| Treatment of residual pockets with photodynamic therapy, diode laser, or deep scaling. A randomized, split-mouth controlled clinical trial. | The objective of this work was to compare the effects of antimicrobial photodynamic therapy (PDT), diode soft laser therapy (DSL), and thorough deep scaling and root planing (SRP) for treatment of residual pockets. Thirty-two subjects with a history of non-surgical treatment for chronic periodontitis were included. Residual pockets >4 mm and bleeding upon probing were debrided with an ultrasonic device and then subjected to either PDT, DSL, or SRP. Pocket probing depth (PPD), bleeding on probing ... | 2011 | 22105837 |
| bacteroidales ectosymbionts of gut flagellates shape the nitrogen-fixing community in dry-wood termites. | although it is well documented that the lack of nitrogen in the diet of wood-feeding termites is compensated by the nitrogen-fixing capacity of their gut microbiota, the bacteria responsible for this activity are largely unknown. here, we analyzed the diversity and expression of nitrogenase genes (homologs of nifh) in four species of dry-wood termites (kalotermitidae), which thrive on a particularly nitrogen-poor resource. although each species harbored a highly diverse suite of termite-specific ... | 2011 | 22189498 |
| [Historical and medical review of syphilis-afflicted army leaders, rulers and statesmen]. | Syphilis has changed the course of history. It is a sexually transmitted disease caused by spiral-shaped bacterium, Treponema pallidum. The disease has been known under many names during history, and has had a prominent role in history and literature for the last several hundred years. Since its recognition in 15th-century Europe as a new disease, syphilis has been the subject of great mystery and legends. Many believe that syphilis was brought to Europe by Columbus and his sailors, and, thereaf ... | 2011 | 21970074 |
| Balanoposthitis, dyspareunia, and treponema in the critically endangered Gilbert's potoroo (Potorous gilbertii). | The Gilbert's potoroo (Potorous gilbertii) is one of Australia's most critically endangered mammals with a current estimated population of 70 individuals. Both the wild and captive populations have a long history of balanoposthitis with associated crusting, ulceration, and preputial discharge. We sought to identify the microbial species found in the discharge, determine their significance in causing balanoposthitis, and correlate these findings with reproductive success and survivorship. Bacteri ... | 2011 | 22102677 |
| association of kir2ds4 and its variant kir1d with syphilis in a chinese han population. | syphilis is a sexually transmitted infection caused by the treponema pallidum subspecies pallidum spirochaete bacterium. the killer immunoglobulin-like receptor (kir) gene family encodes cell surface receptors that are found on natural killer (nk) cells and certain t-cell subsets. nk cells are fast-acting effector lymphocytes of innate immunity that respond to infection. the activity of nk cells depends on the dynamic balance of activating and inhibitory signals that are transmitted through resp ... | 2011 | 22128817 |
| clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in lobaye, central african republic. | abstract: background: yaws is a bacterial skin and bone infectious disease caused by treponema pallidum pertenue. it is endemic, particularly among pygmies in central african republic. to assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the lobaye region. findings and conclusion the rate of healing of lesions after 5 months was 95.9%. this relatively satisfactory level of therapeutic response implies tha ... | 2011 | 22171605 |
| colonisation of the oral cavity by periodontopathic bacteria in complete denture wearers. | gerodontology 2011; doi: 10.1111/j.1741-2358.2011.00506.x colonisation of the oral cavity by periodontopathic bacteria in complete denture wearers objective: the purpose of this study was to investigate colonisation by periodontopathic bacteria and the sites of colonisation in elderly upper and lower complete denture wearers. we also investigated the relationship between level of oral hygiene and colonisation by periodontopathic bacteria. materials and methods: forty edentulous and 37 dentate ... | 2011 | 21929616 |
| association of kir genotypes and haplotypes with syphilis in a chinese han population. | killer immunoglobulin-like receptors (kirs) can regulate the activation of nk and t cells in response to infection. syphilis is a sexually transmitted infection caused by the treponema pallidum subspecies pallidum spirochete bacterium. the objective of this study was to explore whether kir genotypes and haplotypes were associated with syphilis in a chinese han population. polymerase chain reaction with sequence-specific primers (pcr-ssp) was used to identify the kir genotypes in 190 syphilis pat ... | 2011 | 22126195 |
| molecular typing of treponema pallidum: a systematic review and meta-analysis. | syphilis is resurgent in many regions of the world. molecular typing is a robust tool for investigating strain diversity and epidemiology. this study aimed to review original research on molecular typing of treponema pallidum (t. pallidum) with three objectives: (1) to determine specimen types most suitable for molecular typing; (2) to determine t. pallidum subtype distribution across geographic areas; and (3) to summarize available information on subtypes associated with neurosyphilis and macro ... | 2011 | 22087340 |
| Identification and functional analysis of CT069 as a novel transcriptional regulator in Chlamydia. | Only a small number of transcription factors have been predicted in Chlamydia spp., which are obligate intracellular bacteria that include a number of important human pathogens. We used a bioinformatics strategy to identify novel transcriptional regulators from the Chlamydia trachomatis genome by predicting proteins with the general structure and characteristic functional domains of a bacterial transcription factor. With this approach, we identified CT069 as a candidate transcription factor with ... | 2011 | 21908669 |
| infectious proctitis: when to suspect it is not inflammatory bowel disease. | background: proctitis is a common problem and is most frequently associated with inflammatory bowel diseases. however, the incidence of infectious proctitis appears to be rising, especially in men who have sex with men. this may be due to the rise of people participating in receptive anal sex as well as the increase in sexually transmitted infections. the most frequently reported pathogens include neisseria gonorrhoeae, chlamydia trachomatis, treponema pallidum, and herp ... | 2011 | 21994137 |
| Impact of international laboratory partnerships on the performance of HIV/sexually transmitted infection testing in five resource-constrained countries. | To review a quality control and quality assurance (QC/QA) model established to ensure the validity and reliability of collection, storage and analysis of biological outcome data, and to promote good laboratory practices (GLPs) and sustained operational improvements in international clinical laboratories, we conducted a two-arm randomized community-level HIV behavioural intervention trial in five countries: China, India, Peru, Russia and Zimbabwe. The trial was based on diffusion theory utilizing ... | 2011 | 22096049 |
| Syphilis seroprevalence among patients attending a sexually transmitted disease clinic in West Bengal, India. | Syphilis is a sexually transmitted disease (STD) and is a major public health concern in India. The trend of syphilis infection was studied in attendees aged 15-49 years in an STD clinic in West Bengal from 2004 to 2008. Blood samples were collected from 250 consecutive patients per year (a total of 1,250 samples over 5 years); the patients attended the STD clinic for 12 weeks (October-December) each year, and the serostatus of syphilis was determined qualitatively with the Venereal Disease ... | 2011 | 22116330 |
| Comparative analysis of salivary bacterial microbiome diversity in edentulous infants and their mothers or primary care givers using pyrosequencing. | Bacterial contribution to oral disease has been studied in young children, but there is a lack of data addressing the developmental perspective in edentulous infants. Our primary objectives were to use pyrosequencing to phylogenetically characterize the salivary bacterial microbiome of edentulous infants and to make comparisons against their mothers. Saliva samples were collected from 5 edentulous infants (mean age?=?4.6±1.2 mo old) and their mothers or primary care givers (mean age?=?30.8±9.5 y ... | 2011 | 21853142 |
| molecular detection of human periodontal pathogens in oral swab specimens from dogs in japan. | periodontal diseases are known to be major diseases in humans, and are also common in dogs. the purpose of the present study was to analyze the distribution of periodontitis-related bacterial species using oral swab specimens collected from 26 pet dogs. the distribution of an animal gingival organism porphyromonas gulae, in addition to 10 human periodontitis-related bacterial species, including porphyromonas gingivalis, treponema denticola, tannerella forsythia, capnocytophaga ochracea, capnocyt ... | 2011 | 21916371 |
| rapid multiplexed immunoassay for simultaneous serodiagnosis of hiv-1 and coinfections. | diagnosis of opportunistic infections in hiv-infected individuals remains a major public health challenge, particularly in resource-limited settings. here, we describe a rapid diagnostic system that delivers a panel of serologic immunoassay results using a single drop of blood, serum, or plasma. the system consists of disposable cartridges and a simple reader instrument, based on an innovative implementation of planar waveguide imaging technology. the cartridge incorporates a microarray of recom ... | 2011 | 21865431 |
| molecular detection of in-vivo microbial contamination of metallic orthodontic brackets by checkerboard dna-dna hybridization. | knowing the microbiota that colonizes orthodontic appliances is important for planning strategies and implementing specific preventive measures during treatment. the purpose of this clinical trial was to evaluate in vivo the contamination of metallic orthodontic brackets with 40 dna probes for different bacterial species by using the checkerboard dna-dna hybridization (cddh) technique. | 2012 | 22196182 |
| evaluation of a pcr test for the detection of treponema pallidum in swabs and blood. | syphilis diagnosis is based on clinical observation, serological analysis and dark-field microscopy detection of t. pallidum subsp. pallidum, the etiological agent of syphilis, in skin ulcers. we performed a nested pcr assay specifically amplifying the tpp47 gene of t pallidum from swab and blood specimens. we studied a cohort of 294 patients with suspected syphilis and 35 healthy volunteers. eight-seven of the 294 patients had primary syphilis, 103 had secondary syphilis, 40 had latent syphilis ... | 2012 | 22219306 |
| screening for syphilis: validation of the reverse sequence screening. | syphilis, which is caused by treponema pallidum, is a chronic bacterial infection that remains a public health concern worldwide.… | 2012 | 22259212 |
| microbial profile of patients with periodontitis compared with healthy subjects. | objective: to define and compare the microbiologic profile of subgingival plaque in german patients with periodontitis (including aggressive and advanced chronic periodontitis) and healthy subjects and to determine significant association between isolates and clinical status. aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, and tannerella forsythia are major periodontal pathogens, though it is recognized that other species may also contribute to the pathogenesis of periodontal di ... | 2012 | 22257880 |
| protective efficacy of a treponema pallidum gpd dna vaccine vectored by chitosan nanoparticles and fused with interleukin-2. | in the present study, immunomodulatory responses of a dna vaccine constructed by fusing treponema pallidum (tp) glycerophosphodiester phosphodiesterase (gpd) to interleukin-2 (il-2) and using chitosan (cs) nanoparticles as vectors were investigated. new zealand white rabbits were immunized by intramuscular inoculation of control dnas, tp gpd dna vaccine, or gpd-il-2 fusion dna vaccine, which were vectored by cs nanoparticles. levels of the anti-gpd antibodies and levels of il-2 and interferon- ... | 2012 | 22260167 |
| full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial. | aim: the present investigation aimed to analyse clinical and microbiological effects of systemic administration of metronidazole and amoxicillin combined with the one-stage-full-mouth-disinfection protocol (osfmd) in generalized aggressive periodontitis patients (g-agp). materials and methods: thirty-nine systemically healthy patients with g-agp were consecutively included. the test group (n = 19) received amoxicillin-metronidazole combination (500 mg of each, three times a day for 7 days) and t ... | 2012 | 22220822 |
| [prevalences and risk factors associated with infection by human immunodeficiency virus, hepatitis b virus, syphilis and bacillary pulmonary tuberculosis in prisons in burkina faso]. | this purpose of this study was to determine prevalences and risk factors associated with infection by human immunodeficiency virus, hepatitis b virus, syphilis and bacillary pulmonary tuberculosis in prisons in burkina faso. from february 20 to march 20, 2009, 300 prisoners over 18 years of age held in ouagadougou were selected to take part in this descriptive and analytical cross-sectional study. sociodemographic data, confinement information (number, motive and prison time), medical history, s ... | 2011 | 22235618 |
| necrotizing periodontal diseases in hiv-infected brazilian patients: a clinical and microbiologic descriptive study. | objective: nowadays, necrotizing periodontal diseases have a low prevalence; however, a better understanding of the etiopathogenesis of these diseases is necessary for determining more adequate preventive and therapeutic strategies. method and materials: from a pool of 1,232 hiv-infected patients, 15 presented with necrotizing periodontal diseases, which were evaluated by full-mouth periodontal clinical measurements. subgingival biofilm samples were collected from necrotizing lesions of six of t ... | 2012 | 22259811 |
| congenital syphilis in switzerland: gone, forgotten, on the return. | acquired syphilis has re-emerged in many western european countries. in contrast to international guidelines, screening for syphilis in pregnancy is not generally recommended in switzerland. there has been an increase in the incidence of laboratory syphilis notifications in recent years, regardless of gender and age. | 2012 | 22252171 |
| periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid. | in periodontitis, an effective host-response is primarily related to neutrophils loaded with serine proteases, including elastase (ne) and protease 3 (pr3), the extracellular activity of which is tightly controlled by endogenous inhibitors. in vitro these inhibitors are degraded by gingipains, cysteine proteases produced by porphyromonas gingivalis. the purpose of this study was to determine the level of selected protease inhibitors in gingival crevicular fluid (gcf) in relation to periodontal i ... | 2012 | 22230465 |