| interaction between penicillin and the dd-carboxypeptidase of the unstable l-form of proteus mirabilis strain 19. | binding of penicillin to the dd-carboxypeptidase of the unstable spheroplast l-form of proteus mirabilis results in the rapid formation of a modified enzyme-inhibitor complex which in turn undergoes rapid decay into reactivated enzyme and an antibiotically inactive penicillin degradation product. major antibiotic metabolites recovered from such interactions were benzylpenicilloic acid and phenoxymethylpenicilloic acid from benzylpenicillin and phenoxymethylpenicillin, respectively, suggesting a ... | 1978 | 348468 |
| cerulenin-induced changes in the lipopolysaccharide content and phospholipid composition of proteus mirabilis. | inhibition of proteus mirabilis growth by cerulenin, a specific inhibitor of fatty acid biosynthesis, was reversed by exogenously supplied fatty acid mixtures containing oleic acid and palmitic or pentadecanoic acids. the growth rate of the cells treated with cerulenin in the presence of the fatty acid mixtures was slower, however, than that of untreated cells, and their lipopolysaccharide content was decreased by 30-50%, resulting in an increased sensitivity of the organisms to rifamycin and va ... | 1978 | 348472 |
| chloramphenicol for oral treatment of canine urinary tract infections. | chloramphenicol was administered orally for 7 to 14 days to 83 dogs with urinary tract infections. the daily dosage of 99 mg/kg (45 mg/lb) was divided into 3 equal parts and administered at 8-hour intervals. response to treatment (negative urine culture after treatment) varied from 84% (11 to 13) for infections caused by staphylococcus aureus to 51% (24 of 47) for those caused by escherichia coli; 82% (14 of 17) of the infections caused by streptococcus spp and 63% (7 of 11) of those caused by p ... | 1978 | 348660 |
| an in vitro model of the urinary bladder. | | 1978 | 348666 |
| the effect of antibiotics and acetohydroxamic acid on bacterial hydrolysis of urea. | | 1978 | 348668 |
| antibacterial activity of cefamandole in vitro. | cefamandole, a new cephalosporin derivative, was found to have a broad spectrum of antimicrobial activity against a cross-section of both gram-positive and gram-negative bacteria isolated clinically. gram-positive cocci, except for streptococcus faecalis, were extremely susceptible to cefamandole; penicillin g-resistant staphylococcus aureus also was highly susceptible. minimal bactericidal concentrations for gram-positive cocci approximated the minimal inhibitory concentrations. strains of haem ... | 1978 | 349095 |
| management and microbiology of cutaneous abscesses. | cutaneous abscesses in the perineal region contain primarily anaerobes commonly found in stool. non-perineal abscesses contain mixed microflora indigenous to the skin. bacteroides fragilis, the only anaerobe resistant to penicillin, is found predominantly in the perineal area. staphylococcus aureus, although the most common aerobe found, is seen less frequently than expected and is almost always resistant to penicillin. escherichia coli and neisseria gonorrhoeae are rarely found. incision and dr ... | 1978 | 349218 |
| [sensitivity of clinical proteus strains to antibiotics and their combinations]. | in 1976 isolation of proteus from wounds of patients with various purulent processes amounted to 14.5 per cent. serotypes 0-10, 0-3 and h-3 predominated among the isolates. sensitivity of 35 clinical strains of proteus to 10 antibiotics, furagin and nevigramone was studied by the method of serial dilutions in liquid media. all the isolates were highly resistant to the antibiotics except gentamicin, furagin and nevigramone, the mic of which for most of the strains was 3.12, 1.6-3.12 and 6.25-12.5 ... | 1978 | 350143 |
| structure, function, and regulation of escherichia coli rrna in proteus mirabilis. | escherichia coli rrna genes have been introduced into proteus mirabilis on an f-prime factor (f'14). a portion of the ribosomes in the resulting merodiploid consist of e. coli rrna and p. mirabilis ribosomal proteins. these ribosomes are structurally similar to normal p. mirabilis or e. coli ribosomes and exhibit many or all of the functional properties of normal ribosomes. the accumulation of e. coli rrna in the merodiploid is regulated in a way similar to the the regulation of p. mirabilis rr ... | 1978 | 350828 |
| lipoprotein from proteus mirabilis. | the biosynthesis of a proteus mirabilis outer membrane protein of molecular weight of approximately 7,000 was found to be relatively resistant to puromycin and rifampin, as is the case for the escherichia coli liporotein. furthermore, the existence of the lipoprotein in p. mirabilis was indicated by a comparison of the amino acid compositions of the purified free and bound forms of this protein with those of the e. coli free and bound lipoproteins. | 1978 | 350832 |
| emergence of antibiotic-resistant bacteria in the intestinal flora of farm inhabitants. | | 1978 | 351088 |
| trimethoprim therapy for urinary tract infection. long-term prophylaxis in a uremic patient. | | 1978 | 351217 |
| anti-m in children with acute bacterial infections. | four children, 7 to 24 months old, were found to have anti-m at the time of admission to the hospital for severe acute bacterial infections. all were m-n+. two patients had meningitis, one had septic arthritis, and the fourth had a third-degree burn of the left hand. in follow-up studies the anti-m of patients no3 and no4 were no longer detectable after 12 and 11 months respectively. in all patients no demonstrable antibody was in either maternal or cord sera at time of birth. the clinical data ... | 1978 | 351884 |
| genetic and physiological characterization of escherichia coli k12 mutants (tabc) which induce the abortive infection of bacteriophage t4. | | 1978 | 351929 |
| [microfloral makeup of the feces of infants on various types of feeding]. | dissimilarity in the fecal microflora of infants fed with breast milk and the ones receiving in the neonatal period the mixture "malyutka" and experimental samples of the dry acidopilic mixture "malyutka" because of their mothers' state of hypolactation. features specific for intestinal biocenosis in the breast-nursed infants is the prevalence of bifidobacteria, low abundance of microorganisms accomplishing proteolysis and also a high percentage of colicinogenic cultures of colibacillus. in furt ... | 1978 | 351957 |
| influence of a gaba transaminase inhibitor on central nervous system oxygen toxicity. | a decrease in brain gaba concentration has been implied as the cause of convulsions induced by hyperbaric oxygen (hop). we therefore examined the influence of sodium valproate, an anticonvulsant and gaba transaminase inhibitor on hop-induced convulsions in rats. the mean latency of occurrence of the first electrical discharge in the ecog and the appearance of the first clinical seizure in awake chronically implanted rats was unchanged by administration of sodium valproate prior to hop exposure. ... | 1978 | 352331 |
| removal of non-specific antibodies from tetanus antitoxin serum by affinity chromatography using the antigens of a nontoxigenic derivative of clostridium tetani. | | 1977 | 352339 |
| inhibition of pyruvate dehydrogenase multienzyme complex from escherichia coli with mono- and bifunctional arsenoxides. | | 1978 | 352396 |
| interaction of lipopolysaccharide with detergents and its possible role in the detergent resistance of the outer membrane of gram-negative bacteria. | in the presence of mgcl2, amounts of detergents which disrupted phospholipid vesicles caused lipopolysaccharide i from proteus mirabilis to aggregate and form vesicular, membrane-like structures. vesicle formation with p. mirabilis lipopolysaccharide ii containing longer o-polysaccharide chains was extremely poor. lipopolysaccharides of salmonella minnesota r mutants (chemotypes ra, rc and re) displayed a growing tendency for vesicle formation with increasing deficiency of the r core polysacchar ... | 1978 | 352397 |
| [role of normal microflora in the treatment of vibrio carrier state in rat gnotobionts]. | materials on the study of interactions between vibrio cholera el tor and some indigenous bacteria of human intestinal tract, which proved to be active antagonists in vitro, are presented in this work. experiments were conducted on gnotobiotic rats (fisher), using various combinations and variants of the order of the microorganism administration; there were revealed no antagonistic relations between virbrio cholerae el tor and escherichia coli m-17, lactobacillus fermenti, lactobacillus plantarum ... | 1978 | 352437 |
| casein and alpha-lactalbumin detection in breast cancer cells by immunocytochemistry. | casein and alpha-lactalbumin are characteristic proteins produced by normal mammary cells under hormonal stimulation. specific antisera were used to immunochemically stain for these two proteins in the unstimulated r3230ac transplantable rat mammary tumor as well as in normal lactating rat mammary tissue. specific staining was observed in the lactating rat alveolar epithelial cells and in the cells lining the intraalveolar ducts with both antisera. in the r3230ac tumor some cells were shown to c ... | 1978 | 352508 |
| proteus mirabilis brain abscess in a neonate. | occasionally a brain abscess has been observed in a neonate. this report presents a unique case of a septic infant who developed a proteus mirabilis brain abscess shortly after birth, which persisted undetected until 21/2 months of age. | 1978 | 352771 |
| preparation of acid-fast microscopy smears for proficiency testing and quality control. | a method is presented for preparing smears for proficiency testing and quality control in acid-fast microscopy. the work was prompted by the increased demand for acid-fast bacilli positive smears with characteristic microscopic appearance and among-smear uniformity. | 1978 | 353070 |
| coding of stable 4s rna molecules by the resistance factor r1. | with the aid of dna-rna hybridization experiments it was shown that an e. coli strain harbouring the resistance factor r1 contains small, stable rna species which are capable of annealing with the dna of this r-factor. at a higher hybridization temperature rna molecules form the isogenic, sensitive strain could also hybridize to the r1-dna. these rna-species were again detected if the rna was extracted from p. mirabilis carrying this plasmid. the fact that sulfur-labelled rna also hybridized to ... | 1978 | 353512 |
| xanthogranulomatous pyelonephritis masquerading as occult malignancy. | xanthogranulomatous pyelonephritis (xgp) can present with weight loss, anemia, leukemoid reaction, and generalized debility; there may be no signs or symptoms referable to the urinary tract. confusion between xgp and renal adenocarcinoma is well recognized, but other malignancies can also be simulated. case histories of patients with proved xgp whose clinical presentations suggested occult malignancies are recorded. proteus urinary tract infection, calculi, and a nonvisualizing kidney on intrave ... | 1978 | 354158 |
| [bacterial plasmids]. | | 1978 | 354238 |
| amplification of the cytotoxin action of glucocorticoid in cultured l5178y lymphoblasts. | | 1978 | 354783 |
| serotyping in epidemiological tracing of nosocomially acquired proteus mirabilis in a geriatric ward. | samples taken from patients, staff, and hospital milieu at intervals of two weeks for 41 weeks were analysed for nosocomial spread of proteus mirabilis. eighty-eight per cent of 3,519 colonies were serotyped into 21 0 groups. by o grouping and h typing, nosocomial spread of p. mirabilis could be demonstrated in several cases between patients in the same room. no spread between rooms was found. the acquisition of p. mirabilis between patients probably occurred as the result of cross-infection due ... | 1978 | 355144 |
| differentiation of serratia marcescens and serratia liquefaciens by tests for lipase and phospholipase production. | the production of lipase and phospolipase by certain members of the enterobacteriaceae was examined by thin-layer chromatography of resting-cell suspensions incubated with triolein or lecithin. most strains of serratia marcescens produced both enzymes while most strains of serratia liquefaciens exhibited strong lipase but only a minor phospholipase activity. enterobacter spp. (25 strains), klebsiella pneumoniae (20 strains), escherichia coli (15 strains), citrobacter freundii (7 strains) and pro ... | 1978 | 355631 |
| studies of introital colonization in women with recurrent urinary infections. x. adhesive properties of escherichia coli and proteus mirabilis: lack of correlation with urinary pathogenicity. | the ability of a bacterial strain to adhere to the vaginal mucosa and the mucosa of the urinary conduits seems to be important in the pathogenesis of urinary infection. bacterial adherence to vaginal epithelial cells was measured in vitro for 37 strains of escherichia coli and 18 strains of proteus mirabilis isolated from the anus, bladder and renal pelvis. no correlation could be demonstrated between the adhesive properties of a bacterial strain and its clinical pathogenicity, suggesting that h ... | 1978 | 355660 |
| experimental gram-negative bacterial sepsis: reevaluation of the ability of rough mutant antisera to protect mice. | | 1978 | 356058 |
| [acute gastrointestinal tract disorders caused by proteus]. | | 1978 | 356422 |
| alternate pathway activation of complement in a proteus mirabilis ulceration of the cornea. | a 63-year-old patient had an extensive infiltration, ulceration, and eventual perforation of the cornea caused by proteus mirabilis. histopathological examination of corneal tissue that was obtained at keratoplasty disclosed that the stroma was ulcerated with a diffuse infiltration of polymorphonuclear leukocytes. immunopathological examination of the cornea revealed prominent and diffuse staining for properdin and c3 complement. there was an absence of staining for igg, iga, igm, ige, and c4 co ... | 1978 | 356830 |
| control of acetohydroxy acid synthetase in escherichia coli 9723. | a method by which three acetohydroxy acid synthetase activities are separated from extracts of escherichia coli 9723 has been developed. isoleucine specifically represses synthesis of one of the enzymes, which is not sensitive to valine inhibition, and isoleucine also simultaneously enhances the production of a second activity, which is valine inhibitable. the valine-inhibitable activity is repressed by leucine and valine, a combination of which is more effective than either alone. the third ace ... | 1978 | 356876 |
| aminoacyl-trna synthetases from yeast: generality of chemical proofreading in the prevention of misaminoacylation of trna. | the specificity of valyl-, phenylalanyl-, and tyrosyl-trna synthetases from yeast has been examined by a series of stringent tests designed to eliminate the possibility of artefactual interference. valyl-trna synthetase, as well as activating a number of amino acid analogues, will accept alanine, cysteine, isoleucine, and serine in addition to threonine as substrates for both atp-ppi exchange and transfer to some trnaval species. the transfer is not observed if atempts are made to isolate the ap ... | 1978 | 356880 |
| relationship between the effect of carbenicillin on the phagocytosis and killing of proteus mirabilis by polymorphonuclear leukocytes and therapeutic efficacy. | | 1978 | 357365 |
| ultrastructure of an unstable l-form strain p42l of proteus mirabilis. | | 1978 | 357673 |
| mobilization of the proteus mirabilis chromosome by r plasmid r772. | the p-1 incompatibility group plasmid r772 can mobilize the chromosome of proteus mirabilis strain pm5006. the decreasing gradient of recombinant recovery frequencies found for markers which were increasingly distal to 0 min with plasmid d donors was not found with r772. instead, it produced recombinants for all markers at frequencies of about 5 x 10(-5) per donor. this is about 10-fold lower than the plasmid transfer frequency. recombinants were stable and recombination was only detected over s ... | 1978 | 357678 |
| occult chronic septic arthritis due to proteus mirabilis. | | 1978 | 357766 |
| urinary tract infections in girls: age at onset and urinary tract abnormalities. | | 1978 | 358124 |
| urinary tract infections caused by proteus mirabilis in children. the antibody response to o and h antigens and tamm-horsfall protein and bacterial adherence to uro-epithelium. | sera from seven girls with acute symptomatic pyelonephritis and nine children with acute symptomatic cystitis caused by proteus mirabilis were analysed for antibodies against the bacterial o and h1 antigens and the tamm-horsfall protein. an increase in antibody levels against o antigen and tamm-horsfall protein was noted only in patients with acute pyelonephritis indicating that antibody determinations can be useful in differentiating between upper and lower urinary tract infection caused by pro ... | 1978 | 358736 |
| analysis of amines and other bacterial products by head-space gas chromatography. | a gas chromatographic (gc) head-space technique is presented, which is suitable for the analysis of volatile products in bacterial broth cultures. this is exemplified by studies on clostridium septicum, klebsiella pneumoniae and proteus mirabilis. the media were acidified or made alkaline and after heating, samples of the gas phase above the media were directly injected into the gas chromatograph. a gas chromatograph equipped with dual columns and flame ionization detectors was used, employing p ... | 1978 | 358746 |
| [antibiotic sensitivity of the h- and o-forms of bacteria in the genus proteus]. | proteus strains isolated from the gastro-intestinal tract of children not older than 1 year were characterized by resistance to oxytetracycline, chlortetracycline, benzylpenicillin and erythromycin. the strains were more sensitive to neomycin, monomycin and streptomycin. antibiotic sensitivity of pr. mirabilis and pr. vulgaris strains increased on transfer from h- to o-form. inverse dependence of the urease activity of the strains on their sensitivity to tetracyclines was noted. | 1978 | 358911 |
| [chemotherapy of experimental lactational mastitis in mice]. | more severe mastitis on infection with proteus was shown on a standardized model of experimental lactation mastitis of mice caused by staphylococcus, proteus and their mixture. significant differences in the morphological pictures of the staphylococcal and proteus mastitis were noted. a pronounced effect was observed with the use of kanamycin in combination with fuzidin in treatment of experimental mastitis of various etiology. | 1978 | 358913 |
| influence of pili on the virulence of proteus mirabilis in experimental hematogenous pyelonephritis. | the ability of heavily and lightly piliated proteus mirabilis to infect the renal parenchyma was compared in a model of hematogenous pyelonephritis. cortical abscesses occurred in 13 of 24 rats injected with lightly piliated p. mirabilis but in none of 24 rats challenged with heavily piliated organisms (p less than 0.001). lightly and heavily piliated organisms were cleared from the vasculature equally rapidly and were also delivered to the kidney in equal numbers. during the first 24 hr, howeve ... | 1978 | 361900 |
| initial urinary tract infection caused by proteus mirabilis in infancy and childhood. | | 1978 | 361938 |
| an overview of results of world-wide clinical trials with cefadroxil. | céfadroxil, a new semisynthetic oral cephalosporin, is absorbed similarly by fasted and non-fasted subjects, produces sustained serum levels and is eliminated at a relatively slow rate. these pharmacokinetic properties permit less frequent and more convenient dosage scheduling than cephalexin and cephradine and consequently greater patient compliance. cefadroxil was evaluated for safety in 1051 patients and for efficacy in 1030 patients. overall it achieved a 91.8% rate of clinical success resul ... | 1978 | 363481 |
| [antibiotic policy and bacterial resistance]. | | 1978 | 364322 |
| [lysogeny in bacteria of the genus proteus and use of moderate phages for direct typing]. | | 1978 | 364892 |
| identification of proteus morganii and distinction from other proteus species. | the identification of proteus morganii in the clinical laboratory is complicated by the differences in incidence of hydrogen sulfide (h2s) production recorded by different sources. since this quality appeared to be a frequent feature of strains of p. morganii at the author's center, all isolates of this species were studied over a six-month period. during this time, 12 of 21 were found to produce scant h2s in kligler's iron agar (kia) and triple-sugar iron (tsi) agar butts. the strains were, in ... | 1978 | 364977 |
| effect of triton x100 on the oxidation of l-phenylalanine by membranes of proteus mirabilis. | | 1978 | 365248 |
| recurrences in primarily infected and uninfected urolithiasis. | an analysis was carried out of 640 patients treated because of urolithiasis at the urological clinic of the medical academy in warsaw in the years 1971--1974. factors conducive to stone formation were analyzed. in infected urolithiasis, different bacterial floras were found in men and women. the importance of infections acquired in hospital by patients is emphasized. in primarily uninfected urolithiasis there were 35 per cent recurrences, as against 53 per cent recurrences in infected urolithias ... | 1978 | 365823 |
| extension of a chromosome linkage group of proteus mirabilis. | mating procedures for detection of mobilization of the proteus mirabilis chromosome were re-investigated. the chromosome was mobilized by plasmid d, the previously used hybrid between plasmids p-lac and r1drd19. about a 40-fold increase in recombinant recovery correlated with the absence of swarming during mating and a lower temperature of incubation. the modification introduced was that conjugation was allowed to proceed on a non-selective supplemented minimal medium at 30 degrees c before wash ... | 1978 | 366071 |
| urinary tract infection in general practice. | in three studies, 616 patients (610 female and six male) presented with symptoms suggesting urinary tract infection (uti). of these, 321 had greater than 100 x 10(6) bacteria per litre in a midstream urine sample. none of the presenting symptoms could be considered to be a reliable indicator of bacteriuria. ninety percent of infected urines and 44 percent of uninfected urines had a raised white cell concentration. escherichia coli was the most common infecting organism (71.3 percent). next were ... | 1978 | 366474 |
| macrophage secretion and the complement cleavage product c3a in the pathogenesis of infections by mycoplasmas and l-forms of bacteria and in immunity to these organisms. | mouse peritoneal macrophages in culture exposed to mycoplasma pulmonis show marked biochemical changes. this micro-organism induces the release of hydrolytic enzymes from macrophages. the release is time- and dose-dependent and is not associated with loss of the cytoplasmic enzyme lactate dehydrogenase or any other sign of cell death. secretory products of macrophages may play a role in the pathogenesis of chronic inflammatory responses elicited by mycoplasma infections. one of the products of a ... | 1978 | 367651 |
| regulation of phenylalanine oxidase synthesis in proteus mirabilis. | cells of proteus mirabilis could oxidize l-phenylalanine to phenylpyruvate only when grown in the presence of a number of amino acids, particularly, l-alanine, l-asparagine, l-glutamate, and l-glutamine. production of phenylalanine oxidase was slowly lost upon growth in a minimal medium containing ammonium ions as a nitrogen source but was reversed by the addition of casein hydrolysate. oxidase activity as well as a phenylalanine-dichlorophenolindophenol (dcip) reductase activity increased in p. ... | 1979 | 368013 |
| penicillin-binding proteins in proteus species. | penicillin-binding proteins in three species of proteus, proteus mirabilis, p. morganii, and p. rettgeri, were investigated by sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis. penicillin-binding proteins in these proteus species were compared with those in escherichia coli k-12. an approximate correlation between penicillin-binding proteins in e. coli and those in proteus species was shown by several criteria: electrophoretic mobilities; affinities of several beta-lactam antibioti ... | 1979 | 368025 |
| conduiturinary diversion and urinary-tract infection. i. serum antibody titers against escherichia coli and proteus mirabilis in relation to urographic findings. | the serum antibody titers against escherichia coli and/or proteus mirabilis were elevated in 26 of 80 patients (33%) with a conduit urinary diversion. urographic findings were abnormal in 44 of these 80 patients (55%). urography was normal in 59% of the patients with normal antibody titers, but in only 15% of those with elevated titers. raised antibody levels against e. coli o antigen (greater than 256 before and/or greater than 32 after mercaptoethanol treatment of serum) were associated with w ... | 1979 | 368976 |
| conduit urinary diversion and urinary-tract infection. ii. raised serum antibody titers against escherichia coli and proteus mirabilis in relation to bacteriologic findings. | elevated serum antibody titers against escherichia coli and/or proteus mirabilis were found in 35% of 89 patients with a conduit urinary diversion. statistical analysis showed significant correlation between the titers and growth of e. coli or p. mirabilis in conduit urine. but 17 (24%) of 72 patients without e. coli in urine cultures had raised e. coli antibody titer. only 3 (4%) of 68 patients without growth of p. mirabilis had raised p. mirabilis antibody titer. when the post-diversion observ ... | 1979 | 368977 |
| the recovery period following exposure of bacteria to penicillins. | experiments with staphylococcus aureus and streptococcus pyogenes have shown that when cells are exposed to bactericidal concentration of benzylpenicillin or ampicillin and the antibiotic then inactivated with beta-lactamase the count of the surviving viable cells (colony-forming units) remains essentially constant for a period of approximately 1.5--3 h before increasing at a normal rate. no such recovery period was observed, however, when escherichia coli or proteus mirabilis was exposed to a b ... | 1979 | 369783 |
| simultaneous nosocomial outbreaks caused by multiply resistant klebsiella pneumoniae types 2 and 30. | two simultaneous klebsiella pneumoniae outbreaks resistant to multiple antibiotics are reported. the closely related strains were distinguished by comparing the zone diameters obtained by disk diffusion susceptibility testing but not by interpretations of susceptible, resistant, or intermediate. similar conclusions were made when minimal inhibitory concentrations were considered. the separation was subsequently confirmed by capsular serotyping into types 2 and 30. the data presented suggest that ... | 1978 | 370152 |
| [basic and clinical examinations of cs-1170 in pediatrics (author's transl)]. | 1. cs-1170 was administered for the purpose of prophylaxis during cardiac catheterization in patients with heart disease, and its blood levels were measured. 2. the mean blood level (moni-trol i standard) after one intravenous shot of 20 mg/kg was 53.6 mcg/ml in catheterized children aged below 6 and 66.9 mcg/ml in catheterized children aged above 10 at 30 minutes, and 1.95 mcg/ml and 5.2 mcg/ml respectively at 6 hours. 3. the mean half life of the blood level was 1.09 hours in catheterized chil ... | 1979 | 370423 |
| alteration of perirenal fat secondary to diffuse retroperitoneal infiltration. | inflammatory effusions and diffuse neoplasia in the fatty retroperitoneal space, which can alter the perirenal fat, can be recognized radiographically because of density differences. the opacity of fluid and tumor accentuates the remaining fat which conforms to the renal contour. this perirenal fatty border appears as a lucent strip when the perirenal fat is not violated and as abnormal perirenal streakiness when the perirenal fat is infiltrated by fluid or tumor. six cases are described. | 1979 | 370904 |
| [detection and study of the labile toxic factor of proteus mirabilis]. | the author studied the dynamics of toxin formation of the high- and low-virulent pr. mirabilis strains. the high-virulent strain produced toxic substances of the exotoxin type detectable in 1-2-day broth cultures. later the activity of the culture medium of both cultures under study was due to substances of the endotoxin type. by physico-chemical and immunobiological properties, and also by chemical composition of pr. mirabilis "early toxin" was similar to the exoenterotoxins of enterobacteria. ... | 1979 | 371267 |
| endotoxin in germfree, gnotobiotic, or conventional-flora sprague-dawley rats. | the limulus assay for bacterial endotoxin was performed on serum and (or) plasma from animals monoassociated with clostridium species, staphylococcus aureus, escherichia coli, proteus mirabilis, enterobacter agglomerans, bacteroides fragilis, klebsiella pneumoniae, or candida albicans. plasma from animals monoassociated with the gram-negative bacteria or c. albicans consistently showed a positive limulus test while conventional-flora controls, germfree rats, and gnotobiotic animals monoassociate ... | 1978 | 371771 |
| trimethoprim in combination with a sulfonamide for oral treatment of canine urinary tract infections. | trimethoprim, in combination with sulfadiazine or sulfamethoxazole was administered orally for 7 to 14 days to 84 dogs with urinary tract infections (uti). the daily dosage of 26.4 mg/kg (12 mg/lb) was divided into 2 equal parts and administered at about 12-hour intervals. response to treatment, based on negative urine culture during or after therapy, was 37 of 45 (82%) for uti caused by escherichia coli, 11 of 15 (73%) uti caused by proteus mirabilis, 8 of 12 (67%) uti caused by klebsiella pneu ... | 1979 | 372165 |
| genetic circularity of the proteus mirabilis linkage map. | the t incompatibility group plasmid r394 can mobilize the chromosome of proteus mirabilis strain pm5006. it transferred relatively large segments, corresponding to at least 20 min on the d plasmid chromosomal map of the organism. the frequency of recombination for a large number of selected markers was nearly constant at 5 x 10(-6) per donor cell and it is concluded that mobilization takes place from a number of chromosomal sites. all recombinants were r+ and displayed all properties of the plas ... | 1979 | 372488 |
| the special affinity of particular types of proteus mirabilis for the urinary tract. | the strains of proteus species found in significant numbers and as pure cultures in urine from 217 individuals were isolated, identified to species level and typed for proticine production (p type) and proticine sensitivity (s type) to give their p/s type. urinary-tract infections with proteus, principally p. mirabilis, were associated with the elderly. ninety seven distinct p/s types were found but three p/s types p3/s1,8, p3/s1,8,13 and p3/s1,13 were isolated at a much higher frequency (14%) t ... | 1979 | 372530 |
| dysuria in general practice. | an analysis of 98 clinical consultations for dysuria in an urban general practice revealed that only 60 percent of patients had proven urinary tract infections. two percent had gonorrhoea and the rest had an urethral syndrome. most of the urinary tract infections were caused by escherichia coli and streptococcus epidermidis. proteus mirabilis was the next commonest infecting organism. among the commonly used urinary antimicrobials, nitrofurantoin was found to be the cheapest and most effective a ... | 1979 | 372868 |
| immunochemical studies on free lipid a from proteus mirabilis 1959. | the chemical composition and serological activity of free lipid a from proteus were studied. only two fatty acids: myristic acid and 3-hydroxymyristic acid were detected. when calculated for glucosamine disaccharide unit, 2 moles of ester-linked and 1 mole of amide-linked fatty acid are present. amino group of glucosaminyl residue is substituted by 3-hydroxymyristic acid. the occurence of an uncommon (4-aminoarabinose) substituent, attached outside the backbone, was noticed. the results of serol ... | 1978 | 373679 |
| gene copy number effects in the mer operon of plasmid nr1. | the level of resistance to hg2+ determined by the inducible mer operon of plasmid nr1 was essentially the same for three gene copy number variants in escherichia coli, less in proteus mirabilis, and intermediate in p. mirabilis "transitioned" to a high r-determinant gene copy number. cell-free volatilization rates of radioactive mercury indicated increasing levels of intracellular mercuric reductase enzyme from low- to high-gene copy number forms in p. mirabilis and from low- to high-copy number ... | 1979 | 374374 |
| properties of r plasmid r772 and the corresponding pilus-specific phage pr772. | r plasmid r772 was isolated from a strain of proteus mirabilis and is a self-transmissible p-1 incompatibility group plasmid having a molecular weight of about 27 x 10(6). it renders bacterial hosts resistant to kanamycin. phage pr772 was isolated as a phage dependent on the presence of r772 in bacterial hosts. it is hexagonal-shaped with a diameter of 53 nm, has a thick inner membrane and no tail. vaguely defined appendages are sometimes apparent at some vertices and the phage possesses double- ... | 1979 | 374677 |
| [bactericidal activity of amoxicillin. in vitro bactericidal activity and therapeutic effect for experimental infections (author's transl)]. | | 1979 | 374774 |
| [urinous pleural effusion associated with obstructive nephropathy]. | | 1978 | 374932 |
| [f' transfer from escherichia coli to proteus mirabilis]. | the task of this work was the establishment of an effective transfer system for f'-plasmids from escherichia coli to proteus mirabilis. it is shown that cells of pg vi act as recipients in crosses with e. coli f' strains but with a low transfer rate of the plasmid. the presumption that a restriction -- modification system in p. mirabilis was the only reason for the low transfer could not be confirmed. an indirect selection method was developed to isolate p. mirabilis cells which are better recip ... | 1979 | 375599 |
| [probability of resistance to 10 standard- and 7 recently introduced antimicrobics in multiresistant strains of escherichia coli, proteus mirabilis and klebsiella spec (author's transl)]. | | 1979 | 375624 |
| [multiple drug resistance in different medical institutions: frequency and resistance patterns in escherichia coli, proteus mirabilis and klebsiella spec (author's transl)]. | | 1979 | 375625 |
| reproducibility of biotypes using enterotubes. | using both stock and clinical isolates, the enterotube system was examined for reproducibility of its biotype identification. fifty stock strains of enterobacteriaceae were tested on each of 22 separate days (interrun evaluation), and ten enterotubes per strain were inoculated from one subculture (intrarun evaluation). it was found that 2 of the 50 strains (4 percent) demonstrated reproducibility of biotypes, defined as no variation in the results of the 22 interrun enterotubes. twenty-one of th ... | 1979 | 375727 |
| [expression of the gene for tetracycline resistance of plasmids r6 and rp4 in bacteria of the family enterobacteriaceae]. | it was found that manifestation of the tetracycline resistance gene depended on the type of the plasmid containing the gene. the tetracycline resistance gene was subject to less repression in plasmid r6 than in plasmid rp4. sensitivity of the initial plasmid-free bacteria varied within lower dose ranges than that of the plasmid-carrying strains. regulation of the tetracycline resistance gene manifestation in the given plasmid may change in different bacterial hosts, i.e. in different cytoplasmic ... | 1979 | 375821 |
| [mechanisms of proteus resistance to chloramphenicol]. | data on chloramphenicol sensitivity of clinical proteus strains isolated within 1970--1975 and some mechanisms of their resistance to this antibiotic are presented. it was found that most of the proteus strains (62.82 +/- 2.15 per cent) were resistant to chloramphenicol. 75 per cent of the isolates had resistance of transmissive character. resistance of the proteus cultures to chloramphenicol was not a stable feature and was lost during storage under laboratory conditions. direct correlation bet ... | 1979 | 375826 |
| in vitro sensitivity of proteus organisms to gentamicin and sisomicin. | the antibacterial activity of gentamicin and sisomicin was studied in 148 recent clinical isolates of proteus obtained from patients hospitalized in athens. both gentamicin and sisomicin were found to be active with sisomicin generally being the more active of the two; p. mirabilis strains were less susceptible than the indole-positive strains, but p. mirabilis organisms isolated from the respiratory tract were more sensitive to sisomicin than those isolated from the urine. susceptibility testin ... | 1979 | 376234 |
| prevention of colonization of the urinary tract of mice with escherichia coli by blocking of bacterial adherence with methyl alpha-d-mannopyranoside. | methyl alpha-d-mannopyranoside (alpha mm), a competitor inhibitor of the binding of mannose by escherichia coli, was tested for its ability to prevent infection of the urinary tract of mice with infective strains of the organisms. injection of the bacteria in the presence of the drug resulted in a considerable reduction in the number of bacteriuric mice. in this system alpha mm was inactive against proteus mirabilis in accordance with its inability to inhibit the adherence of this organism to ep ... | 1979 | 376757 |
| a nosocomial outbreak of infections due to multiply resistant proteus mirabilis: role of intestinal colonization as a major reservoir. | an outbreak of nosocomial infections involving an unusual strain of multiply resistant proteus mirabilis (phage type 8888) occurred in 15 patients, 14 of whom were in the surgical intensive care unit at that time. no common source of infection was identified, and person-to-person transmission was the most likely mode of spread. case-control analysis indicated a significantly increased risk infection related to length of hospital stay (p less than 0.005), number of operations (p less than 0.005), ... | 1979 | 376760 |
| urinary tract infection re circumcision. | | 1979 | 376804 |
| factors which influence the electron microscopic appearance of dna when benzyldimethylalkyammonium chloride is used. | | 1979 | 376868 |
| indomethacin and occult infections. | | 1979 | 376879 |
| what if multiple sclerosis isn't an immunological or a viral disease? the case for a circulating toxin. | the literature contains studies on many causes of demyelination: vascular occlusion--exogenous toxins--allergic reactions--and virus diseases. there remains, however, a small group of conditions which seems to have been ignored almost completely in discussions of cerebral demyelination. these consist of brain damage apparently resulting from some toxin liberated within the human body and not obtained from the outside. | 1979 | 377118 |
| a comparison of the antibacterial activity of sulphonamide-trimethoprim combinations. | sensitivity patterns of 326 clinical isolates toward sulphonamide/trimethoprim combinations were tested in vitro. the relative merits of the different combinations are discussed in their pharmacological and bacteriological contexts. it is concluded that organisms sensitive to cotrimoxazole as judged by in vitro sensitivity tests performed at 37 degrees c are also sensitive to sulphamoxole/trimethoprim. | 1979 | 377523 |
| composition, subclass distribution, and preliminary analysis of the functions of host inflammatory cells infiltrating renal allografts during rejection. | | 1979 | 377712 |
| determination of lipopolysaccharide by a bioluminescence technique. | the determination of the lipid a content of bacterial lipopolysaccharide by using a dim mutant of the luminous bacterium beneckea harveyi is described. the luminous bacteria emitted light upon the addition of an acid hydrolysate of lipopolysaccharide which contained myristic acid, thus making it possible to detect as little as 1 ng of lipopolysaccharide. by converting the 3-oh-myristic acid to myristic acid, it was possible to further increase the detection sensitivity and to establish a basis f ... | 1979 | 378133 |
| alterations in the cell envelope composition of proteus mirabilis during the development of swarmer cells. | long, swarming cells of proteus mirabilis had different proportions of some lipopolysaccharide components when compared to short cells, either agar grown or broth grown. fluorescence spectrophotometry of antibody binding, and sodium dodecyl sulphate-polyacrylamide gel electrophoresis indicated that the change was in the proportion of lipopolysaccharide with long o-antigenic sidechains, swarmer lipopolysaccharide relative to short sidechain lipopolysaccharide than the non-swarming cells. the prot ... | 1979 | 378265 |
| [regulation of catalase synthesis in proteus mirabilis]. | during the log-phase growth of proteus mirabilis the specific activity of catalase decreases, while at the beginning of or during the stationary phase an increase takes place which is abolished by inhibitors of nucleic acid or protein synthesis. glucose in the culture medium has no appreciable effect on the level of enzyme synthesis nor does the passage of bacteria to anaerobiosis bring any noticeable change. successive additions of hydrogen peroxide up to weak final concentrations (0.2--0.5 mm) ... | 1979 | 378338 |
| [properties of an hydrogen peroxide resistant proteus mirabilis mutant]. | a peroxide-resistant mutant (pr) was isolated from proteus mirabilis using the hydrogen peroxide mutagenic property. under the same conditions, resistance of mutant pr bacteria to h2o2 was 50 to 100 times greater than that of the wild type. the total amount of catalase produced by p. mirabilis pr was on the average 10 times greater than that of the wild type. when pr bacteria were subjected to high doses of h2o2 (150mm), the determination of catalasic activity in vivo increased; paradoxically, t ... | 1979 | 378339 |
| asymmetric transcription of r plasmid nr1 in proteus mirabilis. | the composite r plasmid nr1, its resistance transfer factor which specifies resistance to tetracycline (rtf-tc component), and its r-determinants component were each denatured and centrifuged to equilibrium in cscl density gradients containing polyuridylic acid-polyguanidylic acid. the complementary deoxyribonucleic acid strands of nr1 and the complementary strands of the rtf-tc component could be separated by this technique because of a threefold difference in polyuridylic acid-polyguanidylic a ... | 1979 | 378944 |
| synthesis and antibacterial activity of 2'-substituted chelocardin analogues. | chelocardin (1) was condensed with numerous hydrazines, hydrazides, and anilines, yielding 2'-substituted derivatives with antibacterial spectra similar to the parent antibiotic. the hydrazone derivatives 9 and 10 and the two anilino derivatives 42 and 44 had more in vivo antibacterial activity than chelocardin. | 1979 | 379332 |
| measurement of proteus cell motility during swarming. | the motilities of proteus long forms during swarming on agar were measured on cells transferred to liquid suspension. during concentric-ring formation on solid medium, when the edge of the swarm was advancing slowly or had stopped, the velocity of long-form motility was low. when the colony was spreading rapidly, long-form velocitywas relatively high. this periodic variation in cell velocity, which determines the zones formed during swarming, cannot adequately be explained by negative chemotaxis ... | 1979 | 379339 |
| infections of the temporomandibular joint. | three interesting case histories of infection of the temperomandibular joint are reported. an unsuccessful search of the recent literature was made in the hope that some assistance would be obtained in understanding the pathology. these infections must have been more common in the pre-antibiotic era and perhaps a search of the older literature would have been more fruitful. | 1979 | 379359 |
| [morphological studies on antibacterial activities of cefotiam (author's transl)]. | 1. cefotiam was demonstrated to be more potent than cefazolin in its antibacterial activities against clinical isolates of e. coli, klebsiella, serratia, proteus mirabilis, proteus morganii and proteus inconstans. mics of cefotiam with 10(6) cells/ml inoculum size were considerably lower than those with 10(8) cells/ml. 2. organisms lysed when exposed to cefotiam at concentrations higher than the mics with 10(8) cells/ml. morphological changes of organisms into filament occurred even at concentra ... | 1979 | 379387 |
| [proteeae enzymes that participate in the amino acid metabolism of food products]. | biosynthesis of enzymes, catalyzing amino acid conversion in food products, and deposition of end products of protein metabolism is a current problem for hygiene-indicatory microorganisms. results are reported of a study of decarboxylase and aminotransferase activities of a large number of proteus strains. it was found that aminotransferases are produced by all members of this group of microorganisms, despite the specific differences in their quantitative characteristics. the composition of the ... | 1979 | 379858 |
| disseminated nocardiosis in an immunosuppressed host. response to trimethoprim-sulfamethoxazole. | | 1979 | 379966 |