| fatal non-thrombotic pulmonary embolization in a patient with undiagnosed factitious disorder. | factitious fever is extremely challenging to diagnose in patients with complicated chronic medical problems, and represents as much as 10% of fevers of unknown origin. factitious fever caused by self-injecting oral medications through indwelling central catheters is a diagnostic challenge. | 2015 | 26164684 |
| a retrospective international study on primary extranodal marginal zone lymphoma of the lung (balt lymphoma) on behalf of international extranodal lymphoma study group (ielsg). | primary lymphoma of the lung is a rare entity. clinical features, optimal treatment, role of surgery and outcomes are not well defined, and the follow-up is variable in published data. clinical data of 205 patients who were confirmed to have bronchus mucosa-associated lymphoid tissue lymphoma from december 1986 to december 2011 in 17 different centres worldwide were evaluated. fifty-five per cent of the patients were female. the median age at diagnosis was 62 (range 28-88) years. only 9% had a h ... | 2016 | 26152851 |
| achromobacter xylosoxidans infection in an adult cystic fibrosis unit in madrid. | achromobacter xylosoxidans is an emerging pathogen in cystic fibrosis (cf). although the rate of colonization by this microorganism is variable, prevalence is increasing in cf units. | 2016 | 26139304 |
| hydrogen bonding of the dissociated histidine ligand is not required for formation of a proximal no adduct in cytochrome c'. | cytochromes c', that occur in methanotrophic, denitrifying and photosynthetic bacteria, form unusual proximal penta-coordinate no complexes via a hexa-coordinate distal no intermediate. their no binding properties are similar to those of the eukaryotic no sensor, soluble guanylate cyclase, for which they provide a valuable structural model. previous studies suggested that hydrogen bonding between the displaced proximal histidine (his120) ligand (following its dissociation from heme due to trans ... | 2015 | 26100643 |
| enhanced chrysene degradation by a mixed culture biorem-cgbd using response surface design. | degradation of chrysene, a four ringed highly carcinogenic polycyclic aromatic hydrocarbon (pah) has been demonstrated by bacterial mixed culture biorem-cgbd comprising achromobacter xylosoxidans, pseudomonas sp. and sphingomonas sp., isolated from crude oil polluted saline sites at bhavnagar coast, gujarat, india. a full factorial central composite design (ccd) using response surface methodology (rsm) was applied to construct response surfaces, predicting 41.93% of maximum chrysene degradation ... | 2015 | 26040022 |
| success with extended-infusion meropenem after recurrence of baclofen pump-related achromobacter xylosoxidans meningitis in an adolescent. | a 13-year-old female experienced a recurrence of baclofen pump-related central nervous system (cns) infection caused by achromobacter, despite absence of retained foreign material. due to the failure of meropenem (120 mg/kg/d in divided doses every 8 hours and infused over 30 minutes) in the initial infection, the dose was infused over 4 hours during the recurrence. meropenem is an antibiotic for which efficacy is time dependent, and 4-hour versus 30-minute infusions have been shown to prolong t ... | 2015 | 26033796 |
| achromobacter xylosoxidans bacteremia and cellulitis: a report of a case. | achromobacter xylosoxidans is a rare, opportunistic infection most commonly encountered in immunocompromised patients during hospitalization. primary uncomplicated bacteremia, catheter-associated infections, and pneumonia have been reported as the most common clinical presentations; skin and soft tissue infections from a. xylosoxidans are rare. we describe a case of a. xylosoxidans presenting as cellulitis and bacteremia in an immunocompromised patient. | 2016 | 25973735 |
| resonance raman spectra of five-coordinate heme-nitrosyl cytochromes c': effect of the proximal heme-no environment. | five-coordinate heme nitrosyl complexes (5cno) underpin biological heme-no signal transduction. bacterial cytochromes c' are some of the few structurally characterized 5cno proteins, exhibiting a distal to proximal 5cno transition of relevance to no sensing. establishing how 5cno coordination (distal vs proximal) depends on the heme environment is important for understanding this process. recent 5cno crystal structures of alcaligenes xylosoxidans cytochrome c' (axcp) and shewanella frigidimarina ... | 2015 | 25961377 |
| hexacyclopeptides secreted by an endophytic fungus fusarium solani n06 act as crosstalk molecules in narcissus tazetta. | the basis of chemical crosstalk in plants and associated endophytes lies in certain so-called communication molecules that are responsible for plant-microbe and microbe-microbe interactions. consequently, elucidating the factors that affect the nature, distribution, and amount of these molecules and how they impact the interaction among endophytes and associated organisms is essential to understand the true potential of endophytes. in the present study, we report the discovery of nine hexacyclop ... | 2015 | 25958995 |
| emerging bacterial pathogens and changing concepts of bacterial pathogenesis in cystic fibrosis. | chronic suppurative lower airway infection is a hallmark feature of cystic fibrosis (cf). decades of experience in clinical microbiology have enabled the development of improved technologies and approaches for the cultivation and identification of microorganisms from sputum. it is increasingly apparent that the microbial constituents of the lower airways in cf exist in a dynamic state. indeed, while changes in prevalence of various pathogens occur through ageing, differences exist in successive ... | 2015 | 25881770 |
| pan-resistant achromobacter xylosoxidans and stenotrophomonas maltophilia infection in cystic fibrosis does not reduce survival after lung transplantation. | the number of cystic fibrosis (cf) patients undergoing lung transplantation continues to grow, as does the prevalence of multidrug-resistant (mdr) gram-negative rods. however, the posttransplant survival of patients with mdr pathogens, specifically pan-resistant achromobacter xylosoxidans and stenotrophomonas maltophilia, is poorly characterized. | 2015 | 25856407 |
| biotic inactivation of the pseudomonas aeruginosa quinolone signal molecule. | in pseudomonas aeruginosa, quorum sensing (qs) regulates the production of secondary metabolites, many of which are antimicrobials that impact on polymicrobial community composition. consequently, quenching qs modulates the environmental impact of p. aeruginosa. to identify bacteria capable of inactivating the qs signal molecule 2-heptyl-3-hydroxy-4(1h)-quinolone (pqs), a minimal medium containing pqs as the sole carbon source was used to enrich a malaysian rainforest soil sample. this yielded a ... | 2015 | 25809238 |
| intrapatient diversity of achromobacter spp. involved in chronic colonization of cystic fibrosis airways. | achromobacter spp. are increasingly identified in cystic fibrosis (cf) patients and their ability to persistently colonize the cf respiratory tract (cfrt) suggests that achromobacter species possess adaptive characteristics. we studied genome dynamics in 118 isolates recovered from 13 patients with achromobacter chronic colonization (5-26 isolates per patient recovered over 13-61 months). isolates were identified to species level by nrda gene sequencing, subjected to pulsed-field gel electrophor ... | 2015 | 25791931 |
| efficacy of antimicrobials against biofilms of achromobacter and pseudomonas. | achromobacter xylosoxidans and pseudomonas aeruginosa biofilms can develop in ophthalmic products and accessories such as contact lens cases, leading to the development of ocular infections. this study evaluated the efficacy of the antimicrobials polyaminopropyl biguanide (papb) and benzalkonium chloride (bak) against a. xylosoxidans and p. aeruginosa biofilms. | 2015 | 25785528 |
| isolation of multiple drug-resistant enteric bacteria from feces of wild western lowland gorilla (gorilla gorilla gorilla) in gabon. | prevalence of drug-resistant bacteria in wildlife can reveal the actual level of anthropological burden on the wildlife. in this study, we isolated two multiple drug-resistant strains, gg6-2 and gg6-1-1, from 27 fresh feces of wild western lowland gorillas in moukalaba-doudou national park, gabon. isolates were identified as achromobacter xylosoxidans and providencia sp., respectively. minimum inhibitory concentrations of the following 12 drugs-ampicillin (abpc), cefazolin (cez), cefotaxime (ctx ... | 2015 | 25649412 |
| stenotrophomonas, achromobacter, and nonmelioid burkholderia species: antimicrobial resistance and therapeutic strategies. | stenotrophomonas maltophilia, achromobacter xylosoxidans, and nonmelioid burkholderia species, namely, burkholderia cepacia complex, collectively are a group of troublesome nonfermenters. although not inherently virulent organisms, these environmental gram negatives can complicate treatment in those who are immunocompromised, critically ill in the intensive care unit and those patients with suppurative lung disease, such as cystic fibrosis. through a range of intrinsic antimicrobial resistance m ... | 2015 | 25643274 |
| development of a growth-dependent selection system for identification of l-threonine aldolases. | threonine aldolases (tas) are useful enzymes for the synthesis of β-hydroxy-α-amino acids due to their capability to catalyze asymmetric aldol reactions. starting from two prochiral compounds, an aldehyde and glycine, two chiral stereocenters were formed in a single step via c-c bond formation. owing to poor diastereoselectivity and low activity, the enzymatic synthesis of β-hydroxy-α-amino acids by tas is still a challenge. for identification of new tas, a growth-dependent selection system in p ... | 2015 | 25616526 |
| denitrification by cystic fibrosis pathogens - stenotrophomonas maltophilia is dormant in sputum. | chronic pseudomonas aeruginosa lung infection is the most severe complication for cystic fibrosis (cf) patients. infected endobronchial mucus of cf patients contains anaerobic zones mainly due to the respiratory burst of polymorphonuclear leukocytes. we have recently demonstrated ongoing denitrification in sputum from patients infected with p. aeruginosa. therefore we aimed to investigate, whether the pathogenicity of several known cf pathogens is correlated to their ability to perform denitrifi ... | 2015 | 25441256 |
| imp-1 encoded by a novel tn402-like class 1 integron in clinical achromobacter xylosoxidans, china. | achromobacter xylosoxidans strain a22732 is isolated from a pneumonia patient in china and produces carbapenemases oxa-114e and imp-1, which are encoded by chromosome and plasmid, respectively, and confer resistance to multiple ß-lactam antibiotics including carbapenems. the blaimp-1 gene together with aaca7 and orfe is captured by a novel tn402-like class 1 integron in a conjugative incp-1ß plasmid. in addition to the intrinsic integron promoter pcw, there is still a blaimp-1 gene cassette-spec ... | 2014 | 25428613 |
| chemotaxis-based endosulfan biotransformation: enrichment and isolation of endosulfan-degrading bacteria. | the study was conducted to isolate endosulfan biotransforming or biodegrading microbes based on chemotaxis. pseudomonas aeruginosa strain kkc3, ochrobactrum sp. strain kkc4, achromobacter xylosoxidans strain kkc6 and bacillus megaterium kkc7 were isolated based on their migration towards endosulfan in a soil column. out of the four bacteria, b. megaterium converted endosulfan into toxic metabolite endosulfan sulphate, while the other three bacteria followed the non-toxic endosulfan diol pathway. ... | 2014 | 25409584 |
| elucidation of fluoranthene degradative characteristics in a newly isolated achromobacter xylosoxidans dn002. | strain dn002 isolated from petroleum-contaminated soil was identified as achromobacter xylosoxidans based on morphological and biochemical properties and 16s rrna phylogeny, and investigated for its potential to utilize numerous polycyclic aromatic hydrocarbons (pahs) such as fluoranthene and pyrene as sole carbon and energy resource. biodegradation studies showed that 500 mg(·)l(-1)fluranthene was degraded to 35.6 ± 0.3 mg(·)l(-1) by dn002 after 14 days incubation. during fluoranthene biodegrad ... | 2015 | 25381650 |
| interaction between atypical microorganisms and e. coli in catheter-associated urinary tract biofilms. | most biofilms involved in catheter-associated urinary tract infections (cautis) are polymicrobial, with disease causing (eg escherichia coli) and atypical microorganisms (eg delftia tsuruhatensis) frequently inhabiting the same catheter. nevertheless, there is a lack of knowledge about the role of atypical microorganisms. here, single and dual-species biofilms consisting of e. coli and atypical bacteria (d. tsuruhatensis and achromobacter xylosoxidans), were evaluated. all species were good biof ... | 2014 | 25184430 |
| achromobacter xylosoxidans in two haemodialysis patients. | | 2014 | 25036074 |
| scleral buckle infection with alcaligenes xylosoxidans. | we describe a rare case of extraocular inflammation secondary to scleral buckle infection with alcaligenes xylosoxidans. a 60-year-old female with a history of retinal detachment repair with open-book technique of scleral buckling presented with purulent discharge and irritation in the right eye that had begun 4 weeks earlier and had been treated ineffectively at another hospital. conjunctival erosion with exposure of the scleral buckle was noted. the scleral buckle was removed and cultured. the ... | 2014 | 25005211 |
| pulmonary infection caused by achromobacter xylosoxidans in a patient with carcinoma of epiglottis: a rare case. | achromobacter xylosoxidans is an aerobic, motile, oxidase and catalase positive, non-fermenting, gram negative bacillus. it is an opportunistic pathogen which is responsible for various nosocomial and community-acquired infections. however, there are only very few reports of pulmonary infections caused by this bacterium in cancer patients. we are presenting a case of a patient with carcinoma of epiglottis, who developed pulmonary infection caused by achromobacter xylosoxidans. according to the a ... | 2014 | 24995184 |
| resolution of concomitant achromobacter xylosoxidans burn wound infection without adjustment of antimicrobial therapy. | achromobacter xylosoxidans is part of an emerging group of gram negative bacterial infections with potentially severe sequelae, especially in the immunocompromised population such as burn patients. while antimicrobial therapy for patients with a. xylosoxidans bacteremia has been reported, the literature is scarce with regard to treatment in patients with positive tissue cultures only. herein, we report our institution's experience with such a case and a brief review of the current literature on ... | 2014 | 24987220 |
| maldi-tof: a useful tool for laboratory identification of uncommon glucose non-fermenting gram-negative bacteria associated with cystic fibrosis. | the predisposition of patients with cystic fibrosis (cf) for recurrent pulmonary infections can result in poor prognosis of the disease. although the clinical significance in cf of micro-organisms, such as staphylococcus aureus, haemophilus influenzae and pseudomonas aeruginosa, is well established, the implication of uncommon glucose non-fermenting gram-negative bacilli (ugnf-gnb) in respiratory samples from cf patients is still unclear. because of limitations of traditional methods used in mos ... | 2014 | 24980571 |
| intracardiac abscess with cutaneous fistula secondary to ventricular septal defect repair simulating sternal wound infection. | cutaneous fistula as a clinical presentation of intracardiac abscess of the right side is such an unusual occurrence that it has not until now been reported in the english-language medical literature. we present a rare case of right-sided infective endocarditis caused by achromobacter xylosoxidans in which recurrent infection presented as sternal wound discharge. the infection was found to have an intracardiac origin and was successfully managed by radical débridement on cardiopulmonary bypass. | 2014 | 24955054 |
| arteriovenous fistula-related bacteremia caused by achromobacter xylosoxidans in a uremic patient. | | 2015 | 24856428 |
| fingerprinting redox and ligand states in haemprotein crystal structures using resonance raman spectroscopy. | it is crucial to assign the correct redox and ligand states to crystal structures of proteins with an active redox centre to gain valid functional information and prevent the misinterpretation of structures. single-crystal spectroscopies, particularly when applied in situ at macromolecular crystallography beamlines, allow spectroscopic investigations of redox and ligand states and the identification of reaction intermediates in protein crystals during the collection of structural data. single-cr ... | 2014 | 24816098 |
| altered bacterial profiles in saliva from adults with caries lesions: a case-cohort study. | the aim of this study was to learn whether presence of caries in an adult population was associated with a salivary bacterial profile different from that of individuals without untreated caries. stimulated saliva samples from 621 participants of the danish health examination survey were analyzed using the human oral microbe identification microarray technology. samples from 174 individuals with dental caries and 447 from a control cohort were compared using frequency and levels of identified bac ... | 2014 | 24643218 |
| putative p1b-type atpase from the bacterium achromobacter xylosoxidans a8 alters pb2+/zn2+/cd2+-resistance and accumulation in saccharomyces cerevisiae. | pbta, a putative p(1b)-type atpase from the gram-negative soil bacterium achromobacter xylosoxidans a8 responsible for pb(2+)/zn(2+)/cd(2+)-resistance in escherichia coli, was heterologously expressed in saccharomyces cerevisiae. when present in zn(2+)- and pb(2+)/cd(2+)-hypersensitive s. cerevisiae strains cm137 and dty168, respectively, pbta was able to restore zn(2+)- and pb(2+)-resistant phenotype. at the same time, the increase of pb, zn, and cd accumulation in yeast was observed. however, ... | 2014 | 24491492 |
| role of thiobacillus thioparus in the biodegradation of carbon disulfide in a biofilter packed with a recycled organic pelletized material. | this study reports the biodegradation of carbon disulfide (cs2) in air biofilters packed with a pelletized mixture of composted manure and sawdust. experiments were carried out in two lab-scale (1.2 l) biofiltration units. biofilter b was seeded with activated sludge enriched previously on cs2-degrading biomass under batch conditions, while biofilter a was left as a negative inoculation control. this inoculum was characterized by an acidic ph and sulfate accumulation, and contained achromobacter ... | 2014 | 24469405 |
| first genome sequences of achromobacter phages reveal new members of the n4 family. | multi-resistant achromobacter xylosoxidans has been recognized as an emerging pathogen causing nosocomially acquired infections during the last years. phages as natural opponents could be an alternative to fight such infections. bacteriophages against this opportunistic pathogen were isolated in a recent study. this study shows a molecular analysis of two podoviruses and reveals first insights into the genomic structure of achromobacter phages so far. | 2014 | 24468270 |
| l5-s1 achromobacter xylosoxidans infection secondary to oxygen-ozone therapy for the treatment of lumbosacral disc herniation: a case report and review of the literature. | case report and literature review. | 2014 | 24384664 |
| enhanced biodegradation of total polycyclic aromatic hydrocarbons (tpahs) by marine halotolerant achromobacter xylosoxidans using triton x-100 and β-cyclodextrin--a microcosm approach. | ability of achromobacter xylosoxidans, a chrysene degrading marine halotolerant bacterium to degrade polycyclic aromatic hydrocarbons (pahs) using a cost effective laboratory microcosm approach, was investigated. effect of variables as chrysene, glucose as a co-substrate, triton x-100 as a non-ionic surfactant and β-cyclodextrin as a pahs solubilizer was examined on degradation of low molecular weight (lmw) and high molecular weight (hmw) pahs. a total of eleven pahs detected from polluted salin ... | 2014 | 24382467 |
| prevalence of achromobacter xylosoxidans in pulmonary mucosa-associated lymphoid tissue lymphoma in different regions of europe. | extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (malt lymphoma) comprises 7-8% of b-cell lymphomas and commonly originates from a background of long-standing chronic inflammation. an association with distinct bacteria species has been confirmed for several anatomical sites of malt lymphoma. for pulmonary malt lymphoma, however, a clear link with an infectious agent or autoimmune disorder has not yet been reported. using a 16s rrna gene-based approach, we have recently iden ... | 2014 | 24372375 |
| skin and soft tissue infection caused by achromobacter xylosoxidans: report of 14 cases. | skin and soft tissue infections (sstis) caused by achromobacter xylosoxidans are very infrequent. the aim of the present study was to investigate the clinical and microbiological characteristics of this infection. | 2014 | 24325336 |
| the influence of bioaugmentation and biosurfactant addition on bioremediation efficiency of diesel-oil contaminated soil: feasibility during field studies. | the study focused on assessing the influence of bioaugmentation and addition of rhamnolipids on diesel oil biodegradation efficiency during field studies. initial laboratory studies (measurement of emitted co2 and dehydrogenase activity) were carried out in order to select the consortium for bioaugmentation as well as to evaluate the most appropriate concentration of rhamnolipids. the selected consortium consisted of following bacterial taxa: aeromonas hydrophila, alcaligenes xylosoxidans, gordo ... | 2014 | 24291585 |
| antibody response to achromobacter xylosoxidans during hiv infection is associated with lower cd4 levels and increased lymphocyte activation. | inflammation during hiv infection is associated with worse disease outcomes and progression. many mechanisms have been indicted, including hiv itself, coinfections, and gut microbial translocation. concerning microbial translocation, we hypothesized that adaptive immune responses to a specific bacterial species known to be present in gut-associated lymphoid tissue are higher among hiv-infected individuals than among hiv-uninfected controls and are associated with t cell activation and lower cd4 ... | 2014 | 24173027 |
| endophthalmitis caused by achromobacter xylosoxidans after cataract surgery. | to report achromobacter xylosoxidans as a cause of both acute-onset and delayed-onset postoperative endophthalmitis after cataract surgery. | 2014 | 24150240 |
| characterization of pbt genes conferring increased pb2+ and cd2+ tolerance upon achromobacter xylosoxidans a8. | the cluster of pbttfyrabc genes is carried by plasmid pa81. its elimination from achromobacter xylosoxidans a8 resulted in increased sensitivity towards pb(2+) and cd(2+). predicted pbttrabc products share strong similarities with pb(2+) uptake transporter pbrt, transcriptional regulator pbrr, metal efflux p1-atpases pbra and cada, undecaprenyl pyrophosphatase pbrb and its signal peptidase pbrc from cupriavidus metallidurans ch34. expression of pbtabc or pbta in a metal-sensitive escherichia col ... | 2013 | 24125695 |
| bioremediation assessment of diesel-biodiesel-contaminated soil using an alternative bioaugmentation strategy. | this study investigated the effectiveness of successive bioaugmentation, conventional bioaugmentation, and biostimulation of biodegradation of b10 in soil. in addition, the structure of the soil microbial community was assessed by polymerase chain reaction-denaturing gradient gel electrophoresis. the consortium was inoculated on the initial and the 11th day of incubation for successive bioaugmentation and only on the initial day for bioaugmentation and conventional bioaugmentation. the experimen ... | 2014 | 24091525 |
| gates and binding pockets for nitric oxide with cytochrome c', according to molecular dynamics. | random-acceleration molecular-dynamics (ramd) simulations with models of homodimeric 6-ligated distal-no and 5-ligated proximal-no cytochrome c' complexes, in tip3 h2 o, showed two distinct, non-intercommunicating worlds. in the framework of a long cavity formed by four protein helices with heme at one extremity, no was observed to follow different pathways with the two complexes to reach the solvent. with the 6-ligated complex, no was observed to progress by exploiting protein internal channels ... | 2013 | 24078591 |
| bacterial sinusitis can be a focus for initial lung colonisation and chronic lung infection in patients with cystic fibrosis. | a major purpose of treating patients with cystic fibrosis (cf) is to prevent or delay chronic lung infections with cf-pathogenic gram-negative bacteria. in the intermittent stage, bacteria can usually be eradicated from the lungs with antibiotics, but following eradication, the next lung colonisations often occur with bacteria of identical genotype. this may be due to re-colonisation from the patient's paranasal sinuses. in our study, we found that approximately two-thirds of cf patients having ... | 2013 | 24064077 |
| achromobacter xylosoxidans keratitis masquerading as recurrent erosion after lasik. | to describe the clinical stages and management of achromobacter xylosoxidans keratitis with post-lasik epithelial ingrowth in two patients. | 2013 | 24063345 |
| achromobacter xylosoxidans induced bronchiolitis obliterans in cystic fibrosis. | we report a 12-year-old boy with progressive bronchiolitis obliterans caused by achromobacter xylosoxidans (ax) colonization after liver transplantation, resulting in a steep decline in lung function. | 2014 | 24039244 |
| achromobacter xylosoxidans meningitis in an immunosuppressed patient. | | 2014 | 23970185 |
| characterization of plasmid pax22, encoding vim-1 metallo-β-lactamase, reveals a new putative mechanism of in70 integron mobilization. | vim-type enzymes are among the most widespread acquired metallo-β-lactamases among gram-negative pathogens. integron in70 is a class 1 integron that has emerged as a successful genetic support for blavim-1 (one of the most prevalent blavim allelic variants) in gram-negative non-fermenters, and is usually chromosome borne. the objective of this study was to characterize plasmid pax22 from achromobacter xylosoxidans ax22, which represents the only in70-harbouring plasmid known so far, to gather in ... | 2014 | 23928025 |
| [bacteremia and pneumonia due to alcaligenes xylosoxidans in a immunocompetent patient]. | | 2013 | 23877784 |
| perinephric abscess due to achromobacter xylosoxidans following de-roofing of renal cyst. | | 2013 | 23859686 |
| distribution of allelic variants of the chromosomal gene bla oxa-114-like in achromobacter xylosoxidans clinical isolates. | achromobacter xylosoxidans is increasingly being documented in cystic fibrosis patients. the bla(oxa-114) gene has been recognized as a naturally occurring chromosomal gene, exhibiting different allelic variants. in the population under study, the bla(oxa-114)-like gene was found in 19/19 non-epidemiological-related clinical isolates of a. xylosoxidans with ten different alleles including 1 novel oxa-114 variant. | 2013 | 23771548 |
| achromobacter species in cystic fibrosis: cross-infection caused by indirect patient-to-patient contact. | achromobacter species leads to chronic infection in an increasing number of cf patients. we report 2 cases of achromobacter ruhlandii cross-infection between patients after well-described indirect contact. | 2013 | 23769270 |
| bacteremia due to achromobacter xylosoxidans in neonates: clinical features and outcome. | we report an outbreak of achromobacter xylosoxidans at a neonatal intensive care unit. we aimed to present clinical, laboratory and treatment data of the patients. | 2013 | 23742802 |
| early treatment with inhaled antibiotics postpones next occurrence of achromobacter in cystic fibrosis. | in this nationwide retrospective study, we analysed species distribution, antimicrobial susceptibility and time to next occurrence of achromobacter in danish cystic fibrosis (cf) patients from 2000 to 2011. | 2013 | 23727271 |
| evaluation of colistin susceptibility in multidrug-resistant clinical isolates from cystic fibrosis, france. | the emergence of multidrug-resistant (mdr) bacteria in cystic fibrosis (cf) patients has led to the use of colistin drug and the emergence of colistin-resistant gram-negative bacteria. the aim of this study was to compare the disk diffusion and etest methods for colistin susceptibility testing on mdr bacteria associated with cf from marseille, france. forty-nine mdr clinical isolates (27 stenotrophomonas maltophilia, 22 achromobacter xylosoxidans) were used in this study. disk diffusion and etes ... | 2013 | 23719852 |
| construction of a plant-microbe phytoremediation system: combination of vetiver grass with a functional endophytic bacterium, achromobacter xylosoxidans f3b, for aromatic pollutants removal. | the endophytic bacterial strain achromobacter xylosoxidans f3b, which was able to utilize aromatic compounds as a sole carbon source, was inoculated into vetiver grass in this study. a real-time pcr detection method has been developed for confirming the stability of f3b in plants and dgge profiles were conducted for examining the diversity of endophytes during the remediation process. these results showed that the endophytic bacteria strain f3b could maintain a stable population in plant roots w ... | 2013 | 23591084 |
| [bacterial isolates from respiratory samples of pediatric patients with cystic fibrosis and their distribution by ages]. | the bacterial isolates from respiratory samples of 50 pediatric patients with cystic fibrosis, their distribution by ages and antimicrobial resistance pattern as well as the intermittence of isolations and coinfections, were investigated. staphylococcus aureus was isolated in 72 % of patients, followed by pseudomonas aeruginosa (58 %), haemophilus. influenzae (56 %), and the burkholderia cepacia complex (12 %). the frequency of resistance of p. aeruginosa isolates to β-lactam antibiotics was low ... | 2013 | 23560788 |
| bacterial strains isolated from pcb-contaminated sediments and their use for bioaugmentation strategy in microcosms. | this study was focused on the characterization of 15 bacterial strains isolated from long-term pcb-contaminated sediment located at the strážsky canal in eastern part of slovakia, in the surroundings of a former pcb producer. pcb-degrading strains were isolated and identified as microbacterium oleivorans, stenotrophomonas maltophilia, brevibacterium sp., ochrobactrum anthropi, pseudomonas mandelii, rhodococcus sp., achromobacter xylosoxidans, stenotrophomonas sp., ochrobactrum sp., pseudomonas a ... | 2014 | 23553615 |
| alcaligenes xylosoxidans endocarditis of a prosthetic valve and pacemaker in a 62-year-old woman. | the bacterium alcaligenes xylosoxidans is known to cause several nosocomial infections; however, it rarely causes endocarditis, which has a very high mortality rate. early isolation of the infection source and prompt identification of the patient's antibiotic sensitivities are paramount if the infection is to be treated adequately. we present what is apparently only the second documented case of the successful eradication of bioprosthetic valve endocarditis that was caused by pacemaker lead infe ... | 2013 | 23466992 |
| respiratory bacterial infections in cystic fibrosis. | bacterial respiratory infections are the main cause of morbidity and mortality in patients with cystic fibrosis (cf). pseudomonas aeruginosa remains the main pathogen in adults, but other gram-negative bacteria such as achromobacter xylosoxidans and stenotrophomonas maltophilia as well as nontuberculous mycobacteria have been shown to play an important role in the lung disease. the purpose of this review is to summarize the knowledge on disease and treatment of infection with cf-related pathogen ... | 2013 | 23449384 |
| efficacy of disinfectants against naturally occurring and artificially cultivated bacteria. | naturally occurring bacteria, is exist in nature, and is never cultivated on conventional culture medium. we evaluated the efficacy of disinfectants against naturally occurring bacteria in in-use cotton balls soaked in 0.02% benzalkonium chloride solution which had been used to disinfect the genital area by patients undergoing self-catheterization at home and the same bacteria subcultured on nutrient broth (artificially cultivated bacteria). the colony forming units (cfu) of naturally occurring ... | 2013 | 23449324 |
| the effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis. | most patients with cystic fibrosis (cf) have chronic rhinosinusitis; their sinuses are often colonized with bacteria that can initiate and maintain deleterious pulmonary infections. theoretically, eradication of the sinus bacteria should reduce the frequency of lung infections and thereby reduce pulmonary morbidity. this article addressed whether bacteria in cf sinuses are eligible for eradication by sinus surgery and postoperative treatment. | 2013 | 23406585 |
| picosecond binding of the his ligand to four-coordinate heme in cytochrome c': a one-way gate for releasing proximal no. | we provide a direct demonstration of a "kinetic trap" mechanism in the proximal 5-coordinate heme-nitrosyl complex (5c-no) of cytochrome c' from alcaligenes xylosoxidans (axcp) in which picosecond rebinding of the endogenous his ligand following heme-no dissociation acts as a one-way gate for the release of proximal no into solution. this demonstration is based upon picosecond transient absorption changes following no photodissociation of the proximal 5c-no axcp complex. we have determined the a ... | 2013 | 23373628 |
| [a case obstructive jaundice and liver abscess caused by achromobacter xylosoxidans]. | | 2012 | 23320273 |
| [case report: respiratory infection due to alcaligenes xylosoxidans in a patient with mounier-kuhn syndrome]. | mounier-kuhn syndrome is a rare entity characterized by abnormal dilatation of the trachea and main bronchi (tracheobronchomegaly). alcaligenes xylosoxidans is a non fermenting gram-negative pathogen common in extra-and intra-hospital environment, which may be related to immunosuppression states. we describe the case of a 75 years old male, ex-smoker with moderate functional obstruction, chronic respiratory failure and chronic colonization by pseudomonas aeuriginosa. he had an infectious exacerb ... | 2012 | 23282506 |
| community acquired bilateral upper lobe pneumonia with acute adrenal insufficiency: a new face of achromobacter xylosoxidans. | achromobacter xylosoxidans is an uncommon pathogen of low virulence known to cause serious nosocomial infection in the immunocompromised. its inherent multi-drug resistance makes treatment difficult. community-acquired infections are rare despite its ubiquitous existence. we present a 50-year-old immunocompetent woman who presented with one-month history of coughing with expectoration who was subsequently diagnosed with bilateral upper lobe pneumonia and acute adrenal insufficiency. achromobacte ... | 2012 | 23173016 |
| identification and distribution of achromobacter species in cystic fibrosis. | we recently described a multilocus sequence typing scheme for achromobacter that identified several novel species in this genus. | 2013 | 23141756 |
| [achromobacter xylosoxidans]. | | 2012 | 23096549 |
| innate aminoglycoside resistance of achromobacter xylosoxidans is due to axyxy-oprz, an rnd-type multidrug efflux pump. | achromobacter xylosoxidans is an innately multidrug-resistant pathogen which is emerging in cystic fibrosis (cf) patients. we characterized a new resistance-nodulation-cell division (rnd)-type multidrug efflux pump, axyxy-oprz. this system is responsible for the intrinsic high-level resistance of a. xylosoxidans to aminoglycosides (tobramycin, amikacin, and gentamicin). furthermore, it can extrude cefepime, carbapenems, some fluoroquinolones, tetracyclines, and erythromycin. some of the axyxy-op ... | 2013 | 23089757 |
| epidemiology and resistance of achromobacter xylosoxidans from cystic fibrosis patients in dijon, burgundy: first french data. | achromobacter xylosoxidans is an emerging pathogen in cystic fibrosis (cf) patients recognised as causal agent of inflammation. the prevalence of infection or colonisation is variable among cf centres. we report here the first epidemiological data about a. xylosoxidans in a french cf centre: dijon, burgundy. | 2013 | 22944724 |
| achromobacter xylosoxidans: an emerging pathogen carrying different elements involved in horizontal genetic transfer. | in the last few years, numerous cases of multidrug-resistant achromobacter xylosoxidans infections have been documented in immunocompromised and cystic fibrosis patients. to gain insights into the molecular mechanisms and mobile elements related to multidrug resistance in this bacterium, we studied 24 non-epidemiological a. xylosoxidans clinical isolates from argentina. specific primers for plasmids, transposons, insertion sequences, bla(ampc), inti1, and inti2 genes were used in pcr reactions. ... | 2012 | 22926720 |
| microbial contamination of a disinfectant-soaked unwoven cleaning cloth. | in december 2009, a 76-year-old male patient developed pneumonia due to burkholderia cepacia whilst in an intensive care unit at a japanese university hospital. during the subsequent environmental investigation to find the source, b. cepacia with an identical dna type was found in his denture storage solution. open packets of unwoven rayon cloths soaked in 0.2% alkyldiaminoethylglycine hydrochloride, used for environmental cleaning, were shown to be contaminated with b. cepacia, alcaligenes xylo ... | 2012 | 22854353 |
| 1-aminocyclopropane-1-carboxylic acid (acc) deaminase-containing rhizobacteria protect ocimum sanctum plants during waterlogging stress via reduced ethylene generation. | ocimum sanctum grown as rain-fed crop, is known to be poorly adapted to waterlogged conditions. many a times the crop suffers extreme damages because of anoxia and excessive ethylene generation due to waterlogging conditions present under heavy rain. the usefulness of 1-aminocyclopropane-1-carboxylic acid (acc) deaminase-containing plant growth promoting rhizobacteria was investigated under waterlogging stress. the comparison of herb yield and stress induced biochemical changes of waterlogged an ... | 2012 | 22846334 |
| continuous ambulatory peritoneal dialysis-related peritonitis in an uremic outpatient: achromobacter xylosoxidans. | | 2012 | 22814104 |
| electrochemical single-molecule afm of the redox metalloenzyme copper nitrite reductase in action. | we studied the electrochemical behavior of the redox metalloenzyme copper nitrite reductase (cnir, achromobacter xylosoxidans) immobilized on a au(111)-electrode surface modified by a self-assembled cysteamine molecular monolayer (sam) using a combination of cyclic voltammetry and electrochemically-controlled atomic force microscopy (in situ afm). the enzyme showed no voltammetric signals in the absence of nitrite substrate, whereas a strong reductive electrocatalytic signal appeared in the pres ... | 2012 | 22696401 |
| the impact of copper, nitrate and carbon status on the emission of nitrous oxide by two species of bacteria with biochemically distinct denitrification pathways. | denitrifying bacteria convert nitrate (no(3) (-) ) to dinitrogen (n(2) ) gas through an anaerobic respiratory process in which the potent greenhouse gas nitrous oxide (n(2) o) is a free intermediate. these bacteria can be grouped into classes that synthesize a nitrite (no(2) (-) ) reductase (nir) that is solely dependent on haem-iron as a cofactor (e.g. paracoccus denitrificans) or a nir that is solely dependent on copper (cu) as a cofactor (e.g. achromobacter xylosoxidans). regardless of which ... | 2012 | 22642644 |
| molecular characterization of imp-type metallo-β-lactamases among multidrug-resistant achromobacter xylosoxidans. | to analyse the metallo-β-lactamase (mbl) genes and their genetic environments in clinical isolates of achromobacter xylosoxidans. | 2012 | 22577105 |
| infective endocarditis caused by achromobacter xylosoxidans: a case report and review of the literature. | an 86-year-old woman who underwent placement of a prosthetic aortic valve for regurgitation 5 years previously was admitted because of spiking fever. the blood culture results were positive for gram-negative rods, which were identified as achromobacter xylosoxidans. approximately 4 months after being sent to the hospital, transthoracic echocardiography revealed vegetation at the prosthetic aortic valve. ultimately, a diagnosis of a. xylosoxidans endocarditis of the prosthetic aortic valve was ma ... | 2012 | 22576403 |
| laser-flash photolysis indicates that internal electron transfer is triggered by proton uptake by alcaligenes xylosoxidans copper-dependent nitrite reductase. | enzyme-catalysed electron transfer reactions are often controlled by protein motions and coupled to chemical change such as proton transfer. we have investigated the nature of this control in the blue copper-dependent nitrite reductase from alcaligenes xylosoxidans (axnir). inter-cu electron transfer from the t1cu site to the t2cu catalytic site in axnir occurs via a proton-coupled electron transfer mechanism. here we have studied the kinetics of both electron and proton transfer independently u ... | 2012 | 22536809 |
| selection and application of endophytic bacterium achromobacter xylosoxidans strain f3b for improving phytoremediation of phenolic pollutants. | while phytoremediation has been considered as an in situ bioprocess to remediate environmental contaminants, the application of functional endophytic bacteria within plants remains a potential strategy that could enhance the plants' efficiency in phytoremediation. in this study, 219 endophytes were isolated from plants that are predominantly located in a constructed wetland, including reed (phragmites australis) and water spinach (ipomoea aquatica). twenty-five strains of the isolated endophytes ... | 2012 | 22497718 |
| a heat-stable cytotoxic factor produced by achromobacter xylosoxidans isolated from brazilian patients with cf is associated with in vitro increased proinflammatory cytokines. | recently, achromobacter xylosoxidans has been related to chronic lung diseases in patients suffering from cystic fibrosis (cf), but its involvement has not been elucidated. some virulence properties of a. xylosoxidans isolated from brazilian patients with cf were revealed in this work. | 2012 | 22440828 |
| characterization of a novel copper-haem c dissimilatory nitrite reductase from ralstonia pickettii. | nirs (nitrite reductases) convert nitrite into no in the denitrification process. rpnir (ralstonia pickettii nir), a new type of dissimilatory cu-containing nir with a c-terminal haem c domain from r. pickettii, has been cloned, overexpressed in escherichia coli and purified to homogeneity. the enzyme has a subunit molecular mass of 50515 da, consistent with sequence data showing homology to the well-studied two-domain cu nirs, but with an attached c-terminal haem c domain. gel filtration and co ... | 2012 | 22414182 |
| successful treatment with doripenem of ventriculitis due to achromobacter xylosoxidans. | | 2014 | 22411874 |
| clinical and microbiological evaluation of eight patients with isolated achromobacter xylosoxidans. | achromobacter xylosoxidans causes infections in patients with underlying disorders. the aim of this study was to evaluate achromobacter xylosoxidans cases. eight patients were included, 5 infections and 3 colonizations. three of them survived and 2 died. the predisposing factor was catheter. infection control measures could prevent infection. | 2012 | 22404460 |
| synthesis, characterization, and antimicrobial activity of silver carbene complexes derived from 4,5,6,7-tetrachlorobenzimidazole against antibiotic resistant bacteria. | silver n-heterocyclic carbene complexes have been shown to have great potential as antimicrobial agents, affecting a wide spectrum of both gram-positive and gram-negative bacteria. a new series of three silver carbene complexes (sccs) based on 4,5,6,7-tetrachlorobenzimidazole has been synthesized, characterized, and tested against a panel of clinical strains of bacteria. the imidazolium salts and their precursors were characterized by elemental analysis, mass spectrometry, (1)h and (13)c nmr spe ... | 2012 | 22402409 |
| in vitro antimicrobial activity of "last-resort" antibiotics against unusual nonfermenting gram-negative bacilli clinical isolates. | in this prospective multicentric study, we assessed the in vitro antimicrobial activity of carbapenems (imipenem, meropenem, and doripenem), tigecycline, and colistin against 166 unusual nonfermenting gram-negative bacilli (nf-gnb) clinical isolates collected from nine french hospitals during a 6-month period (from december 1, 2008, to may 31, 2009). all nf-gnb isolates were included, except those phenotypically identified as pseudomonas aeruginosa or acinetobacter baumannii. minimal inhibitory ... | 2012 | 22335615 |
| achromobacter xylosoxidans keratitis after contact lens usage. | to report on achromobacter xylosoxidans keratitis in two healthy patients who had worn contact lenses foran extended period of time. a 36-year-old female and a 21-year-old female visited our hospital with ocular pain and blurred vision. both patients had a history of wearing soft contact lenses for over fve years with occasional overnight wear. at the initial presentation, a slit lamp examination revealed corneal stromal infiltrations and epithelial defects with peripheral neovascularization in ... | 2012 | 22323886 |
| reductive dechlorination of methoxychlor by bacterial species of environmental origin: evidence for primary biodegradation of methoxychlor in submerged environments. | methoxychlor [1,1,1-trichloro-2,2-bis(4-methoxyphenyl)ethane] is an organochlorine insecticide that undergoes dechlorination in natural submerged environments. we investigated the ability to dechlorinate this compound in seven environmental bacterial species ( aeromonas hydrophila , enterobacter amnigenus , klebsiella terrigena , bacillus subtilis , achromobacter xylosoxidans , acinetobacter calcoaceticus , and mycobacterium obuense ) and the enteric bacterium escherichia coli as a positive cont ... | 2012 | 22292429 |
| calcaneal osteomyelitis due to achromobacter xylosoxidans: a case report. | achromobacter xylosoxidans (a. xylosoxidans) has been described as an opportunistic pathogen causing infection. the case we describe is that of an elderly man who had osteomyelitis of calcaneal bone caused by a. xylosoxidans. as far as we are aware there are only 5 cases of osteomyelitis with a. xylosoxidans in the literature. impaired defensive mechanism of the foot in direct contact with this waterborne bacterium can cause this disease. because of the high level of antibiotic resistance of thi ... | 2012 | 22286410 |
| new treatments for emerging cystic fibrosis pathogens other than pseudomonas. | the development of antimicrobial treatments for respiratory pathogens in cystic fibrosis (cf) has been an integral component to the increased survival of cf patients over the past fifty years. despite significant treatment advances, however, respiratory failure secondary to chronic bacterial pulmonary infection remains the primary cause of death in cf patients. the purpose of this review is to discuss emerging pathogens (other than pseudomonas) in cf by describing the characteristics of the orga ... | 2012 | 22229574 |
| native valve infective endocarditis due to achromobacter xylosoxidans in an apparently immunocompetent individual. | a 79-year-old woman presented with fever, lethargy and weight loss. clinically, the patient was confused, frail and had a systolic murmur. her temperature was 38 °c and she remained persistently febrile. initial investigations revealed neutrophilia with an elevated c reactive protein level. multiple peripheral blood cultures grew achromobacter xylosoxidans, a gram-negative rod, which is a very rare cause of infection in patients who are immunocompetent. subsequent transoesophageal echocardiograp ... | 2010 | 22798095 |
| progress in definition, prevention and treatment of fungal infections in cystic fibrosis. | cystic fibrosis (cf) is a chronic lethal multi-system condition; however, most of the morbidity and mortality is dependent on the status of the respiratory system. progressive respiratory decline is mediated by chronic infection and inflammation, punctuated by important acute events known as pulmonary exacerbations which can lead to accelerated decline. the main bacterial species causing infections include pseudomonas aeruginosa, staphylococcus aureus, haemophilus influenzae and achromobacter xy ... | 2017 | 28762125 |
| air pollution exposure is associated with mrsa acquisition in young u.s. children with cystic fibrosis. | the role of air pollution in increasing susceptibility to respiratory tract infections in the cystic fibrosis (cf) population has not been well described. we recently demonstrated that chronic pm2.5 exposure is associated with an increased risk of initial pseudomonas aeruginosa acquisition in young children with cf. the purpose of this study was to determine whether pm2.5 exposure is a risk factor for acquisition of other respiratory pathogens in young children with cf. | 2017 | 28750627 |
| seasonality of acquisition of respiratory bacterial pathogens in young children with cystic fibrosis. | seasonal variations are often observed for respiratory tract infections; however, limited information is available regarding seasonal patterns of acquisition of common cystic fibrosis (cf)-related respiratory pathogens. we previously reported differential seasonal acquisition of pseudomonas aeruginosa in young children with cf and no such variation for methicillin-susceptible staphylococcus aureus acquisition. the purpose of this study was to describe and compare the seasonal incidence of acquis ... | 2017 | 28599639 |
| differences in gene expression profiles between early and late isolates in monospecies achromobacter biofilm. | bacteria of genus achromobacter are emerging pathogens in cystic fibrosis (cf) capable of biofilm formation and development of antimicrobial resistance. evolutionary adaptions in the transition from primary to chronic infection were assessed by transcriptomic analysis of successive isolates of achromobacter xylosoxidans from a single cf patient. several efflux pump systems targeting antimicrobial agents were upregulated during the course of the disease, whereas all genes related to motility were ... | 2017 | 28534862 |
| septic arthritis of the temporomandibular joint secondary to acute otitis media in an adult: a rare case with achromobacter xylosoxidans. | septic arthritis of the temporomandibular joint (satmj) is a rare complication of acute otitis media (aom) with only four reported cases in the english and japanese literature. based on the unusual nature of this clinical condition, we discuss the first documented case due to achromobacter xylosoxidans and the utility of myringotomy with long-term intravenous antibiotics via a peripherally inserted central catheter (picc). we describe the case of a 76-year-old male patient that was brought in by ... | 2017 | 28458938 |
| hypertonic saline as a useful tool for sputum induction and pathogen detection in cystic fibrosis. | the aim of this study was to compare the qualitative and semi-quantitative detection of pathogens in the airway secretions of patients with cystic fibrosis (cf) and the sputum induction capacity before and after inhalation of 7% hypertonic saline solution (hss). | 2017 | 28455785 |
| engineering proximal vs. distal heme-no coordination via dinitrosyl dynamics: implications for no sensor design. | proximal vs. distal heme-no coordination is a novel strategy for selective gas response in heme-based no-sensors. in the case of alcaligenes xylosoxidans cytochrome c' (axcp), formation of a transient distal 6cno complex is followed by scission of the trans fe-his bond and conversion to a proximal 5cno product via a putative dinitrosyl species. here we show that replacement of the axcp distal leu16 residue with smaller or similar sized residues (ala, val or ile) traps the distal 6cno complex, wh ... | 2017 | 28451315 |
| prevalence and outcomes of achromobacter species infections in adults with cystic fibrosis: a north american cohort study. | achromobacter species are increasingly being detected in cystic fibrosis (cf) patients, with an unclear epidemiology and impact. we studied a cohort of patients attending a canadian adult cf clinic who had positive sputum cultures for achromobacter species in the period from 1984 to 2013. infection was categorized as transient or persistent (≥50% positive cultures for 1 year). those with persistent infection were matched 2:1 with age-, sex-, and time-matched controls without a history of achromo ... | 2017 | 28446570 |