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diagnosis of plasmodium malariae infection by the polymerase chain reaction. 19979373635
[imported malaria in children in 1999. study of the armand-trousseau hospital in paris].eighty children were treated at the hospital armand-trousseau (paris, france) for a malaria attack from 1999-01-01 to 2000-02-01.200211998422
unusual plasmodium malariae-like parasites in southeast asia.during malaria surveys in myanmar, 2 peculiar forms of plasmodium malariae-like parasites were found. the morphologies of their early trophozoite stages were distinct from that of the typical p. malariae, resembling instead that of plasmodium vivax, var. minuta, reported by emin, and plasmodium tenue, reported by stephens, both in 1914. two polymerase chain reaction (pcr)-based diagnoses, which target the same regions in the small subunit ribosomal rna (ssurrna) genes, indicated that these paras ...200212054010
transmission of mixed malaria species and strains by mosquitoes, as detected by pcr, in a study area in guinea-bissau.parasites present in blood samples of asymptomatic carriers and in the midgut of mosquitoes collected within a few days from the same households, have been analysed by pcr. a high prevalence (32%) of infected mosquitoes was observed and, in half of these, two parasite species were found simultaneously. the distribution of parasite species in the mosquito correlated with that found in the infected persons. genotype patterns of plasmodium falciparum populations were however found to be different i ...19979419850
[malaria surveys in a humid savannah region in côte d'ivoire].the purpose of this report is to describe six surveys carried out from march 1993 to march 1994 to assess seasonal variations in parasite indexes and malaria morbidity rates in children between the ages of 0 and 14 years living in the village of alloukoukro in the wet savannah region of cote d'ivoire. results demonstrated the presence of both plasmodium falciparum and plasmodium malariae. no case of infection only by plasmodium malriae was observed. parasite indexes were greater than 50% in all ...19989718556
malaria epidemiology, glucose 6-phosphate dehydrogenase deficiency and human settlement in the vanuatu archipelago.vanuatu is located at the southeast margin of the malarious band extending from southeast asia to eastern melanesia. we analysed the malaria situation on different islands of vanuatu, using passive case detection and malariometric survey data from 1985 to 1992, i.e. after the ddt residual programme ceased and before the impregnated bed-nets programme started on a larger scale. malaria was mainly hypo-mesoendemic but with hyperendemic spots in certain years and on some islands. the transmission w ...19989777715
[prevalence of malaria in the senegal river basin in 1991].in order to determine the prevalence of malaria and its epidemiological characteristics, a survey was carried out in 11 villages situated in all the basin of river senegal (b.r.s.). 3306 (0-14 years) children are examined. the results show that malaria is hypo-endemic in the b.r.s. with a plasmodic index of 8.6% and a splenic index of 9.9%. but these malariametric indexes change according to the areas visited. thus, malaria prevails at a hypo-endemic level in dagana and podor districts while at ...19979827125
[two cases of mixed infection of malaria diagnosed by pcr method].we here reported two japanese cases of mixed infections of plasmodium species, whose dnas were detected using the pcr test. one case was a 31 year-old male, who presented fever and fatigue, and had a travel history to kenya, cameroon and indonesia. smear test of his peripheral blood found the presence of plasmodium vivax, while nested-pcr diagnosis detected the dnas both p. vivax and plasmodium malariae. the other was a 54 year-old female suffering from general fatigue. she had been treated with ...200212212325
[current data on malaria in metropolitan france].epidemiological data from the french national reference center for imported diseases showed that the estimated number of cases of imported malaria in france increased from 5,940 in 1998 to 7,127 in 1999 and 8,056 in 2000. this three-year progression ended in 2001 when the number of estimated cases fell back to 7,223. it was due mainly to the concomitant increase in the number of people traveling to endemic zones especially in africa. in 2000 the median age of patients with imported malaria in fr ...200212244913
virus safety of human blood, plasma, and derived products.the reconstitution of blood and its components is hampered by factors of compatibility, availability, and the risk of transmission of infectious diseases. protozoal agents such as plasmodium malariae and trypanosoma cruzi are only regionally relevant. bacterial transmissions are easy to prevent and treat. antibody, antigen, and nucleic acid screening have been implemented to prevent transmission of blood-borne viruses. transfusion-relevant viruses include hepatitis b and c virus (hbv and hcv), h ...200212379292
evidence for the efficacy of artesunate in asymptomatic plasmodium malariae infections.this study evaluated the efficacy and safety of a 3-day course of artesunate (4 mg/kg/day) for asymptomatic plasmodium malariae infections. the parasitological cure rates on days 7 and 56 in the group treated with artesunate were 100% and 83%, respectively, compared with no cure in the placebo group (p < 0.0001).200212407136
extended clearance time after treatment of infections with plasmodium malariae may not be indicative of resistance to chloroquine.a retrospective examination was made of archival data on the response of plasmodium malariae infections in humans to chloroquine. the clearance time for p. malariae was longer than that for p. falciparum and p. vivax. of 100 p. malariae-infected patients treated with 1,500 mg of chloroquine given over 3 days, 15 had detectable parasites for 7 days, 4 for 10 days, and 1 for 15 days after treatment. of 17 patients treated intramuscularly with 450 mg of dihydrochloroquine, parasites persisted in 1 ...200212452495
plasmodium malariae infection boosts plasmodium falciparum gametocyte production.we analyzed records of malaria therapy patients sequentially or simultaneously inoculated with plasmodium falciparum and plasmodium malariae. gametocyte production was enhanced in p. falciparum by prior or concurrent p. malariae infection but diminished or unaffected in p. malariae by p. falciparum. conversely, asexual-form production was diminished in p. malariae but unaffected in p. falciparum.200212452496
rapid immunochromatographic malarial antigen detection unreliable for detecting plasmodium malariae and plasmodium ovale.in order to determine the reliability of two commercial tests for the rapid detection of plasmodial antigen in cases of infection with plasmodium ovale and plasmodium malariae, the products were evaluated in four centers and a search of the relevant literature was performed. the results of the present and previous studies were compared. with overall sensitivities ranging between 18.8% and 47.6% for plasmodium malariae and between 20% and 31.3% for plasmodium ovale, it is evident that neither tes ...200212461593
[important parasitic nephropathies: update from the recent literature].renal involvement in parasitic infections are polymorphic. plasmodium malariae often leads to membranoproliferative glomerulonephritis whereas acute tubular necrosis or post-infectious acute glomerulonephritis are observed with plasmodium falciparum. urogenital taxis of schistosoma haematobium is responsible for frequency of chronic tubular and interstitial nephritis. without specific treatment, the renal function progressively deteriorates and urological complications appear. schistosoma manson ...199910227026
[treatment of malaria in children: 1. uncomplicated malaria].malaria is a worldwide epidemic causing high morbidity and mortality especially in children younger than 5 years. in france the incidence of pediatric malaria has constantly increased up to 1500 cases in the last two years, due to plasmodium falciparum in more than 80% of cases. according to current recommendations, any patient with clinical suspicion or confirmed diagnosis of malaria must be hospitalized for treatment. halofantrine is the most widely used antimalarial for treatment of uncomplic ...200212616950
transmission of mixed plasmodium species and plasmodium falciparum genotypes.we studied malaria transmission by comparing parasite populations in humans and mosquito vectors at the household level. blood samples were collected from all inhabitants for microscopic detection of gametocytes and polymerase chain reaction analysis. the next morning, blood-fed resting mosquitoes were collected inside the bed nets used by the individuals surveyed the previous afternoon. after 8 days of maintenance, mosquitoes were dissected, and midguts and salivary glands were recovered for po ...200312641406
automated detection of malaria-associated intraleucocytic haemozoin by cell-dyn cd4000 depolarization analysis.laboratory tests for malaria are only performed if there is clinical suspicion of the disease, and a missed diagnosis contributes substantially to morbidity and mortality. malaria parasites produce haemozoin, which is able to depolarize light and this allows the automated detection of malaria during routine complete blood count analysis (cbc) with some abbott cell-dyn instruments. in this study, we evaluated the cell-dyn cd4000 with 831 blood samples submitted for malaria investigations. samples ...200312641610
a retrospective examination of sporozoite- and trophozoite-induced infections with plasmodium falciparum in patients previously infected with heterologous species of plasmodium: effect on development of parasitologic and clinical immunity.a retrospective examination was made to determine parasitemia and episodes of fever in 97 patients, previously infected with plasmodium malariae, p. ovale, and/or p. vivax, who were reinfected with p. falciparum for treatment of neurosyphilis, the standard treatment at the time. data were collected at the national institutes of health laboratories in columbia, south carolina and milledgeville, georgia during the period 1940 to 1963. results were compared with observations recorded for patients f ...199910432043
malaria in austria 1990-2000.in austria, between 1990 and 2000, 924 travel related malaria cases were reported (mean = 84/year). no significant decreasing or increasing trends were observed. p. falciparum (n=517; 55.9%) accounted for the highest number of cases followed by p. vivax or ovale (n=321; 34.7%) and p. malariae (n=29; 2.2%). most infections were contracted in highly endemic malaria regions (n=686; 74.2%) and most cases were reported from the largest counties: vienna (n=336, 36.4%), styria (n=156, 16.8%), and lower ...200312764239
cross-species regulation of plasmodium parasitemia in semi-immune children from papua new guinea.malariologists have long been fascinated by the question of whether plasmodium spp. interact in the human host. the first genetic study of the longitudinal dynamics of multiple plasmodium spp. and genotypes in humans has been completed in papua new guinea, where all four plasmodium spp. that infect humans are present. the broad implications of the data from this study are covered here and they show that the total parasite density of plasmodium species oscillates around a threshold and that peaks ...200312798085
use of a rapid, single-round, multiplex pcr to detect malarial parasites and identify the species present.a new, rapid assay, based on a single-round, multiplex pcr, can be used to detect plasmodium falciparum, p. vivax, p. malariae or p. ovale in human blood. the pcr, which targets the conserved 18s small-subunit rna genes of the parasites, not only permits a malarial infection to be detected but also allows each plasmodium species present to be identified, even in cases of mixed infection.200312803868
evaluation of efficacy and safety of a herbal medicine used for the treatment of malaria.resistance of plasmodium falciparum to chloroquine has been reported in several countries. other anti-malarial drugs in use are expensive and not readily accessible to most people in malaria endemic countries. this has led to renewed interest in the development of herbal medicines that have the potential to treat malaria with little or no side effects. this study obtained a preliminary information on the safety and effectiveness of a plant decoction (am-1), used in treating malaria. the am-1 is ...200312820245
anopheles parensis: the main member of the anopheles funestus species group found resting inside human dwellings in mwea area of central kenya toward the end of the rainy season.a total of 460 anopheles funestus s.l. was collected inside human dwellings in mwea, central kenya. of the 414 specimens that were positively identified, 1 was anopheles leesoni and the others were anopheles parensis. none of the 373 specimens tested were positive for plasmodium falciparum or plasmodium malariae sporozoites by enzyme-linked immunosorbent assay (elisa). of the 139 elisa blood-meal-positive specimens, 82.01% and 1.44% had fed on cattle and humans, respectively. these results are d ...200312825663
[triple malaria infection in twin sisters from the democratic republic of congo].infections with 3 species of malaria parasites are rarely encountered and observed in less than 0.05% of cases. we came across such an infection in four year-old, monozygote twin sisters, coming from kinshasa (democratic republic of congo). in both of them, parasitemia was low or very low for p. falciparum and p. ovale and of 0.1-0.2% for p. malariae. the twin sisters presented with an iron deficiency anaemia, associated with an heterozygous sickle-cell anaemia and a moderate splenomegaly. the b ...200312836524
five cases of hiv with hms--but where are the rest? 200312837331
drug treatment of malaria in children. 200312867842
[incidence of plasmodium malariae in endemic malarial zone in somaliland; survey and epidemiologic study]. 195313101478
[double infection of an erythrocyte with plasmodium malariae]. 195413176557
preservation of viable human malaria sporozoites by low-temperature freezing. 195513262073
sterile microdissection and isolation of malarial oocysts. 195513267464
transmission of plasmodium malariae by laboratory-bred anopheles maculipennis var. atroparvus meigen. 195513283514
studies on the nature of malarial pigment (haemozoin). ii. the pigment of the human species, plasmodium falciparum and p. malariae. 195613340682
[studies of the duration of the course of plasmodium vivax, plasmodium falciparum and plasmodium malariae infections]. 195613396343
the response of plasmodium malariae infections to pyrimethamine (daraprim). 195713424896
resistance of plasmodium malariae to pyrimethamine (daraprim). 195713458666
notes on the characters of p. malariae oöcysts of possible value in mixed infections. 195713487968
[the mechanism of feeding of plasmodium malariae; electron-microscopic studies]. 195813604211
[morphological observations on various stages of plasmodium vivax and plasmodium malariae in blood preserved by refrigeration for transfusion]. 196113772462
the infectivity to mosquitoes of plasmodium malariae. 196113787476
pre-erythrocytic stages of human malaria parasites: plasmodium malariae. 195913804057
studies on malaria in chimpanzees. viii. the experimental transmission and pre-erythrocytic phase of plasmodium malariae, with a note on the host-range of the parasite. 196013804058
possible aetiological role of plasmodium malariae in "nephrotic syndrome" in nigerian children. 196013850078
how prevalent is plasmodium malariae in rondônia, western brazilian amazon?we have compared results of plasmodium species identification obtained with conventional on-site microscopy of giemsa-stained thick smears (gts) and a semi-nested polymerase chain reaction (pcr) in 96 malaria patients from rondônia, western brazilian amazon. mixed-species infections were detected by pcr in 30% patients, but no such case had been found on gts. moreover, p. malariae infections were detected in 9 of 96 patients (10%) by pcr, but were not identified by local microscopists. the poten ...200011064586
[use of fluorescence microscopic methods for the demonstration of malarial parasites]. 196213895679
nephrosis in nigerian children. role of plasmodium malariae, and effect of antimalarial treatment. 196313947894
studies on the distribution and transmission of malaria and filariasis among aborigines in malaya. 196314042655
plasmodium malariae in ugandan children. i. prevalence in young children in rural communities. 196314044737
plasmodium malariae in ugandan children. ii. malaria parasites in children at mulago hospital in kampala. 196314044738
a longitudinal survey of natural malaria infection in a group of west african adults. 196314056767
fluorescent antibody studies in human malaria.i. development of antibodies to plasmodium malariae. 196414106048
malaria distribution in tanganyika. iii. the south-east. 196414114651
[research on the infective capacity for a. atroparvus, of asymptomatic p. vivax, p. falciparum and p. malariae parasitemias]. 196414122437
age- and species-specific duration of infection in asymptomatic malaria infections in papua new guinea.the burden and duration of asymptomatic malaria infections were measured in residents of the malaria endemic village of gonoa, madang province, papua new guinea. plasmodium falciparum, p. vivax and p. malariae infections in people aged 4 years to adulthood were compared. frequent sampling at 3-day intervals for up to 61 days allowed assessment of individual episodes of infection. statistical assessment of p. falciparum detection revealed a periodicity consistent with synchronous replication of t ...200011085245
unfinished business. 196414125874
fluorescent antibody studies in human malaria. ii. development and persistence of antibodies to plasmodium falciparum. 196414125876
studies to determine the vectors of monkey malaria in malaya. 196414147666
the heparinized capillary tube as an epidemiologic tool. ii. concentration of blood parasites by centrifugation. 196414192772
[on the detection of plasmodium malariae in the sternal marrow]. 196414242786
idiopathic splenomegaly. 196514243068
[experimental studies on antimalarial properties of haloquine. ii. possibility of the development of haloquine resistance among malarial parasites]. 196514345036
studies on the mechanism of infection of the mosquito midgut by plasmodium gallinaceum. 196214449364
malaria clusters among illegal chinese immigrants to europe through africa.between november 2002 and march 2003, 17 cases of malaria (1 fatal) were observed in illegal chinese immigrants who traveled to italy through africa. a further cluster of 12 was reported in august, 2002. several immigrants traveled by air, making the risk of introducing sudden acute respiratory syndrome a possibility should such illegal immigrations continue.200314519261
performance of the optimal assay for detection and identification of malaria infections in asymptomatic residents of irian jaya, indonesia.the optimal assay, a new immunochromatographic "dipstick" test for malaria based on detection of plasmodium lactate dehydrogenase (pldh), is purported to detect infections of approximately 200 parasites/microl of blood and to differentiate between plasmodium falciparum and non-p. falciparum. we evaluated optimal performance by comparing the test strip interpretations of two independent readers with consensus results obtained independently by expert malaria microscopists. unbiased measures of sen ...200011388505
plasmepsin 4, the food vacuole aspartic proteinase found in all plasmodium spp. infecting man.plasmepsins are aspartic proteinases of the malaria parasite, and seven groups of plasmepsins have been identified by comparing genomic sequence data available for the genes encoding these enzymes from plasmodium falciparum, plasmodium vivax, plasmodium knowlesi, plasmodium berghei, and plasmodium yoelii. the food vacuole plasmepsins typified by plasmepsin 4 from p. falciparum (pfpm4) constitute one of these groups. genes encoding the ortholog of pfpm4 have been cloned from plasmodium ovale, pla ...200314550891
[malaria outside the brazilian amazonian region: the situation in santa catarina state].this study aimed to evaluate the malaria epidemiological aspects in santa catarina state, brazil, by using national health foundation data from 1996 to 2001. from 4,707 thick smears analyzed 5.5% were positive. plasmodium vivax was found in 69.0%; plasmodium falciparum in 25.6%, mixed infection with both in 5%, and plasmodium malariae in only 0.4%. it was observed that 67.4% were heterochthonous cases and 32.6% autochthonous cases. in recent years, the incidence of heterochthonous cases has incr ...200314576872
insecticide-treated curtains reduce the prevalence and intensity of malaria infection in burkina faso.a large, randomized controlled trial to investigate the impact of insecticide-treated curtains (itc) on child mortality was conducted in an area of seasonal, holoendemic malaria in burkina faso. 158 communities totalling some 90,000 people were censused and grouped into 16 geographical clusters, 8 of which were randomly selected to receive itc in june-july 1994, just prior to the rainy season. in september-october 1995, at the peak period of malaria transmission, a cross-sectional survey was con ...199910499079
igg reactivities against recombinant rhoptry-associated protein-1 (rrap-1) are associated with mixed plasmodium infections and protection against disease in tanzanian children.a cross-sectional sero-epidemiological study was performed in magoda, tanzania, an area where malaria is holoendemic. blood samples were collected from children (1-4 years) and tested for igg antibody reactivity against 2 recombinant protein fragments of plasmodium falciparum rhoptry-associated protein-1 (rrap-1). the data were related to the prevalence of malarial disease and single p. falciparum or mixed plasmodium infections. fever (> or = 37.5 degrees c) in combination with parasite densitie ...199910581610
cross-species interactions between malaria parasites in humans.the dynamics of multiple plasmodium infections in asymptomatic children living under intense malaria transmission pressure provide evidence for a density-dependent regulation that transcends species as well as genotype. this regulation, in combination with species- and genotype-specific immune responses, results in nonindependent, sequential episodes of infection with each species.200010657296
re-emergence of plasmodium malariae in trinidad, west indies.a focus of plasmodium malariae infection has recently occurred on the island of trinidad, some 30 years after a successful eradication programme. examination of bloodsmears revealed 22 cases of p. malariae in the nariva-mayaro area of trinidad between august 1994 and september 1995. most (77%) of the cases were male and, as seven were aged < 25 years of age, it appeared that transmission had been renewed, probably by the vector anopheles bellator. however, none of the 3000 mosquitoes tested by e ...199910690242
monkeys of the rainforest in french guiana are natural reservoirs for p. brasilianum/p. malariae malaria.monkey blood samples were collected from 214 monkeys relocated as part of the wildlife rescue organized in french guiana during the filling of the petit saut dam on the sinnamary river. these samples were tested for malaria parasites by microscopy of thick blood filsm and by nested pcr for small subunit rrna genes (ssurrna). parasitic blood forms similar to plasmodium brasilianum were detected in 4 monkey species: alouatta seniculus macconnelli, saguinus midas midas, pithecia pithecia and ateles ...200010726261
malaria infections in japan. 199910808257
[congenital malaria due to plasmodium falciparum and plasmodium malariae].increasing tourism and growing numbers of immigrants from malaria-endemic countries are leading to a higher importation rate of rare tropical disorders in european countries. we describe, to the best of our knowledge, the first case of connatal malaria in austria. the patient is the first child of a 24 year old mother who was born in ghana and immigrated to austria one and a half years before delivery. she did not stay in an endemic region during this period and did not show fever or any other s ...200010890139
[the malaria situation in turkey].turkey is the last country in the temperate zone on the edge of the european continent in which malaria is prevalent at endemic and occasionally epidemic proportions. malaria was the most significant vector borne disease constituting a serious healthy problem until it was suppressed in 1965. following the establishment of malaria eradication program in 1957 which began operation in 1960 after many years of malaria control, the incidence of malaria decreased annually and the stricken areas became ...200010900916
frequent umbilical cord-blood and maternal-blood infections with plasmodium falciparum, p. malariae, and p. ovale in kenya.the prevalence of malaria infection in 102 paired maternal-blood and umbilical cord-blood samples was assessed by microscopy and polymerase chain reaction (pcr) in a holoendemic area in kenya. plasmodium falciparum single-species infection was detected in maternal peripheral blood (3.4%), whereas microscopy indicated that no plasmodium species were in cord blood. in contrast, maternal-blood samples showed a pcr prevalence of 48% for p. falciparum, 25% for p. malariae, and 24% for p. ovale, and c ...200010915089
malarial acute renal failure. 200011053494
the history of italian parasitology.the history of italian parasitology can be subdivided into two periods: pre-redi and post-redi. the first period includes the contributions to parasitology by savants who operated during the roman, medieval and renaissance eras; the second period started in 1668 when francesco redi published his experiments to debunk the theory of spontaneous generation; the work of redi was subsequently continued by vallisnieri, spallanzani and others. the latter period includes classic contributions in the fie ...200111516576
[evaluation of the optimal test in the diagnosis of imported malarial outbreak].the optimal test is an immuno-chromatographic dipstick test that permits indiscriminate detection of plasmodium falciparum and other species of human malaria. the purpose of this study was to evaluate the efficacy of the test for diagnosis of imported malaria. a total of 244 patients with a presumptive diagnosis of imported malaria in france were included during the study period. the reference test, i.e., combined thick and thin blood films, demonstrated infection by plasmodium falciparum in 58 ...200111582872
[unusual case of malaria in italy].there is a significant increase in cases of malaria in italy. the incidence among italian citizens has remained quite stable since 1990, while the number of cases among foreigners residing in italy has continued to increase. the clinical manifestations of plasmodium infection can be less evident in these people: they often have only mild complaints for weeks or months. the case of a senegalese woman with plasmodium malariae infection is presented. she had been in italy for 13 months and was 4-mo ...200111799633
congenital malaria as a result of plasmodium malariae--north carolina, 2000.congenitally acquired malaria is rare in the united states; < or = 10 cases are reported each year. congenital infection with plasmodium malariae is particularly uncommon because distribution of this parasite is focal and sparse in areas where p. falciparum is endemic. the last case of congenital p. malariae infection in the united states was reported in 1992. this report describes the investigation of a case of p. malariae in an infant with no travel history outside of the united states and sug ...200211900117
from the centers for disease control and prevention. congenital malaria as a results of plasmodium malariae--north carolina, 2000. 200211917921
chloroquine-resistant plasmodium malariae in south sumatra, indonesia.oral chloroquine is the treatment of choice for uncomplicated plasmodium malariae infections worldwide. we did a prospective 28-day in-vivo assessment of the efficacy of chloroquine for treatment of p malariae on legundi island in lampung bay, sumatra, indonesia. of 28 patients, one had recurrent parasitaemia on day 28, and two had persistent parasitaemia to day 8. whole-blood chloroquine and desethylchloroquine concentrations were at ordinarily effective levels (> or = 100 microg/l) on day 8 in ...200212114045
molecular characterisation of airport malaria: four cases in france during summer 1999.four airport malaria cases have been observed in the vicinity of the roissy-charles-de-gaulle international airport, paris, france. these cases were geographically very close to each other and clustered in a short period of time during the summer of 1999. the phenotype and genotype of the plasmodium falciparum isolates obtained from these patients were determined in order to know whether a single mosquito could have infected more than one subject. the genomic characterisation of isolates was per ...200212116866
[the epidemiology of malaria in the southwestern forests of the ivory coast (tai region)].an epidemiological study on malaria was undertaken between july 1995 and july 1996 in two villages (zaïpobly and gahably) and their encampments (kouassikro, hamanikro and konankro), in the south-western forest area of côte d'ivoire (region of taï). the parasitological scheme comprised a total of 2023 tests performed on children aged from 0 to 14 years. the species found were plasmodium falciparum, p. malariae and p. ovale with a proportion of 84%, 14% and 2% respectively. the global parasite pre ...200212145967
chloroquine for the treatment of uncomplicated malaria in guyana.at a public hospital in georgetown, guyana, 44 patients seeking treatment for symptomatic, slide-confirmed malaria were given standard chloroquine (cq) therapy and followed for 28 days. the patients apparently had pure infections with plasmodium falciparum (14), p. vivax (13) or p. malariae (one), or mixed infections either of p. falciparum and p. vivax (17) or of p. falciparum, p. malariae and p. vivax (two). each received supervised treatment with 10 mg cq base/kg on each of days 0 and 1, and ...200212171615
treatment history and treatment dose are important determinants of sulfadoxine-pyrimethamine efficacy in children with uncomplicated malaria in western kenya.this study retrospectively studied amendable determinants of sulfadoxine-pyrimethamine (sp) efficacy involving 2869 treatments among 1072 kenyan children <5 years old who had uncomplicated malaria. the dose was based on age: one-quarter tablet was given to infants <1 year old, one-half tablet was given to 1-3-year-old children, and a full tablet was given to 4-year-old children. only 23.5% received the internationally recommended target dose of 25/1.25 mg of sp per kg of body weight. sp intake i ...200312552431
plasmodium malariae in east timor.a community-based rainy-season malaria prevalence survey was conducted in bobonaro district, in recently independent east timor, in 2001. although the survey was primarily aimed at defining the prevalence of plasmodium falciparum and p. vivax, six individuals with p. malariae infection were identified (prevalence 0.57%). we believe these are the first reported cases of p. malariae from the island of timor.200212757210
proteolytic enzymes of the erythrocytic forms of roden and simian species of malarial plasmodia. 196113881058
studies on malaria and anopheles balabacensis in cambodia.during the past few years anopheles balabacensis has come to be recognized as a very important human malaria vector in thailand and the indochinese area, but little has been published on its bionomics except from north borneo.studies of the feeding habits of a. balabacensis in cambodia showed it to be predominantly a forest mosquito. it was readily attracted to monkeys in the forest canopy but also readily attacked man on the ground. very few of this species were attracted to domestic animals. m ...196414122444
late symptomatic plasmodium malariae relapse in the territory of the former yugoslavia. 200314531987
diagnosis of malaria aided by polymerase chain reaction in two cases with low-level parasitaemia.light microscopy of thick and thin blood smears is the mainstay of malaria diagnosis. in situations of low-level parasitaemia such as drug-modified disease, however, this may be difficult making clinical management problematic. polymerase chain reaction (pcr) methods have shown high sensitivity for the diagnosis of malaria and are able to differentiate the plasmodium species involved. two cases are presented in the present study, which illustrate how a pcr method can aid light microscopic malari ...200314656238
detection of two cases of plasmodium malariae in jharkhand. 200214686111
interference by malaria in the diagnosis of typhoid using widal test alone.a total of 270 febrile patients (130 males and 140 females) aged between 15 and 59 were screened using thick and thin blood film stains for malaria, bacteriologic culture and widal test for enteric fevers. sixty (22%) were positive for malaria while 38 (14%) were positive for enteric fevers out of which 16 (26.6%) concomitantly had malaria parasite. cases without malaria parasite (mp) or enteric fever organism were 172 (63.7%) and classified as pyrexia of unknown origin (puo). forty-four were st ...200314696952
[epidemiology of malaria in a village of sudanese savannah area in mali (bancoumana). 2. entomo-parasitological and clinical study ].we carried out five cross sectional surveys between 1993 and 1994 to assess the epidemiology of malaria in the village of bancoumana, located in the sudanese savannah areas of mali. each survey included a collection of entomological, clinical, parasitological and immunological data. the study population involved 1600 children from six months to 9 years of age. the main vector was anopheles gambiae s.l., man bite rate and entomological inoculation rate were maximum respectively in august (peak of ...200314717049
high prevalence of plamodium malariae infections in a brazilian amazon endemic area (apiacás-mato grosso state) as detected by polymerase chain reaction.plasmodium malariae is commonly confounded with plasmodium vivax at the microscopic examination of thick blood smear. in the present study, we used a nested pcr assay to amplify a species-specific sequence of the 18s ssu rrna gene of plasmodium in blood samples of 497 individuals living in an endemic region of the brazilian amazon basin. we have found that, while the microscopic examination of thick blood smears showed a p. malariae prevalence of 1.2% (6 out of 497), the nested pcr revealed 11.9 ...200414739024
evaluation of the realart malaria lc real-time pcr assay for malaria diagnosis.pcr-based methods have advantages over traditional microscopic methods for the diagnosis of malaria, especially in cases of low parasitemia and mixed infections. however, current pcr-based assays are often labor-intensive and not readily quantifiable and have the potential for contamination due to a requirement for postamplification sample handling. real-time pcr can address these limitations. this study evaluated the performance characteristics of a commercial malaria real-time pcr assay (reala ...200414766829
studies on relapses in blood-induced infections from plasmodium malariae and plasmodium cynomolgi. 195014804091
[relapses due to plasmodium malariae and p. cynomolgi in infections produced by blood inoculations]. 195114864951
response of plasmodium malariae infections to three different drugs; response to metachloridine, chloroguanide (paludrine), and intramuscular chloroquine. 195114873564
studies in the transmission of plasmodium malariae by anopheles mosquitoes. 195114911223
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