| bartonella henselae induces nf-kappab-dependent upregulation of adhesion molecules in cultured human endothelial cells: possible role of outer membrane proteins as pathogenic factors. | the endothelium is a specific target for bartonella henselae, and endothelial cell infection represents an important step in the pathogenesis of cat scratch disease and bacillary angiomatosis. mechanisms of bartonella-endothelial cell interaction as well as signaling pathways involved in target cell activation were analyzed. b. henselae strain berlin-1, isolated from bacillary angiomatosis lesions of a human immunodeficiency virus-infected patient, potently stimulated human umbilical cord vein e ... | 2001 | 11447190 |
| [bartonella henselae meningoencephalitis]. | | 2001 | 11458191 |
| an epitrochlear tumour. | | 2001 | 11461986 |
| epidemiologic and clinical characteristics of bartonella quintana and bartonella henselae endocarditis: a study of 48 patients. | | 2001 | 11470985 |
| immunofluorescent detection of intraerythrocytic bartonella henselae in naturally infected cats. | to determine the presence of bartonella henselae bacteremia in six cats, we compared isolation using blood culture with direct immunofluorescence on blood smears. three cats that were positive by blood culture were also positive by direct immunofluorescence, and laser confocal microscopy confirmed the intraerythrocytic location of b. henselae. | 2001 | 11474027 |
| serodiagnosis of cat scratch disease: response to bartonella henselae in children and a review of diagnostic methods. | in this study, sera from 116 children without clinical evidence of cat scratch disease (csd) and sera from 19 children with csd were investigated by two different immunofluorescent assays (test a and test b) to evaluate the seroprevalence of bartonella henselae antibodies in this population. antibodies against bartonella henselae were found in noninfected children only in low titers: 13% and 3.5% of serum samples were positive by test a and test b, respectively. igg titers as determined by test ... | 2001 | 11476439 |
| evaluation and use of a nested polymerase chain reaction assay in cats experimentally infected with bartonella henselae genotype i and bartonella henselae genotype ii. | cats have been shown to be infected with bartonella henselae genotype i, b. henselae genotype ii, and b. clarridgeiae. feline bartonellosis infections and the strains involved in these infections are important in both veterinary and human medicine. nucleic acid amplification methods such as polymerase chain reaction (pcr) are being used in both research and diagnostics as tools for understanding many infectious diseases. bartonella bacteremia in cats is detected by blood culture; however, becaus ... | 2001 | 11478603 |
| cat-scratch disease: considerations for dentistry. | cat-scratch disease, or csd, results from inoculation of the gram-negative bacillus bartonella henselae via a cat's scratch. a regional lymphadenitis, which usually is cervical, develops and may progress to suppuration. it is necessary to differentiate csd from other lymphadenopathies. | 2001 | 11480644 |
| differential detection of bartonella species and strains in cat scratch disease diagnostics by polymerase chain reaction amplification of 16s ribosomal rna gene. | cat scratch disease (csd) has been difficult to diagnose in animals because of the protracted clinical course of infection and the quiescent phases when the microbial culprit lies dormant. the causative agent in csd appears to be multiple species and strains of bartonella. using polymerase chain reaction (pcr) techniques for amplification of highly variable regions of the 16s ribosomal rna (rrna) gene sequence, a very sensitive species- and strain-specific assay for csd-causing bartonella specie ... | 2001 | 11482599 |
| acute endogenous endophthalmitis due to bartonella henselae. | a 45-year-old man presented with progressively worsening vitreitis of 1 week's duration. treatment for cat-scratch disease 3 years prior to presentation and persistent vitreitis led to vitrectomy, and analysis of the vitrectomy specimen revealed inflammatory cells and necrotic debris; polymerase-chain-reaction analysis of the vitreous fluid sample, done by use of a novel heminested protocol, demonstrated the presence of bartonella henselae dna. treatment with doxycycline led to improvement in th ... | 2001 | 11486295 |
| [an adult case of systemic cat-scratch disease with hepatosplenic involvement]. | a previously healthy 25-year-old female was admitted to our hospital in november, 1997, for treatment of a spike-fever of 2 weeks' duration. she had a cat in her house but reported no history of cat bites or scratches. no peripheral lymphadenopathy was detected. white blood cell count was within normal limits, but an increased c-reactive protein level of 11.4 mg/dl was noted. infectious disease was suspected but ruled out as blood cultures were negative. empiric therapy with clarithromyoin, ison ... | 2001 | 11494569 |
| [bartonella henselae endocarditis. report of a case and review of the literature]. | bartonella spp are small gram-negative rods, aerobic and highly fastidious. they are difficult to culture, in the routine bacterial cultures. they are considered as emergent human pathogens. since 1993, three species of bartonella (b. quintana, b. henselae, and b. elizabethae) have been described as causative agents of infectious endocarditis. in this paper we describe the case of a 43 year-old woman with a previous valvular heart disease, probably of rheumatic origin, owner of cats, that suffer ... | 2001 | 11496560 |
| probable atypical cat scratch disease presenting as isolated posterior pancreatic duodenal lymphadenitis and abdominal pain. | we report a case involving a 15-year-old girl with atypical, clinically unsuspected cat scratch disease (csd) presenting as isolated posterior pancreatic duodenal lymphadenitis, fever, and abdominal pain. the serological, abdominal ultrasonographic, and ct findings, as well as clinical and epidemiological data, indicate that b. henselae was likely an etiologic agent of csd in our patient. | 2001 | 11512100 |
| circulating cytokines in patients with cat scratch disease. | levels of circulating interleukin (il)-2, il-6, and il-10, measured by enzyme-linked immunosorbent assay, were significantly higher in patients with cat scratch disease (csd) than in healthy control subjects; no induction of il-12 was observed, and levels of interferon-gamma and il-4 were generally not detectable. this is the first report showing increased circulating cytokine levels in patients with csd. the induction of these mediators can partly explain some clinical and pathological features ... | 2001 | 11512109 |
| [cat scratch disease showing clinical picture resembling tuberculous lymphadenitis: a case report]. | on february 18th, 1997, a 61-year-old woman visited our hospital because of a left inguinal mass. on physical examination, the mass was soft without inflammatory sign. about one month later, the node was excised. pathological examination revealed granulomas with caseous necrosis and langhans giant cells, suggesting tuberculosis, although acid fast stain was negative. thereafter, re-history taking in detail disclosed that a kitten had often scratched her. we reexamined the pathology and checked h ... | 2001 | 11517562 |
| [longitudinal study of serological response to bartonella henselae by indirect fluorescence assay in cat scratch disease]. | sequential serologic testing for igg and igm titers to bartonella henselae were evaluated by an indirect fluorescence assay (ifa) in patients with csd. the ifa test for the detection of igg and igm antibodies to b. henselae in 52 csd patients showed that 40 (76.9%) were positive for igg antibody and 9 (17.3%) were positive for igm antibody. two or more consecutive serum samples from 30 patients with csd were assessed. in regard to the detection of igg antibody, 5 patients had rapidly elevated ti ... | 2001 | 11521278 |
| bartonella henselae serostatus is not correlated with neurocognitive decline in hiv infection. | bartonella henselae has been implicated as a significant cause of hiv-associated dementia. we attempted to confirm this association by utilizing the database of the san diego hiv neurobehavioral research center, which collects longitudinal neurocognitive and laboratory data on over 500 hiv-infected participants. utilizing an immunofluorescent assay we found that 11% of 177 subjects, half of whom had documented neurocognitive decline, were seropositive for b. henselae. there was no correlation be ... | 2001 | 11525353 |
| unsuspected extralymphocutaneous dissemination in febrile cat scratch disease. | cat scratch disease (csd) commonly manifests as regional self-limited lymphadenitis. however, dissemination of the infection to distant multiple sites may occur even in immunocompetent patients. we report a series of 11 children with fever and extralymphocutaneous manifestations of csd, in order to highlight potential multiorgan involvement in patients with febrile csd. to be eligible for enrollment, patients had to present with involvement of sites other than regional lymph nodes. the diagnosis ... | 2001 | 11525355 |
| native valve endocarditis due to bartonella henselae in a middle-aged human immunodeficiency virus-negative woman. | we report the case of a human immunodeficiency virus-negative woman who developed native valve endocarditis of the aortic valve due to bartonell henselae infection. the diagnosis was established using serology and pcr analysis of excised aortic valve tissue. | 2001 | 11526194 |
| seroprevalence of antibodies to microorganisms known to cause arterial and myocardial damage in patients with or without coronary stenosis. | infections are assumed to play a role in coronary artery disease (cad) and cardiomyopathies. it is unknown whether the seroprevalence of antibodies to these microorganisms is higher in patients with than without cad. the seroprevalence of antibodies to bartonella henselae, borrelia burgdorferi, chlamydia pneumoniae, coxiella burnetii, helicobacter pylori, human granulocytic ehrlichia, leptospira, rickettsia conorii, and treponema pallidum was assessed prospectively in patients with exertional dy ... | 2001 | 11527817 |
| bartonella henselae neuroretinitis. | | 2001 | 11531989 |
| identification, characterization, and functional analysis of a gene encoding the ferric uptake regulation protein in bartonella species. | environmental iron concentrations coordinately regulate transcription of genes involved in iron acquisition and virulence via the ferric uptake regulation (fur) system. we identified and sequenced the fur gene and flanking regions of three bartonella species. the most notable difference between bartonella fur and other fur proteins was a substantially higher predicted isoelectric point. no promoter activity or fur autoregulation was detected using a gfp reporter gene fused to the 204 nucleotides ... | 2001 | 11544240 |
| evidence of a leading role for vegf in bartonella henselae-induced endothelial cell proliferations. | bartonella henselae causes the vasculoproliferative disorders bacillary angiomatosis (ba) and bacillary peliosis (bp). the pathomechanisms of these tumorous proliferations are unknown. our results suggest a novel bacterial two-step pathogenicity strategy, in which the pathogen triggers growth factor production for subsequent proliferation of its own host cells. in fact, b. henselae induces host cell production of the angiogenic factor vascular endothelial growth factor (vegf), leading to prolife ... | 2001 | 11553014 |
| interaction of bartonella henselae with the murine macrophage cell line j774: infection and proinflammatory response. | bartonella henselae is the causative agent of cat scratch disease (csd), a self-limiting condition characterized by a subacute regional lymphadenopathy that may develop into disseminated bartonellosis in immunocompromised subjects. mice experimentally infected with b. henselae display typical liver and spleen granulomas rich in t cells and macrophages. so far there are no data on the interaction between bartonellae and macrophages. in order to clarify this topic, we investigated the interaction ... | 2001 | 11553533 |
| bartonella henselae-specific cell-mediated immune responses display a predominantly th1 phenotype in experimentally infected c57bl/6 mice. | immune responses of the immunocompetent host to bartonella henselae infection were investigated in the murine infection model using c57bl/6 mice. following intraperitoneal infection with human-derived b. henselae strain berlin-1, viable bacteria could be recovered from livers and spleens during the first week postinfection, while bartonella dna remained detectable by pcr in the liver for up to 12 weeks after infection. granulomatous lesions developed in livers of infected mice, reached maximal d ... | 2001 | 11553587 |
| intracellular induction of the bartonella henselae virb operon by human endothelial cells. | one of the more recently identified bacterial exportation systems is the type iv secretion mechanism, which is characterized by a multiprotein complex that spans the inner and outer bacterial membranes and contains a pilin component. the most thoroughly studied type iv secretion system is encoded by the virb operon of agrobacterium tumefaciens. in bartonella henselae, 8 of the 10 virb operon genes share extensive homology and arrangement with the virb operon of a. tumefaciens. sequencing of the ... | 2001 | 11553594 |
| of fleas and ticks on cats and mice... | | 2001 | 11559304 |
| concurrent infection of the central nervous system by borrelia burgdorferi and bartonella henselae: evidence for a novel tick-borne disease complex. | to investigate bartonella henselae as a potential human tick-borne pathogen and to evaluate its role as a coinfecting agent of the central nervous system in the presence of neuroborreliosis. | 2001 | 11559306 |
| [splenic abscess and cat-scratch disease]. | cat-scratch disease is caused by a gram-negative bacillus known as bartonella henselae. this disease is usually benign and causes regional adenitis that does not require treatment. however, some patients develop more serious atypical forms of the disease including prolonged systemic illness with hepatic and splenic abscesses.a 14-year-old girl was admitted to hospital with a 12-day history of persistent high fever and abdominal pain. ultrasonography and computerized tomography of the abdomen rev ... | 2001 | 11578546 |
| bartonella henselae neuroretinitis in cat scratch disease. | | 2001 | 11587306 |
| cat-scratch disease neuroretinitis diagnosed by a polymerase chain reaction approach. | to assess the value of polymerase chain reaction in the diagnosis of cat-scratch disease neuroretinitis without conclusive serology. | 2001 | 11589885 |
| atypical presentations of cat scratch disease in the head and neck. | | 2001 | 11593185 |
| [infections caused by bartonella spp]. | | 2001 | 11602390 |
| [two patients with bartonella henselae infection from a dog]. | two patients were reported as having been infected with bartonella henselae after having contact with a dog. both of the patients owned a dog, but had no contact with cats. one patient was a 10-year-old boy who had experienced a fever of 38-39 degrees c for 11 days, as well as having bilateral cervical lymphadenopathy. the boy's serum igm antibodies to b. henselae were negative on the 6th and 16th day of his illness, whereas his igg value, using indirect fluorescence antibody (ifa) method, was f ... | 2001 | 11605190 |
| cat-scratch disease presenting as multifocal osteomyelitis with thoracic abscess. | the case of a 4-year-old girl who presented with fever and back pain after being scratched by a kitten is presented. the diagnosis of cat scratch disease osteomyelitis was made by the detection of bartonella henselae dna by pcr analysis of a rib abscess aspirate. | 2001 | 11642619 |
| possible role of high-dose corticosteroids in the treatment of cat-scratch disease encephalopathy. | approximately 2% of the estimated 24,000 patients in the united states who contract cat-scratch disease annually develop neurologic complications. between 1989 and 1999, 36 patients were admitted to our hospital with cat-scratch disease; 25% had neurologic complications, and the majority experienced lengthy hospital stays. we describe a case of cat-scratch disease encephalopathy in a 4-year-old girl who responded to high-dose corticosteroid therapy. further studies are warranted to determine if ... | 2001 | 11669351 |
| cat scratch disease. a cause of regional lymphadenitis. | in the last decade, the microbiological cause of cat scratch disease (csd) has been determined using a combination of traditional culture and modern molecular techniques. a bacterium known as bartonelia henselae is responsible for the vast majority of cases. the natural history of the disease is being reinterpreted in the light of more sophisticated diagnostic tools. | 2001 | 11681146 |
| survey of veterinary professionals for antibodies to bartonella henselae in japan. | the seroprevalence of bartonella henselae among veterinary professionals in japan was investigated by means of an immunoperoxidase (ip) test that used protein a-horseradish peroxidase conjugate. sera were obtained from 233 veterinary professionals in the tokyo and chiba areas. as negative control group, sera from 155 healthy individuals (all medical students) were used. as positive control group, sera from 5 patients highly suspected of cat scratch disease (csd) by clinical symptoms were tested. ... | 2001 | 11685779 |
| chronic active myocarditis following acute bartonella henselae infection (cat scratch disease). | an association between bartonella infection and myocardial inflammation has not been previously reported. we document a case of a healthy young man who developed chronic active myocarditis after infection with bartonella henselae (cat scratch disease). he progressed to severe heart failure and underwent orthotopic heart transplantation. bartonella henselae, therefore, should be included among the list of infectious agents associated with chronic active myocarditis. | 2001 | 11688584 |
| enzyme immunoassay for the diagnosis of cat-scratch disease defined by polymerase chain reaction. | whole-cell immunofluorescent antibody (ifa) tests for detection of anti-bartonella henselae immunoglobulin (ig) g are commonly used to diagnose cat-scratch disease (csd). the need to cultivate b. henselae in vero cells for antigen preparation and the absence of routinely applied ifa assays for igm constitute the major disadvantages of this form of test. we describe the results of an enzyme immunoassay (eia) for igm and igg that used n-lauroyl-sarcosine-insoluble outer membrane antigens from agar ... | 2001 | 11692296 |
| experimental infection and horizontal transmission of bartonella henselae in domestic cats. | in order to study b. henselae transmission among cats, five young cats were kept in confinement for two years, one of them being inoculated by sc route with b. henselae (10(5) ufc). only occasional contact among cats occurred but the presence of fleas was observed in all animals throughout the period. blood culture for isolation of bacteria, pcr-hsp and ftsz (gender specific), and bh-pcr (species-specific), as well as indirect immunofluorescence method for anti-b. henselae antibodies were perfor ... | 2001 | 11696847 |
| culture negative endocarditis combined with glomerulonephritis caused by bartonella species in two immunocompetent adults. | two cases of culture negative endocarditis are presented. in both, bartonella species could be identified as the causative agent and in one of them bartonella henselae was very likely. both cases were accompanied by glomerulonephritis, in one case proven by a kidney biopsy. a nephrotic syndrome may be the first presentation of an endocarditis caused by bartonella species. | 2001 | 11705641 |
| [unusual manifestations of bartonella infections]. | the authors review the cases of two patients with an atypical form of cat scratch disease. the first case exhibited ileocoecal and hepatoportal lymphadenitis, and the second case the emerging symptoms of a non-specific granulomatous process in the middle third of the right forearm, which caused a differential-diagnostic problem. establishment of a diagnosis was possible only on the basis of the disease process and the pathological, serological and histopathological pictures of the lymphatic glan ... | 2001 | 11706512 |
| [acute generalized cat scratch disease in myelodysplastic syndrome]. | in patients with normal immunity, cat scratch disease typically develop a papule at the portal of entry and no other cutaneous features. a 73 year old male patient with a myelodysplastic syndrome developed generalized petechial, papular and, vasculitic skin lesions in association with cat scratch disease. after the diagnosis was established by identifying the causative organism in a lymph node biopsy, the patient was treated with erythromycin for three weeks resulting in progressive clearance of ... | 2001 | 11715399 |
| cat scratch disease due to bartonella henselae infection mimicking parotid malignancy. | an unusual bartonella henselae infection presenting clinically as a putative parotid cancer was diagnosed based on serological tests, histomorphology and amplification of a 16s-rdna sequence of bartonella henselae. the patient improved greatly upon antibiotic treatment and did not require surgery. although uncommon, infection with bartonella spp., particularly bartonella henselae, should be included in the differential diagnosis of parotid tumors. | 2001 | 11757975 |
| cat scratch disease (bartonellosis) mimicking an sle flare. | only recently bartonella species have been recognized as important human pathogens. cat scratch disease (csd), caused by infection with bartonella henselae, shows a steady increase in the number of cases throughout the world. we report a case of an 18-year-old woman with systemic lupus erythematosus (sle) who presented with ongoing fever, arthralgias and loss of weight which did not respond to increasing doses of corticosteroids. after exclusion of common infections a photograph of her cat in co ... | 2001 | 11787880 |
| role of bartonella henselae in the etiology of henoch-schönlein purpura. | the etiology of henoch-schönlein purpura (hsp) has been ascribed to a variety of infectious and noninfectious agents. because we encountered a patient with hsp who had evidence of bartonella henselae infection and a prior report of a patient with systemic cat-scratch disease presenting as leukoclastic vasculitis, we investigated the association of b. henselae infection with hsp. | 2002 | 11791094 |
| prevalence of bartonella species and 16s rrna gene types of bartonella henselae from domestic cats in thailand. | prevalence of bartonella infection among 275 cats in 9 sites from 4 geographical regions (northern area: chiang mai; central area: kanchanaburi, ratchaburi, and bangkok; northeastern area: khon kaen, roi et, ubon ratcharthani, and nakhonratchasima; southern area: songkhla) of thailand was investigated. overall, bartonella species were isolated from 27.6% (76 of 275) of the cats. the isolation rate varied from 12.8% (5 of 39) in songkhla (southern area) to 50.0% (26 of 52) in khon kaen (northeast ... | 2001 | 11791975 |
| evidence of rodent-associated bartonella and rickettsia infections among intravenous drug users from central and east harlem, new york city. | we tested serum samples collected in 1997 and 1998 from a cohort of 204 injection drug users (idus) recruited from central and east harlem, new york city, new york, for antibodies reactive with seven rickettsial or bartonella spp. antigens. rodent-associated bartonella elizabethae and rickettsia akari were the primary etiologic agents of interest. the testing panel also included bartonella henselae, bartonella quintana, rickettsia prowazekii, rickettsia rickettsii, and rickettsia typhi. the high ... | 2001 | 11791987 |
| granuloma annulare: another manifestation of bartonella infection? | granuloma annulare (ga) is a common cutaneous eruption whose pathogenesis remains unknown. recent literature has suggested a relation between borrelia infection and ga, a relation that has not been widely accepted. earlier works attempted unsuccessfully to implicate various other infectious agents. some reports have demonstrated the increased frequency of ga in patients with human immunodeficiency virus infection, again raising the possibility of an infectious etiology. using polymerase chain re ... | 2001 | 11801791 |
| aortic valve endocarditis caused by bartonella henselae: a rare surgical entity. | we report a case of aortic valve endocarditis caused by bartonella henselae. the patient initially presented to a regional hospital with generalized symptoms including lethargy, malaise and decreased appetite. transthoracic echocardiogram revealed a large vegetation on the aortic valve and he was treated empirically with broad spectrum intravenous antibiotics. several blood cultures were obtained which all returned negative results and the white blood cell count was normal. he was transferred to ... | 2001 | 11803150 |
| [new and emerging rickettsial and bartonella infections]. | there have been recently reports on over 10 new and resurgent rickettsioses and bartonelloses in different countries, which reflects both socioeconomic processes in society and a higher methodological level of indication and identification of causative agents. in 1991, the author' laboratory, n. f. gamaleya research institute of experimental medicine, russian academy of medical sciences, established the etiology of the new rickettsiosis astrakhan spotted fever. it separated and studied 2 strains ... | 2001 | 11837209 |
| phylogenetic classification of bartonella species by comparing groel sequences. | bartonella is a bacterial genus classified in the alpha-proteobacteria on the basis of 165 rdna sequence comparison. the highly conserved heat-shock chaperonin protein, groel, has proved to be a valuable resolving tool to classify ten bartonella species. the groel gene was amplified and sequenced from ten bartonella isolates: bartonella alsatica, bartonella vinsonii subsp. arupensis, bartonella taylorii, bartonella tribocorum, bartonella birtlesii, bartonella henselae marseille (urlly8), b. hens ... | 2002 | 11837299 |
| autoimmune haemolytic anaemia triggered by bartonella henselae infection: a case report. | bartonella henselae is a hitherto unidentified cause of autoimmune haemolytic anaemia. here we report a case of coombs-negative autoimmune haemolytic anaemia. the episode was preceded by exposure to a cat and a non-specific infectious syndrome. concomitant serum titres of b. henselae antibodies were indicative of a recent infection. the case report suggests that b. henselae infection can trigger secondary autoimmune haemolytic anaemia. | 2001 | 11843827 |
| rapid allelic discrimination from real-time dna amplification. | a rapid method based on fluorescence resonance energy transfer and real-time polymerase chain reaction (pcr) is used to identify the factor v genotype or to identify the bacterial species bartonella qunitana or bartonella henselae. allelic discrimination was performed on the post-pcr product. thermal cyclers other than the 7700 sequence detection system can be used for pcr, after which the products can be transferred to the 7700 sequence detection system for measurement of fluorescence. the delt ... | 2001 | 11846614 |
| detection of bartonella henselae and bartonella quintana by a simple and rapid procedure using broad-range pcr amplification and direct single-strand sequencing of part of the 16s rrna gene. | objective: to detect directly bartonella henselae and bartonella quintana using culture-independent, molecular techniques, and to evaluate a simple and rapid procedure that allows uncultivable bacteria to be detected in usually sterile clinical specimens in a diagnostic laboratory. methods: from four clinical specimens proven to contain b. henselae (n=3) or b. quintana (n=1) dna, part of the 16s rrna gene was amplified using the polymerase chain reaction (pcr) and broad-range bacterial primers f ... | 1997 | 11864111 |
| bartonella henselae infection mimicking a splenic lymphoma. | we report a bartonella henselae infection in a 40-y-old patient who presented with fever, weight loss, night sweats, elevated lactate dehydrogenase and multinodular splenomegaly with multiple abdominal lymphadenopathies. splenic cat-scratch disease is an exceptional diagnosis in adults and can easily be mistaken for a splenic lymphoma, thereby leading to an unnecessary splenectomy. | 2001 | 11868771 |
| cervical cat scratch disease lymphadenitis in a patient with immunoglobulin m antibodies to toxoplasma gondii. | we report on a young patient with chronic cervical lymphadenopathy and serological and histological evidence for infection with bartonella henselae and toxoplasma gondii. serological follow-up studies, including testing for avidity of toxoplasma-specific immunoglobulin g antibodies, assisted in the determination of the cause of the acute lymphadenitis. our results suggest that the clinical symptoms were most likely due to cat scratch disease rather than to acute toxoplasmosis. | 2002 | 11874902 |
| genomic variation of bartonella henselae strains detected in lymph nodes of patients with cat scratch disease. | bartonella henselae is the primary agent of cat scratch disease (csd). in order to study the genetic variation of b. henselae and the correlation of the various genotypes with epidemiological and clinical findings, two seminested, groel- and pap31-based pcr assays were carried out with specimens from 273 patients. amplicons were sequenced to determine the genotype of the causative bartonella species. compared to our reference intergenic spacer region-based pcr, the groel- and pap31-based assays ... | 2002 | 11880432 |
| [adult, afebrile patient with rapidly growing tumor of the upper arm: bartonella henselae as the etiology]. | | 2002 | 11885017 |
| cat-scratch disease in an immunocompromised host. | the main causative agents of cat-scratch disease are bartonella henselae, tiny, gram-negative bacilli. the disease usually has a benign course with the development of a papule at the inoculation site, followed by regional lymphadenopathy. in most cases, complete resolution occurs, but in immunocompromised hosts, the course of the disease can be aggravated. | 2002 | 11887039 |
| [a case of cat scratch disease with encephalopathy]. | we report an atypical case of cat scratch disease (csd), accompanied with encephalopathy that is a rare complication of csd. a 17-year old man consulted a doctor for his right axillary lymphadenopathy. the history of his contact with cats and the sign of lymphnode swelling and fever suggested a suspect of cat scratch disease. administration of ampicillin improved his clinical symptoms, but a few days later he suddenly fell into coma after an episode of convulsion. the ct scan of the brain and la ... | 2002 | 11904996 |
| cat-scratch disease in children--texas, september 2000-august 2001. | cat-scratch disease (csd), a bacterial infection caused by bartonella henselae, has emerged as a relatively common and occasionally serious zoonotic disease among children and adults. to illustrate the spectrum of clinical manifestations of csd observed during a 1-year period, texas children's hospital (tch) in houston reviewed the medical records of 32 children evaluated at tch during september 2000-august 2001 whose antibody titers indicated recent bartonella infection. this report summarizes ... | 2002 | 11922191 |
| a case report of bacillary angiomatosis in a patient infected with human immunodeficiency virus. | a man infected with human immunodeficiency virus (hiv) presented with a few-month history of an enlarging friable growth on the medial area of the left foot and a one-week history of bilateral lower extremity edema. clinical and histologic examination led to a diagnosis of bacillary angiomatosis, and the patient responded to antibiotic therapy we provide an overview of bacillary angiomatosis, a rare disorder that affects immunocompromised patients with cd4 cell counts less than 100/microl. | 2002 | 11926335 |
| severe thrombocytopenic purpura as a complication of cat scratch disease. | | 2002 | 11931328 |
| prevalence of bartonella infection in domestic cats in denmark. | whole blood and serum from 93 cats (44 pets and 49 shelter/stray cats) from denmark were tested for the presence of feline bartonella species by culture and for the presence of bartonella antibodies by serology. bartonella henselae was isolated from 21 (22.6%) cats. bacteremia prevalence was not statistically different between shelter/stray cats (13/49, 26.5%) and pet cats (8/44, 18.2%), but varied widely by geographical origin of the cats, even after stratification for cat origin or age (p < 0. ... | 2002 | 11944808 |
| a heat-stable component of bartonella henselae upregulates intercellular adhesion molecule-1 expression on vascular endothelial cells. | bartonella henselae upregulated the expression of intercellular adhesion molecule-1 (icam-1) on human umbilical vein endothelial cells (huvecs). the induction level of icam-1 depended on the inoculation bacterial dose. icam-1 expression began increasing 4 h after infection and reached a sustained peak beginning at 12 h after b. henselae infection; this time course was similar to that of lipopolysaccharide (lps) of escherichia coli. the stimulatory effect was abolished when live b. henselae were ... | 2002 | 11967118 |
| cat-scratch disease in children--texas, september 2000 to august 2001. | | 2002 | 11974428 |
| the global phylogeny of glycolytic enzymes. | genes encoding the glycolytic enzymes of the facultative endocellular parasite bartonella henselae have been analyzed phylogenetically within a very large cohort of homologues from bacteria and eukaryotes. we focus on this relative of rickettsia prowazekii along with homologues from other alpha-proteobacteria to determine whether there have been systematic transfers of glycolytic genes from the presumed alpha-proteobacterial ancestor of the mitochondrion to the nucleus of the early eukaryote. th ... | 2002 | 11983902 |
| in situ detection of bartonella henselae cells. | a new in situ hybridization technique was developed for identification of bartonella henselae cells in cell suspension or in tissue sections. use of highly specific probes labeled with either fluorescein or digoxigenin allows discrimination between b. henselae and closely related b. quintana cells. no cross-hybridization with other bartonella or non-bartonella species was observed. besides its specificity it showed higher sensitivity as compared to pcr based detection methods. moreover, its appl ... | 2002 | 12005447 |
| cat scratch disease. | | 2002 | 12016189 |
| isolation of bartonella henselae from domestic cats in an italian urban area. | bartonella henselae is the causative agent of cat scratch disease (csd) in humans. cat is considered the reservoir of the bacterium. identification of bacteriemic cats is the basic tool in the prophylaxis of csd. blood samples were collected between january 1999-december 2000 from 248 domestic cats living in an urban area (reggio emilia) in northern italy and tested for bartonella henselae bacteriemia. cultural and pcr methods were used. pcr was used directly on cat blood as well as to identify ... | 2002 | 12019735 |
| inoculation with bartonella henselae followed by feline herpesvirus 1 fails to activate ocular toxoplasmosis in chronically infected cats. | infection by toxoplasma gondii is very common in cats although most remain disease free. the factors that trigger development of uveitis in some cats infected with t gondii have not been elucidated, but infection by more than one organism may be contributory. in this study, cats chronically infected with t gondii were inoculated with bartonella henselae followed by fhv-1 to test the hypothesis that immune stimulation by multiple infections will reactivate ocular toxoplasmosis. anterior uveitis a ... | 2002 | 12027509 |
| prevalence of antibodies to bartonella henselae, b. elizabethae and b. quintana in swedish domestic cats. | sera from 292 cats were analyzed by means of indirect immunofluorescence for antibodies to bartonella henselae, b. quintana and b. elizabethae. the sera were sent to the swedish national institute of veterinary medicine for health monitoring and were tested retrospectively for antibodies to bartonella. the most prevalent antibodies (25%) reacted with the b. elizabethae antigen. cats with such antibodies were older than those without antibodies. the prevalence of antibodies to b. elizabethae was ... | 2002 | 12030392 |
| from the centers for disease control and prevention. cat-scratch disease in children--texas, september 2000-august 2001. | | 2002 | 12035788 |
| genotypic characteristics of two serotypes of bartonella henselae. | the study of 16s rrna gene sequences of all isolates of bartonella henselae obtained in our laboratory and others from human patients or cats has revealed two genotypes according to the sequence of the 16s rrna gene. two isolates of these genotypes have previously been related to two different serotypes, and lack of cross-protection of the two serotypes has been demonstrated in cats. we investigated the grouping of eight strains of b. henselae on the basis of 16s ribosomal dna, 35-kda protein, p ... | 2002 | 12037055 |
| lacrimal gland involvement in kikuchi-fujimoto disease. | purpose. a 32-year-old saudi female presented with typical kikuchi-fujimoto disease, i.e., fever, cervical lymphadenitis and leukopenia, but there was also painful upper eyelid swelling with pain on upgaze. methods. a connective tissue disease and lymphoma workup were unremarkable, as were antibody titers to apifia felis and bartonella henselae. results. orbital computed tomography showed significant lacrimal gland enlargement. cervical node biopsy revealed necrotizing lymphadenitis. conclusion. ... | 1998 | 12048711 |
| fatal meningitis and encephalitis due to bartonella henselae bacteria. | bacterial infection due to bartonella henselae commonly develops in children and young adults following cat/dog contacts and/or cat/dog scratches. regional lymphadenopathy is its most common clinical expression. however, encephalitis and parinaud's syndrome (oculoglandular syndrome) have also been reported as has systemic illness. a review of the international literature in all languages revealed no fatal complications in immunocompetent hosts. a four-year-old white child with no underlying illn ... | 2002 | 12051353 |
| low prevalence of bartonella henselae infections in norwegian domestic and feral cats. | bartonella henselae is the causative agent of cat scratch disease (csd). this clinical entity is very rarely encountered in human medical practice in norway. b. henselae infections including bacteraemia in cats have been frequently reported. the objective of the present study was to investigate the seroprevalence rate and the degree of b. henselae bacteraemia in norwegian domestic and feral cats. one hundred cats investigated at a small animal veterinary practice in the middle of norway were inc ... | 2002 | 12076266 |
| [treatment of bite wounds and cat-scratch disease]. | although rabies is the most serious consequence of animal bite injuries, in urban rabies-free countries the risk of rabies is far lower than the risk of bacterial infections of the wound. the most frequent etiologic cause of the wound infections after dog bites is pasteurella multocida, as well as in the case of bites by cats, after which cat-scratch disease may also develop, its main cause being bartonella henselae. all bite injuries must be carefully cleaned and disinfected; it is necessary to ... | 2001 | 12078126 |
| lack of correlation between bartonella dna detection within fleas, serological results, and results of blood culture in a bartonella-infected stray cat population. | to correlate the presence of different bartonella species in the blood of a stray cat population trapped on a french military base with specific antibodies and species detected in cat fleas. | 2002 | 12084102 |
| gross hematuria in a young child with axillary lymphadenopathy. | | 2002 | 12086202 |
| do plant and human pathogens have a common pathogenicity strategy? | recently, a novel 'two-step' model of pathogenicity has been described that suggests host-cell-derived vasculoproliferative factors play a crucial role in the pathogenesis of bacillary angiomatosis, a disease caused by the human pathogenic bacterium bartonella henselae. the resulting proliferation of endothelial cells could be interpreted as bacterial pathogens triggering the promotion of their own habitat: the host cell. similar disease mechanisms are well known in the plant pathogen agrobacter ... | 2002 | 12088662 |
| [bartonella infection]. | bartonella species have been recently recognized as an important human pathogen associated with a wide spectrum of diseases. four members of the genus are known to cause human infection: bartonella baciliformis, b. henselae, b. quintana and b. elizabethae. b. baciliformis, the first identified bartonella species, is the agent of two disease entities, oroya fever and verruga peruana., b. henselae and b. quintana are two species involved in producing bacteremic syndromes (relapsing fever, trench f ... | 2001 | 12092178 |
| value of microimmunofluorescence for diagnosis and follow-up of bartonella endocarditis. | bartonella endocarditis is a disease of emerging importance that causes serious complications and high rates of mortality. due to the fastidious nature of bartonella species and their high degrees of antibiotic susceptibility, cultures of clinical samples most often remain sterile and valvular biopsy specimens, the best specimens for pcr amplification, are seldom available. therefore, serology appears to be the easiest diagnostic tool. in order to determine the best cutoff value for serology and ... | 2002 | 12093675 |
| induction of a potential paracrine angiogenic loop between human thp-1 macrophages and human microvascular endothelial cells during bartonella henselae infection. | bartonella henselae is responsible for various disease syndromes that loosely correlate with the immune status of the host. in the immunocompromised individual, b. henselae-induced angiogenesis, or bacillary angiomatosis, is characterized by vascular proliferative lesions similar to those in kaposi's sarcoma. we hypothesize that b. henselae-mediated interaction with immune cells, namely, macrophages, induces potential angiogenic growth factors and cytokines which contribute in a paracrine manner ... | 2002 | 12117969 |
| positive polymerase chain reaction and histology with borderline serology in parinaud's oculoglandular syndrome. | to report a case of parinaud's oculoglandular syndrome (pos) in which, despite a borderline serology, polymerase chain reaction (pcr) testing for a conjunctival biopsy was positive for bartonella henselae, a source of cat-scratch disease. a steiner silver stain demonstrated the organism. | 2002 | 12131048 |
| bacillary splenitis (bartonella henselae) during immune restoration in an hiv-infected patient. | | 2002 | 12131223 |
| characterization of the first bartonella henselae strain isolated from a cat in italy. | bartonella henselae has been identified and characterized for the first time in italy. a strain, designed pavia-1, was isolated from the blood of a cat whose owner developed cat scratch disease (csd). pavia-1 and two american b. henselae strains (houston-1, atcc 49882, type i and strain 269608, uc davis, type ii) were compared by whole-cell fatty analysis (cfa), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) for protein profiles, western immunoblotting (wb) for reactivity w ... | 2002 | 12135236 |
| fourteen-year seroepidemiological study of zoonoses in a greek village. | a seroepidemiological study carried out in a high-risk village in crete in 1985-1987 and 1998 showed that although the awareness of the people concerning zoonoses had increased during this period, the situation did not improve: there was a significant increase of the spread of seroprevalence in time and space of coxiella burnetii, rickettsia typhi, brucella sp., and entamoeba histolytica. toxoplasma gondii, rickettsia conorii, borrelia burgdorferi, echinococcus granulosus, leishmania sp., and fa ... | 2002 | 12135274 |
| serological investigation of bartonella henselae infections in clinically cat-scratch disease-suspected patients, patients with cardiovascular diseases, and healthy veterinary students in japan. | seroprevalence of bartonella henselae was investigated in japan in 48 individuals clinically suspected of having cat-scratch disease (csd), 159 patients with cardiovascular diseases, and 129 healthy veterinary students. of 48 csd-suspected patients examined, 19 (39.6%) were positive for b. henselae-igg and 4 (8.3%) for b. henselae-igm. of 159 patients with cardiovascular diseases, 5 (3.1%) were positive for b. henselae-igg. in healthy veterinary students, 14 of 129 (10.9%) were positive for b. h ... | 2002 | 12139390 |
| acute disseminated encephalomyelitis in children. | to describe the epidemiologic, clinical, neuroimaging, and laboratory features; treatment; and outcome in a cohort of children with acute disseminated encephalomyelitis (adem). | 2002 | 12165620 |
| a new type iv secretion system promotes conjugal transfer in agrobacterium tumefaciens. | two dna transfer systems encoded by the tumor-inducing (ti) plasmid have been previously identified in agrobacterium tumefaciens. the virb operon is required for the transfer of transferred dna to the plant host, and the trb system encodes functions required for the conjugal transfer of the ti plasmid between cells of agrobacterium. recent availability of the genome sequence of agrobacterium allowed us to identify a third system that is most similar to the virb type iv secretion system of barton ... | 2002 | 12169609 |
| cat scratch disease. survey on the presence of bartonella henselae among cats of tuscany. | to verify the presence of bartonella henselae-infection in cats living in tuscany (central italy) serological and bacteriological surveys were carried out. the blood serum samples of 427 cats, 254 living in private houses and gardens and 173 in public or private catteries, were tested for anti-b. henselae antibodies by indirect immunofluorescence assay (ifa). among these samples, 35 were examined by ifa to detect antibodies against bartonella quintana. bacteriological examinations were performed ... | 2002 | 12173772 |
| ultrastructural changes in a standard strain of bartonella henselae after passages through balb/can mice. | human bartonelloses are a group of illnesses of poorly understood pathogenesis. bartonella henselae is one of the most studied bacterium of its genus. the objective of this study was to observe whether passages of these bacteria, in vivo, would determine ultrastructural changes in them. for this purpose, isogenic mice were inoculated with a standard strain of b. henselae (i). these were initially retrieved from genetically immunodeficient animals (ii) and then inoculated in immunocompetent ones. ... | 2002 | 12184374 |
| an uncommon presentation of bartonella-associated neuroretinitis. | this article documents a case of neuroretinitis initially presenting with ocular pain, 20/20 visual acuities, optic disc edema, and macular serous detachment without macular star formation in the absence of a history of exposure to pets or cats or symptoms suggestive of bartonella infection. this initial clinical presentation appeared unilateral, but later became bilateral. | 2002 | 12199539 |
| role of cat-scratch disease in lymphadenopathy in the head and neck. | bartonella henselae is the causative agent of cat-scratch disease (csd), which usually manifests as acute regional lymphadenopathy. the causes of cervical lymphadenopathy, with special regard to csd, were investigated in a study of 454 patients who presented with unclear masses in the head and neck from january 1997 through january 2001. sixty-one patients (13.4%) experienced csd; 54 (11.9%) had primary lymphadenopathy due to other infectious agents, and 41 (9.0%) had lymphadenopathy that occurr ... | 2002 | 12203159 |
| comparison of in-house and commercial slides for detection by immunofluorescence of immunoglobulins g and m against bartonella henselae and bartonella quintana. | we compared the sensitivities and specificities of indirect fluorescent antibody tests developed in our laboratory and commercially available from focus technologies (ft; formerly mrl diagnostic) for detection of serum antibodies to bartonella spp. serum samples tested were from patients with culture- or pcr-confirmed bartonella quintana or b. henselae infections causing cat scratch disease (csd), chronic bacteremia, or endocarditis. at a cutoff titer of 64, the ft test had higher sensitivity th ... | 2002 | 12204950 |
| prevalence of bartonella species causing bacteraemia in domesticated and companion animals in the united kingdom. | between october 1999 and february 2000, 691 blood samples examined routinely for either haematological or virological assessment were screened by culture for the presence of bartonella species. they came from 615 animals: 360 cats, 211 dogs, 27 horses, 16 cattle and a gorilla. the samples were incubated for long periods on 10 per cent horse blood agar at 37 degrees c in an atmosphere containing 5 per cent carbon dioxide. isolates were obtained from 35 samples from 34 (9.4 per cent) of the cats, ... | 2002 | 12219899 |
| cat scratch disease and acute rejection after pediatric renal transplantation. | cat scratch disease (csd) can lead to unexplained fever, generalized lymphadenopathy and organomegaly in immunocompetent individuals. csd has rarely been reported in immunocompromised transplant recipients, where its clinical features would mimic the more common post-transplant lymphoproliferative disease (ptld). we report three cases of csd seen recently in children who had received prior kidney transplants. the three children were between 7 and 9 yr old, and had received kidney transplants 2-4 ... | 2002 | 12234274 |