| mefloquine improved progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus. | we describe a case of a 67-year-old man with systemic lupus erythematosus who presented with progressive left hemiplegia. although the cerebral spinal fluid (csf) polymerase chain reaction (pcr) for the jc virus was negative, a brain biopsy confirmed the diagnosis of progressive multifocal leukoencephalopathy (pml). the tapering of prednisone and the use of cidofovir could not arrest the disease progression. administration of mefloquine stopped the extension of the lesion, and resulted in obviou ... | 2012 | 22687798 |
| [case of hiv-associated nephropathy accompanied by nephrotic syndrome and acute worsening of kidney function]. | a previously healthy black man presented with acute kidney injury wtih nephrotic syndrome. his serum creatinine and albumin concentrations were 8.0 mg/dl and 0.4 g/dl, respectively. renal ultrasound demonstrated an enlarged kidney with an extremely high echogenic cortex. human immunodeficiency virus (hiv) was serologically positive, and kidney biopsy revealed a collapsing variant of focal segmental glomerulosclerosis with interstitial nephritis. he was diagnosed as having hiv-associated nephropa ... | 2012 | 22590962 |
| remission of progressive multifocal leukoencephalopathy following highly active antiretroviral therapy in a man with aids. | a 43-year-old caucasian homosexual man with aids presented with blurring of vision, change of personality, and memory loss in march 1999. he had first been admitted 2 months previously for treatment of pneumocystis jiroveci pneumonia. a magnetic resonance imaging scan on admission showed multiple white matter lesions involving both subcortical cerebral hemispheres and cerebellar regions, with no mass effect or surrounding edema. jc virus was detected by nested polymerase chain reaction in the ce ... | 2012 | 22536089 |
| towards semi-automated curation: using text mining to recreate the hiv-1, human protein interaction database. | manual curation has long been used for extracting key information found within the primary literature for input into biological databases. the human immunodeficiency virus type 1 (hiv-1), human protein interaction database (hhpid), for example, contains 2589 manually extracted interactions, linked to 14,312 mentions in 3090 articles. the advancement of text-mining (tm) techniques has offered a possibility to rapidly retrieve such data from large volumes of text to a high degree of accuracy. here ... | 2012 | 22529179 |
| impaired maraviroc and raltegravir clearance in a human immunodeficiency virus-infected patient with end-stage liver disease and renal impairment: a management dilemma. | current product labels for maraviroc and raltegravir provide no dosing guidance for patients with end-stage liver disease and worsening renal function. we describe a 41-year-old man with human immunodeficiency virus (hiv) infection and rapidly progressive liver failure and vanishing bile duct syndrome at presentation. despite discontinuation of all potential offending drugs, the patient's liver function continued to deteriorate. to achieve and maintain hiv suppression while awaiting liver transp ... | 2012 | 22392831 |
| acceptable plasma concentrations of raltegravir and etravirine when administered by gastrostomy tube in a patient with advanced multidrug-resistant human immunodeficiency virus infection. | to determine whether the absorption of four antiretroviral agents-raltegravir, etravirine, emtricitabine, and tenofovir-is compromised when administered by gastrostomy tube. | 2012 | 22392423 |
| mirtazapine and mefloquine therapy for progressive multifocal leukoencephalopathy in a patient infected with human immunodeficiency virus. | a case of progressive multifocal leukoencephalopathy (pml) in a patient infected with human immunodeficiency virus (hiv) treated with mirtazapine and mefloquine is reported. | 2012 | 22382480 |
| disseminated kidney tuberculosis complicating autosomal dominant polycystic kidney disease: a case report. | mycobacterium tuberculosis infection in patients with autosomal dominant polycystic kidney disease (adpkd) is rare, and its diagnosis and treatment are difficult because numerous cysts are exposed to infection and antibiotics do not easily penetrate infected cysts. here, we report the case of a 43-year-old japanese man with disseminated urogenital tuberculosis (tb) and adpkd without human immunodeficiency virus (hiv) infection. delayed diagnosis and ineffective anti-tb chemotherapy worsened his ... | 2012 | 22377257 |
| hypercortisolism caused by ritonavir associated inhibition of cyp 3a4 under inhalative glucocorticoid therapy. 2 case reports and a review of the literature. | recent in vitro and in vivo studies have shown a potent inhibition of cytochrome p450 cyp3a4 through human immune deficiency virus (hiv) protease inhibitors (pis). the pi ritonavir is described as the most potent compound within these cyp3a4 inhibitors. we present 2 cases who developed the sequelae of glucocorticoid excess following ritonavir therapy and inhalative glucocorticoid treatment: a 60-year-old hiv positive man developed the typical symptoms of cushing's syndrome and a 52-year-old hiv ... | 2012 | 22328106 |
| simultaneous diagnosis of cryptogenic organizing pneumonia and hiv in a 45 year old man. | cryptogenic organizing pneumonia (cop) is a small airways disease characterized by intraluminal polyps of myxoid connective tissue which follows a subclinical course and is associated with infectious as well as non infectious processes the concomitant occurrence of human immunodeficiency virus (hiv) infection and cop has rarely been reported. we describe a unique case in which cop was a presenting feature in a patient with newly diagnosed hiv infection. | 2012 | 23569519 |
| bilateral arteritis with cytomegalovirus retinitis in a patient infected with human immunodeficiency virus. | to report an interesting ocular finding and course of bilateral arteritis with cytomegalovirus retinitis in a patient infected with the human immunodeficiency virus (hiv). | 2010 | 25390115 |
| salmonella typhimurium epidural empyema in an hiv-infected patient. | salmonella focal intracranial infections are reported rarely. they tend to occur in immunocompromised patients. we present here a case of salmonella typhimurium epidural empyema, with osteomyelitis of the adjacent frontal bone, in a 37-year-old human immunodeficiency virus positive man who presented with a three-day history of headache, fever, and sweats. he was treated successfully with antibiotics and surgical drainage. | 2009 | 24470883 |
| specific immunotherapy in a pollen-allergic patient with human immunodeficiency virus infection. | : according to the world health organization position paper, immunodeficiency such as human immunodeficiency virus (hiv) infection is a relative contraindication for specific immunotherapy (sit). since the introduction of highly active antiretroviral therapy, a significant reconstitution of immune competence in individuals with hiv is possible. | 2009 | 23282982 |
| diffuse cerebral vasculopathy in a hiv-positive patient with recurrent strokes. | the causes of ischemic stroke in the young adult are diverse. human immunodeficiency virus (hiv) infection-related vasculopathy is usually not included in the list of differential diagnoses. hiv-positive patients may present with acute neurologic dysfunction of different causes, among which cerebral infarction is an uncommon one. herein, we report a hiv-infected young man who suffered from recurrent ischemic strokes with evidence of cerebral vasculopathy on serial magnetic resonance images. | 2008 | 24256749 |
| bilateral sudden hearing loss in waldenstrom's macroglobulinemia: mr appearance. | a 46 year-old man with acquired immunodeficiency syndrome presented with sudden development of vertigo and tinnitus and then simultaneous, bilateral, profound, sudden hearing loss. magnetic resonance imaging showed bilateral high signal within the cochlea, vestibule, and portions of the semicircular canals on the non-enhanced t1-weighted images, most consistent with recent hemorrhage into the otic labyrinth. serum analysis and bone-marrow biopsy led to diagnosis of waldenstrom's macroglobulinemi ... | 2006 | 27298688 |
| limits to the criminal law in healthcare. | the secretary of state for health, virginia bottom-ley, made it clear recently at the conference of the national association for health authorities and trusts that it was not her intention to bring in a law to make it a criminal offence to pass on the human immunodeficiency virus (hiv). this statement followed the news report that a man in birmingham was alleged to have infected several women with the virus. he was aware of his condition because, as a haemophiliac, he had received compensation a ... | 1992 | 27858483 |
| adult day care for people with human immunodeficiency virus. | the human immunodeficiency virus (hiv) adult day care adc) center is an important component in the continuum of care for the hiv ill client, providing therapeutic advantages to the client and administrative advantages to the community as it copes with the growing hiv epidemic. the hiv adc center was designed using several models of adult day programs for developmental, psychosocial, geriatric and neuropsychiatric treatment. the hiv adc client is typically in a non-acute phase of a chronic disabi ... | 1991 | 23931179 |
| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |