden chambers. in doses above those giving optimal response (over-optimal dose), a decrease of the pmn migration activity was found. this decrease also correlated well with an increase in the migration inhibition of the pmns as demonstrated with the capillary tube assay. the pmn chemotactic factor isolated from lps-ind ... | 1979 | 525354 |
| inactivation of cephalosporins by bacteroides. | we investigated the relationship between beta-lactamases of bacteroides fragilis organisms and their resistance to cephalosporins. timed killing curves were used to study the in vitro activity of three cephalosporins, cephalothin, cefazolin, and cefamandole, and a semisynthetic cephamycin, cefoxitin. measurements of residual antibiotic concentrations in culture supernatants were made, and they were compared with the beta-lactamase activity of the microorganism. a cephalosporin-susceptible strain ... | 1979 | 525995 |
| variability in the susceptibility pattern of bacteroides fragilis in four detroit area hospitals. | recent clinical isolates of bacteroides fragilis selected at random from four detroit area hospitals were collected over a 3-month period, and the minimum inhibitory concentrations were determined within several days. the levels of antimicrobial agents used in this survey breached the concentration attainable in the patient's serum. the antimicrobial susceptibility patterns of these isolates to five antimicrobial agents suggest that there is a 20% variation in the resistance to clindamycin and a ... | 1979 | 526009 |
| bacteroides fragilis in acute salpingitis. | the bacteriology of acute salpingitis was studied in 87 patients. gonococci were recovered from 18 patients. lower yields of bacteria were isolated in the peritoneal fluid than from the vaginal cultures, and a poor correlation was observed between the peritoneal fluid and vaginal cultures. anaerobic bacteria dominated in both sites. staphylococci, streptococci, enterobacteria, peptostreptococci, peptococci, lactobacilli and bacteroides normally present in the vagina were the predominant isolates ... | 1979 | 511341 |
| diffusion of anions and cations in the extracellular micro-environment of the brain [proceedings]. | | 1979 | 529139 |
| synthesis of alpha-ketoglutarate by reductive carboxylation of succinate in veillonella, selenomonas, and bacteriodes species. | evidence for reductive carboxylation of succinate to synthesize alpha-ketoglutarate was sought in anaerobic heterotrophs from the rumen and from other anaerobic habitats. cultures were grown in media containing unlabeled energy substrates plus [14c]succinate, and synthesis of cellular glutamate with a much higher specific activity than that of cellular asparate was taken as evidence for alpha-ketoglutarate synthase activity. our results indicate alpha-ketoglutarate synthase functions in selenomo ... | 1979 | 533772 |
| [microionophoretic study of the mechanism of action of gamma-hydroxybutyrate]. | the effect of gamma-hydroxybutyric acid (ghba) on the extracellularly registered spontaneous electrical activity of nervous cells of the rabbit brain sensomotor cortex was studied using the microionophoretic technique. ghba decreased the frequency of action potential in the majority of the neurons studied. a specific gamma-aminobutyric acid (gaba) blocking agent bicuculline prevented gbha inhibitory effect. ghba is suggested to interact with central gaba-receptors. the frequency of discharges in ... | 1979 | 540145 |
| [clindamycin levels in the cervical mucus after intramuscular administration of the drug (author's transl)]. | female genital tract is a major area of anaerobic infections. clindamycin has been used as a highly active antibiotic against both gram positive and negative anaerobic pathogens including bacteroides fragilis. concentration of clindamycin in cervical mucus has been tested in 30 women after administration of one single dose (600 mg) of the antibiotic intramuscularly. antibiotic levels were tested by agar diffusion method employing a strain of alpha-hemolytic streptococcus. levels of clindamycin i ... | 1979 | 541482 |
| obligate anaerobes in clinical veterinary practice. | clinical specimens obtained from domestic animals were examined to determine the relative prevalence of obligate anaerobic bacteria and the species represented. of 3,167 samples cultured anaerobically as well as aerobically, 2,234 were bacteriologically positive. of these positive samples, 583 (26%) contained species of obligate anaerobic bacteria in a total of 641 isolates. most positive samples contained anaerobes admixed with aerobic species, although 6% of such samples yielded pure cultures ... | 1979 | 511987 |
| induction of tk polyagglutination by bacteroides fragilis culture supernatants. associated modifications of a b h and i i antigens. | tk transformed red blood cells were obtained in vitro by treatment with supernatants from cultures of three different bacteroides fragilis strains. the reactions of these cells with ab sera show that tk is different from other known types of polyagglutination. beside the already known modifications of a b h antigens, we found that tk activated cells have an important modification of i and i antigens: both are reduced, and can even be completely destroyed. | 1979 | 547352 |
| surface antigens as virulence factors in infection with bacteroides fragilis. | organisms of the genus bacteroides represent the major group of obligate anaerobes involved in human infections. bacteroides usually cause either bacteremia or localized abscesses. of the numerous species of bacteroides, bacteroides fragilis is the single most frequent clinical isolate. b. fragilis and bacteroides melaninogenicus have chemically incomplete lipopolysaccharides as compared with the lipopolysaccharides (endotoxins) of aerobic bacteria, and the lipopolysaccharides of bacteroides lac ... | 1979 | 549184 |
| the chemotactic effect of bacteroides fragilis lipopolysaccharide. | the atypical bacteroides fragilis lipopolysaccharide is chemotactic for polymorphonuclear leukocytes. the chemotactic activity is mediated by complement activated through the alternative pathway. this mediator has been isolated. it is a polypeptide with a molecular weight of 16,000 and is most likely the complement component c5a. | 1979 | 549186 |
| participation of immunoglobulin and the alternative complement pathway in opsonization of bacteroides fragilis and bacteroides thetaiotaomicron. | studies were conducted to determine the requirements for immunoglobulin and complement in opsonization of bacteroides fragilis and bacteroides thetaiotaomicron. the ability of human sera depleted of immunoglobulin or of components of complement to promote the phagocytosis and intracellular killing of the two strains of bacteroides by human leukocytes was measured in vitro under anaerobic conditions. neither hypogammaglobulinemic sera nor pooled normal human serum that was heated at 56 c for 30 ... | 1979 | 549187 |
| [schistosomiosis infection produced by human and wild strains from the rio paraiba do sul valley sp (brazil), in isogeneic mice]. | | 1979 | 549223 |
| protective efficacy of immunization with capsular antigen against experimental infection with bacteroides fragilis. | the protective efficacy afforded by immunization with the capsular antigen of bacteroides fragilis against abscess formation and bacteremia due to this organism was studied in an experimental rat model of intraabdominal sepsis. of unimmunized animals, animals immunized with methylated bovine serum albumin and complete freund's adjuvant, and animals immunized with lipopolysaccharide of bacteroides thetaiotaomicron, greater than 90% developed abscesses when challenged intraperitoneally with strain ... | 1979 | 528789 |
| organochlorinated pesticides in the argentine antarctic sector and atlantic coastline waters. | the presence of organochlorinated pesticides in water samples drawn in the argentine antarctic sector and atlantic coastline has been proved. in general, these samples showed quantities that varied between a few hundredths of a ppmm to slightly more than 1 ppmm, although in some cases and for certain pesticides, depending on the locations, the levels found were definitely higher. with the exception of dieldrin, which appeared in only one sample/in what would seem to be its course few hundredths ... | 1979 | 546680 |
| susceptibility of aerobic and anaerobic gram-negative rods to cefoxitin and related compounds. | | 1979 | 521267 |
| neck and macular labyrinthine influences on the purkinje cells of the cerebellar vermis. | | 1979 | 551449 |
| [applications of gas chromatography in the diagnosis of anaerobic infections]. | the isolation and identification of anaerobic bacteria by biochemical tests take long time, so it is very useful the gas-chromatography to detect the volatile fatty acids produced from their metabolism. this technique can give rapidly a presumptive diagnosis of anaerobic infection so that it is possible to start immediately a correct antibiotic therapy. in this study we have examined many samples of pus and exudate, and the results have been compared with those obtained from the culture. we have ... | 1979 | 553479 |