| [clinical and experimental study on hepatorenal syndrome in terms of obstructive jaundice (author's transl)]. | in our department, hepatorenal syndrome was highly associated with obstructive jaundice and was seen in 9.2 percent of patients with obstructive jaundice. this syndrome developed when in underlying hepatic disease, acute renal failure supervened. histological findings of renal failure caused by obstructive jaundice were summarized as tubular necrosis and the presence of protein-like substance in the glomerulus, which were mostly reversible and similar to those seen in shock. to investigate the p ... | 1978 | 352884 |
| nonspecific immunostimulant activities of synthetic trehalose-6,6'-diesters (lower homologs of cord factor). | mycobacterial cord factors (6,6'-diesters of trehalose with mycolic acids ranging from c80 to c90) have been shown to protect mice effectively against infection with klebsiella pneumoniae or with listeria monocytogenes. our present findings indicate that the low-molecular-weight cord factor of corynebacterium diphtheriae (with corynomycolic acids ranging from c28 pto c36) is equally active. moreover, its synthetic analog (with synthetic c32 mycolic acid) has the same activity. two lower syntheti ... | 1978 | 352926 |
| bacterial colonization of neonates admitted to an intensive care environment. | in order to elucidate some of the factors responsible for the high rate of nosocomial infection associated with neonatal intensive care, we studied bacterial colonization in 63 infants admitted to a neonatal intensive care unit. in a six-month period, cultures of nose, throat, umbilicus, and stool were obtained on admission and every three days from all infants staying in the nicu greater than or equal to 3 days. study infants did not develop "normal" aerobic flora. forty-eight percent of infant ... | 1978 | 353239 |
| [selected chapters from clinical bacteriology. vi. enteric bacteria]. | | 1978 | 353784 |
| [cadaverine is an intermediate in the biosynthesis of arthrobactin and ferrioxamine e (author's transl)]. | cadaverin was more readily incorporated than lysine into arthrobactin from arthrobacter pascens and into ferrioxamin e from streptomyces glaucescens. from a racemic mixture only the l-isomer of lysine is incorporated. the l-lysine decarboxylase activity was measured in vivo and in vitro. the enzyme from arthrobacter pascens is not inducable by lysine and completely repressed by 5.10(-6) m fe3+. in klebsiella pneumoniae, the producer of aerobactin, only a very low activity of l-lysine decarboxyla ... | 1978 | 354550 |
| [microbiological examinations in the intensive surgical care unit of the general calixto garcia teaching hospital]. | microbiological examinations carried out in the intensive surgical-care unit of the "calixto garcía" teaching hospital between october, 1974 and february, 1976 are exposed. nineteen examinations were carried out in the unit and results were as follows: 53,1% of the personnel had pathogenic germs (43,8%, coagulase-positive staphylococci; 6,3%, beta-hemolytic streptococci; and 6,3%, klebsiella). acceptable results were obtained in the unit air but it was not the case in laboratory and nursery sect ... | 1977 | 354643 |
| immunochemistry of nitrogenase as a probe for the enzyme mechanism. evidence for multiple enzyme forms and an mgatp2- binding site on the mofe protein. | | 1978 | 354962 |
| scleroma--bacteriological and preliminary experimental studies. | | 1977 | 355138 |
| enterotoxin-producing bacteria stools from swedish united nations soldiers in cyprus. | a study was designed to establish the role of heat-labile enterotoxin producing escherichia coli and other intestinal pathogens in diarrhoeal disease in swedish soldiers of the united nations' force in cyprus. before leaving sweden for cyprus, no enteropathogens were isolated from the soldiers. the study was performed from october 1975 through january 1976 and in august 1976. enterotoxigenic strains of e. coli, citrobacter freundii, enterobacter cloacae and klebsiella pneumoniae were the intesti ... | 1978 | 355145 |
| comparative pathogenicity of environmental and clinical klebsiella. | | 1978 | 355207 |
| differentiation of serratia marcescens and serratia liquefaciens by tests for lipase and phospholipase production. | the production of lipase and phospolipase by certain members of the enterobacteriaceae was examined by thin-layer chromatography of resting-cell suspensions incubated with triolein or lecithin. most strains of serratia marcescens produced both enzymes while most strains of serratia liquefaciens exhibited strong lipase but only a minor phospholipase activity. enterobacter spp. (25 strains), klebsiella pneumoniae (20 strains), escherichia coli (15 strains), citrobacter freundii (7 strains) and pro ... | 1978 | 355631 |
| enhancement of the neonate's nonspecific immunity to klebsiella infection by muramyl dipeptide, a synthetic immunoadjuvant. | n-acetylmuramyl-l-alanyl-d-isoglutamine (muramyl dipeptide) and certain derivatives that are structural analogs of part of the bacterial peptidoglycan monomer have been shown to be adjuvant active and to enhance the nonspecific immunity of adult mice infected by klebsiella pneumoniae. in the present study muramyl dipeptide and two other synthetic analogs were found to be active in newborn mice. this activity could be demonstrated after administration by subcutaneous or even by oral route. in con ... | 1978 | 356054 |
| experimental gram-negative bacterial sepsis: reevaluation of the ability of rough mutant antisera to protect mice. | | 1978 | 356058 |
| kidney stones and renal transplantation. | only 10 cases of renal calculi in transplanted kidneys are reported in the literature. etiology is not uniform in all the cases. some of these cases were managed conservatively. we herein report a case in which the etiology of the stone may be urinary tract infection. this patient was managed conservatively. | 1978 | 356391 |
| sodium clavulanate potentiation of cephalosporin activity against clinical isolates of cephalothin-resistant klebsiella pneumoniae. | plasmid-carrying klebsiella pneunomiae clinical isolates with agar dilution minimum inhibitory concentrations (mic) of 32 mug/ml or greater were tested for in vitro potentiation of cephalothin activity by clavulanic acid (brl-14151), an inhibitor of beta-lactamases. the addition of 10 mug of clavulanate per ml caused greater than a 500-fold reduction in geometric mean cephalothin agar dilution mic, with lesser but significant reductions resulting from clavulanate concentrations of 5 or 1 mug/ml. ... | 1978 | 356723 |
| klebsiella pneumoniae. | | 1978 | 356762 |
| amikacin in gram-negative paediatric infections. | amikacin was used in the treatment of various gram-negative infections in sixty-six children ranging in age from two days to thirteen years. over 72% of the infections treated were classified as severe and the remainder were moderate. among infections in which the site of origin was the urinary or gastro-intestinal tract, amikacin achieved thirty-eight (95%) complete or partial cures in forty patients. in respiratory tract infections, amikacin completely or partially cured six (75%) out of eight ... | 1978 | 357227 |
| clinical experience with cefadroxil in upper and lower respiratory tract infections. | cefadroxil is a new semisynthetic oral cephalosporin with a broad spectrum of activity against both gram-positive and gram-negative organisms. absorption of cefadroxil is unaffected by food, its serum levels are prolonged and it is excreted in the urine at a relatively slow rate compared to cephalexin. in the treatment of 108 patient with upper or lower respiratory tract infections, cefadroxil effected 93% complete cures. fifty-five of the patients had upper respiratory tract infections and fift ... | 1978 | 357229 |
| [methods of determining fecal citrate-positive enterobacteriaceae]. | | 1978 | 357255 |
| transconjugant analysis: limitations on the use of sequence-specific endonucleases for plasmid identification. | we used the sequence-specific endonucleases ecori, smai, bamhi, hsui, and haeiii as identification tools in following the conjugal transfer of the well-studied r plasmids sa, r388, rp4, and r6k. transfers were both intergeneric and intrageneric. plasmid fingerprints were generated from both single- and combination-enzyme digests. the sa transconjugants yielded plasmids showing consistent fingerprints for each of the respective endonucleases used, whereas the three other r-plasmid transconjugants ... | 1978 | 357414 |
| false-positive cryptococcal antigen test and cervical prevertebral abscess. | a false-positive latex agglutination test for cryptococcal antigen occurred in a patient with a cervical prevertebral abscess and vertebral osteomyelitis caused by klebsiella pneumoniae. using a commercial latex agglutination test kit, a cryptococcal antigen titer of 1:32 was found in the csf, but no cryptococcal antigen was found when the csf was retested at a reference laboratory. the false-positive test resulted in unnecessary therapy with amphotericin b and delay in appropriate diagnostic st ... | 1978 | 357768 |
| preferential uptake of thymidine by thymineless enterobacteria: its significance in dna labelling. | minimum satisfactory concentrations of thymine and thymidine were determined for the growth of a high thymine-requirng (thy) mutant to escherichia coli strain j5-3. cultures were then grown in the presence of these concentrations of non-radioactive ('cold') pyrimidine together with 5 microci/ml [methyl-3h)thymine, or [methyl-3h)thymidine (specific activities 5 ci/m mole), and the uptake of radioactivity into ice cold trichloroacetic acid insoluble material determined. by far the most efficient l ... | 1977 | 357930 |
| in vivo formation of transmissible resistance factor by recombination between nontransmissible resistance factor and col b factor. | germ-free swine were artificially contaminated with tetracycline (tc) sensitive strains of escherichia coli and klebsiella pneumoniae. one of these strains, e. coli 3306, was infected with a plasmid carrying kanamycin (km) resistance, i.e., t-kan factor. another strain, e. coli p-5, carried a conjugally transferable col b factor. among the nine strains used, only e. coli p-38 became tc-resistant after tc administration. three types of tc-resistance e. coli p-38 strains were found; (a) one strain ... | 1978 | 357932 |
| [rifampicin in klebsiella pneumoniae septicemia]. | | 1978 | 357959 |
| otitis media in the neonatal intensive care unit. | thirty-eight of 125 premature infants who were hospitalized in a neonatal intensive care unit (nicu) had abnormal tympanic membrane mobility compatible with otitis media. twenty-five of these 38 had received antibiotics within one week of otoscopic examination and were considered to have either serous otitis or partially treated bacterial otitis media; tympanocentesis was not performed in them. tympanocentesis was performed in the remaining 13 infants who had not received antibiotics. bacterial ... | 1978 | 358121 |
| urinary tract infections in girls: age at onset and urinary tract abnormalities. | | 1978 | 358124 |
| electronmicroscopic finding of surface structure and capsular swelling reaction of a strain of klebsiella pneumoniae. | to investigate a capsular swelling reaction of the strain k-9 of klebsiella pneumoniae, possessor of large capsule, ultra-thin sections of the organisms were stained with uranyl acetate and lead citrate and were treated with rabbit antiserum. the ultra-thin sections of above stained organisms showed spike-like structure in outmost layer of the cell wall. when they were treated with rabbit antiserum, the outmost layers of the organisms was surrounded by a zone of oval to round polymorphous vesicu ... | 1978 | 358675 |
| analysis of amines and other bacterial products by head-space gas chromatography. | a gas chromatographic (gc) head-space technique is presented, which is suitable for the analysis of volatile products in bacterial broth cultures. this is exemplified by studies on clostridium septicum, klebsiella pneumoniae and proteus mirabilis. the media were acidified or made alkaline and after heating, samples of the gas phase above the media were directly injected into the gas chromatograph. a gas chromatograph equipped with dual columns and flame ionization detectors was used, employing p ... | 1978 | 358746 |
| [klebsiella pneumoniae infection in immunosuppressed mice treated with gentamicin (author's transl)]. | experiments have been established in order to study the antagonistic effect of cyclophosphamid treatment on the antibiotic activity of gentamicin in vivo. an immunodepressive state in mice (50 % reduction of neutrophil polymorphonuclear) was obtained with a 5 day treatment of cyclophosphamid, at the dose of 15 mg/kg. the mice were inoculated intraperitoneally with 10 ld50 of klebsiella pneumoniae. antibiotherapy was applied in 2 ways differing with the dose of gentamicin given twice a day by sub ... | 1978 | 358887 |
| isolation of klebsielleae from within living wood. | previous studies from this laboratory have documented the presence of coliform bacteria emanating from wooden reservoirs containing finished drinking water. coliforms were identified as klebsiella pneumoniae and enterobacter spp. in the present report, evidence is presented which suggests that the origin of these coliforms is from the wood used to construct the reservoirs. in liquid expressed from freshly cut redwood, total bacterial counts in the range of 10(5) to 10(6)/ml were commonly observe ... | 1978 | 358920 |
| lytic activity of a new cephalosporin, cefuroxime, against gram-negative bacteria. | cefuroxime, a new cephalosporin antibiotic, was inhibitory at low concentrations to several types of gram-negative bacteria. it was considerably more stable than cephaloridine or cephalothin to the beta-lactamases produced by escherichia coli (rp1), klebsiella aerogenes k1 and enterobacter cloacae p99. concentrations of cefuroxime much greater than the minimum inhibitory concentration (mic) were usually necessary to induce lysis of beta-lactamase and non-beta-lactamase producers. in contrast, ce ... | 1978 | 359269 |
| [nosocomial infection of hospitalised patients with chemotherapy-resistant strains of klebsiella pneumoniae (author's transl)]. | in a 500-bed general hospital the incidence of highly resistant strains of klebsiella pneumonia was examined. about 20% of examined patients in the surgical and medical departments were carriers. spread of the organism was via the hands of personnel and patients as well as various objects. the use of broad-spectrum antibiotics, especially ampicillin and cefalotin is thought to be the chief cause of the high incidence of klebsiella emergence. about 90% of carriers had previously received antibiot ... | 1978 | 359292 |
| a comparison of the minimum inhibitory concentrations of sisomicin and of fourteen other antibiotics. | the activities of sisomicin and of fourteen other antibiotics have been compared for their inhibitory activity on all the different strains of bacteria isolated from a 3,000 bed hospital. the antibiotic sensitivity tests were performed in liquid medium and expressed as minimum inhibitory concentrations. the tests were performed over a period of four months. the results are discussed. | 1978 | 359385 |
| [new aspects of the value of endotoxins in various gastrointestinal diseases]. | recent investigations of several authors on portal venous and systemic endotoxemia in healthy adults have shown that endotoxins absorbed from the intestinal mucosa are found in portal venous blood, cleared by the res of the liver and usually cannot be determined in peripheral blood. in patients with liver disease, however, there was often a reduced endotoxin clearance with spillover of endotoxin resulting in systemic endotoxemia. among the complications of systemic endotoxemia, hepatocytotoxicit ... | 1978 | 359442 |
| competition of the actions of antigen and polyclonal b-cell activator in the induction and amplification of b-memory cell function. | using the capsular polysaccharide of klebsiella pneumoniae (cps-k) as a polyclonal b-cell activator (pba) and sheep red blood cells (srbc) as a t-dependent antigen, the correlation of the actions of pba and t-dependent antigen on b cells in induction and amplification of immunological memory was studied. b-memory cell function, as judged by anti-srbc responsiveness in vitro of spleen cells of cps-k, was amplified by the secondary injection of srbc into srbc-primed mice, whereas it was decreased ... | 1978 | 359463 |
| analysis of increasing antibiotic resistance of klebsiella pneumoniae relative to changes in chemotherapy. | three antibiotic-resistant strains of klebsiella pneumoniae responsible for outbreaks of systemic infection in a hospital nursery were analyzed. each organism emerged after prolonged use of a drug to which it was resistant. the first strain (ro16) produced neomycin phosphotransferase and contained three plasmids with molecular weights of 24, 25, and 30 x 10(6) daltons, respectively. resistance to ampicillin, carbenicillin, neomycin, and kanamycin was transferred by conjugation at a frequency of ... | 1978 | 359724 |
| differences in etiology of pneumonias in nursing home and community patients. | comparison of 35 elderly patients hospitalized with pneumonia acquired in nursing homes and 35 elderly patients hospitalized with community-acquired pneumonia showed that 16 (47.1%) of the nursing home patients had received previous antibiotic therapy compared with two (5.9%) of the community patients. klebsiella pneumoniae was isolated in 14 (40%) of the nursing home patients, but in only three (8.6%) of the community patients. staphylococcus aureus was also more frequent in nursing home patien ... | 1978 | 359845 |
| performance of enterobacteriaceae identification systems. an analysis of college of american pathologists survey data. | commercial systems designed and marketed for evaluation of enterobacteriaceae are used in many clinical microbiology laboratories. evaluations of these systems have been reported from several large laboratories. identifications with one or more of these systems were compared with those obtained by conventional methods with many strains of organisms. the microbiology resource committee of the college of american pathologists designed two surveys to evaluate the performances of commercial systems ... | 1978 | 360823 |
| inhibition of protein synthesis by three erythromycin-derivatives. | | 1978 | 361037 |
| immunological relationship of different preparations of coliform enterotoxins. | antisera raised in rabbits to ultrafiltrate toxin preparations containing either the heat-labile (lt) toxin form obtained from whole cell lysates or broth filtrates or the heat-stable (st) toxin form prepared from broth filtrates from nontoxigenic and toxigenic strains of escherichia coli and klebsiella were examined for their ability to neutralize the secretory effect on water transport of these toxins in the rat jejunum as determined by the in vivo marker perfusion technique. antisera to the h ... | 1978 | 361578 |
| effect of immunization of bacterial adherence to urothelium. | in order for a urinary tract infection to begin, the pathogenic bacteria must first adhere to the urothelial surface. an in vivo method for quantitation of bacterial adherence to urothelium has been developed. immunization by instillation of bacterial antigens into the rat bladder decreased bacterial adherence. bladder immunization was more effective than subcutaneous immunization. preinfection by escherichia coli decreased subsequent adherence of klebsiella pneumoniae. increasing antiadherence ... | 1978 | 361628 |
| 6-cyanopurine, a color indicator useful for isolating mutations in the nif (nitrogen fixation) genes of klebsiella pneumoniae. | 6-cyanopurine (6-cp) can be used as a color indicator for certain classes of nif (n2 fixation) mutations in klebsiella pneumoniae. under n2-fixing conditions, nif+ colonies and most nif- colonies are purple on media containing 6-cp. twenty-two nif- mutants with altered color on medium containing 6-cp were isolated. all white mutants contained mutations in the regulatory genes, nifaa-nifl. mutants which were more darkly colored than the wild type had mutations distributed among six nif genes. med ... | 1978 | 361692 |
| fine-structure mapping and complementation analysis of nif (nitrogen fixation) genes in klebsiella pneumoniae. | four hundred and eighty-nine independent nif- strains containing 260 point, 130 millimicron-induced, and 99 deletion mutations in nif in the klebsiella pneumoniae chromosome were isolated. three hundred and ninety insertion and point mutations were mapped with millimicron-induced deletions carried on 44 plasmids derived from ptm4010, a recombinant r factor containing the his-nif region of k. pneumoniae. the 99 chromosomal deletions in the nif region were mapped with 69 derivatives of ptm4010 car ... | 1978 | 361693 |
| regulation and characterization of protein products coded by the nif (nitrogen fixation) genes of klebsiella pneumoniae. | two hundred and thirty-five nif- strains of klebsiella pneumoniae were characterized by two-dimensional polyacrylamide gel electrophoresis. forty-two of these strains were tested further by in vitro acetylene reduction assays. by these techniques, nine nif-coded polypeptides were identified, and eight of these were assigned to specific nif genes. nitrogenase component i required nifk and nifd, which coded for the beta and alpha subunits, and nifb, -e, and -n were required for the iron-molybdenum ... | 1978 | 361694 |
| genetic mapping of tyramine oxidase and arylsulfatase genes and their regulation in intergeneric hybrids of enteric bacteria. | the genes for arylsulfatase (atsa) and tyramine oxidase (tyna) have been mapped in klebsiella aerogenes by p1 transduction. they are linked to gdhd and trp in the order atsa-tyna-gdhd-trp-pyrf. complementation analysis using f' episomes from escherichia coli suggested an analogous location of these genes in e. coli, although arylsulfatase activity was not detected in e. coli. p1 phage and f' episomes were used to create intergeneric hybrid strains of enteric bacteria by transfer of the ats and t ... | 1978 | 361719 |
| distribution of enterobacteriaceae in recycled manure bedding on california dairies. | the distribution of coliform organisms on three california dairies which use a system of automatic flushing of alley ways and composted, recycled manure solids as free stall bedding for utilization of waste was studied. there was a wide distribution of escherichia coli, klebsiella, and enterobacter and to less extent citrobacter organisms. klebsiella were not commonly in bovine feces. composting manure solids effectively reduced coliform counts to few or to zero. however, if given proper conditi ... | 1978 | 361769 |
| alterations in stool flora resulting from oral kanamycin prophylaxis of necrotizing enterocolitis. | | 1978 | 361939 |
| hepatic abscess and osteomyelitis from klebsiella pneumoniae. | | 1978 | 361992 |
| polarity of mutations induced by insertion of transposons tn5, tn7 and tn10 into the nif gene cluster of klebsiella pneumoniae. | three new genes nifm, nifi and nifn have been mapped in the nif gene cluster of klebsiella pneumoniae and a fourth gene nifj has been confirmed as being a separate cistron. polar nif mutations were obtained by transposition of tn7 to plasmid prd1, and of tn5 and tn10 to plasmid pmf100, a derivative of prd1. complementation analysis of the nif::tn mutants led to the identification of at least six transcriptional units: nifb; nifa; nifj; nifh, nifd and nifk; nife and nifi; nifn, nifm and niff. bio ... | 1978 | 362160 |
| the significance of serum-sensitive bacilli in gram-negative bacteremia. | clinical findings from 76 patients (median age 67 years) with gram-negative bacteremia were analysed and related to the sensitivity of the blood isolates to the bactericidal activity of normal human serum. 28 strains (37%) were resistant, an equal number intermediately sensitive and 20 markedly sensitive (26%). no correlation was found between serum sensitivity and origin of the bacteremia, presence of fever or blood granulocyte count. the frequency of shock in immunocompromised patients with se ... | 1978 | 362514 |
| bacteriological and clinical studies of sulbenicillin. | a new semi-synthetic penicillin, sulbenicillin, was evaluated with regard to clinical effect on infections caused by pseudomonas aeruginosa and other bacteria, serum concentrations obtained after intravenous administration and antibacterial spectrum, in comparison with the closely related antibiotic carbenicillin. the antibacterial spectra of sulbenicillin and carbenicillin were similar but the mic values were lower for sulbenicillin against most of the bacterial strains tested. the serum concen ... | 1978 | 362518 |
| antiserum treatment of gram-negative bacteremia. | in order to lower the mortality rate from gram-negative bacteremia, 136 patients were treated with human antiserum against core glycolipid, or with control nonimmune human serum, in a double-blind clinical trial. the antiserum was prepared by immunizing healthy young men with a vaccine composed of heat killed cells of the j5 mutant of e. coli 0111 b4. since the core glycolipid in this mutant is not encumbered with "o" side chains, it can stimulate antibody against the core glycolipid possessed i ... | 1978 | 362528 |
| bladder surface mucin. its antibacterial effect against various bacterial species. | we previously reported the results of quantitative and histochemical studies implicating the surface mucin of the bladder mucosa as an important antibacterial defense mechanism, which functions by preventing bacteria from adhering to the bladder wall. we call the mucin "anti-adherence factor" and we feel this is a previously undocumented role for mucin as a type of host antibacterial defense. these experiments were conduced with escherichia coli. in an effort to determine whether the anti-adhere ... | 1978 | 362941 |
| bacteriuria in urinary schistosomiasis in egypt a prevalence survey. | an epidemiologic survey to assess the prevalence of bacteriuria in urinary schistosomiasis was carried out in a region endemic for urinary schistosomiasis in egypt. twenty of 390 (5.1%) school boys aged 5--16 years were bacteriuric. this prevalence rate is more than 10 times greater than that found in comparable surveys in areas non-endemic for urinary schistosomiasis. in this endemic population bacteriuria was found in 6.5% of active egg excreters and 2.3% of non-egg excreters. | 1978 | 362956 |
| pharyngeal flora in ambulatory alcoholic patients: prevalence of gram-negative bacilli. | the pharyngeal flora of a group of ambulatory alcoholic patients was studied and compared with the pharyngeal flora of a control group. sixty-eight patients were studied, 34 alcoholics and 28 controls. of the alcoholic patients, 59% had gram-negative bacilli in their pharyngeal flora, while 14% of the control group had the same organisms. there were no differences in gram-positive cocci colonization between the groups. klebsiella pneumoniae was the most frequent isolate (40%) and the klebsiella- ... | 1978 | 363086 |
| nitrogenase of klebsiella pneumoniae: a pre-steady state burst of atp hydrolysis is coupled to electron transfer between the component proteins. | | 1978 | 363454 |
| intraventricular administration of amikacin for complicated gram-negative meningitis and ventriculitis. | four pediatric neurosurgical patients with gram-negative meningitis and ventriculitis were treated with parenteral and intraventricular amikacin, a new aminoglycoside. the organisms infecting these patients were resistant to multiple antimicrobial drugs but were sensitive to amikacin. treatment was continued for 14 days after cerebrospinal fluid cultures became negative. all four patients were cured and have demonstrated no nephrotoxicity, ototoxicity, or evidence of persistent infection on foll ... | 1979 | 363982 |
| variation in metabolism of biochemical test substrates by klebsiella species: an epidemiological tool. | the variation in metabolism of biochemical test substrates by klebsiella isolates has been demonstrated. it is suggested that this variation is likely to result in false-negative reactions in biochemical tests incubated for short periods. the observations made may explain the reported difficulties in obtaining reproducible results in biotyping klebsiella strains. preliminary work suggests that differences in substrate metabolism will provide a means of increasing the sensitivity of methods for t ... | 1978 | 364067 |
| effect of cardiopulmonary bypass on in vivo clearance of live klebsiella aerogens. | | 1977 | 364718 |
| pathophysiologic responses to klebsiella aerogenes bacteria: 24-hour observations. | | 1977 | 364736 |
| acquisition of multiple antibiotic resistance by salmonella dublin from the gramnegative hospital flora, in a kidney allograft recipient. | the case of a kidney allograft recipient, who suffered from several episodes of salmonella dublin sepsis following massive immunosuppressive therapy to overcome a transplant rejection crisis, is presented. the focus of sepsis was the chronic inflamed gallbladder. the salmonella dublin strain isolated from the blood during the last episode was found to exhibit multiple resistance to antimicrobiol drugs. because the resistance phenotype was characteristic for the gramnegative flora of the universi ... | 1978 | 364885 |
| synergistic activity of gentamicin with trimethoprim or sulfamethoxazole-trimethoprim against escherichia coli and klebsiella pneumoniae. | the effect of combinations of gentamicin with trimethoprim or sulfamethoxazole-trimethoprim against clinical isolates of escherichia coli (11 strains) and klebsiella pneumoniae (12 strains) was examined by using a microdilution checkerboard technique. all isolates were susceptible to each antimicrobial agent. synergism, defined as at least a 2-log(2)-dilution lowering of the minimal inhibitory concentration of either antibiotic in the combination compared with the minimal inhibitory concentratio ... | 1978 | 365085 |
| primary klebsiella identification with macconkey-inositol-carbenicillin agar. | macconkey-inositol-carbenicillin agar has successfully been used as a primary selective medium for klebsiella enumeration. with pure cultures, nearly 100% recovery of klebsiella was observed by membrane filtration. with environmental samples using membrane filtration, 95% of typical pink- to red-colored colonies were verified as klebsiella, as opposed to only 1% of yellow background colonies. recovery of klebsiella on macconkey-inositol-carbenicillin agar was as good or better than on mendo agar ... | 1978 | 365108 |
| technical aspects of separation using aqueous two-phase systems in enzyme isolation processes. | | 1978 | 365256 |
| procedure for the simultaneous large-scale isolation of pullulanase and 1,4-alpha-glucan phosphorylase from klebsiella pneumoniae involving liquid-liquid separations. | a procedure for the simultaneous large-scale isolation of pullulanase and 1,4-alpha-glucan phosphorylase from klebsiella pneumoniae is described. the pullulanase is solubilized from the cell wall by cholate treatment; cells and cell debris are removed by partition in a poly(ethylene glycol) (peg)-dextran two-phase system and from the upper (peg) phase of this system the pullulanase is isolated by ultrafiltration and precipitation with n-cetyl,n-,n-,n-trimethyl ammonium bromide to a purity of abo ... | 1978 | 365257 |
| gram negative bone and joint infection: sixty patients treated with amikacin. | sixty patients with bone and joint infections secondary to gram negative infection were evaluated in relation to treatment with amikacin. forty-seven of these patients had osteomyelitis, and 13 had joint infections, including 3 prosthetic replacements. the patients' average was 35 years and there was no predilection for any particular skeletal location. only 6 patients had no associated predisposing medical problems. of these problems fracture, diabetes and narcotic abuse were most common. thirt ... | 1978 | 365414 |
| effect of monocontamination of germfree rats by enterotoxigenic coliform bacteria. | | 1979 | 365667 |
| antibody-independent interaction of the first component of complement with gram-negative bacteria. | the interaction of the first component of complement with two serum-sensitive strains of escherichia coli and klebsiella pneumoniae was studied. it could be demonstrated that highly purified c1, free of immunoglobulin g and immunoglobulin m, binds to e. coli or k. pneumoniae. c1 binding was also found with specifically absorbed human serum, after incubation of bacteria with normal serum in the presence of ethylenediaminetetraacetate or agammaglobulinemic serum; the number of c1 molecules taken u ... | 1978 | 365750 |
| secondary bacterial infection in bilharzial urological patients with special reference to the effect of tartar emetic on the causative micro-organisms. | | 1977 | 366058 |
| the capsules of corynebacterium equi and streptococcus equi. | the capsules of corynebacterium equi and streptococcus equi were examined by electron microscopy after staining with ruthenium red. they were compared with the capsule of klebsiella pneumoniae which had previously been examined using the same procedure (springer & roth, 1973). the capsule of c. equi had a laminated appearance. when s. equi was grown on solid medium, its capsule appeared as radially arranged projections capped by a thick electron dense layer. when grown in liquid medium, s. equi ... | 1978 | 366078 |
| modulation of influenza in mice by transfer factor therapy. | | 1978 | 366134 |
| close association between shape alteration and loss of immunity to superinfection in a wild-type klebsiella pneumoniae stable lysogen which can be both immune and nonimmune to superinfection. | klebsiella pneumoniae mirm7 is a wild-type strain which grows as cocci at ph 7 and above and as rods at ph 6.5 and below. cultures of this strain and an auxotrophic derivative, mirm7b, have been found to undergo spontaneous lysis after purification from possible contaminating viruses. lysates always contained two phages, fr2 and ap3, most often at high titers. fr2 and ap3 plated with the same efficiency on both mirm7b and k59 (another k. pneumoniae strain sensitive to fr2 and ap3) and lysogenize ... | 1978 | 366180 |
| lysogenic conversion in klebsiella pneumoniae: system which requires active immunity regulation for expression of the conversion phenomenon. | we have previously described klebsiella pneumoniae mirm7b, which, although stably lysogenic for the inducible and nondefective phages fr2 and ap3, is not immune to superinfection by these same viruses. mira12b, a strain which is lysogenic for fr2 and ap3 and immune to superinfection, has been derived from mirm7b. the sensitivity of this strain and that of the nonimmune parent to several bacteriophages have been compared in this work. it has been found that, whereas mirm7b is sensitive to colipha ... | 1978 | 366181 |
| [synergistic effect of ampicillin and dicloxacillin on penicillin and cephalosporin-susceptible escherichia coli (author's transl)]. | an effect of a combination of ampicillin (abpc) and dicloxacillin (mdipc) on penicillins and cephalosporin-susceptible e. coli was determined. minimum inhibitory concentrations of the combined drug were as same as that of abpc, but bacterial growth was inhibited by the combined drug stronger than abpc, low activity of beta-lactamase was detected in sonicated e. coli 0.225 cells, and this activity was inhibited by relatively low concentration of mdipc. we considered that a weak synergism of the c ... | 1978 | 366193 |
| genetic and biochemical analysis of mutants induced by bacteriophage mu dna integration into klebsiella pneumoniae nitrogen fixation genes. | polar mutations were obtained by integration of bacteriophage mu c+ or mu cts dna into the klebsiella pneumoniae nif genes located on plasmid pce1, a derivative of prd1. in addition, nif deletions were isolated from nif::mu cts plasmids. complementation data allowed the characterization of twelve nif cistrons, nine corresponding to previously identified genes. polar effect of mu dna insertions suggested the existence of at least six transcription units: 1) nif k, nif d and nif h--2)nif a and nif ... | 1978 | 366377 |
| urinary tract infection in general practice. | in three studies, 616 patients (610 female and six male) presented with symptoms suggesting urinary tract infection (uti). of these, 321 had greater than 100 x 10(6) bacteria per litre in a midstream urine sample. none of the presenting symptoms could be considered to be a reliable indicator of bacteriuria. ninety percent of infected urines and 44 percent of uninfected urines had a raised white cell concentration. escherichia coli was the most common infecting organism (71.3 percent). next were ... | 1978 | 366474 |
| [analysis of penicillin and ampicillin resistance in bacteria i. resistance and beta-lactamase production in clinical isolates (author's transl)]. | the penicillin beta-lactamase (pbl) activity of the clinical isolates was measured at the same time by colorimetric microtitration, the iodometric method and chromatographic analysis. the minimal inhibitory concentration (mic) of ampicillin (ap) was determined for each isolate, the character of the coupled resistances, their frequency and distribution in the pbl producing and pbl-negative strains were also investigated. it was found that 1. the mic value was 100 microgram/ml in 87.5 per cent of ... | 1978 | 366997 |
| combined clinical and laboratory studies with carbenicillin and ticarcillin: use in infections involving anaerobic bacteria. | eleven patients with serious infections involving anaerobic bacteria were treated with carbenicillin (four patients) or ticarcillin (seven patients). all patients were cured clinically and bacteriologically of their infections. an in vitro study testing 157 recently isolated anaerobic organisms against 11 antibiotics showed chloramphenicol, carbenicillin, and ticarcillin at blood level concentrations to be inhibitory to more anaerobic strains than the other eight antibiotics tested. ticarcillin ... | 1978 | 367159 |
| klebsiella pneumoniae and acute anterior uveitis in ankylosing spondylitis. | | 1979 | 367506 |
| klebsiella pneumoniae infection with secondary hypopyon in tokay gecko lizards. | | 1978 | 367993 |
| the configuration and location of the ribosidic linkage in the prosthetic group of citrate lyase (klebsiella aerogenes). | the structure of the prosthetic group of citrate lyase (klebsiella aerogenes) was studied by nuclear magnetic resonance and mass spectrometry. the spectra at 360 mhz of the nucleoside moiety (2'-ribosyladenosine) show the absence of 2'-hydroxyl proton, thus confirming the 2' position as the site of attachment of the second ribose moiety to the dephospho-coa. this glycosidic linkage is found to be alpha(1" leads to 2') and is identical to that of poly(adp-ribose). studies of permethylation produc ... | 1979 | 368065 |
| chemotherapy of pneumonias. | | 1979 | 368330 |
| microbial adjuvant and autoimmunity. iii. histological studies of development of experimental autoimmune thyroiditis in mice immunized with syngeneic thyroid extract together with the capsular polysaccharide of klebsiella pneumoniae. | | 1978 | 368527 |
| [studies on the bacterial causes of neonatal mortality in foals. report on post-mortem findings (author's transl)]. | the causes of neonatal mortality in foals were studied over a period of two years. the total number of foals studied was 121. bacterial infection was found to be an important factor. infection caused by a. equuli (1.6%) which previously was the most important one, has been superseded by e. coli infection (56%). e. coli infections particularly occur during the first weeks of life and, depending on the course of the disease, give rise to various pathological changes. infections running an acute co ... | 1979 | 369036 |
| [progress in antibacterial chemotherapy]. | | 1978 | 369199 |
| search for cross-reacting antigens of oral acidogenic bacteria and members of the normal intestinal flora. | | 1978 | 369317 |
| empiric therapy of febrile granulocytopenic patients. | antibiotic therapy in granulocytopenic cancer patients, the risk factors predisposing these patients to infection, and the signs, symptoms and types of infections occurring in these patients are reviewed. the four most commonly isolated organism at most cancer treatment centers are escherichia coli, klebsiella spp., pseudomonas aeruginosa and staphylococcus aureus. early antimicrobial therapy with broad-spectrum antibiotics before culture results are known produces cure rates of approximately 70 ... | 1979 | 369364 |
| dental infection in a cirrhotic patient. source of recurrent sepsis. | a patient with alcoholic cirrhosis had multiple episodes of sepsis with klebsiella pneumonia. repeated searches for the source of infection finally revealed the organism in the root of a tooth. evidence indicated that this site was the primary source of infection. the importance of dental infections in alcoholics and the difficulty in diagnosing those infections are emphasized by this case. | 1979 | 369935 |
| transfer by bone marrow cells of increased natural resistance to klebsiella pneumoniae induced by lipopolysaccharide in genetically deficient c3h/he mice. | in a previous study we demonstrated that lipopolysaccharide failed to elicit nonspecific resistance in c3h/he lipopolysaccharide low-responder mice against klebsiella infection in contrast to its activity in a closely related histocompatible high-responder subline, c3heb/fe. complete restoration of lipopolysaccharide-induced protection against 10(5) klebsiella was obtained in the present study by transferring bone marrow from high-responder mice to the highly deficient c3h/he mice. the ability o ... | 1979 | 370012 |
| multi-laboratory evaluation of an automated microbial detection/identification system. | an automated and computerized system (automicrobic system [ams]) for the detection of frequently encountered bacteria in clinical urine specimens was tested in a collaborative study among six laboratories. the sensitivity, specificity, reliability, and reproducibility of the ams were determined, and the system was compared with conventional detection and identification systems. in this study, pure cultures and mixtures of pure cultures were used to simulate clinical urine specimens. with pure cu ... | 1978 | 370141 |
| enzyme-linked immunospecific antibody test for detecting antibody to klebsiella. | the enzyme-linked immunospecific antibody test was performed in standard test tubes and microtiter plates to meausre high-titer antibody against klebsiella capsular polysaccharide. initial studies were conducted with rabbit sera; other studies were conducted with the serum of a patient infected with type 9 klebsiella. both immunized rabbits and an infected patient disclosed high titers of anticapsular antibody. control sera from other immunized rabbits and other infected humans failed to show t ... | 1978 | 370145 |
| simultaneous nosocomial outbreaks caused by multiply resistant klebsiella pneumoniae types 2 and 30. | two simultaneous klebsiella pneumoniae outbreaks resistant to multiple antibiotics are reported. the closely related strains were distinguished by comparing the zone diameters obtained by disk diffusion susceptibility testing but not by interpretations of susceptible, resistant, or intermediate. similar conclusions were made when minimal inhibitory concentrations were considered. the separation was subsequently confirmed by capsular serotyping into types 2 and 30. the data presented suggest that ... | 1978 | 370152 |
| thermosensitive h1 plasmids determining citrate utilization. | twelve thermosensitive h1 plasmids from strains of salmonella typhi that had caused outbreaks of chloramphenicol-resistant typhoid fever in vietnam, thailand and india mediated citrate utilization (cit+) in a prototrophic escherichia coli k12 strain but not in the s. typhi strains from which they were derived. four h1 plasmids from a similar outbreak in mexico differed from the far eastern plasmids in not mediating citrate utlization but in mediating mercury resistance. h1 plasmids resembling th ... | 1978 | 370344 |
| epidemiologic and bacteriologic evaluation of neonatal necrotizing enterocolitis. | the incidence of necrotizing enterocolitis (nec) in our neonatal unit has varied from 4.7% to zero to 4.4% during three time periods. simultaneously, significant changes have occurred in the spectrum of bacterial species in the gastrointestinal tract of unaffected infants in the same unit. during the first period of increased attack rate, 82% of gastric and 88% of fecal enterobacteriaceae were e. coli and k. pneumoniae. when the attack rate decreased the frequencies were 11% (gastric) and 47% (f ... | 1979 | 370356 |
| [basic and clinical examinations of cs-1170 in pediatrics (author's transl)]. | 1. cs-1170 was administered for the purpose of prophylaxis during cardiac catheterization in patients with heart disease, and its blood levels were measured. 2. the mean blood level (moni-trol i standard) after one intravenous shot of 20 mg/kg was 53.6 mcg/ml in catheterized children aged below 6 and 66.9 mcg/ml in catheterized children aged above 10 at 30 minutes, and 1.95 mcg/ml and 5.2 mcg/ml respectively at 6 hours. 3. the mean half life of the blood level was 1.09 hours in catheterized chil ... | 1979 | 370423 |
| septicemia in children with cancer. | because of the persistently high mortality from sepsis in cancer patients, a retrospective study was designed to identify the causative organisms and to determine the factors affecting the outcome of sepsis. a total of 84 episodes of septicemia in 61 children with cancer were studied. the more frequently isolated organisms were: staphylococcus aureus (21.4%); escherichia coli (18%); klebsiella (7.1%); pseudomonas (6%); and bacteroides fragilis (6%). other isolates included proteus, serratia, aci ... | 1979 | 371000 |
| [a new method for evaluation of beta-lactamase production of resistant enterobacteriaceae strains (author's transl)]. | resistant strains of enterobacteriaceae were investigated with a chemical and microbiological test on beta-lactamase activity. the chemical method was needed as screening-test basing on the enzymatic hydrolysis of the chromogenic cephalosporin compound 87/312. the microbiological test is a modified cup plate method using staph. aureus sg 511 as sensitive test strain for penicillins and cephalosporins. in one of the two cups of the blood agar plate 20 microliter of the beta-lactam antibiotic, in ... | 1978 | 371259 |
| [gibbs free energy in periodic enterobacterial cultures]. | the authors present the results of study of the gibbs' free energy (--delta g) output in periodic cultures of nonpathogenic and enteropathogenic escherichia, shigellae, salmonellae, proteus, serratia, and klebsiellae in the hydrolysate broth in a special twelve--chamber cultivator. graphic expression--deltag = f(n) permitted to reveal differences in the energy characteristics of individual enterobacteria genera and species. it is supposed that such studies could be useful in the choice of redox ... | 1978 | 371306 |
| bacteriocin typing of serratia marcescens. a simplified system. | the authors describe a simplified system for the detection of bacteriocin production by serratia marcescens with the use of six indicator strains, which include escherichia coli, klebsiella pneumoniae, citrobacter diversus, enterobacter aerogenes (two strains), and serratia rubidaea grown on arabinose minimal medium plates. of the 64 possible bacteriocin types, 11 were observed; 66% of the isolates tested were found to be one of three types. occasionally more than one bacteriocin type was observ ... | 1979 | 371382 |
| endotoxin in germfree, gnotobiotic, or conventional-flora sprague-dawley rats. | the limulus assay for bacterial endotoxin was performed on serum and (or) plasma from animals monoassociated with clostridium species, staphylococcus aureus, escherichia coli, proteus mirabilis, enterobacter agglomerans, bacteroides fragilis, klebsiella pneumoniae, or candida albicans. plasma from animals monoassociated with the gram-negative bacteria or c. albicans consistently showed a positive limulus test while conventional-flora controls, germfree rats, and gnotobiotic animals monoassociate ... | 1978 | 371771 |