| early-developed hand osteoarthritis in treated hiv-positive patients: four cases. | we describe four cases of hand osteoarthritis in patients with hiv infection under antiretroviral treatment. a 36-year-old hiv-infected man came for consultation in 2007 with hand osteoarthritis. he was diagnosed hiv positive by sexual transmission in 1997. a 52-year-old hiv-infected woman came for consultation with hand osteoarthritis started in 2006. she was diagnosed hiv positive in 1986 by sexual transmission. a 57-year-old man presented hand osteoarthritis. this former iv drug user was diag ... | 2015 | 26184535 |
| influence of partner type on acceptability and likelihood of use of a rectal microbicide among young men who have sex with men in the united states and puerto rico. | this study examined how acceptability of placebo gel with receptive anal intercourse (rai) and likelihood of future rectal microbicide use varied across partner types. because no rectal microbicide is available yet, use of placebo permitted the study of gel use behavior in real-life circumstances. a total of 87 men who have sex with men (msm) aged 18 to 30 years inserted placebo gel rectally before rai during 12 weeks. using mixed-methods design, participants completed a behavioral questionnaire ... | 2017 | 26132717 |
| acute coronary syndrome in hiv naïve patient with low cd4 count and no other significant risk factors: case report and literature review. | coronary artery disease (cad) has become the leading cause of mortality in patients with human immunodeficiency virus (hiv). the typical hiv-infected patient presenting with acute coronary syndrome (acs) is a man in his mid to late 40s. the most common presentation is an acute myocardial infarction (mi), most often with st segment elevation. coronary anatomy seems to be variable, with some studies showing a higher prevalence of single-vessel disease and others showing a higher prevalence of 2- a ... | 2017 | 26065032 |
| immune reconstitution inflammatory syndrome in a patient with progressive multifocal leukoencephalopathy. | progressive multifocal leukoencephalopathy (pml) is a severe opportunistic infection of the central nervous system. a 52-year-old man with hiv infection, recently started on antiretroviral therapy, presented with symptoms of mental cloudiness, blurry vision and ataxia. mri of the brain showed nodular perivascular space enhancement with surrounding vasogenic oedema and midline shift. a lumbar puncture revealed non-inflammatory cerebrospinal fluid and was positive for jc virus. as the patient deve ... | 2015 | 26063110 |
| [a case of kaposi's sarcoma of the rectum presenting with hematochezia and rectal pain]. | a man in his 20s was referred to our hospital with hematochezia and rectal pain. total colonoscopy revealed a reddish, protruding, ulcerated lesion occupying approximately half of the luminal circumference of the rectum. examination of biopsy specimens showed proliferating spindle cells infiltrating the lamina propria, a finding consistent with kaposi's sarcoma. the patient was also found to be anti-human immunodeficiency virus (hiv) antibody positive;therefore, we diagnosed acquired immunodefic ... | 2015 | 26050727 |
| crf01_ae/b/c, a novel drug-resistant hiv-1 recombinant in men who have sex with men in beijing, china. | we report a unique hiv-1 recombinant strain (urf) from an hiv-positive man who has sex with men (msm) in beijing, china. this virus genome has insertions and multiple drug-resistant mutations to both nucleoside reverse transcriptase inhibitors (nrtis) and nonnucleoside reverse transcriptase inhibitors (nnrtis), as well as a complex intersubtype recombinant structure with 11 breakpoints. phylogenetic analysis of the near full-length genome (nflg) shows that this urf is comprised of gene regions o ... | 2015 | 25962473 |
| neurogenic pulmonary edema following cryptococcal meningoencephalitis associated with hiv infection. | neurogenic pulmonary edema (npe) is a clinical syndrome characterized by the acute onset of pulmonary edema following a significant central nervous system insult. only a few cases of npe after cryptococcal meningitis have been reported. we report a case of npe following cryptococcal meningoencephalitis. a 40-year-old man with no medical history was hospitalized for disturbance of consciousness. blood glucose level was 124 mg/dl. non-contrast head computed tomography showed no abnormalities. lumb ... | 2015 | 25955768 |
| mucocutaneous presentation of kaposi sarcoma in an asymptomatic human immunodeficiency virus-positive man. | kaposi sarcoma (ks) is a malignant proliferation of endothelial cells within the skin. the clinical presentation is characterized by clusters of violaceous macules and papules that often appear on the distal extremities or trunk with or without oral mucosal involvement. mucocutaneous lesions are present at onset of diagnosis in a minority of cases. the lesions can evolve to include the mucous membranes of the gastric mucosa and the lungs. we present a unique case of ks in a 45-year-old, asymptom ... | 2015 | 25942034 |
| a case of cerebellar dysarthria as the presenting symptom of hiv infection. | a 37 year old man presented with progressive dysarthria for 2 weeks. a week later he developed ataxia and bilateral cerebellar signs including intention tremors, dysmetria and dysdiadokokinesia. during evaluation for aetiology of cerebellar dysarthria, mri brain revealed asymmetric altered signal intensities in bilateral cerebellar hemispheres and right side of pons suggesting demyelinating lesions. elisa for human immune deficiency virus-1 was positive. we kept a presumptive diagnosis of progre ... | 2014 | 25856948 |
| high hiv prevalence and incidence among msm across 12 cities in india. | to characterize prevalence, incidence, and associated correlates of hiv infection among msm in 12 cities across india. | 2015 | 25849835 |
| disseminated penicillium marneffei mimicking paradoxical response and relapse in a non-hiv patient with pulmonary tuberculosis. | clinical deterioration during the treatment of tuberculosis remains a diagnostic challenge. we describe the case of a 46-year-old man with a history of oral cancer status after a radical operation who had pulmonary tuberculosis with pleura and neck lymph node involvement. the clinical condition improved after antituberculosis therapy. however, the patient suffered from low-grade fever, progressive dyspnea, and cough after 7 weeks of the therapy. the findings of chest plain films were relapse and ... | 2015 | 25823679 |
| a case of hpv and acquired genital lymphangioma: over-lapping clinical features. | lymphatic malformation or lymphangioma is a benign proliferation of the lymphatics accounting for 4% of all vascular malformations and 26% of all benign vascular tumors. there are several reports about genital lymphangiomas mimicking venereal lesions, such as genital warts. hereby we described a case of a 24 year old man affected by multiple vesicles and warts in genital area. all hematological and biochemical parameters, human immunodeficiency virus (hiv) and treponema pallidum tests, c1-inhibi ... | 2015 | 25818349 |
| corticoid therapy for overlapping syndromes in an hiv-positive patient. | human immunodeficiency virus (hiv) infection disturbs the host's immune function and often coexists with various autoimmune and/or systemic rheumatic diseases with manifestations that sometimes overlap with each other. we herein present the case of a 43-year-old japanese man infected with hiv who exhibited elevated serum creatine kinase and transaminases levels without any symptoms. he was diagnosed with autoimmune hepatitis, polymyositis and sjögren's syndrome and received combined antiretrovir ... | 2015 | 25743017 |
| complete remission of primary hepatic lymphoma in a patient with human immunodeficiency virus. | diffuse large b cell primary hepatic lymphoma is a rare disease with limited available information regarding treatment strategy. although the liver contains lymphoid tissue and is an important site for lymphocytes activation, primary hepatic lymphoma is rare. host factors make the liver a poor environment for malignant lymphoma development. its coexistence with human immunodeficiency virus (hiv) infection increases morbidity and mortality risks. additionally, jaundice increases chances of develo ... | 2015 | 25685766 |
| semen decontamination for the elimination of seminal hiv-1. | the risk of human immunodeficiency virus (hiv) transmission to the female partner, or potential offspring of an hiv-1 infected man can be reduced using semen decontamination procedures before assisted reproductive treatment (art). the objective of this study was to determine the efficiency of decontaminating semen samples (n = 186) from 95 hiv-1 sero-positive patients. aliquots of neat semen were submitted for viral validation by qualitative and quantitative polymerase chain reaction. semen samp ... | 2015 | 25596908 |
| internal carotid artery stenosis associated with giant cell arteritis: case report and discussion. | cerebrovascular ischemic events associated with giant cell arteritis (gca) are uncommon and have been reported in 3%-4% of patients. we describe a case report of gca associated with intracranial stenosis and review various angiographic findings. | 2014 | 25566338 |
| experiences of social oppression among men who have sex with men in a cosmopolitan city in nigeria. | in several african countries, men who have sex with men (msm) are becoming visible, as a result of which they are now victims of human rights violations. this has a negative effect on their ability to access services targeted at human immunodeficiency virus (hiv) prevention and care. the main objective of this study was to document the experiences of social oppression among msm in lagos state, nigeria. | 2015 | 25565899 |
| diffuse large b-cell lymphoma solely involving bilateral adrenal glands and stomach: report of an extremely rare case with review of the literature. | a 60-year-old man complained of nausea, vomiting, decreased appetite, and a feeling of abdominal fullness in august 2013. based on biopsy findings from an upper gastrointestinal endoscopy examination, a diagnosis of non-hodgkin's lymphoma (nhl), diffuse large b-cell lymphoma (dlbcl), non-gc type, was made. f18-fluorodeoxyglucose-positron emission tomography/computed tomography (fdg-pet/ct) revealed abnormal accumulations solely in the gastric wall (suvmax = 14.5), the left adrenal gland (suvmax ... | 2014 | 25550871 |
| the annual american men's internet survey of behaviors of men who have sex with men in the united states: protocol and key indicators report 2013. | men who have sex with men (msm) are disproportionately affected by human immunodeficiency virus (hiv) and there is evidence that this population is participating in increasingly risky sexual behavior. these changes are occurring in the context of new modes of online social interaction-many msm now report first meeting their sex partners on the internet. better monitoring of key behavioral indicators among msm requires the use of surveillance strategies that capitalize on these new modes of inter ... | 2017 | 27227126 |
| human herpes virus-8-associated multicentric castleman's disease in an hiv-positive patient presenting with relapsing and remitting hyponatraemia. | we report a case of human herpes virus-8-associated multicentric castleman's disease in an hiv-positive patient with hyponatraemia. a 65-year-old man was admitted with relapsing and remitting fever, scattered skin eruptions and hepatosplenomegaly following combination antiretroviral therapy for his hiv infection. based on histopathological findings, he was diagnosed as having human herpes virus-8-associated multicentric castleman's disease and was treated with four-weekly infusions of rituximab. ... | 2015 | 25504830 |
| development of primary central nervous system lymphoma associated with human immunodeficiency virus and jc virus infection. | we report here a case of a 37-year-old man with human immunodeficiency virus (hiv) infection followed by jc virus (jcv) infection and primary central nervous system lymphoma (pcnsl). the patient had been infected with hiv type 1 due to blood products for hemophilia a during infancy. he had progression of nervous symptoms and was diagnosed with progressive multifocal leukoencephalopathy (pml) clinically at the age of 36, when his cd4-positive lymphocyte counts ranged between 350 and 450/μl. oral ... | 2014 | 25501112 |
| adaptation of an hiv medication adherence intervention for adolescents and young adults. | rising rates of human immunodeficiency virus (hiv) infection among adolescents and young adults underscore the importance of interventions for this population. while the morbidity and mortality of hiv has greatly decreased over the years, maintaining high rates of adherence is necessary to receive optimal medication effects. few studies have developed interventions for adolescents and young adults and none have specifically been developed for sexual minority (lesbian, gay, and bisexual; lgb) you ... | 2014 | 25452680 |
| sociobehavioral correlates of hiv risk among men who have sex with men in chhattisgarh, india: analysis of sentinel surveillance data. | men who have sex with men (msm) in india are mostly hidden due to stigma and discrimination and are at a higher risk of acquiring human immunodeficiency virus (hiv). hiv sentinel surveillance (hss) reported an increased hiv burden in chhattisgarh, an important state in central india. this state has the distinction of having the highest hiv prevalence among msm in india; therefore, it warrants special attention; hence, we focused on the role of msm in the hiv epidemic in this state. cross-section ... | 2015 | 25420644 |
| case 212: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. | history a previously healthy 23-year-old white man presented to the emergency department of our hospital with a 2-month history of dysarthria, progressively worsening vertigo, and difficulty walking. a diagnosis of retinitis pigementosa was made in this patient's childhood. he did not have any history of congenital syphilis. he did not have a history of nausea or vomiting, fever, weight loss, headache, photophobia, seizure, extremity weakness, or sensory disturbance. physical examination reveale ... | 2014 | 25420171 |
| [hiv window period. acute retroviral syndrome]. | a 24-year-old man with no significant medical history was admitted to this hospital because of an acute exanthema, myalgia and malaise. a fourth-generation screening test for hiv was reactive but the following confirmation test was not. although the patient did not belong to a high risk group, we decided to perform a hiv-rna-pcr. the result showed a high virus load so that we finally diagnosed a primary hiv infection. | 2015 | 25410826 |
| hepatitis associated aplastic anemia: case report and discussion. | aplastic anemia (aa) is thought to represent an autoimmune disorder leading to generation of activated cd8+ t-cells that target the bone marrow precursors. hepatitis associated aplastic anemia (haaa) is a subtype of aplastic anemia that develops within several months ofan episode of acute hepatitis. etiologic agents include hepatitis viruses (a-e and g), epstein-bar virus, cytomegalovirus, hiv, parvovirus b19, and echoviruses amongst others. however, most haaa cases are labeled "idiopathic" as t ... | 2014 | 25314890 |
| clinical case of the month. a 44-year-old hiv-infected man with righ-shoulder swelling. | immunocompromised patients are susceptible to various joint infections with less-common pathogens, such as mycobacterium. physicians should have a low threshold to investigate the cause of an arthropathy further. an aspiration of the effusion is usually warranted to identify the possible pathogen and target treatment. we report an unusual presentation of a human immunodeficiency virus-infected patient with a chronic effusion arthropathy of his right shoulder due to mycobacterium kansasii. we rev ... | 2017 | 25311464 |
| paracoccidioidomycosis simulating brain tumor. | paracoccidioidomycosis (pcm) is a systemic granulomatous disease caused by paracoccidioides brasiliensis. involvement of the central nervous system (cns) occurs in about 10% of cases. | 2014 | 25298916 |
| transcranial doppler sonography: atypical dicrotic pulse waveforms in a man with hiv infection and severe cardiomyopathy. | a 27-year-old human immunodeficiency virus--positive man presented with abdominal pain. computed tomography of the abdomen revealed large right pleural effusion, pericardial effusion and marked ascites with diffuse intra- and extraperitoneal lymphadenopathy. echocardiography showed severely reduced left ventricular systolic function. after drainage of pleural and pericardial fluid, the patient developed severe hypotension and hypoxic respiratory failure. extra- and intracranial neurovascular son ... | 2017 | 25289479 |
| impact of hiv on and the constructions of masculinities among hiv-positive men in south africa: implications for secondary prevention programs. | to date, whilst there have been many published studies exploring the links between masculinity and hiv, not much work has been done to explore how an hiv-positive diagnosis impacts men's sense of masculinity and contextualizing the masculinities as fluid and changing. | 2014 | 25280735 |
| disseminated kaposi's sarcoma-a missed diagnosis. | kaposi's sarcoma is significantly prevalent among men infected with the human immunodeficiency virus, accounting for >90% of all cases. the early presentation of ks typically involves mucocutaneous lesions and lymphadenopathy, and more advanced disease can affect the lungs and other organs. | 2014 | 25256409 |
| bullous systemic lupus erythematosus in a patient with human immunodeficiency virus infection: a paradox of autoimmunity and immunodeficiency. | bullous lupus erythematosus is a rare variant of systemic lupus erythematosus (sle) and is characterized by autoantibodies to type vii collagen. co-existence of sle and human immunodeficiency virus (hiv) infection is extremely rare; the development of bullous lupus in the setting of hiv has been, to our knowledge, reported in the literature only once. we describe a 26-year-old man with an 8-year history of hiv infection who developed bullous sle. the patient presented with widespread, tense bull ... | 2014 | 25244171 |
| blepharoptosis and haart related mitochondrial myopathy. | to report a case of blepharoptosis in a patient with human immunodeficiency virus (hiv) on highly active antiretroviral therapy (haart) with biopsy confirmed mitochondrial deletions consistent with haart related myopathy. | 2014 | 25215893 |
| hypogonadism in the hiv-infected man. | androgen deficiency occurs frequently in men with human immunodeficiency virus (hiv) infection. antiretroviral treatments had reduced the prevalence of male hypogonadism. the pathogenesis of testosterone (t) deficiency in hiv is multifactorial. several mechanisms have been proposed; among them, drugs, fat redistribution, and a poor health status could explain the mechanism leading to gonadotropins inhibition and hypogonadotropic hypogonadism. the diagnosis of hypogonadism in hiv-infected men sho ... | 2014 | 25169563 |
| a case of secondary syphilis demonstrating nephrotic syndrome and a solitary intrahepatic mass in a human immunodeficiency virus-1-infected patient. | a 37-year-old, human immunodeficiency virus-1-infected japanese man was referred because of nephrotic syndrome following emergence of generalized skin rash. serological tests for syphilis turned out to be positive within ten months of the referral. abdominal echography incidentally revealed a solitary intrahepatic mass without a detectable blood flow in segment 7. the patient's signs and symptoms, as well as the intrahepatic mass, resolved promptly after administration of amoxicillin. we conside ... | 2015 | 25127155 |
| a case of lupus-like glomerulonephritis in an hiv patient with nephrotic range proteinuria, purpura, and elevated iga level. | human immunodeficiency virus (hiv) infection is growing medical concern worldwide. there are many types of glomerulonephritis which are associated with hiv infection. we report a case of a 53-year-old korean man with an hiv infection, who was developed nephritic range proteinuria and purpura with elevated iga level rasing a possibility of henoch-schölein purpura (h-s purpura). however, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic ... | 2014 | 25120835 |
| paradoxical reaction to antituberculosis therapy in a patient with lupus vulgaris. | patients receiving treatment for tuberculosis may experience an unexpected deterioration of their disease; this is known as a paradoxical reaction. we present the case of a 59-year-old man with lupus vulgaris who experienced a paradoxical deterioration of cutaneous lesions after starting antituberculosis therapy. the reaction was self-limiting; the lesions gradually improved, and the final outcome was very good. paradoxical reactions are well-known in patients with human immunodeficiency virus ( ... | 2015 | 25089032 |
| fatal disseminated cryptococcosis resembling miliary tuberculosis in a patient with hiv infection. | a 51-year-old man was transferred to our hospital due to acute respiratory failure that had progressed over four days. a chest x-ray and thoracic computed tomography scan showed multiple faint micronodules randomly distributed throughout both lungs with ground glass opacity, suggesting miliary tuberculosis or pneumocystis jirovecii pneumonia with acute respiratory distress syndrome. six hours after admission, the patient died of septic shock. later, the cryptococcal antigen titer was found to be ... | 2014 | 25088878 |
| a case of severe hiv-associated psoriasis successfully treated with acitretin therapy. | psoriasis is a chronic inflammatory skin disease that involves immune-mediated cutaneous inflammation and keratinocyte hyperproliferation. psoriasis in patients with hiv responds poorly to treatment and has a high morbidity rate, thus posing a challenge to clinicians. until now, there have been no documented cases of acitretin therapy for hiv-associated psoriasis in korea. here, we report a case of safe and successful therapy with acitretin in a 52-year-old man with hiv-associated psoriasis that ... | 2014 | 25024875 |
| [construction of recombinant over expression vector of penk gene and the function study of penk gene]. | to construct recombinant over expression vector of homo sapiens proenkephalin (penk) gene and explore the function of penk gene. | 2014 | 24941803 |
| pulmonary mucormycosis due to lichtheimia ramosa in a patient with hiv infection. | mucormycosis is increasingly common in patients with risk factors such as diabetes mellitus, neutropenia, and corticosteroid therapy. however, mucormycosis seems to be less common in patients with human immunodeficiency virus (hiv) infection compared to patients with other risk factors. despite their lower virulence, lichtheimia species should be regarded as emerging pathogens among mucoralean fungi. we report a fatal case of pulmonary mucormycosis due to lichtheimia ramosa in a 52-year-old man ... | 2014 | 24925144 |
| human immunodeficiency virus testing pitfalls and clinical suspicion. | universal human immunodeficiency virus (hiv) screening was recommended in 2012, and major improvements in hiv testing have occurred in the past decade, but identification of hiv infected individuals remains inadequate in the united states. we report the case of a seronegative hiv-infected man who despite clinical and laboratory findings of acquired immunodeficiency syndrome,repeatedly tested nonreactive to third-generation hiv enzyme immunoassays (eias) and western blot testing. serologic diagno ... | 2014 | 24856744 |
| sexual behaviour and condom use as a protection against sexually transmitted infections in student population. | the aim of the study was to determine the differences in sexual behaviour and condom use as a protection against sexually transmitted infections (sti) between the first-year and the last-year students. data were collected by filling anonymous and consented questionnaire in june of 2011 at university of josip juraj strossmayer in osijek, croatia. out of 857 students in the planned sample, 462 (53.9%) filled out the questionnaire, and 353/462 (76.4%) were sexually active. data from sexually active ... | 2014 | 24851594 |
| acute coronary thrombosis and multiple coronary aneurysms in a 22-year-old man with the human immunodeficiency virus. | the human immunodeficiency virus (hiv) can cause diverse cardiovascular complications. in hiv patients on antiretroviral therapy, the prevalence of myocardial infarction has steadily increased over the years. young patients who are naïve to antiretroviral therapy and who experience coronary events are not well represented in the medical literature. we describe the case of a 22-year-old man, infected with hiv for 4 years and never treated with antiretroviral therapy, who emergently presented with ... | 2014 | 24808786 |
| pyoderma gangrenosum successfully treated with antiretroviral therapy alone in a human immunodeficiency virus-infected individual. | we report a case of a 60-year-old man infected with human immunodeficiency virus (hiv) who was transferred to our hospital for management of multiple non-healing, painful ulcers on the lower extremities. the histological findings of the biopsy specimen were compatible with the diagnosis of pyoderma gangrenosum (pg). an association between hiv infection and the development of pg was considered after a thorough investigation. antiretroviral therapy without the use of adjunctive immunosuppressive a ... | 2014 | 24767463 |
| ostraceous and inverse psoriasis with psoriatic arthritis as the presenting features of advanced hiv infection. | knowledge of both the common and atypical presentations of human immunodeficiency virus (hiv)-associated dermatoses may be helpful in arousing suspicion of hiv, especially in patients with no reported risk factors. herein, we report the case of an otherwise healthy, nonpromiscuous 29-year-old man who presented to our institution with an eight-week history of plaques with oyster shell-like scales on the trunk, extremities and genital area. the plaques were associated with fever, and intermittent ... | 2014 | 24763845 |
| a case of severe thrombocytopaenia associated with acute hiv-1 infection. | a 23-year-old man was admitted to our hospital with severe thrombocytopaenia. he had unprotected sexual contact 6 weeks earlier. he was diagnosed with acute hiv infection by means of hiv rna viral load testing and hiv-associated thrombocytopaenia. although his thrombocytopaenia improved immediately with short-term dexamethasone therapy, this effect was not sustained after cessation of therapy. antiretroviral therapy including raltegravir was initiated, and the patient recovered from severe throm ... | 2015 | 24737880 |
| hyperthyroidism caused by acquired immune deficiency syndrome. | acquired immune deficiency syndrome (aids) is an immune deficiency disease. the etiology of hyperthyroidism, which can also be immune-related, is usually divided into six classical categories, including hypophyseal, hypothalamic, thyroid, neoplastic, autoimmune and inflammatory hyperthyroidism. hyperthyroidism is a rare complication of highly active antimicrobial therapy (haart) for human immunodeficiency virus (hiv). hyperthyroidism caused directly by aids has not been previously reported. | 2014 | 24706313 |
| alopecia areata and vitiligo as primary presentations in a young male with human immunodeficiency virus. | a 26-year-old chinese male consulted with the team regarding his alopecia areata and vitiligo for which previous treatment was ineffective. the patient, a homosexual man, denied having a history of drug abuse and of blood transfusion. no member of his family had vitiligo or alopecia. laboratory studies revealed that the serum for anti-human immunodeficiency virus (hiv) antibody was positive. the patient's cd4 lymphocyte count and cd4/cd8 ratio were both strikingly low (20 cells/ml and 0.04), but ... | 2014 | 24700956 |
| cryptococcal meningitis in a multiple sclerosis patient taking natalizumab. | natalizumab was approved in 2004 by the us food and drug administration (us-fda) for treatment of multiple sclerosis (ms), however it was temporarily withdrawn after its use was associated with progressive multifocal leukoencephalopathy (pml). other reported adverse events have included melanoma, primary central nervous system (cns) lymphoma, and gastrointestinal cryptosporidiosis. an ms exacerbation may occur after discontinuation and immune reconstitution inflammatory syndrome (iris), particul ... | 2014 | 24680560 |
| immune reconstitution inflammatory syndrome in acquired immune deficiency syndrome related to cryptococcal meningoencephalitis. | background. highly active antiretroviral therapy (haart) has contributed to reducing the occurrence of opportunistic infections and mortality in human immunodeficiency virus (hiv) infected patients. however, a paradoxical worsening of clinical signs and symptoms among patients during haart may occur. immune reconstitution inflammatory syndrome (iris) is described as a paradoxical deterioration of clinical status on initiation of haart in patients with hiv infection. case report. we describe the ... | 2017 | 26425608 |
| tenofovir, emtricitabine, and darunavir/ritonavir pharmacokinetics in an hiv-infected patient after roux-en-y gastric bypass surgery. | to determine antiretroviral (arv) pharmacokinetics in a patient who previously underwent roux-en-y gastric bypass (rygb) surgery. | 2014 | 24615629 |
| the health-care needs of the older gay man living with hiv. | human immunodeficiency virus (hiv) was once thought of as a condition predominately affecting the young. however, hiv among the older population is increasing. older gay male adults living with hiv have received little attention from those who provide and commission services. however, with effective treatment those gay men aged over 50 are the fastest growing group of people with hiv in the u.k. nurses will be required to offer care in a number of ways to this cohort of patients. in so doing, nu ... | 2013 | 24471216 |
| severe recurrence of drug rash with eosinophilia and systemic symptoms syndrome secondary to rifampicin patch testing in a human immunodeficiency virus-infected man. | | 2014 | 24450829 |
| a case report of hearing loss post use of hydroxychloroquine in a hiv-infected patient. | a case with reversible symmetrical sensorineural hearing loss following hydroxychloroquine therapy is described. | 2014 | 24450358 |
| a cross-sectional assessment of the burden of hiv and associated individual- and structural-level characteristics among men who have sex with men in swaziland. | similar to other southern african countries, swaziland has been severely affected by hiv, with over a quarter of its reproductive-age adults estimated to be living with the virus, equating to an estimate of 170,000 people living with hiv. the last several years have witnessed an increase in the understanding of the potential vulnerabilities among men who have sex with men (msm) in neighbouring countries with similarly widespread hiv epidemics. to date, there are no data characterizing the burden ... | 2013 | 24321117 |
| hiv-associated burkitt lymphoma in a japanese patient with early submandibular swelling. | patients infected with the human immunodeficiency virus (hiv) are at risk of developing malignancies and have an increased susceptibility to infection. hiv-associated burkitt lymphoma (bl) is relatively rare in developed countries, but remains prevalent in developing counties and is sometimes compounded by the fact that patients may be unaware that they are hiv-positive. | 2013 | 24370065 |
| epidermodysplasia verruciformis in a young man with hiv since birth--case report. | epidermodysplasia verruciformis is a genodermatosis characterized by susceptibility to infection by specific hpv types (hpv 3/10 and beta-hpvs). it is considered to be the first model in human carcinogenesis induced by hpv. in this report we present a rare case of epidermodysplasia verruciformis associated with vertical transmission of hiv. although most patients with hiv present infections by hpv virus, the frequency of epidermodysplasia verruciformis is no greater in patients with hiv because ... | 2015 | 24346916 |
| [case of serious hiv-associated nephropathy resulting in the introduction of hemodialysis]. | a previously healthy 46-year-old black man visited the other hospital because of fever, appetite loss and nausea. renal dysfunction, liver injury, and a highly markedly elevated ldh level were found. abdominal ct demonstrated enlarged liver, spleen, kidney and lymph nodes. human immunodeficiency virus (hiv) was serologically positive. his serum bun, creatinine and potassium were 74.9 mg/dl, 11.78 mg/dl, and 5.6 meq/l, respectively. after admission, anuria persisted and the progression of renal f ... | 2013 | 24288971 |
| rapidly progressive cerebellar ataxia in west wales. | progressive multifocal leucoencephalopathy (pml) is a severe demyelinating disease of the central nervous system that is caused by the jc virus infection. it is often fatal or severely disabling. pml exclusively happens in the context of cell-mediated immunosuppression. prior to the era of hiv, pml was mainly confined to patients with haematological malignancies and rheumatological diseases. the hiv epidemic in the early eighties led to massive expansion in the incidence and prevalence of the di ... | 2013 | 24265345 |
| seizure as an initial presentation of human immunodeficiency virus: acute toxoplasmosis mimicking glioblastoma multiforme. | we present a case of a 46-year-old man with a history significant only for hypertension and depression that presented with a new onset seizure resulting from a right parietal lobe mass. further evaluation determined the parietal mass to be central nervous system toxoplasmosis, which was the initial presentation of his underlying hiv/aids. this case provided a diagnostic challenge and demonstrates the importance of a thorough evaluation as it pertains to a newly diagnosed brain lesion. | 2013 | 24234430 |
| adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin c deficiency. | a 20-year-old man was hospitalized for malignant hypertension, mechanical hemolysis, and kidney failure. kidney biopsy confirmed glomerular and arteriolar thrombotic microangiopathy. etiologic analyses, which included adamts13 activity, stool culture, complement factor proteins (c3, c4, factor h, factor i, and mcp [membrane cofactor protein]), anti-factor h antibodies, hiv (human immunodeficiency virus) serology, and antinuclear and antiphospholipid antibodies, returned normal results. malignant ... | 2014 | 24210589 |
| anal carcinoma and hiv infection: is it time for screening? | a 38-year-old white man had a 10-year history of human immunodeficiency virus (hiv) infection (a3), with no episodes of opportunistic diseases and in good immunologic recovery (cd4 cell count: 450 and indetectable hiv viral load) while on haart. he presented with a two-month history of mild anal symptoms, including pruritus and episodic bleeding. he referred past episodes of anal warts, self-treated with several topical compounds, all proven unsuccessful. perianal examination showed erythema and ... | 2014 | 24139082 |
| atazanavir and chest pain. | we present a case of a 41-year-old man complaining of chest pain, which he directly attributed to his antiretrovirals, specifically atazanavir and ritonavir. the chest pain resolved on stopping the treatment, and recurred when atazanavir was restarted, again resolving on discontinuation. cardiovascular risk factors are an important consideration with any antiretroviral therapy but particularly with protease inhibitors. the association between atazanavir and cardiac arrhythmias has been reported ... | 2014 | 24108452 |
| syphilis, leprosy, and human immunodeficiency virus coinfection: a challenging diagnosis. | the association between syphilis, leprosy, and human immunodeficiency virus (hiv) is not well documented, and the emergence of isolated cases raises the interest and indicates that this triple coinfection can occur. we report the case of a 42-year-old man from rio de janeiro, brazil, who presented with erythematous papules on the trunk, back, and upper and lower extremities; an erythematous plaque on the upper abdomen; and an erythematous violaceous plaque on the right thigh with altered sensiti ... | 2013 | 24087779 |
| clinical activity of lenalidomide in visceral human immunodeficiency virus-related kaposi sarcoma. | curative treatment of aggressive kaposi sarcoma (ks) with conventional chemotherapy in human immunodeficiency virus (hiv)-infected patients remains difficult. the administration of thalidomide, an immunomodulatory drug with antiangiogenic effects, is limited by its toxicity. this engenders interest in evaluating thalidomide analogues such as lenalidomide with better toxicity profiles. to our knowledge, we describe for the first time a patient with visceral ks successfully treated with lenalidomi ... | 2013 | 24080749 |
| relevance of udp-glucuronosyltransferase polymorphisms for drug dosing: a quantitative systematic review. | udp-glucuronosyltransferases (ugt) catalyze the biotransformation of many endobiotics and xenobiotics, and are coded by polymorphic genes. however, knowledge about the effects of these polymorphisms is rarely used for the individualization of drug therapy. here, we present a quantitative systematic review of clinical studies on the impact of ugt variants on drug metabolism to clarify the potential for genotype-adjusted therapy recommendations. data on ugt polymorphisms and dose-related pharmacok ... | 2014 | 24076267 |
| a diagnostic dilemma: drug-induced aseptic meningitis in a 45-year-old hiv-positive man. | we describe a case of aseptic meningitis following the administration of moxifloxacin in a 45-year-old man with human immunodeficiency virus (hiv). at presentation he was receiving tuberculosis treatment on a modified regimen following severe hepatotoxicity; this included moxifloxacin, started 8 days previously. initial cerebrospinal fluid (csf) analysis was grossly abnormal. anti-viral and -bacterial treatments were started. all microbiological tests proved negative and his moxifloxacin was wit ... | 2014 | 23999938 |
| primary hepatic circumscribed burkitt's lymphoma that developed after acute hepatitis b: report of a case with a review of the literature. | a japanese man aged 30 years old contracted acute hepatitis b in october 2011, and was cured following conservative treatment. mild hepatosplenomegaly was the only positive finding on computed tomography (ct) and ultrasonography at that time. in may 2012, slight impairment of the liver function was detected again in the patient; an abdominal ct at this time revealed a tumor mass in the right hepatic lobe, so subsegmentectomy of the right hepatic lobe was performed. on the basis of the findings o ... | 2013 | 23995115 |
| the transmembrane protein of the human endogenous retrovirus--k (herv-k) modulates cytokine release and gene expression. | numerous copies of endogenous retroviruses are present in the genome of mammals including man. although most of them are defective, some, e.g., the human endogenous retroviruses herv-k, were found to be expressed under certain physiological conditions. for instance, herv-k is expressed in germ cell tumours and melanomas as well as in the placenta. most exogenous retroviruses including the human immunodeficiency virus hiv-1 induce severe immunodeficiencies and there is increasing evidence that th ... | 2013 | 23950929 |
| [ophthalmological alterations at the initial diagnosis of hiv infection]. | acquired immunodeficiency syndrome (aids) caused by the human immunodeficiency virus (hiv), is one of the most important infectious causes of death in the twentieth and twenty-first centuries. ocular manifestations can appear in particular when the cd4 cell count is low. this article presents a case report of a 38-year-old homosexual man in whom hiv microangiopathy retinopathy syndrome (maps) was found during the assessment of the initial hiv diagnosis. typical findings in maps are conjunctival ... | 2014 | 23948735 |
| trimethoprim-associated hyponatremia. | hyponatremia associated with diuretic use can be clinically difficult to differentiate from the syndrome of inappropriate antidiuretic hormone secretion (siadh). we report a case of a 28-year-old man with hiv (human immunodeficiency virus) and pneumocystis pneumonia who developed hyponatremia while receiving trimethoprim-sulfamethoxazole (tmp/smx). serum sodium level on admission was 135 meq/l (with a history of hyponatremia) and decreased to 117 meq/l by day 7 of tmp/smx treatment. in the setti ... | 2013 | 23891358 |
| the effects of non-synonymous single nucleotide polymorphisms (nssnps) on protein-protein interactions. | non-synonymous single nucleotide polymorphisms (nssnps) are single base changes leading to a change to the amino acid sequence of the encoded protein. many of these variants are associated with disease, so nssnps have been well studied, with studies looking at the effects of nssnps on individual proteins, for example, on stability and enzyme active sites. in recent years, the impact of nssnps upon protein-protein interactions has also been investigated, giving a greater insight into the mechanis ... | 2013 | 23867278 |
| gingival anaplastic large-cell lymphoma mimicking hyperplastic benignancy as the first clinical manifestation of aids: a case report and review of the literature. | this paper presents an unusual case of gingival alcl, which mimicked a benign hyperplastic lesion that occurred in a 57-year-old white man representing the first clinical manifestation of acquired immunodeficiency syndrome (aids). the patient was referred to the dental clinic of pucpr complaining of a lobulated nodule on the gingiva of his upper central incisors. the presence of advanced chronic periodontitis and dental plaque raised suspicion for a benignancy. an excisional biopsy was performed ... | 2013 | 23840974 |
| iatrogenic cushing syndrome in patients receiving inhaled budesonide and itraconazole or ritonavir: two cases and literature review. | to present two cases of iatrogenic cushing syndrome caused by the interaction of budesonide, an inhaled glucocorticoid, with ritonavir and itraconazole. | 2013 | 23807527 |
| plasmablastic lymphoma of the oral cavity in a human immunodeficiency virus-negative patient: a case report with literature review. | plasmablastic lymphoma (pbl) is an aggressive diffuse large b-cell lymphoma variant that is most frequently observed in the oral cavity of human immunodeficiency virus (hiv)-infected individuals. however, in recent years, some cases have emerged in patients without hiv infection and involve other sites like stomach, lung, nasal cavity, and jejunum. we report a rare case of pbl in the maxillary anterior area of a 62-year-old man without hiv infection. the tumor cells were characterized by non-coh ... | 2014 | 23791544 |
| stent-graft implantation for clinically diagnosed syphilitic aortic aneurysm in an hiv-infected patient. | we describe our experience with stent-graft placement in a patient with a clinically diagnosed syphilitic aortic aneurysm.the patient was a 43-year-old man with syphilitic and human immunodeficiency virus (hiv) co-infection. computed tomography (ct) revealed an aortic aneurysm with 89 mm in maximum size which was located at distal aortic arch and was considered syphilis derived saccular aneurysm. the aneurysm was judged at high risk of rupture from its shape. we decided to perform stent-graft im ... | 2014 | 23774613 |
| enhanced immune response against hiv-1 induced by a heterologous dna prime-adenovirus boost vaccination using mannosylated polyethyleneimine as dna vaccine adjuvant. | the heterologous deoxyribonucleic acid (dna) prime-adenovirus (adv) boost vaccination approach has been widely applied as a promising strategy against human immunodeficiency virus (hiv)-1. however, the problem of inefficient delivery and lack of specificity of dna vaccine remains a major issue. in this paper, to improve the transfection of dna vaccine and realize dendritic cell targeting, we used mannosylated polyethyleneimine (man-pei) as a dna vector carrier. | 2013 | 23690682 |
| rapid onset of rhabdomyolysis after switching to a raltegravir-based antiretroviral regimen. | raltegravir is the first integrase inhibitor antiretroviral agent that has been demonstrated to have antiviral efficacy and safety. however, the us food and drug administration has recommended use with caution in patients with risk factors for rhabdomyolysis, based on four case reports of rhabdomyolysis in patients with identifiable risk factors. we present a 32-year-old asian man with human immunodeficiency virus (hiv), but without other underlying diseases, who developed rapid-onset, raltegrav ... | 2016 | 23612027 |
| widening the differential for brain masses in human immunodeficiency virus-positive patients: syphilitic cerebral gummata. | a 39-year-old man with newly diagnosed human immunodeficiency virus (hiv) infection was admitted with right-sided weakness, right-sided vision loss and slurred speech, which worsened over several weeks. brain imaging revealed bilateral intraparenchymal ring-enhancing lesions and enhancement of the right optic nerve. serological findings were positive for venereal disease research laboratory test, whereas the cerebrospinal fluid venereal disease research laboratory test was nonreactive. brain bio ... | 2013 | 23588265 |
| leg weakness in a lung transplant patient. | progressive multifocal leukoencephalopathy (pml) is associated with jc polyomavirus (jcv) infection of central nervous system oligodendrocytes resulting in demyelinization and progressive focal neurologic deficits. reactivation of dormant jcv occurs in the setting of immunosuppression, most commonly in patients with human immunodeficiency virus (hiv)/acquired immunodeficiency syndrome (aids) or hematological malignancies. pml has also been reported in solid organ transplant recipients. we report ... | 2013 | 23582024 |
| clinical case of the month. a 50-year-old man with a persistent rash. | in september 2006, the united states centers for disease control and prevention (cdc) published updated recommendations for routine opt-out human immunodeficiency virus (hiv) testing in all healthcare settings. as late diagnosis of infection increases individual and societal risks, a goal of the 2010 national hiv/aids strategy is to increase the percentage of those aware of their infection. in 2008, two years following changes in the cdc testing recommendations, 44.6% of individuals 18-64 years ... | 2013 | 23550399 |
| acute human immunodeficiency virus (hiv) infection presenting with fever, elevated amylase/lipase, and hematologic abnormalities. | many cases of acute human immunodeficiency virus (hiv) infection (ahi) present to the emergency department (ed). early diagnosis allows a patient to modify their behavior and seek early treatment. the emergency physician should know that the antibody response may be absent. | 2013 | 23473815 |
| progressive multifocal leukoencephalopathy and idiopathic cd4 lymphocytopenia. | idiopathic cd4 lymphocytopenia (icl) is a syndrome described in patients with low counts of cd4 cells and no other causes for immunosuppression. a few cases of progressive multifocal leukoencephalopathy (pml) have been described in association with this entity. there is no effective treatment for any of them, and the clinical course and outcome are unpredictable. we report on a case of icl with pml and review the literature, trying to identify the clinical features and the prognosis clues associ ... | 2013 | 23465508 |
| disseminated mycobacterium avium complex infection in a patient carrying autoantibody to interferon-γ. | a 66-year-old man was admitted to our hospital on suspicion of lung cancer with bone metastasis. he suffered multiple joint and muscle pain. 18f-fluorodeoxy glucose positron emission tomography (fdg-pet) showed multiple accumulations in the lung, bones including the vertebrae, and mediastinal lymph nodes. anti-human immunodeficiency virus (hiv) antibody was negative. because mycobacterium avium complex (mac) was isolated from bronchial lavage fluid, bronchial wall, peripheral blood, and muscle a ... | 2013 | 23456204 |
| safe conception for hiv-discordant couples: insemination with processed semen from the hiv-infected partner. | the objective of the study was to evaluate the safety of semen washing with intrauterine insemination (sw-iui) for achieving pregnancy when the man is human immunodeficiency virus (hiv) infected and the woman is hiv negative. | 2013 | 23395921 |
| inadvertent provocative oral ondansetron use leading to toxic epidermal necrolysis in an hiv-infected patient. | toxic epidermal necrolysis (ten) is a severe cutaneous adverse reaction to drugs, characterized by extensive detachment of epidermis and mucous membranes with a mortality of 30-40%. an increased occurrence of cutaneous drug reactions is seen in patients with human immunodeficiency virus (hiv) infection. we present this case of ten caused by ondansetron in an hiv-infected patient. a 24-year-old hiv-1-infected man on antitubercular therapy and cotrimoxazole, presented with extensive and confluent ... | 2012 | 23248379 |
| toxic epidermal necrolysis caused by fluconazole in a patient with human immunodeficiency virus infection. | stevens-johnson syndrome and toxic epidermal necrolysis (ten) are rare but serious dermatologic disorders. these grave conditions present as medical emergency, requiring prompt diagnosis and management. these are often drug induced and various groups of drugs, such as sulfa drugs, nsaids, etc., have been implicated as to cause ten. fluconazole is a commonly used drug with mild side effects. ten caused by fluconazole is rare, and till now only few cases have been reported in the literature. we pr ... | 2012 | 23129968 |
| acquired immune-deficiency syndrome with focal onset of mycobacterium avium infection displaying a histological/genetic pattern of disseminated mycobacteria. | a 66-year-old man with human immunodeficiency virus (hiv) infection was admitted for treatment of pneumocystis pneumonia. upon admission, a tumor mass adjacent to the thoracic descending aorta was revealed on computed tomography. histology revealed an exudative granuloma with histiocytes packed with numerous acid-fast bacilli. mycobacterium avium was isolated from the tissue. a genetic examination of the isolates demonstrated this strain to be located in the cluster consisting of strains that ca ... | 2012 | 23124157 |
| giant condyloma acuminatum quickly growing: case report. | giant condyloma acuminatum (gca) is a rare, slow growing, large cauliflower tumor of the penile foreskin and perianal region with benign histologic appearance but high propensity for local invasion and recurrences. gca is associated with human papilloma virus (hpv) types 6 and 11 and it also has considerable risk of neoplastic transformation into fully invasive squamous cell carcinoma into about 5 years. | 2012 | 23095561 |
| hiv-associated multicentric castleman's disease. | multicentric castleman's disease (mcd) is a rare lymphoproliferative disorder. it is found with higher frequency in patients with hiv infection, with systemic symptoms and poor prognosis. we present the case of a 32-year old man with hiv disease, kaposi's sarcoma, lymphadenopathy, fever and hemolytic anemia. a diagnosis of castleman's disease is confirmed through biopsy and treatment is often based only on published case reports. systemic treatments for mcd have included chemotherapy, anti-herpe ... | 2012 | 23087796 |
| a case of adverse drug reaction induced by dispensing error. | to report about a case of acute renal failure due to absence of communication between physician and patient. | 2012 | 23084317 |
| carbohydrate recognition by the antiviral lectin cyanovirin-n. | cyanovirin-n (cvn) is a cyanobacterial lectin with potent antiviral activity and has been the focus of extensive preclinical investigation as a potential prophylactic for the prevention of the sexual transmission of the human immunodeficiency virus (hiv). here we present a detailed analysis of carbohydrate recognition by this important protein, using a combination of computational methods, including extensive molecular dynamics simulations and molecular mechanics/poisson-boltzmann surface area ( ... | 2012 | 23057413 |
| coadministration of tenofovir decreased atazanavir plasma concentration after unilateral nephrectomy. | we report a case in which the atazanavir (atv) concentration in the plasma decreased after unilateral nephrectomy in a patient receiving tenofovir (tdf). the patient was a 39-year-old man diagnosed with human immunodeficiency virus type 1 infection and was being treated with tdf/emtricitabine, atv, and ritonavir. before nephrectomy, atv and tdf plasma trough concentrations were 810 and 65 ng/ml, respectively. at this time, estimated glomerular filtration rate (egfr) was 111 ml/min/1.73 m(2). app ... | 2013 | 23053505 |
| bacillary angiomatosis presenting as a pyogenic granuloma of the hand in an otherwise apparently healthy patient. | bacillary angiomatosis is a rare opportunistic infection caused by the gram-negative bacteria bartonella. the infection is strongly related to human immunodeficiency virus (hiv) infection, and hence, the diagnosis is usually considered based on the fact that the patient is hiv positive. we report on a case of bacillary angiomatosis presenting as a pyogenic granuloma of the hand in an otherwise apparently healthy man. the report is aimed to increase the awareness of hand surgeons that this seriou ... | 2013 | 23038144 |
| possible transmission of human immunodeficiency virus-1 infection from an elite controller to a patient who progressed to acquired immunodeficiency syndrome: a case report. | most individuals infected with human immunodeficiency virus-1, in the absence of antiretroviral therapy, exhibit persistent virus replication and declining cd4+ cell numbers, and progress to acquired immunodeficiency syndrome within 10 years of infection. elite controllers are rare individuals with human immunodeficiency virus-1 infection who can maintain undetectable plasma virus levels and remain asymptomatic without antiretroviral therapy. it has been proposed that elite controllers benefit f ... | 2012 | 22967353 |
| a 23-year-old man with fever and malaise. | acute infection with human immunodeficiency virus (hiv) is infrequently diagnosed, owing in large part to vague or non-specific symptoms. among the most common of these symptoms are fever, fatigue, pharyngitis, lymphadenopathy, anorexia, arthralgia, myalgia, rash, and headache. some patients seek no medical attention for such symptoms, and others recall no symptoms whatsoever. physicians in all healthcare environments must maintain a high index of suspicion for hiv in the setting of these sympto ... | 2012 | 22866358 |
| surgical management of bilateral parotid lipomatosis in a patient with hiv. | the long-term use of highly active antiretroviral therapy (haart) in patients with human immunodeficiency virus (hiv) has led to sequelae including lipodystrophy syndrome (lds). we present the first published case of surgical management of bilateral parotid lipomatosis in a patient with hiv on long-term haart. | 2013 | 22848004 |
| isolated homonymous hemianopsia due to presumptive cerebral tubercular abscess as the initial manifestation of human immunodeficiency virus infection. | we report a case of isolated homonymous hemianopsia due to presumptive cerebral tubercular abscess as the initial manifestation of human immunodeficiency virus (hiv) infection. a 30-year-old man presented to our outpatient department with sudden loss of visibility in his left visual field. he had no other systemic symptoms. perimetry showed left-sided incongruous homonymous hemianopsia denser above the horizontal meridian. magnetic resonance imaging revealed irregular well-marginated lobulated l ... | 2012 | 22824606 |
| hepatocellular carcinoma in a noncirrhotic patient with hiv: a case report and review of the literature. | a 59-year-old man with human immunodeficiency virus (hiv) was referred for persistently elevated liver enzyme activities. his hiv was well controlled on antiretroviral therapy and his viral load was undetectable. he had no history of chronic liver disease and had minimal alcohol intake. he was asymptomatic and his physical exam was unremarkable without any stigmata of liver disease. beyond the elevations in alkaline phosphatase and gamma-glutamyl transferase, the rest of his laboratory work, inc ... | 2012 | 22760658 |