| pleural effusion due to infection with histoplasma capsulatum. | | 1970 | 5425307 |
| growth of histoplasma capsulatum. vi. maintenance of the mycelial phase. | a medium is described for the maintenance of the mycelial phases of histoplasma capsulatum in their "original" condition of sporulation. a yeast phase medium is reemphasized, not only for conversion and support of the yeast phase, but as an indirect method of maintaining the mycelial characteristics as originally observed. | 1970 | 5440171 |
| the uptake of low molecular weight sulfur-containing compounds by histoplasma capsulatum and related dimorphic fungi. | | 1970 | 5455792 |
| immunity to histoplasmosis induced in mice by components of histoplasma capsulatum. | | 1970 | 5456424 |
| [1st isolation of histoplasma capsulatum from the soil in minas gerais]. | | 1970 | 5457769 |
| electron microscopic study of phagocytosis of histoplasma capsulatum by hamster peritoneal macrophages. | | 1970 | 5459986 |
| electronmicroscopy of self-parasitism by histoplasma capsulatum and blastomyces dermatitidis. | | 1970 | 5470550 |
| comparison of macrocomplement and microcomplement fixation techniques used in fungus serology. | a comparative evaluation was performed on the micro- and macrocomplement fixation (cf) tests that are used as standard procedures in the serodiagnosis of blastomycosis, coccidioidomycosis, and histoplasmosis. tests with 937 sera from suspected and culturally proven cases of these diseases against yeast-form antigens of blastomyces dermatitidis and histoplasma capsulatum and against the soluble antigens, coccidioidin and histoplasmin, revealed that the microtiters were within +/- 1 dilution of th ... | 1970 | 5498606 |
| evaluation of systemic antifungal agents in x-irradiated mice. | the effect of x irradiation on the survival time of animals experimentally infected with pathogenic fungi was studied, and the activity of antifungal agents in pre-irradiated hosts was evaluated. a 24-hr preinfection dose of x irradiation decreased the survival time of mice infected with cryptococcus neoformans and histoplasma capsulatum to a greater extent than candida albicans or blastomyces dermatitidis infections. exposure to 400 r caused a significant reduction in the variation (s(2)) survi ... | 1970 | 5498613 |
| factors governing the epidemiology of histoplasma capsulatum in soil. | | 1970 | 5535367 |
| histoplasma capsulatum in the environment of sporadic histoplasmosis cases. | | 1970 | 5535371 |
| yeastlike to mycelial phase transformation of histoplasma capsulatum as observed by scanning electron microscopy. | | 1971 | 5548405 |
| biologically oriented organic sulfur chemistry. 7. carbonyl disulfides as inhibitory agents for histoplasma capsulatum. | | 1971 | 5552209 |
| suppressive effect of streptomycin on the phagocytic activity of mouse peritoneal macrophages for histoplasma capsulatum. | | 1971 | 5563955 |
| lanthionine--an organic source of sulfur for growth of yeast-phase cells of histoplasma capsulatum. | | 1971 | 5576436 |
| environmental factors and growth of histoplasma capsulatum in soil. | | 1967 | 5585327 |
| a serological comparison of the three morphological phases of coccidioides immitis; complement fixation tests with anti-histoplasma capsulatum serum. | | 1967 | 5586973 |
| monitored environment system to control cell growth, morphology, and metabolic rate in fungi by oxidation-reduction potentials. | a device for the adjustment, maintenance, and monitoring of a desired oxidation-reduction potential in a liquid environment is described. the filamentous species, penicillium lilacinum and trichophyton schoenleinii, and the dimorphic species, histoplasma capsulatum, developed budding yeastlike cells when grown in a liquid medium with a low oxidation-reduction potential. when the organisms were inoculated into fresh medium, they returned to the filamentous condition as the oxidation-reduction pot ... | 1968 | 5636453 |
| growth response of yeast cells of histoplasma capsulatum to citraed human blood plasma. | | 1968 | 5643054 |
| primary subcultures of histoplasma capsulatum. i. macro and micro-morphology of the mycelial phase. | | 1968 | 5647142 |
| histoplasmosis in italy. i. isolaton of histoplasma capsulatum from dogs in the province of bologna. | | 1968 | 5647148 |
| gymnoascus demonbreunii ajello & cheng evidence that it is not the perfect state of histoplasma capsulatum darling. | | 1968 | 5647150 |
| reduction of a tetrazolium salt in determining growth activity of yeast-phase histoplasma capsulatum. | a colorimetric method using a tetrazolium compound, 3,4,5-dimethylthiozalil-(1 or 2),2,5-diphenyltetrazolium bromide (ttbr), was developed for studying the growth activity of yeast-phase histoplasma capsulatum. materials extracted in phosphate buffer, ph 7.0, from cells at different stages of growth reduced ttbr. colorimetric changes were correlated with enzymatic activity. under standardized conditions specified herein, the optical density of the reduced tetrazole was an index of the growth act ... | 1968 | 5650776 |
| inhibition of histoplasma capsulatum by candida albicans and other yeasts on sabouraud's agar media. | the inhibition of growth of histoplasma capsulatum by candida albicans and other yeasts on sabouraud's agar was investigated. histoplasma (yeast-phase inoculum) was grown alone and in mixtures with yeasts at 25 c for 4-week periods. as few as 10 colonies of c. albicans completely inhibited the growth of approximately 50,000 potential colonies of histoplasma. the ph was determined in cultures of 36 colonies of candida on media containing 1, 2, and 4% glucose by spotting the agar with ph indicator ... | 1968 | 5669894 |
| histoplasma capsulatum in a human eye. | | 1968 | 5673036 |
| the natural occurrence of histoplasma capsulatum in a cave. 3. effect of flooding. | | 1968 | 5673490 |
| variation in enzymatic activities among strains of histoplasma capsulatum and histoplasma duboish. | | 1968 | 5679665 |
| fungi found in association with histoplasma capsulatum in a naturally contaminated site in clarksburg, maryland, u.s.a. | | 1968 | 5679671 |
| differences in the distribution of sensitivity to histoplasmin and isolations of histoplasma capsulatum. | | 1968 | 5691738 |
| isolation of histoplasma capsulatum from a texas cave. | | 1968 | 5696717 |
| estimation of the number of viable particles of histoplasma capsulatum in soil. | | 1968 | 5696720 |
| effects of various compounds on growth of yeast cells of histoplasma capsulatum. | | 1968 | 5696725 |
| the possibel role of uric acid in the ecology of histoplasma capsulatum. | | 1968 | 5696730 |
| sporulation characteristics of histoplasma capsulatum. | | 1968 | 5700471 |
| varying virulence in rabbits infected with different filamentous types of histoplasma capsulatum. | histoplasma capsulatum filamentous primary isolates and their subcultures are separable into two distinct colonial types (a and b) having different microscopic characteristics. yeast forms of the a and b types and the parent (p) strains from which they are derived are microscopically indistinguishable. critically standardized inocula of living p, a, and b yeasts from one strain of h. capsulatum (g-184) were injected intravenously into 12 rabbits. each type produced progressively debilitating dis ... | 1968 | 5726296 |
| variation of rates of natural infection with histoplasma capsulatum in bats. | | 1969 | 5764198 |
| antibodies to histoplasma capsulatum in human and animal populations of southeastern minnesota. | | 1969 | 5765636 |
| pulmonary disease caused by mycobacterium xenopei and histoplasma capsulatum. a case report. | | 1969 | 5767591 |
| variability in virulence of strains of histoplasma capsulatum. | | 1969 | 5767594 |
| effect of thimerosal on the whole yeast phase antigen of histoplasma capsulatum. | | 1969 | 5768605 |
| protoplasts of systemic dimorphic fungal pathogens: histoplasma capsulatum and blastomyces dermatitidis. | | 1969 | 5768613 |
| isolation of histoplasma capsulatum from bats in oklahoma. | | 1969 | 5768774 |
| effect of histoplasmosis on antibody response to an erythrocyte antigen. | infection of mice with histoplasma capsulatum depressed their ability to form agglutinins against foreign erythrocytes. animals previously inoculated with 10(8) yeast cells of h. capsulatum showed the most significant depression, occurring when erythrocytes were injected 8 days after infection. the average log(2) hemagglutinin titer was 2.7 compared to 8.0 for the control (noninfected) group. in general, depression of hemagglutinin response in all infected mice was greatest 8 days after infectio ... | 1969 | 5773012 |
| systemic antifungal activity of pyrrolnitrin. | the antifungal activity of pyrrolnitrin, previously shown to be effective against superficial infections, was evaluated against experimental systemic mycoses. pyrrolnitrin was inhibitory in vitro at <0.78 to 100 mug/ml to candida albicans, cryptococcus neoformans, blastomyces dermatitidis, sporotrichum schenckii, and histoplasma capsulatum. pyrrolnitrin activity was reduced about 90% in sera. after multiple subcutaneous doses of pyrrolnitrin at 20 mg/kg, activity was recovered in mouse blood and ... | 1969 | 5785951 |
| [fungistatic and fungicidal effect of phenol, lysol and formaldehyde on the fungi coccidioides immitis 7-86, histoplasma capsulatum 6652, and blastomyces dermatitidis 6064]. | | 1969 | 5787564 |
| rupture of abdominal aorta by histoplasma capsulatum. | | 1969 | 5787799 |
| an experimental model for studying extrapulmonary dissemination of histoplasma capsulatum in hamsters. | | 1969 | 5796693 |
| inhibitory effects of organic sulfur compounds on histoplasma capsulatum. | | 1969 | 5797624 |
| histoplasmic (histoplasma capsulatum) infection in a horse. | | 1969 | 5813749 |
| a survey to determine the occurrence of histoplasma capsulatum and cryptococcus neoformans in air-conditioners. | | 1969 | 5816169 |
| a study of fungi found in association with histoplasma capsulatum: three bird roosts in s. e. missouri, u.s.a. | | 1969 | 5817912 |
| cross-protection between histoplasma capsulatum and oidiodendron kalrai in mice. | | 1969 | 5818812 |
| coincidence of mycotic (histoplasma capsulatum) vegetative endocarditis of the mitral valve and the lutembacher syndrome. report of a case. | | 1965 | 5825550 |
| isolation of histoplasma capsulatum from bats of el salvador. | | 1965 | 5829137 |
| pseudocavitary histoplasmosis: infection of emphysematous bullae by histoplasma capsulatum. report of a case. | | 1965 | 5830930 |
| [1st case of histoplasmosis observed on the french somali coast. ulceration of the soft palate due to histoplasma capsulatum]. | | 1965 | 5835063 |
| soluble antigenic constituents of yeast-phase histoplasma capsulatum. | | 1965 | 5843838 |
| occurrence of dermatophytes in fresh bat guano. | evidence is presented in support of the hypothesis that fresh bat guano serves as a means of pathogenic fungi dissemination in caves. a total of 371 guano samples were collected from caves in southeastern new mexico. each sample was agitated in sterile saline and sand. the supernatant fluid was treated with an antibiotic and streaked on differential media. cultures were incubated at 25 and 37 c and examined at intervals over a 4-week period. for animal inoculation, highly concentrated inoculum w ... | 1965 | 5867652 |
| isolation of histoplasma capsulatum from feathers of chickens inoculated intravenously and subcutaneously with the yeast phase of the organism. | | 1965 | 5873441 |
| feathers as substrate for histoplasma capsulatum in its filamentous phase of growth. | | 1965 | 5873442 |
| a comparative morphological study of the yeast phases of histoplasma capsulatum and histoplasma duboisii. | | 1964 | 5874139 |
| cross reactions to histoplasma capsulatum in mice. | | 1964 | 5874808 |
| respiratory infection of mice with histoplasma capsulatum. | | 1965 | 5876685 |
| improved technique for the reversion of histoplasma capsulatum in tissue culture. | | 1965 | 5876909 |
| nutritional studies of histoplasma capsulatum. | | 1965 | 5877181 |
| [isolation of histoplasma capsulatum from soil in uruguay]. | | 1965 | 5899462 |
| immunoelectrophoretic studies of sera from rabbits exprimentally infected with histoplasma capsulatum. | adamson, david m. (university of oklahoma, norman), and george c. cozad. immunoelectrophoretic studies of sera from rabbits experimentally infected with histoplasma capsulatum. j. bacteriol. 92:887-891. 1966.-in a study involving 24 mature dutch rabbits inoculated intravenously with 2.6 x 10(8)histoplasma capsulatum yeast cells per kg of body weight, all rabbits were shown to develop precipitins by the end of the 5th week. precipitins were demonstrated both by the micro-ouchterlony method and mi ... | 1966 | 5926755 |
| chemical decontamination of soil containing histoplasma capsulatum. | | 1966 | 5930777 |
| survey of soils for human pathogenic fungi from the emilia-romagna region of italy. ii. isolatìon of allescheria boydii, cryptococcus neoformans and histoplasma capsulatum. | | 1966 | 5930779 |
| further ecological studies of the growth of histoplasma capsulatum in nature. | | 1966 | 5938578 |
| experimental infection of north american insectivorous bats (tadarida brasiliensis) with histoplasma capsulatum. | | 1966 | 5941177 |
| antigenic properties of the cell wall and other fractions of the yeast form of histoplasma capsulatum. | pine, leo (communicable disease center, atlanta, ga.), clarence j. boone, and dave mclaughlin. antigenic properties of the cell wall and other fractions of the yeast form of histoplasma capsulatum. j. bacteriol. 91:2158-2168. 1966.-yeast-form cells of histoplasma capsulatum were fractionated in an attempt to obtain complement-fixing antigens with greater specificity than those of the currently used whole yeast form. no specific fraction was isolated. rupture of the whole cell produced soluble an ... | 1966 | 5943933 |
| isolation of histoplasma capsulatum from bats in the united states. | | 1966 | 5944726 |
| diagnostic possibilities of utilizing precipitation in agar for the identification of histoplasma capsulatum, coccidioides immitis, blastomyces dermatitidis and paracoccidioides brasiliensis. | | 1966 | 5950913 |
| parasitism of monolayer cultures of dog tissue by histoplasma capsulatum. i. preliminary investigations. | | 1966 | 5973430 |
| first romanian isolation of histoplasma capsulatum from the soil. | | 1966 | 5988597 |
| sexual reproduction in histoplasma capsulatum. | | 1967 | 6020299 |
| antibodies in histoplasmosis. | production of precipitating and complement-fixing antibody in rabbits and other animals was induced by immunization with live yeast-phase cells of histoplasma capsulatum. results of studies of polysaccharide antigens from three strains of h. capsulatum, by quantitative complement-fixation with human and rabbit antisera, strongly suggest the presence of type specificity. the variations of titer during 11 weeks in one patient with histoplasmosis and the variations of titer among a group of patient ... | 1967 | 6020413 |
| effect of temperature on the intracellular growth of histoplasma capsulatum. | the rate and form of growth of histoplasma capsulatum within histiocytes derived from homothermic and poikilothermic animals, and incubated at 25, 30, and 37 c, are described. the generation time of the fungus in mouse cells incubated at 37 and 25 c was 11 and 24 hr, respectively. blastospore formation was progressively retarded in cells at 25 c, and this retardation was accompanied by germination of some of the blastospores. the generation time of the fungus in mouse cells incubated at 30 c was ... | 1967 | 6020414 |
| histoplasma capsulatum in a human eye. | | 1967 | 6022243 |
| granulomatous oral ulceration due to histoplasma capsulatum. | | 1967 | 6024390 |
| cell wall studies of histoplasma capsulatum. | | 1967 | 6036225 |
| comparative study of the cell walls of the yeastlike and mycelial phases of histoplasma capsulatum. | cell walls were prepared from the yeastlike and mycelial phases (yp and mp) of histoplasma capsulatum and from saccharomyces cerevisiae by mechanical disruption and washing. lipids were extracted with methanol-ether, chloroform, and acidified methanol:ether; a final extraction was made with ethylenediamine. the lipid contents of h. capsulatum yp and mp walls were about the same. qualitative and quantitative analyses were made of the products obtained from treatment of the cell walls, or fraction ... | 1967 | 6039363 |
| sexual reproduction in histoplasma capsulatum. | | 1967 | 6042868 |
| deposition of histoplasma capsulatum in the subcutaneous tissues and feathers of inoculated chick embryos. | | 1967 | 6048617 |
| the use of formalin to kill histoplasma capsulatum at an epidemic site. | | 1967 | 6067016 |
| laboratory examination of organic fungicides against zoopathogenic fungi in soil. | seven commercial and five experimental organic fungicides were tested against histoplasma capsulatum, cryptococcus neoformans, allescheria boydii, and sporotrichum schenckii in a series of laboratory studies. preliminary agar dilution plate tests indicated that lanstan, dac 649, dac 469, dac 2787, he 3944, maneb, and nabam, in order of decreasing activity, inhibited all test fungi. terraclor, dexon, and he 13274 were active only in high concentration. the best fungicidal properties were exhibite ... | 1967 | 6077420 |
| in vitro studies with r 51,211 (itraconazole). | the in vitro activity of r 51,211 (itraconazole, accepted generic name; janssen pharmaceutica, beerse, belgium), a new orally active triazole, was compared with those of two existing orally active azoles, ketoconazole and bay n 7133, and a topical agent, ro 14-4767/002. an agar dilution procedure (kimmig agar) was performed with 148 isolates of pathogenic fungi. incubation was at 30 degrees c from 48 h to 7 days. r 51,211 was dissolved in 0.2 n hcl in absolute ethanol, ketoconazole was dissolved ... | 1984 | 6089654 |
| hematogenous histoplasmosis in the immunocompromised child. | hematogenous (disseminated) histoplasmosis occurred in 31 of 4158 children with cancer or immune deficiency disorders. approximately half of the 31 patients had pulmonary lesions, reacted to the histoplasmin skin test, and generated complement-fixing antibodies to histoplasma capsulatum. in a comparative study delayed hypersensitivity to histoplasmin was demonstrated in 36 (5.7%) of 634 children at the time of diagnosis of cancer. patients with cancer who were reactive to histoplasmin before tre ... | 1984 | 6090628 |
| disseminated histoplasmosis in patients with the acquired immune deficiency syndrome. | the ongoing epidemic of acquired immune deficiency syndrome (aids) has affected homosexual men, intravenous (iv) drug abusers, haitians, hemophiliacs, and others. defects in cell-mediated immunity place these patients at risk for opportunistic infections. we recently saw three men from alabama with disseminated infection due to histoplasma capsulatum. two of these men were homosexual and the other was an iv drug abuser. these three patients had evidence of depressed cellular immunity consistent ... | 1984 | 6093723 |
| immunoregulation in experimental disseminated histoplasmosis: flow microfluorometry (fmf) studies of the thy and lyt phenotypes of t lymphocytes from infected mice. | previous studies have shown that mice infected i.v. with 6 x 10(5) yeast phase histoplasma capsulatum (hc) develop suppressed immune responses during weeks 1 to 4 of infection but that by weeks 8 to 12 of infection these responses return to normal. in this study total and differential cell counts showed that as early as the third day of infection there was a marked reduction in the number of lymphocytes recovered from the peripheral blood, bone marrow, and thymus of infected animals. concomitant ... | 1983 | 6134775 |
| comparative study of a new chrysosporium species with histoplasma capsulatum. | the chrysosporium state of a new ascomycete, renispora flavissima (gymnoascaceae), resembles histoplasma capsulatum in its macroconidial morphology. it was discovered growing in bat guano, from which it was readily isolated by direct plating of diluted soil, but only rarely from mice inoculated with soil suspensions. the fungus was consistently reisolated from tissues of mice inoculated intravenously and intraperitoneally with conidial and mycelial suspensions from cultures of the fungus. nevert ... | 1980 | 6158762 |
| new, special stain for histopathological diagnosis of cryptococcosis. | the masson-fontana silver stain for melanin was employed for the differentiation of pathogenic fungal species in human or mouse tissues. the fungi studied were candida albicans, candida tropicalis, candida glabrata (torulopsis glabrata), cryptococcus neoformans, cryptococcus bacillisporus, coccidioides immitis, blastomyces dermatitidis, histoplasma capsulatum, paracoccidioides brasiliensis, sporothrix schenckii, rhizopus rhizopodiformis, and aspergillus fumigatus. the tissue sections stained wit ... | 1981 | 6162857 |
| serological cross-reactivity between sporothrix schenckii and various unrelated fungi. | the serological cross-reactivity of sporothrix schenckii with various unrelated fungi was investigated by use of immunodiffusion tests. a rabbit anti s. schenckii serum was obtained, which reacted with cladosporium werneckii, c. carrionii, c. bantianum, coccidioides immitis, phialophora jeanselmei, p. gougerotii, p. dermatitidis, fonsecaea pedrosoi, aspergillus fumigatus, histoplasma capsulatum and trichophyton mentagrophytes, but not with saccharomyces cerevisiae antigens. the serological deter ... | 1981 | 6163987 |
| comparison of selective staining of fungi in paraffin sections by light microscopy, sem and bei. | paraffin-embedded sections from human tissues with fungi or organisms classified with fungi were studied by light microscopy (lm), scanning electron microscopy (sem), and the backscatter electron imaging (bei) mode of the sem. the fungal organisms selected for study were those familiar to the pathologist on the basis of their appearance in paraffin-embedded material stained with the gomori-grocott chromic acid methenamine silver stain (gms). the organisms were actinomyces, rhizopus, cryptococcus ... | 1981 | 6172842 |
| an enzyme immunoassay for yeast and mycelial phase-specific antibodies in histoplasmosis. | the enzyme-linked immunosorbent assay (elisa) has been adapted to detect class-specific antibodies to yeast and mycelial phase (mp) antigens of histoplasma capsulatum. experimental histoplasmosis was produced in rhesus monkeys and humoral immune responses were measured by elisa and complement-fixation (cf) tests. antibodies to the yeast phase (yp) reached a peak after 7 weeks and gradually declined thereafter, while mp antibodies continued to increase even after 4 months. comparison of the 2 tes ... | 1982 | 6177791 |
| antigens from histoplasma capsulatum and blastomyces dermatitidis. i. immunological comparative studies from polysaccharide-protein complexes of both fungi. | certain groups of fungi share chemical structures which makes difficult isolation and differentiation of specific antigens by the usual methods of extraction and purification. therefore, we have oriented our studies to the immunological and biochemical characterization of differences and similarities of molecular structures from fungi, etiologic agents of systemic mycoses, hoping to establish criteria for the utilization and handling of these antigens. a deproteinized polysaccharide-protein comp ... | 1982 | 6178974 |
| acid-fastness of fungi in blastomycosis and histoplasmosis. | in 60% of the infections caused by blastomyces dermatitidis and in 47% of the infections caused by histoplasma capsulatum, some of the organisms are acid-fast in tissue sections. treatment with 1n hydrochloric acid at 60 degrees c abolishes the acid-fastness of h capsulatum, which indicates that the acid-fastness may be related to mycolic acid. organisms of b dermatitidis, however, remain acid-fast in 83% of the sections treated with acid. the presence of acid-fastness in small cells can aid in ... | 1982 | 6180697 |
| immunoregulation in disseminated histoplasmosis: characterization of the surface phenotype of splenic suppressor t lymphocytes. | c57bl/6 and c3h/hej mice were infected intravenously with 6 x 10(5) yeast-phase histoplasma capsulatum organisms. after 1 week, splenocytes from both mouse strains showed diminished antibody responses to sheep erythrocytes in vitro; these cells also were able to suppress the response of normal syngeneic cells. passage of splenocytes from infected mice through a nylon wool column yielded a population enriched for t cells that exerted suppressor activity, although to a smaller extent than did unfr ... | 1982 | 6182106 |
| fungal autofluorescence with ultraviolet illumination. | fungal autofluorescence of hematoxylin and eosin (h & e)-stained tissue sections viewed under ultraviolet illumination was evaluated for diagnostic utilization. cases examined included coccidioidomycosis, candidiasis, aspergillosis, mucormycosis, and histoplasmosis. the method was most useful in identifying coccidioides immites, candida spp., and aspergillus spp. in sections from solid parenchymatous organs, loose connective tissue, granulomata, or necrotic tissue debris. the architectural detai ... | 1983 | 6186138 |