| dermatophytoses in children: study of 137 cases. | dermatophytoses are common fungal infections caused by dermatophytes but there are few data about this condition in the childhood. 137 children below the age of 12 and clinically diagnosed as tineas were investigated prospectively at instituto de puericultura e pediatria, rio de janeiro, from 1994 to 1999. hair, skin/nails scraping and pus swabs were collected from lesions and processed for fungus. male children from 2 to 12 years were mostly affected; tinea capitis (78 cases) mainly caused by m ... | 2001 | 11340481 |
| tinea capitis: study of asymptomatic carriers and sick adolescents, adults and elderly who live with children with the disease. | tinea capitis is a dermatophyte infection that occurs mainly in childhood; there are few reports, in brazil, in adolescents and adults. the detection of asymptomatic carriers is of great importance in the disease control. from february 1998 to february 1999, a study was performed at the outpatient dermatologic unit of instituto de puericultura e pediatria martagão gesteira (universidade federal do rio de janeiro, brasil) to verify the frequency of asymptomatic carriers and tinea capitis between ... | 2001 | 11340482 |
| a specific pcr assay for the dermatophyte fungus microsporum canis. | a dna fragment of approximately 1.2 kb, generated from the common dermatophyte microsporum canis by arbitrarily primed polymerase chain reaction (pcr) using random primer opu13, was cloned and sequenced. based on the resulting sequencing data, a forward primer (mc1f) and a reverse primer (mc1r) have been designed and assessed by pcr for their usefulness in the improved identification of m. canis. the results obtained suggest that these primers are specific for m. canis, as a band of 900 bp was a ... | 2001 | 11346271 |
| a case of feline otitis externa due to microsporum canis. | we describe a case of a 3-month-old persian male cat with a persistent waxy, ceruminous, otic discharge in both external auditory canals. after microbiological culture, only microsporum canis was isolated with no concurrent fungal or bacterial flora. fungal otitis due to dermatophytes was diagnosed and specific treatment with griseofulvin was administered. after 4 weeks of treatment, no m. canis colonies were isolated and clinical recovery had occurred. in view of this case, dermatophytosis shou ... | 2001 | 11346273 |
| the aetiological agents of tinea capitis in zaragoza (spain). | between 1977 and 1997, 190 cases of tinea capitis were observed. the age groups most commonly infected were 1-10 years old. the following dermatophytes were isolated: microsporum canis (119), trichophyton mentagrophytes (57), trichophyton tonsurans (seven), trichophyton verrucosum (three), trichophyton violaceum (one), trichophyton schoenleinii (one), trichophyton soudanense (one) and microsporum audouinii (one). | 2001 | 11398641 |
| antifungal activity of modified hederagenin glycosides from the leaves of kalopanax pictum var. chinense. | monodesmosides which were obtained from the partial degradation of hederagenin bisdesmosides exhibited significant antifungal effect against microsporum canis, coccidioides immitis, trichophyton mentagrophytes, cryptococcus neoformans, and candida albicans at the minimal inhibitory concentrations of 6.25-25 microg/ml. the hederagenin glycosides were isolated from the leaves of kalopanax pictum var. chinense. | 2001 | 11411568 |
| oral terbinafine for tinea capitis due to microsporum canis in children. | | 2001 | 11411922 |
| case report. onychomycosis due to microsporum canis. | a case of distal subungual onychomycosis of the big toe due to microsporum canis is reported in a 69-year-old male asthma patient who had been treated with systemic corticosteroids for the last 3 years. the nail infection was contracted from a cat who was a healthy carrier. the patient was treated successfully with intermittent itraconazole therapy. | 2001 | 11413924 |
| effectiveness of terbinafine in the eradication of microsporum canis from laboratory cats. | in this study, the coats of 20 cats with no dermatophytosis lesions were sampled for colonization by microsporum canis, which was isolated in 45% of cases. all cats were treated with oral terbinafine for 3 weeks. the drug was administered orally at a daily dosage 8.25 mg kg-1. mycologic status was assessed at the end of the treatment; and after follow-up at 2 days, and 4 and 9 weeks. the final evaluation revealed a complete mycologic cure of all cats by obtaining negative cultures, thereby demon ... | 2001 | 11413930 |
| evaluation of the dermatophyte test medium rapidvet-d. | the performance of the dermatophyte test medium (dtm) rapidvet-d was assessed using hair samples collected from experimentally infected guinea pigs. three dermatophyte species were included in the study: microsporum canis, trichophyton mentagrophytes and trichophyton equinum. dtm substrates were inoculated with infected hairs and scales, incubated at 18, 21, 24, 27 or 37 degrees c and examined daily for 15 days. the rapidity of colour change was clearly related to the incubation temperature and ... | 2001 | 11420927 |
| purification and characterization of a 43.5 kda keratinolytic metalloprotease from microsporum canis. | a keratinolytic protease secreted by a feline clinical isolate of microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by affinity chromatography on bacitracin-agarose and by hydrophobic chromatography on octyl-agarose. the enzyme had an apparent molecular mass of 43.5 kda and the pi was 7.7. it had a significant activity against keratin azure, elastin-congo red and denatured type i collagen (azocoll). using the latt ... | 2001 | 11446530 |
| hair and scalp mycobiota in school children in nablus area. | hair and scalp mycobiota of 1389 clinically normal children aged 6-12 years attending 12 schools in the nablus district, palestinian authority, was assessed on three occasions over 8-month period (october 1998-may 1999) using the hair brush technique. one hundred and one fungal species belonging to 33 genera were recovered: 6 dermatophytes, 16 dermatophyte-like keratinophilic fungi, and 79 other keratinophilic fungal species. species varied considerably in their frequency of occurrence and abund ... | 2001 | 11469760 |
| two cases of dermatophytic pseudomycetoma in the dog: an immunohistochemical study. | two cases of canine dermatophytic pseudomycetoma resulting in subcutaneous nodules resembling those previously reported in persian cats are described. culture performed from one nodule yielded dark yellow colonies consistent with microsporum canis. immunohistochemistry, using rabbit anti-m. canis, demonstrated specific binding to fungal elements in paraffin sections. the specificity of the antiserum was further tested by an agar gel immunodiffusion assay using a soluble extract from a feline iso ... | 2001 | 11493404 |
| expression of ubiquitin gene in microsporum canis and trichophyton mentagrophytes cultured with fluconazole. | the expression of the ubiquitin (ub) gene in dermatophytes was examined for its relation to resistance against the antifungal drug fluconazole. the nucleotide sequences and the deduced amino acid sequences of the ub gene in microsporum canis were proven to be 99% similar to those of the ub gene in trichophyton mentagrophytes. expression of mrna of ub in m. canis and t. mentagrophytes was enhanced when the fungi were cultured with fluconazole. the antifungal activity of fluconazole against these ... | 2001 | 11502529 |
| application of pcr to distinguish common species of dermatophytes. | this report describes the application of pcr fingerprinting for the identification of species and varieties of common dermatophytes and related fungi utilizing as a single primer the simple repetitive oligonucleotide (gaca)(4). the primer was able to amplify all the strains, producing species-specific profiles for microsporum canis, microsporum gypseum, trichophyton rubrum, trichophyton ajelloi, and epidermophyton floccosum. intraspecific variability was not observed for these species. instead, ... | 2001 | 11526185 |
| cutaneous xanthomas with concurrent demodicosis and dermatophytosis in a cat. | multiple cutaneous xanthomas, associated with fasting hyperlipidaemia, are described in a 9-month-old domestic long-haired cat. a severely pruritic, papular, and crusting dermatitis affecting the head and neck, initially diagnosed as lesions of the eosinophilic granuloma complex, progressively developed on the head and pinnae. pruritus was controlled with administration of prednisolone and chlorambucil. repeat histological examination confirmed the diagnosis of cutaneous xanthoma and concurrent ... | 2001 | 11549045 |
| terbinafine hydrochloride treatment of microsporum canis experimentally-induced ringworm in cats. | cats represent the most important source of microsporum canis infection to people. terbinafine hydrochloride is commonly used in the treatment of microsporosis. its fungicidal action permits short period of treatment. it was our objective to evaluate the effectiveness of this drug in treatment of microsporosis in cats. we treated nine experimentally m. canis infected cats with terbinafine at a dose of 10-20mg/kg sid (low-dose group, ldg), nine cats with 30-40mg/kg sid (high-dose group, hdg), and ... | 2001 | 11557156 |
| doubled dose of oral terbinafine is required for microsporum canis tinea capitis. | fourteen children, ages 1-15 years, with microsporum canis tinea capitis were given oral terbinafine for 4 weeks at the recommended daily dose according to their weight: 10-20 kg, 62.5 mg; 20-40 kg, 125 mg; > 40 kg, 250 mg. because none of the patients had clinically responded to treatment by week 4 the dose of terbinafine was doubled (up to 250 mg) for an additional 4-8 weeks in six patients, and continued at the original dose in six patients. two patients dropped out of the study. on final eva ... | 2001 | 11576412 |
| tinea capitis in europe: new perspective on an old problem. | a survey of tinea capitis conducted under the auspices of the european confederation of medical mycology showed that laboratories contributing to a voluntary scheme for reporting have recently been seeing a different pattern of scalp ringworm. the survey was conducted among 92 medical mycology laboratories across 19 european countries by postal questionnaire comparing the years 1987 with 1997. the survey shows an overall increase in the numbers of cases caused by anthropophilic infections, which ... | 2001 | 11683286 |
| [an epidemiological study for fungus isolation during the twenty-five year periods from 1976 to 2000 in kitasato university hospital]. | we investigated an epidemiological study for fungus isolation in our hospital from 1976 to 2000. for 25 years, the total sample number of fungus examination were 64,296, and after 1988, the total sample number increased suddenly. as a whole, the positive ratio was constantly about 40%. when our hospital opened, the obstetrical and gynecological samples showed 38.8% for fungus examination, but recently, samples of the respiratory organ has increased. ratio of isolation for yeast, candida albicans ... | 2001 | 11712361 |
| a study of the efficacy of topical and systemic therapy for the treatment of feline microsporum canis infection. | microsporum canis infection was induced in 21 healthy spf-derived cats. once infection was established (4 weeks after inoculation) the cats were divided into three equal groups housed in separate rooms and monitored for 16 weeks. during this time, group a cats received oral griseofulvin at approximately 50 mg/kg daily and were shampooed twice weekly with a product containing chlorhexidine and miconazole. group b cats were treated with griseofulvin alone, and group c cats served as untreated cont ... | 2000 | 11716608 |
| pseudomycetoma caused by microsporum canis in a persian cat: lack of response to oral terbinafine. | an eight-year-old neutered female persian cat with a four-year history of relapsing skin disease, characterised by ulcerated nodules with a yellow granular discharge, was examined. a diagnosis of granulomatous dermatitis and panniculitis (pseudomycetoma) caused by microsporum canis was made on the basis of history, clinical signs, histopathological examination of skin biopsy specimens and culture of macerated tissue. because previous therapy, comprising repeated surgical excision and the adminis ... | 2001 | 11721986 |
| determination of terbinafine hydrochloride in cat hair by two chromatographic methods. | terbinafine hydrochloride (terbhcl) concentration on the site of infection with microsporum canis is a very important indicator of drug effectiveness. several chromatographic methods exist that can be used for the determination of terbhcl concentration in biological samples. a high performance liquid chromatographic (hplc) method and a gas chromatographic (gc) method have been compared and critically evaluated for the determination of a terbhcl levels in cat hair. the sensitivity and the lineari ... | 2001 | 11748682 |
| tinea capitis in adults during 1981-95 in northern greece. | the mycological laboratory of our hospital examined 31,073 patients between 1981 and 1995. sex, age, the residence of patients, the clinical type of tinea and contacts with other persons and animals were investigated. all the patients were also examined under wood's light. tinea capitis was diagnosed in 35 adults. trichophyton violaceum was the commonest aetiological agent (54.5%), especially in elderly women. the other anthropophilic fungi were t. rubrum (8.5%), t. schoenleinii (5.7%) and t. to ... | 2001 | 11766106 |
| tinea cruris due to combined infections of trichophyton mentagrophytes and microsporum canis. a case report. | | 2001 | 11800157 |
| further evaluation of rwandan medicinal plant extracts for their antimicrobial and antiviral activities. | a total of 45 rwandan plant extracts, belonging to 37 different plant species out of 21 families, were investigated for their antibacterial, antifungal, and antiviral properties. the plants were selected on the base of their ethnomedicinal use against infections and autoimmune diseases. from all the plant extracts tested, only clematis hirsuta (leaves) showed a pronounced antifungal activity against candida albicans and the dermatophytes trichophyton rubrum, epidermophyton floccosum, and microsp ... | 2002 | 11801376 |
| phenotypic characterization of microsporum canis isolated from cats and dogs. | to characterize strains of microsporum canis that infect dogs and cats in são paulo city, 30 isolates of this dermatophyte were tested for their ability to assimilate carbon and nitrogen sources, for proteinase and phospholipase secretion, for susceptibility to yeast killer toxins, and for susceptibility to the antifungals fluconazole, ketoconazole, itraconazole, 5-fluorocytosine and amphotericin b, in e test. all samples assimilated the nitrogen sources asparagine, ammonium sulphate, urea and s ... | 2001 | 11820261 |
| dermatophytoses in prague, czech republic, between 1987 and 1998. | over a 12-year period, from 1987 to 1998, the spectrum of aetiological agents isolated from 11208 patients (6265 females and 4943 males) suspected of having dermatomycosis was analysed in the mycological laboratory of the department of dermatology, charles university, prague. the most frequently examined locations were toenails (34.9%), feet (15.6%), fingernails (12.8%), toe webs (11%), trunk (10%) and hands (8.7%). dermatophytes were isolated from 5605 (30.2%) of all 18528 samples examined. amo ... | 2001 | 11820263 |
| synthesis of some 4-(alkylidene/arylidene)amino-2,4-dihydro-5- (2-thienyl)-3h-1,2,4-triazole-3-thiones tested for antimicrobial activity. | a series of 4-(alkylidene/arylidene)amino-2,4-dihydro-5- (2-thienyl)-3h-1,2,4-triazole-3-thiones (2a-h) were synthesized. the structural elucidation of all the compounds was made on the basis of analytical and spectral data (ir, 1h-nmr and eims). all synthesized compounds were evaluated for in vitro antimicrobial activity against various bacteria and fungi. some of the compounds demonstrated antimicrobial activity against staphylococcus aureus atcc 6538, staphylococcus epidermidis atcc 12228, tr ... | 2001 | 11822231 |
| tinea capitis in infants less than 1 year of age. | tinea capitis is the most frequent manifestation of dermatophyte infection in children, but because it is rare in the first months of life it is often misdiagnosed. here we report 15 cases of tinea capitis observed in italy in infants less than 1 year of age. there were 10 boys and 5 girls (mean age 6 months). diagnosis was confirmed by mycologic examination. microsporum canis was isolated in nine cases and trichophyton mentagrophytes in three. these 12 infants were italian and animals were the ... | 2001 | 11841628 |
| itraconazole is effective in the treatment of tinea capitis caused by microsporum canis. | tinea capitis is a relatively common superficial fungal infection in children which requires oral antifungal therapy. in a prospective, open study over 24 weeks, itraconazole 5 mg/kg/day, given as capsules or as an oral suspension for a period of 2-12 weeks, was used to treat children 1-12 years of age who had m. canis tinea capitis. children with mycologic evidence of m. canis tinea capitis were entered into the study and asked to return at week 2 and then every 2 weeks thereafter until cured, ... | 2001 | 11841643 |
| efficacy of itraconazole as a combined continuous/pulse therapy in feline dermatophytosis: preliminary results in nine cases. | this study evaluated the efficacy of itraconazole as a combined continuous/pulse therapy for feline dermatophytosis. nine cats with dermatophytosis caused by microsporum canis were treated with itraconazole at 10 mg kg(-1) orally once daily for 28 days and then on an alternate week regimen (1 week off, 1 week on) at the same dosage. cats were re-evaluated by physical examination and fungal culture at days 28, 42, 56 and 70 if necessary. treatment was stopped when two consecutive negative fungal ... | 2001 | 11844225 |
| case report. tinea corporis due to microsporum canis in a professional cyclist. | we report the case of a 20-year-old man, a professional cyclist, with multiple scaling plaques on his limbs that had been present for 40 days. our case of tinea corporis presented some peculiarities related to the aetiological agent microsporum canis and also its mode of transmission. | 2002 | 11856439 |
| topical treatment of tinea capitis in a neonate. | tinea capitis is the most common fungal skin infection in children. given that this infection invades the hair shaft and the pilosebaceous unit, systemic antifungal therapy is the gold standard of treatment. despite the neonate's increased susceptibility to infections, tinea capitis is rare in this population. we present the case of a 16-day-old infant with tinea capitis caused by microsporum canis and effectively treated with topical bifonazole 1%. | 2002 | 11868981 |
| [epidemiology and etiology of dermatophytosis in goiânia, go, brazil]. | dermatophytes are a group of closely related fungi that have the capacity to invade keratinized tissue (skin, hair, and nails) of humans and animals to produce infections called dermatophytosis. in order to review the etiology and epidemiology of dermatophytosis in goiânia, go, 1955 specimens with diagnostic suspicion of dermatophytic lesions, were collected from january to december, 1999, from the mycology laboratory in the institute of tropical pathology and public health, federal university o ... | 2002 | 11873256 |
| evaluation of topically applied enilconazole for the treatment of dermatophytosis in a persian cattery. | many persian catteries have long-standing dermatophyte infections and are particularly difficult to treat. enilconazole is a topical antifungal agent that has demonstrated good efficacy in recent studies. twenty-two persian cats naturally infected with microsporum canis in a breeding cattery were treated with topical 0.2% enilconazole and monitored for 180 days. the treatments were repeated every 3 days for a total of eight applications. all the cats improved clinically and became culture negati ... | 2002 | 11896967 |
| synthesis of variously 9,9-dialkylated octahydropyrimido [3,4-a]-s-triazines with potential antifungal activity. | 9,9-dialkyloctahydropyrimido[3,4-a]-s-triazines were synthesized by iminodimethylation reaction between a 5,5-dialkyl-6-aminopyrimidine-2.4(3h,5h)-dione, a substituted aniline and two moles of formaldehyde. the synthesis of.5,5-dialkyl-6-aminopy-rimidinedione consisted of the condensation of urea with ethyl 2,2-dialkylcyanoacetates. 18 octahydropyrimido[3,4-a]-s-triazines were synthesized and compounds resulting from a supplementary aminomethylation were also obtained. most of these compounds we ... | 2002 | 11902652 |
| efficacy of oral terbinafine in feline dermatophytosis due to microsporum canis. | microsporum canis is the dermatophyte most commonly responsible for ringworm in cats. the purpose of this paper was to evaluate the in vivo efficacy of oral terbinafine (lamisil; sandoz) in the treatment of feline ringworm caused by m canis, and to consider this drug as an alternative to griseofulvin or imidazoles. fifteen cats infected with m canis were treated orally once daily with 30 mg/kg of terbinafine over a 2-week period. all treated animals were checked for dermatophytes on the last day ... | 1999 | 11919014 |
| [fungistatic activity of a sesquiterpene lactone (tomentosin) isolated from fresh inula viscosa (asteraceae) flowers from the puglia region]. | a sesquiterpene lactone, tomentosin, has been isolated and identified form inula viscosá ait (asteraceae) flowers. the molecule, at 1 mg/ml concentration, showed to be active in vitro against microsporum canis, microsporum gypseum and trichophyton mentagrophytes. | 2001 | 11921538 |
| trichophyton violaceum is the dominant cause of tinea capitis in children in tripoli, libya: results of a two year survey. | the causative agents of tinea capitis in libyan nationals attending the out patient dermatology clinic of the tripoli medical centre over the period december 1997 to december 1999 were investigated. samples (hair and scalp scrapings) were taken from 940 patients who presented with suspected tinea capitis. the etiological agents were identified in 584 cases. trichophyton violaceum was found to be the most prevalent organism isolated being responsible for 64.4% (376/584) of culture positive cases, ... | 2002 | 11998877 |
| dermatophytes and other fungi associated with skin mycoses in tripoli, libya. | this study sought to determine the prevalence of skin infections and their causative agents in the libyan population. samples were collected from 2224 patients attending the dermatology clinics of the tripoli medical centre (tmc) between august 1997 and december 1999 and were submitted to a mycology laboratory for analysis. diagnosis was confirmed by microscopic examination in 1180 cases (53.1%) and the causative agent was isolated and cultured in 1160 cases (52.2%). dermatophytes, malassezia fu ... | 2002 | 12000510 |
| a study of dermatophytoses in sana'a, yemen republic. | the present study describes the extent and causative agents of dermatophytoses in sana'a, the capital of yemen republic. out of 1100 patients with various skin diseases, 16.6% were affected with dermatophytoses. among them, 70% were male and the age group 11-20 years was most susceptible to tinea infections. tinea corporis was the most common disease, followed by tinea capitis. one hundred and seventy isolates of dermatophytes related to 9 species were identified. microsporum canis was the most ... | 2002 | 12000511 |
| case report. rosacea-like tinea incognito. | we report a case of dermatophytosis of the face due to microsporum canis that was exacerbated and altered clinically by a long-term application of topical corticosteroids. we considered this case a rosacea-like tinea incognito of the beard area. | 2002 | 12000520 |
| drug efficacy of terbinafine hydrochloride (lamisil) during oral treatment of cats, experimentally infected with microsporum canis. | cats represent a primary source of microsporum canis infections in humans. terbinafine hydrochloride (lamisil) is commonly used in the treatment of microsporosis in humans as its fungicidal action permits short periods of treatment. the aim of the present study was to estimate the efficacy of the drug in cats. nine cats were experimentally infected with m. canis and treated with terbinafine hydrochloride at a dose of 10-20 mg/kg (once daily, sid; low-dose group, ldg). another nine cats were simi ... | 2002 | 12019941 |
| proximal white subungual onychomycosis caused by microsporum canis in systemic lupus erythematosus. | we report the case of a mexican lupus patient who developed proximal white subungual onychomycosis on multiple toenails. microsporum canis was the causative agent. both nail invasion by m. canis and proximal white subungual onychomycosis are rare conditions indicative of an underlying immunodeficiency. | 2002 | 12036214 |
| production of extracellular enzymes by microsporum canis and their role in its virulence. | microsporum canis is the most prevalent dermatophyte of domestic animals. several enzymes produced by dermatophytes, particularly keratinases, are considered to play a role in the virulence of this fungus. to investigate the possible relationship between the clinical status of m. canis infection and enzymatic activity of isolates, we studied the relationship between keratinase, elastase, lipase and dnase levels produced in vitro by different isolates and virulence as expressed in a guinea pig mo ... | 2001 | 12054058 |
| in vitro susceptibility of microsporum canis and other dermatophyte isolates from veterinary infections during therapy with terbinafine or griseofulvin. | we investigated the in vitro activity of terbinafine against fresh veterinary isolates of microsporum canis and the potential of this organism to develop resistance in vivo during oral therapy. dermatophyte cultures (n = 300) were obtained from naturally infected cats and dogs undergoing oral therapy with terbinafine or griseofulvin. m. canis comprised 92% of isolates; other species included microsporum gypseum and trichophyton mentagrophytes. minimum inhibitory concentrations (mics) and minimum ... | 2002 | 12058731 |
| yeasts of the genus candida are the dominant cause of onychomycosis in libyan women but not men: results of a 2-year surveillance study. | the reported frequency of recovery of fungi from infected nails varies according to the geographical area. | 2002 | 12072073 |
| evaluation of the efficacy of oral lufenuron combined with topical enilconazole for the management of dermatophytosis in catteries. | the efficacy of oral lufenuron, a chitin synthetase inhibitor, combined with topical enilconazole, was evaluated for the management of microsporum canis infection in 100 cats housed in two catteries in france. the cats were treated with weekly rinses with enilconazole (0.2 per cent) for four weeks and, in each cattery, one group (a) was also treated with micronised griseofulvin (25 mg/kg administered orally twice a day for five weeks) and a second group (b) was treated with 60 mg/kg lufenuron ad ... | 2002 | 12081306 |
| use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes. | the sensititre yeastone antifungal panel was used to test 49 dermatophytes belonging to the species epidermophyton floccosum, microsporum gypseum, microsporum canis, trichophyton tonsurans, trichophyton rubrum, and trichophyton mentagrophytes. the mics of four antifungals obtained with the sensititre yeastone antifungal panel were compared with those obtained by the reference nccls microdilution method. the levels of agreement between the two methods (<or=2 dilutions) were 81.6% with amphoterici ... | 2002 | 12089289 |
| [morphological study of human hair infected with microsporum canis]. | some aspects in forensic medical examination of hairs damaged by microsporum canis are discussed. the data of microscopic, fluorescent, and serological studies of damaged hairs and methods for their examination are presented. | 2002 | 12165955 |
| terbinafine: efficacy and tolerability in young children with tinea capitis due to microsporum canis. | we carried out an open, prospective, uncontrolled study to evaluate the efficacy and tolerability of terbinafine in the treatment of young children with tinea capitis due to microsporum canis. | 2002 | 12195561 |
| survey of dermatophyte infections in the lausanne area switzerland. | the dermatophytes are important in the swiss medical environment since 5-10% of consultations in dermatology concern mycotic infections. | 2002 | 12218248 |
| secreted metalloprotease gene family of microsporum canis. | keratinolytic proteases secreted by dermatophytes are likely to be virulence-related factors. microsporum canis, the main agent of dermatophytosis in dogs and cats, causes a zoonosis that is frequently reported. using aspergillus fumigatus metalloprotease genomic sequence (mep) as a probe, three genes (mep1, mep2, and mep3) were isolated from an m. canis genomic library. they presented a quite-high percentage of identity with both a. fumigatus mep and aspergillus oryzae neutral protease i genes. ... | 2002 | 12228297 |
| unusual presentation of microsporum canis in human hair. | this study reports an unusual presentation of microsporum canis in infected human hair in a three-year-old boy. infected hairs showed ectothrix colonization with a mass of small conidia and numerous macroconidia typical of the genus microsporum. the infected hairs also showed strong invasion by hyphae bearing small numbers of arthroconidia. these hyphae were thinner and longer than those normally found in hair and scalp. it is well known that in cases of tinea capitis due to m. canis, ectothrix ... | 2002 | 12230223 |
| chemical analysis and antifungal activity of the essential oil of calea clematidea. | the chemical composition of the essential oils of calea clematidea baker obtained by hydrodistillation of the leaves and flowers was analysed by gc and gc/ms and the oils were assayed for their antifungal activities. the essential oil of the leaves showed a high content of a new natural epoxy terpenoid, named clemateol (ca. 70 %), with minor amounts of o-vanillin (6.5 %), spathulenol (4.2 %), alpha-terpinene (4.0 %), germacrene b (2.9 %), yomogi alcohol (1.8 %), ( e)-caryophylene (1.7 %), m-cyme ... | 2002 | 12357399 |
| antifungal evaluation of bis mannich bases derived from acetophenones and their corresponding piperidinols and stability studies. | the development of resistance to current antifungal therapeutics drives the search for effective new agents. the fact that some acetophenone-derived mannich bases had shown antifungal activities in our previous studies led us to design and synthesize acetophenone-derived bis mannich bases, b1-b5, bis(beta-aroylethyl)methylamine hydrochlorides, to evaluate their antifungal activity. these bis mannich bases were then converted to the corresponding piperidinols, c1-c5, which are structural isomers ... | 2002 | 12392084 |
| isolation of a microsporum canis gene family encoding three subtilisin-like proteases expressed in vivo. | microsporum canis is the main agent of dermatophytosis in dogs and cats and is responsible for frequent zoonosis. the pathogenesis of the disease remains largely unknown, however. among potential fungal virulence factors are secreted keratinolytic proteases, whose molecular characterization would be an important step towards the understanding of dermatophytic infection pathogenesis. m. canis secretes a 31.5 kda keratinolytic subtilisin-like protease as the major component in a culture medium con ... | 2002 | 12406327 |
| safety and immunologic effects after inoculation of inactivated and combined live-inactivated dermatophytosis vaccines in cats. | to determine antidermatophyte immunologic effects of an experimental combined live-inactivated dermatophytosis vaccine (clidv) and a commercial inactivated dermatophytosis vaccine (idv) in cats and to evaluate adverse effects associated with administration of these vaccines. | 2002 | 12428663 |
| fluconazole downregulates metallothionein expression and increases copper cytotoxicity in microsporum canis. | azole antifungals are widely used to treat infections with dermatophyte fungi. whereas it is well established that this class of drugs interferes with fungal ergosterol synthesis, little is known about its potential other biological effects. here we report the isolation and structural organization of microsporum canis metallothionein gene and demonstrate that fluconazole is able to downregulate the baseline as well as copper-induced expression of this gene. since this effect occurred within 30 m ... | 2002 | 12470632 |
| involvement of tnf-alpha changes in human cancer development, prevention and palliative care. | cancer development and ageing are complex sciences. from the study on the process of rodent carcinogenesis, we identified tumor necrosis factor-alpha (tnf-alpha) as an important mediator of cancer development. this paper presents three clinical examples of tnf-alpha up-regulation: by cord factors of mycobacterium tuberculosis, such as trehalose 6-monomycolate, as an activator of protein kinase c and by a cord factor like fraction of microsporum canis obtained in the air inside houses in thailand ... | 2002 | 12470903 |
| in vitro antimicrobial activity of ethanol and water extracts of cassia alata. | crude ethanol and water extract of leaves and barks from cassia alata were tested in vitro against fungi, (aspergillus fumigatus and microsporum canis), yeast (candida albicans) and bacteria (staphylococcus aereus and escherichia coli). c. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. the degree of susceptibility varied, the water extract from barks showed bigger inhibition zone tha ... | 2003 | 12499068 |
| fluconazole in the treatment of pediatric tinea capitis caused by microsporum canis. | fluconazole has been shown to be effective in the treatment of fungal scalp infections in children; however, there is limited experience of its use in microsporum scalp infections. we studied 11 children with tinea capitis caused by microsporum canis who received oral fluconazole at a dose of 5-7.5 mg/kg/day for 6 weeks. mycological cure was observed in two of the 11 patients at week 4 from the start of therapy, in four patients at week 8 and in three patients at week 16. one of the remaining pa ... | 2002 | 12512234 |
| tinea capitis in cleveland: survey of elementary school students. | tinea capitis, a fungal infection of the scalp, is of increasing public health importance, and trichophyton tonsurans has become the primary causative agent in north america. | 2003 | 12582387 |
| synergistic inhibition of the growth in vitro of microsporum canis by miconazole and chlorhexidine. | an agar dilution technique was used to assess the minimum inhibitory concentrations (mic) of miconazole, chlorhexidine and a 1:1 combination of both agents for 10 isolates of microsporum canis. for nine of 10 of the isolates, a combination of miconazole and chlorhexidine was more effective than either agent alone; fractional inhibitory concentration indices indicated a synergistic effect for five isolates and an additive effect for four. these results illustrate the potent antimycotic effect of ... | 2003 | 12662267 |
| characteristics of superficial mycoses in malta. | a study was conducted to determine the chief agents of superficial mycoses in malta. data were collected over a 5-year period from mycologic investigations carried out on all dermatologic specimens sent to the mycology laboratory at st. luke's hospital in malta. | 2003 | 12694490 |
| dermatophytes isolated from symptomatic dogs and cats in tuscany, italy during a 15-year-period. | between january, 1, 1986 and december, 31, 2000, dermatological specimens from 10.678 animals (7.650 cats and 3.028 dogs) were examined for dermatophytes. all the animals presented clinical signs of ringworm. two thousand-four hundred fifty-six of the 10.678 (23%) examined animals scored positive for dermatophytes, 566 out of 3.028 canine (18.7%) and 1890 out of 7.650 feline specimens (24.7%). microsporum canis constituted 83% and 97% of the isolated dermatophytes respectively in dogs and cats, ... | 2002 | 12715942 |
| [clinical and epidemiological survey of dermatophytoses in jaen (spain)] | prevalence of dermatophytosis, with respect to age and sex and dermatophyte species, in jaen was investigated during a period of three years (1996-1999). the prevalence of dermatophytosis over three years was 4.48 cases / 1000 inhabitants. the isolated species were: microsporum canis (48.6%), trichophyton mentagrophytes (27.1%), epidermophyton floccosum (10%), trichophyton rubrum (8.6%), trichophyton violaceum (4.3%), and microsporum gypseum (1.4%). the most frequently observed dermatophytoses w ... | 2002 | 12716229 |
| in vitro antagonistic activity of monoterpenes and their mixtures against 'toe nail fungus' pathogens. | the antibiotic effect of the active ingredients in meijer medicated chest rub (eucalyptus oil, camphor and menthol) as well as the inactive ingredients (thymol, oil of turpentine, oil of nutmeg and oil of cedar leaf) were studied in vitro using the fungal pathogens responsible for onychomycosis, such as the dermatophytes tricophyton rubrum, trichophyton mentagrophytes, microsporum canis, epidermophyton fl occosum and epidermophyton stockdale. the zones of inhibition data revealed that camphor (1 ... | 2003 | 12722144 |
| effects of lufenuron treatment in cats on the establishment and course of microsporum canis infection following exposure to infected cats. | to determine effects of lufenuron treatment in cats on the establishment and course of microsporum canis infection following exposure to infected cats. | 2003 | 12725307 |
| fluorescent method for studying the morphogenesis and viability of dermatophyte cells. | the dermatophyte microsporum canis is commonly isolated from human and animal infection. the morphogenesis of this fungus was studied during its developmental stages through the fluorescent method fluorescein diacetate and ethidium bromide. to this end, 50 microl dermatophyte suspension were transferred onto cellophane wrapping esterilized discs (2.5 cm of diameter) placed over the surface of sabouraud dextrose agar on petri dishes and incubated at 25 degrees c for 30 days. every 60 minutes duri ... | 2003 | 12733625 |
| the prevalence of immediate and delayed type hypersensitivity reactions to microsporum canis antigens in cats. | spontaneous recovery from microsporum canis infections in cats is thought to be dependent on the development of a competent immune response. the purpose of this study was to determine the prevalence of positive delayed type hypersensitivity reactions in cats with and without dermatophytosis. four groups of cats were intradermally skin tested with m canis extract and test sites were evaluated both subjectively and objectively at 0, 24 and 48 h after injection. delayed intradermal testing (idt) re ... | 2003 | 12765626 |
| dermatomycoses in the rijeka area, croatia, before, during and after the war 1990-1999. | the frequency of dermatomycoses as well as the spectrum of causative agents in the rijeka area, northwestern part of croatia, in the periods before and during the war (1990-1994) and in the postwar period (1995-1999) were analyzed. a total of 20 463 patients with clinically suspected dermatomycoses referred to the department of dermatovenerology, clinical hospital center rijeka, was examined. in the period from 1990 till 1994, 2462 samples were positive, compared with 2250 positive samples durin ... | 2003 | 12801365 |
| prevalence of tinea capitis in primary schools in turkey. | the aim of our study was to determine the prevalence of tinea capitis in middle anatolia. between february 2000 and april 2000, a school survey of 4760 primary school children was carried out and 34 cases of tinea capitis were clinically diagnosed. sixteen (0.3%) of them were diagnosed both clinically and using culture. eighteen cases (52.9%) were diagnosed microscopically whereas the remaining 16 cases (47.0%) had a clinical diagnose. we also isolated and identified the following species of fun ... | 2003 | 12801366 |
| dermatophytes isolated from domestic animals in iran. | between 1994 and 1998, a total of 790 feather, hair and skin specimens from a variety of animals with suspected dermatophytoses were studied, of which 248 (31.4%) yielded dermatophytes. the most frequent dermatophytes isolated were microsporum canis (38.3%), trichophyton verrucosum (31.8%), t. mentagrophytes (13.3%) and m. gypseum (7.7%). there was a significantly higher proportion of positive cultures from cats (54.8%) than dogs (8.2%), and m. canis was the most common species isolated (87.2 an ... | 2003 | 12801367 |
| [prevalence of zoophilic dermatophytes in the sarajevo region]. | zoophlic dermatophytes are common cause of tinea infections in europe, especially in mediterranean area. the aim of our study was to determine the prevalence of zoophilic dermatophytes in sarajevo area, during a five-year period (1998-2002). samples (skin scrapings or nail fragments) were taken from 2,142 patients who presented with suspected dermatophytoses and cultured on sabouraud agar. after three weeks of incubations 465 (21.7%) dermatophytes were identified based on macroscopic and microsc ... | 2003 | 12822383 |
| [three years incidence of dermatophytes in a hospital in porto (portugal)]. | we evaluated the incidence of dermatophytes isolated at our hospital in the years of 1997 to 2000 and correlated it with anatomical site and age. trichophyton rubrum was the predominant species in all anatomical sites, excluding scalp, followed by microsporum canis, the leading agent of tinea capitis. all dermatophytosis, except tinea capitis by m. canis and trichophyton schoenleinnii appeared mainly in adult patients. our results revealed no substantial differences to other portuguese studies r ... | 2002 | 12825982 |
| antifungal activity of the methanolic extract and alkaloids of glaucium oxylobum. | the methanolic extract and total alkaloids of the aerial parts of glaucium oxylobum exhibited good activity against microsporum gypseum, microsporum canis, trichophyton mentagrophytes and epidermophyton floccosum. four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compounds responsible for the antifungal activity of this plant. | 2003 | 12837370 |
| onychomycosis in systemic lupus erythematosus: a case control study. | immunosuppressed patients are prone to develop onychomycosis. in systemic lupus erythematosus (sle) there are no previous studies. we aimed to establish the prevalence, clinical characteristics, and organisms causing onychomycosis in sle patients compared with controls. | 2003 | 12858446 |
| inhibition of dermatophytes by optical brighteners. | the aim of this study was to investigate a possible effect of optical brighteners on the growth of dermatophytes. typical strains of trichophyton rubrum, t. mentagrophytes, microsporum canis and epidermophyton floccosum were grown on agar plates containing two different brighteners of stilbenedisulfonic acid type in concentrations between 5 x 10(-5) and 1 x 10(-2) mol l-1 and their thallus diameters were compared with controls. in addition, hyphae grown with brighteners were compared with contro ... | 2003 | 12870200 |
| recombinant expression and antigenic properties of a 31.5-kda keratinolytic subtilisin-like serine protease from microsporum canis. | a secreted 31.5-kda keratinolytic subtilase (sub3; aj431180) is thought to be a microsporum canis virulence factor and represents a candidate for vaccination trials. in this study, the recombinant keratinase (r-sub3) was produced by the pichia pastoris expression system and purified to homogeneity. recombinant sub3 displayed identical biochemical properties with the native protease. experimentally cutaneously infected guinea pigs showed specific lymphoproliferative response towards r-sub3, while ... | 2003 | 12900052 |
| [analysis of dermatophyte flora at a private clinic in sapporo during the period 1992 to 2001]. | statistical analysis was made of a total of 5530 patients (6798 cases) of dermatophytoses presenting at our private clinic during the period 1992 to 2001. the number of patients and cases represents 8.0% and 9.8% of the entire outpatient population during that time, respectively. sex ratio (male/female) was 1.5. among the 6798 dermatophytoses cases, tinea pedis was most frequent (65.8%), followed by tinea unguium (20.7%), tinea cruris (7.2%), tinea corporis (3.9%), tinea manuum (2.4%) and tinea ... | 2003 | 12913811 |
| presence of dermatophytes on the nails of tinea capitis patients. prospective study in the area of sfax (tunisia). | between january 1995 and december 2000, 512 cases with mycologically confirmed tinea capitis have been diagnosed in our laboratory. in addition, finger nail samples have been taken from 211 patients out of 512. the culture of the nail samples taken was positive for 80 patients (38%). the isolated dermatophytes were the same in the nails and the scalp. microsporum canis was isolated in 82% of nail samples. trichophyton violaceum grew only in 18% and trichophyton quinckeanum in one case. a t. viol ... | 2003 | 12950904 |
| [tinea capitis et corporis due to microsporum canis in an immunocompromised female adults patient]. | tinea capitis as well as tinea corporis in adults may occur under conditions of immunosuppression. if suspected clinically, direct microscopy and examination by culture is indispensable. therapeutic intervention should start without delay. a proven fungal infection of scalp hairs warrants immediate initiation of systemic treatment. hereby prevention of disfiguring hair loss, permanent formation of scar tissue, spread of fungal organisms to other cutaneous regions as well as infection of other pe ... | 2003 | 12955848 |
| bioactive alkyl phenols and embelin from oxalis erythrorhiza. | the benzoquinone embelin and four alkyl phenols were isolated from an argentinean collection of oxalis erythrorhiza. 3-heptadecyl-5-methoxy-phenol is reported for the first time. the structures were determined by spectroscopic methods. embelin presented inhibitory effect on methicillin-resistant staphylococcus aureus, escherichia coli and the dermatophytic fungi epidermophyton floccosum, microsporum canis, microsporum gypseum, trichophyton mentagrophytes and trichophyton rubrum with mics ranging ... | 2003 | 12963150 |
| a liquid synthetic medium suitable for the differentiation of microsporum audouini gruby 1843, and of microsporum canis bodin 1902. | | 1952 | 12978206 |
| structures resembling fuseaux in a case of ringworm of the scalp due to microsporum canis bodin and microsporum audouini gruby. | | 1953 | 13032318 |
| the digestion of human hair keratin by microsporum canis bodin. | | 1953 | 13044911 |
| the treatment of microsporum canis infection of the scalp with dibromopropamidine isethionate. | | 1952 | 13081520 |
| tinea capitis caused by microsporum canis; report of an outbreak in a dunedin institution. | | 1954 | 13166008 |
| experimental microsporum canis infections in kittens. | | 1956 | 13283230 |
| the ecology of microsporum canis bodin in new zealand. | | 1956 | 13367404 |
| tinea capitis (microsporum canis) in a thirty-day-old infant. | | 1957 | 13443516 |
| [microsporum canis infections in the area of hamburg]. | | 1957 | 13461554 |
| microsporum canis; an intensive outbreak. | | 1957 | 13472074 |
| [microsporia epidemic due to microsporum canis transmitted by cats in kaiserslautern]. | | 1958 | 13534398 |
| [rare infections caused by trichophyton schönleinii (lebert) langeron & milochevitch (1930) & microsporum canis bodin (1902) occuring in germany with remarks on their nomenclature]. | | 1958 | 13548710 |
| [the value of the animal experiment in the differentiation of microsporum audouini from microsporum canis]. | | 1958 | 13548714 |
| epidemic due to microsporum canis. | | 1958 | 13582197 |
| [rapid cure of ringworm of the scalp caused by microsporum canis with an acid pomade & iodine]. | | 1958 | 13608248 |