| cardiac sympathetic nerve activity and heart rate during coronary occlusion in awake cats. | responses in efferent cardiac sympathetic nerve activity (csna) and heart rate (hr) to a 100-s anterior descending coronary artery occlusion were measured in cats under awake, atropinized, anesthetized, or anesthetized and atropinized states. in the conscious state, at 20 and 90 s of occlusion, csna increased by 23% and then decreased by 7%, respectively, whereas hr decreased by 5 and 17%, respectively. with atropinization and/or anesthesia, the initial increase in csna was inhibited and the lat ... | 1986 | 3752267 |
| effect of allopurinol on caffeine disposition in man. | caffeine (5 mg kg-1) was administered orally to two healthy, non-smoking subjects on three separate occasions--before, and during therapy with the xanthine oxidase inhibitor allopurinol at doses of either 300 or 600 mg daily. plasma and urinary levels of methylxanthines, endogenous oxypurines and allopurinol and its metabolite oxypurinol were measured using h.p.l.c. analyses. allopurinol treatment caused a specific, dose-dependent inhibition of the conversion of the caffeine metabolite 1-methylx ... | 1986 | 3754760 |
| tryptone-yeast extract broth as a culture medium for haemophilus pleuropneumoniae and haemophilus parasuis to be used as challenge inocula. | haemophilus pleuropneumoniae and haemophilus parasuis were grown in a liquid medium containing tryptone and yeast extract. whereas culture turbidity during exponential growth of either organism was proportional to the number of viable cells, continued incubation of stationary phase cultures was accompanied by a dramatic decrease in viability with no corresponding decrease in culture turbidity. it is concluded that the medium described should prove useful for the growth of porcine haemophili for ... | 1986 | 3755642 |
| immunologic relationships among haemophilus pleuropneumoniae strains of serovar 1 to 5 in guinea pigs. | | 1986 | 3761782 |
| effect of pasteurella multocida and haemophilus pleuropneumoniae toxins on swine alveolar macrophages. | supernatants were obtained from 18 hr. broth cultures of pasteurella multocida strains d82 and d62 (serotype d, toxigenic), kobe 6 (type d, non-toxigenic), a50 and x73 (type a, non-toxigenic), haemophilus pleuropneumoniae serotypes 1, 5 and 6, haemophilus sp. taxon "minor group" (2 strains) and an avirulent serotype 1 strain of h. pleuropneumoniae. the supernates were filtered, ph-neutralized and tested for cytotoxicity after incubation for 18 hours in the presence of swine alveolar macrophage m ... | 1986 | 3765367 |
| structural studies of the capsular polysaccharide from haemophilus pleuropneumoniae serotype 1. | the capsular polysaccharide of haemophilus pleuropneumoniae serotype 1 (atcc 27088) was found to be a teichoic acid type polysaccharide of a repeating disaccharide unit composed of 2-acetamido-2-deoxy-d-glucose and d-galactose units. by composition analysis, methylation, partial hydrolysis, dephosphorylation, and one- and two-dimensional 500-mhz proton nuclear magnetic resonance experiments, together with 13c nuclear magnetic resonance studies, it was concluded that the capsular polysaccharide i ... | 1986 | 3768164 |
| purification and characterization of adenine phosphoribosyltransferase from mouse mammary carcinoma fm3a cells in culture. | adenine phosphoribosyltransferase has been purified to apparent homogeneity from mouse mammary tumor fm3a cells. the purified enzyme, with a specific activity of 20.6 x 10(6) units/g protein at 30 degrees c, was homogeneous as judged by polyacrylamide gel electrophoresis and ouchterlony double immunodiffusion analysis. the native enzyme had a molecular weight of 44,000 and a subunit composition of 23,000. apparent km values for adenine and 5-phosphoribosyl-1-pyrophosphate (prib-pp) were 6.6 micr ... | 1986 | 3768421 |
| vaccine potential of haemophilus pleuropneumoniae oligosaccharide-tetanus toxoid conjugates. | oligosaccharides of smooth-type lipopolysaccharide (lps) and oligosaccharides of rough-type lps were isolated from haemophilus pleuropneumoniae and conjugated to tetanus toxoid by reductive amination. the antigenic and immunogenic characteristics of the oligosaccharides, the oligosaccharide-tetanus toxoid conjugates, and the lps of h. pleuropneumoniae were determined by passive hemagglutination, enzyme-linked immunosorbent assay, and inhibition enzyme-linked immunosorbent assay with antisera pro ... | 1986 | 3770954 |
| quantification by flow microfluorimetry of specific binding of antibody to some serotypes of haemophilus pleuropneumoniae. | the cross-reactivity exhibited in various other serological procedures by antisera prepared against some standard laboratory strains representing serotypes 1 to 4 and 6 of haemophilus pleuropneumoniae was also apparent when they were examined by flow microfluorimetry. | 1986 | 3775120 |
| protective efficacy of capsule extracts of haemophilus pleuropneumoniae in pigs and mice. | capsular extracts of haemophilus pleuropneumoniae, serotype 1, were mixed with al(oh)3 gel (3 parts extract + 1 part al(oh)3) and used as vaccines in pigs and mice. four preparations were tested in experiment i: nacl and cetavlon (hexadecyltrimethyl ammonium bromide) extracts of both low in vitro passage (lp) and high in vitro passage (hp) culture, respectively. four pigs vaccinated with the nacl extract of the lp strain survived, whereas one of four from each of the remaining vaccine groups and ... | 1986 | 3776093 |
| bacteriological, serological, and pathological examinations of haemophilus pleuropneumoniae infection in 200 slaughtered pigs. | | 1986 | 3784229 |
| growth and hemolysin production by haemophilus pleuropneumoniae cultivated in a chemically defined medium. | a chemically defined medium (cdm) has been developed which supports both growth and hemolysin production by haemophilus pleuropneumoniae. although the growth rate in stationary cultures was substantially slower in cdm than in trypticase soy broth plus 0.6% yeast extract (tsbye) and slightly slower than in heart infusion broth (hib), extracellular hemolysin activity in cdm was slightly higher than in hib and 16-fold greater than in tsbye. maximum hemolytic activity was produced in cdm in early to ... | 1986 | 3791049 |
| differential effect of plasma protein binding of bupivacaine on its in vivo transfer into the brain and salivary gland of rats. | the effect of plasma protein binding of bupivacaine on its transfer into brain and salivary gland was studied using bovine serum albumin, human alpha 1-acid glycoprotein (aag) and human serum. the in vivo brain extraction and salivary gland extraction of [3h] bupivacaine relative to [14c]butanol were determined with an intracarotid injection technique used on rats. the brain extraction varied inversely with the bovine serum albumin (0-7.5%) and aag (0-3.0 mg/ml) concentrations. the salivary extr ... | 1986 | 3795038 |
| intravascular macrophages in lungs of pigs infected with haemophilus pleuropneumoniae. | pigs were inoculated intratracheally with a virulent or an avirulent isolate of haemophilus pleuropneumoniae serotype 5 and sacrificed during the first 24 hours post-inoculation. intravascular macrophages were examined by electron microscopic and morphometric techniques. samples of lung were taken from regions with no macroscopic lesions (zone 0), 2.5 to 3.0 cm from lesions (zone 1), and from the immediate edge of lesions (zone 2). those pigs inoculated with the avirulent isolate did not develop ... | 1986 | 3811134 |
| influence of inoculation sites and tumor cell culture techniques on the phenotype of a mixed cartilage- and bone-producing mouse mammary tumor. | we have previously reported the characterization of an intraperitoneally (ip) transplantable bone-forming mxt tumor. however, the question was unresolved as whether the bone-forming cells originated from either the host animal or from the neoplasm itself. the present work attempts to answer this question by studying the influences of inoculation sites (subcutaneously, sc; intraperitoneally, ip; in the brain, ib; intracranially, icr) on both the cartilage- and bone-forming tumor phenotypes. furth ... | 1986 | 3813489 |
| similarity principles and intrinsic geometries: contrasting approaches to interspecies scaling. | we criticize standard allometric approaches on the grounds that they emphasize scaling to one variable at a time, whereas chemically reactive hydrodynamic systems involved in pharmacokinetic phenomena are of higher dimension. we show that attempts based on mechanical similitude to set a dosage that would be equivalent across species (for example, from mouse to humans) lead to ambiguous results. another failing of standard allometry may be its incapability to accommodate the neoteny of homo sapie ... | 1986 | 3820095 |
| effect of heat treatment on the surface antigens of haemophilus pleuropneumoniae. | coagglutination and ring precipitation tests were used to study the effect of heat on the surface antigens of haemophilus pleuropneumoniae strains employing the reference strains belonging to serotypes 1 to 7 and field isolates belonging to serotypes 1, 2, 3, 5, 6 and 7. by immunising rabbits with formalin-fixed whole-cell suspension, antibodies were obtained which sensitised cowan i staphylococcus aureus to coagglutinate antigen preparations which had not been heated, or heated at 56 degrees c, ... | 1987 | 3824843 |
| an evaluation of agglutination and coagglutination techniques for serotyping of haemophilus pleuropneumoniae isolates. | a comparative evaluation of rapid slide agglutination, tube agglutination, 2-mercaptoethanol tube agglutination, and coagglutination tests was made for serotyping isolates of haemophilus pleuropneumoniae. the results indicated that a majority of the isolates could be serotyped by any of these tests. but, it was not uncommon to find isolates which were inagglutinable or poorly agglutinable in homologous sera. heat treatment of whole-cell suspensions of such isolates was essential to unmask the se ... | 1987 | 3826860 |
| serological characterization of haemophilus pleuropneumoniae (actinobacillus pleuropneumoniae) strains and proposal of a new serotype: serotype 10. | | 1985 | 3836574 |
| reflexions on craniofacial growth research. | | 1985 | 3837988 |
| synthesis and beta-lactamase inhibitory properties of 2 beta-[(acyloxy)methyl]-2-methylpenam-3 alpha-carboxylic acid 1,1-dioxides. | p-nitrobenzyl 2 beta-[(benzoyloxy)methyl]-2 alpha-methylpenam-3 alpha-carboxylate was prepared by reaction of p-nitrobenzyl 2-[2-oxo-3 alpha-bromo-4-(benzothiazol-2-yldithio)azetidin-1-yl] -2-isopropenylacetate with silver benzoate in the presence of iodine. the resulting diester was oxidized to the sulfone with potassium permanganate and hydrogen peroxide, and the bromine and p-nitrobenzyl groups were removed by hydrogenolysis to give potassium 2 beta-(benzoyloxy)methyl 2 alpha-methylpenam-3 al ... | 1985 | 3872369 |
| the enteric neural receptor for 5-hydroxytryptamine. | an enteric neural receptor for serotonin (5-ht) has been characterized. this receptor was assayed, using 3h-5-ht as a radioligand, by rapid filtration of isolated enteric membranes and by radioautography. in addition, intracellular recordings were made from ganglion cells of the myenteric plexus. high affinity, saturable, reversible, and specific binding of 3h-5-ht was demonstrated both to membranes of the dissected longitudinal muscle with adherent myenteric plexus and the mucosa-submucosa. rad ... | 1985 | 3874089 |
| [familial transmission of deleted chromosome 22 [r(22)p0?] in two normal women]. | a deleted chromosome 22 resembling a ring chromosome was found in a 27-year-old woman without dysmorphic features nor mental retardation. a similar chromosome was found in her mother. | 1985 | 3876060 |
| serotyping of haemophilus pleuropneumoniae by rapid slide agglutination and indirect fluorescent antibody tests in swine. | one hundred and forty-one isolates of haemophilus pleuropneumoniae from iowa and illinois swine were characterized morphologically and biochemically and serotyped by rapid slide agglutination (rsa) and indirect fluorescent antibody (ifa) tests. hyperimmune antisera were produced in rabbits using inactivated whole-cell suspensions of the reference strains for h pleuropneumoniae serotypes 1 to 7 and strain 202, representing the taxon "minor group." cross testing of the reference strains and refere ... | 1985 | 3882026 |
| treatment of hypertension in renal disease. | experimental and clinical evidence are summarized that support the hypothesis that enhanced transmission of systemic hypertension to the adapted glomerulus in the setting of reduced nephron mass may be responsible for accelerated vascular and glomerular damage in the hypertensive stage of parenchymal renal disease in man. in experimental models of hypertension associated with reduced renal mass, the kidney appears to be damaged directly by transmission of pressure rather than primarily through v ... | 1985 | 3887904 |
| insulin reversal of cancer cachexia in rats. | the anabolic effects of exogenous neutral protamine hagedorn insulin on tumor-bearing (tb) and non-tumor-bearing (ntb) rats were examined. exogenous insulin (2 units/100 g/day) produced similar hypoglycemia in tb and ntb rats. food intake and body weight gain were significantly increased by insulin in ntb rats. in tb rats in an early stage of cachexia, insulin increased food intake and host weight (total body weight minus tumor weight). in tb rats with severe cachexia, insulin increased food int ... | 1985 | 3896470 |
| [active metabolites of anti-arrhythmia drugs]. | | 1985 | 3900963 |
| [active metabolites of anti-arrhythmia drugs]. | | 1985 | 3900963 |
| serological cross-reactivity between a porcine actinobacillus strain and haemophilus pleuropneumoniae. | during serological screening of a closed spf-herd free of pleuropneumonia, more than half of the pigs were positive for complement-fixing antibodies to haemophilus pleuropneumoniae. actinobacillus bacteria closely related to a. suis were isolated from tonsillar tissue of 14 out of 20 slaughtered pigs submitted for pathological and bacteriological evaluation. none of the pigs had evidence of respiratory disease. two pigs inoculated endobronchially with a selected actinobacillus strain developed m ... | 1985 | 3926287 |
| biochemical and serological identification of strains of haemophilus pleuropneumoniae. | eighteen field isolates of haemophilus pleuropneumoniae were studied biochemically and serotyped using the complement fixation test (cft), agglutination test and the immunodiffusion test. three biochemical tests (v-dependency, camp-reaction and urease activity) were found to be very useful for the biochemical characterization of the h. pleuropneumoniae. haemolysis on blood agar plates, although present, was not sufficiently pronounced in all cases to warrant absolute dependence on this character ... | 1985 | 3929457 |
| synthesis of dihomoprostaglandins from adrenic acid (7,10,13,16-docosatetraenoic acid) by human endothelial cells. | human umbilical vein endothelial cells were found to contain adrenic acid (22:4) in their cellular lipids. since this fatty acid may be metabolized by cyclooxygenase in the kidney, the metabolism of adrenic acid was studied in endothelial cell cultures. [14c]adrenic acid was metabolized to several more polar metabolites. two of these metabolites co-migrated on hplc with 1 alpha,1 beta-dihomo-8-ketoprostaglandin f1 alpha (the metabolite of 1 alpha, 1 beta-dihomoprostaglandin i2) and 1 alpha,1 bet ... | 1985 | 3931686 |
| gastric mucosal damage in sepsis--effects of pretreatment with a synthetic prostaglandin e1 analogue. | an experimental model was used which includes intragastric instillation of 80 mm hcl and 0.6 ml bile/kg followed by intravenous infusion of live e coli in cats for up to three hours. this procedure regularly induces gastric mucosal ulcerations. mucosal blood flow was measured by microspheres before, early, and late in sepsis. total gastric blood flow was recorded electromagnetically. mucosal regeneration capacity as reflected by the rna/dna ratio was measured. misoprostol (a pge1 analogue) was i ... | 1985 | 3932138 |
| serological characterization of haemophilus pleuropneumoniae (actinobacillus pleuropneumoniae) strains and proposal of a new serotype: serotype 9. | | 1985 | 3939175 |
| morphological and biochemical comparison of virulent and avirulent isolates of haemophilus pleuropneumoniae serotype 5. | capsular structure and biochemical composition varied between two isolates (virulent and avirulent) of haemophilus pleuropneumoniae serotype 5. the presence of capsule was determined by transmission electron microscopy with glutaraldehyde-osmium, ruthenium red, alcian blue, and phosphotungstic acid staining procedures. the virulent isolate of h. pleuropneumoniae had a distinct, adherent capsule. the avirulent isolate had a fragile, easily removed capsule. capsular material (cm) and a lipopolysac ... | 1986 | 3943895 |
| isolation, purification, and partial characterization of a lipopolysaccharide from haemophilus pleuropneumoniae. | lipopolysaccharide (lps) from haemophilus pleuropneumoniae 1536, serotype 2, was isolated and purified by a procedure designed to be equally satisfactory for both smooth- and rough-type lps. the lps yield was 53%. analysis of the preparations revealed that protein, nucleic acid, and cellular phospholipid contamination was negligible (less than 0.1%). analysis of the sugar content of the lps by gas-liquid chromatography and colorimetric analysis revealed the presence of rhamnose, mannose, galacto ... | 1986 | 3943899 |
| interaction between heat-stable hemolytic substance from haemophilus pleuropneumoniae and porcine pulmonary macrophages in vitro. | cytocidal and anti-phagocytic effects of the heat-stable hemolytic substance produced in culture supernatant by haemophilus pleuropneumoniae serotype 2 on porcine pulmonary macrophages (pmp) were investigated in vitro. the substance was partially purified by sucrose density gradient ultracentrifugation, and it seems to be a carbohydrate. the partially purified preparation of the heat-stable carbohydrate with hemolytic activity was used as h. pleuropneumoniae hemolysin throughout this study. viab ... | 1986 | 3943901 |
| a functional organization of on and off pathways in the rabbit retina. | intracellular electrophysiological recordings were obtained from amacrine and ganglion cells in an isolated, superfused retina-eyecup preparation of the rabbit. cells were characterized physiologically, after which cell-staining was accomplished by intracellular iontophoresis of hrp. a computer-assisted image-processing system was used to study the dendritic stratification pattern of hrp-labeled neurons within the inner plexiform layer (ipl). our results support the concept that the ipl is funct ... | 1986 | 3944611 |
| complement activation and adult respiratory distress syndrome during intermittent flow apheresis procedures. | we observed complement (c) activation during intermittent flow apheresis procedures (haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ards). actual c3 conversion during apheresis was illustrated by the finding of significantly elevated c3d levels (p less than 0.05) and of significantly increased alpha-1-antitrypsin/c3 ratios (p less than 0.05) in postapheresis serums. similarly, marked granulocyte aggregating activity was found in these serums, i ... | 1986 | 3946010 |
| detection of haemophilus pleuropneumoniae antigens using the coagglutination test. | | 1986 | 3962114 |
| incidence, economic effects, and control of haemophilus pleuropneumoniae infections in pigs. | this thesis synopsis reports the results of investigations on: the incidence of clinical and subclinical h. pleuropneumoniae infections on pig farms in north brabant; the economic loss on fattening farms; the effect of husbandry; the possibility of eradicating h. pleuropneumoniae on infected breeding farms on the basis of serological testing; the possibility of control on fattening farms by means of vaccination. the principal findings were as follows: clinical and subclinical h. pleuropneumoniae ... | 1986 | 3962149 |
| mesothelial healing: morphological and kinetic investigations. | by using structural, kinetic and irradiation techniques it is possible to show that mesothelial healing is a local event. initially, macrophages occupy the surface of a wound on the injured visceral layer, while mesothelial proliferation proceeds at the edge of the wound and the opposing parietal surface. fibrin is formed on the wound surface within 24 h, even in the absence of much haemorrhage. mesothelial ingrowth begins with isolated cells migrating from the wound edge as well as from the ser ... | 1985 | 3973769 |
| metastatic nontraumatic clostridium septicum osteomyelitis. | nontraumatic clostridial infections are rare, but need to be diagnosed and treated early or high morbidity and mortality rates result. we believe that this is the first reported case of metastatic nontraumatic clostridium septicum osteomyelitis. early treatment with surgical debridement and parenteral antibiotics without hyperbaric oxygen was used. an associated occult rectal malignancy was discovered and treated. | 1985 | 3980945 |
| comparative virulence of porcine haemophilus bacteria. | the virulence of strains of haemophilus pleuropneumoniae serotype 1, 2, 3, 7 and strains of the "minor-group" and haemophilus parasuis were compared by inoculating specific pathogen-free pigs into the lower airways with specified doses of bacteria. haemophilus pleuropneumoniae, strain w, serotype 1, given in 1 x 10(8) colony-forming units, produced a lethal acute pleuropneumonia in four pigs. nonlethal localized pulmonary necrosis was induced in four groups of two pigs given 1 x 10(7), 1 x 10(6) ... | 1985 | 3986682 |
| pulmonary artery wedge pressure may fail to reflect left ventricular end-diastolic pressure in dogs with oleic acid-induced pulmonary edema. | we investigated the accuracy with which pulmonary artery wedge pressure (wp) reflected left ventricular end-diastolic pressure (lvedp) in dogs with oleic acid-induced pulmonary edema. we compared hemodynamic variables before and during edema, as measured from a pulmonary artery catheter placed before oleic acid (pa-1) and from a second catheter (pa-2) placed 2 h after oleic acid infusion. oleic acid decreased arterial oxygen saturation and cardiac output and increased pulmonary vascular resistan ... | 1985 | 3996001 |
| [studies on the mechanism of the estrogen action in human breast cancer]. | only some 50% of estrogen receptor positive breast cancer patients respond to hormone therapy. it is possible that the mechanism of the estrogen action is disturbed in malignant cells. in order to determine which steps of the mechanism are disturbed, cytoplasmic estrogen and progesterone receptor and nuclear estrogen receptor were studied in 217 cases of human breast cancer. thirty breast cancer tumors were examined for nuclear translocation of estradiol in vitro. the assessment of the transloca ... | 1985 | 3999388 |
| efficacy of haemophilus pleuropneumoniae vaccine in pigs. | | 1985 | 4010122 |
| development of an experimental animal model for the protection test of haemophilus pleuropneumoniae vaccine. | | 1985 | 4010126 |
| [problems of liability in the treatment of colic]. | | 1985 | 4012783 |
| [shared antigens between bcg and tumor cells--immunotherapy with bcg for mouse tumor]. | cytotoxic activity of anti-bcg rabbit serum (a-bcg) and the antigenic relationship between bcg and tumor cells were studies. a-bcg showed high cytotoxic activity against line 10 tumor cells of guinea pig strain 2 and colon 26 tumor cells of balb/c mouse but not to cells of human bladder cancer (ht 1197, ht 1376). cell-killing activity of a-bcg against line 10 and colon 26 was dependent on complement participation. it was also found that colon 26 cells were heterogenous in their susceptibility to ... | 1985 | 4015119 |
| basal firing rate of rat locus coeruleus neurons affects sensitivity to ethanol. | intracellular recordings were made from spontaneously active rat locus coeruleus (lc) neurons in a totally submerged brain slice preparation. bath application of ethanol (etoh) (1-60 mm) inhibited the spontaneous firing of lc neurons. these etoh concentrations are equal to or below etoh concentrations found in the brain during mild to moderate intoxication. the basal frequency of spontaneous firing of lc neurons ranged from 0.4-7 hz. for 9 lc neurons which showed complete block of firing by etoh ... | 1985 | 4015846 |
| microorganisms associated with pneumonia in slaughter weight swine. | the lungs of 334 pigs were obtained from two slaughter plants in minnesota and examined in detail. macroscopic and microscopic evaluation, direct fluorescence for mycoplasma hyopneumoniae and bacterial culture were done on all of them and a subsample of 50 were selected for virus culture. mycoplasma hyopneumoniae, pasteurella multocida and haemophilus spp. were detected in 24.0%, 34.1% and 27.0% of the lungs, commonly in conjunction with each other. one isolate of haemophilus pleuropneumoniae se ... | 1985 | 4016578 |
| comparison of tissue reactions produced by haemophilus pleuropneumoniae vaccines made with six different adjuvants in swine. | tissue damage caused by six different adjuvants incorporated in a haemophilus pleuropneumoniae vaccine was compared in swine. the adjuvants compared were four mineral oil compounds, one peanut oil compound and aluminum hydroxide. inoculations were given in the neck, quadriceps and semitendinosus muscles. the mineral oil adjuvants were highly irritant and caused extensive areas of granulomatous inflammation that were present at eight weeks after injection. the aluminum hydroxide produced smaller ... | 1985 | 4016580 |
| synthesis and quality control of 99mtc-p-butyl ida. | a procedure is described for synthesis of p-butyl ida and for identification of the product by i.r. and nmr spectroscopy and by chemical analysis. a method for preparing this compound by "instant" technique and for its labelling with 99mtc is also given, as well as a procedure for control of the chemical and biological properties of the radiopharmaceutical. radiochemical study shows a high labelling yield of 95%. investigation of the biodistribution proves that this preparation is a good hepatob ... | 1985 | 4018899 |
| hypertension during chronic peripheral and central infusion of angiotensin iii. | recent studies have suggested that the angiotensin ii (ang ii) metabolite [des-asp]ang ii (ang iii) may be nearly equipotent with the parent compound in causing several acute neural responses known to be stimulated by angiotensin peptides (i.e., drinking, augmentation of sympathetic neurotransmission, and centrally mediated pressor responses). because neural actions of ang ii are thought to contribute importantly to the ability of this hormone to cause chronic hypertension, the purpose of the pr ... | 1985 | 4025541 |
| cardiopulmonary effects of hypertonic saline in canine oleic acid-induced pulmonary edema. | vasoactive drugs may increase intrapulmonary shunt in patients with permeability edema. because 7.5% hypertonic saline solution has cardiotonic properties, we studied its hemodynamic and pulmonary effects in a canine model of oleic acid-induced lung injury. immediately after saline infusion, there were increases in cardiac output (2.0 +/- 0.1 to 3.4 +/- 0.2 l/min; p less than .001) and intrapulmonary shunt (50.3 +/- 4.4 to 57.3 +/- 3.2%; p less than .01) without alteration in arterial or mixed v ... | 1985 | 4028751 |
| duration of the complement-fixation antibodies induced in pigs and guinea pigs by haemophilus pleuropneumoniae vaccine. | | 1985 | 4032939 |
| the effects of hypolipidaemic benzodiazepines on serum lipoproteins in hyperlipidaemic rats. | | 1985 | 4037206 |
| compensatory mechanisms in response to an elevated hepatic oxygen consumption in chronically ethanol-fed rats. | during conditions that elevate hepatic oxygen consumption (vlo2), oxygen delivery, or oxygen extraction may also increase, acting as compensatory mechanisms. vlo2 was quantitated by an in vivo method in chronically ethanol-fed rats to establish whether vlo2 was increased and what compensatory mechanisms might ensue. vlo2 was increased 45% (0.32 +/- 0.02 ml o2 x min-1 x 100 g body wt-1; p less than 0.001) in rats chronically fed ethanol for 8 wk, while vlo2 (0.28 +/- 0.04; p = ns) was not increas ... | 1985 | 4039538 |
| morphological features of lamina v neurons receiving nociceptive input in cat sacrocaudal spinal cord. | thirty-six neurons from laminae iii-vii in cat sacrocaudal spinal cord were labeled by intracellular injection of horseradish peroxidase, following physiological characterization. of these 36 neurons, 24 had cell bodies within lamina v. twelve lamina v neurons were multireceptive; i.e., they responded differentially to innocuous and noxious mechanical stimuli. most multireceptive neurons had the following morphological features: (1) large cell bodies; (2) extensive dendritic spreads in all direc ... | 1985 | 4044924 |
| prevalence of pig herds affected by pleuropneumonia associated with haemophilus pleuropneumoniae in eastern england. | a survey for the macroscopic lesions indicative of pneumonic infection in the pig with haemophilus pleuropneumoniae was made in an abattoir in eastern england. a total of 78 herds located in 11 counties of eastern or central england were seen between december 1982 and august 1983. lesions were noted in the batches submitted by 44 (56 per cent) of the 78 herds. a further 16 herds (21 per cent) submitted batches containing pigs affected by pleurisy principally of the caudal lobes but without the p ... | 1985 | 4049707 |
| haemophilus pleuropneumoniae (actinobacillus pleuropneumoniae). serotypes 8, 3 and 6. serological response and cross immunity in pigs. | immunity obtained by vaccination with haemophilus pleuropneumoniae is type specific and protection will only be obtained against the serotype contained in the vaccine. serotype 8 is closely related to serotypes 3 and 6 and the objective of the present study was therefore to examine if cross immunity between the three serotypes could be obtained at vaccination. | 1985 | 4059042 |
| characterization of haemophilus spp. isolated from healthy swine and evaluation of cross-reactivity of complement-fixing antibodies to haemophilus pleuropneumoniae and haemophilus taxon "minor group". | of 30 sows from a herd believed to be free of haemophilus pleuropneumoniae infection, 2 had complement-fixing antibodies to h. pleuropneumoniae serotype 5. necropsy and microbiological examination of the two sows revealed no evidence of h. pleuropneumoniae infection; however, haemophilus taxon "minor group" and a urease-negative, indole-positive haemophilus sp. were isolated from numerous respiratory tract sites in both sows. isolation of these haemophilus spp. was facilitated by serially diluti ... | 1985 | 4066924 |
| quantitative morphology of peracute pulmonary lesions in swine induced by haemophilus pleuropneumoniae. | twenty-seven six-week-old cesarean-derived, colostrum-deprived pigs were inoculated intratracheally with an isolate of haemophilus pleuropneumoniae serotype 5 (principles) of high virulence (i-200) or low virulence (b-8) or phosphate buffered saline (controls). pigs given i-200 had severe serofibrinous pleuropneumonia at three hours after inoculation; two of three pigs were dead by 24 hours after inoculation. interalveolar septa in the caudal lung lobes were 41% thicker than septa from control p ... | 1985 | 4082386 |
| effect of diphenylhydantoin on the metabolism of dicoumarol in man. | | 1971 | 4107730 |
| drug-induced changes in the release of 3 h-monoamines from field stimulated rat brain slices. | | 1971 | 4112831 |
| the effect of ethionine on the energy producing metabolism in the rat pancreas. 1. the influence on the activities of key enzymes of various metabolic pathways. | | 1973 | 4148877 |
| antigenic relationship of varicella-zoster and herpes simplex. | | 1965 | 4157772 |
| [histamine liberation by short chain aldehydes]. | | 1968 | 4172834 |
| passive transfer, with plasma, of delayed allergy in guineapigs. | | 1969 | 4179840 |
| the isolation of nuclei from the yeast schizosaccharomyces pombe. | | 1969 | 4187862 |
| [studies on the pregnancy-specific beta 1-glycoprotein (sp1) (author's transl)]. | | 1974 | 4211659 |
| the aromatization of 10-methyl and 10-hydroxymethyl steroids by human placental microsomes. | | 1965 | 4221182 |
| [species specific difference in binding to plasma proteins]. | | 1967 | 4231849 |
| the hematology of the germfree cat. | | 1969 | 4237320 |
| the effect of low doses of bis-(tri-n-butyl-tin)-oxide on the skin of rats. | | 1968 | 4239341 |
| isolation of plasma membrane fragments from hela cells. | a method for isolating plasma membrane fragments from hela cells is described. the procedure starts with the preparation of cell membrane "ghosts," obtained by gentle rupture of hypotonically swollen cells, evacuation of most of the cell contents by repeated washing, and isolation of the ghosts on a discontinuous sucrose density gradient. the ghosts are then treated by minimal sonication (5 sec) at ph 8.6, which causes the ghost membranes to pinch off into small vesicles but leaves any remaining ... | 1969 | 4239370 |
| contractility of the hypertrophied canine heart in chronic volume overload. | | 1969 | 4243335 |
| [congenital amegakariocytic thrombocytopenia with final pancytopenia, trisomy 21, and cystic fibrosis]. | | 1969 | 4245831 |
| a stable l-form of haemophilus pleuropneumoniae. | a stable l-form of haemophilus pleuropneumoniae (shope) was isolated from primary pig kidney cell tissue cultures which had been inoculated 28 days previously with glycine induced spheroplasts of this organism.h. pleuropneumoniae was definitely cytopathic in primary pig kidney cell cultures, producing cell rounding, cytoplasmic vacuolation and nuclear enlargement with peripheral condensation of nuclear dna. by contrast, the effect of spheroplasts was much less distinct, producing only loss of cy ... | 1970 | 4246004 |
| [study of certain biochemical indices in the tissues of the uterine horn and cervix]. | | 1972 | 4272597 |
| [study of certain biochemical indices in the tissues of the uterine horn and cervix]. | | 1972 | 4272597 |
| time relationships between injection of antigen and adjuvant. v. primary and secondary immune responses to sheep erythrocytes in mice pretreated with incomplete freund's adjuvant. | | 1973 | 4283266 |
| release of repressor control of ribonucleotide reductase by thymine starvation. | | 1965 | 4284298 |
| contraction of vascular smooth muscle in response to plasma. comparison with response to known vasoactive agents. | | 1966 | 4288688 |
| contraction of vascular smooth muscle in response to plasma. comparison with response to known vasoactive agents. | | 1966 | 4288688 |
| further evidence for angiotensin-sodium interaction in central control of fluid balance. | | 1970 | 4320106 |
| [stabilization of n-antigens of enteroviruses]. | | 1970 | 4322838 |
| renal damage in murine infection with reovirus 3: an ultrastructural study. | | 1969 | 4330554 |
| preliminary observations on egg transmission of turkey herpesvirus (hvt) in turkeys. | | 1972 | 4337315 |
| two physically and functionally distinct forms of eukaryotic 40s ribosomal subunits. | | 1973 | 4350951 |
| separation and comparison of primary structures of three formylmethionine trnas from e. coli k-12 mo. | | 1973 | 4358398 |
| cell death in the normal neonatal rat adrenal cortex. | | 1973 | 4359795 |
| mechanism of adrenaline-induced lipolysis in adipose tissue. | | 1974 | 4363679 |
| prostaglandins and the regulation of uterine blood flow in pregnancy. | | 1974 | 4364355 |
| [pathogenesis of cincophen ulcer of the stomach in dogs]. | | 1966 | 4393459 |
| investigations into yellow fever virus and other arboviruses in the northern regions of kenya. | previous studies having shown an appreciable level of yellow fever immunity to exist in northern kenya, further epidemiological and serological surveys were carried out there in 1968 in an attempt to define more clearly the distribution of yellow fever and to locate possible vector and reservoir hosts of the disease; these surveys also provided information on a number of other arboviruses.altogether 436 sera from 5 areas in northern kenya were screened by haemagglutination-inhibition tests with ... | 1970 | 4393661 |
| the n-terminal and c-terminal amino acid sequence of calf rennin. | | 1970 | 4399042 |
| [ultrastructural and biochemical modifications in the rat's submaxillary salivary gland mitochondria due to administration of some toxic agents and industrial powders]. | | 1974 | 4423631 |
| dissociation of gastric acid and serum gastrin responses to intraluminal calcium in man: influence of calcitonin and parathyroid hormone. | | 1974 | 4430422 |
| [characteristics of changes of carbohydrate, lipid and protein content of blood during vibration and the role of hypothalamus]. | | 1974 | 4432689 |