| preliminary x-ray crystallographic data on phospholipase c from bacillus cereus. | | 1978 | 97390 |
| effects of ethylenediaminetetraacetic acid-4 sodium solution on the surface of renal calculi and the uroepithelium. | tetrasodium ethylenediaminetetraacetic acid is one of the most effective agents that dissolve renal calculi, especially calculi containing calcium. to study the dissolving process of calculi in solutions, with or without trypsin, serial thin sections of renal calculi composed of calcium oxalate and/or phosphate were prepared and observed by polarizing microscopy. the effects of the solution on the surface of human renal calculi and rat uroepithelium also were studied by scanning electron microsc ... | 1978 | 97399 |
| [results of early nutrition of newborn infants with low birth weight. ii. effects of early nutrition on bilirubin metabolism of newborn infants with birth weights from 1501 to 2000 g]. | | 1978 | 97464 |
| [transplantation of the big toe from the foot to the hand in monkeys using a microsurgical technic]. | | 1978 | 97465 |
| effects of pelleting and sterilization of diet on 2 strains of rabbit coccidia. | both autoclaving and irradiation at levels currently used for other laboratory animal diets appear to be satisfactory for the elimination of 2 of the most robust and pathogenic species of rabbit coccidia. pelleting by the usual methods, even at 68 degrees c, was found to be unsatisfactory in eliminating all oocysts from heavily infected diet. | 1978 | 97471 |
| evidence that serotonin neurons stimulate secretion of prolaction releasing factor. | | 1978 | 97485 |
| effects of intrahepatic transplantation of pancreatic islets on hepatic metabolism in the rat. | | 1978 | 97491 |
| the preparation and use of antibodies as diagnostic biochemical probes. | | 1978 | 97493 |
| divalent cation mobility throughout exponential growth and sporulation of bacillus megaterium. | each of the five elements considered was taken up by bacillus megaterium during exponential growth. initial mg and mn uptake was rapid and ended by mid-log. for ca, fe, and zn, uptake continued throughout exponential growth. elements were released from the cells immediately following initial uptake. for mn, egression continued to t2, with release of 36% of total accumulated. secondary uptake followed immediately and continued through stage v. magnesium egression continued to t1 with release of 3 ... | 1978 | 97497 |
| pressure dissociation of bacterial ribosomes and reassociation of ribosomal subunits. | | 1978 | 97513 |
| new regulatory mutations affecting the expression of the threonine operon in escherichia coli k-12. | the promoter of the threonine operon was joined to the structural genes of the lac operon in escherichia coli k 12. the synthesis of beta-galactosidase was thus repressed by threonine plus isoleucine in the fusion strains. to isolate mutations which affect the expression of the threonine operon, alterations in the level of expression of the lacz gene were selected. a new type of regulatory mutation was discovered. | 1978 | 97515 |
| effects of learned safety and tolerance on alcohol consumption by the rat. | evidence is presented that learned safety increases the rat's willingness to drink ethanol: induction of tolerance to ethanol following learned safety training produces a further increase. rats with chronically implanted intragastric fistulae consumed substantially more (30%) alcohol when aversive post-ingestional effects were minimized by draining stomach contents during drinking than did rats allowed to retain stomach contents. half the rats from each group were then made tolerant by prolonged ... | 1978 | 97706 |
| the reinforcing property of ethanol in the rhesus monkey ii. some variables related to the maintenance of intravenous ethanol-reinforced responding. | | 1978 | 97716 |
| tropical diseases. | | 1977 | 97727 |
| relations between fatty acids and oestrogen binding properties of pure rat alpha 1-foetoprotein. | a delipidation procedure based on treatment with charcoal at ph 3 has been applied to highly purified rat alpha 1-foetoprotein preparations. the oestrogen binding properties of the delipidated proteins have been studied with an equilibrium dialysis technique, and compared with the properties of the untreated foetal protein, as well as those of preparations reconstituted from the defatted alpha 1-foetoprotein and the removed lipids. an important increase has been evidenced for the binding levels ... | 1979 | 90528 |
| [effect of ergoline derivatives on platelet and blood vessels]. | the influence of dihydrogenated ergot alkaloids on vessels and blood platelets was studied in vitro and in vivo. at low concentrations they cause contraction of isolated vein strips via a stimulation of alpha-adrenoceptors, at higher concentrations they antagonize the action of noradrenaline on arteries and veins and inhibit the adrenaline-induced platelet aggregation in vitro. in volunteers, intravenous and subcutaneous administration of dihydroergotamine (dihytamin) caused a decrease in blood ... | 1979 | 94864 |
| visualization of mitochondrial coupling factor f1(atpase) by freeze-drying. | it is known that the negatively stained preparations of inner mitochondrial membrane display characteristic approximately 9 nm f1 (atpase) knobs projecting from the matrix surface. freeze-etch studies have reported the absence of such knobs from the "etched" surface of the inner mitochondrial membranes. we have demonstrated their presence on the surface of smp (submitochondrial particles) prepared by freeze-drying for transmission electron microscopy. this identification has been substantiated b ... | 1979 | 95168 |
| effects of ovarian hormones on cell membranes in the rat uterus. i. freeze fracture studies of the apical membrane of the liminal epithelium. | freeze fracture techniques have been used to study the apical membrane of cells of the luminal epithelium of the rat uterus under various hormonal regimes. in the ovariectomized but otherwise untreated rat, intramembranous particles (imps) occur at a density of 1395 +/- 122 per micron 2; they appeared spherical and uniformly distributed. after 3 days treatment with estrogen, no change in appearance or density was found, but 3 days of progesterone treatment produced a significant increase in imp ... | 1979 | 95176 |
| spontaneous termination of reentry ventricular tachycardia in the late myocardial infarction period: an experimental study in the dog. | forty episodes of induced ventricular tachycardia in the late myocardial infarction period (4-6 days old) were analyzed in 12 dogs in an attempt to identify the possible mechanisms for the termination of reentry tachycardia. multiple epicardial and endocardial composite electrograms were recorded in and around the central ischemic zone of the infarction. during tachycardia, the earliest site of activation was identified in the epicardial surface of the border or normal zone immediately adjacent ... | 1979 | 95291 |
| formation of hcg in the human fetoplacental unit. | hcg and beta-hcg were determined in umbilical arterial and venous blood immediately after spontaneous term delivery. hcg and beta-hcg are present in higher concentrations in arterial than in venous umbilical cord blood. the data are consistent with the hypothesis that hcg and beta-hcg are produced in the fetal compartment of the human fetoplacental unit, with a larger contribution of the female fetus as compared with the male. | 1979 | 95667 |
| determination of the human lymphokine leukocyte migration inhibitory factor (lif) by a sensitive radioenzymatic assay. inhibitory effect of cgmp on the esterolytic activity of highly purified lif. | indirect experiments using irreversible enzyme inhibitors have shown that the human lymphokine leukocyte migration inhibitory factor (lif) is a serine esterase and protease exhibiting specific affinity towards arginine esters and amides. a sensitive assay for direct measurement of esterase activity using p-tosyl-l-arginine (3h) methyl ester (3h-tame) as substrate is described. esterolytic activities are demonstrated in crude supernatants of human lymphocytes stimulated with concanavalin a (lif-r ... | 1979 | 95804 |
| effects of intestinal amylase and trypsin on pancreatic secretion in the pig. | pigs were surgically prepared with external pancreatic fistulae and duodenal cannulae in order to elucidate whether the proposed intestinal feedback control of pancreatic secretion in the pig--as in rat and man--is exerted by trypsin. furthermore, the effect of intraluminal amylase on pancreatic secretion was studied. reintroduction of pancreatic juice into the duodenum or infusion of trypsin into the duodenum depressed the volume of the pancreatic flow and the protein output markedly. introduct ... | 1979 | 93774 |
| dna-directed cell-free protein-synthesizing system of bacillus subtilis. | a cell-free coupled system of transcription and translation using cell extracts from bacillus subtilis and dna from phage sp82 has been developed. under optimum conditions, it incorporated approx. 300 pmol methionine during a 1 h incubation. the activity of the system increased linearly as the concentration of s-150 supernatant fraction protein increased from 125 to 325 microgram per assay. the optimum mg2+ concentration was 12.5-15 mm. ribosomes required treatment with dnaase in order to reduce ... | 1979 | 93969 |
| distribution and nature of desmosomes in the bovine developing ruminal epithelium. | desmosomes entirely similar to those of the deeper layers of ruminal epithelium are seen in the luminal layers of the early fetal ruminal epithelium. in the older fetuses, these desmosomes have morphological features that reveal to some extent the occurrence of processes of keratinization. this could indicate that the basis for cell keratinization is already present in the fetus and that postnatal keratinization corresponds mainly to the full development of the prenatally existing pattern of dif ... | 1979 | 94228 |
| laboratory investigations of an epidemic of acute haemorrhagic conjunctivitis in bombay and poona in 1975. | | 1978 | 96187 |
| hepatitis b viral dna molecules have cohesive ends. | hepatitis b virus dna made fully double stranded by a virion dna polymerase reaction could be converted from circular to linear molecules by heating in 10 mm nacl at 77 degrees c or in 100 mm nacl at 90 degrees c for 15 min. heat-generated linear hepatitis b virus dna was reannealed to circular molecules by incubating in higher salt concentrations. the identity of the molecular forms was established by their electrophoretic mobility and appearance in electron micrographs. recircularization was b ... | 1979 | 94358 |
| direct demonstration of immunoglobulin kappa chain rna in thymus t cells by in situ hybridization. | mouse thymuses with more than 99% t cells have been reported to contain immunoglobulin kappa mrna-like molecules (kappa rna) in relatively large quantities. the present study was undertaken to rule out the possibility that the kappa rna was mainly a product of a few contaminating b cells of the thymus and to determine whether all t-cell subpopulations contained kappa rna. by in situ hybridization with dna complementary to kappa mrna (kappa cdna) the following observations were made: 98.5% of thy ... | 1978 | 96443 |
| effects of phenytoin on refractoriness and conduction in the human heart. | using his bundle electrograms and the atrial (a2) and ventricular extrastimulus (v2) techniques, anterograde and retrograde refractory period studies were performed (in 9 and 12 patients, respectively) before and 10 min after intravenous infusion of phenytoin (dph; mean plasma level, 17.3 micrograms/ml). dph had no effect on the duration of the qrs complex or the h-v interval of the sinus beats; it had variable but insignificant effects on the sinus rates and the atrial, a-v nodal, and ventricul ... | 1979 | 94379 |
| [study of the spiral and spindle-shaped formations in cultures of bacillus larvae (white 1906) causing foulbrood in bees]. | the authors have been studying the bacterial diseases of the brood for a fairly long time. american and european foul brood has been studied with the highest attention. cultures of bacillus larvae (white, 1906) were examined both in freshly isolated strains and in collection strains of this micro-organism. in cases of foul brood, the pathological material was found to contain not only the typical rods of b. larvae but also immobile spiral forms which are usually referred to in literature as frag ... | 1978 | 96576 |
| a sarcocystis-like protozoon in a sheep with lymphadenopathy and myocarditis. | a generalized enlargement of the lymph nodes was found in an emaciated adult ewe. additional autopsy findings included tiny grey-white necrotic foci in the heart muscle, aspiration pneumonia and diffuse pleuritis. light microscopy showed a generalized lymphadenopathy with perilymphadenitis, depletion of lymphocytes and histiocytosis of the lymph node. in histiocytes and vascular endothelial cells of lymph nodes, septal capillary endothelium of lungs and capillary endothelium of myocardium, early ... | 1978 | 96578 |
| unpredictable response of pseudomonas aeruginosa to synergistic antibiotic combinations in vitro. | the combined activity of ticarcillin and each of three aminoglycosides, gentamicin, tobramycin, and amikacin, was studied with 45 clinical isolates of pseudomonas aeruginosa. all strains individually were susceptible to each of these agents. comparison of the results revealed highly variable interaction, both from strain to strain and from one aminoglycoside to another against the same strain. against 11 strains, none of three antibiotic pairs tested was synergistic by conventional criteria; aga ... | 1978 | 96736 |
| antibody against rabbit immunoglobulin vh and l chain allotype determinants in heterologous anti-ig antisera. | heterologous anti-rabbit igg antisera have been examined by radioimmunoassay for the occurrence of anti-vh antibody. most of the sera contained antibody specific for vh allotype determinants (aal). the antisera contained as much or more anti-al antibody as estimated in conventional alloantisera. it has further been shown that the anti-l chain antibody in all these sera was specific for l chain allotype determinants. antibody against h chain-dependent l chain conformational determinants or cross- ... | 1978 | 97086 |
| antiarrhythmic and hemodynamic actions of flecainide acetate (r-818) in the ischemic porcine heart. | the antiarrhythmic activity of flecainide acetate (r-818), 2 mg/kg, was investigated in anesthetized, open-chest pigs. ventricular arrhythmias were provoked by reducing the flow in the left anterior descending coronary artery (lad) to 25% of control during 30 min. during this period ventricular fibrillation occurred in 33% (11 out of 33) of control animals against 12.5% (1 out of 8) of animals treated with flecainide. ventricular tachycardias were seen in 42% (14 out of 33) of the untreated anim ... | 1979 | 94625 |
| studies on the role of vasopressin in blood pressure control of spontaneously hypertensive rats with established hypertension (shr, stroke-prone strain). | we investigated the role of arginine-vasopressin (avp) in maintaining the blood pressure of spontaneously hypertensive (sh) rats (stroke-prone strain) with established hypertension (22--28 weeks of age). in comparison with normotensive wistar kyoto (wky) rats, plasma avp concentrations of sh rats with benign hypertension (bh) were elevated twofold and in rats with severe or malignant hypertension (s-mh), fourfold. the height of the blood pressure was quantitatively related to plasma avp in both ... | 1979 | 94626 |
| thyroxine and propylthiouracil effects on alpha- and beta-adrenergic receptor number, atpase activities, and sialic acid content of rat cardiac membrane vesicles. | | 1979 | 94627 |
| concentration dependence of the binding of ouabain to isolated guinea pig atria. | | 1979 | 94634 |
| regulation of expression of type c virion dna polymerase (reverse transcriptase) in human x mouse and human x rat hybrid cells. | human cells from 13 different individuals were fused to mouse and rat cells producing abundant type c viral particles. the results demonstrate that incorporation of active dna polymerase (reverse transcriptase) into mature type c particles is suppressed in many of the hybrid clones but not in the parental mouse cell clones. this low particle-associated dna polymerase phenotype was a heritable trait for over 100 cell generations but reversion to a high particle-associated dna polymerase phenotype ... | 1979 | 94700 |
| determination of metabolite compartition in hepatic cells by varying the redox state in vivo. | in the present study, metabolite (lactate, pyruvate, glycerol 3-phosphate, dihydroxyacetone phosphate) concentrations were measured in various redox states. the mathematical relations between metabolite concentrations in various redox states were expressed algebraically and studied. models which provided separate lactate/pyruvate (l/p) and glycerol 3-phosphate/dihydroxyacetone phosphate (g/d) spaces correspond to the experimental results in the case of "reductants" (e.g. ethanol, acetaldehyde, d ... | 1979 | 94822 |
| [hl-a and disease: physiopathological role of the major histocompatibility complex]. | | 1978 | 97767 |
| evaluation of spiramycin as a therapeutic agent for elimination of nasopharyngeal pathogens. possible use of spiramycin for middle ear infections and for gonococcal and meningococcal nasopharyngeal carriage. | varying doses of spiramycin were administered orally to healthy volunteers, and concentrations in serum and saliva were determined. the absorption of the drug was not significantly influenced by concomitant food intake. saliva peak concentrations were 1.3--4.8 times higher than peak concentrations in serum. the elimination half life was 2--3 h in serum, and 4--8 h in saliva. accumulation of the drug was seen in saliva but not in serum. the possible effect of spiramycin in eliminating bacteria fr ... | 1978 | 97775 |
| isolation care of infection-prone burn patients. | an experimental and clinical study of spread of colonisation between burn patients, and their susceptibility to infection, was performed. burn patients' polymorphonuclear neutrophil granulocytes (pmn) functioned poorly, particularly during the second week after injury which coincided with maximum growth of bacteria in the burn wound. patients with large burns often dispersed s. aureus and ps. aeruginosa but also beta-hemolytic streptococcus to the air of their rooms. airborne transfer of these b ... | 1978 | 97776 |
| rickettsiae: a new vaccine for rocky mountain spotted fever. | | 1978 | 97783 |
| post partum patterns of circulating fsh, lh, prolactin, estradiol, and progesterone in nonsuckling cynomolgus monkeys. | circulating levels of fsh, lh, prolactin (prl), estradiol (e), and progesterone (p) were determined by ria in four intact and four monkeys luteectomized (clx) at parturition in order to a) characterize the patterns of these hormones during the puerperium, and b) examine a possible inhibitory role of the "rejuvenated" corpus luteum (cl) on the resumption of follicle growth post partum. in both groups during the first four weeks, fsh and lh were at tonic levels typical of ovulatory cycles. recurre ... | 1978 | 97808 |
| [sarcocyst resistance to certain factors]. | | 1978 | 97852 |
| [personal prophylaxis of venereal diseases]. | | 1978 | 97875 |
| [an index of blood neutrophil injury in man and animals immunized with live anthrax vaccine]. | the authors present the results of study of the blood neutrophil injury in guinea pigs, rabbits, monkeys, and also humans inoculated subcutaneously with live anthrax vaccine. along with intradermal test with anthraxin, the mentioned test is suggested to assess the immunological status of persons immunized with anthrax vaccine. | 1978 | 97884 |
| [prospects for the use of blood substitutes made in the ussr with the expired date of validity]. | as revealed, blood substitutes--aminopeptide, caseine hydrolysate, and hydrolysine with the expired date of validity could be used as the basis of nutrient media for the cultivation of bacteria. bacterial growth proved to be the optimum in addition to the blood substitutes of a 0.25--0.5% of yeast extract. | 1978 | 97885 |
| changes in the activity of certain lysosomal enzymes in the blood serum and organs of rats subjected to fractionated whole body irradiation with 60 co. | | 1977 | 97933 |
| epidemiology and treatment of dog bites in ibadan: a 12-year retrospective study of cases seen at the university college hospital ibadan (1962-1973). | a retrospective epidemiological study was made of dog bite accidents seen at the casualty department of the university college hospital, ibadan, between 1 january 1962 and 31 december 1973. a variety of host, agent and environmental factors were analysed. the incidence per 1000 attendances was 11.5 with a male/female ratio of 57:43. majority of the bites occurred in the dry season and 75.4% of the victims were less than 20 years of age. 83.5% of the bites were inflicted on the extremities and 59 ... | 1977 | 97941 |
| some helminthozoonotic infections in zambia. | parasitic infections constitute an important group of zoonoses. stool examination of inpatients, medical examinees and out-patients in a sub-tropical environment established that inermicapsifer madagascariensis and schistosoma mattheei are occasionally anthropozoonotic in zambia. strongyloides fülleborni, a species normally parasitic in primates is not uncommon in man; whether it is anthropozoonotic or a parasite well adapted to man in this part of africa needs further investigation. the finding ... | 1978 | 97951 |
| comparison of arachnoiditis produced by meglumine iocarmate and metrizamide myelography in an animal model. | myelography in monkeys was performed with either meglumine iocarmate or metrizamide. the severity of resultant arachnoiditis in each animal 12 weeks later was evaluated by repeat myelography and by histologic study of the arachnoid. three of the four animals examined with meglumine iocarmate had severe arachnoiditis; none of the four animals examined with metrizamide had as severe changes. the difference between the two groups was statistically significant (p less than .05). | 1978 | 97964 |
| photoelectric method for estimating hemodynamic changes in regional cerebral tissue. | a new photoelectric method for measuring hemodynamic changes in a thin layer of cerebral tissue in situ is described. the apparatus consists of a miniature lamp of 0.7 mm od and a photodiode with a color filter having maximum light transmission at 548 nm. the lamp was chronically or acutely implanted into the brain tissue of animals as a light source, and the intensity of the light transmitted through the cerebral tissue was monitored with the photodiode from the brain surface. the intensity of ... | 1978 | 98061 |
| effect of staphylococcal enterotoxin b on cardiorenal functions and survival in x-irradiated rhesus macaques. | pretreatment of rhesus macaques with nonlethal total-body x-irradiation (400 r) prolonged survival time from an average of 15 hours to 101 hours after intravenous (iv) inoculation of 50 microgram of staphylococcal enterotoxin b (seb)/kg of body weight. radiation exposure per se did not produce detectable cardiorenal changes; however, the longer survival after seb challenge exposure in x-irradiated rhesus macaques was associated with improved cardiorenal functions if compared with that of nonirra ... | 1978 | 98079 |
| effect of low temperature on growth, viability, and synthesis of mycolic acids of mycobacterium tuberculosis strain h37ra. | cultures of mycobacterium tuberculosis strain h37ra were grownto early logarithmic phase at 37 degrees c and were incubated at 16 degrees, 20 degrees, and 25 degrees c. the decrease in this ability was more rapid at 20 degrees c than at 16 degrees c. low-temperature incubation caused decreases in the ratios of mycolic acids and monounsaturated c16-19 fatty acids relative to the total of fatty acids synthesized. it also caused an increase in the ratio of saturated c24-26 fatty acids relative to ... | 1978 | 98081 |
| microsporidian infection in the cyst wall of trematode metacercariae encysted in fish. | microsporidian infection is reported in liza ramada (risso), mugilidae, from bardawil lagoon, mediterranean coast of sinai, in the fibroblasts of the metacercarial capsule of heterophyes heterophyes (siebold). infection of the metacercarial cyst resulted in an hypertrophy of the cyst wall and degeneration and eventual death of the encapsulated metacercaria. | 1978 | 98090 |
| activity of three 8-hydroxyquinoline derivatives against in vitro dental plaque. | three 8-hydroxyquinoline derivatives, assessed using an in vitro preformed dental plaque model system, were differentially inhibitory for four plaque-forming microorganisms. | 1978 | 98105 |
| in vitro antibacterial activity of amikacin and ticarcillin, alone and in combination, against pseudomonas aerurginosa. | in vitro antimicrobial susceptibility studies using amikacin and ticarcillin, alone and in combination, were performed on 20 strains of pseudomonas aeruginosa. all strains were susceptible to amikacin, and ticarcillin was active against 16 of the 20 strains. enhanced anti-pseudomonas activity could be demonstrated with the combination of amikacin and ticarcillin. | 1978 | 98109 |
| lack of association between human erythrocyte membrane acetylcholinesterase and osmotic fragility. | | 1978 | 98168 |
| effects of mosquito control insecticides on nitrogen fixation and growth of blue-green algae in natural plankton associations. | | 1978 | 98184 |
| analgetic actions of intrathecal opiates in cat and primate. | | 1978 | 98219 |
| cellular uptake, transport, and macromolecular binding of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by human cells in vitro. | | 1978 | 98231 |
| thyroid-stimulating hormone: neuroregulation and clinical applications. part 2. | | 1978 | 98254 |
| relation of nucleosomes to dna sequences. | | 1978 | 98278 |
| progesterone levels in monkeys immunized with pr-beta-hcg-tt after injection of hlh and hcg during luteal phase. | | 1978 | 98288 |
| the handedness of rhesus monkeys: ii. concurrent reaching. | of 171 monkeys tested for handedness, 60 were found to make occasional bilateral concurrent reaches. these reaches accounted for only 1.3% of the total of 600 reaches observed for each animal. younger animals were observed to make such reaches more frequently than older animals. concurrent reaching was characterized by a lower degree of preference for the overall preferred hand than unilateral reaches made by the same animals at comparable periods of testing. | 1978 | 98292 |
| bacterial endocarditis on a prosthetic valve. oral treatment with amoxicillin. | a patient with endocarditis due to streptococcus faecalis on an aortic valvular prosthesis was successfully treated using large oral doses of amoxicillin concurrently with intramuscular administration of streptomycin. oral therapy was employed because of a persistent reaction to intravenously administered antibiotics. oral therapy for bacterial endocarditis occurring on an artificial valve may be attempted as a last resort when all other accepted therapeutic measures have failed. | 1978 | 98296 |
| filarial nodule of the female breast. clinicopathologic study of 57 cases. | | 1978 | 98307 |
| subcortical projections of the dorsomedial visual area (dm) of visual association cortex in the owl monkey, aotus trivirgatus. | the efferent subcortical connections of the dorsomedial cortical visual area (dm) in the owl monkey were determined by tracing degenerating axons following lesions or by tracing axonal pathways following injection of radioactively labeled proline. areas of termination included structures which are known to receive input from many other regions of cortex such as the claustrum, putamen, caudate nucleus, reticular nucleus of the thalamus and pontine nuclei. other terminations were in subcortical st ... | 1978 | 98340 |
| from fallopius to fantasy. | knowledge of the female reproductive system in classical times is reviewed briefly. current knowledge of tubal physiology is explained in greater detail. this knowledge, which is relevant to the study of fertility and sterility, includes sections dealing with: 1) sperm transport; 2) sperm capacitation; 3) fertilization; and 4) ovum and embryo transport. since human data for some of these areas is lacking, data obtained in the study of other species is used as a supplement. although it is now ... | 1978 | 98355 |
| passive immunization with an antibody to the beta-subunit of ovine luteinizing hormone as a method of early abortion--a feasibility study in monkeys (macaca radiata). | antiserum to the beta-subunit of ovine luteinizing hormone (olh-beta) raised in monkeys (macaca radiata) has been tested by a variety of criteria both in vivo and in vitro to establish its ability to neutralize olh, hlh, and human chorionic gonadotropin (hcg). passive administration of this antiserum caused inhibition of ovulation and termination of pregnancy in recipient monkeys as indicated by premature vaginal bleeding and a significant reduction in serum progesterone and estrogen levels. the ... | 1978 | 98358 |
| [method of remote orthogonal ecg and vcg recording in monkeys]. | | 1978 | 98360 |
| pre-immunization and post-exposure treatment with inactivated rabies vaccine of chick embryo cell culture origin (cec). | routine laboratory assay revealed that the potency of concentrated rabies vaccine of chick embryo cell culture (cec) origin was in the same level compared with suckling mouse brain (smb) vaccine. over one hundred persons received two doses of cec vaccine at an interval of one week and produced high level of neutralizing antibody against rabies virus. the monkeys experimentally infected with street rabies virus were satisfactorily protected by subcutaneous inoculation with cec vaccine one hour af ... | 1978 | 98373 |
| a pharmacologic profile of mcn-3495 [n-(1-methyl-2-pyrrolidinylidene)-n'-phenyl-1-pyrrolidinecarboximidamide], a new, orally effective hypoglycemic agent. | mcn-3495, a new compound unrelated strucuturally to the sulfonylureas or phenformin, has been found to produce a hypoglycemic effect in nondiabetic rats, dogs, mice, and monkeys. the minimum effective dose of mcn-3495 that lowers fasting blood glucose and improves glucose tolerance was found to be about 2.5 to 5 mg-per kilogram, per os, except in fasted monkeys, in which a tenfold greater potency was observed. when mcn-3495 was given repeatedly for three to five days, no tolerance to the hypogly ... | 1978 | 98377 |
| effects of dihydroegocristine on glucagon induced lipolysis and insulin release in man. | | 1978 | 98422 |
| a device for chronic access to brain in conscious monkeys. | | 1978 | 98436 |
| experimental fractures of monkey mandibles. | forty vervet monkey half mandibles, 20 with unerupted third molars and 20 with erupted third molars, were partially embedded in acrylic and loaded in an instron tensiometer. mandibles with unerupted third molars fractured at 15.8 +/- 2.5 kg while those having erupted third molars fractured at 26.4 +/- 4.2 kg. mandibles having unerupted third molars were shown to be significantly weaker than the mandibles with erupted third molar (t = 8.45, p less than 0.001). | 1978 | 98455 |
| biochemical effects on radioprotective agents on the liver microsomal hydroxylating system: in vitro studies. | the action of two radioprotectors--cysteamine and cystamine--on the liver microsomal multi-enzyme hydroxylating system, a key stem in drug and biological compounds metabolism, has been studied. their effects have been systematically analysed at the level of individual enzyme activities and global functions. the two compounds are quite inactive on nadph and nadh cytochrome c reductase activities, but slightly denature the cytochrome p450 into cytochrome p420. furthermore, they do inhibit to some ... | 1978 | 98466 |
| immunopathology of malaria. | | 1978 | 98476 |
| pleiotropic effect of a rifampin-resistant mutation in bacillus subtilis. | rifampin-resistant (rifr) mutants were isolated spontaneously from bacillus subtilis strain 168. a fraction of the mutants did not grow on a minimal medium. a high concentration of one of the l-amino acids (glutamic acid, glutamine, arginine, proline, aspartic acid, or asparagine) was required to restore their growth on the medium. further analysis of one of the mutants (strain rf 161) suggested that the mutant is unable to use ammonia as a nitrogen source and requires amino acids instead. activ ... | 1978 | 98517 |
| formylation of initiator trna methionine in procaryotic protein synthesis: in vivo polarity in lactose operon expression. | eucaryotic and procaryotic organisms differ in two aspects of their translation machinery: polycistronic messengers are expressed as a sequence of individual proteins only in procaryotes, and the initiation of protein synthesis proceeds with an initiator trna which is found to be modified (formylated) in procaryotes and not in eucaryotes. in the present study, we show that formylation is required in vivo for the coordinate expression of the escherichia coli lactose operon. our experiments are co ... | 1978 | 98518 |
| evidence that the regulation of diphtheria toxin production is directed at the level of transcription. | it has been known for several decades that iron inhibits the production of diphtheria toxin by corynebacterium diphtheriae by preventing expression at maximal levels. we examined the inhibition kinetics of toxin production after the addition of either iron or rifampin to iron-limited cultures of c7 (betatox+). iron-mediated inhibition of toxin production was found to be linear within the range of 16 nm to 16 micron. the inhibition kinetics following the addition of iron or rifampin was almost id ... | 1978 | 98519 |
| altered mrna metabolism in ribonuclease iii-deficient strains of escherichia coli. | the metabolism of mrna from the lactose (lac) operon of escherichia coli has been studied in ribonuclease (rnase) iii-deficient strains (rnc-105). the induction lag for beta-galactosidase from the first gene was twice as long, and enzyme synthesis was reduced 10-fold in one such mutant compared with its isogenic rnc+ sister; in the original mutant strain ab301-105, synthesis of beta-galactosidase was not even detectable, although transduction analysis revealed the presence of a normal lac operon ... | 1978 | 98520 |
| isolation of immunoglobulin from splenic lymphocytes of inbred rats by triton x-100 solubilization. | | 1978 | 98589 |
| quantitative determination of the serum antibody response to the capsular polysaccharide of bacteroides fragilis subspecies fragilis in women with pelvic inflammatory disease. | the antibody response to the capsular polysaccharide of bacteroides fragilis subspecies fragilis in women with acute pelvic inflammatory disease was quantitated using a sensitive radioactive antigen-binding assay. antibody detected by this technique correlated highly with antibody measured by quantitative precipitin analysis (r = 0.99). paired acute- and convalescent-phase sera obtained from women from whom b. fragilis subspecies fragilis was isolated by culdocentesis showed significantly greate ... | 1978 | 98597 |
| antibacterial functions of macrophages in experimental protein-calorie malnutrition. i. description of the model, morphologic observations, and macrophage surface igg receptors. | an experimental protein-calorie malnutrition was produced in weanling sprague-dawley rats. the model resembles human malnutrition with respect to weight loss, inanition, angular stomatitis, anemia, lymphopenia, hypoproteinemia with hypoalbuminemia, and marked thymic involution. in addition, systemic invasion by gram-negative rods was documented. however, no edema was produced, and animals did not survive for longer than six weeks on the protein-deficient diet. one percent glycogen was found to b ... | 1978 | 98598 |
| circadian variations in cortisol concentrations in the plasma of female rhesus monkeys. | | 1978 | 98605 |
| physiological disposition and biotransformation of l-alpha-[2-3h]acetylmethadol (laam) in acutely and chronically treated monkeys. | | 1978 | 98628 |
| experimental injury of the optic nerve with optic disc swelling. | an ultrastructural study utilizing horseradish peroxidase was performed to determine the mechanism and consequences of leakage of vascular protein following injury of the optic nerve. unilateral optic nerve injuries were produced in four rhesus monkeys by making a cautery lesion on the retrobulbar portion of the optic nerve. optic disc changes were followed with stereo fundus photography and fluorescein angiography. three to 14 days after injury horseradish peroxidase was given intravenously and ... | 1978 | 98667 |
| molecular cloning of the gene region coding for the chloroplast rrna of euglena gracilis. | e. gracilis chloroplast dna bam fragments e and d, coding for rrna were cloned separately using the plasmid pbr 322 as vector and e. coli as host. the newly constructed recombinant plasmids egcks 8 and egcks 11 (containing the bam hi fragments e and d respectively) were analysed and characterized by gel electrophoresis, electronmicroscopy and analytical ultracentrifugation. | 1978 | 98702 |
| the effect of thyrotropin-releasing hormone (trh) and somatostatin (ghrih) on growth hormone and prolactin secretion in vitro and in vivo in the domestic fowl (gallus domesticus). | the effects of thyrotropin-releasing hormone (trh) on growth hormone (gh) and prolactin (prl) secretion have been investigated in vitro and in vivo in domestic fowl. in both conscious and anaesthetized immature chickens the administration (i.v.) of trh (2.5 and 25 microgram/kg) significantly increased the concentration of plasma gh. the simultaneous administration of somatostatin (ghrih), 2.5 microgram/kg, to conscious birds significantly reduced the magnitude of the gh response to trh treatment ... | 1978 | 98725 |
| electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey. | | 1978 | 98733 |
| changes in composition of tears of malnourished children. | | 1978 | 98738 |
| reduced hepatic bilirubin uridine diphosphate glucuronyl transferase and uridine diphosphate glucose dehydrogenase activity in the human fetus. | hepatic bilirubin uridine diphosphate glucuronyl transferase (udpg-t) activity was 0.14 and 0.22 units in two fetuses aged 17 and 22 weeks, respectively, and less than 0.1 unit in 15 fetuses, aged 8--19 weeks compared to 0.68--1.99 units in 21 normal adults. hepatic uridine diphosphate glucose dehydrogenase (udpg-d) activity in 14 fetuses, aged 8--18 weeks, ranged from 6.2--15.0 units (mean = 11.3 +/- 0.7) compared to 28.8--49.2 units (mean = 39.6 +/- 2.5) in eight normal adults (p less than 0.0 ... | 1978 | 98749 |
| effect of dopamine on renal blood flow of baboon in endotoxin shock. | renal vasodilation observed in canine endotoxemia did not occur during endotoxin shock in the baboon: in fact, renal artery blood flow was markedly reduced. infusion of dopamine in the baboon restored the renal artery blood flow. | 1978 | 98752 |
| studies on the occurrence of peptococcus indolicus and corynebacterium pyogenes in abscesses in swine, and on the occurrence of pc. indolicus in apparently normal skin and mucous membranes of piglets. | pc. indolicus was isolated from 42.7% and cb. pyogenes from 48.7% of 150 pus-samples from abscesses in pigs (slaughter-house material, table i). in 41 specimens the two organisms were found together. further, pc. indolicus was demonstrated in 22.4% of 290 swabs from apparently normal skin and mucous membranes of piglets (autopsy material, table ii). by gel diffusion analysis the strains of pc. indolicus were referred to the serotypes b, c, d, e, or f. the type distribution (table iii) possibly r ... | 1978 | 98755 |
| critical factors in the quality control of antilymphocyte globulin (alg). | | 1977 | 98763 |
| induced cell aggregation and mating in streptococcus faecalis: evidence for a bacterial sex pheromone. | recipient strains of streptococcus faecalis produce a trypsin sensitive, heat resistant, nuclease resistant factor, designated clumping-inducing agent (cia) which causes strains carrying certain conjugative plasmids to aggregate. rna and protein synthesis but not dna synthesis are required for aggregation to occur. recipient filtrates that contain cia activity also induce donors to mate at high frequencies. introduction of a transferable plasmid into strains producing cia dramatically reduces th ... | 1978 | 98769 |
| [anemias secondary to parasitosis]. | | 1978 | 98817 |
| vascular dynamics of an experimental cerebral arteriovenous shunt in the primate. | an arteriovenous fistula which shunted arterial blood from the circle of willis to the internal jugular vein was created in ten monkeys. continued patency of the shunt was confirmed angiographically. cerebral blood flow measurements were then obtained with the shunt both open and occluded. flow was also determined in response to elevations of systemic arterial pressure and raised arterial carbon dioxide tensions (paco2), again with the shunt both patent and occluded. in addition, flow through th ... | 1978 | 98854 |
| experimental spinal cord trauma, ii: blood flow, tissue oxygen, evoked potentials in both paretic and plegic monkeys. | graded clinical motor deficits were produced in a series of rhesus monkeys subjected to experimental spinal cord trauma from a variety of impact loads. an argon washout technique was used to measure spinal cord blood flow; tissue oxygen carbon dioxide, and somatosensory evoked potentials (seps) were also monitored. each animal received a clinical grade and, after a week of study, the spinal cords were removed for histopathological grading. blood flow in paraplegic animals was significantly decre ... | 1978 | 98856 |