| who and experts prioritize vaccines, diagnostics and innovative vector control tools for zika r&d. | | 0 | 27508289 |
| who supports cabo verde in managing zika virus. | | 0 | 27508290 |
| knowledge sharing during public health emergencies: from global call to effective implementation. | | 0 | 27034513 |
| public health round-up. | | 0 | 27034514 |
| facts and ideas from anywhere. | | 0 | 27034577 |
| zika virus in the americas: early epidemiological and genetic findings. | brazil has experienced an unprecedented epidemic of zika virus (zikv), with ~30,000 cases reported to date. zikv was first detected in brazil in may 2015, and cases of microcephaly potentially associated with zikv infection were identified in november 2015. we performed next-generation sequencing to generate seven brazilian zikv genomes sampled from four self-limited cases, one blood donor, one fatal adult case, and one newborn with microcephaly and congenital malformations. results of phylogene ... | 2016 | 27013429 |
| an overview of zika virus disease. | | 2016 | 27366289 |
| possible repurposing of seasonal influenza vaccine for prevention of zika virus infection. | the in silico analysis shows that the envelope glycoproteins e of zika viruses (zikv) isolated in asia, africa and south and central america encode highly conserved information determining their interacting profile and immunological properties. previously it was shown that the same information is encoded in the primary structure of the hemagglutinin subunit 1 (ha1) from pdmh1n1 influenza a virus. this similarity suggests possible repurposing of the seasonal influenza vaccine containing pdmh1n1 ... | 2016 | 27158449 |
| virological factors that increase the transmissibility of emerging human viruses. | the early detection of pathogens with epidemic potential is of major importance to public health. most emerging infections result in dead-end "spillover" events in which a pathogen is transmitted from an animal reservoir to a human but is unable to achieve the sustained human-to-human transmission necessary for a full-blown epidemic. it is therefore critical to determine why only some virus infections are efficiently transmitted among humans whereas others are not. we sought to determine which b ... | 2016 | 27001840 |
| zika virus and neurologic autoimmunity: the putative role of gangliosides. | an increasing number of severe neurological complications associated with zika virus (zikv), chiefly guillain-barré syndrome (gbs) and primary microcephaly, have led the world health organization to declare a global health emergency. molecular mimicry between glycolipids and surface molecules of infectious agents explain most of the cases of gbs preceded by infection, while a direct toxicity of zikv on neural cells has been raised as the main mechanism by which zikv induces microcephaly. ganglio ... | 2016 | 27001187 |
| the zika pandemic - a perfect storm? | | 2016 | 26991663 |
| zika: structuring the european research response. | studies are needed to assess #zika virus risks and to develop diagnostic tests http://ow.ly/zaozw. | 2016 | 27730165 |
| modelling population dynamics in realistic landscapes with linear elements: a mechanistic-statistical reaction-diffusion approach. | we propose and develop a general approach based on reaction-diffusion equations for modelling a species dynamics in a realistic two-dimensional (2d) landscape crossed by linear one-dimensional (1d) corridors, such as roads, hedgerows or rivers. our approach is based on a hybrid "2d/1d model", i.e, a system of 2d and 1d reaction-diffusion equations with homogeneous coefficients, in which each equation describes the population dynamics in a given 2d or 1d element of the landscape. using the exampl ... | 2016 | 26986201 |
| financing and collaboration on research and development for nodding syndrome. | nodding syndrome is a neurological disease with no known cure or treatment, impacting children aged 3-18 years old, mainly in east africa. children progressively develop varying degrees of cognitive impairment which may lead to severe wasting, a vegetative state and, eventually, death. despite its 50-year existence, little is known about its cause, risk factors and prognosis. it is a disease where markets will not provide solutions because the patients are both too few and too poor, making it es ... | 2016 | 26983551 |
| association between zika virus and microcephaly in french polynesia, 2013-15: a retrospective study. | the emergence of zika virus in the americas has coincided with increased reports of babies born with microcephaly. on feb 1, 2016, who declared the suspected link between zika virus and microcephaly to be a public health emergency of international concern. this association, however, has not been precisely quantified. | 2016 | 26993883 |
| on the seasonal occurrence and abundance of the zika virus vector mosquito aedes aegypti in the contiguous united states. | an ongoing zika virus pandemic in latin america and the caribbean has raised concerns that travel-related introduction of zika virus could initiate local transmission in the united states (u.s.) by its primary vector, the mosquito aedes aegypti. | 2016 | 27066299 |
| zika virus: more questions than answers. | | 2016 | 27077095 |
| zika virus infection and microcephaly. | a task force established by the brazil ministry of health investigated the possible association of microcephaly with zika virus infection during pregnancy and a registry for microcephaly cases among women suspected to have had zika virus infection during pregnancy. | 0 | 27004142 |
| zika virus outbreak: 'a perfect storm'. | | 2016 | 26956448 |
| first complete genome sequence of zika virus (flaviviridae, flavivirus) from an autochthonous transmission in brazil. | we report here the genome sequence of zika virus, strain zikasph2015, containing all structural and nonstructural proteins flanked by the 5' and 3' untranslated region. it was isolated in são paulo state, brazil, in 2015, from a patient who received a blood transfusion from an asymptomatic donor at the time of donation. | 2016 | 26941134 |
| differential susceptibilities of aedes aegypti and aedes albopictus from the americas to zika virus. | since the major outbreak in 2007 in the yap island, zika virus (zikv) causing dengue-like syndromes has affected multiple islands of the south pacific region. in may 2015, the virus was detected in brazil and then spread through south and central america. in december 2015, zikv was detected in french guiana and martinique. the aim of the study was to evaluate the vector competence of the mosquito spp. aedes aegypti and aedes albopictus from the caribbean (martinique, guadeloupe), north america ( ... | 2016 | 26938868 |
| the expanding spectrum of modes of transmission of zika virus: a global concern. | | 2016 | 26939897 |
| pandemics, ebola, and the family doctor. | | 0 | 26975910 |
| zika - a pandemic in progress? | the emerging threat of zika virus outbreak with associated neurological abnormalities needs to be assessed in perspective in terms of its ability to cause a pandemic. this article attempts to throw some light on the issue. | 0 | 27547117 |
| blood safety and zoonotic emerging pathogens: now it's the turn of zika virus! | | 2015 | 26674809 |
| data sharing in public health emergencies: a call to researchers. | | 0 | 26966322 |
| brazil's scientists scramble to solve the zika puzzle. | the world health organization has declared the recent leap in the number of microcephaly cases and their suspected association with zika virus a public health emergency of international concern. ana bispo tells andréia azevedo soares why brazil should have some scientific answers in coming months. | 0 | 26966326 |
| highly divergent dengue virus type 1 genotype sets a new distance record. | dengue viruses (denvs) are the leading cause of mosquito-borne viral disease of humans. they exist in both endemic and sylvatic ecotypes. in 2014, a viremic patient who had recently visited the rainforests of brunei returned to australia displaying symptoms consistent with denv infection. a unique denv strain was subsequently isolated from the patient, which we propose belongs to a new genotype within denv serotype 1 (denv-1). bayesian evolutionary phylogenetic analysis suggests that the putativ ... | 2016 | 26924208 |
| zika virus infection and stillbirths: a case of hydrops fetalis, hydranencephaly and fetal demise. | the rapid spread of zika virus in the americas and current outbreak of microcephaly in brazil has raised attention to the possible deleterious effects that the virus may have on fetuses. | 2016 | 26914330 |
| evaluating probabilistic dengue risk forecasts from a prototype early warning system for brazil. | recently, a prototype dengue early warning system was developed to produce probabilistic forecasts of dengue risk three months ahead of the 2014 world cup in brazil. here, we evaluate the categorical dengue forecasts across all microregions in brazil, using dengue cases reported in june 2014 to validate the model. we also compare the forecast model framework to a null model, based on seasonal averages of previously observed dengue incidence. when considering the ability of the two models to pred ... | 2016 | 26910315 |
| infectious diseases. beyond ebola. | | 0 | 26912880 |
| simultaneous outbreaks of dengue, chikungunya and zika virus infections: diagnosis challenge in a returning traveller with nonspecific febrile illness. | zika virus is an emerging flavivirus that is following the path of dengue and chikungunya. the three aedes-borne viruses cause simultaneous outbreaks with similar clinical manifestations which represents a diagnostic challenge in ill returning travellers. we report the first zika virus infection case imported to switzerland and present a diagnostic algorithm. | 2016 | 27006779 |
| zika virus infection: new threat in global health. | | 2016 | 26955231 |
| international health regulations, ebola, and emerging infectious diseases in latin america and the caribbean. | the world health organization's determination of the ebola virus disease outbreak as a public health event of international concern prompted nonaffected countries to implement measures to prevent, detect, and manage the introduction of the virus in their territories. the outbreak provided an opportunity to assess the operational implementation of the international health regulations' core capacities and health systems' preparedness to handle a potential or confirmed case of ebola virus disease. ... | 2015 | 26691130 |
| larvicidal potential of the halogenated sesquiterpene (+)-obtusol, isolated from the alga laurencia dendroidea j. agardh (ceramiales: rhodomelaceae), against the dengue vector mosquito aedes aegypti (linnaeus) (diptera: culicidae). | dengue is considered a serious public health problem in many tropical regions of the world including brazil. at the moment, there is no viable alternative to reduce dengue infections other than controlling the insect vector, aedes aegypti linnaeus. in the continuing search for new sources of chemicals targeted at vector control, natural products are a promising alternative to synthetic pesticides. in our work, we investigated the toxicity of a bioactive compound extracted from the red alga laure ... | 2016 | 26821032 |
| anticipating the international spread of zika virus from brazil. | | 2016 | 26777915 |
| frozen funding on firearm research: "doing nothing is no longer an acceptable solution". | | 2016 | 26823941 |
| cytokine kinetics of zika virus-infected patients from acute to reconvalescent phase. | zika virus is an emerging mosquito-borne flavivirus currently causing large epidemics in the pacific ocean region and brazil. clinically, zika fever resembles dengue fever, but is less severe. whereas the clinical syndrome and laboratory diagnostic procedures have been described, little attention was paid to the immunology of the disease and its possible use for clinical follow-up of patients. here, we investigate the role of cytokines in the pathogenesis of zika fever in travelers returning fro ... | 2015 | 26702627 |
| outbreak of exanthematous illness associated with zika, chikungunya, and dengue viruses, salvador, brazil. | | 0 | 26584464 |
| climate change and health in pacific island states. | | 0 | 26668431 |
| zika virus transmission from french polynesia to brazil. | | 0 | 26403318 |
| biocontrol evaluation of extracts and a major component, clusianone, from clusia fluminensis planch. & triana against aedes aegypti. | studies evaluated the effects of hexanic extracts from the fruits and flowers of clusia fluminensis and the main component of the flower extract, a purified benzophenone (clusianone), against aedes aegypti. the treatment of larvae with the crude fruit or flower extracts from c. fluminensis did not affect the survival ofae. aegypti (50 mg/l), however, the flower extracts significantly delayed development of ae. aegypti. in contrast, the clusianone (50 mg/l) isolate from the flower extract, repres ... | 2015 | 26200711 |
| co-infection with zika and dengue viruses in 2 patients, new caledonia, 2014. | | 0 | 25625687 |
| functional characterization of aquaporins and aquaglyceroporins of the yellow fever mosquito, aedes aegypti. | after taking vertebrate blood, female mosquitoes quickly shed excess water and ions while retaining and concentrating the mostly proteinaceous nutrients. aquaporins (aqps) are an evolutionary conserved family of membrane transporter proteins that regulate the flow of water and in some cases glycerol and other small molecules across cellular membranes. in a previous study, we found six putative aqp genes in the genome of the yellow fever mosquito, ae. aegypti, and demonstrated the involvement of ... | 2015 | 25589229 |
| assessment of climate-sensitive infectious diseases in the federated states of micronesia. | the health impacts of climate change are an issue of growing concern in the pacific region. prior to 2010, no formal, structured, evidence-based approach had been used to identify the most significant health risks posed by climate change in pacific island countries. during 2010 and 2011, the world health organization supported the federated states of micronesia (fsm) in performing a climate change and health vulnerability and adaptation assessment. this paper summarizes the priority climate-sens ... | 2014 | 25859151 |
| trouble in paradise. | | 2014 | 26839785 |
| in response. | | 0 | 25513658 |
| zika virus, french polynesia, south pacific, 2013. | | 0 | 25341051 |
| zika virus. | | 0 | 24983096 |
| crossing borders: one world, global health. | | 0 | 24627562 |
| the genetic basis of host preference and resting behavior in the major african malaria vector, anopheles arabiensis. | malaria transmission is dependent on the propensity of anopheles mosquitoes to bite humans (anthropophily) instead of other dead end hosts. recent increases in the usage of long lasting insecticide treated nets (llins) in africa have been associated with reductions in highly anthropophilic and endophilic vectors such as anopheles gambiae s.s., leaving species with a broader host range, such as anopheles arabiensis, as the most prominent remaining source of transmission in many settings. an. arab ... | 2016 | 27631375 |
| rerouting biomedical innovation: observations from a mapping of the alternative research and development (r&d) landscape. | in recent years, the world has witnessed the tragic outcomes of multiple global health crises. from ebola to high prices to antibiotic resistance, these events highlight the fundamental constraints of the current biomedical research and development (r&d) system in responding to patient needs globally.to mitigate this lack of responsiveness, over 100 self-identified "alternative" r&d initiatives, have emerged in the past 15 years. to begin to make sense of this panoply of initiatives working to o ... | 2016 | 27627882 |
| bacterial larvicide, bacillus thuringiensis israelensis strain am 65-52 water dispersible granule formulation impacts both dengue vector, aedes aegypti (l.) population density and disease transmission in cambodia. | a multi-phased study was conducted in cambodia from 2005-2011 to measure the impact of larviciding with the bacterial larvicide, bacillus thuringiensis israelensis (bti), a water dispersible granule (wg) formulation on the vector, aedes aegypti (l.) and the epidemiology. in our studies, all in-use containers were treated at 8 g/1000 l, including smaller containers and animal feeders which were found to contribute 23% of ae aegypti pupae. the treated waters were subjected to routine water exchang ... | 2016 | 27627758 |
| zika: an old virus with a new face. | zika virus is a mosquito-borne flavivirus that represents a public health emergency at the ongoing epidemic. this obscure virus was limited to sporadic cases in africa and asia, until the emergence of zika virus in brazil in 2015, when it rapidly spread throughout the americas. most zika virus infections are subclinical or characterized by mild febrile illness. however, neurological complications, including guillain-barré syndrome in adults, and congenital anomalies, including microcephaly in ba ... | 2016 | 27703544 |
| understanding ebola: the 2014 epidemic. | near the end of 2013, an outbreak of zaire ebolavirus (ebov) began in guinea, subsequently spreading to neighboring liberia and sierra leone. as this epidemic grew, important public health questions emerged about how and why this outbreak was so different from previous episodes. this review provides a synthetic synopsis of the 2014-15 outbreak, with the aim of understanding its unprecedented spread. we present a summary of the history of previous epidemics, describe the structure and genetics of ... | 2016 | 27624088 |
| population surveillance for microcephaly. | | 2016 | 27623958 |
| prevalence of microcephaly in europe: population based study. | to provide contemporary estimates of the prevalence of microcephaly in europe, determine if the diagnosis of microcephaly is consistent across europe, and evaluate whether changes in prevalence would be detected using the current european surveillance performed by eurocat (the european surveillance of congenital anomalies). | 2016 | 27623840 |
| with great power comes great responsibility-a personal philosophy for communicating science in society. | many think that communicating science is a necessary and rewarding activity. yet finding compelling, relevant, and timely points of linkage between challenging scientific concepts and the experiences and interests of the general public can be difficult. since science continues to influence more and more aspects of daily life and knowledge, there is a parallel need for communication about science in our society. here i discuss the "middle-ground hypothesis" using popular culture for science commu ... | 2016 | 27642632 |
| isolation of zika virus imported from tonga into australia. | the globally emergent zika virus (zikv) is a threat to australia, given the number of imported cases from epidemic regions and the presence of competent mosquito vectors. we report the isolation of zikv from a female traveler who recently returned from tonga to brisbane, queensland, australia in 2016. | 2016 | 27679739 |
| infectious diseases epidemic threats and mass gatherings: refocusing global attention on the continuing spread of the middle east respiratory syndrome coronavirus (mers-cov). | media and world health organization (who) attention on zika virus transmission at the 2016 rio olympic games and the 2015 ebola virus outbreak in west africa diverted the attention of global public health authorities from other lethal infectious diseases with epidemic potential. mass gatherings such as the annual hajj pilgrimage hosted by kingdom of saudi arabia attract huge crowds from all continents, creating high-risk conditions for the rapid global spread of infectious diseases. the highly l ... | 2016 | 27604081 |
| zika virus infection in mice causes panuveitis with shedding of virus in tears. | zika virus (zikv) is an emerging flavivirus that causes congenital abnormalities and guillain-barré syndrome. zikv infection also results in severe eye disease characterized by optic neuritis, chorioretinal atrophy, and blindness in newborns and conjunctivitis and uveitis in adults. we evaluated zikv infection of the eye by using recently developed mouse models of pathogenesis. zikv-inoculated mice developed conjunctivitis, panuveitis, and infection of the cornea, iris, optic nerve, and ganglion ... | 2016 | 27612415 |
| in this month's bulletin. | | 0 | 27708463 |
| mapping the global geographic potential of zika virus spread. | the americas are presently experiencing the most serious known outbreak of zika virus (zikv). here, we present a novel set of analyses using environmental characteristics, vector mosquito distributions, and socioeconomic risk factors to develop the first map to detail global zikv transmission risk in multiple dimensions based on ecological niche models. our model predictions were tested against independent evaluation data sets, and all models had predictive ability significantly better than rand ... | 0 | 27653360 |
| genome sequence of a candidate world health organization reference strain of zika virus for nucleic acid testing. | we report here the sequence of a candidate reference strain of zika virus (zikv) developed on behalf of the world health organization (who). the zikv reference strain is intended for use in nucleic acid amplification (nat)-based assays for the detection and quantification of zikv rna. | 2016 | 27587826 |
| autochthonous chikungunya fever in traveler returning to japan from cuba. | | 0 | 27533717 |
| inactivation and environmental stability of zika virus. | | 2016 | 27367466 |
| specificity of dengue ns1 antigen in differential diagnosis of dengue and zika virus infection. | | 2016 | 27347853 |
| use of transgenic aedes aegypti in brazil: risk perception and assessment. | the ox513a strain of aedes aegypti, which was developed by the british company oxitec, expresses a self-limiting transgene that prevents larvae from developing to adulthood. in april 2014, the brazilian national technical commission on biosafety completed a risk assessment of ox513a and concluded that the strain did not present new biological risks to humans or the environment and could be released in brazil. at that point, brazil became the first country to approve the unconstrained release of ... | 2016 | 27843167 |
| systematic development of an evidence-based website on preconception care. | in february 2015, the flemish minister of welfare, public health and family launched a website on preconception care: 'gezondzwangerworden.be'. the website was developed in response to the lack of comprehensive communication on preconception care and the inadequate intake of folic acid among flemish women. despite the international recommendation to take 400 μg folic acid on a daily basis one month before conception until 12 weeks of pregnancy, studies show a lack of compliance in women wanting ... | 2016 | 27586661 |
| moonshot science-risks and benefits. | ever since the successful apollo 11 moon landing in 1969, a "moonshot" has come to signify a bold effort to achieve a seemingly impossible task. the obama administration recently called for a moonshot to cure cancer, an initiative that has elicited mixed responses from researchers who welcome additional funding but worry about raising expectations. we suggest that a successful moonshot requires a sufficient understanding of the basic science underlying a problem in question so that efforts can b ... | 2016 | 27578761 |
| an ecological assessment of the pandemic threat of zika virus. | the current outbreak of zika virus poses a severe threat to human health. while the range of the virus has been cataloged growing slowly over the last 50 years, the recent explosive expansion in the americas indicates that the full potential distribution of zika remains uncertain. moreover, many studies rely on its similarity to dengue fever, a phylogenetically closely related disease of unknown ecological comparability. here we compile a comprehensive spatially-explicit occurrence dataset from ... | 2016 | 27564232 |
| techno-economic analysis of a transient plant-based platform for monoclonal antibody production. | plant-based biomanufacturing of therapeutic proteins is a relatively new platform with a small number of commercial-scale facilities, but offers advantages of linear scalability, reduced upstream complexity, reduced time to market, and potentially lower capital and operating costs. in this study we present a detailed process simulation model for a large-scale new "greenfield" biomanufacturing facility that uses transient agroinfiltration of nicotiana benthamiana plants grown hydroponically indoo ... | 2016 | 27559626 |
| lessons from ebola: sources of outbreak information and the associated impact on uc irvine and ohio university college students. | objectives. we examined the role of outbreak information sources through four domains: knowledge, attitudes, beliefs, and stigma related to the 2014 ebola virus disease (evd) outbreak. methods. we conducted an online survey of 797 undergraduates at the university of california, irvine (uci) and ohio university (ou) during the peak of the outbreak. we calculated individual scores for domains and analyzed associations to demographic variables and news sources. results. knowledge of evd was low and ... | 2016 | 27651977 |
| illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens. | ocular infections remain a major cause of blindness and morbidity worldwide. while prognosis is dependent on the timing and accuracy of diagnosis, the etiology remains elusive in ~50 % of presumed infectious uveitis cases. the objective of this study is to determine if unbiased metagenomic deep sequencing (mds) can accurately detect pathogens in intraocular fluid samples of patients with uveitis. | 2016 | 27562436 |
| antibody engineering & therapeutics 2016: the antibody society's annual meeting, december 11-15, 2016, san diego, ca. | antibody engineering & therapeutics, the largest meeting devoted to antibody science and technology and the annual meeting of the antibody society, will be held in san diego, ca on december 11-15, 2016. each of 14 sessions will include six presentations by leading industry and academic experts. in this meeting preview, the session chairs discuss the relevance of their topics to current and future antibody therapeutics development. session topics include bispecifics and designer polyclonal antibo ... | 2016 | 27557809 |
| zika virus infection: some facts. | | 2016 | 28042362 |
| a one health overview, facilitating advances in comparative medicine and translational research. | a1 one health advances and successes in comparative medicine and translational researchcheryl strouda2 dendritic cell-targeted gorilla adenoviral vector for cancer vaccination for canine melanomaigor dmitriev, elena kashentseva, jeffrey n. bryan, david t. curiela3 viroimmunotherapy for malignant melanoma in the companion dog modeljeffrey n. bryan, david curiel, igor dmitriev, elena kashentseva, hans rindt, carol reinero, carolyn j. henrya4 of mice and men (and dogs!): development of a commercial ... | 0 | 27558513 |
| decreasing unintended pregnancy: opportunities created by the affordable care act. | | 0 | 27455194 |
| the rise and fall of infectious disease in a warmer world. | now-outdated estimates proposed that climate change should have increased the number of people at risk of malaria, yet malaria and several other infectious diseases have declined. although some diseases have increased as the climate has warmed, evidence for widespread climate-driven disease expansion has not materialized, despite increased research attention. biological responses to warming depend on the non-linear relationships between physiological performance and temperature, called the therm ... | 2016 | 27610227 |
| zika virus productively infects primary human placenta-specific macrophages. | the strong association of zika virus infection with congenital defects has led to questions of how a flavivirus is capable of crossing the placental barrier to reach the fetal brain. here, we demonstrate permissive zika virus infection of primary human placental macrophages, commonly referred to as hofbauer cells, and placental villous fibroblasts. we also demonstrate zika virus infection of hofbauer cells within the context of the tissue ex vivo using term placental villous explants. in additio ... | 0 | 27595140 |
| complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of zika virus: mr-766, p6-740, and prvabc-59. | here, we report the 10,807-nucleotide-long consensus rna genome sequences of three spatiotemporally distinct and genetically divergent zika virus strains, with the functionality of their genomic sequences substantiated by reverse genetics: mr-766 (african lineage, uganda, 1947), p6-740 (asian lineage, malaysia, 1966), and prvabc-59 (asian lineage-derived american strain, puerto rico, 2015). | 2016 | 27540058 |
| make data sharing routine to prepare for public health emergencies. | jean-paul chretien and colleagues argue that recent ebola and zika virus outbreaks highlight the importance of data sharing in scientific research. | 2016 | 27529422 |
| zika virus: a call to action for physicians in the era of climate change. | in february 2016, the world health organization declared the mosquito-borne zika virus to be a "public health emergency of international concern" as the disease linked to thousands of birth defects in brazil spreads rapidly. the distribution of the aedes mosquitos has drastically increased over the past few decades, which have been the hottest decades on earth in more than 1000 years based on climate proxy measures. although a combination of factors explains the current zika virus outbreak, it's ... | 2016 | 27617189 |
| the importance of male body size on sperm uptake and usage, and female fecundity in aedes aegypti and aedes albopictus. | adult mosquito density is a critical factor in the transmission of arboviruses by container aedes spp. mosquitoes. female fecundity drives population growth, and therefore contributes to adult mosquito density. previous studies have focused on female body size as the major determinant of fecundity, paying little attention to male condition. in this study, we examined the effects of male body size on the abundance of sperm in spermatheca, depletion of sperm over time, and female fecundity. | 2016 | 27519588 |
| travel-associated and autochthonous zika virus infection in mainland france, 1 january to 15 july 2016. | during summer 2016, all the conditions for local mosquito-borne transmission of zika virus (zikv) are met in mainland france: a competent vector, aedes albopictus, a large number of travellers returning from zikv-affected areas, and an immunologically naive population. from 1 january to 15 july 2016, 625 persons with evidence of recent zikv infection were reported in mainland france. we describe the surveillance system in place and control measures implemented to reduce the risk of infection. | 0 | 27542120 |
| on the ground in western africa: from the outbreak to the elapse of ebola. | | 0 | 27502186 |
| perinatal neuroprotection update. | antepartum, intrapartum, and neonatal events can result in a spectrum of long-term neurological sequelae, including cerebral palsy, cognitive delay, schizophrenia, and autism spectrum disorders [1]. advances in obstetrical and neonatal care have led to survival at earlier gestational ages and consequently increasing numbers of periviable infants who are at significant risk for long-term neurological deficits. therefore, efforts to decrease and prevent cerebral insults attempt not only to decreas ... | 2016 | 27606053 |
| congenital zika syndrome with arthrogryposis: retrospective case series study. | to describe the clinical, radiological, and electromyographic features in a series of children with joint contractures (arthrogryposis) associated with congenital infection presumably caused by zika virus. | 2016 | 27509902 |
| the critical role of early dengue surveillance and limitations of clinical reporting - implications for non-endemic countries. | the increasing dengue burden and epidemic severity worldwide have highlighted the need to improve surveillance. in non-endemic areas such as taiwan, where outbreaks start mostly with imported cases from southeast asia, a closer examination of surveillance dynamics to detect cases early is necessary. to evaluate problems with dengue surveillance and investigate the involvement of different factors at various epidemic stages, we investigated 632 laboratory-confirmed indigenous dengue cases in kaoh ... | 2016 | 27501302 |
| estimating geographical variation in the risk of zoonotic plasmodium knowlesi infection in countries eliminating malaria. | infection by the simian malaria parasite, plasmodium knowlesi, can lead to severe and fatal disease in humans, and is the most common cause of malaria in parts of malaysia. despite being a serious public health concern, the geographical distribution of p. knowlesi malaria risk is poorly understood because the parasite is often misidentified as one of the human malarias. human cases have been confirmed in at least nine southeast asian countries, many of which are making progress towards eliminati ... | 2016 | 27494405 |
| complete genome sequence of zika virus isolated in mexico, 2016. | zika virus belongs to the genus flavivirus, and its spread remains an international public health emergency. in this report, we describe the obtainment and molecular characterization of a complete viral genome through the direct metagenomic analysis from saliva from an autochthonous transmission case in mexico. | 2016 | 27491989 |
| zika virus infection presenting with postauricular lymphadenopathy. | | 2016 | 26884455 |
| the emerging battlefront: infectious diseases. | | 0 | 27688273 |
| early identification of motor delay: family-centred screening tool. | to describe the harris infant neuromotor test (hint), an infant neuromotor test using canadian norms published in 2010 that could be used to screen for motor delay during the first year of life. | 0 | 27521388 |
| febrile or exanthematous illness associated with zika, dengue, and chikungunya viruses, panama. | | 2016 | 27139219 |
| zika virus disease in traveler returning from vietnam to israel. | | 2016 | 27331627 |
| time lags between exanthematous illness attributed to zika virus, guillain-barré syndrome, and microcephaly, salvador, brazil. | zika virus infection emerged as a public health emergency after increasing evidence for its association with neurologic disorders and congenital malformations. in salvador, brazil, outbreaks of acute exanthematous illness (aei) attributed to zika virus, guillain-barré syndrome (gbs), and microcephaly occurred in 2015. we investigated temporal correlations and time lags between these outbreaks to identify a common link between them by using epidemic curves and time series cross-correlations. numb ... | 2016 | 27144515 |
| a role for science in responding to health crises. | the department of homeland security's (dhs) science and technology (s&t) directorate plays a role in public health that extends beyond biodefense. these responsibilities were exercised as part of the 2014-16 ebola outbreak, leading to productive and beneficial contributions to the international public health response and improved operations in the united states. however, we and others have identified numerous areas for improvement. based on our successes and lessons learned, we propose a number ... | 0 | 27482881 |
| public health round-up. | | 0 | 27516631 |
| drug and device news. | approvals, new indications, regulatory activities, and more. | 0 | 27504062 |