| is dna methylation responsible for mammalian x chromosome inactivation? | mohandas et al. (1981) have proposed that mammalian x chromosome inactivation involves segmental methylation of cytosine residues in the dna at multiple sites along the x chromosome. using antibodies specific for 5-methylcytosine, we have found no detectable difference in the extent of methylation of the dna in the two x chromosomes of owl monkey or human females. thus inactivation (facultative heterochromatization) of the x chromosome is not due to, or associated with, intense dna methylation c ... | 1982 | 6756802 |
| patterns of connections from the striate cortex to cortical visual areas in superior temporal sulcus of macaque and middle temporal gyrus of owl monkey. | double label-emulsion autoradiography has been used in rhesus monkeys to study cortico-cortical connections, arising from two separate sites of the striate cortex, and going in the same hemisphere into the cortex in the medial part of the posterior (or ventral) bank of the superior temporal sulcus (area sts). the projections from a single cortical locus are segregated into several patches of labeled terminals in layers iii-iv, which form bands in consecutive sections. fields of distribution of t ... | 1980 | 6766146 |
| aqueous humor changes after experimental filtering surgery. | we studied aqueous humor of rhesus and owl monkeys for its effect on the growth of subconjunctival fibroblasts in tissue culture. aqueous humor samples obtained before glaucoma surgery inhibited the initiation of growth of fibroblasts. however, postoperative aqueous humor samples supported growth of fibroblasts. the change in aqueous humor physiology lasted for up to two months after glaucoma surgery. our study indicated that possibly material added to the postoperative aqueous humor inactivates ... | 1980 | 6766671 |
| a preliminary assessment of na-hyaluronate injection into "no man's land" for primary flexor tendon repair. | a special fraction of na-hyaluronate (healon) was used for enhancement of repair of flexor tendon lacerations in "no man's land" to assess its role in preventing adhesion formation. the profundus tendons of the third and fourth fingers in owl monkeys were lacerated and repaired, and the superficialis tendons were resected. prior to closure, saline solution or healon paste was applied around the tendon. the fingers were immobilized for 4-5 weeks with the proximal interphalangeal joint (pip) at 90 ... | 1980 | 6768485 |
| the chesson strain of plasmodium vivax in aotus monkeys and anopheline mosquitoes. | the chesson strain of plasmodium vivax was studied in aotus trivirgatus monkeys. parasitemia in intact and splenectomized animals was similar to that reported for this strain in man. comparative infectivity studies with mosquitoes fed on infected monkeys indicated that the most susceptible was anopheles freeborni, followed by an. balabacensis, an. culicifacies, an. maculatus, an. atroparvus, an. stephensi, an. quadrimaculatus, and an. albimanus. transmissions via sporozoites from an. maculatus w ... | 1980 | 6771379 |
| a comparative study of rosette formation in 12 species of nonhuman primates. | lymphocytes, isolated from the peripheral blood of 12 species of nonhuman primates, were tested for the ability to form rosettes with antibody-complement-coated erythrocytes (eac rosettes) and with erythrocytes from various animal species. in general, new world primates (wooly, spider colobus, capuchin and owl monkeys) had a greater number of eac rosette-forming cells (30-44%) than did old world monkeys (baboons, gibbons, rhesus, cynomolgus, pigtailed, stumptailed and japanese macaques) (22-30 ... | 1980 | 6771405 |
| differentiating owl monkey t and b lymphocytes by rosette formation. | subpopulations of aotus trivirgatus lymphocytes can be differentiated by the technique of rosette formation. owl monkey b cells can be identified by erythrocyte-antibody-complement (eac) rosette formation, since over 90% of eac rosette-forming cells (rfc) have detectable surface immunoglobulins. a separate population of aotus lymphocytes forms rosettes directly with sheep erythrocytes (e rosettes) and appears to be thymus-dependent (t cells) because (1) e rosette formation is blocked by anti-thy ... | 1980 | 6771407 |
| evaluation of three strains of influenza a virus in humans and in owl, cebus, and squirrel monkeys. | the virulence of three cloned influenza a viruses was compared in humans and in three readily available species of nonhuman primates (owl, squirrel, and cebus monkeys) in an attempt to identify a species of monkey that could be used to investigate the genetic basis of attenuation of influenza a viruses for humans. three influenza a viruses from two subtypes, i.e., the a/udorn/72 (h3n2), a/alaska/77 (h3h2), and a/hong kong/77 (h1h1) viruses, produced febrile influenzal illness in humans. squirrel ... | 1980 | 6772565 |
| therapeutic efficacy of vitamin e and selenium in treating hemolytic anemia of owl monkeys (aotus trivirgatus). | the roles played by vitamin e and by selenium in the anemia of owl monkeys were studied by injecting a mixture of the two antioxidants in 17 anemic monkeys. the result was an increase in mean hemoglobin concentration from 8.6 +/- 2.2 to 11.9 +/- 2.5 g/dl; in 1o of these monkeys with typically elevated numbers of circulating nucleated erythrocytes, the mean number of such cells per 10(2) leukocytes declined from 50.1 +/- 49.9 to 0.6 +/- 1.2. injections of vitamin e alone in eight monkeys were les ... | 1980 | 6772878 |
| species-specific homogeneity of the primate alu family of repeated dna sequences. | we have determined the base sequence of several cloned alu family members from the dnas of a new world monkey (owl monkey) and a prosimian (galago). the three owl monkey alu family members reported here belong to a single 300 base pair consensus sequence which closely resembles the human alu family consensus. the galago alu family members can best be represented as belonging to either of two related but distinct consensus sequences. one of the two galago alu family subgroups (type i) more accura ... | 1983 | 6647031 |
| hemolytic complement measurement in eleven species of nonhuman primates. | a microtiter system was used to measure hemolytic complement levels in serum from eleven nonhuman primate species. the species studied were macaca mulatta (rhesus macaque), macaca radiata (bonnet macaque), macaca nemestrina (pig-tailed macaque), macaca fascicularis (crab-eating macaque), macaca speciosa (stumptailed macaque), papio cynocephalus (yellow baboon), papio anubis (olive baboon), cercopithecus aethiops (african green monkey), aotus trivirgatus (owl monkey), ateles fusceps robustus (spi ... | 1983 | 6659335 |
| plasmodium falciparum gametocytes from culture in vitro develop to sporozoites that are infectious to primates. | gametocytes of two strains of the human malaria parasite plasmodium falciparum have been produced in high density by means of a continuous-flow cultivation system. the gametocytes of these two strains infected a mean of 36 percent and 71 percent, respectively, of anopheles freeborni mosquitoes that fed on a suspension of red blood cells containing the culture gametocytes. sporozoites harvested from the infected mosquito salivary glands were infective to the chimpanzee (pan troglodytes) and the o ... | 1982 | 7051285 |
| modification of corneal curvature following radial keratotomy in primates. | radial keratotomy was performed on six stumptail monkey eyes (macaca speciosa) and 22 owl monkey eyes (aotus trivirgotus). changes in keratometry, specular microscopy, and tonometry have been studied postoperatively for three to six months. sixteen radial incisions in stumptail monkey eyes resulted in a significant mean corneal flattening of 2.75 diopters (p less than 0.005). this effect was stable with a mean 2.50 diopters flattening remaining six months after surgery. sixteen radial incisions ... | 1981 | 6798518 |
| reactivity of monoclonal antibodies against human leucocyte antigens with lymphocytes of non-human primate origin. | the phylogenetic distribution of antigens present on human lymphocytes was investigated by incubating human or simian cells with murine anti-human monoclonal antibodies and then determining the level of reactivity with a radiolabelled anti-murine igg reagent. the monoclonal antibodies used were specific for a t-cell antigen, lymphoid and lymphoid:myeloid antigens, ia antigens, and beta 2 microglobulin. the cells examined included b- and t-lymphoblastoid cell lines and fresh peripheral blood lymp ... | 1981 | 6801142 |
| the myoglobin of primates: the night monkey, aotes trivirgatus (cebidae, platyrrhini, anthropoidea). | the amino acid sequence of the myoglobin of the south american night monkey, aotes trivirgatus, is identical to that of the marmoset (callithrix jacchus [1]) except for residue 21 which is isoleucine in the marmoset, like in all other anthropoids, but valine in aotes. analysis of a possible pathway of the evolution of aotes myoglobin using 18 known primate myoglobin sequences [2-5] supports the classification of the night monkey within anthropoidea and platyrrhini but it indicates that this spec ... | 1984 | 6692912 |
| species variations in the pathophysiologic responses of vertebrate eyes to a chemical irritant, nitrogen mustard. | much of our knowledge of the ocular responses to irritants is derived from studies on the effects of mustards applied topically to the rabbit eye. the present study shows, however, that vertebrate eyes display profound species variations in the initial (first 6 hours) response to nitrogen mustard (nm). rabbits and guinea pigs showed two episodes, ducks and cats one, and owl monkeys no episode of increased intraocular pressure. development of anterior chamber flare and cellular invasion was seen ... | 1983 | 6826323 |
| gene map of the new world bolivian owl monkey, aotus. | somatic cell hybrids between rodent cells and owl monkey cells preferentially segregating primate chromosomes were selected for mapping owl monkey genes. concordant segregation of phenotype and chromosome in 35 independent hybrid clones and 105 subclones with different reduced owl monkey complements provided evidence for the assignment of 17 gene loci to 9 chromosomes of the bolivian owl monkey with a karyotype vi (2n = 49 male, 50 female). the assignments include: mdh1 to chromosome 2, mdh2 to ... | 1983 | 6827067 |
| nerve fiber layer of the owl monkey retina: retinotopic organization. | the organization of nerve fiber bundles, stained by microelectrode injection of horseradish peroxidase, was examined in the retina of the owl monkey. fibers were traced across the retina in whole mounts and serial sections to evaluate their retinotopic order. long nasal fibers showed little tendency to wander among bundles but were distributed randomly within the bundles near the disc. long arcuate and papillomascular fibers, in sharp contrast, spread laterally among many bundles as they approac ... | 1983 | 6832902 |
| experimental infection of the new world owl monkey (aotus trivirgatus) with hepatitis a virus. | epidemiological studies have demonstrated the susceptibility of the owl monkey (aotus trivirgatus) to hepatitis a virus, but have not shown an association between infection and histopathological or chemical evidence of liver disease. therefore, 12 seronegative, colony-bred monkeys were inoculated intravenously with a fecal suspension containing either pa33 strain hepatitis a virus (a strain recovered from a naturally infected aotus sp.) or hm-175 virus (recovered from a human). viral antigen was ... | 1983 | 6840861 |
| comparative gene mapping of the owl monkey, aotus, with karyotypes v (2n = 46) and vi (2n = 49, 50). | biochemical analysis of cytogenetically defined rodent--owl monkey hybrid cell lines segregating owl monkey chromosomes allowed the assignment of 14 structural gene markers to seven owl monkey karyotype v (k-v, 2n = 46) chromosomes. comparative study of assigned gene loci to chromosomes of owl monkey karyotype v (k-v, 2n = 46) and karyotype vi (k-vi, 2n = 49/50) provides the first evidence supporting some of the previously proposed mechanics of chromosomal rearrangements responsible for the grea ... | 1983 | 6851668 |
| automatic watering device for owl monkeys. | | 1983 | 6855192 |
| time and location analysis of lesion formation in photocoagulation. | fourteen eyes from seven owl monkeys were used for study of the time and location within the retinal layers of the formation of the white reactions produced by photocoagulation with green (530.9 nm), yellow (568.2 nm), or red (647.1 nm) krypton wavelengths. locations on the retina with equivalent conditions of absorbance were chosen. the white reaction formed in the first 100 ms of application. the depth at which the most damage occurred depended on the wavelength used. the final shape of the le ... | 1983 | 6860213 |
| representations of the body surface in areas 3b and 1 of postcentral parietal cortex of cebus monkeys. | the somatotopic organization of postcentral parietal cortex was determined with microelectrode mapping methods in a new world monkey, cebus albifrons. as in previous studies in macaque, squirrel and owl monkeys, two separate representations of the body surface were found in regions corresponding to the architectonic fields 3b and 1. the two representations were roughly mirror-images of each other, with receptive field locations matched for recording sites along the common border. as in other mon ... | 1983 | 6860957 |
| functional properties of neurons in middle temporal visual area of the macaque monkey. i. selectivity for stimulus direction, speed, and orientation. | 1. recordings were made from single units in the middle temporal visual area (mt) of anesthetized, paralyzed macaque monkeys. a computer-driven stimulator was used to make quantitative tests of selectivity for stimulus direction, speed, and orientation. the data were taken from 168 units that were histologically identified as being in mt. 2. the results confirm previous reports of a high degree of direction selectivity in mt. the response above background to stimuli moving in a unit's preferred ... | 1983 | 6864242 |
| cell-mediated immune response to respiratory syncytial virus infection in owl monkeys. | the suitability of owl monkeys as experimental models to study the cellular immune response to respiratory syncytial virus (rsv) infection was examined. seronegative owl monkeys inoculated intranasally with rsv shed large quantities of virus and developed clinically evident upper respiratory disease. rsv infected monkeys had significant lymphoproliferative responses to rsv antigen by 4 weeks post-infection. in contrast, no positive blastogenic responses were elicited during the acute phase of il ... | 1983 | 6883807 |
| evidence for methylation of inactive human rrna genes in amplified regions. | in two unrelated families, the short arm of a 14p+ marker chromosome contains an increased number of copies of the 18s + 28s rrna genes without a comparable increase in the transcriptional activity, as shown by silver staining. the dna in this region is highly enriched in 5-methylcytosine, as shown by specific antibody binding. in contrast, the owl monkey and cat have a single major nucleolus organizer region (nor) per haploid genome; these nors contain about the same number of rrna genes as the ... | 1981 | 6940826 |
| reduction of intraocular pressure in normal and glaucomatous primate (aotus trivirgatus) eyes by topically applied prostaglandin f2 alpha. | topical application of a single dose of 1.0 mg prostaglandin f2 alpha (pgf2 alpha) onto the cornea of five trained owl monkeys (aotus trivirgatus) caused a prolonged and highly significant ocular hypotony. the intraocular pressure (iop) of the treated eye was 4.7 +/- 0.9 mm hg below that of the control eye 18 to 24 hr after pgf2 alpha application and remained significantly reduced for over 72 hr. miosis, aqueous flare, and accumulation of cells in the anterior chamber were minimal in extent. the ... | 1981 | 6949676 |
| chromosome localization and gene synteny of the major histocompatibility complex in the owl monkey, aotus. | rodent cells were hybridized with owl monkey (aotus) cells of karyotypes ii, iii, v, and vi. aotus-rodent somatic hybrid lines preferentially segregating aotus chromosomes were selected to determine the chromosomal location of the major histocompatibility complex and other genes with which it is synthetic in man. based on correlation between concordant segregation of the chromosome as visualized by g-banding and expression of the aotus antigens or enzymes in independent aotus-rodent hybrid clone ... | 1982 | 6953044 |
| the effect of t cell growth factor on the cell cycle of primate t cells. | the effect of t cell growth factor (tcgf) on the cell cycle of four t cell lines that differed in their response to tcgf was studied. activated normal marmoset t cells (oh-1) were totally dependent on the addition of tcgf for long-term proliferation. in the absence of tcgf, the cells were incapable of traversing the cell cycle and became arrested in g1. the addition of tcgf to arrested oh-1 cells stimulated them to enter the s phase after a lag phase of 24 to 33 hr. the tcgf-stimulated cells rea ... | 1982 | 6981667 |
| purification and properties of a factor from leukaemic t cells which non-specifically enhances the antibody response. | a non-specific immunoenhancing factor from leukemia owl monkey peripheral t lymphocytes has been purified and partially characterized. owl monkey enhancing factor, omef, is a glycoprotein with a molecular weight of 39,000 and an isoelectric point of ph 6.5. it acts at nanogram levels on day 2 of the in vitro immune response to enhance the number of plaque-forming cells produced to sheep red blood cells in a murine assay system but has no effect when added on day 0 to this system but has no effec ... | 1981 | 7007219 |
| the conversion of an enhancing factor to a suppressor factor by the formation of an aggregate molecule. | a non-specific suppressor factor, owl monkey suppressor factor, omsf, from leukaemic owl monkey peripheral t lymphocytes has been isolated and characterized. omsf is a glycoprotein of a molecular weight of 66,000 which can be produced from purified owl monkey enhancing factor, omef, by both tris buffer dialysis and by repeated freezing and thawing. sds gel electrophoresis demonstrates that omsf is composed of 39,000 mol. wt subunits which co-migrate with the omef molecule. this suppressor acts a ... | 1981 | 7007220 |
| studies on the west pakistan strain of plasmodium vivax in aotus monkeys and anopheline mosquitoes. | the west pakistan strain of plasmodium vivax was established in 17 aotus trivirgatus griseimembra monkeys. parasitemias were moderate. prior experience of the animals with p. falciparum and a heterologous strain of p. vivax resulted in a marked reduction in parasitemias, but maintenance of mosquito infectivity similar to that of animals with no prior malaria. comparative infectivity studies indicated that this strain in aotus monkeys was most infective to anopheles freeborni mosquitoes followed ... | 1980 | 7007600 |
| adaptation of a nigerian strain of plasmodium falciparum to panamanian aotus trivirgatus. | a patent infection (more than 190 days duration) with plasmodium falciparum, obtained directly from a patient who had been exposed to malaria in nigeria, was established in a splenectomized panamanian owl monkey, aotus trivirgatus griseimembra. subinoculations from the original monkey recipient into one splenectomized and two normal a. t. griseimembra produced primary patient parasitemias of 18-54 days duration. these results represent the first successful adaptation of p. falciparum from man to ... | 1981 | 7011068 |
| electrophoretic patterns of aminoacylase-1 (acy-1) isozymes in vertebrate cells and histochemical procedure for detecting acy-1 activity. | a histochemical procedure has been developed for staining aminoacylase-1 (acy-1) isozymes after electrophoresis on cellulose acetate membranes. n-formyl-l-methionine and n-acetyl-l-methionine were excellent enzyme substrates in the staining reaction. the acy-1 isozymes from tissue culture cells of several vertebrate species showed distinguishable electrophoretic patterns. the acy-1 isozymes in extracts of mouse, human, owl monkey, and african green monkey kidney cells each had electrophoretic mo ... | 1980 | 6781469 |
| hybrid production in owl monkeys (aotus trivirgatus). | a colony of owl monkeys was established with 63 breeding pairs, paired according to matching karyotypes. 3 pairs were formed as a result of limited space, even though karyotypes were considered incompatible. 2 of these pairs produced offspring. | 1982 | 7062716 |
| hemolytic anemia of owl monkeys: red blood cell lipid alterations. | | 1982 | 7063507 |
| retinal irradiance from vitrectomy endoilluminators. | we compared the maximum light output of selected 19- and 20-gauge continuous-fiber and detachable-tip endoilluminators to the retinal damage threshold for intravitreal fiber-optic light in the owl monkey. because of cumulative light toxicity to the retina there is a substantial risk of retinal damage from endoillumination when the endoilluminator is close to the retina (for example, during membrane peeling procedures) and especially when the continuous-fiber endoilluminator with high light outpu ... | 1982 | 7091278 |
| erythrocyte glyoxalase i polymorphism in the owl monkey, aotus. | three erythrocyte glyoxalase i phenotypes were observed in a sample of 235 karyotypically defined new world owl monkeys, aotus. the selective distribution of glyoxalase i allele (glo1, glo2) is related to the karyotype of each animal. owl monkeys with a karyotype vi had an equal distribution of glo1 and glo2 genes in the population. aotus with karyotype ii, iii, iv, or v had, exclusively, the glo2 allele (expressed as the fast electrophoretic phenotype), in contrast with monkeys with karyotype i ... | 1982 | 7092802 |
| erythrocyte characteristics in vitamin e-responsive anemia of the owl monkey (aotus trivirgatus). | to characterize the vitamin e-responsive anemia occurring in owl monkeys (aotus trivirgatus), osmotic fragility, and h2o2-induced and time-dependent hemolysis, as well as rbc lipid peroxidation, were compared in anemic and nonanemic owl monkeys. whereas vitamin e serves as a lipid-soluble antioxidant, the glutathione peroxidase system functions in the water-soluble phase of the cell. thus, activity of glutathione peroxidase, glutathione reductase, and glucose-6-phosphate dehydrogenase, as well a ... | 1982 | 7103234 |
| comparison of behaviour between 2 subspecies of owl monkey (aotus trivirgatus) in a laboratory environment. | to evaluate potential factors affecting reproductive performance, 6 monkeys of colombian and 6 of bolivian origin, housed as mated pairs, were observed via closed circuit television and a remote-controlled camera. behavioural differences in feeding and drinking, locomotor activity, environmental interaction, positive social interaction, autogrooming, nestbox occupancy, and playing were observed. the differences noted indicate that the subspecies may have different social structures. | 1982 | 7109532 |
| toxicity of intravitreous miconazole. | miconazole nitrate is a broad-spectrum antimycotic agent with low systemic and ocular toxicity. since this drug does not adequately penetrate the vitreous cavity by topical, subconjunctival, or intravenous routes, we determined whether it can be given intravitreously for fungal endophthalmitis. retinal and lens toxicity studies were carried out in 40 rabbits and three owl monkeys. results showed that both miconazole and its vehicle produced toxic damage to the retina and crystalline lens in conc ... | 1982 | 7115181 |
| studies of herpes virus latency in the sensory spinal ganglia of rabbits. | experimental latent herpes infection of rabbit dorsal root ganglia (drg) is reported. the simian herpes virus used was derived from fatal natural infection in owl monkeys and has limited neurotropism in the rabbit. following intradermal injection of the flank it causes a local lesion followed only by dorsal root ganglionitis; segmental paraesthesia and/or sensory loss going on to clinical recovery. methods were developed for mapping sensory losses. virus could be immediately re-isolated from ski ... | 1982 | 7153508 |
| outer retina ischemic infarction--a newly recognized complication of cataract extraction and closed vitrectomy. part 2. an animal model. | intraocular pressure was artificially elevated above systolic blood pressure in 40 owl monkey eyes. diffuse retinal whitening of the posterior pole and subsequent retinal pigment epithelial disruption were produced in nine of ten eyes with high pressure for 90 minutes or longer, but also in a few eyes with high pressure for a shorter duration. fluorescein angiography and histologic examination demonstrated damage of the photoreceptors and retinal pigment epithelium with sparing of the inner reti ... | 1982 | 7162791 |
| a vaccine against human malaria--an utopia? | at the beginning of the 1980s, the future of the malaria vaccines looks bright; in recent years a number of basic problems have been solved. among the major landmarks have been the discovery of a suitable animal model for human malaria infections; the technique of culturing plasmodium falciparum; the findings that sporozoites, merozoites and gametocytes, or possibly antigens characterized with the hybridoma technique, can be used as vaccine antigens at least in animals; and that excellent protec ... | 1982 | 7171233 |
| cortical connections of striate cortex in the owl monkey. | injections of tritiated proline and horseradish peroxidase were used to study cortical connections of striate cortex in owl monkeys. all cases resulted in label in area 18 (v-ii) and the middle temporal visual area (mt). in most, but not all cases, label was also present in the dorsomedial visual area (dm). the connections between striate cortex and each of these three visual areas were retinotopic and reciprocal. projections to v-ii, mt, and dm were concentrated in layers iv and iii, while pyra ... | 1982 | 7174888 |
| retinal vessel photocoagulation: a quantitative comparison of argon and krypton laser. | retinal arteries of owl monkeys were photocoagulated with single exposures to argon laser green light (514 nm), krypton laser green light (531 nm), and krypton laser yellow light (568 nm). the distribution of damage along the vessel in different retinal layers was characterized geometrically after serial sectioning of the histopathologic material. krypton laser radiation (green and, to an even greater extent, yellow) produced measurably greater effects on retinal vessels and adjacent structures ... | 1981 | 7193661 |
| diurnal variations in plasma testosterone in a male nocturnal primate, the owl monkey (aotus trivirgatus). | six adult male owl monkeys were kept in conditions of controlled lighting (12 h white light alternating with 12 h of very dim reg light) and blood samples were taken at different times of day, once a week, for 10 weeks. plasma testosterone levels correlated with phases of the lighting cycle: highest levels (mean +/- s.e.m.) occurred in the light (24.8 +/- 5.3 ng/ml) and lowest levels during periods of darkness (4.7 +/- 1.2 ng/ml). the owl monkey is nocturnal, and these daily changes in circulati ... | 1981 | 7194914 |
| distribution of acetylcholinesterase in the geniculo striate system of galago senegalensis and aotus trivirgatus: evidence for the origin of the reaction product in the lateral geniculate body. | this inquiry began with the discovery that just two layers of the lateral geniculate nucleus (gl) of galago contain large amounts of acetylcholinesterase (ache). these two layers (layers 3 and 6) are similar in cell size and nissl-staining characteristics and project to the same layer in the striate cortex. to find out whether the pattern of staining is unique in the galago, we examined the distribution of ache in the lateral geniculate nucleus of the owl monkey, aotus trivirgatus. in this speci ... | 1980 | 7204639 |
| [follow-up study of macular function after retinal detachment surgery (author's transl)]. | forty patients successfully operated on for retinal detachment involving the macula were followed up for periods ranging from six months to nine years. the follow-up examination included testing for visual acuity, color perception and metamorphopsias, as well as biomicroscopy and fluorescein angiography. postoperative visual acuity was correlated with the preoperative duration of retinal detachment. as expected, visual outcome was reduced in cases with lesions demonstrated by biomicroscopy and/o ... | 1980 | 7206559 |
| the excretion of urinary steroids by the owl monkey (aotus trivirgatus) studied using open tubular capillary column gas chromatography and mass spectrometry. | | 1981 | 7206697 |
| thermoregulation in the only nocturnal simian: the night monkey aotus trivirgatus. | the night monkey, a tropical monkey, is the only nocturnal simian; its thermoregulation was studied for comparison with other nocturnal or diurnal primates and other tropical mammals. resting metabolic rate was 2.6 w (closed-circuit method) and 2.8 w (open-circuit method), 24 and 18% below the value predicted from body mass. the thermoneutral zone was very narrow; the lower critical temperature (lct) was 28 degrees c and the upper critical temperature (uct) was 30 degrees c. the body temperature ... | 1981 | 7212087 |
| susceptibility of aotus trivirgatus to leishmania braziliensis and l. mexicana. | two aotus trivirgatus (owl monkeys) were infected experimentally with leishmania braziliensis and two with l. mexicana strains of panamanian origin in a pilot study to determine the susceptibility and the course of infection of cutaneous leishmaniasis in this primate species. montenegro skin tests performed on all animals prior to parasite inoculation were negative. a standardized inoculum of promastigotes was injected intradermally on the nose of each monkey. all of the animals developed infect ... | 1981 | 7212172 |
| courses of infections with plasmodium falciparum in own monkeys displaying a microfilaremia. | infections with the uganda palo alto, malayan camp-ch/q, vietnam oak knoll, and vietnam smith strains of plasmodium falciparum in owl monkeys (aotus trivirgatus griseimembra) with concomitant microfilaremias usually, but not always, followed a more benign course than infections with the same strains in monkeys free of filarial infections. four distinct microfilariae were identified in systematic examinations of 26 monkeys, 5 with self-limited infections with p. falciparum, 9 with normally benign ... | 1981 | 7011072 |
| inhibition of in vitro growth of plasmodium falciparum by immune serum from monkeys. | three owl monkeys that had been immunized against the camp strain of plasmodium falciparum by infection were treated with chloroquine and rechallenged with parasites. immune serum caused a dose-dependent, time-dependent inhibition of in vitro parasite growth. heat-inactivation eliminated nonspecific inhibition by normal monkey serum without diminishing immune inhibition. purified igg from immune serum inhibited parasite growth. serum taken immediately before the second challenge did not inhibit ... | 1981 | 7024432 |
| the vitreous of the baby owl monkey. a model for rapid and complete gel-liquefaction. | the vitreous body of the baby owl monkey (aotus trivirgatus) exists as a highly elastic gel composed of a collagen-like network. the owl monkey vitreous liquefies completely within the first 2 years of the aotus life, corresponding to a human age of 8-10 years. thus, aotus provides the only known primate model for the rapid and complete liquefaction of the vitreous gel at an early age, the understanding of which may be of future relevance for clinical induction of therapeutic vitreous liquefacti ... | 1981 | 7262389 |
| leishmania donovani in the owl monkey (aotus trivirgatus) | | 1981 | 7268842 |
| comparison of the hypotensive and other ocular effects of prostaglandins e2 and f2 alpha on cat and rhesus monkey eyes. | it is generally accepted that exogenous or endogenous prostaglandins (pgs) can give rise to acute increases in intraocular pressure (iop) and to the development of flare and other signs of uveitis. it was recently shown, however, that low doses of pge2 and/or pgf2 alpha topically applied to rabbit or owl monkey eyes significantly reduce iop. the present experiments show that topical application of 10 to 500 micrograms of pge2 also causes a highly significant iop reduction in cat eyes lasting up ... | 1982 | 7076404 |
| radial keratotomy in non-human primate eyes. | we performed a prospective study of the effects of radial keratotomy in the owl monkey. we compared a 16-incision and an eight-incision radial keratotomy, and followed the changes in corneal curvature, corneal thickness, endothelial cell counts, and intraocular pressure. we compared the results of the changes in these clinical factors with a histopathologic and ultrastructural analysis of the time-related changes after radial keratotomy in another group of animals. we found that the loss of init ... | 1981 | 7270627 |
| zeitgeber-schedule dependent resynchronization of circadian rhythms in nocturnal mammals (primates and chiroptera). | changing the l:d time ratio of an entraining light-dark regime leads to characteristic alterations of the resynchronization behaviour of the circadian activity rhythms in night monkeys (aotus trivirgatus) and african fruit bats (rousettus aegyptiacus) after 8 h advance and delay shifts of the ld-zeitgeber. reduced speed of re-entrainment and occurrence of antidromic resynchronization point to a lower zeitgeber strength of 24-h ld-cycles with a prolonged d-phase. | 1981 | 7297663 |
| measles virus antibodies in a laboratory colony of owl monkeys (aotus trivirgatus). | serologic testing revealed that 17/84 (20.2%) of bought-in aotus and 1/31 (3.2%) of colony-born aotus had haemagglutination-inhibition antibody. clinically-inapparent measles infections were detected in 3 monkeys by increased antibody titres. following the detection of a recent infection, antibody titre persisted at a high level for at least 240 days. although 84% of the monkeys were sero-susceptible, no further serological evidence of measles infection occurred. | 1981 | 7341843 |
| a retrospective study of etiological factors of abortion in the owl monkey, aotus trivirgatus. | abortions in owl monkeys occurred in the late second and early third trimesters. retrospective study of clinical records showed that handling, maternal anemia, karyotype, and season were unassociated with abortion. most aborted infants had no gross lesions at necropsy. some had renal tubular necorsis, probably a postmortem change. | 1981 | 7343667 |
| nephritis and hemolytic anemia in owl monkeys (aotus trivirgatus). | the two most common diseases of captive owl monkeys (aotus trivirgatus) are hemolytic anemia and glomerulonephritis. the anemia is characterized by total red blood cell counts between 0.45 and 3.44 x 10(6) microliters, hemoglobin values as low as 1.0 g/dl, and many circulating nucleated red blood cells. centrilobular necrosis in the liver, extramedullary hematopoiesis in liver and spleen, and hemoglobin casts in kidney tubules are prominent histologic features. hemosiderin and lipofuscin often a ... | 1981 | 7344245 |
| dimensional selectivity of neurons in the dorsolateral visual area of the owl monkey. | | 1980 | 7407569 |
| molecular characterization of hla-a, b homologues in owl monkeys and other nonhuman primates. | mouse anti-hla-a, b monoclonal antibodies have been used to study the homologues of hla-a, b antigens in other primate species. immunoprecipitates of primate histocompatibility antigens from extracts of radioactively labeled lymphocytes were analyzed by sds-polyacrylamide electrophoresis. primate histocompatibility antigens appear to have similar molecular structure to human hla antigens. owl monkeys, which react polymorphically with some monomorphic anti-hla antibodies, showed biochemical diffe ... | 1980 | 7409864 |
| necrotizing myopathy associated with hemolytic anemia in owl monkeys (aotus trivirgatus). | in 40 owl monkeys with hemolytic anemia of unknown etiology, 37 had a myopathy characterized by focal or diffuse necrosis of sarcoplasm which was eosinophilic and floccular. phagocytosis of necrotic fibers and regenerative changes were also observed. the severity of lesions roughly paralleled the severity of anemia and of centrilobular hepatic necrosis assumed to be caused by hypoxia. that the myopathy was not caused by anemia per se was suggested by the finding of mild myopathy in 10 of 24 monk ... | 1980 | 7411158 |
| magnification, receptive-field area, and "hypercolumn" size in areas 3b and 1 of somatosensory cortex in owl monkeys. | | 1980 | 7411189 |
| on the organization of the retino-tecto-thalamo-telencephalic pathways in a chilean rodent; the octodon degus. | after performing eye enucleations or restricted lesions in the superior colliculus or the pulvinar nucleus, the degeneration patterns provoked by these procedures were analyzed by means of the nissl and the fink-heimer methods in 30 specimens of octodon degus. the pulvinar or lateroposterior nucleus can be subdivided into 3 regions (rostrolateral, rostromedial and caudal), on the basis of cytoarchitecture, tectofugal afferent and efferent connections to the cerebral cortex. in addition, this nuc ... | 1982 | 7059825 |
| visual response properties of neurons in four extrastriate visual areas of the owl monkey (aotus trivirgatus): a quantitative comparison of medial, dorsomedial, dorsolateral, and middle temporal areas. | 1. the response properties of 354 single neurons in the medial (m), dorsomedial (dm), dorsolateral (dl), and middle temporal (mt) visual areas were studied quantitatively with bar, spot, and random-dot stimuli in chronically implanted owl monkeys with fixed gaze. 2. a directionality index was computed to compare the responses to stimuli in the optimal direction with the responses to the opposing direction of movement. the greater the difference between opposing directions, the higher the index. ... | 1981 | 7218008 |
| owl monkey cell line. | | 1981 | 7233214 |
| development of plasmodium inui in the aotus trivirgatus monkey. | four splenectomized aotus trivirgatus griseimembra monkeys were affected with the os strain of plasmodium inui, a parasite of old world macaques. high parasite densities were obtained and two of the animals died. surviving animals maintained low to moderate level of chronic infections. three of the four animals produced parasitemias which infected anopheles dirus mosquitoes; oocyst densities were very low, however. | 1981 | 7241282 |
| circadian locomotor rhythms of the night monkey (aotus trivirgatus) under constant light conditions. | three quantities, circadian period, amount of activity, and ratio of activity time to rest time of circadian locomotor rhythms in the night monkey (aotus trivirgatus), were measured under the influence of two constant light intensities. when light intensity was increased from < 0.1 to 100 lx, the circadian period increased, showing that aschoff's rule can be valid for this dark active primate species. the ratio of activity time to rest time was shorter under 100 lx than under < 0.1 lx of continu ... | 1980 | 7419133 |
| auditory cortico-cortical connections in the owl monkey. | two tonotopically organized cortical fields, the primary (a1) and rostral (r) fields, comprise a core of auditory cortex in the owl monkey. injections of tritiated proline were made into each of these fields to determine their projections to the auditory fields in the ipsilateral and contralateral hemispheres using autoradiographic methods. neurons in r project to the rostromedial (rm) and primary fields in both hemispheres, and to the posterolateral (pl) and anterolateral (al) fields in the ips ... | 1980 | 7419746 |
| the excretion of gonadal steroids during the reproductive cycle of the owl monkey (aotus trivirgatus). | | 1980 | 7421227 |
| plasma concentrations of oestradiol-17 beta, oestrone, progesterone and testosterone during the ovarian cycle of the owl monkey (aotus trivirgatus). | oesterone, oestradiol-17 beta, progesterone and testosterone were measured by radioimmunoassay in daily plasma samples throughout the ovarian cycle in 4 female owl monkeys. clearly defined peaks of oestradiol-17 beta occurred at intervals of 15.5 +/- 0.56 days and confirmed the length of the cycle reported previously. progesterone rose on the day on the day of the oestradiol-17 beta to reach a maximum 4--6 days later, thereafter decreasing gradually to low levels before the onset of the next cyc ... | 1980 | 7431313 |
| interhemispheric connections of visual cortex in the owl monkey, aotus trivirgatus, and the bushbaby, galago senegalensis. | anatomical techniques have been used to map within visual cortex th pattern of degenerating axonal terminals produced by surgical section of the splenium of the corpus callosum in the owl monkey, aotus trivirgatus, and the bushbaby, galago senegalensis. previous studies in other species have shown that callosal inputs terminate preferentially in regions where the vertical meridian of the visual field is represented. such a correspondence can serve as a useful aid for locating the boundaries of v ... | 1980 | 7440796 |
| xx/"xo" sex determination system in a population of peruvian owl monkey, aotus. | the chromosome complement of a group of owl monkeys with typical pelagic features characteristic of aotus inhabiting the upper amazonian region in south america was analyzed by various band techniques. a diploid chromosome number of 2n = 52 is reconfirmed in the females. a y-autosome translocation resulting in a complement of 2n = 51 in the males constitutes a unique xx/"xo" sex chromosome system in this population. karotypic comparison of this peruvian aotus (2n - 52 female/51 male) with the bo ... | 1980 | 7440955 |
| remodelling of hand representation in adult cortex determined by timing of tactile stimulation. | the primate somatosensory cortex, which processes tactile stimuli, contains a topographic representation of the signals it receives, but the way in which such maps are maintained is poorly understood. previous studies of cortical plasticity indicated that changes in cortical representation during learning arise largely as a result of hebbian synaptic change mechanisms. here we show, using owl monkeys trained to respond to specific stimulus sequence events, that serial application of stimuli to t ... | 1995 | 7477291 |
| cell-mediated immunity in owl monkeys following inoculation with hepatitis a virus. | | 1995 | 7502862 |
| inhibition of complement-mediated cytolysis by the terminal complement inhibitor of herpesvirus saimiri. | herpesvirus saimiri (hvs) is a lymphotropic herpesvirus that induces t-cell transformation in vitro and causes lymphomas and leukemias in new world primates other than its natural host, the squirrel monkey. nucleotide sequence analysis of the hvs genome revealed two open reading frames with significant homology to genes for human complement regulatory molecules. one of these genes encodes a predicted protein (designated hvscd59) with 48% amino acid sequence identity to the human terminal complem ... | 1994 | 7507185 |
| the postnatal development of geniculocortical axon arbors in owl monkeys. | to characterize the postnatal development of geniculocortical axon arbor morphology in owl monkeys at a series of ages from birth to adulthood, individual arbors were bulk-filled with hrp in brain slice preparations and were reconstructed from serial sections. at all ages, cortical layers and sublayers were obvious. presumed m or magnocellular arbors were largely confined to layer iv alpha, but they also extended into layer iiic (ivb of brodmann, 1909); presumed p or parvocellular arbors were al ... | 1994 | 7516701 |
| association of a choroidal ganglion cell plexus with the fovea centralis. | after recently demonstrating an nadph-diaphorase-, nitric oxide synthase (nos)-positive ganglion cell plexus in the human choroid that was absent in rabbit and rat eyes, the authors extended their comparative studies to nonhuman primates and to subprimate mammals. | 1994 | 7528181 |
| noncontact laser photothermal keratoplasty. iii: histological study in animal eyes. | laser photothermal keratoplasty has been studied as a potential refractive procedure. the purpose of this study is to investigate the histological response to various laser treatments including geometrical patterns, radiant exposure levels, and pulse numbers. | 1994 | 7530102 |
| thalamic connections of the primary motor cortex (m1) of owl monkeys. | to determine the relative contributions of transthalamic cerebellar and pallidal projections to the primary motor cortex (m1) of owl monkeys, we examined the thalamic labeling resulting from injections of fluorescent tracers and wheatgerm agglutinin/horseradish peroxidase conjugate (wga-hrp) into regions of m1 identified by intracortical microstimulation. injections were placed in the major somatotopic divisions of m1 (the hindlimb, trunk, forelimb, and face representations) and in the caudal an ... | 1994 | 7532193 |
| inositol 1,4,5-trisphosphate receptors: immunocytochemical localization in the dorsal cochlear nucleus. | in the cochlear nucleus of mammals, the relatively homogeneous responses of auditory nerve fibers are transformed into a variety of different response patterns by the different classes of resident neurons. the spectrum of these responses is hypothesized to depend on the types and distribution of receptors, ion channels, g proteins, and second messengers that form the signaling capabilities in each cell class. in the present study, we examined the immunocytochemical distribution of the inositol 1 ... | 1995 | 7560273 |
| comparative and functional myology of the prehensile tail in new world monkeys. | the caudal myology of prehensile-tailed monkeys (cebus apella, alouatta palliata, alouatta seniculus, lagothrix lagotricha, and ateles paniscus) and nonprehensile-tailed primates (eulemur fulvus, aotus trivirgatus, callithrix jacchus, pithecia pithecia, saimiri sciureus, macaca fascicularis, and cercopithecus aethiops) was examined and compared in order to identify muscular differences that correlate with osteological features diagnostic of tail prehensility. in addition, electrophysiological st ... | 1995 | 7595958 |
| architectonics, somatotopic organization, and ipsilateral cortical connections of the primary motor area (m1) of owl monkeys. | the ipsilateral cortical connections of primary motor cortex (m1) of owl monkeys were revealed by injecting wga-hrp and fluorescent tracers into m1 sites identified by intracortical microstimulation. in some of the same animals, the extent and somatotopic organization of m1 was determined by making detailed microstimulation movement maps and relating the results to cortical architectonics. thus, delineation of m1 was based on a combination of physiological and anatomical characteristics. m1 comp ... | 1993 | 7684050 |
| analysis of retinotopic maps in extrastriate cortex. | two new techniques for analyzing retinotopic maps--arrow diagrams and visual field sign maps--are demonstrated with a large electrophysiological mapping data set from owl monkey extrastriate visual cortex. an arrow diagram (vectors indicating receptive field centers placed at cortical coordinates) provides a more compact and understandable representation of retinotopy than does a standard receptive field chart (accompanied by a penetration map) or a double contour map (e.g., isoeccentricity and ... | 1994 | 7703687 |
| hyperimmune globulins in prevention and treatment of respiratory syncytial virus infections. | respiratory syncytial virus (rsv) is an important community and nosocomial respiratory pathogen for infants and young children. rsv causes especially severe disease in the prematurely born or those with chronic cardiopulmonary diseases. elderly persons and those with t-cell deficiencies, such as bone marrow transplant recipients, are also at high risk for serious lower respiratory tract infections. to date, prevention of rsv infections by vaccination has proven elusive and no preventive drugs ex ... | 1995 | 7704893 |
| entry of coronavirus into primate cns following peripheral infection. | a previous report demonstrated that intracerebrally inoculated coronavirus produced cns disease in two species of primates (murray rs, cai g-y, hoel k, et al., virol 1992; 188: 274-84). we were therefore interested in testing the potential of coronaviruses to infect primate cns tissue following peripheral inoculation. four owl monkeys (aotus trivirgatus) were inoculated intranasally and ocularly and four were inoculated intravenously with coronavirus jhm omp1 (murray rs, cai g-y, hoel k, et al., ... | 1994 | 7815918 |
| the natural history of hepatitis a: the potential for transmission by transfusion of blood or blood products. | a study of the natral history and risk factors for hepatitis a can shed light on the potential for contamination of plasma concentrate with hepatitis a virus (hav). according to the long-term sentinel counties study conducted by alter and colleagues at the centers for disease control and prevention in atlanta, the most frequently reported risk factors for hav infection are living with a patient who has hepatitis, homosexual activity, and close contact with young children. international travel to ... | 1994 | 7831865 |
| optical imaging reveals the functional architecture of neurons processing shape and motion in owl monkey area mt. | we have used optical imaging based on intrinsic signals to explore the functional architecture of owl monkey area mt, a cortical region thought to be involved primarily in visual motion processing. as predicted by previous single-unit reports, we found cortical maps specific for the direction of moving visual stimuli. however, these direction maps were not distributed uniformly across all of area mt. within the direction-specific regions, the activation produced by stimuli moving in opposite dir ... | 1994 | 7838851 |
| architectonic subdivisions of the motor thalamus of owl monkeys: nissl, acetylcholinesterase, and cytochrome oxidase patterns. | as the first part of an investigation of the motor thalamus and its cortical connections in the owl monkey, a new world anthropoid primate, we studied thalamic architecture by using stains for nissl, acetylcholinesterase (ache), and cytochrome oxidase (co), in order to identify subdivisions of the ventrolateral thalamic region as well as other nuclei with motor connections. material was obtained from brains cut in the frontal, horizontal, and parasagittal planes. our results indicate that the ve ... | 1994 | 7860788 |
| plasmodium falciparum: passive immunization of aotus lemurinus griseimembra with immune serum. | owl monkeys (aotus lemurinus griseimembra) were immunized against plasmodium falciparum by infection and drug cure. after challenge, 3 of 4 monkeys developed extended prepatent periods and low grade parasitemias followed by self cure. the fourth monkey did not develop a patent infection. immune monkey serum passively transferred at the time of challenge conferred immunity to 20 naive monkeys. immunity was characterized by extended prepatent periods in 19 monkeys, low levels of parasitemia (< or ... | 1995 | 7895839 |
| the lecithodendriid trematode phaneropsolus orbicularis from the duodenum of an owl monkey. | | 1994 | 7898026 |
| interhemispheric connections in neonatal owl monkeys (aotus trivirgatus) and galagos (galago crassicaudatus). | interhemispheric connections were studied by injecting a mixture of horseradish peroxidase (hrp) and wheatgerm agglutinin conjugated with horseradish peroxidase (wga-hrp) into multiple sites in dorsolateral occipital and parietal cortex of one cerebral hemisphere of three galagos (galago crassicaudatus) and two owl monkeys (aotus trivirgatus) within seven days of birth. cortex was either separated from the rest of the brain, flattened and cut parallel to the surface to aid reconstructing surface ... | 1994 | 7922590 |
| serum and urine biochemical diversity among wild-caught and colony-born aotus nancymae. | serum and urine analytes were compared between adult wild-caught and adult colony-born owl monkeys (aotus nancymae), to determine if normative clinical pathology data were similar. significant differences (p < or = 0.05) were noted in serum protein, glucose, sodium, urine calcium, calcium clearance, and fractional clearance of calcium between the two groups. the results suggest that reference data for feral owl monkeys is not completely applicable to colony-born animals, however, the differences ... | 1994 | 7932636 |
| possible spontaneous mycobacteriosis in an owl monkey. | | 1994 | 7932642 |
| ultrasound-guided cholecystocentesis in the owl monkey. | bile samples were obtained from adult owl monkeys by ultrasound-guided percutaneous cholecystocentesis, using a transhepatic approach. sampling frequency was once weekly over a 5-week period. clinical recovery from each procedure was rapid. animal body weights fluctuated within 22% of baseline over the study period, but maximal weight loss in any animal was less than 3% at the study's end. at necropsy, gross lesions in the liver and gallbladder were minimal. histologic examination revealed mild ... | 1994 | 7983850 |
| an agarose gel electrophoretic method for analysis of hyaluronan molecular weight distribution. | an electrophoretic method is described for determining the molecular weight distribution of hyaluronan (ha). the method involves separation of ha by electrophoresis on a 0.5% agarose gel, followed by detection of ha using the cationic dye stains-all (3,3'-dimethyl-9-methyl-4,5,4'5'-dibenzothiacarbocyanine). the recommended sample load is 7 micrograms. calibration of the method with ha standards of known molecular weight has established a linear relationship between electrophoretic mobility and t ... | 1994 | 8080084 |
| [experimental models of hepatitis a in macaques using viral strains isolated from man and monkeys]. | experimental hepatitis a (ha) models were obtained in macaca monkeys (15 m. fascicularis and 4 m. mulatta) by means of the strains of hepatitis a virus (hav) isolated from the feces of a patient (hav-h) and of spontaneously infected m. mulatta (hav-mm) and green monkeys cercopithecus aethiops (hav-ca). irrespective of the strains used all seronegative macaca monkeys developed ha after intravenous-oral inoculation with the following patterns: elevation of the serum alanine aminotransferase level, ... | 1994 | 8087252 |