| intestinal parasites among karitiana indians from rondônia state, brazil. | gravity sedimentation parasitological examinations were performed in stool samples from 111 karitiana indians from rondônia state, brazilian amazon basin. intestinal parasites were found in 43 samples (38.7%). ascaris lumbricoides was the most prevalent helminth species (18.9%). egg counts in samples positive for ascaris suggested an overdispersed distribution of worm burdens in the host population. age-distribution pattern of intestinal parasites among karitiana indians was found to be rather u ... | 1992 | 1342074 |
| a phosphorylcholine idiotype related to tepc 15 in mice infected with ascaris suum. | a serum component, binding antigens having phosphorylcholine (pc) determinants were induced in several strains of mice by infection with ascaris suum. this component was isolated and demonstrated to be an igm (k) anti-pc antibody having idiotypic determinants in common with the iga pc-binding myeloma protein tepc 15. rabbit anti-idiotypic antisera prepared with this component had idiotypic specificity for tepc 15 and cross-idiotypic recognition of mopc 167 and mcpc 603, all iga pc-binding myelom ... | 1976 | 1254963 |
| the resolution of ascaris cuticle collagen into three chain types. | reduced and methylated collagen from ascaris lumbricoides cuticle was resolved into three major components by chromatography on phosphocellulose. the components have similar molecular weights of about 52,000 by sedimentation equilbrium and molecular sieve chromatography, but they have different amino acid compositions. since they do not appear to be stoichiometrically related, they apparently represent chains from collagens of more than one type. all three chains contain about 27 residue % glyci ... | 1976 | 1259947 |
| [presence of intestinal parasites in vegetables sold in the metropolitan region of são paulo, sp, brazil. i--search of helminths]. | vegetables in natura, commercially traded in the metropolitan area of s. paulo, were analysed by the appropriate methodology with a view to discovering an identifying the paths of transmission of enteroparasites of medical interest. the vegetables under study consisted of 50 samples of each variety listed below: lettuce (lactuca sativa)-oily leaves and crisphead varieties, endive (chicorium sp) and water-cress (nasturtium officinale). results showed high rates of contamination in all the vegetab ... | 1992 | 1342513 |
| the mediation of tissue eosinophilia in hypersensitivity reaction. i. isolation of two different chemotactic factors from dnp-ascaris extract-induced skin lesion in guinea-pig. | in an active cutaneous anaphylaxis induced by dnp-ascaris extract in guinea-pig, tissue eosinophilia manifested two phases; the early and mild phase became maximal in about 6 h, while the delayed and intense phase in 18-24 h. skin extracts from the lesions exhibited chemotactic activities for eosinophils, respectively comparable to the intensity of tissue eosinophilia in each phase; and two different chemotactic factors for eosinophils of skin extracts were separated by gel filtration on sephade ... | 1976 | 1262051 |
| bronchial challenge of tropical asthmatics with ascaris lumbricoides. | despite the fact that helminthic parasites can stimulate strong immediate hypersensitivity reactions, it is uncertain whether these are relevant to the development of allergic disease in infected patients. in order to examine this possibility, we tested 20 informed chronic asthmatic patients from an ascaris-endemic area by bronchial challenge with a partially purified extract of this parasite. sequential measurements were made of both the forced expiratory volume in the first second (fev1) and t ... | 1992 | 1342890 |
| interrelationship between schistosomiasis and concomitant diseases. | the biological literature contains many examples of mutual influences between different species of parasites, especially with respect to concomitant helminth infections. several situations are known in which the association of infection by schistosoma mansoni with other pathogens in the same host results in a type of disease which differs from the simple summation of the individual effects of each infection. the present study concerns concomitant infections involving s. mansoni and enterobacteri ... | 1992 | 1343911 |
| [evaluation of helminth carrier rates among foreign workers (author's transl)]. | the evaluated helminth carrier rate among foreign workers give rise to many problems under socio-economic, hygienic and occupational aspects. the evaluation of helminth infestation is connected with considerable uncertainty. based on the author's examinations these problems are critically investigated from the point of view of both, the employer and the employee. it is shown in tables that in the institute of hygiene and microbiology of würzburg during 1973/1974 497/702 respectively faecal exami ... | 1975 | 1214697 |
| predisposition and ascaris infection. | | 1992 | 1351978 |
| a comparison of post-mortem analysis of helminths with faecal egg counts. | intestinal helminth infections are very common amongst residents of the colombo area. most common by post-mortem examination of 104 cases of sudden death were trichuris trichiura (97.1%), necator americanus (88.5%), enterobius vermicularis (77.9%) and ascaris lumbricoides (40.4%). trematode and cestode infections were not encountered except a single case of h. diminuta infection. a comparison of the results obtained by the direct smear method for examining stools missed cases harbouring gravid f ... | 1975 | 1216302 |
| larva migrans syndrome: toxocara, ascaris, or both? | | 1992 | 1354301 |
| levocabastine: pharmacological profile of a highly effective inhibitor of allergic reactions. | levocabastine, selected from a series of cyclohexylpiperidine derivatives protects rats from compound 48/80-induced anaphylactic shock for at least 16 h at the oral dose of 0.0015 mg/kg. at the same dose histamine skin reactions and at slightly higher doses passive cutaneous anaphylactic reactions are inhibited. blockade of passive cutaneous anaphylactic reactions is obtained with levocabastine, despite absence of peripheral serotonin antagonism and any other known non-specific action that may f ... | 1992 | 1354927 |
| canine in vivo tracheal chemotaxis of eosinophils to antigen in sensitized dogs: inhibition by a steroid, a systemic lazaroid u-78517f, and several topical h1 antihistamines. | inflammation of the airways contributes to the multicomponent disease known as asthma. the primary cells that infiltrate the airway in response to antigen exposure are neutrophils and eosinophils. eosinophils have been implicated in much of the histopathology of the airway following infiltration and degranulation. we used topical antigen exposure in the trachea of sensitized beagle dogs to study the kinetics of eosinophil infiltration with a modified double balloon endotracheal tube technique. a ... | 1992 | 1355641 |
| chromatographic and immunological characterisation of neuropeptide y-like and pancreatic polypeptide-like peptides from the nematode ascaris suum. | 1. immunoreactivity (ir) towards neuropeptide y (npy) and pancreatic polypeptide (pp) has previously been demonstrated in nematodes by immunocytochemistry (icc). 2. the pp- and npy-ir in the nematode parasite ascaris suum were analysed using hplc and radioimmunoassays (rias) specific for either peptide. 3. quantitative ria data on the distribution of these irs in the parasite disagreed with icc data suggesting that different tissue treatments used in the two techniques lead to different antigen ... | 1992 | 1360356 |
| [therapeutic trial with a single oral dose of pyrantel pamoate in infections by enterovirus vermiculosis and ascaris lumbricoides]. | | 1975 | 1219940 |
| [role of mollusks as benthos components in the purification of water bodies from the eggs of ascaris suum]. | fresh water mollusks galba palustris and bithynia tentaculata feed on ascaris eggs, destroy them (10 to 20%) and hinder their development as compared to control ones. thus, this mollusks participate in the purification of water bodies from ascaris eggs. eggs swallowed by mollusks of the genus radix develop normally. consequently radix serve for scattering eggs over the bottom of the water body. | 1975 | 1237854 |
| pulmonary ascariasis in tropical communities. | to determine the incidence of loeffler's syndrome in a tropical region, a survey was conducted over a 1-year period in two locations in colombia, south america, one inland and urban (cali), the other rural and coastal (guapi). among 700 hospitalized patients, 12,000 patients coming to health centers, and 44 families with 328 members, 4 cases of loeffler's syndrome were found--3 during the survey and 1 before it began. only one was typical and of some severity. none of the family members develope ... | 1975 | 1238026 |
| standardization of dot-elisa for the serological diagnosis of toxocariasis and comparison of the assay with elisa. | the dot-enzyme-linked immunosorbent assay (dot-elisa) was standardized using somatic (s) and excretory-secretory (es) antigens of toxocara-canis for the detection of specific antibodies in 22 serum samples from children aged 1 to 15 years, with clinical signs of toxocariasis. fourteen serum samples from apparently normal individuals and 28 sera from patients with other pathologies were used as controls. all samples were used before and after absorption with ascaris suum extract. when the results ... | 1992 | 1307410 |
| massive infestation by ascaris lumbricoides of the biliary tract: report of a successfully treated case. | this is a report of a 25 years old black woman from the city of são paulo, brazil, who developed acute obstructive cholangitis of ascaris lumbricoides with septicemia and multiple hepatic abscesses. the patient had sickle cell trait and normal delivery 3 months ago. massive infestation of the biliary tract by ascaris lumbricoides was diagnosed by abdominal ultrasonography and endoscopic retrograde cholangiography. sixty worms were removed from the common bile duct and hepatic abscesses were drai ... | 1992 | 1307412 |
| pharmacological profiles of the gaba and acetylcholine receptors from the nematode, ascaris suum. | the pharmacological profiles of the acetylcholine and gaba receptors of ascaris muscle have been investigated. acetylcholine excites the muscle through activation of a nicotinic receptor which resembles the mammalian ganglionic receptor. dmpp is a potent agonist and alpha-bungarotoxin is a weak antagonist. gaba inhibits the muscle through activation of a chloride-linked receptor which in terms of agonist profile resembles the mammalian gaba-a receptor. however, bicuculline is inactive and picrot ... | 1992 | 1338558 |
| low concentrations of neuroactive peptides modulate cholinergic transmission and cyclic amp levels in helix aspersa. | 1. fmrfamide and the catch relaxing peptide (carp) at 0.01-0.1 nm modulate acetylcholine (ach) induced currents of identified neurons of helix aspersa, but have no direct effect on membrane current and conductivity. 2. both fmrfamide and carp noncompetitively inhibit ach cl- responses while having either no effect or increasing ach na+/k+ response. 3. the inhibitory effect of fmrfamide and carp on the ach cl- response was eliminated following pretreatment with forskolin (20 microm), an activator ... | 1992 | 1338559 |
| demonstration and possible function of nadh:nad+ transhydrogenase from ascaris muscle mitochondria. | mitochondria from the muscle of ascaris lumbricoides var. suis function anaerobically. nadh is generated in the intermembrane space as a consequence of the "malic" enzyme reaction. it has been suggested that this reducing equivalent in the form of hydride ion, would be translocated across the inner membrane in order to mediate atp generation via the fumarate reductase reaction. in accord with this suggestion, intact ascaris mitochondria showed appreciable nadh oxidase activity. sonication result ... | 1976 | 1262321 |
| studies in intestinal parasitic disease agents in stools of people in a rural area of nigeria. | a summary of 300 villagers who reported at the parasitology laboratory of the school of medical laboratory technology (s.m.l.t) vom, plateau state, nigeria was carried out for the presence of parasites' cysts, eggs, or larva. of the 300 faecal samples examined using the light microscope after formal-ether centrifugation, 127 (42.3%) harboured one or more parasites. the parasites identified and their prevalent rates were: entamoeba coli (19.0%) necator americanus (17.0%); entamoeba histolytica (4 ... | 1992 | 1390369 |
| ascaris lumbricoides: an unusual cause of shunt infection. | two cases of delayed shunt infection attributable to the abdominal complications of ascaris lumbricoides infestation are reported. the first child presented with a peritoneal shunt catheter protruding through the anus and the second patient was found to have two live worms around the cephalic shunt tubing. both had enteric shunt infections which responded well to therapy. the epidemiology and treatment of ascariasis are briefly discussed. | 1992 | 1394273 |
| [treatment of soil-transmitted helminth infections by anthelmintics in current use]. | the efficacy of broad-spectrum anthelmintics in current use was studied in hengshan county, hunan province. the vermicides under study include albendazole (400mg, single dose), mebendazole composite (mebendazole 100 mg and levamisole 25mg bid x 3d), oxantel pyrantel pamoate composite (pyrantel pamoate 150 mg and oxantel pamoate 150 mg bid x 2d), and pyrantel pamoate composite (base 10 mg/kg, single dose). therapeutic effect assessed 2 weeks after medication revealed ascaris egg negative rates or ... | 1992 | 1394916 |
| cuticular reactivity of the early larval stages of ascaris suum: adhesion and degranulation of polymorphonuclear leukocytes of the surface of opsonized larvae of a. suum. | | 1976 | 1279081 |
| patent infections of ascaris suum in pigs: effect of previous exposure to multiple, high doses of eggs and various treatment regimes. | fifty-four crossbred, 4-week-old pigs divided into nine equal groups were used to test whether multiple inoculations with high numbers of a. suum eggs with or without anthelmintic would result in patent infections. all pigs exposed to multiple prechallenge inoculations of 500, 1000, 2000, 5000, 10,000 and 20,000 and challenged orally 2 weeks later with 10,000 eggs harboured adult worms. when prechallenge infections were removed by pyrantel tartrate treatment the animals were more susceptible to ... | 1992 | 1399243 |
| a possible genetic factor influencing protection from infection with ascaris lumbricoides in nigerian children. | an epidemiological study of ascaris lumbricoides infections was carried out in primary school children aged 5-16 yr from ile-ife, nigeria. intensity of infection was assessed directly by means of counting worms passed during a 48-hr period after chemotherapy. reinfection patterns of a. lumbricoides were assessed at 2 6-mo intervals and statistical evidence of predisposition to infection status was obtained. an investigation of 3 groups of children who were judged to be predisposed not to be infe ... | 1992 | 1403439 |
| inhibitory reflex during bronchoconstrictions induced by histamine and ascaris suum antigen. | we investigated the involvements of sympathetic and nonadrenergic nervous systems in the inhibitory reflex following bronchoconstriction in dogs. inhalations of a 0.00125% solution of histamine and ascaris suum antigen (3 mg protein) to the bronchial side induced reflex tracheal constriction following bronchoconstriction. an intra-arterial infusion of 5 micrograms/min of atropine to the tracheal site changed the reflex tracheal constrictions by histamine and antigen inhalations into tracheal dil ... | 1992 | 1405031 |
| [ascariasis of the cervix]. | the authors report a case of ascaris lumbricoïdes located in the cervix uterus of a patient suffering from gonococcal salpingitis. reviewing the literature, they conclude that the most likely way to the parts genitals was a transanal migration toward vagina. | 1992 | 1406217 |
| ascaris lumbricoides and peak expiratory flow rates in children aged 5-15 years. | | 1992 | 1406404 |
| substance p as a potent stimulator of sneeze responses in experimental allergic rhinitis of guinea pigs. | substance p was examined for sneeze-inducing activity and its involvement of sneeze responses in experimental allergic rhinitis. substance p, dripped into a nostril of guinea pigs, at concentrations of 100 pm and above induced sneezing in a dose-dependent fashion. the activity of substance p was not affected by the previous subcutaneous injections of capsaicin that depleted substance p in nerve fibers. histamine induced sneezing at concentrations of 30 mm and above and the activity was reduced b ... | 1992 | 1284191 |
| distribution of a fluorescent ivermectin probe, bodipy ivermectin, in tissues of the nematode parasite ascaris suum. | a fluorescent derivative of the anthelmintic ivermectin (4''-5,7-dimethyl bodipy proprionylivermectin, referred to hereafter as bodipy ivermectin) was synthesized for an investigation of the distribution of avermectins. injected into adult ascaris suum at doses greater than 0.1 micron per worm, it produced a dose-dependent immobilization. fluorescent microscopy of frozen sections revealed the distribution of the probe in the whole nematode. staining of collagenase-isolated muscle cells was studi ... | 1992 | 1409535 |
| antigen-induced late-phase airway obstruction in the guinea pig? | hartley or dunkin-hartley guinea pigs (n = 136) were actively sensitized to ovalbumin or ascaris suum protein by five different regimes. specific airway resistance (sr(aw)) was measured in conscious animals by a plethysmographic procedure before, immediately following and at various intervals (up to 96 h) after aerosolized antigen or vehicle challenge. each sensitization and challenge regime produced an immediate allergic response with positive responses (defined as a 2-fold increase in sr(aw)) ... | 1992 | 1295358 |
| lack of late-phase airway responses in conscious guinea pigs after a variety of antigen challenges. | guinea pigs were actively sensitized by parenteral injections of ovalbumin (oa), house dust extract (hd) or ascaris suum extract (as) in a variety of multidose regimens. at least 3 weeks after the initial sensitization injection, aerosols of the appropriate antigen were administered to conscious guinea pigs in a double-chamber body plethysmograph. oa elicited the most consistent and intense bronchoconstriction (bc) as measured by decreases in specific airway conductance (sgaw). the airway respon ... | 1992 | 1295368 |
| anti-inflammatory properties of zinc protoporphyrin disodium (zn-pp-2na). | anti-inflammatory properties of zinc protoporphyrin disodium (zn-pp-2na) were studied. zn-pp-2na exhibits anti-allergic action against type iii and iv reactions (passive arthus reaction in rats and tuberculin-induced footpad reaction in mice), but does not affect type i and ii reactions (homologous passive cutaneous anaphylaxis in mice and reversed cutaneous anaphylaxis in rats). zn-pp-2na also clearly inhibits type ii collagen-induced arthritis in mice. the agent inhibits general arthritis symp ... | 1992 | 1295376 |
| immunocytochemical and electrophysiological investigations of central neurones in the parasitic nematode ascaris suum. | here we report on preliminary investigations into the morphological, neurochemical and electrophysiological characteristics of central neurones in the parasitic nematode ascaris suum. the neurones do not display all or none action potentials and apparently have low resting membrane potentials. neurones have been shown to respond to acetylcholine. immunoreactivity to a diverse range of neuropeptides has been demonstrated. | 1992 | 1299113 |
| [the use of sodium azide as a fecal preservative for studying the eggs of schistosoma mansoni and of other helminths by the kato-katz method: a study in an endemic area]. | in two aliquots of 208 samples of stool, tests have been made by the kato-katz method, one being made after the use of 0.2mg of sodic azide for 200mg, and the other without the aforesaid conservant. the resulted percentages with or without the conservant were, respectively, for ancylostomideos: 12.5 and 25.9; for ascaris lumbricoides: 71.6 and 72.5; for schistosoma mansoni: 7.6 and 17.7, and for trichuris trichiura: 86 and 85. the count of the eggs with and without the conservant was, respective ... | 1992 | 1308947 |
| extracellular recordings from the motor nervous system of the nematode, ascaris suum. | 1. the close association of muscle and neurons in ascaris suum makes it difficult to determine whether spikes recorded from nerve cords originate in muscle or neurons. we have developed criteria that distinguish muscle and neuronal activity. there are two categories of extracellular spikes. 2. the first category consists of spikes with a wide range of amplitudes, marked by large spikes. these spikes, which can be recorded over lateral muscle and over the dorsal and ventral nerve cords, are aboli ... | 1992 | 1328624 |
| pharmacology of mk-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor. | mk-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid, previously l-686,708) is a potent inhibitor of leukotriene (lt) biosynthesis in intact human and elicited rat polymorphonuclear leukocytes (pmnls) (ic50 values 3.1 and 6.1 nm, respectively) and in human, squirrel monkey, and rat whole blood (ic50 values 510, 69, and 9 nm, respectively). mk-0591 had no effect on rat 5-lipoxygenase. mk-0591 has a high affinity for 5-lipoxygenase activ ... | 1992 | 1330258 |
| comparative prevalences of ascaris lumbricoides, trichuris trichiura and hookworm infections and the prospects for combined control. | programmes to control ascaris lumbricoides, trichuris trichiura and hookworm infections have often been targeted at each infection separately, but the advent of benign and broad-spectrum anthelmintics suggests that combined control may be feasible. the extent to which the infections co-occur in communities will determine the need for, and potential benefits of, such a combined approach. this paper examines the comparative distribution of the three geohelminths in different geographical areas and ... | 1992 | 1437273 |
| the 5-lipoxygenase inhibitor zileuton blocks antigen-induced late airway responses, inflammation and airway hyperresponsiveness in allergic sheep. | leukotrienes are thought to be involved in allergen-induced airway responses. to test this hypothesis we used a newly described 5-lipoxygenase inhibitor, zileuton, and examined its effect on antigen-induced early and late bronchial responses, airway inflammation and airway hyperresponsiveness in allergic sheep. early and late responses were determined by measuring specific lung resistance (srl) before and serially for 8 h after antigen challenge. airway inflammation was assessed by bronchoalveol ... | 1992 | 1330588 |
| voltage-activated currents in somatic muscle of the nematode parasite ascaris suum. | 1. voltage-activated currents in cell bodies of the somatic muscle cells of ascaris suum were studied using a two-microelectrode voltage-clamp technique. cells recorded from had resting membrane potentials around -35 mv and had input conductances in the range 1-10 micros. 2. in cells bathed in artificial perienteric fluid, depolarizing steps from a holding potential of -35 mv elicited outward currents at a threshold of -15 mv. these currents had inwardly directed inflections on the rising phase, ... | 1992 | 1336792 |
| the effect of repeated chemotherapy on the prevalence and intensity of ascaris lumbricoides and trichuris trichiura infection. | the prevalence and intensity of intestinal nematode infections were assessed during 3 anthelminthic interventions in an urban community in malaysia. the prevalence levels of ascaris lumbricoides at interventions 1, 2 and 3 were 30.6%, 18.9% and 15.5%, respectively and the mean intensities were 1.9, 0.75 and 0.81 worms per person. for trichuris trichiura, the prevalence levels at interventions 1, 2 and 3 were 46.9%, 21.6% and 15.7%, respectively. the mean intensities for t. trichiura at intervent ... | 1992 | 1439974 |
| pulmonary vascular response to anaphylaxis in isolated canine lungs. | we determined changes in vascular resistance and microvascular permeability during anaphylactic reaction in isolated canine lungs perfused at constant pressure with autologous blood. in lungs with anaphylaxis induced by an intra-arterial injection of ascaris suum antigen (10 mg), pulmonary vascular resistance and capillary pressure assessed as double occlusion pressure increased transiently by 10 times and 6.3 mmhg, respectively. pre- to postcapillary vascular resistance ratio decreased from 0.8 ... | 1992 | 1443218 |
| a monoclonal antibody-based immunodiagnostic assay for onchocerciasis. | five murine monoclonal antibodies raised against onchocerca volvulus cuticular extracts and termed movs (1-4 and 6) were selected based on reactivity with o. volvulus cryosections, and non-reactivity with cryosections of human skin and/or nodular tissue. two others movs 5 and 7 reacted with both. using the peroxidase-anti- peroxidase (pap) histochemical method, the target epitopes of mov 1 were located in the cuticle's basal and cortical layers, those of mov 2 in the cortical layer; whilst mov 3 ... | 1992 | 1381517 |
| relationship of airway responsiveness to agents causing bronchoconstriction and cough in sensitized guinea-pigs. | the relationship between airway responsiveness to bronchoconstrictor- and cough-inducing stimuli has been examined in ascaris suum-sensitized conscious guinea-pigs. guinea-pigs were sensitized to ascaris suum [4000 pnu and 100 mg al(oh)3 i.p. on days 1 and 7] and then challenged with aerosolized antigen on days 21, 28 and 35. at day 35, antigen-exposure produced an early bronchoconstrictor response (ebr) and in about 50% of the animals also a late bronchoconstrictor response (lbr) commencing 4-8 ... | 1992 | 1446141 |
| cryptosporidiosis among patients with acquired immunodeficiency syndrome in zulia state, venezuela. | we studied the prevalence of cryptosporidium in 29 patients with acquired immunodeficiency syndrome (aids) from zulia state, venezuela. they ranged in age from five months to 46 years. two were children and 27 were adults, of which six were women. of the 21 men, 66.6% reported homosexual behavior. three stool samples from each patient were examined, and modified ziehl-neelsen carbolfuchsin staining of formalinether stool concentrates was used to identify cryptosporidium oocysts. to detect the pr ... | 1992 | 1449198 |
| the prevalence and intensity of soil-transmitted helminthiases in rural communities in southern nigeria. | an investigation of the prevalence and intensity of soil-transmitted helminthiases was undertaken in four villages in oyo state, nigeria. diagnosis was based on examination of stool samples for the presence of helminth ova in all age classes. the prevalence of ascaris lumbriocoides ranged from 61.5-72.2%, of trichuris trichiura from 65-74%, and of hookworm from 52.4-63% depending on the village concerned. intensity, assessed indirectly as the mean eggs per gram of faeces (epg), varied with regar ... | 1992 | 1449276 |
| human helminthosis in a rural community of plateau state, nigeria. | urine and faecal samples were obtained from 1,517 people in fier, a typical rural village in plateau state, nigeria, for a parasitological survey among the population. 643 (42.39%) persons were found to be infected with altogether 9 helminths, namely: ascaris lumbricoides, hookworm, taenia sp., trichuris trichiura, enterobius vermicularis, schistosoma mansoni, s. haematobium, hymenolepis nana and strongyloides stercoralis. age and religion as opposed to sex, type of sewage system, and type of ho ... | 1992 | 1456465 |
| the impact of schistosoma haematobium infection and of praziquantel treatment on the growth of primary school children in bertoua, cameroon. | our objective was to determine in a cameroonian school population the effect of mild to moderate s. haematobium infection intensity on growth and development of children before and 6 months after praziquantel treatment. previous studies have yielded contradictory results. children from bertoua schools were divided into four study groups: heavily infected (> 500 eggs 10 ml-1), moderately infected (1-499 eggs 10 ml-1) treated with praziquantel, a similar group treated with placebo, and an uninfect ... | 1992 | 1460700 |
| evaluating measures to control intestinal parasitic infections. | intestinal parasitic infections are among the most common infections of humans in developing countries, but the resources available for their control are severely limited. careful evaluation of control measures is essential to ensure that they are cost-effective. the evaluation of the effects of control on intestinal helminths and intestinal protozoa requires an understanding of the different epidemiological patterns of these two groups of parasites. the transmission dynamics and morbidity assoc ... | 1992 | 1462652 |
| prevalence of entamoeba histolytica and other intestinal parasites in a community from maracaibo, venezuela. | the prevalences of entamoeba histolytica and other intestinal parasites were assessed in a suburban community of maracaibo, venezuela, by examination of a stool specimen from each of 342 individuals, using iron-haematoxylin stained faecal smears and formalin-ether concentration. the overall parasitic infection rate was 80.4%, and 65.8% of the population had multiple infections. the overall amoebic infection rate, which was highest in female adults, averaged 39.7%. the e. histolytica infection ra ... | 1992 | 1463357 |
| a survey of the intestinal helminths of refugees in juba, sudan. | a parasitological survey of refugees based in juba, sudan, involving 241 faecal samples, revealed that 66% of the population harboured intestinal helminths. the most commonly found infection was hookworm (36%), followed by schistosoma mansoni (26%), strongyloides stercoralis (20%), hymenolepis nana (11%), ascaris lumbricoides (1.2%), trichuris trichiura (0.8%) and taenia sp. (0.4%). many of the specimens (42%) harboured a single infection, 21% had double, 2% triple and 1% quadruple infections. p ... | 1992 | 1463359 |
| a longitudinal study on anthropometric and clinical development of indian children adopted in sweden. ii. growth, morbidity and development during two years after arrival in sweden. | one hundred and fourteen consecutively recruited children adopted from india (60% girls) to sweden were studied during 2 years after arrival, with examinations monthly the first 6 months and thereafter every 3 months. sixty-two percent were below 1 year of age at arrival. there was a mean increase from -2.2 standard deviation scores (sds) height/age to -0.7 sds during the two years, and a similar development for weight/age, with no significant difference between boys and girls. the weight/height ... | 1992 | 1381851 |
| interaction of u6 snrna with a sequence required for function of the nematode sl rna in trans-splicing. | nematode trans-spliced leader (sl) rnas are composed of two domains, an exon [the 22-nucleotide spliced leader] and a small nuclear rna (snrna)-like sequence. participation in vitro of the spliced leader rna in trans-splicing reactions is independent of the exon sequence or size and instead depends on features contained in the snrna-like domain of the molecule. chemical modification interference analysis has revealed that two short sequence elements in the snrna-like domain are necessary for sl ... | 1992 | 1465612 |
| immunologic mast cell-mediated responses and histamine release are attenuated by heparin. | heparin has been shown to act as a competitive inhibitor of inositol 1,4,5-triphosphate (insp3) receptors in various cell types. because insp3 is one of the second messengers involved in stimulus-secretion coupling in mast cells, it is possible that heparin may inhibit mast cell-mediated reactions. therefore, in allergic sheep, we tested this hypothesis in two mast cell-mediated reactions induced by immunologic and nonimmunologic stimuli: immediate cutaneous reaction (icr) and acute bronchoconst ... | 1992 | 1383185 |
| type i allergy in the inner ear of the guinea pig. | guinea pigs were passively sensitized by sera containing antidinitrophenyl reaginic antibody and specifically challenged by dinitrophenyl-bovine serum albumin injected through the stylomastoid foramen. nystagmus, head deviation, negative summating potentials on electrocochleography, and an increase of threshold and wave i peak latency on auditory brain stem response testing were observed after local challenge. these physiologic changes were reversible and resolved within several days. we also us ... | 1992 | 1384414 |
| sedimentation in parasitological coproscopy. | a sedimentation technique is described, in which a fecal suspension is placed on top of an aqueous sucrose solution of specific gravity 1.015 g/cm3. using 100 by 15 mm test tubes, duplicate gravity sedimentation experiments were made using homogenized fecal suspensions (single-columns) and fecal suspensions placed on top of clear columns (double-columns). egg and cyst counts, and turbidity determinations were made in the sediments obtained after definite time intervals. most ascaris lumbricoides ... | 1992 | 1342080 |
| [anemia in a population from an endemic area of malaria, rondônia (brazil)]. | with the purpose of describing the prevalence rate of anaemia among inhabitants of a malaria endemic area--candeias district, a periurban locality near porto velho, in rondônia state, brazilian amazon basin--a random population sample comprehending 1,068 individuals of all age groups (14.1% of the total population) was screened for anaemia (measurement of blood haemoglobin concentration) and malaria (giemsa-stained thick-smear microscopy). two-hundred and ninety-nine individuals (28.0% of the sa ... | 1992 | 1342496 |
| effect of purified components of ascaris suum extracts on ige antibody response in guinea pigs. | the effect of components p530 and p29, isolated from ascaris suum adult worm extract (asc), on the heterologous ige antibody response was studied in guinea pigs. groups of 7 guinea pigs were immunized ip with 50 micrograms of ovalbumin (oa) alone or mixed with 200 micrograms of each component precipitated in an alum gel. the primary and secondary ige antibody response was evaluated by passive cutaneous anaphylaxis reaction (pca). immunization of guinea pigs with p29 plus ovalbumin (oa) resulted ... | 1992 | 1342594 |
| intensity of reinfection with ascaris lumbricoides and its implications for parasite control. | intestinal helminths are among the most common and widespread of human infections. because it is typical to find that most worms are aggregated in a few potential hosts it has been suggested that some individuals are predisposed to heavy infections and that morbidity could be controlled by the treatment of heavily infected individuals only. we have studied the prevalence and intensity of reinfection with the intestinal nematode ascaris lumbricoides among people living in dhaka, bangladesh. 880 p ... | 1992 | 1349668 |
| hookworm infection among the melka sedi banana plantation residents, middle awash valley, ethiopia. | a study of intestinal parasites was done among the people who lived within the banana plantation zone of the melka sedi agricultural enterprise, awash valley, ethiopia in april 1987. the methods of parasite detection were the ritchie formal ether and the charcoal culture method for hookworm larvae species identification. from the total 633 population, 311 were examined at random of whom 60.8% were positive for one or more intestinal parasites. eight parasites were encountered, ascaris lumbricoid ... | 1992 | 1396614 |
| [pruritus and eosinophilia in a native from equatorial guinea]. | | 1992 | 1489797 |
| detection of circulating antigens in human trichinellosis. | a 'sandwich' enzyme-linked immunosorbent assay was established to detect circulating antigens of trichinella spiralis in human sera, its sensitivity and specificity was evaluated using 4 antigens (trichinella spiralis, trichuris trichiura, dirofilaria immitis and ascaris suum), and it was found to be sensitive and specific for t. spiralis antigen. samples of 347 individuals with suspected trichinellosis, who had eaten incompletely cooked bear meat containing larvae of t. spiralis, were examined. ... | 1992 | 1412659 |
| identification of a novel 5-htn (nematoda) receptor from ascaris suum muscle. | 1. the abilities of various serotonergic drugs to bind with the 5-ht receptor of ascaris suum muscle and to affect cyclic amp levels in muscle tissue were examined. 2. ligands which selectively interact with either the 5-ht1 or the 5-ht2 receptor in mammalian systems interact with the 5-ht receptor from a. suum muscle and increase cyclic amp levels. 3. no binding of 5-ht3 ligands to 5-ht receptors from a. suum muscle was observed. 4. the 5-ht receptor of a. suum muscle should be called the 5-htn ... | 1992 | 1354123 |
| studies on the anti-allergic mechanism of glucocorticoids in mice. | glucocorticoids inhibit ige antibody-mediated passive cutaneous anaphylaxis (pca) and chemical mediator-induced cutaneous reactions elicited in the mouse ear. in the present study, we investigated the effect of actinomycin d, a protein synthesis inhibitor, on dexamethasone-caused inhibition of pca and histamine-induced cutaneous reaction in the mouse ear. tyrosine aminotransferase (tat) activity in the liver, which was estimated as an index for protein synthesis, significantly increased by the a ... | 1992 | 1362968 |
| the pyruvate dehydrogenase complex from the parasitic nematode ascaris suum: novel subunit composition and domain structure of the dihydrolipoyl transacetylase component. | the pyruvate dehydrogenase complex (pdc) from muscle of the adult parasitic nematode ascaris suum plays a unique role in its anaerobic mitochondrial metabolism. resolution of the intact complex in high salt dissociates the pyruvate dehydrogenase subunit but leaves the dihydrolipoyl dehydrogenase subunit (e3) and two other proteins with apparent m(r)s of 45 and 43 kda bound to the dihydrolipoyl transacetylase (e2) core. these proteins are not observable on coomassie brilliant blue-stained gels of ... | 1992 | 1376597 |
| oesophageal replacement in paediatric patients. | over a 5-year period from january 1986 to december 1990, 24 children aged between 16 months and 12 years with undilatable oesophageal stricture had oesophageal replacement with isoperistaltic colonic conduit. all the strictures followed accidental corrosive burns. the procedure was well tolerated; all the patients were able to swallow within 3 weeks of surgery. major postoperative complications were threatening pneumothorax (two cases), gastric outlet obstruction due to ascaris lumbricoides (two ... | 1992 | 1377242 |
| mechanism of action of my-1250, an active metabolite of repirinast, in inhibiting histamine release from rat mast cells. | 1. when my-1250 (3.6 x 10(-5) m) was added to mast cells, it caused a rapid increase in adenosine 3':5'-cyclic monophosphate (cyclic amp) and decrease in adenosine 5'-triphosphate (atp), both of which recovered to their original levels within 2 min. the accumulation of cyclic amp was maximal at 20 s after challenge with my-1250. the minimum level of atp was observed at 20 s after addition of my-1250. 2. the initial rise in [ca2+]i and the histamine release induced by dnp-as antigen (40 microgram ... | 1992 | 1378339 |
| immunoreactivity to two specific regions of chromogranin a in the nervous system of ascaris suum: an immunocytochemical study. | antisera to a highly conserved region of chromogranin a (sequence keltae) and to a hexapeptide (sequence kgqele) adjacent to the putative c-terminus of pancreastatin, a peptide whose sequence is found within the chromogranin a molecule, have been used to examine the localisation of immunoreactivity (ir) to these peptides in ascaris suum. ir to both peptides was found in the nerve rings and nerve cords. in addition, kgqele-ir was also observed in the pharyngeal neurones and in a network of fibres ... | 1992 | 1409533 |
| development of an animal model of late asthmatic response in guinea pigs and effects of anti-asthmatic drugs. | we developed an animal model of late asthmatic response (lar) in guinea pigs and examined the effects of anti-asthmatic drugs and peptide leukotriene antagonist, mci-826, on this model. bronchial challenge of dnp-as (dinitrophenylated-ascaris suum extract)-sensitized guinea pigs induced a biphasic increase in pulmonary resistance (rl) with the maximal increase being observed immediately (iar, immediate asthmatic response) and 3 to 5 hr after antigen inhalation (lar). twelve of 22 guinea pigs sho ... | 1992 | 1410517 |
| the primary structure of te-6: a novel neuropeptide from the nematode ascaris suum. | extensive immunoreactivity (ir) towards a hexapeptide (sequence kgqele), which flanks the c-terminus of the pancreastatin sequence in rat chromogranin a (cga), is found throughout the nervous system of the nematode parasite ascaris suum. the peptide ir was purified from the gonoduct of the parasite and found to have the sequence tkqele. this peptide, designated te-6, has some c-terminal homology with several regions of the cga molecule. however, te-6 was the only peptide isolated suggesting that ... | 1992 | 1417808 |
| predisposition to reinfection by intestinal helminths after chemotherapy in south thailand. | rates of reinfection by the intestinal helminths hookworm, ascaris lumbricoides and trichuris trichiura after chemotherapy were studied in two villages in phang-nga province, southern thailand. it was found that intensity of infection levels attained after reinfection correlated positively with pretreatment intensities of infection for all parasites. this implies that certain persons in the community are predisposed to receiving high numbers of worms, due either to environmental or personal risk ... | 1992 | 1428513 |
| [intestinal ascariasis. a rare cause of obstruction of the small intestine]. | ascariasis is a benign and common disease in tropical areas. due to its endemicity and high prevalence, serious abdominal complications requiring urgent and versatile surgical therapy do occur. an observation of intestinal obstruction by ascaris bundle, diagnosed during operation, is reported. the postoperative course was uneventful. | 1992 | 1429923 |
| [a survey of intestinal parasites of the foreign laborers (indonesians and filipinos) in ishikawa prefecture]. | a survey of intestinal parasites was conducted on 198 foreign workers aged 19-27 from inodonesia and philippines. they work for a private company in ishikawa prefecture as technical trainee. on the base of stool examination, 94 (71%) out of 133 indonesians and 48 (74%) of 65 filipinos had intestinal helminths and/or protozoan infections. the prevalence of ascaris lumbricoides, trichuris trichura and hookworm was 4.5, 64.1, 10.6%, respectively. in addition, the positive rate of the cyst of entamo ... | 1992 | 1431385 |
| granulomatous peritonitis by ascaris. | the granulomatous peritonitis by ascaris (gpa) is a rare complication of intestinal ascariasis due to the perforation of the digestive tract by the adult worm, which deposits its ova in free peritoneum; therefore, provoking an intense granulomatous inflammatory reaction. we report a case of an 8-year-old boy with gpa, emphasizing the clinical and diagnostical aspects and the therapeutics procedures. | 1992 | 1432537 |
| interaction between ascaris suum and pasteurella multocida in the lungs of mice. | in an experiment including 8 groups of 15 mice, the effect of migrating ascaris suum larvae in the lungs on the establishment and pathogenicity of aerosol exposure to pasteurella multocida was investigated. following aerosol exposure to p. multocida, mice with migrating a. suum in their lungs developed more severe pneumonia and septicaemia than did parasite-free mice. the parasite-induced effect on bacterial pathogenicity was more marked for a non-toxin-producing p. multocida as compared with a ... | 1992 | 1438140 |
| intestinal parasitic infections in likupang, north sulawesi, indonesia. | a parasitological survey was conducted on the inhabitants of 6 villages of likupang, minahasa peninsula, north sulawesi, indonesia, in august 1991. a total of 419 fecal samples were examined by using direct smear, flotation, formalin ether concentration, harada-mori culture and agar-plate culture techniques. five nematode and 7 protozoan parasites were detected, while trematode and cestode infection was not observed. soil-transmitted nematode infections were predominant. among the younger inhabi ... | 1992 | 1439973 |
| mechanism of activation of the nad-malic enzyme from ascaris suum by fumarate. | the mechanism of activation of the nad-malic enzyme from ascaris suum by fumarate has been probed using initial velocity studies, deuterium isotope effects, and isotope partitioning of the e:mg:malate complex. fumarate exerts its activating effect by decreasing the off-rate for malate from the e:mg:malate and e:nad:mg:malate complexes. fumarate is a positive heterotropic effector of the nad-malic enzyme at low concentrations (k act approximately 0.05 mm) and an inhibitor competitive against mala ... | 1992 | 1444459 |
| ascaris hemoglobin gene: plant-like structure reflects the ancestral globin gene. | animal globin genes have two introns at strictly conserved positions, while plant globin genes have both of these as well as an additional, central intron. it has been proposed that a common ancestor gene had three introns, one of which was subsequently lost from animal but not plant globin genes. we have elucidated the cdna sequence and gene structure of a hemoglobin from the parasitic nematode ascaris suum and found a plant-like central intron, providing strong evidence for a three-intron ance ... | 1992 | 1465385 |
| components of sterol biosynthesis assembled on the oxygen-avid hemoglobin of ascaris. | the parasitic nematode ascaris infests a billion people worldwide. much of its proliferative success is due to prodigious egg production, up to 10(6) sterol-replete eggs per day. sterol synthesis requires molecular oxygen for squalene epoxidation, yet oxygen is scarce in the intestinal folds the worms inhabit. ascaris has an oxygen-avid hemoglobin in the perienteric fluid that bathes its reproductive organs. purified hemoglobin contained tightly bound squalene and functioned as an nadph-dependen ... | 1992 | 1470914 |
| an extremely abundant ovarian mrna from the parasitic nematode ascaris lumbricoides var. suum has multiple repeat motifs. | | 1992 | 1474996 |
| 5-lipoxygenase inhibitors and their anti-inflammatory activities. | a wide variety of agents have been reported as 5-lo inhibitors. the majority of the series appear to be lipophilic reducing agents, including phenols, partially saturated aromatics, and compounds containing heteroatom-heteroatom bonds. many of these are not selective 5-lo inhibitors, but often affect co and other los as well. in vivo systemic activity for many of these has been, in general, disappointing, probably because of poor bioavailability caused by lipophilicity and metabolic instability ... | 1992 | 1475368 |
| serologic findings in hepatic ascariasis: a case report. | a 56-year-old japanese woman underwent partial hepatectomy for intrahepatic cystic masses. before operation, the patient had been diagnosed as liver abscess due to ascaris infection serologically. the excised hepatic lesions consisted of encapsulated old abscesses, with a few calcified parasitic ova and numerous charcot-leiden's crystals microscopically seen in necrotic exudate. however, no parasitic worms were found in the cystic cavity. the eggs in the tissues were indistinguishable from other ... | 1992 | 1475784 |
| intestinal parasites in zambian patients with aids. | previous studies have found a high prevalence of isospora belli and cryptosporidium parvum infections in african acquired immune deficiency syndrome (aids) patients with chronic diarrhoea. we aimed to determine the prevalence of gastrointestinal parasite in aids patients in hospital, not only those with diarrhoea, and to compare them with the general community. clinically diagnosed aids patients in a zambian teaching hospital were interviewed and examined, and stool specimens were studied for pa ... | 1992 | 1475829 |
| ascaris-induced acute pancreatitis. | the incidence, clinical disease and outcome of acute pancreatitis caused by ascariasis in an endemic area of kashmir, india, was studied prospectively. ascariasis was an aetiological factor in 59 of 256 patients (23.0 per cent) with acute pancreatitis. worms had invaded the bile duct in 51 patients, the pancreatic duct in four and both ducts in four. pancreatitis was mild in 46 patients and severe in 13. associated pyogenic cholangitis was present in eight. acute complications occurred in 11 pat ... | 1992 | 1486433 |
| [the effect of ascaris lumbricoides suis and its trypsin inhibitor on the chick embryo]. | it has been found that tegument homogenate of ascaris lumbricoides suis and also trypsin inhibitor isolated from it induce the leghorn chick embryos mortality when injected into their yolk sac on 4th, 8th or 13th day of incubation. the trypsin inhibitor is one of important components of ascaris homogenate causing mortality. there is linear interrelationship between the logarithm of dose of homogenate or trypsin inhibitor and the mortality of chickens in %. a significant decrease of mean mass of ... | 1992 | 1488839 |
| chromatin diminution in nematode development. | chromatin diminution in parascaris and ascaris represents the classical case of a developmentally programmed genome rearrangement. the process is very specific with respect to ontogenetic timing and chromosomal localization, and involves chromosomal breakage, new telomere formation and dna degradation. recent evidence from ascaris lumbricoides var. suum suggests that chromatin diminution might have a function in gene regulation. | 1992 | 1492368 |
| ascaris suum--vaccination of mice with liposome encapsulated antigen. | vaccination with liposome encapsulated adult crude antigen with and without coencapsulated immunomodulator (levamisole) in a mice/larval ascaris suum model provided protection against a challenge infection (2000 eggs) in mice immunised by immobilised antigen. the best results (88.9% protection) were obtained with a combination of two doses of liposome entrapped antigen with leamisole. vaccination with liposome vaccine without modulator was slightly less effective (78.7% protection). a single dos ... | 1992 | 1496793 |
| association of a heat-stable inhibitor protein with cyclic-3',5'-amp-dependent protein kinase from the nematode ascaris suum: purification and characterization of the inhibitor. | an inhibitor protein of the catalytic subunit of the cyclic 3',5'-amp-dependent protein kinase from the nematode ascaris suum was isolated and characterized. the molecular weight of the inhibitor was estimated as 28,000 by electrophoresis under denaturing conditions and as 30,000 by gel permeation chromatography on superose 12. the trypsin-labile inhibitor was resistant to short incubations (less than or equal to 5 min) at temperatures up to 95 degrees c and at ph 3. it affected the protein kina ... | 1992 | 1497350 |
| mechanisms of microenvironmental ph regulation in the cuticle of ascaris suum. | the excretion kinetics of various organic acids by ascaris suum were quantified to determine if the excretion of these metabolic end-products could generate and maintain a microclimate ph within the aqueous compartment of the cuticle. ligated and nonligated a. suum were incubated in media buffered with 0.25 or 2.5 mm hepes (initial ph 7.5) or 0.5 or 5 mm glycine (initial ph 3.25). the concentration of organic acids and the ph of the media were followed for 24 h. several volatile fatty acids, inc ... | 1992 | 1501633 |
| hepatic lesions caused by excretory and secretory products of ascaris lumbricoides in golden hamster. | to ascertain the role of excretory and secretory (es) products of ascaris lumbricoides in liver damage. | 1992 | 1506046 |
| [ascaris lumbricoides--a cause of acute abdomen]. | ascaris lumbricoides infestation is the most common helminthic disease in many developing countries and may cause severe surgical complications, especially in children. we present a 3-year-old ethiopian immigrant brought to hospital directly from the airport because of signs of acute abdomen. it was found to be caused by volvulus and necrosis of a loop of bowel impacted with worms. the necrotic bowel loop was resected and a temporary ileostomy was formed; recovery was uneventful. this disease an ... | 1992 | 1516872 |
| molecular characterization of a dirofilaria immitis cdna encoding a highly immunoreactive antigen. | dirofilaria immitis, a filarial nematode, is the causative agent of canine and feline heartworm disease. previous research has demonstrated that immunity to d. immitis can be induced in dogs by repeated chemical abbreviation of infections while the parasite is a fourth-stage larva. sera obtained from dogs immunized in this manner has been effective in passively transferring larval killing and stunting. these immune sera, by comparison to nonimmune sera from infected cohorts, recognize a number o ... | 1992 | 1518532 |
| structure and macromolecular assembly of two isoforms of the major sperm protein (msp) from the amoeboid sperm of the nematode, ascaris suum. | ascaris sperm are amoeboid cells that crawl by extending pseudopods. although amoeboid motility is generally mediated through an actin-based cytoskeleton, ascaris sperm lack this system. instead, their major sperm protein (msp) forms an extensive filament system that appears to fulfil this function. because their motility appears to be essentially the same as that of their actin-rich counterparts, ascaris sperm offer a simple alternative system for investigation of the molecular mechanism of amo ... | 1992 | 1527183 |
| resistance to ascaris suum in parasite naïve and naturally exposed growers, finishers and sows. | commercially reared growers, finishers, and sows of danish landrace x yorkshire crossbred were inoculated orally with ascaris suum at 50 eggs kg-1 body weight. white spots on the serosal surface of livers and total larval recoveries from lungs were recorded 7 days later. the response in pigs originating from a specific pathogen free and parasite free herd (parasite naïve) was observed in the three different age groups and compared with age-matched pigs from a herd maintained in a facility contam ... | 1992 | 1532874 |
| response to repeated inoculations with ascaris suum eggs in pigs during the fattening period. i. studies on worm population kinetics. | this experimental study on pigs was designed to simulate natural, long-term exposure to ascaris suum under modern management conditions. parasite kinetics were followed in pigs receiving a. suum eggs as repeated trickle inoculations at two dose levels beginning at a body weight of 25 kg until their slaughter at 90 kg (baconers). in pigs inoculated twice weekly with 500 eggs, there was an initial marked rise in the numbers of hepatic milk spots, but as early as around week 6 after the start of in ... | 1992 | 1534170 |
| influence of intestinal parasitism on lactose absorption in well-nourished african children. | hydrogen breath tests were performed in gabon (central africa) after a loading dose of lactose in 67 well-nourished african children (50 with intestinal parasites and 17 unparasitized) and in 18 unparasitized young adults. all had normal nutritional status, and none had diarrhea or digestive symptoms. parasites that were found included ascaris lumbricoides in 76% of the parasitized children, trichuris trichiura in 58%, giardia in 24%, entamoeba histolytica in 20%, schistosoma intercalatum in 16% ... | 1992 | 1539747 |
| mechanism of allergic cross-reactions--iii. cdna cloning and variable-region sequence analysis of two ige antibodies specific for trinitrophenyl. | as a first step toward defining the molecular interactions between ligands and the ige antigen-combining site, we report here the cdna cloning and variable (v) region nucleic acid sequences of the heavy (h) and light (l) chains of 2 monoclonal mouse ige antibodies to trinitrophenyl (atcc-tib142 = igela2 and atcc-tib141 = igelb4). in all instances, full-length cdna clones were obtained to facilitate future expression studies. the h chains were encoded by vh genes from the vh3660 and j558 gene fam ... | 1992 | 1542295 |