| isolation of secondary metabolites of aspergillus ochraceus by hplc. | a method is described for the isolation and purification of ochratoxin a, ochratoxin b, ochratoxin ß mellein, 4-hydroxymellein and penicillic acid produced byaspergillus ochraceus in a synthetic liquid medium. ochratoxin α, which was not found in the culture medium, was obtained by acid hydrolysis of ochratoxin a. a high pressure liquid chromatograph equipped with lichrosorb 100 and lichrosorb rp-18 columns and uv and/or refractive index detectors was used. | 1986 | 23604831 |
| edible wild plant heracleum pyrenaicum subsp. orsinii as a potential new source of bioactive essential oils. | many heracleum l. taxa (apiaceae) are used as food and spices, and in traditional medicine. in this work, the chemical composition of heracleum pyrenaicum subsp. orsinii (guss.) f. pedrotti and pignatti root, leaf and fruit essential oils, their antimicrobial activity and cytotoxic effect on malignant and normal cells were investigated for the first time. the composition of the oils was analyzed by gc and gc-ms. monoterpenes prevailed in the root oil, with β-pinene (38.6%) being dominant, while ... | 2017 | 28740275 |
| obtaining of 11α-hydroxyandrost-4-ene-3,17-dione from natural sterols. | two-step one-pot microbial transformation enables obtaining of valuable steroids that are difficult to produce chemically. here we describe a method for obtaining 11α-hydroxyandrost-4-ene-3,17-dione (11α-had) from cheap and available natural sterols (phytosterols or cholesterol).11α-had is a primary adrenal steroid in mammals and also a key precursor in the syntheses of halogenated corticoids. conventional routes for its obtaining are based on chemical synthesis, or microbial hydroxylation of an ... | 2017 | 28710634 |
| aspergillus nodules in chronic granulomatous disease attributable to aspergillus ochraceus. | aspergillus ochraceus is a rare pulmonary pathogen. a 39 year old male with copd and chronic granulomatous disease presented with severe breathlessness and recurrent infections. ct scan demonstrated multiple pulmonary nodules diagnosed as chronic pulmonary aspergillosis. the patient's sputum grew aspergillus ochraceus thrice over 6 months, alongside positive aspergillus igg and serum galactomannan. despite treatment with itraconazole, the patient continued to be symptomatic. we present the first ... | 2017 | 28702318 |
| fungal levels in houses in the fukushima daiichi nuclear power plant evacuation zone after the great east japan earthquake. | residences located within 20 km of the damaged fukushima daiichi nuclear power plant were evacuated shortly after the great east japan earthquake. the levels of airborne and surface fungi were measured in six houses in the evacuation zone in august 2012 and february 2013. airborne fungal levels in all of the houses in the summer were higher than the environmental standard levels for residential houses published in architectural institute of japan (>1,000 cfu/m(3)). in two houses whose residents ... | 2017 | 28541772 |
| uplc-ms-it-tof identification of circumdatins produced by aspergillus ochraceus. | a method based on the combined use of ultraperformance liquid chromatography coupled to mass spectrometry-ion trap-time-of-flight (uplc-ms-it-tof) detection was employed to identify the metabolite production of aspergillus ochraceus, which is the major cause of food and feed contamination due to ochratoxin a. under the proposed chromatographic conditions, seven metabolites belonging to the family of circumdatins were separated and identified. their initial identification was performed through th ... | 2017 | 28535676 |
| infant origins of childhood asthma associated with specific molds. | the specific cause or causes of asthma development must be identified to prevent this disease. | 2012 | 22789397 |
| apoptosis and lipid peroxidation in ochratoxin a- and citrinin-induced nephrotoxicity in rabbits. | ochratoxin a (ota) and citrinin (cit) are nephrotoxic mycotoxins produced mainly by fungal species aspergillus ochraceus and penicillium citrinum, respectively, which have been found to occur together in various food and feed commodities. in the present study, both ota and cit were evaluated for their potential to induce oxidative damage by determining lipid peroxidation (lpo) through malondialdehyde (mda) assay and apoptosis by flow cytometry, gel electrophoresis and renal ultrastructural morph ... | 2014 | 22773436 |
| aoyap1 regulates ota synthesis by controlling cell redox balance in aspergillus ochraceus. | among the various factors correlated with toxin production in fungi, oxidative stress is a crucial one. in relation to this, an important role is played by oxidative stress-related receptors. these receptors can transduce the "oxidative message" to the nucleus and promote a transcriptional change targeted at restoring the correct redox balance in the cell. in aspergillus parasiticus, the knockout of the apyapa gene, a homologue of the yeast yap-1, disables the fungus's capacity to restore the co ... | 2012 | 22410746 |
| production of xylanase and β-xylosidase from autohydrolysis liquor of corncob using two fungal strains. | agroindustrial residues are materials often rich in cellulose and hemicellulose. the use of these substrates for the microbial production of enzymes of industrial interest is mainly due to their high availability associated with their low cost. in this work, corncob (ccs) particles decomposed to soluble compounds (liquor) were incorporated in the microbial growth medium through autohydrolysis, as a strategy to increase and undervalue xylanase and β-xylosidase production by aspergillus terricola ... | 2012 | 22367528 |
| inactivation of a. ochraceus spores and detoxification of ochratoxin a in coffee beans by gamma irradiation. | ochratoxin a (ota) produced in food by aspergillus ochraceus is known to cause adverse health effects. among the plantation products, green coffee beans are prone to fungal attack and get contaminated with ota frequently. a fungal strain isolated from green coffee beans was characterized by morphological analyses as well as internal transcribed spacer (its) and 5.8s rdna sequencing, turned out to be a. ochraceus, however, nontoxigenic. hence, additional strains of a. ochraceus were procured and ... | 2012 | 22339551 |
| analytical characterization and structure elucidation of metabolites from aspergillus ochraceus mp2 fungi. | to isolate and characterize the bioactive secondary metabolites from aspergillus ochraceus (a. ochraceus) mp2 fungi. | 2011 | 23569796 |