| effect of guglielmi detachable coils on experimental carotid artery aneurysms in primates. | clinical experience has established that intravascularly placed metal coils can be a useful treatment for cerebral vascular aneurysms. however, the mechanism by which the coils induce occlusion of the aneurysm is unclear. appropriate use of this promising treatment modality requires basic understanding of the occlusive process. we used an animal model system of experimentally induced carotid aneurysms to investigate the initial events induced by guglielmi detachable coils (gdcs), as well as the ... | 1995 | 7482653 |
| effect of guglielmi detachable coils on experimental carotid artery aneurysms in primates. | clinical experience has established that intravascularly placed metal coils can be a useful treatment for cerebral vascular aneurysms. however, the mechanism by which the coils induce occlusion of the aneurysm is unclear. appropriate use of this promising treatment modality requires basic understanding of the occlusive process. we used an animal model system of experimentally induced carotid aneurysms to investigate the initial events induced by guglielmi detachable coils (gdcs), as well as the ... | 1995 | 7482653 |
| comparative changes in microvasculature and bone during healing of implant and extraction sites. | the acquisition and maintenance of biological fixation of dental implants are achieved by a rapid and regenerative response of the recipient tissues, especially the vascular and osseous elements. this sequential response is described from initial osteogenesis through remodeling up to 20 weeks after implantation in macaca fuscata monkeys. the sequential changes in the microvasculature and bone formation in three-dimensional bone-vasculature microcorrosion casts are studied by means of a plastic i ... | 1993 | 7509882 |
| nitric oxide synthase immunoreactivity colocalized with nadph-diaphorase histochemistry in monkey cerebral cortex. | the distributions of reduced nicotinamide adenine dinucleotide phosphate-diaphorase (nadph-d) and nitric oxide synthase (nos) containing neurons and the extent of nadph-d and nos colocalization have been analyzed by histochemical and immunocytochemical techniques in the neocortex of macaca fuscata monkeys. nadph-d positive cells were consistently also nos positive and presented a relatively uniform distribution from area to area, but area-specific differences were observed in the pattern of dist ... | 1994 | 7516813 |
| cardiac xenotransplantation from pig to japanese monkey with splenectomy, tacrolims, filtration plasmapheresis, and nafamstat mesilate. | | 1994 | 7518105 |
| thermal damage threshold of brain tissue--histological study of heated normal monkey brains. | the thermal damage threshold of normal brain tissue was evaluated from immediate and delayed histological changes caused by hyperthermia treatment of normal monkey (macaca fuscata) brains. a 2450 mhz microwave antenna and an antenna cooling system devised by our group were used for interstitial hyperthermia treatment. the antenna within the cooling system was inserted through a small craniectomy under general anesthesia. the temperature at a reference point, 4 mm radially away from the surface o ... | 1994 | 7520542 |
| retinogeniculate projection fibers in the monkey optic chiasm: a demonstration of the fiber arrangement by means of wheat germ agglutinin conjugated to horseradish peroxidase. | the fiber arrangement of the retinogeniculate pathway was investigated in the chiasm of japanese monkeys (macaca fuscata) by an iontophoretic injection of wheat germ agglutinin conjugated to horseradish peroxidase into the lateral geniculate nucleus (lgn). it has been claimed that there is a distinct retinotopy in the monkey chiasm, despite lack of any clear anatomical evidence. however, the present data indicate a rather gross retinotopy or almost no discernible retinotopy. fibers from the fove ... | 1994 | 7527062 |
| retinogeniculate projection fibers in the monkey optic chiasm: a demonstration of the fiber arrangement by means of wheat germ agglutinin conjugated to horseradish peroxidase. | the fiber arrangement of the retinogeniculate pathway was investigated in the chiasm of japanese monkeys (macaca fuscata) by an iontophoretic injection of wheat germ agglutinin conjugated to horseradish peroxidase into the lateral geniculate nucleus (lgn). it has been claimed that there is a distinct retinotopy in the monkey chiasm, despite lack of any clear anatomical evidence. however, the present data indicate a rather gross retinotopy or almost no discernible retinotopy. fibers from the fove ... | 1994 | 7527062 |
| acute effects of interstitial hyperthermia on normal monkey brain--magnetic resonance imaging appearance and effects on blood-brain barrier. | the magnitude and time course of histological and neuroradiological changes due to interstitial hyperthermia in normal cerebral white matter were investigated in eight adult japanese monkeys. a cooling system enveloping a 2450-mhz microwave antenna was inserted stereotactically into the brain under general anesthesia. a point located 5 mm away from the surface of the cooling system was used as the reference point (rp). hyperthermia was given to maintain the rp at 43 degrees c for 60 minutes. two ... | 1994 | 7529367 |
| acute effects of interstitial hyperthermia on normal monkey brain--magnetic resonance imaging appearance and effects on blood-brain barrier. | the magnitude and time course of histological and neuroradiological changes due to interstitial hyperthermia in normal cerebral white matter were investigated in eight adult japanese monkeys. a cooling system enveloping a 2450-mhz microwave antenna was inserted stereotactically into the brain under general anesthesia. a point located 5 mm away from the surface of the cooling system was used as the reference point (rp). hyperthermia was given to maintain the rp at 43 degrees c for 60 minutes. two ... | 1994 | 7529367 |
| the effects of patients' sera with sperm-immobilizing antibodies on sperm of the japanese monkey. | in order to study the interspecies cross-reactivity of sperm-immobilizing antibodies found in sera of women who were infertile for unknown reasons, we used the sperm-immobilization test to examine the effects of patients' sera with or without sperm-immobilizing antibodies on the sperm of the japanese monkey (macaca fuscata). fourteen of 17 antibody-positive sera and 7 of 14 antibody-negative sera showed sperm-immobilizing activity with regard to monkey sperm. the sperm-immobilizing antibody that ... | 1994 | 7530441 |
| projections from the globus pallidus to the thalamic areas projecting to the dorsal area 6 of the macaque monkey: a multiple tracing study. | in the brains of 3 japanese monkeys (macaca fuscata), a combined injection of the tract-tracers fast blue (fb), diamidino yellow (dy), and horseradish peroxidase-conjugated with wheat germ agglutinin (wga-hrp) was performed: the retrograde tracers, fb and dy, were injected into a rostral and a caudal sectors of the dorsal part in area 6, and the anterograde tracer, wga-hrp, was injected into the internal segment of the globus pallidus (gpi). in the thalamus, fb- and dy-labeled neurons were distr ... | 1994 | 7535405 |
| projections from the globus pallidus to the thalamic areas projecting to the dorsal area 6 of the macaque monkey: a multiple tracing study. | in the brains of 3 japanese monkeys (macaca fuscata), a combined injection of the tract-tracers fast blue (fb), diamidino yellow (dy), and horseradish peroxidase-conjugated with wheat germ agglutinin (wga-hrp) was performed: the retrograde tracers, fb and dy, were injected into a rostral and a caudal sectors of the dorsal part in area 6, and the anterograde tracer, wga-hrp, was injected into the internal segment of the globus pallidus (gpi). in the thalamus, fb- and dy-labeled neurons were distr ... | 1994 | 7535405 |
| ipsilateral connections of the anterior cingulate cortex with the frontal and medial temporal cortices in the macaque monkey. | the present study was attempted to study ipsilateral corticocortical connections of the anterior part (area 24) of the cingulate cortex of the macaque monkey by means of wheat germ agglutinin-conjugated peroxidase (wga-hrp) method. in 2 out of 4 japanese monkeys (macaca fuscata) that were injected with wga-hrp into the anterior part of the cingulate cortex, the sites of injection were successfully localized within the cortical regions corresponding to areas 24a and 24b. the results obtained from ... | 1994 | 7535904 |
| ipsilateral connections of the anterior cingulate cortex with the frontal and medial temporal cortices in the macaque monkey. | the present study was attempted to study ipsilateral corticocortical connections of the anterior part (area 24) of the cingulate cortex of the macaque monkey by means of wheat germ agglutinin-conjugated peroxidase (wga-hrp) method. in 2 out of 4 japanese monkeys (macaca fuscata) that were injected with wga-hrp into the anterior part of the cingulate cortex, the sites of injection were successfully localized within the cortical regions corresponding to areas 24a and 24b. the results obtained from ... | 1994 | 7535904 |
| immune recognition of genetically diverse simian t-cell lymphotropic virus type i isolates. | nucleotide sequence analysis of selected regions of the gag, pol, env and px genes of simian t-cell lymphotropic virus type i (stlv-i) strains indicated that african isolates were more closely related to human t-cell lymphotropic virus type i (htlv-i) than asian isolates. despite these recent comparative studies on nucleotide sequence homology between htlv-i and stlv-i isolates, only limited information is available regarding the influence of genetic differences on antigen-antibody recognition o ... | 1995 | 7535998 |
| odontoameloblastoma in a japanese monkey (macaca fuscata). | | 1995 | 7536982 |
| thalamic distribution of projection neurons to the primary motor cortex relative to afferent terminal fields from the globus pallidus in the macaque monkey. | to examine quantitatively the pathway from the internal segment of the globus pallidus to the primary motor cortex through the thalamus, we compared the distribution of thalamocortical neurons projecting to the motor cortex with the distribution of afferent terminal fields from the pallidum in the ventrolateral nuclear group of the thalamus in four japanese monkeys by using the anterograde and retrograde double-labeling method. in each monkey, different fluorescent retrograde tracers (fast blue ... | 1995 | 7538516 |
| thalamic distribution of projection neurons to the primary motor cortex relative to afferent terminal fields from the globus pallidus in the macaque monkey. | to examine quantitatively the pathway from the internal segment of the globus pallidus to the primary motor cortex through the thalamus, we compared the distribution of thalamocortical neurons projecting to the motor cortex with the distribution of afferent terminal fields from the pallidum in the ventrolateral nuclear group of the thalamus in four japanese monkeys by using the anterograde and retrograde double-labeling method. in each monkey, different fluorescent retrograde tracers (fast blue ... | 1995 | 7538516 |
| functional and histopathologic studies of primate pulmonary allografts preserved for 24 hours with a form of modified extracellular solution. | the purpose of this investigation was to evaluate the efficacy of a solution (ep4) for long-term hypothermic pulmonary allograft preservation in a primate model using both functional and histopathologic criteria. | 1995 | 7544618 |
| functional and histopathologic studies of primate pulmonary allografts preserved for 24 hours with a form of modified extracellular solution. | the purpose of this investigation was to evaluate the efficacy of a solution (ep4) for long-term hypothermic pulmonary allograft preservation in a primate model using both functional and histopathologic criteria. | 1995 | 7544618 |
| effects of helicobacter pylori infection on gastric mucosal defense factors in japanese monkeys. | the pathogenic role played by helicobacter pylori in gastric mucosal defense was investigated in japanese monkeys infected with h. pylori. serum gastrin levels and ammonia concentrations in gastric juice were compared in h. pylori-infected (n = 6) and control (n = 7) groups. the gastritis score, the intracellular content of periodic acid-schiff (pas)-positive substance and hexosamine, and the bromodeoxyuridine (brdu) labeling index in the gastric mucosa were compared in the two groups in the ant ... | 1995 | 7550852 |
| effects of helicobacter pylori infection on gastric mucosal defense factors in japanese monkeys. | the pathogenic role played by helicobacter pylori in gastric mucosal defense was investigated in japanese monkeys infected with h. pylori. serum gastrin levels and ammonia concentrations in gastric juice were compared in h. pylori-infected (n = 6) and control (n = 7) groups. the gastritis score, the intracellular content of periodic acid-schiff (pas)-positive substance and hexosamine, and the bromodeoxyuridine (brdu) labeling index in the gastric mucosa were compared in the two groups in the ant ... | 1995 | 7550852 |
| expression of basement membrane components in the dental papilla mesenchyme of monkey tooth germs--an immunohistochemical study. | the present work, which employs indirect immunoperoxidase methods, demonstrates electron microscopic localization of three major basement membrane (bm) components--type iv collagen, laminin, and heparan sulfate proteoglycan--at the early stages of odontogenesis in tooth germs of the japanese macaque (macaca fuscata). intense immunostaining for each examined component occurred at the interface between the inner enamel epithelium and the dental papilla mesenchyme. at higher magnification, immunore ... | 1995 | 7554936 |
| variations in the thoracic duct of the japanese monkey (macaca fuscata). | variations in the thoracic duct of japanese monkeys were compared with previous reports on the human (japanese) thoracic duct. the most striking difference between man and the japanese monkey was that in the majority of the monkeys examined the right thoracic duct ascended without crossing to the left side whereas in man the upper portion of the right duct crosses over to the left. although most thoracic ducts in man, other primates and domestic animals reportedly enter the left venous angle, ab ... | 1994 | 7559113 |
| variations in the thoracic duct of the japanese monkey (macaca fuscata). | variations in the thoracic duct of japanese monkeys were compared with previous reports on the human (japanese) thoracic duct. the most striking difference between man and the japanese monkey was that in the majority of the monkeys examined the right thoracic duct ascended without crossing to the left side whereas in man the upper portion of the right duct crosses over to the left. although most thoracic ducts in man, other primates and domestic animals reportedly enter the left venous angle, ab ... | 1994 | 7559113 |
| 192ir induced radiation damage in monkey brain assessed with magnetic resonance imaging and histological examination. | the effects of irradiation on a large volume of normal brain tissue as occurs in interstitial brachytherapy were investigated. double iridium-192 seed assemblies were stereotactically implanted into the right centrum semiovale of eight adult japanese monkeys (macaca fuscata). the morphological changes induced in the normal brain tissue were evaluated with magnetic resonance (mr) imaging with and without gadolinium-diethylenetriaminepenta-acetic acid (gd) enhancement at 2 days and 1, 3, and 6 mon ... | 1995 | 7566396 |
| 192ir induced radiation damage in monkey brain assessed with magnetic resonance imaging and histological examination. | the effects of irradiation on a large volume of normal brain tissue as occurs in interstitial brachytherapy were investigated. double iridium-192 seed assemblies were stereotactically implanted into the right centrum semiovale of eight adult japanese monkeys (macaca fuscata). the morphological changes induced in the normal brain tissue were evaluated with magnetic resonance (mr) imaging with and without gadolinium-diethylenetriaminepenta-acetic acid (gd) enhancement at 2 days and 1, 3, and 6 mon ... | 1995 | 7566396 |
| morphology of the nerve terminals of laryngeal muscles in the japanese monkey (macaca fuscata). | laryngeal muscles, namely, the cricothyroid (ct), lateral crico-arytenoid (lca), thyrio-arytenoid (ta), posterior crio-arytenoid (pca), interarytenoid (ia) muscles, of japanese monkeys (body weight, 4.4-8.3 kg; 3-10 years old, male) were examined histologically and by light and scanning electron microscopy. the diameter of muscle fibres with nerve terminals in the ct of the japanese monkey was larger than that of other laryngeal muscles. however, the areas of nerve terminals varied among larynge ... | 1995 | 7566875 |
| morphology of the nerve terminals of laryngeal muscles in the japanese monkey (macaca fuscata). | laryngeal muscles, namely, the cricothyroid (ct), lateral crico-arytenoid (lca), thyrio-arytenoid (ta), posterior crio-arytenoid (pca), interarytenoid (ia) muscles, of japanese monkeys (body weight, 4.4-8.3 kg; 3-10 years old, male) were examined histologically and by light and scanning electron microscopy. the diameter of muscle fibres with nerve terminals in the ct of the japanese monkey was larger than that of other laryngeal muscles. however, the areas of nerve terminals varied among larynge ... | 1995 | 7566875 |
| rosette formation by plasmodium coatneyi-infected erythrocytes of the japanese macaque (macaca fuscata). | we studied in vitro the spontaneous rosette formation by red blood cells of a japanese macaque infected with plasmodium coatneyi, which occurred after 30 hr of incubation. rosette formation involved 88% of parasitized red blood cells (prbcs). spontaneous rosettes were formed when the ring-stage parasites developed into late trophozoites or schizonts. a rosette usually consisted of a prbc surrounded by three or more uninfected erythrocytes. electron microscopic examination revealed that interacti ... | 1995 | 7573716 |
| analysis of the expression and the first exon of aromatase mrna in monkey brain. | to elucidate the mechanism of the region-specific expression of the aromatase in the primate brain, we investigated the distribution and level of the total aromatase mrna and the aromatase mrna with the exon 1-f, which was reported to be the brain-specific exon 1 of the human aromatase gene, in male japanese monkeys. total rnas extracted from the hypothalamus-preoptic area (hpoa), amygdala (amy), cerebellum, hippocampus, brainstem, five regions of cerebral cortex and four peripheral tissues: liv ... | 1995 | 7577717 |
| analysis of the expression and the first exon of aromatase mrna in monkey brain. | to elucidate the mechanism of the region-specific expression of the aromatase in the primate brain, we investigated the distribution and level of the total aromatase mrna and the aromatase mrna with the exon 1-f, which was reported to be the brain-specific exon 1 of the human aromatase gene, in male japanese monkeys. total rnas extracted from the hypothalamus-preoptic area (hpoa), amygdala (amy), cerebellum, hippocampus, brainstem, five regions of cerebral cortex and four peripheral tissues: liv ... | 1995 | 7577717 |
| immunocytochemical localization of l-alpha-hydroxyacid oxidase in dense bar of dumb-bell-shaped peroxisomes of monkey kidney. | localization of the b of l-alpha hydroxyacid oxidase (hox-b) in monkey kidney peroxisomes was investigated by immunoelectron microscopic techniques. kidneys of japanese monkeys, macaca fuscata, were fixed with 4% paraformaldehyde + 0.25% glutaraldehyde and embedded in lr white resin. thin sections were stained for hox-b and catalase by the immunogold technique. hox-b was localized in the marginal plates of normal peroxisomes and the dense bar of dumb-bell-shaped peroxisomes. catalase was detecte ... | 1995 | 7584560 |
| immunocytochemical localization of l-alpha-hydroxyacid oxidase in dense bar of dumb-bell-shaped peroxisomes of monkey kidney. | localization of the b of l-alpha hydroxyacid oxidase (hox-b) in monkey kidney peroxisomes was investigated by immunoelectron microscopic techniques. kidneys of japanese monkeys, macaca fuscata, were fixed with 4% paraformaldehyde + 0.25% glutaraldehyde and embedded in lr white resin. thin sections were stained for hox-b and catalase by the immunogold technique. hox-b was localized in the marginal plates of normal peroxisomes and the dense bar of dumb-bell-shaped peroxisomes. catalase was detecte ... | 1995 | 7584560 |
| lipid profiles of cerebral gray matter and livers of macaque monkeys macaca fascicularis and macaca fuscata fuscata: a comparative study during development. | the lipid and fatty acid profiles in cerebral gray matter and livers were studied in macaque monkeys (macaca fascicularis and m. fuscata fuscata) of different ages. in cerebral gray matter, the phosphatidylcholine/phosphatidylethanolamine (pc/pe) ratio decreased in animals more than 3 years old, while the cholesterol/lipid-phosphorus ratios and the unsaturation indices increased, as compared with those in fetuses and newborns. the level of 22:6n-3 in pe of cerebral gray matter increased up to 3 ... | 1995 | 7599973 |
| basal cell tumor in a japanese macaque (macaca fuscata). | a rare case of basal cell tumor of the skin in a wild-caught female japanese macaque (macaca fuscata) was studied. tumor growth, which was composed of cells resembling basal cells, was observed in the dermis and subcutis and showed a mixture of ribbon, solid, glandular, and cystic patterns. the tumor was separated from surrounding normal tissue by a compressed zone of fibrous connective tissue. the nuclei were round and hyperchromatic and possessed a single centrally located nucleolus. mitotic f ... | 1995 | 7604501 |
| reproductive senescence in female japanese monkeys (macaca fuscata): age- and season-related changes in hypothalamic-pituitary-ovarian functions and fecundity rates. | age- and season-related changes in gonadotropin-gonadal functions were studied in captive female japanese monkeys (macaca fuscata fuscata), with special reference to reproductive senescence. in experiment 1, a total of 57 nonlactating females at ages 3-32 yr were used. blood samples were collected for at least one breeding season (september through march), and changes in plasma concentrations of lh, estradiol, and progesterone were examined. in experiment 2, two groups of females (older females, ... | 1995 | 7632833 |
| reproductive senescence in female japanese monkeys (macaca fuscata): age- and season-related changes in hypothalamic-pituitary-ovarian functions and fecundity rates. | age- and season-related changes in gonadotropin-gonadal functions were studied in captive female japanese monkeys (macaca fuscata fuscata), with special reference to reproductive senescence. in experiment 1, a total of 57 nonlactating females at ages 3-32 yr were used. blood samples were collected for at least one breeding season (september through march), and changes in plasma concentrations of lh, estradiol, and progesterone were examined. in experiment 2, two groups of females (older females, ... | 1995 | 7632833 |
| postcranial skeleton of a macaque trained for bipedal standing and walking and implications for functional adaptation. | the postcranial skeleton of a japanese macaque that had been trained for bipedalism over an 11-year period was studied. considerable modifications in the hindlimb bones caused by bipedal postural and locomotor behaviour were observed. changes occurred in joint morphology, articular dimensions and shape-dependent strength of long bones, reflecting the causal relationship between function and morphology. however, the conditions under which the modifications are developed are somewhat different fro ... | 1995 | 7665119 |
| cortical connections of the motor thalamic nuclei in the japanese monkey, macaca fuscata. | our findings revealed the nucleus ventralis lateralis pars oralis (vlo) projection to motor area, and the nucleus ventralis anterior pars principalis (vapc) projections to the premotor and supplementary motor areas (sma). the vlo gave rise to thalamocortical projections terminating in the superficial half of layer i, mainly in the forelimb motor area. the vapc gave rise to the superficial projections to the post-arcuate premotor area around the arcuate genu and arcuate spur as well as sma. we su ... | 1993 | 7685538 |
| [the immunosuppressive effects of fk506 on single lung allotransplantation in japanese monkey (macaca fuscata)]. | allotransplanted lung of japanese monkey (macaca fuscata) was studied in view of immunosuppressive effects of fk506. left lung grafts were transplanted orthotopically. according to the postoperative treatment, recipients were divided into two groups. group a (n = 7): fk506 0.5 mg/kg/day intramuscularly up to the 6th postoperative day (pod) and 0.15 mg/kg/day thereafter, and group b (n = 7): no immunosuppressive drugs. chest radiographs, hematoxylin-eosin staining and immunostaining of the grafte ... | 1993 | 7690829 |
| superior cervical ganglionic origin of sympathetic fibers in the facial nerve, and their preganglionic spinal inputs: a wga-hrp study in macaca fuscata. | the origin of sympathetic fibers in the facial nerve of macaca fuscata was demonstrated using the hrp method. wga-hrp injection into the facial nerve resulted in heavy labeling in the ipsilateral superior cervical ganglion. the majority of labeled neurons in the superior cervical ganglion had sizes ranging from 20 to 35 microns. in the present study it was of particular interest that labeled neurons are also found in the intermediolateral nucleus and lateral funiculus ipsilaterally at the level ... | 1993 | 7693309 |
| microvascular pattern of the retina in the japanese monkey (macaca fuscata fuscata). | the microvascular architecture of the retina in the japanese monkey was revealed using scanning electron microscopy of microvascular corrosion casts. at the optic nerve disc, the central retinal artery radiated to four primary retinal arterioles: the superior and inferior temporal arterioles and superior and inferior nasal arterioles. a dense retinal capillary network showed regional differences in density. the capillary networks observed were divided in four parts: the optic nerve disc, macula, ... | 1994 | 7701308 |
| prevalence of ige antibody to crude and purified allergens of japanese cedar pollen among different troops of japanese monkeys (macaca fuscata). | we measured specific ige antibodies to the crude allergen as well as two purified allergens (cry j i and cry j ii) of japanese cedar (cryptomeria japonica--cj) pollen in the serum of 276 japanese monkeys in nine troops. of 45 monkeys with cj specific ige in eight of nine troops, 23 (51%) were found to have ige to both cry j i and cry j ii, 21 (47%) only to cry j i, and one (2.2%) only to cry j ii. the positive rate of specific ige antibody to each allergen varied among the troops. | 1994 | 7731029 |
| prevalence of ige antibody to crude and purified allergens of japanese cedar pollen among different troops of japanese monkeys (macaca fuscata). | we measured specific ige antibodies to the crude allergen as well as two purified allergens (cry j i and cry j ii) of japanese cedar (cryptomeria japonica--cj) pollen in the serum of 276 japanese monkeys in nine troops. of 45 monkeys with cj specific ige in eight of nine troops, 23 (51%) were found to have ige to both cry j i and cry j ii, 21 (47%) only to cry j i, and one (2.2%) only to cry j ii. the positive rate of specific ige antibody to each allergen varied among the troops. | 1994 | 7731029 |
| establishment of an animal model for chronic gastritis with helicobacter pylori: potential model for long-term observations. | to assess the suitability of an established experimental model for chronic gastritis associated with helicobacter pylori for use in long-term observations. | 1994 | 7735940 |
| establishment of an animal model for chronic gastritis with helicobacter pylori: potential model for long-term observations. | to assess the suitability of an established experimental model for chronic gastritis associated with helicobacter pylori for use in long-term observations. | 1994 | 7735940 |
| nitroxidergic innervation in dog and monkey renal arteries. | we analyzed mechanisms underlying neurogenic vasodilatation in dog and japanese monkey renal arteries. isometric mechanical responses of the arterial strip to nerve stimulation by nicotine were recorded. nicotine-induced contractions were abolished by hexamethonium and potentiated by ng-nitro-l-arginine, a nitric oxide synthase inhibitor. the potentiating effect was reversed by l-arginine. ng-nitro-l-arginine did not potentiate the contraction caused by norepinephrine. the nicotine-induced contr ... | 1995 | 7737721 |
| do retinal ganglion cells project bilaterally in ground squirrels? | bilaterally projecting retinal ganglion cells have recently been reported in the japanese monkey macaca fuscata and albino rat. in the present experiments, we sought to determine whether ganglion cells project bilaterally in the 13-lined ground squirrel spermophilus tridecemlineatus. we injected rhodamine-conjugated latex microspheres (red beads) into the right optic tract, superior colliculus and the dorsal lateral geniculate nucleus and fitc-conjugated latex microspheres (green beads) into the ... | 1995 | 7757471 |
| subclinical renal oxalosis in wild-caught japanese macaques (macaca fuscata). | various degrees of crystal deposition were found in the kidneys of 12 out of 59 japanese macaques (macaca fuscata) caught in the wild in gifu, japan. the needle- or rod-shaped crystals, which were radially arranged and occurred in the lumen and epithelium of the renal (mainly the proximal) tubules, were birefringent under polarized light. they stained with alizarin red s at a ph of 7.0 but not 4.2, and were identified as calcium oxalate. the morphological features of the renal lesions were simil ... | 1995 | 7769143 |
| comparative mapping of the immunoglobulin c epsilon 1 gene (ighe) in five species of nonhuman primates by fluorescence in situ hybridization. | the orthologous immunoglobulin c epsilon 1 gene (ighe) of the common chimpanzee, pygmy chimpanzee, orangutan, white-handed gibbon, and japanese macaque was assigned to the human chromosome 14 homologue in each species and regionally mapped by fluorescence in situ hybridization to ptr15q32 (common chimpanzee), ppa15q32 (pygmy chimpanzee), ppy15q32 (orangutan), hla17qter (white-handed gibbon), and mfu7q29 (japanese macaque). the gene localized to the terminal region of the chromosome in each speci ... | 1995 | 7789180 |
| evolution of alanine:glyoxylate aminotransferase 1 peroxisomal and mitochondrial targeting. a survey of its subcellular distribution in the livers of various representatives of the classes mammalia, aves and amphibia. | as part of a wider study on the molecular evolution of alanine:glyoxylate aminotransferase 1 (agt1) intracellular compartmentalization, we have determined the subcellular distribution of immunoreactive agt1, using postembedding protein a-gold immunoelectron microscopy, in the livers of various members of the classes mammalia, aves, and amphibia. as far as organellar distribution is concerned, three categories could be distinguished. in members of the first category (type i), all, or nearly all, ... | 1994 | 7813517 |
| phylogenetic relationships among homo sapiens and related species based on restriction site variations in rdna spacers. | a rapid method, using 12 restriction enzymes, was employed to analyze variations in ribosomal dna (rdna) spacers in a study of phylogenetic relationships between homo sapiens and related species. we mapped restriction sites in the external and internal spacer regions and compared the arrangements of sites. the estimated sequence divergence between homo sapiens and pan troglodytes, pan paniscus, gorilla gorilla, pongo pygmaeus, hylobates lar, h. agilis, and macaca fuscata was 2.7, 2.3, 3.8, 7.3, ... | 1994 | 7826313 |
| up-regulation of hepatic ldl receptor gene expression by monatepil, a novel calcium antagonist, in high cholesterol diet-fed japanese monkeys. | the action of the novel antihypertensive calcium antagonist monatepil on the hepatic ldl receptor was investigated at the gene expression level to clarify the mechanism of its hypolipidemic effect. in cholesterol-fed control monkeys, the ldl receptor mrna level decreased to approximately 30% of that in the normal diet-fed monkeys. however, the administration of monatepil increased ldl receptor mrna to normal levels (three- to fourfold stimulation). it is suggested that monatepil raises the numbe ... | 1994 | 7848617 |
| up-regulation of hepatic ldl receptor gene expression by monatepil, a novel calcium antagonist, in high cholesterol diet-fed japanese monkeys. | the action of the novel antihypertensive calcium antagonist monatepil on the hepatic ldl receptor was investigated at the gene expression level to clarify the mechanism of its hypolipidemic effect. in cholesterol-fed control monkeys, the ldl receptor mrna level decreased to approximately 30% of that in the normal diet-fed monkeys. however, the administration of monatepil increased ldl receptor mrna to normal levels (three- to fourfold stimulation). it is suggested that monatepil raises the numbe ... | 1994 | 7848617 |
| characterization of the fibrillar layer at the epithelial-mesenchymal junction in tooth germs. | a characteristic layer containing numerous fibrils is associated with the basement membrane of the inner enamel epithelium during the early stages of odontogenesis. however, its nature is not well understood. in this study, the layer was examined with high-resolution electron microscopy and immuno-histochemical staining. tooth germs of monkeys (macaca fuscata) were studied and each fibril in the layer was found to be a tubular structure, 8-9 nm in width, resembling a "basotubule", the tubular st ... | 1994 | 7850866 |
| the novel anti-ulcer agent ecabet sodium (ta-2711) eradicates helicobacter pylori colonizing on the gastric mucosa of japanese monkeys. | | 1994 | 7871373 |
| the novel anti-ulcer agent ecabet sodium (ta-2711) eradicates helicobacter pylori colonizing on the gastric mucosa of japanese monkeys. | | 1994 | 7871373 |
| [anatomical studies on the thumb muscles of the human hand]. | the thenar muscles in 34 cases of 25 human adults were dissected using a stereoscopic microscope. the main supplying branch of the median nerve is often called the recurrent branch because of its characteristic recurrent course, and it enters the muscles between the abductor pollicis brevis and the superficial head of the flexor pollicis brevis. the other branch of the median nerve enters the latter muscle directly close to the tendon of the flexor pollicis longus laterally. this is called the d ... | 1994 | 7887125 |
| localization and quantitation of active renin in monkey kidney by radioinhibitor binding and in vitro autoradiography. | we developed an in vitro autoradiographic method to localize and quantify active renin in primate tissues. active renin in monkey kidney sections was labeled with the primate specific renin inhibitor, 3h-cgp29287, and quantitated with autoradiography and computerized densitometry. microscopic emulsion autoradiography was carried out to clarify the detailed localization of the binding. non-specific binding to aspartyl proteases other than renin was blocked using 1 mumol/l of n-acetyl-pepstatin. t ... | 1994 | 7917151 |
| variations in fundamental frequency peak position in japanese macaque (macaca fuscata) coo calls. | japanese macaques (macaca fuscata) produce coo calls whose use in various contexts is correlated with differences in the relative temporal position of the peak value of a call's fundamental frequency (green, 1975). studies have produced conflicting results about both the location of the category boundary between smooth early high and smooth late high coo subtypes and macaques' perceptual sensitivity to variations in peak position. in this study, fundamental frequency peak positions were measured ... | 1994 | 7924259 |
| [hypothalamo-pituitary-testicular function in male japanese monkeys (macaca fuscata) in non-mating season]. | we examined seasonal changes in serum testosterone and lh, and investigated mechanisms of reduction of testicular function in non-mating season in male japanese monkeys. blood samples were collected monthly throughout one year in 5 males, and hcg and lh-rh were administered to 5 and 3 animals, respectively, in non-mating and mating season. serum testosterone and lh were measured by ria. serum testosterone showed the obvious seasonal changes, being low in march to august and high in october to fe ... | 1994 | 7925626 |
| [hypothalamo-pituitary-testicular function in male japanese monkeys (macaca fuscata) in non-mating season]. | we examined seasonal changes in serum testosterone and lh, and investigated mechanisms of reduction of testicular function in non-mating season in male japanese monkeys. blood samples were collected monthly throughout one year in 5 males, and hcg and lh-rh were administered to 5 and 3 animals, respectively, in non-mating and mating season. serum testosterone and lh were measured by ria. serum testosterone showed the obvious seasonal changes, being low in march to august and high in october to fe ... | 1994 | 7925626 |
| expression of hepatocyte growth factor in normal and carbon tetrachloride-treated monkeys. | we examined hepatocyte growth factor-producing organs in normal and carbon tetrachloride-treated japanese monkeys, a species more related to human beings than rats, by measuring hepatocyte growth factor protein and hepatocyte growth factor mrna in various tissues. hepatocyte growth factor protein and hepatocyte growth factor mrna levels were determined by use of an enzyme-linked immunosorbent assay for human hepatocyte growth factor and northern-blot analysis using human hepatocyte growth factor ... | 1994 | 7927260 |
| expression of hepatocyte growth factor in normal and carbon tetrachloride-treated monkeys. | we examined hepatocyte growth factor-producing organs in normal and carbon tetrachloride-treated japanese monkeys, a species more related to human beings than rats, by measuring hepatocyte growth factor protein and hepatocyte growth factor mrna in various tissues. hepatocyte growth factor protein and hepatocyte growth factor mrna levels were determined by use of an enzyme-linked immunosorbent assay for human hepatocyte growth factor and northern-blot analysis using human hepatocyte growth factor ... | 1994 | 7927260 |
| identification and characterization of a 27 kda acrosome protein of human sperm defined by a monoclonal antibody with fertilization-blocking effect. | a monoclonal antibody, mab 1g1, possessing a strong fertilization-blocking activity was prepared by immunizing a balb/c mouse with capacitated human sperm in order to study the molecular nature of sperm antigens relevant to fertilization. mab 1g1 inhibited human sperm penetration into zona-free hamster eggs. it reacted to the apical portion of acrosome-reacted human sperm, but did not react to live sperm before the acrosome reaction as demonstrated by immunofluorescence staining. in paraffin-emb ... | 1994 | 7932391 |
| cervical ripening and uterine contraction induced by prostaglandin e2-gel in pregnant japanese monkeys (macaca fuscata fuscata). | effects of intracervical administration of pge2-gel were studied in pregnant japanese monkeys (macaca fuscata fuscata) near term. administration of pge2-gel induced cervical ripening and an increase in maternal plasma pge2 but no change in pgf2 alpha. ultrastructural observations of the connective tissue of the cervix after pge2-gel treatment revealed a decrease in the number of collagenous fibers. these results show that intracervical administration of pge2-gel induces cervical ripening without ... | 1994 | 7932635 |
| cervical ripening and uterine contraction induced by prostaglandin e2-gel in pregnant japanese monkeys (macaca fuscata fuscata). | effects of intracervical administration of pge2-gel were studied in pregnant japanese monkeys (macaca fuscata fuscata) near term. administration of pge2-gel induced cervical ripening and an increase in maternal plasma pge2 but no change in pgf2 alpha. ultrastructural observations of the connective tissue of the cervix after pge2-gel treatment revealed a decrease in the number of collagenous fibers. these results show that intracervical administration of pge2-gel induces cervical ripening without ... | 1994 | 7932635 |
| localized silicon distribution in supragingival calculus from japanese monkeys (macaca fuscata). | using an electron-probe microanalyser, the distribution of silicon and other elements in supragingival dental calculus in domestic japanese monkeys (macaca fuscata) was studied. in two out of four monkeys kept in animals centres, a localized silicon distribution was found in both fracture and oral surfaces of the calculi. the silicon-rich area consisting of silicon alone resembled opal, but the areas containing silicon and other metal ions such as magnesium, aluminium, potassium and iron resembl ... | 1994 | 7945018 |
| localized silicon distribution in supragingival calculus from japanese monkeys (macaca fuscata). | using an electron-probe microanalyser, the distribution of silicon and other elements in supragingival dental calculus in domestic japanese monkeys (macaca fuscata) was studied. in two out of four monkeys kept in animals centres, a localized silicon distribution was found in both fracture and oral surfaces of the calculi. the silicon-rich area consisting of silicon alone resembled opal, but the areas containing silicon and other metal ions such as magnesium, aluminium, potassium and iron resembl ... | 1994 | 7945018 |
| chromosomal painting shows that "marked chromosomes" in lesser apes and old world monkeys are not homologous and evolved by convergence. | cytogeneticists have long held that the single pair of metacentric, nor-bearing "marked chromosomes" in lesser apes (hylobatidae) and old world monkeys (cercopithecidae) are homologous. hylobatids have sometimes been excluded from hominoidea (great apes and humans) and phylogenetically allied with the lower primates, primarily on the basis of this shared "trait." however, in situ hybridization of human chromosome-specific dna probes to chromosomes of hylobates lar, h. syndactylus, h. concolor, c ... | 1995 | 7956365 |
| serological features of infection with an epstein-barr-virus-like agent in japanese macaques (macaca fuscata). | | 1993 | 7959440 |
| neural activities in the fronto-opercular cortex of macaque monkeys during tasting and mastication. | we recorded responses from 298 units in the fronto-opercular cortex (fop) of three japanese macaque monkeys. the units were activated while animals were drinking or eating. three types of units could be defined: units with transient responses to the delivery of all the fluid into the mouth (on-type units; n = 123); units activated in association with certain oral movements, e.g., licking (mo-type units; n = 90); and units responsive specifically to a certain fluid (taste units; n = 85). in both ... | 1994 | 7967217 |
| the origin of human chromosome 2 analyzed by comparative chromosome mapping with a dna microlibrary. | fluorescence in situ hybridization (fish) of microlibraries established from distinct chromosome subregions can test the evolutionary conservation of chromosome bands as well as chromosomal rearrangements that occurred during primate evolution and will help to clarify phylogenetic relationships. we used a dna library established by microdissection and microcloning from the entire long arm of human chromosome 2 for fluorescence in situ hybridization and comparative mapping of the chromosomes of h ... | 1994 | 7981945 |
| ultrastructural evidence for innervation of the endothelium and interstitial cells in the atrioventricular valves of the japanese monkey. | a rich supply of nerves to the atrioventricular valve has been demonstrated. the role of the valvular nerves is still controversial because the target sites of the nerves have not been confirmed. | 1994 | 7992882 |
| responses to histamine and acetylcholine in isolated monkey mesenteric veins versus arteries. | the aim was to analyse and compare mechanisms of histamine or acetylcholine action in mesenteric venous and arterial strips obtained from japanese monkeys. | 1994 | 8025911 |
| responses to histamine and acetylcholine in isolated monkey mesenteric veins versus arteries. | the aim was to analyse and compare mechanisms of histamine or acetylcholine action in mesenteric venous and arterial strips obtained from japanese monkeys. | 1994 | 8025911 |
| direct projections from the ventral premotor cortex to the hindlimb region of the supplementary motor area in the macaque monkey. | a retrograde tracer, diamidino yellow, was injected into the hindlimb region of the supplementary motor area after intracortical microstimulation mapping in the japanese monkey. as a result, a cluster of retrogradely labeled neurons was found in the caudal bank of the arcuate sulcus, which corresponds to the ventral premotor cortex. the present findings suggest that there exists a hindlimb representation in the ventral premotor cortex. | 1994 | 8084480 |
| involvement of nmda and non-nmda receptors in motor task-related activity in the primary and secondary cortical motor areas of the monkey. | the involvement of the nmda and non-nmda receptors in the task-related neuronal activity of the primary motor cortex (mi), premotor cortex (pm), supplementary motor area (sma), and an area rostral to the sma (pre-sma) of two monkeys (macaca fuscata) was examined during performance of a trained motor task. the selective nmda antagonist d-2-amino-5-phosphonovaleric acid (apv) and the non-nmda antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (cnqx) were iontophoretically applied to motor task-relate ... | 1993 | 8104568 |
| genetic analysis and molecular phylogeny of simian t-cell lymphotropic virus type i: evidence for independent virus evolution in asia and africa. | type c retroviruses, designated simian t-cell lymphotropic virus type i (stlv-i), have been isolated from several genera of old world monkeys and apes, but not from new world monkeys and prosimians. to determine the genomic diversity and molecular evolution of stlv-i and to clarify their genetic relationship to human t-cell lymphotropic virus type i (htlv-i), we enzymatically amplified, then directly sequenced selected regions of the gag, pol, env, and px genes of stlv-i strains from asia and af ... | 1994 | 8116255 |
| [in vitro fertilization using japanese monkey (macaca fuscata) eggs and cynomolgus monkey (macaca fascicularis) frozen/thawed spermatozoa]. | using four female japanese monkeys, follicular growth was induced by multiple pmsg and single hcg injections, and oocytes were collected from their follicles. pmsg, 200 iu, was injected six or eight times to stimulate follicular growth, and in both cases growth of the follicles was adequately induced. forty-seven (50.0%) oocytes were recovered from 94 follicles of two of the females and transported from inuyama-shi to tsukuba-shi in 10 hours. five mature oocytes and 42 immature oocytes were obse ... | 1994 | 8119342 |
| [in vitro fertilization using japanese monkey (macaca fuscata) eggs and cynomolgus monkey (macaca fascicularis) frozen/thawed spermatozoa]. | using four female japanese monkeys, follicular growth was induced by multiple pmsg and single hcg injections, and oocytes were collected from their follicles. pmsg, 200 iu, was injected six or eight times to stimulate follicular growth, and in both cases growth of the follicles was adequately induced. forty-seven (50.0%) oocytes were recovered from 94 follicles of two of the females and transported from inuyama-shi to tsukuba-shi in 10 hours. five mature oocytes and 42 immature oocytes were obse ... | 1994 | 8119342 |
| heterogeneity of carbonic anhydrase and 68 kda neurofilament in nerve roots analyzed by two-dimensional electrophoresis. | the heterogeneity of carbonic anhydrase (ca) and 68 kda neurofilament (nf) in nerve roots of japanese monkeys (macaca macacus) was analyzed by two-dimensional electrophoresis combined with immunoblotting. ca was detected as heterogeneous spots of type i and ii having the same molecular weight (m(r)) but different isoelectric point (pi), in the range of ph 4.5-5.5. ca had much higher concentrations in soluble fractions of dorsal roots than ventral roots but not in membrane-bound fractions of eith ... | 1993 | 8125058 |
| heterogeneity of carbonic anhydrase and 68 kda neurofilament in nerve roots analyzed by two-dimensional electrophoresis. | the heterogeneity of carbonic anhydrase (ca) and 68 kda neurofilament (nf) in nerve roots of japanese monkeys (macaca macacus) was analyzed by two-dimensional electrophoresis combined with immunoblotting. ca was detected as heterogeneous spots of type i and ii having the same molecular weight (m(r)) but different isoelectric point (pi), in the range of ph 4.5-5.5. ca had much higher concentrations in soluble fractions of dorsal roots than ventral roots but not in membrane-bound fractions of eith ... | 1993 | 8125058 |
| lack of susceptibility of various primates and woodchucks to hepatitis c virus. | five different species of primates including cynomolgus monkey, rhesus monkey, green monkey, japanese monkey, and doguera baboon and woodchucks were inoculated intravenously with infectious serum from a chimpanzee infected with hepatitis c. serum samples obtained weekly from these animals were negative for hepatitis c virus rna and anti-hcv during six months following inoculation. furthermore, serum alanine aminotransferase remained within normal limits, and normal liver histology was seen. this ... | 1993 | 8169947 |
| [the effect of pta on cerebral vessels in experimental vasospasm: a histopathological study]. | although the percutaneous transluminal angioplasty (pta) is an useful procedure for the treatment of symptomatic vasospasm after subarachnoid hemorrhage, the morphological changes in spastic intracranial vessels after pta are not yet clear. the purpose of this study was to evaluate the effects of pta angiographically and histologically. chronic cerebral vasospasm was induced by producing a blood clot in the subarachnoid space around the top of internal carotid siphon in japanese monkey. after an ... | 1994 | 8190607 |
| anti-atherosclerotic and plasma lipid lowering effects of the novel calcium blocker with alpha 1-adrenoceptor antagonistic activity, monatepil, in high cholesterol diet-fed japanese macaca fuscata monkeys. | 1. the preventive effects of atherosclerosis and hyperlipidemia of monatepil ([(+-)-n-(6,11-dihydrodibenzo [b,e]thiepin-11-yl)-4-(4-fluorophenyl)-1-piperazine-butanamide+ + +]monomaleate , aj-2615, cas 103377-41-9), a new antihypertensive drug with potent calcium antagonistic and alpha 1-adrenoceptor blocking activities, were investigated in japanese monkeys (macaca fuscata) fed with a cholesterol-rich diet (2% cholesterol + 6% corn oil) and compared with those of prazosin. 2. the dose of monate ... | 1994 | 8192692 |
| anti-atherosclerotic and plasma lipid lowering effects of the novel calcium blocker with alpha 1-adrenoceptor antagonistic activity, monatepil, in high cholesterol diet-fed japanese macaca fuscata monkeys. | 1. the preventive effects of atherosclerosis and hyperlipidemia of monatepil ([(+-)-n-(6,11-dihydrodibenzo [b,e]thiepin-11-yl)-4-(4-fluorophenyl)-1-piperazine-butanamide+ + +]monomaleate , aj-2615, cas 103377-41-9), a new antihypertensive drug with potent calcium antagonistic and alpha 1-adrenoceptor blocking activities, were investigated in japanese monkeys (macaca fuscata) fed with a cholesterol-rich diet (2% cholesterol + 6% corn oil) and compared with those of prazosin. 2. the dose of monate ... | 1994 | 8192692 |
| differential effects of muscimol microinjection into dorsal and ventral aspects of the premotor cortex of monkeys. | 1. a gamma aminobutyric acid (gabaa) receptor agonist, muscimol (sigma, 5 micrograms/microliters solution), and a gabab receptor agonist and antagonist, baclofen and phaclofen, respectively, were injected (1.0 microliter) into the dorsal and ventral aspects of the premotor cortex (pm) of two japanese monkeys (macaca fuscata), while they were performing a motor task that required wrist flexion or extension to a target. the correct movement was instructed by either 1) a conditional color cue [gree ... | 1994 | 8201409 |
| differential effects of muscimol microinjection into dorsal and ventral aspects of the premotor cortex of monkeys. | 1. a gamma aminobutyric acid (gabaa) receptor agonist, muscimol (sigma, 5 micrograms/microliters solution), and a gabab receptor agonist and antagonist, baclofen and phaclofen, respectively, were injected (1.0 microliter) into the dorsal and ventral aspects of the premotor cortex (pm) of two japanese monkeys (macaca fuscata), while they were performing a motor task that required wrist flexion or extension to a target. the correct movement was instructed by either 1) a conditional color cue [gree ... | 1994 | 8201409 |
| monkey cerebral arterial relaxation caused by hypercapnic acidosis and hypertonic bicarbonate. | in helical strips of japanese monkey cerebral arteries contracted with vasoconstrictors, applications of high co2 (15% compared with 5% co2 in control media) and hypertonic nahco3 (50 mm) produced relaxations. similar relaxations were also obtained in human cerebral arterial strips. hypercapnia increased pco2 and resulted in acidosis in the bathing media, and the addition of nahco3 restored the ph to normal with high pco2 and increased the osmotic pressure. the relaxant responses were not influe ... | 1993 | 8214129 |
| middle-latency responses of awake and anesthetized japanese macaques. | the middle-latency response (mlr) of two japanese macaques were investigated. in the awake state, the configuration of the mlr components showed two positive peaks: pa and pb. the latency and the configuration of pa were very similar to those of humans. in the topographic recordings, the largest pa amplitude was found from the vertex, or r1, which is 1 cm lateral to the vertex. in the anesthetic state, pa and pb gradually disappeared. this study shows that the mlr in awake japanese macaques is s ... | 1993 | 8216029 |
| quantitative analysis of species identification tests of bloodstains using anti-human serum. | immunological reactions of bloodstains of human and animals to anti-human serum were analysed quantitatively to determine which technique is the most effective to differentiate human bloodstains from those of animals. the lower threshold of counter-electrophoresis was 10-25 micrograms protein/ml and increased only slightly with increasing age of the bloodstains, while that of the ring test and immunodiffusion decreased greatly. in counter-electrophoresis, absorption of anti-human serum by japane ... | 1993 | 8247107 |
| role of macrophage tissue factor in the development of the delayed hypersensitivity reaction in monkey skin. | delayed-type hypersensitivity (dth) reaction is a cell-mediated immune response, characterized by fibrin deposition. to determine whether macrophage tissue factor (tf), an initiator of blood coagulation, was associated with the dth reaction, tf expression on macrophages and resulting fibrin deposition at the site of dth, induced in bacille-calmette-guerin (bcg)-sensitized japanese monkeys with intradermal administration of pure protein derivative of tuberculin (ppd), were examined immunohistoche ... | 1993 | 8258156 |
| role of macrophage tissue factor in the development of the delayed hypersensitivity reaction in monkey skin. | delayed-type hypersensitivity (dth) reaction is a cell-mediated immune response, characterized by fibrin deposition. to determine whether macrophage tissue factor (tf), an initiator of blood coagulation, was associated with the dth reaction, tf expression on macrophages and resulting fibrin deposition at the site of dth, induced in bacille-calmette-guerin (bcg)-sensitized japanese monkeys with intradermal administration of pure protein derivative of tuberculin (ppd), were examined immunohistoche ... | 1993 | 8258156 |
| vocalizations of rhesus (macaca mulatta) and japanese (m. fuscata) macaques cross-fostered between species show evidence of only limited modification. | two rhesus and two japanese macaque infants were cross-fostered between species in order to study the effects of auditory experience on vocal development. both the cross-fostered and normally raised control subjects were observed over the first 2 years of life and their vocalizations were tape-recorded. we classified 8053 calls by ear, placed each call in one of six acoustic categories, and calculated the rates at which different call-types were used in different social contexts. species differe ... | 1993 | 8270122 |
| distribution of pacinian corpuscles in the hand of the monkey, macaca fuscata. | the size and distribution of pacinian corpuscles were investigated in the palmar aspect of both hands of the monkey, macaca fuscata. most pacinian corpuscles were located in the dermis (dermal type) and subcutaneous tissue (subcutaneous type) throughout the hand. on light microscopy there were no differences in the structure of these 2 types, although almost all the subcutaneous type had a greater longitudinal dimension than the dermal type. corpuscles were oval or elliptical and their longitudi ... | 1993 | 8270469 |
| kri-1314: an orally effective inhibitor of human renin. | biochemical and pharmacological properties of kri-1314, a newly synthesized, low molecular weight (m.w.: 690) renin inhibitor, were investigated in vitro and in vivo. the novel amino acid norstatine, which is shorter in chain length than the well-known statine, was incorporated into kri-1314 as a tetrahedral transition-state analogue for the leu10-val11 scissile peptide in the renin substrate. kri-1314 more strongly inhibited plasma renins from primates than those from dogs, rabbits, guinea pigs ... | 1993 | 8271523 |
| kri-1314: an orally effective inhibitor of human renin. | biochemical and pharmacological properties of kri-1314, a newly synthesized, low molecular weight (m.w.: 690) renin inhibitor, were investigated in vitro and in vivo. the novel amino acid norstatine, which is shorter in chain length than the well-known statine, was incorporated into kri-1314 as a tetrahedral transition-state analogue for the leu10-val11 scissile peptide in the renin substrate. kri-1314 more strongly inhibited plasma renins from primates than those from dogs, rabbits, guinea pigs ... | 1993 | 8271523 |