| pancreatic adenocarcinoma in a donkey. | | 1982 | 7173147 |
| glycosylation patterns of the envelope glycoproteins of an equine-virulent venezuelan encephalitis virus and its vaccine derivative. | the equine-virulent venezuelan encephalitis virus, trinidad donkey (trd), was compared to its vaccine derivative, tc-83 virus, by examining the glycosylation of the two structural envelope glycoproteins (e1 and e2). the number of size classes of glycopeptides on the glycoproteins was determined by p-6 column chromatography following pronase digestion. the e1 glycoprotein had three glycopeptide size species and the e2 glycoprotein contained four size species ranging in mol. wt. from 1900 to 2700. ... | 1982 | 7175499 |
| studies on strongylus asini. i. experimental infestation of equines. | infective larvae were harvested from a culture of eggs collected from adult strongylus asini recovered from a free-ranging burchell's zebra, equus burchelli, in the kruger national park. worm-free zebra, horse and donkey foals were successfully infested, but infestation failed in a mule foal. at slaughter, 117-125 days post-infestation, s. asini in their 4th moult were recovered from the liver and portal veins. this is the first report of successful experimental infestation of these hosts with s ... | 1982 | 7177594 |
| field use of an acetylpromazine/methadone/ketamine combination for anaesthesia in the horse and donkey. | | 1982 | 7179678 |
| administration of antisomatotropin serum in diabetes mellitus. | the effect of antisomatotropin serum (ass), raised in horse against human growth hormone, on the carbohydrate metabolism of diabetics has been investigated. among the eight diabetic patients treated so far two had gh secreting pituitary adenoma, two insulin-dependent, and four others adult onset diabetes mellitus. the glucose tolerance curve improved in all but one patient. the effect lasted for two--four weeks. because of this short time of efficiency, the place of ass in the definite treatmen ... | 1981 | 7227326 |
| immunochemical determination of ldh-1. | an evaluation of a new immunochemical method for the heart isoenzyme of lactic dehydrogenase (ldh-1) is described. in this assay, a goat antibody against the m subunit of ldh is added to a patient's serum. donkey antigoat gamma globulin is then added, which precipitates the m-anti-m complex. ldh activity in the supernatant is thus a measure of the heart isoenzyme, since this isoenzyme is not precipitable by the anti-m antibody. assays for total ck, ck-mb, and total ldh, and ldh electrophoresis w ... | 1981 | 7234756 |
| anthelmintic efficiency of fenbendazole in equines. | a single oral dose of fenbendazole (fbz) at 10mg/kg body mass was given to 5 donkeys. a further 5 donkeys were dosed with a medicated lick (1 mg fbz/g lick) until the oral consumption was 10mg/kg body mass. in both trials fbz was highly effective against adults of the following genera: cyathostomum, cylicocyelus, cylicostephanus, cylicodontophorus, poteriostomum, cabellonema, craterostomum and triodontophorus; similarly high efficiency was obtained against the following species: habronema majus, ... | 1980 | 7241490 |
| sickled erythrocytes accelerate clotting in vitro: an effect of abnormal membrane lipid asymmetry. | a membrane lipid abnormality induced by sickling and found as a permanent alteration in the irreversibly sickled cell (isc) is the rearrangement of phosphatidyl ethanolamine (pe) and phosphatidyl serine (ps) from the inner to the exterior side of the lipid bilayer. since ps can provide a catalytic surface for the binding of blood coagulation factors and thus can exhibit procoagulant activity, we investigated the influence of oxy and deoxy reversibly sickled cells (rsc) ass well as isc on clottin ... | 1981 | 7248527 |
| dietary and hormonal regulation of urea cycle enzymes in rat liver. | when 6-week-old rats fed normal diet (22% protein) were transferred to 10 and 75% protein diet, the levels of urea cycle enzymes showed decreases and increases respectively. the activities expressed as units per gram wet weight of liver had not stabilized after 7 days on the new diet; the corresponding specific activities were closer to leveling off. four daily injections of cortisol raised cps, ass, and arginase. the percentage increases were greater on a 10 than on a 75% protein diet. adrenale ... | 1981 | 7250092 |
| [acetylsalicylic acid and food additive intolerance in urticaria, bronchial asthma and rhinopathy]. | adverse reactions (urticaria, angio-edema, bronchoconstriction, purpura) to aspirin (ass) and food-and-drug additives such as the yellow dye tartrazine and the preservative benzoate are observed all over the world. since the exact pathogenetic mechanisms of this condition is unknown, it is described as intolerance or pseudo-allergy and has been related to an imbalance of prostaglandin synthesis. among 620 patients with urticaria, bronchial asthma or chronic rhinitis, oral provocation tests with ... | 1981 | 7291963 |
| a survey of schoolchildren from a severe endemic goitre area in spain. | all the boys and girls between six and fourteen years old regularly attending school in three villages from an area in spain known ass las hurdes were studied with respect to thyroid size, body weight and height. casual urine samples were obtained for the determination of iodine and creatine concentrations. capillary blood was spotted on filter paper and used for the determination of thyroxine and thyrotropin by radioimmunoassay. the same survey was carried out in 354 school children from madrid ... | 1981 | 7302120 |
| vestibulo-thalamic projection to the anterior suprasylvian cortex of the cat. | suggestive evidence as to the site of a major thalamic relay of the vestibular projection to the anterior suprasylvian (ass) cortex in the cat has been obtained using the retrograde axonal transport of horseradish peroxidase. the thalamo-cortical neurons are located in several patches surrounding the posterior margins of the ventro-basal complex (vb). this area also was found to receive vestibulo-thalamic projections. it comprises different nuclear groups known to carry somatic, acoustic, visual ... | 1981 | 7308362 |
| steatitis in two donkey foals. | | 1981 | 7316897 |
| brain-stem responses when masking with wide-band and high-pass filtered noise. | investigations, using click stimuli masked by wide-band and high-pass filtered noise with cut-off frequencies of 2 600, 1 250 and 850 hz were carried out. the latency shift of a response evoked by a click of 60 db hl and wide-band masking at 80 db hl is 0.2 - 0.3 ms for wave i and about 0.6 ms for wave v. the results obtained with high-pass masking at various cut-off frequencies differ distinctly from those found by other authors. for instance, when using high-pass masking noise of a lower limit ... | 1981 | 7323676 |
| trichophyton mentagrophytes infection in the domestic donkey (equus asinus asinus). | | 1981 | 7325738 |
| [the genus onchocherca : hypothesis on its evolution and a key to the species (author's transl)]. | a phylogenetic tree and a dichotomic key to the species in the genus onchocerca are proposed. the origin and principal evolution have taken place in africa where the most primitive species (o. railieti in the donkey) and the greatest number of species (half of the 24 representatives of the genus) occur. this evolution apparently took place in a relatively recent geological period, corresponding perhaps to the establishment of the equidae in africa during the pleistocene. the species in humans, o ... | 1981 | 7332196 |
| experimental transmission of echinococcus granulosus of "camel-dog" origin to goats, sheep, cattle and donkeys. | the infectivity of a camel strain of echinococcus granulosus experimentally raised in dogs for domesticated food and burden animals was investigated. of the animal species that were inoculated orally with gravid segments, hydatid cysts developed poorly in goats and sheep, less well in cattle and not at all in donkeys by six month post-inoculation. cysts were most frequently found in the lungs, although other organs such as liver and spleen also contained cysts. histological examination of affect ... | 1981 | 7333783 |
| rabies in farm livestock in nigeria. | between 1944 and 1977, the distribution of confirmed cases of rabies in farm livestock in nigeria were 15 in cattle, 8 in goats, 4 each in sheep, pigs and horses and two in donkeys respectively. the less-cared-for pastoralist sheep - dogs as well as stray dogs have so far been the sole propagating animal species of rabies to farm livestock although wild fauna have been suspected. the fact that cases are sporadic and lower incidence of livestock rabies is generally reported than the number that a ... | 1981 | 7333785 |
| genetic linkage between the ah locus and a major gene that inhibits susceptibility to audiogenic seizures in mice. | mice of the dba/2 (d2) strain are highly susceptible to sound-induced seizures at 21 days of age; whereas, mice of the c57bl/6 (b6) strain are resistant to these seizures. although the difference in susceptibility to audiogenic seizures (ass) between these two strains is inherited as a multiple-factor trait, an association was observed between susceptibility to ass and the ah locus. the ah locus controls the inducibility of aryl hydrocarbon hydroxylase (ahh) activity by a number of aromatic hydr ... | 1981 | 7341353 |
| remanent magnetic fields for measuring particle retention and distribution in the lungs. | a relatively inexpensive method for the noninvasive in vivo detection of ferrimagnetic particles within the lungs of a large laboratory animal, viz., the donkey, is described. the particles were neutron activated prior to inhalation, which permitted a comparison of two different retention measurements for the same particles, i.e., a well-characterized radiological-detection method concurrent with the newer magnetic-field technique. the long-term clearance of the particles from the lung was monit ... | 1981 | 7346267 |
| ganglioside pattern and sialic acid content of horse, donkey, and mule brain. | | 1980 | 7354347 |
| a short study of the seminal colliculus in some mammals. | the seminal colliculus is completely absent in the donkey. it is fibroglandular in the males of camel, ox, buffalo and pig. prostatic acini are richly found in its depth. they are lined by cubical or low columnar epithelium, are separated from each other by trabeculae of connective tissue and smooth muscle, and separated from the deeper prostrate gland by the striated muscle of the urethra. a rare type of seminal colliculus was once encountered in the ox. this type is muscular with autonomic gan ... | 1980 | 7386162 |
| genetic analysis of audiogenic seizure susceptibility in c57bl/6j x dba/2j recombinant inbred strains of mice. | the inheritance of susceptibility to audiogenic seizures (ass) was studied in the c57bl/6j (b6) and dba/2j (d2) progenitor strains, their reciprocal f(1) hybrids, backcross generations and in 21 b6 x d2 recombinant inbred (ri) strains of mice at 21 days of age. all of the d2 mice tested experienced ass, whereas none of the b6 mice responded to the sound. although 23% of the f(1) mice experienced wild running, they were generally as resistant to ass as their b6 parents. mice of the f(1)x b6 backc ... | 1980 | 7399258 |
| hunger vs thirst in the burro (equus asinus). | | 1980 | 7403300 |
| a novel synergistic effect of alanosine and guanine on adenine nucleotide synthesis in mammalian cells. alanosine as a useful probe for investigating purine nucleotide metabolism. | a novel synergistic effect of the antitumor agent alanosine (2-amino-3-(hydroxynitrosoamino) propionic acid), which specifically inhibits the enzyme adenylosuccinate synthetase (ass) and guanine on the growth of chinese hamster ovary (cho) cells and human diploid fibroblasts (hdf) has been observed. in the presence of subinhibitory concentrations of alanosine, both cho cells and the hdf show excessive sensitivity to exogenous guanine--a phenotype which closely resembles that seen with some of th ... | 1980 | 7410492 |
| purification and characterization of donkey chorionic gonadotrophin. | serum of the pregnant donkey, like that of the mare, contains a gonadotrophin of chorionic origin. the chorionic gonaditrophin of the donkey (dcg) has been isolated in purified form from the serum of pregnant donkeys using methodology previously employed for the purification of pregnant mare chorionic gonadotrophin (ecg). unlike ecg, dcg is predominatly an lh in biological tests. in the in-vitro rat leydig cell assay, dcg was as active as ecg, but in the in-vitro rat seminiferous tubule assay fo ... | 1980 | 7411010 |
| variation of acidic prealbumins in the donkey (equus asinus). | starch gel electrophoresis of 55 donkey serum samples revealed three prealbumin (pr) phenotypes temporarily designated pr m, pr mt and pr t. the distribution was in agreement with a genetic theory of two codominant alleles of frequencies, prm = 0.87 and prt - 0.13. variation was also observed for proteins migrating with the same rate as the xh zones in the horse. | 1980 | 7436051 |
| pneumonia in a donkey. | | 1980 | 7445355 |
| gastrointestinal osmolality electrolyte and organic acid composition in five species of east african herbivorous mammals. | inherent differences observed in ionic composition of gastrointestinal contents due to diet, feeding regimen and (or) site along the length of the digestive tract were controlled so that a clearer understanding of species differences could be obtained. three species of ruminants (i.e., zebu cattle, sheep and goat), a pseudo-ruminant (camel) and a nonruminant (donkey) were compared. specific differences were observed in organic acid concentration, ph and electrolyte composition at various sites a ... | 1980 | 7462117 |
| hydatidosis in donkeys in morocco. | | 1980 | 7469567 |
| [jackson's sarcoid: the 1st description of a case observed in tunisia]. | the first description of sarcoid of jackson observed in tunisia in an adult donkey permit to the authors to give a light to the possibilities of its experimental transmission. | 1980 | 7469616 |
| the nucleotide sequence of asinine herpesvirus 3 glycoprotein g indicates that the donkey virus is closely related to equine herpesvirus 1. | the nucleotide sequence of the glycoprotein g (gg) homologue of asinine herpesvirus 3 (ahv3), a respiratory alphaherpesvirus of donkeys, was determined. the ahv3 gg gene consists of 1233 base pairs (bp) and codes for a predicted protein of 411 amino acids. this is identical in size to the equine herpesvirus 1 (ehv1) gg gene and 6 amino acids longer than the equine herpesvirus 4 (ehv4) gg gene. the predicted amino acid sequence of ahv3 gg has characteristics of a class 1 membrane protein. the ami ... | 1995 | 7487497 |
| localization of four antigenic sites involved in venezuelan equine encephalomyelitis virus protection. | stable neutralization and protection escape variants of a virulent strain (trinidad donkey) of the vee virus were selected by monoclonal antibodies (mabs). determination of nucleotide sequences of nine variants revealed a clustering of single mutations in four regions of the e1 and e2 glycoproteins. involvement of amino acid residues 206 (site e1-1), 57 and 59 (site e2-2), 180, 182, 213, 214 and 216 (site e2-6) and 232 (site e2-3) in protective epitopes was demonstrated. | 1994 | 7529989 |
| diffuse large cell lymphomas exhibit frequent deletions in 9p21-22 and 9q31-34 regions. | we have previously identified deletions of 9p and 9q in a cytogenetic analysis of a large series of non-hodgkin's lymphomas (nhls), which suggested loss of candidate tumor suppressor genes (tsgs). in order to define these deletions at the molecular level, we performed an loh analysis of a panel of paired normal and tumor dnas comprising 13 cases of diffuse lymphoma with a large cell component (dllc) and 18 cases of burkitt's lymphoma (bl). the loci tested comprised eight polymorphic probes mappe ... | 1995 | 7534108 |
| localization of a protective epitope on a venezuelan equine encephalomyelitis (vee) virus peptide that protects mice from both epizootic and enzootic vee virus challenge and is immunogenic in horses. | in order to define more precisely the protective epitope encoded within the first 25 amino acids (aa) of the e2 glycoprotein of the trinidad donkey strain of venezuelan equine encephalomyelitis (vee) virus, we examined the immunogenicity of smaller peptides within the first 19 aa. pep1-9 and pep3-10 elicited virus-reactive antibody, but failed to protect mice from virus challenge. additionally, pep3-10 was identified by a competitive binding assay using overlapping peptide octamers as the putati ... | 1995 | 7543231 |
| caloric intake stimulates growth hormone secretion in food-deprived rats with anterolateral deafferentation of the medial basal hypothalamus or administered antiserum to somatostatin. | in rats, food deprivation inhibits episodic growth hormone (gh) secretion. on the basis of previous studies, we hypothesized that during a recovery from prolonged fasting, caloric intake stimulates the release of gh-releasing factor (grf) and this process does not depend on the specific macronutrients in the meal, while protein in the meal acts to restore characteristic ultradian rhythmicity of gh secretion. to test this hypothesis, the effect of caloric intake on gh secretion was examined in fa ... | 1995 | 7550296 |
| disposition of penicillin g sodium following intravenous and oral administration to equidae. | the present study was designed to determine and compare the plasma disposition and pharmacokinetics of penicillin g sodium following intravenous (i.v.) administration to horses, ponies and donkeys. the plasma disposition and pharmacokinetics of penicillin g was similar in horses, ponies and donkeys (elimination half-lives--39.0, 27.3 and 31.5 min, respectively) and a dosage interval of 6-8 h would be suitable to treat infections caused by susceptible bacteria. although penicillin g was absorbed ... | 1995 | 7552196 |
| pancreatic secretory trypsin inhibitor gene is highly expressed in the liver of adult-onset type ii citrullinemia. | deficiency of argininosuccinate synthetase (ass) causes citrullinemia. type ii citrullinemia is found in most patients with adult-onset citrullinemia in japan, and ass is deficient specifically in the liver. previous studies have shown that the decrease of hepatic ass activity is caused by a decrease in enzyme protein with normal kinetic properties and that there are no apparent abnormalities in the amount, translational activity, and nucleotide sequence of hepatic ass mrna. recent results of ho ... | 1995 | 7556646 |
| nature and frequency of mutations in the argininosuccinate synthetase gene that cause classical citrullinemia. | citrullinemia is an autosomal recessive disorder caused by a genetic deficiency of argininosuccinate synthetase (ass). so far 20 mutations in ass mrna have been identified in human classical citrullinemia, including 14 single base changes causing missense mutations in the coding sequence of the enzyme, 4 mutations associated with an absence of exons 5, 6, 7, or 13 in mrna, 1 mutation with a deletion of the first 7 bases in exon 16 (which is caused by abnormal splicing), and 1 mutation with an in ... | 1995 | 7557970 |
| continuing prevalence of african horse sickness in nigeria. | equine sera collected from 10 widely separated regions throughout nigeria were tested for antibodies against african horse sickness viruses (ahsv) using a competitive enzyme-linked immunosorbent assay (elisa). the animals sampled included imported, exotic horses, indigenous and locally cross-bred (local) horses and african donkeys. a high percentage of the sera (79.8%) were positive, confirming the continued prevalence of ahsv antibodies in nigerian horses and donkeys. | 1995 | 7569227 |
| donkey klossiellosis in kenya. | out of eight donkeys examined, two had gametogonic and sporogonic stages of klossiella equi in their kidneys. gametogonic stages included microgametocytes and macrogametocytes, some of them in syzygy. they were found in enlarged parasitophorous vacuoles situated in epithelial cells of the renal tubules. sporonts were seen in the epithelial cells protruding into the tubular lumen while sporoblasts, sporocysts and sporozoites were found freely in the tubular lumen. entire sporocysts were rarely en ... | 1995 | 7571332 |
| assumed oxygen consumption based on calculation from dye dilution cardiac output: an improved formula. | this study was performed because of observed differences between dye dilution cardiac output and the fick cardiac output, calculated from estimated oxygen consumption according to lafarge and miettinen, and to find a better formula for assumed oxygen consumption. in 250 patients who underwent left and right heart catheterization, the oxygen consumption vo2 (ml.min-1) was calculated using fick's principle. either pulmonary or systemic flow, as measured by dye dilution, was used in combination wit ... | 1995 | 7588904 |
| proteolytic cleavage of vp2, an outer capsid protein of african horse sickness virus, by species-specific serum proteases enhances infectivity in culicoides. | purified african horse sickness virus (ahsv) was fed, as part of a blood meal, to adult females from a susceptible colony of culicoides variipennis, established in the insectories at the institute for animal health, pirbright laboratory, uk. the meal consisted of heparinized blood obtained from ovine, bovine, equine (horse and donkey) or canine sources spiked with ahsv serotype 9 (ahsv9). the infectivity levels observed for c. variipennis varied significantly, according to the source of the bloo ... | 1995 | 7595366 |
| an investigation into the potential veterinary needs of a semi-rural low-income community. | the diagnostic phase of an interactive veterinary research evaluation model was used in the investigation into the potential veterinary needs of a low-income, semi-rural community. the economic status of households was estimated according to an economic situation score (esscore) and a subjective nutritional score (sns). data were gathered by means of structured interviews and direct observations. sixty-one per cent of the households (n = 190) owned animals. dogs were the animal most frequently o ... | 1994 | 7595924 |
| animal traction in south africa: research priorities in veterinary science. | during june 1994, members of numerous organisations with a vested interest in animal traction in south africa met for a one-day workshop, the initial activity of a forum on working animals. the workshop was sponsored by the foundation for research development in south africa. the individuals who attended were representatives of academic and government institutions, farmer and civic organisations, and included veterinarians and veterinary scientists, administrators, traction experts from the regi ... | 1994 | 7602567 |
| wesselsbron virus antibody in domestic animals in nigeria: retrospective and prospective studies. | retrospective and prospective serological surveys to determine the prevalence of wesslsbron (wsl) virus infections in animal populations were carried out in different vegetational zones in nigeria. sera from 1,492 animals comprising 292 camels, 81 horses, 4 donkeys, 320 cattle, 235 sheep, 260 goats, 114 pigs, 101 dogs and 85 domestic fowls were assayed by haemagglutination-inhibition (hi) test for presence of antibodies to wsl virus and other flavivirus antigens: yellow fever (yf), potiskum (pot ... | 1995 | 7603342 |
| [saccharomyces cerevisiae ade12 gene, coding for adenylosuccinate synthetase (ec 6.3.4.4). cloning, sequencing, expression, and superproduction]. | the cloning and sequencing of saccharomyces cerevisiae ade12 gene encoding the structure of adenylsuccinate synthetase (ass) are reported for the first time. comparative analysis of all known ass sequences was carried out. regulation of ade12 gene expression by exogenic adenine was carried out. the properties of ass which was isolated and purified from overproducing yeast strain were examined. | 1995 | 7603488 |
| bloodfeeding behavior of anopheles sacharovi in turkey. | the feeding habits of anopheles sacharovi under natural conditions and in feeding rooms were investigated by use of the gel diffusion technique. mosquitoes were collected from various villages of cukurova and also from feeding rooms especially prepared for these experiments. human, cow, sheep, chicken, horse, and donkey were used as hosts in these rooms. the results showed that an. sacharovi is a zoophilic species. the females preferred donkey when human, cow, sheep, chicken, and horse were equa ... | 1995 | 7616176 |
| [prevention of reinfarction with 100 mg or 30 mg ass daily?]. | the prevention of heart infarction with 100 mg aspirin is common practice in germany, in spite of the fact that it is based on only two small studies, the results of which are not generalized. over 14 years, several experimental and clinical studies have shown that 20-30 mg aspirin/d for pharmacokinetic reason selectively inhibit the thromboxane synthesis while the endogenous prostacyclin synthesis remains intact. prostacyclin plays an important cardioprotective role for the ischemic heart, havi ... | 1995 | 7625094 |
| seroepidemiological and molecular evidence for the presence of two h3n8 equine influenza viruses in china in 1993-94. | in may 1993, a severe epidemic of respiratory disease began in horses in inner mongolia and spread throughout horses in china. the disease affected mules and donkeys as well as horses but did not spread to other species, including humans. the severity of the disease raised the question of whether the outbreak might have been caused by the new avian-like influenza viruses detected in horses in china in 1989 or by current variants ofa/equine/miami/1/63 (h3n8) (equine-2) or by a reassortant between ... | 1995 | 7636481 |
| cloning and analysis of the cdna encoding the horse and donkey luteinizing hormone beta-subunits. | the coding regions of the horse (equus caballus) and donkey (e. asinus) luteinizing hormone (lh) beta-subunit transcripts were cloned from pituitary gland rna, in order to investigate their relationships to the corresponding equine chorionic gonadotropin (cg) beta-subunits and to further understand the unusual receptor-binding properties of equine lh and cg. the horse and donkey lh beta-subunit sequences were very similar (97% identity at the nucleotide (nt) level; 93% at the amino acid (aa) lev ... | 1995 | 7642105 |
| antegrade scrotal sclerotherapy for the treatment of varicocele in childhood and adolescence. | to test the efficacy of antegrade scrotal sclerotherapy (ass) for the treatment of varicocele in teenagers. | 1995 | 7648061 |
| hyperlipidemia, hyperlipemia, and hepatic lipidosis in american miniature horses: 23 cases (1990-1994). | the medical records of 23 american miniature horses with hyperlipidemia, hyperlipemia, or hepatic lipidosis were reviewed. the most common clinical signs were anorexia and lethargy. the mean duration of clinical signs was 2.4 days. a primary disease was identified in 19 cases. enterocolitis was the most common primary disease (n = 10). intentional feed restriction, as part of treatment for colic, resulted in hyperlipemia in 2 horses and hyperlipidemia in 1. four horses had primary hyperlipemia, ... | 1995 | 7649775 |
| [thrombocyte function of healthy probands taking 50 mg of acetylsalicylic acid per day]. | the antithrombotic effect of acetylsalicylic acid (ass) is attributed in part to its inhibitory action on platelet cyclooxygenase and, thereby, thromboxane a2 (txa2) formation. the therapeutic goal of low-dose ass regimens was the development of a preparation showing a high inhibitory capacity on platelet txa2 generation whilst leaving vascular prostaglandin i2 (pgi2) synthesis unaffected, thereby minimizing side effects. the effect of a new acid-resistant preparation of 50 mg ass (thrombo-ass 5 ... | 1995 | 7676685 |
| attenuation of venezuelan equine encephalitis virus strain tc-83 is encoded by the 5'-noncoding region and the e2 envelope glycoprotein. | the virulent trinidad donkey (trd) strain of venezuelan equine encephalitis (vee) virus and its live attenuated vaccine derivative, tc-83 virus, have different neurovirulence characteristics. a full-length cdna clone of the tc-83 virus genome was constructed behind the bacteriophage t7 promoter in the polylinker of plasmid puc18. to identify the genomic determinants of tc-83 virus attenuation, trd virus-specific sequences were inserted into the tc-83 virus clone by in vitro mutagenesis or recomb ... | 1993 | 7679745 |
| neuronal responses to vestibular and callosal stimulation in the anterior suprasylvian gyrus of the cat. | neuronal responses to electrical stimulation at the horizontal ampulla (ha), vestibular nerve (at the windows) and corpus callosum (cc) were investigated in neurons in the anterior suprasylvian gyrus of the cat. the field potentials to ha stimulation had short latency: 2.9 +/- 0.3 (mean +/- sd) ms from the stimulus to the onset and 5.6 +/- 1.9 ms to the peak. the focus of the evoked potentials was located in the anterior suprasylvian (ass) gyrus or near the ass sulcus. ha stimulation activated 6 ... | 1993 | 7683394 |
| [serum argininosuccinate synthetase (ass) in patients with chronic hepatitis c treated with interferon]. | serum ass and serum gpt levels were determined in 16 patients with chronic hepatitis c treated with interferon. in all the patients, the serum ass level decreased earlier than the serum gpt level, and this tendency was remarkable in patients who excellently responded to the treatment. furthermore, the serum ass level was fluctuated when the serum gpt levels being continuously flat in the course of the treatment, probably because of the shorter half life of ass in the serum. in conclusion, the se ... | 1993 | 7685731 |
| kinetics of interaction of hiv reverse transcriptase with primer/template. | intrinsic protein fluorescence of reverse transcriptases from hiv-1 and hiv-2 provides a sensitive signal for monitoring the interaction of the enzymes with primer/template duplex molecules. kd values for 18/36-mer dna/dna duplexes were found to be in the range of a few nanomolar (about 3 times higher for the enzyme from hiv-2 than for that from hiv-1). the quenching of protein fluorescence induced on binding primer/template, together with an increase in extrinsic fluorescence on interaction wit ... | 1993 | 7688571 |
| [anesthetic management for a patient with citrullinemia and liver cirrhosis]. | we successfully anesthetized a 53-year-old female with hypercitrullinemia and severe liver cirrhosis. the hypercitrullinemia was accompanied with chronic hepatic encephalopathy due to hyperammonemia, which resulted from decreased activity of one of the urea cycle enzymes, argininosuccinate synthetase (ass). she was scheduled for replacement arthroplasty of a fractured femoral neck. she suffered a consciousness disturbance due to hyperammonemia, which was successfully treated by oral administrati ... | 1995 | 7699832 |
| features of the dna fingerprinting probe pitz1. | stringently controlled plasmids generate dna fingerprint patterns in mammals when used at low hybridization temperatures. in order to develop a probe for use in paternity testing in cattle we screened a bovine, partial genomic plasmid library with the pcr-amplified ori region of plasmid p1. of eight isolated clones one generated strong band patterns at high stringency in various mammalian species (data not shown). sequence analysis revealed an imperfect, compound dinucleotide repeat region, whic ... | 1995 | 7702209 |
| attenuation of acute inflammatory effects of silica in rat lung by 21-aminosteroid, u74389g. | chemical alteration of the glucocorticoid, methylprednisolone, has led to the introduction of a new class of compounds called the 21-aminosteroids (21-ass). the purpose of this study was to investigate the effect of the 21-as, u74389g, on silica-induced acute lung injury. male fischer 344 rats were treated intraperitoneally with saline or u74389g in a total dose of 15 mg/kg divided into three injections of 5 mg/kg separated by 4 h. following the first treatment, animals from the two groups were ... | 1995 | 7705890 |
| nematocera (ceratopogonidae, psychodidae, simuliidae and culicidae) and control methods. | the biology, veterinary importance and control of certain nematocera are described and discussed. culicoides spp. (family ceratopogonidae) transmit the arboviruses of bluetongue (bt), african horse sickness (ahs), bovine ephemeral fever (bef) and akabane. some other arboviruses have been isolated from these species, while fowl pox has been transmitted experimentally by culicoides. these insects are vectors of the parasitic protozoans leucocytozoon caulleryi and haemoproteus nettionis, and the pa ... | 1994 | 7711309 |
| practical questions about therapy of hypertension with ace inhibitors. j. scholze, berlin, on the 24-hour effect, possible combinations and side-effects of ace inhibitors--ass/antirheumatic agents. | | 1995 | 7713469 |
| [effects of the leaves of acanthopanax senticosus (rupr. et maxim.) harms. on myocardial infarct size in acute ischemic dogs]. | effects of saponin isolated from the leaves of acanthopanax senticosus (ass) on myocardial infarct size were studied in acute ischemic dogs. the results showed that ass (in a dosage of 25.50 mg/kg, iv) could significantly reduce the sizes of acute myocardial infarcts and decline the serum ck and ldh activity at 6h after ligation of lad. it could also decrease the serum ffa levels at 3h and 6h after lad occlusion. | 1994 | 7718140 |
| 6 alpha-biotinylated estrone: novel tracer in competitive chemiluminescence immunoassay of estrone in serum. | we describe the development and validation of a labeled-hapten competitive immunoassay for determining total estrone in serum. for the hapten tracer we use the 6 alpha-biotinylated estrone derivative, 3-hydroxyestra-1,3,5(10)-trien-17-one 6 alpha-n-(epsilon-biotinyl)aminocaproamide (bio-e1). a specific polyclonal rabbit anti-estrone antibody is indirectly bound via an immobilized donkey anti-rabbit antibody on microtiter plate wells. the amount of bio-e1 bound is then measured with streptavidin- ... | 1995 | 7720247 |
| equine parafilariosis in iran. | from march to september 1991, horses (n = 1567), donkeys (n = 112) and mules (n = 96) were examined for equine parafilariosis by random sampling from different areas of iran. the clinical signs of equine parafilariosis were observed in 136 cases of two northern areas (1.4% and 41.3% infection rate) and one northeastern area (6.3% infection rate). most of the infected cases were confirmed by laboratory findings. all infected cases were followed up to establish the epidemiological features. the re ... | 1995 | 7732643 |
| optimization and validation of an elisa to measure specific guinea pig igg1 antibody as an alternative to the in vivo passive cutaneous anaphylaxis assay. | assessment of the allergenic potency of enzymes involves the use of a guinea pig model in which specific igg1 antibody titers are used as the endpoint. the in vivo passive cutaneous anaphylaxis (pca) assay is used to measure specific igg1 antibody. this report describes the development and validation of an enzyme-linked immunosorbent assay (elisa) to measure guinea pig specific igg1 antibody as an in vitro alternative to the pca assay. cross reactivity of various rabbit and mouse (monoclonal) an ... | 1995 | 7737435 |
| neonatal isoerythrolysis in mule foals. | four mule foals received anti-rbc antibody from their dam's colostrum. two foals developed anemia, 1 developed severe thrombocytopenia, and 1 did not develop any clinical or laboratory abnormalities. all foals had the same donkey sire. seven mares, including the dams of foals 1 to 4, bred to the donkey sire produced anti-rbc antibody. two mares produced anti-rbc antibody to the donkey rbc on the first mating. the donkey sire and 18 of its offspring were found to have an rbc antigen unique to mul ... | 1995 | 7744666 |
| clinical, virological and serological responses of donkeys to intranasal inoculation with the ky-84 strain of equine arteritis virus. | the clinical, virological and serological responses of seven female donkeys (equus asinus) to inoculation with the ky-84 strain of equine arteritis virus (eav), a strain that causes moderate to severe clinical signs in horses, was investigated. in the donkeys, the only clinical signs observed were fever (mainly 3-9 days after inoculation), mild depression in four animals, and a slight nasal or ocular discharge in three. all of the donkeys became infected with eav as shown by recovery of the viru ... | 1995 | 7769149 |
| equine viral arteritis in donkeys in south africa. | | 1994 | 7776331 |
| serological relationship between a donkey alphaherpesvirus (isolate m7/91) and equid herpesvirus type 1 and 4. | rabbit hyperimmune serum prepared against a donkey alphaherpesvirus isolate (m7/91), and against ehv-1 and ehv-4 was used to characterise the antigenic relationship between these 3 viruses. serum from immunised rabbits was always more specific for homologous virus and showed different cross reactivity for heterologous virus. it was concluded that the immunologic relationship between the m7/91 isolate and ehv-1, was closer than that between this isolate and ehv-4. a serological survey of donkeys ... | 1994 | 7776336 |
| second locus for hirschsprung disease/waardenburg syndrome in a large mennonite kindred. | we have studied a large mennonite kindred in which 20 members were affected with hirschsprung disease (hscr), 5 of whom had one or more manifestations of waardenburg syndrome (ws) type ii (ws2). eleven additional relatives had signs of ws2 without hscr. since hscr and ws2 each represent perturbations of neural crest migration/differentiation, this large pedigree with apparent cosegregation of hscr and ws2 offered an opportunity to search for linkage between these loci, candidate genes, and rando ... | 1994 | 7802041 |
| [degradation of the constituents in solubilization process of donkey skin]. | dry donkey skin, defatted in advance with hair scraped off, was separately solubilized by heating in sealed tubes at 130 degrees c for 2, 4, 6, 8h. the resultants were clarified and dried as ejiao, whose yield appeared to reach maximum after 4h heating. absorptivities of all four ejiao preparations were in good approximation to standard gelatin. however, their intrinsic viscosity declined in order of prolonged solubilization process, indicating that depolymerization of donkey skin gelatin had ta ... | 1994 | 7811366 |
| alterations in glomerular anionic sites in canine anti-glomerular basement membrane nephritis with onset of severe proteinuria. | rabbit anti-glomerular basement membrane serum (agbm) or normal rabbit serum (nrs) were given intravenously (2 ml/kg body weight) to 8 male beagle dogs. light and transmission electron microscopy and immunofluorescence were performed on the kidneys on day 7 postinjection. alterations of anionic sites (ass) of glomerular basement membrane (gbm) in peripheral, proximal, and paramesangial portions were studied quantitatively by electron microscopy using polyethyleneimine (pei; molecular weight = 1, ... | 1994 | 7817121 |
| linkage analysis of the nail-patella syndrome. | nail-patella syndrome (nps) is an autosomal dominant disorder characterized by dysplasia of nails and patella, decreased mobility of the elbow, iliac horns, and, in some cases, nephropathy. the disorder has been mapped to the long arm of chromosome 9, but the precise localization and identity of the nps gene are unknown. linkage analysis in three nps families, using highly informative dinucleotide repeat polymorphisms on 9q33-q34, confirmed linkage of nps to this chromosome. recombinations were ... | 1995 | 7825584 |
| effect of increasing work rate on metabolic responses of the donkey (equus asinus). | oxygen consumption (vo2) and concentration of venous blood metabolites were measured in donkeys trained to run and to pull loads on a treadmill. vo2 in two donkeys running at maximal speed on a 9.8% slope was 110 +/- 2 ml.min-1.kg-1, approximately 22 times preexercise vo2. average heart rate at maximal vo2 (vo2max) was 223 +/- 2 beats/min, five times the preexercise heart rate. blood lactate increased 14-fold, and blood glucose did not change (p > 0.05). animals running up a 4% incline and incre ... | 1994 | 7836149 |
| hyperlipemia in 9 miniature horses and miniature donkeys. | the medical records from 9 consecutive miniature horses (n = 5) and miniature donkeys (n = 4) with hyperlipemia (serum triglyceride concentration > 500 mg/dl) were reviewed. in all cases, hyperlipemia was a secondary complication of a primary systemic disease including septicemia, colitis, parasitism, esophageal obstruction, gastric impaction and rupture, fecalith, and pituitary adenoma. therapy consisted of specific treatment for the primary disease, supportive care, and nutritional support. th ... | 1994 | 7837116 |
| village health survey of sina mala, gongola state, nigeria. | a survey of the environment, life-style, and health status, knowledge, attitudes and practices in the village of sina mala was carried out prior to the introduction of a village health post by a church-run rural health programme. in addition to the perceived needs of the villagers for a school, easier access to medicine and external assistance with well drilling, the study identified the need to train traditional midwives in hygienic delivery, to make local health workers more aware of onchocerc ... | 1993 | 7839910 |
| frequency and morpho-structural organization of the thyroid gland isthmus in horses, donkeys and small ruminants. | | 1994 | 7840946 |
| hosts of lutzomyia shannoni (diptera: psychodidae) in relation to vesicular stomatitis virus on ossabaw island, georgia, u.s.a. | hosts of lutzomyia shannoni dyar, a suspected biological vector of the new jersey serotype of vesicular stomatitis (vsnj) virus, were determined using an indirect enzyme-linked immunosorbent assay (elisa) of 333 blood-fed female sandflies collected from their diurnal resting shelters on ossabaw island, georgia, u.s.a. sandflies had fed primarily on white-tailed deer (odocoileus virginianus) (81%) and to a lesser extent on feral swine (sus scrofa) (16%), two species of host infected annually with ... | 1994 | 7841487 |
| postmitotic oligodendrocytes generated during postnatal cerebral development are derived from proliferation of immature oligodendrocytes. | the phenotype of proliferating glia is examined during postnatal rodent development by combining immunocytochemistry (icc) with 3h-thymidine autoradiography (arg) to identify cells in the s phase of the cell cycle. antibodies (abs) which are specific for cells in the oligodendrocyte (ol) lineage were utilized, with emphasis placed upon the proliferation of ols as it remains unclear whether this cell type divides in situ. the results show that proliferating cells stain with abs which are specific ... | 1994 | 7843784 |
| effect of d-ala-d-beta nal-ala-trp-d-phe-lys-nh2 (kp-102) on gh secretion in urethan-anesthetized rats. | the effect of a newly developed growth hormone (gh)-releasing hexapeptide (kp-102) on gh secretion was studied in urethan-anesthetized adult male rats. although kp-102 alone exerted a small influence on gh secretion, it produced a large plasma gh response in the presence of exogenous gh-releasing factor (grf). during the continuous infusion of grf, the somatotropes became refractory to a large bolus dose of grf, but kp-102 induced a marked increase of plasma gh. the gh response to kp-102 alone o ... | 1994 | 7846295 |
| detection, cloning and characterisation of papillomaviral dna present in sarcoid tumours of equus asinus. | molecular investigations on 18 naturally occurring sarcoid tumors removed from donkeys identified papillomaviral dna homologous to bovine papillomavirus (bpv)-2 dna under stringent conditions, in all the samples. restriction endonuclease analysis of 15 of the tumours demonstrated papillomaviral dna similar to bpv-1 and bpv-2. the type of dna was not specific to either the site or the type of lesion. the analysis of the nucleotide base sequence of a cloned papillomaviral element from a sarcoid sh ... | 1994 | 7846835 |
| workshop summary: donkey parasitology. | | 1994 | 7846859 |
| the tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor. | we have previously demonstrated allele loss in hamartomas from patients with tuberous sclerosis for markers spanning the tuberous sclerosis gene on chromosome 16q13.3 (tsc2). germline deletions in the tsc2 gene have been shown in 5% of patients with tuberous sclerosis (tsc). these data support our hypothesis that the tsc2 gene acts as a growth suppressor gene, analogous to the traditional tumour suppressor gene. we now report a tsc hamartoma showing allele loss for markers on chromosome 9q34 in ... | 1994 | 7849709 |
| enhanced sensitivity to neutralizing antibodies in a variant of equine infectious anemia virus is linked to amino acid substitutions in the surface unit envelope glycoprotein. | serial passage of the prototype (pr) cell-adapted wyoming strain of equine infectious anemia virus (eiav) in fetal donkey dermal (fdd) rather than fetal horse (designated fetal equine kidney [fek]) cell cultures resulted in the generation of a variant virus strain which produced accelerated cytopathic effects in fdd cells and was 100- to 1,000-fold more sensitive to neutralizing antibodies than its parent. this neutralization-sensitive variant was designated the fdd strain. although there were d ... | 1995 | 7853482 |
| specific restrictions in the progression of venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins. | the pathogenesis of venezuelan equine encephalitis virus (vee) was examined in the mouse model using v3000, a virus derived from a molecular clone of the trinidad donkey strain of vee. these results were compared in parallel experiments with avirulent mutants of vee derived by site-directed mutagenesis of the clone. adult mice, inoculated subcutaneously in their left rear footpad with v3000, were followed in a time course study for 6 days in which 15 organs were tested for histopathological chan ... | 1995 | 7856110 |
| sequence analyses of the p24 gene of borna disease virus in naturally infected horse, donkey and sheep. | by reverse transcriptase/pcr amplification and subsequent sequence determination of the p24 gene, the relatedness of borna disease virus (bdv) in various naturally infected animal species was determined. these results are indicative of a common ancestral virus pool and a remarkably low species barrier of bdv. comparison of 11 sequences to that of tissue culture adapted virus revealed that the homology among all isolates was at least 96.2% at the nucleotide level, and 97% at the amino acid level. ... | 1994 | 7856315 |
| effect of chronic renal failure on the abundance of mrna for enzymes of intermediary metabolism in kidney and liver. | in chronic renal failure (crf), renal ammoniagenesis and handling of ornithine cycle intermediates (ornithine, citrulline, and arginine) are disturbed. the present study examined the molecular mechanisms of these disturbances in kidney and liver of rats with moderate crf induced by 5/6 nephrectomy. the steady state level of mrna for phosphoenolpyruvate carboxykinase (pepck) and argininosuccinate synthetase (ass) in both kidney and liver were unaffected by crf. on the other hand, that for phospha ... | 1994 | 7859037 |
| children's informed consent to treatment: is the law an ass? | | 1994 | 7861423 |
| the primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin. | two primary serine proteinase inhibitors in goat plasma have been isolated and characterized. the n-terminal sequence analysis of the purified proteins revealed that they are closely related to each other and are highly homologous to human alpha 1-anti-chymotrypsin rather than alpha 1-proteinase inhibitor. however, despite structural similarities the inhibitory specificity of the goat inhibitors differed from each other and from that of anti-chymotrypsin. in contrast with human anti-chymotrypsin ... | 1995 | 7864809 |
| malaria vaccine research. | in our report "activation of raf as a result of recruitment to the plasma membrane" (3 june, p. 1463) (1), panels e and f of figure 1 on page 1464 were incorrect. the correct photographs appear below. in addition, the [see figure in the pdf file] second sentence of the legend to figure 1 should have read, "the raf constructs were tagged at the cooh-terminus with a glu-glu epitope (meympme) (24) for c-raf, or at the nh(2)-terminus with both the glu-glu and the myc (meqkliseedl) (23) epitopes for ... | 1994 | 7864993 |
| ultrastructure of the hinny (equus asinus x equus caballus) seminiferous epithelium. | the gonads and the germinative cells of 3 male hinnies were studied with light and transmission electron microscopy with the aim to observe the development of germ cells and verify the morphological modifications due to the hybridization. the hinny seminiferous epithelium presented sertoli cells and spermatogonia with normal features and anomalous spermatocytes i. the other cells from the spermatogenic sequence were not seen. most of the alterations began to occur in the cytes i, which presented ... | 1994 | 7887486 |
| [hypoglycemic effect of saponin isolated from leaves of acanthopanax senticosus (rupr. et maxin.) harms]. | the hypoglycemic effect of saponin isolated from the leaves of acanthopanax senticosus (ass) was studied. the results showed that ass(100, 200 mg/kg, ip) could decrease various cases of experimental hyperglycemias induced by injection of adrenaline, glucose and alloxan, without affecting the levels of blood sugar in normal mice. | 1994 | 7893389 |
| inhibition of acrosin by serpins. a suicide substrate mechanism. | the serpins antithrombin, protease nexin 1, and alpha 1-antitrypsin with a reactive-center arginine (arg-alpha 1-antitrypsin) were found to inhibit the sperm protease acrosin with varying efficiency. the serpins were titrated against acrosin to determine their specific activity with respect to this enzyme. while antithrombin was fully active against acrosin, more than one molecule of arg-alpha 1-antitrypsin and protease nexin 1 was required to inhibit one molecule of acrosin. in particular, only ... | 1995 | 7893664 |
| osteosynthetic reconstruction in a patient with gardner-diamond syndrome. | based on clinical observations in one female patient who suffered from gardner-diamond syndrome, we noticed that surgery can be performed without any bleeding complications, although operations normally are contraindicated in persons with this condition. additionally, a correlation seems to exist between ass and sexual and hormonal maturity. | 1995 | 7897725 |
| allosteric effects of the alkane-bis-ammonium compound w84 and of tacrine on [3h]pirenzepine binding at m1-receptors in rat cerebral cortex. | the bis-quaternary w84, hexamethylene-bis-[dimethyl-(3-phthalimidopropyl)-ammonium bromide], is a potent allosteric modulator of m2-cholinoceptors. in this study we aimed at quantifying its allosteric effect on the dissociation of [3h]pirenzepine from m1-cholinoceptors in rat cerebral cortex and to measure the effects on association and equilibrium binding of [3h]pirenzepine. for sake of comparison tacrine was included which is known to be a potent allosteric modulator of [3h]pirenzepine binding ... | 1994 | 7899262 |
| characterization of chromosome 9 deletions in transitional cell carcinoma by microsatellite assay. | a panel of 18 superficial or invasive transitional cell carcinomas (tccs) was analyzed for chromosome 9 deletions by performing a high-density loss of heterozygosity (loh) analysis. twenty-five microsatellite loci were assayed by the polymerase chain reaction (pcr) and 7 restriction fragment length polymorphism (rflp) loci were analyzed by southern blotting. concordant results were obtained with these methods, including direct comparisons at 2 loci. chromosome 9 loh was observed in 13 (72%) of 1 ... | 1993 | 7902161 |
| frequency of trypanosomosis and gastrointestinal parasites in draught donkeys in the gambia in relation to animal husbandry. | prevalence of trypanosomosis, gastrointestinal strongyles and level of strongyle egg outputs were studied in relation to husbandry practices in the draught donkey population in the gambia. feeding regime, number of working hours per day and overnight penning practices of donkeys affected significantly (p < 0.05) the level of gastrointestinal strongyle egg output, but not (p > 0.05) trypanosomosis prevalence. dual trypanosome and gastrointestinal strongyle infection significantly reduced the pcv ... | 1994 | 7941024 |
| bodyweight changes in pregnant and lactating donkey mares and their foals. | | 1994 | 7941264 |