| in vitro antifungal activity of naftifine hydrochloride against dermatophytes. | the incidence of superficial dermatophytoses is high in developed countries, and there remains a need for effective topical antifungals. in this study, we evaluated the in vitro antifungal activity of naftifine hydrochloride, the active ingredient in naftifine hydrochloride cream and gel 1% and 2%, against dermatophytes. the mics and minimum fungicidal concentrations (mfcs) of naftifine hydrochloride against 350 clinical strains, including trichophyton rubrum, t. mentagrophytes, t. tonsurans, ep ... | 2013 | 23817365 |
| molecular analysis of dermatophytes suggests spread of infection among household members. | dermatophyte infection from the same strains may be an important route for transmission of dermatophytoses within a household. in this study, we used molecular methods to identify dermatophytes in members of dermatophyte-infected households and evaluated variables associated with the spread of infection. fungal species were identified by polymerase chain reaction (pcr) using primers targeting the internal transcribed spacer (its) regions (its1 and its4). for strain differentiation, fungal dna wa ... | 2013 | 23772429 |
| public health significance of dermatophytes in ismailia and port said provinces, egypt. | [corrected] dermatophytes are common in both developed and developing countries, the species involved and the resulting clinical entities vary geographically. | 2013 | 23760076 |
| optimization of pcr-rflp directly from the skin and nails in cases of dermatophytosis, targeting the its and the 18s ribosomal dna regions. | a pan fungal primer targeting the internal transcribed spacer (its) region and optimization of pcr-rflp using a dermatophyte specific primer targeted the 18s ribosomal dna (rdna) region were performed for the identification of dermatophyte species and strains directly from clinical specimens. | 2013 | 23730638 |
| evaluation of bioactivities of chlorokojic acid derivatives against dermatophytes couplet with cytotoxicity. | in an attempt to find novel antifungal agents with improved activity, a series of compounds bearing 6-chloromethyl-3-hydroxy-2-substituted 4h-pyran-4-one moiety were synthesized and examined for their cytotoxic evaluation and antifungal activities against both standard and isolated dermatophytic fungal species microsporum gypseum, trichophyton mentagrophytes var. erinacei and epidermophyton floccosum. | 2013 | 23664872 |
| the use of albino adult hair and blond prepubertal hair yields equivalent results in an in vitro hair perforation test to differentiate between different dermatophytic fungi. | an in vitro hair perforation test is used to differentiate isolates of trichophyton mentagrophytes and trichophyton rubrum complexes because morphological criteria are insufficient. here, we performed in vitro hair perforation tests using blond prepubertal hair and albino adult hair to determine whether they differentiate between fungal species. we tested 43 well-characterized dermatophyte strains, arthroderma spp. [n = 4], epidermophyton floccosum [n = 1], microsporum spp. [n = 8], and trichoph ... | 2013 | 23591622 |
| [molecular biological detection of dermatophytes in clinical samples when onychomycosis or tinea pedis is suspected. a prospective study comparing conventional dermatomycological diagnostics and polymerase chain reaction]. | the prevalence of onychomycosis is rising worldwide. before starting antifungal treatment, an exact mycological diagnosis should be obtained. the current laboratory diagnosis of dermatomycoses is based on the detection of the causative agent by microscopy and culture. these conventional diagnostic methods for fungal infections often are not the best solution because they are time-consuming, cultures are false-negative and direct examination identifies non-vital structures which cannot be used fo ... | 2013 | 23532505 |
| inhibitory effect of linalool-rich essential oil from lippia alba on the peptidase and keratinase activities of dermatophytes. | abstract lippia alba (miller) n.e. brown is an aromatic plant known locally as "erva-cidreira-do-campo" that has great importance in brazilian folk medicine. the aim of our study was to evaluate the antidermatophytic potential of linalool-rich essential oil (eo) from l. alba and analyze the ability of this eo to inhibit peptidase and keratinase activities, which are important virulence factors in dermatophytes. the minimum inhibitory concentrations (mics) of l. alba eo were 39, 156 and 312 µg/ml ... | 2014 | 23323991 |
| identification of dermatophytes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | in this study we evaluated the suitability of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) for the identification of dermatophytes in diagnostic laboratories. first, a spectral database was built with 108 reference strains belonging to 18 species of the anamorphic genera epidermophyton, microsporum and trichophyton. all strains were well characterized by morphological criteria and its sequencing (gold standard). the dendrogram resulting from maldi-t ... | 2013 | 23228046 |
| [2006 epidemiological survey of dermatomycoses in japan]. | an epidemiological survey of dermatomycoses and the causative fungus flora of dermatomycoses in japan for 2006 was made on a total number of 63,029 outpatients who visited 16 dermatological clinics throughout japan. the results were as follows. 1) dermatophytosis was the most prevalent cutaneus fungal infection (7,582 cases) seen in these clinics, followed by candidiasis (842 cases) and then malassezia infections (283 cases). 2) among dermatophytoses, tinea pedis was the most frequent (4,779 cas ... | 2012 | 23149353 |
| in vitro antifungal activity of micafungin and caspofungin against dermatophytes isolated from china. | the aims of this study are to investigate the in vitro activities of micafungin and caspofungin that are two new echinocandin antifungal drugs against clinically isolated dermatophytes in china and to define mec (minimal effective concentration) as the reading endpoints of this study in accordance with (clinical and laboratory standards institute) clsi m38-a2 reference. | 2013 | 22983900 |
| epidemiology of dermatophytoses in crete, greece between 2004 and 2010. | the present work was undertaken in order to study the epidemiology of dermatophytoses in the island of crete, greece, over a 7-year period (2004-2010) and to compare the results with those reported earlier from this region and from other parts of the world. | 2012 | 22648332 |
| molecular epidemiology of dermatophytosis in tehran, iran, a clinical and microbial survey. | in the framework of a survey on dermatophytoses, 14,619 clinical specimens taken from outpatients with symptoms suggestive of tinea and referred to a medical mycology laboratory in tehran, iran, were analyzed by direct microscopy and culture. in total, 777 dermatophyte strains recovered in culture were randomly identified by a formerly established rflp analysis method based on the rdna its regions. for confirmation of species identification, 160 isolates representing the likely entire species sp ... | 2013 | 22587730 |
| dermatophytes isolated from the mosques in tokat, turkey. | dermatophytes are a group of fungi that invade keratinized tissues such as the skin, hair and nails. the aim of this study was to investigate the existence of the potential causative agents of dermatophytosis in the mosque area in tokat, turkey. thirty mosques were included in the study. a total of two hundred samples were collected from various parts of carpets and slippers in the mosques. positive cultures were obtained in 144 samples (113 from carpets, 31 from slippers). among the species iso ... | 2012 | 22576940 |
| maldi-tof mass spectrometry - a rapid method for the identification of dermatophyte species. | altogether 285 dermatophyte isolates of 21 different species - including both trichophyton rubrum and t. interdigitale, but also eight additional trichophyton species, microsporum canis and seven other microsporum species, as well as epidermophyton floccosum and arthroderma spp. - were analyzed using matrix assisted laser desorption ionization time-of-flight mass spectrometry (maldi-tof ms) and the anagnostec 'saramis' (spectral archiving and microbial identification system) software. in additio ... | 2013 | 22574631 |
| dermatophyte infections mimicking other skin diseases: a 154-person case survey of tinea atypica in the district of cagliari (italy). | although usually simple, the diagnosis of dermatophyte infection is sometimes neglected. an observational study has been realized to evaluate the role of corticosteroid exposure (tinea incognito) and of other primary characteristics of the dermatophytosis that from onset mimic other diseases and mislead an unexperienced physician. | 2012 | 22435428 |
| frequency and aetiology of dermatophytosis in children age 12 and under in the state of amazonas, brazil. | few scientific studies have evaluated dermatophytosis among children in the state of amazonas or in the greater northern region of brazil. | 2012 | 22410497 |
| inhibition of dermatophytes by the antimicrobial peptides human β-defensin-2, ribonuclease 7 and psoriasin. | previous studies have described some antibacterial effects of antimicrobial peptides (amps) expressed in human skin, but little is known about their possible activity against dermatophytes. therefore we have tested the effects of human β-defensin 2 (hbd-2), ribonuclease 7 (rnase 7) and psoriasin on the in vitro growth of four dermatophyte species. germinating conidia of trichophyton rubrum, t. mentagrophytes, microsporum canis and epidermophyton floccosum were exposed in vitro to hbd-2, rnase 7, ... | 2012 | 22332906 |
| investigation of anti-dermatophytic effects of non-steroidal anti-inflammatory drugs on trichophyton mentagrophytes and epidermophyton floccosum. | non-steroidal anti-inflammatory drugs (nsaids) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. in this study, seven of nsaids were tested against two species of skin pathogenic fungi (dermatophytes). percentage inhibition was determined for effective agents. diclofenac, aspirin and naproxen showed much more ability to inhibit dermatophytes growth. epidermophyton floccosum revealed susceptibility to mor ... | 2011 | 24250387 |
| studies on antidermatophytic activity of waste leaves of curcuma longa l. | during antidermatophytic screening of some essential oils, curcuma longa l. exhibited the strongest antifungal activity, completely inhibiting the mycelial growth of ringworm, caused by the fungi- microsporum gypseum and trichophyton mentagrophytes. the essential oil from leaves of curcuma longa was fungicidal at 2.5 μl/ml at which it tolerated heavy doses of inoculum. the fungicidal activity of the oil was thermostable up to 80 °c and self life up to 24 months in storage. the oil also showed a ... | 2010 | 23572967 |
| fungal contamination of indoor public swimming pools, ahwaz, south-west of iran. | using public swimming pools during different seasons and poor health behavior could be responsible in transmission of fungal disease through pool water and its environment. therefore, this research was conducted to investigate fungal agents of indoor public swimming pools of ahwaz, capital city of khouzestan province, south-west of iran. | 2010 | 23113031 |
| in vitro antifungal evaluation and studies on mode of action of eight selected species from the argentine flora. | twenty nine extracts belonging to eight species of the argentine flora reported as antifungal in folk medicine, were assayed for antifungal properties by using the agar dilution method, against a panel of yeasts, filamentous fungi as well as dermatophytes. nine extracts belonging to six species, exhibited a broad spectrum of activity against microsporum cants, microsporum gypseum, trichophyton mentagrophytes, trichophyton rubrum and epidermophyton floccosum, with mics ranging from 25 to 900 μg/m ... | 1998 | 23195989 |
| dermatophytosis of the scrotum, penis and lip. | a young male had tinea cruris due to epidermophyton floccosum. he had associated dermatophytosis of the scrotum, penis and upper lip from which the same species of fungus was isolated. on the lip, the lesion extended to the vermilion area (prolabium) of the lip and the term 'tinea labialis' is suggested for this condition. | 2017 | 28145332 |
| clinico mycological study of dermatophytosis in a coastal area. | clinico-mycological features of one hundred patients suffering from tinea cruris are reported. ninety two per cent are males and 79% are in the age group of 11-39 years. involvement of axillae is seen in four penile involvement in five patients. 'twenty-eight patients have tinea corporis and nine tinea vesicolor also. seventy seven patients show isolation of dernm-tophytes by culture. the commonest species of dermatophytes is trichophyron rubrum (57.1%) followed by t. mentagraphytes (31.20/o), e ... | 2017 | 28176711 |
| mycology of cutaneous fungal infections in ambajogai: a rural area. | two hundred and eithteen cases of fungal skin infections were studied. tinea cruris was most common (34.4%), followed by tinea corporis (23.8%) znd tinea pedis (21.6%). tinea versicolor (8.7%) tinea manum (4.6%) tinea ungaium (3.7%) and tinea capitis (3.2%) were also seen. the male: female ratio was 4:1. the total isolates were 117. trichophyton rubrum was the most common isolate (35%). closely followed by epidermophyton floccosum (31.6%). trichphyton mentagrophytes (17.9%), malassezia furfur (1 ... | 2017 | 28211405 |
| composition and antifungal activity of zhumeria majdae essential oil. | essential oils extracted from different plants are extensively used in perfume, beverage, and food industries and are reported to exhibit antimicrobial activities against a variety of fungi. zhumeria majdae belonging to the lamiaceae family is a rare and endemic medicinal plant species in iran, with a strong and pleasant odor. the leaves of this plant have been used for many years as an antiseptic carminative agent for the treatment of stomachache (especially in infants) and dysmenorrhea. | 2015 | 28680999 |
| anti-dermatophyte activity of leguminosae plants from southern brazil with emphasis on mimosa pigra (leguminosae). | intensive prophylactic use of antifungals leads to the increase of drug resistance and the need for new and more effective treatments are real. plants from leguminosae family are rich in flavonoids, for which numerous biological activities have been described, including antifungal effects. | 2017 | 28822705 |
| dermatophytosis and dermatomycosis in pune. | dermatophytosis and dermatomycosis in patients reporting to command hospital (sc) were studied over a period of 3 years. a total of 126 cases were investigated. commonest clinical diagnosis was tinea corporis (39.68%) followed by onychomycosis (20.63%). some patients had infections of multiple sites. direct examination under koh and dimethyl sulfoxide (dmso) revealed fungal elements in 43 (34.12%) cases. fungi were isolated from 44 (34.92%) cases. commonly isolated fungi were candida albicans 11 ... | 1999 | 28775555 |
| distribution of species of dermatophyte among patients at a dermatology centre of nghean province, vietnam, 2015-2016. | vietnam is a tropical country so fungal diseases including dermatophytosis may be prevalent, but epidemiological profiles of agents responsible for the infection have rarely been reported. | 2017 | 28831770 |
| diagnosis of dermatophytosis by conventional methods and comparatative analysis of sabouraud dextrose agar and dermatophyte test medium for isolation of dermatophytes. | dermatophytosis is a fungal disease which ranked as one of the most common cutaneous condition in all over the world. the aim of this cross sectional observational study is to identify the etiological agent of dermatophytosis and comparison of sabouraud dextrose agar (sda) and dermatophyte test medium (dtm) for the primary isolation of dermatophytes among the clinically suspected cases of dermatophytosis from the outpatient department of dermatology and venereology, mymensingh medical college ho ... | 2017 | 28588164 |
| a study on etiologic agents and clinical manifestations of dermatophytosis in yazd, iran. | dermatophytosis is one of the most common infections of skin, hair, and nails, caused by a group of keratinophilic fungi known as dermatophytes. species identification of these fungi is of great significance from epidemiological and therapeutic points of view. the objective of the present study was to investigate dermatophytosis and its causative agents in patients, referring to the central mycology laboratory of yazd university of medical sciences, yazd, iran. | 2015 | 28681000 |