consensus multivariate methods in gas chromatography mass spectrometry and denaturing gradient gel electrophoresis: mhc-congenic and other strains of mice can be classified according to the profiles of volatiles and microflora in their scent-marks. | house mice (mus domesticus) communicate using scent-marks, and the chemical and microbial composition of these 'extended phenotypes' are both influenced by genetics. this study examined how the genes of the major histocompatibility complex (mhc) and background genes influence the volatile compounds (analysed with gas chromatography mass spectrometry or gc/ms) and microbial communities (analysed using denaturating gradient gel electrophoresis or dgge) in scent-marks produced by congenic strains o ... | 2009 | 19082183 |
inference of historical changes in migration rate from the lengths of migrant tracts. | after migrant chromosomes enter a population, they are progressively sliced into smaller pieces by recombination. therefore, the length distribution of "migrant tracts" (chromosome segments with recent migrant ancestry) contains information about historical patterns of migration. here we introduce a theoretical framework describing the migrant tract length distribution and propose a likelihood inference method to test demographic hypotheses and estimate parameters related to a historical change ... | 2009 | 19087958 |
selection on cis-regulatory variation at b4galnt2 and its influence on von willebrand factor in house mice. | the riiis/j inbred mouse strain is a model for type 1 von willebrand disease (vwd), a common human bleeding disorder. low von willebrand factor (vwf) levels in riiis/j are due to a regulatory mutation, mvwf1, which directs a tissue-specific switch in expression of a glycosyltransferase, b4galnt2, from intestine to blood vessel. we recently found that mvwf1 lies on a founder allele common among laboratory mouse strains. to investigate the evolutionary forces operating at b4galnt2, we conducted a ... | 2009 | 19088380 |
glycogen storage and muscle glucose transporters (glut-4) of mice selectively bred for high voluntary wheel running. | to examine the evolution of endurance-exercise behaviour, we have selectively bred four replicate lines of laboratory mice (mus domesticus) for high voluntary wheel running (;high runner' or hr lines), while also maintaining four non-selected control (c) lines. by generation 16, hr mice ran approximately 2.7-fold more than c mice, mainly by running faster (especially in females), a differential maintained through subsequent generations, suggesting an evolutionary limit of unknown origin. we hypo ... | 2009 | 19112143 |
inferring the history of speciation in house mice from autosomal, x-linked, y-linked and mitochondrial genes. | patterns of genetic differentiation among taxa at early stages of divergence provide an opportunity to make inferences about the history of speciation. here, we conduct a survey of dna-sequence polymorphism and divergence at loci on the autosomes, x chromosome, y chromosome and mitochondrial dna in samples of mus domesticus, m. musculus and m. castaneus. we analyzed our data under a divergence with gene flow model and estimate that the effective population size of m. castaneus is 200,000-400,000 ... | 2008 | 19121002 |
polymorphism in hybrid male sterility in wild-derived mus musculus musculus strains on proximal chromosome 17. | the hybrid sterility-1 (hst1) locus at chr 17 causes male sterility in crosses between the house mouse subspecies mus musculus domesticus (mmd) and m. m. musculus (mmm). this locus has been defined by its polymorphic variants in two laboratory strains (mmd genome) when mated to pwd/ph mice (mmm genome): c57bl/10 (carrying the sterile allele) and c3h (fertile allele). the occurrence of sterile and/or fertile (wild mmm x c57bl)f1 males is evidence that polymorphism for this trait also exists in na ... | 2009 | 19123034 |
effects of parity on pelvic size and shape dimorphism in mus. | the pelvis is a sexually dimorphic structure and although the causes of that dimorphism have long been studied, relatively little is known regarding the effects of partuitive events on the magnitude of that dimorphism. here, we use a sample of mus musculus domesticus to contrast dimorphism in body length and os coxae size and shape between males and parous and nulliparous females. we also test for correlations between relative litter size (l/m) and relative offspring size (o/m) with body length ... | 2009 | 19123249 |
reduction of type iib myosin and iib fibers in tibialis anterior muscle of mini-muscle mice from high-activity lines. | selective breeding of laboratory house mice (mus domesticus) for high voluntary wheel running has generated four replicate lines that show an almost threefold increase in daily wheel-running distances as compared with four nonselected control lines. an unusual hindlimb "mini-muscle" phenotype (small muscles, increased mitochondrial enzyme levels, disorganized fiber distribution) has increased in frequency in two of the four replicate selected lines. the gene of major effect that accounts for thi ... | 2009 | 19177556 |
quantitative variation of line-1 sequences in five species and three subspecies of the subgenus mus and in five robertsonian races of mus musculus domesticus. | the quantitative variation of a conserved region of the line-1 orf2 sequence was determined in eight species and subspecies of the subgenus mus (m. m. domesticus, m. m. musculus, m. m. castaneus, m. spicilegus, m. spretus, m. cervicolor, m. cookii, m. caroli) and five robertsonian races of m. m. domesticus. no differences in line-1 orf2 content were found between all acrocentric or robertsonian chromosome races, whereas the quantitative variation of the line-1 orf2 sequences detected among the e ... | 2009 | 19184476 |
lines of mice with chronically elevated baseline corticosterone levels are more susceptible to a parasitic nematode infection. | chronically elevated circulating plasma glucocorticoid concentrations can have suppressive effects on immune function in mammals. house mice (mus domesticus) that have been selectively bred for high voluntary wheel running exhibit chronically elevated (two-fold, on average) plasma corticosterone (cort) levels and hence are an interesting model to study possible glucocorticoid-induced immune suppression. as an initial test of their immunocompetence, we compared the four replicate high runner (hr) ... | 2009 | 19223159 |
efficient production of androgenetic embryos by round spermatid injection. | mammalian androgenetic embryos can be produced by pronuclear exchange of fertilized oocytes or by dispermic in vitro fertilization of enucleated oocytes. here, we report a new technique for producing mouse androgenetic embryos by injection of two round spermatid nuclei into oocytes, followed by female chromosome removal. we found that injection of round spermatids resulted in high rates of oocyte survival (88%). androgenetic embryos thus produced developed into mid-gestation fetuses at various r ... | 2009 | 19241381 |
receiving behaviour is sensitive to risks from eavesdropping predators. | conspicuous signals may attract both intended receivers as well as unintended receivers such as predators. however, signalling individuals are not the only ones at risk when communicating, as the intended receiver may encounter eavesdropping predators that are attracted to the same signals. here, we show that the house mouse (mus domesticus) behaviourally responds to social signals (scents) as though receiving carries a risk of predation. we presented mice with their own scents (low social benef ... | 2009 | 19363623 |
comparison of urinary scents of two related mouse species, mus spicilegus and mus domesticus. | whereas the house mouse (mus domesticus) has been studied extensively in terms of physiology/behavior and pheromonal attributes, the evolutionarily related mound-building mouse (mus spicilegus) has received attention only recently due to its divergent behavioral traits related to olfaction. to date, no chemical studies on urinary volatile compounds have been performed on m. spicilegus. the rationale for our investigations was to determine if there are differences in urinary volatiles of intact a ... | 2009 | 19390894 |
population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. | toxicogenomic studies are increasingly used to uncover potential biomarkers of adverse health events, enrich chemical risk assessment, and to facilitate proper identification and treatment of persons susceptible to toxicity. current approaches to biomarker discovery through gene expression profiling usually utilize a single or few strains of rodents, limiting the ability to detect biomarkers that may represent the wide range of toxicity responses typically observed in genetically heterogeneous h ... | 2009 | 19420014 |
proteomics and comparative genomic investigations reveal heterogeneity in evolutionary rate of male reproductive proteins in mice (mus domesticus). | male reproductive fitness is strongly affected by seminal fluid. in addition to interacting with the female environment, seminal fluid mediates important physiological characteristics of sperm, including capacitation and motility. in mammals, the male reproductive tract shows a striking degree of compartmentalization, with at least six distinct tissue types contributing material that is combined with sperm in an ejaculate. although studies of whole ejaculates have been undertaken in some species ... | 2009 | 19420050 |
effects of aging on mouse tongue epithelium focusing on cell proliferation rate and morphological aspects. | the aim of this study was to investigate cell proliferation rate and certain morphological features of mouse epithelium as aging progresses. tongue biopsies were performed on female mice (mus domesticus domesticus) at 2, 8, 14 and 20 months of age as indicative of adolescence, adulthood, early senescence and senescence, respectively. histological sections of tongue were stained with hematoxylin-eosin and subjected to silver staining for active nucleolar organizer region counting. cell proliferat ... | 2008 | 19420881 |
mandible shape in hybrid mice. | hybridisation between closely related species is frequently seen as retarding evolutionary divergence and can also promote it by creating novel phenotypes due to new genetic combinations and developmental interactions. we therefore investigated how hybridisation affects the shape of the mouse mandible, a well-known feature in evo-devo studies. parental groups corresponded to two strains of the european mouse sub-species mus musculus domesticus and mus musculus musculus. parents and hybrids were ... | 2009 | 19504055 |
sexual selection and the rodent baculum: an intraspecific study in the house mouse (mus musculus domesticus). | the rapid divergence of genitalia is a pervasive trend in animal evolution, thought to be due to the action of sexual selection. to test predictions from the sexual selection hypothesis, we here report data on the allometry, variation, plasticity and condition dependence of baculum morphology in the house mouse (mus musculus domesticus). we find that that baculum size: (a) exhibits no consistent pattern of allometric scaling (baculum size being in most cases unrelated to body size), (b) exhibits ... | 2010 | 19597945 |
locomotor trade-offs in mice selectively bred for high voluntary wheel running. | we investigated sprint performance and running economy of a unique ;mini-muscle' phenotype that evolved in response to selection for high voluntary wheel running in laboratory mice (mus domesticus). mice from four replicate selected (s) lines run nearly three times as far per day as four control lines. the mini-muscle phenotype, resulting from an initially rare autosomal recessive allele, has been favoured by the selection protocol, becoming fixed in one of the two s lines in which it occurred. ... | 2009 | 19648406 |
evolution of duplicated beta-globin genes and the structural basis of hemoglobin isoform differentiation in mus. | the functional diversification of multigene families may be strongly influenced by mechanisms of concerted evolution such as interparalog gene conversion. the beta-globin gene family of house mice (genus mus) represents an especially promising system for evaluating the effects of gene conversion on the functional divergence of duplicated genes. whereas the majority of mammalian species possess tandemly duplicated copies of the adult beta-globin gene that are identical in sequence, natural popula ... | 2009 | 19675095 |
molecular insights into the colonization and chromosomal diversification of madeiran house mice. | the colonization history of madeiran house mice was investigated by analysing the complete mitochondrial (mt) d-loop sequences of 156 mice from the island of madeira and mainland portugal, extending on previous studies. the numbers of mtdna haplotypes from madeira and mainland portugal were substantially increased (17 and 14 new haplotypes respectively), and phylogenetic analysis confirmed the previously reported link between the madeiran archipelago and northern europe. sequence analysis reveal ... | 2009 | 19754514 |
developmental constraints revealed by co-variation within and among molar rows in two murine rodents. | morphological integration corresponds to interdependency between characters that can arise from several causes. proximal causes of integration include that different phenotypic features may share common genetic sets and/or interact during their development. ultimate causes may be the prolonged effect of selection favoring integration of functionally interacting characters, achieved by the molding of these proximal causes. strong and direct interactions among successive teeth of a molar row are p ... | 2009 | 19754715 |
deep short-read sequencing of chromosome 17 from the mouse strains a/j and cast/ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels. | genome sequences are essential tools for comparative and mutational analyses. here we present the short read sequence of mouse chromosome 17 from the mus musculus domesticus derived strain a/j, and the mus musculus castaneus derived strain cast/ei. we describe approaches for the accurate identification of nucleotide and structural variation in the genomes of vertebrate experimental organisms, and show how these techniques can be applied to help prioritize candidate genes within quantitative trai ... | 2009 | 19825173 |
oestrous females investigate the unfamiliar male more than the familiar male in both commensal and non-commensal populations of house mice. | we studied female preferences for familiar and unfamiliar males. the subjects were laboratory-born house mice: (1) non-commensal mus musculus domesticus from the eastern part of syria along the euphrates river; and (2) commensal m. m. musculus from the czech republic. pair-choice preference tests have revealed that oestrous females of both populations sniffed towards unfamiliar males more than familiar males. in the case of females exhibiting postpartum oestrus, this preference was less pronounc ... | 2010 | 19850114 |
new metacentric population of the house mouse (mus musculus domesticus) found in valchiavenna, northern italy. | although the standard karyotype of the western house mouse (mus musculus domesticus) consists entirely of telocentric chromosomes, there are over 100 populations across western europe and north africa characterized by different sets of metacentrics formed by robertsonian fusions and whole-arm reciprocal translocations. here we report the discovery of a new metacentric population from valchiavenna, northern italy, that we have named the 'lower valchiavenna population' (abbreviated as ilvc). this ... | 2009 | 19864888 |
interacting effects of predation risk and signal patchiness on activity and communication in house mice. | 1. social signalling can be risky when signals are open to exploitation by eavesdropping predators. unlike other signal modalities, olfactory signals cannot be 'switched off' in the presence of an eavesdropping predator, leaving receivers of scent signals at an increased risk of predation long after the signaller has moved on. yet individuals of some olfactorily communicating species appear unwilling to forego the receiving of signals under an increased risk of predation. foraging theory predict ... | 2010 | 19941627 |
novel obp genes similar to hamster aphrodisin in the bank vole, myodes glareolus. | chemical communication in mammals involves globular lipocalins that protect and transport pheromones during their passage out of the body. efficient communication via this protein - pheromone complex is essential for triggering multiple responses including aggression, mate choice, copulatory behaviour, and onset and synchronization of oestrus. the roles of lipocalins in communication were studied in many organisms and especially in mice (i.e. mus musculus domesticus) which excrete major urinary ... | 2010 | 20085627 |
sperm midpiece length predicts sperm swimming velocity in house mice. | evolutionary biologists have argued that there should be a positive relationship between sperm size and sperm velocity, and that these traits influence a male's sperm competitiveness. however, comparative analyses investigating the evolutionary associations between sperm competition risk and sperm morphology have reported inconsistent patterns of association, and in vitro sperm competition experiments have further confused the issue; in some species, males with longer sperm achieve more competit ... | 2010 | 20147311 |
reduced gene flow at pericentromeric loci in a hybrid zone involving chromosomal races of the house mouse mus musculus domesticus. | the west european house mouse, mus musculus domesticus, is a particularly suitable model to investigate the role of chromosomal rearrangements in reproductive isolation. in fact, it exhibits a broad range of chromosomal polymorphism due to robertsonian (rb) fusions leading to various types of contact zones between different chromosomal races. in the present study, we analyzed a parapatric contact in central italy between the cittaducale chromosomal race (cd: 2n= 22) and the surrounding populatio ... | 2010 | 20148956 |
finding of parastrongylus cantonensis (chen, 1935) in rattus rattus in tenerife, canary islands (spain). | parastrongylus cantonensis is a parasite of murid rodents that can infect humans and cause health problems as eosinophilic meningitis. although it is endemic in south asia, the pacific islands, australia, usa, and a few caribbean islands, it has been extended to new geographical regions. in the canary islands (spain) a survey of helminths of rattus rattus, rattus norvegicus and mus musculus domesticus was carried out. furthermore, five species of molluscs were examined for nematode larvae to det ... | 2010 | 20153283 |
molecular evolution of trichuris muris isolated from different muridae hosts in europe. | a phylogeographic study was carried out of trichuris muris, nematode parasitizing murinae rodents from the muridae family, isolated from four different hosts and from different geographical regions of europe by amplification and sequencing of the its1-5.8s-its2 fragment of the ribosomal dna. t. muris was found in the apodemus sylvaticus, apodemus flavicollis, mus domesticus, and rattus rattus rodents. the molecular results confirm the presence of dna polymorphisms among t. muris isolates from eu ... | 2010 | 20473527 |
urinary volatile molecules vary in males of the 2 european subspecies of the house mouse and their hybrids. | mice recognize other mice by identifying chemicals that confer a molecular signature to urinary marks. such molecules may be involved in species recognition, and previous behavioral studies have related divergence of sexual preference between 2 subspecies of the house mouse (mus musculus musculus and mus musculus domesticus) to urinary odors. to characterize the differences between odors of males of the 2 subspecies and their first-generation offspring, the urinary volatile molecules were examin ... | 2010 | 20530376 |
a b2 sine insertion in the comt1 gene (comt1(b2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains. | catechol-o-methyltransferase (comt) is a key enzyme for dopamine catabolism and comt is a candidate gene for human psychiatric disorders. in mouse it is located on chromosome 16 in a large genomic region of extremely low variation among the classical inbred strains, with no confirmed single nucleotide polymorphisms (snps) between strains c57bl/6j and dba/2j within a 600-kb window. we found a b2 sine in the 3' untranslated region (utr) of comt1 which is present in c57bl/6j (comt1(b2i)) and other ... | 2010 | 20618449 |
xenomitochondrial mice: investigation into mitochondrial compensatory mechanisms. | xenomitochondrial mice, harboring evolutionarily divergent mus terricolor mitochondrial dna (mtdna) on a mus musculus domesticus nuclear background (b6ntac(129s6)-mt(m. terricolor)/capt; line d7), were subjected to molecular and phenotypic analyses. no overt in vivo phenotype was identified in contrast to in vitro xenomitochondrial cybrid studies. microarray analyses revealed differentially expressed genes in xenomitochondrial mice, though none were directly involved in mitochondrial function. q ... | 2011 | 20638486 |
selection against robertsonian fusions involving housekeeping genes in the house mouse: integrating data from gene expression arrays and chromosome evolution. | monobrachial homology resulting from robertsonian (rb) fusions is thought to contribute to chromosomal speciation through underdominance. given the karyotypic diversity characterizing wild house mouse populations [mus musculus domesticus, (mmu)], variation that results almost exclusively from rb fusions (diploid numbers range from 22 to 40) and possibly whole arm reciprocal translocations (warts), this organism represents an excellent model for testing hypotheses of chromosomal evolution. previo ... | 2010 | 20811941 |
genetic differentiation of the house mouse around the mediterranean basin: matrilineal footprints of early and late colonization. | the molecular signatures of the recent expansion of the western house mouse, mus musculus domesticus, around the mediterranean basin are investigated through the study of mitochondrial d-loop polymorphism on a 1313 individual dataset. when reducing the complexity of the matrilineal network to a series of haplogroups (hgs), our main results indicate that: (i) several hgs are recognized which seem to have almost simultaneously diverged from each other, confirming a recent expansion for the whole s ... | 2010 | 20880891 |
the role of wild rodents in the transmission of trypanosoma evansi infection in an endemic area of the canary islands (spain). | trypanosoma evansi was diagnosed for the first time in camels in the canary islands in 1997. several sanitary measures including treatment of infected animals were taken; however, nowadays a little area is still infected. in order to determine possible reservoirs 138 wild rodents were trapped, 64 of them in the infected farms and the remaining 74 in other areas. the captured species were rattus rattus (24), rattus norvegicus (69) and mus musculus domesticus (45). serological (catt/t. evansi), pa ... | 2010 | 20888126 |
is oxidative stress a physiological cost of reproduction? an experimental test in house mice. | investment in reproduction is costly and frequently decreases survival or future reproductive success. however, the proximate underlying causes for this are largely unknown. oxidative stress has been suggested as a cost of reproduction and several studies have demonstrated changes in antioxidants with reproductive investment. here, we test whether oxidative stress is a consequence of reproduction in female house mice (mus musculus domesticus), which have extremely high energetic demands during r ... | 2010 | 20926440 |
predators are attracted to the olfactory signals of prey. | predator attraction to prey social signals can force prey to trade-off the social imperatives to communicate against the profound effect of predation on their future fitness. these tradeoffs underlie theories on the design and evolution of conspecific signalling systems and have received much attention in visual and acoustic signalling modes. yet while most territorial mammals communicate using olfactory signals and olfactory hunting is widespread in predators, evidence for the attraction of pre ... | 2010 | 20927352 |
no postnatal maternal effect on male aggressiveness in wild-derived strains of house mice. | male aggressiveness is a complex behavior influenced by a number of genetic and non-genetic factors. traditionally, the contribution of each of these factors has been established from experiments using artificially selected strains for high/low aggressive phenotypes. however, little is known about the factors underlying aggressive behavior in natural populations. in this study, we assess the influence of genetic background vs. postnatal maternal environment using a set of cross-fostering experim ... | 2010 | 20954263 |
house mouse colonization patterns on the sub-antarctic kerguelen archipelago suggest singular primary invasions and resilience against re-invasion. | starting from western europe, the house mouse (mus musculus domesticus) has spread across the globe in historic times. however, most oceanic islands were colonized by mice only within the past 300 years. this makes them an excellent model for studying the evolutionary processes during early stages of new colonization. we have focused here on the kerguelen archipelago, located within the sub-antarctic area and compare the patterns with samples from other southern ocean islands. | 2010 | 20977744 |
norwegian house mice (mus musculus musculus/domesticus): distributions, routes of colonization and patterns of hybridization. | we investigated the distributions and routes of colonization of two commensal subspecies of house mouse in norway: mus musculus domesticus and m. m. musculus. five nuclear markers (abpa, d11 cenb2, btk, smcy and zfy2) and a morphological feature (tail length) were used to differentiate the two subspecies and assess their distributions, and mitochondrial (mt) d-loop sequences helped to elucidate their colonization history. m. m. domesticus is the more widespread of the two subspecies, occupying t ... | 2010 | 21044192 |
extraordinary sequence divergence at tsga8, an x-linked gene involved in mouse spermiogenesis. | the x chromosome plays an important role in both adaptive evolution and speciation. we used a molecular evolutionary screen of x-linked genes potentially involved in reproductive isolation in mice to identify putative targets of recurrent positive selection. we then sequenced five very rapidly evolving genes within and between several closely related species of mice in the genus mus. all five genes were involved in male reproduction and four of the genes showed evidence of recurrent positive sel ... | 2010 | 21186189 |
why is the house mouse karyotype so variable? | rates of robertsonian chromosomal evolution in the western european house mouse are about two orders of magnitude greater than for most other mammals. this has resulted in a remarkable diversity of karyotypic races in a very short period of time. recent studies are beginning to shed light on the relative contributions of mutation, drift, selection and meiotic drive in producing this pattern. | 1995 | 21237083 |
experimental evolution of sperm competitiveness in a mammal. | when females mate with multiple partners, sperm from rival males compete to fertilize the ova. studies of experimental evolution have proven the selective action of sperm competition on male reproductive traits. however, while reproductive traits may evolve in response to sperm competition, this does not necessarily provide evidence that sperm competitive ability responds to selection. indeed, a study of drosophila failed to observe divergence in sperm competitive ability of males in lines selec ... | 2011 | 21251249 |
polyandrous females benefit by producing sons that achieve high reproductive success in a competitive environment. | females of many taxa often copulate with multiple males and incite sperm competition. on the premise that males of high genetic quality are more successful in sperm competition, it has been suggested that females may benefit from polyandry by accruing 'good genes' for their offspring. laboratory studies have shown that multiple mating can increase female fitness through enhanced embryo viability, and have exposed how polyandry influences the evolution of the ejaculate. however, such studies ofte ... | 2011 | 21288948 |
genetic ecotoxicology of asbestos pollution in the house mouse mus musculus domesticus. | we tested the genetic diversity in wild mice (mus musculus domesticus) inhabiting the asbestos-polluted area as a model for the long-term mutagenic effect of asbestos. hazardous effects of deposited asbestos persist in the environment because of low rate of fiber disintegration. the upper layers of the soil in the vicinity of a former asbestos factory are nearly "saturated" with asbestos fibers and dust. natural populations of mice dwell in this area and are constantly exposed to asbestos fibers ... | 2011 | 21384142 |
managing crop damage caused by house mice (mus domesticus) in australia. | a large-scale outbreak of the house mouse populations occurs in grain growing in australia on average once every four years. high densities of mice cause major yield losses to cereal crops, and low to moderate densities of mice also cause some losses. several predictive models based on rainfall patterns have been developed to forecast mouse density. these models carry some uncertainty and the economic value of basing management actions on these models is not clear. baiting is the most commonly u ... | 2010 | 21392317 |
comparison of population estimators and indices for monitoring house mice in sorghum crops. | house mice (mus musculus domesticus schwarz & schwarz, 1943) are monitored in australia and china to track changes in mouse population densities and forecast their potential damage to cereal crops. the present study compared population indices based on the number of different mice caught and overall trap success from live-trapping with an oil card index (oc) and a tracking index (t) for monitoring mice in sorghum crops immediately before crop maturation. t was measured as the percentage of track ... | 2010 | 21392322 |
negotiating a noisy, information-rich environment in search of cryptic prey: olfactory predators need patchiness in prey cues. | 1. olfactory predator search processes differ fundamentally to those based on vision, particularly when odour cues are deposited rather than airborne or emanating from a point source. when searching for visually cryptic prey that may have moved some distance from a deposited odour cue, cue context and spatial variability are the most likely sources of information about prey location available to an olfactory predator. 2. we tested whether the house mouse (mus domesticus), a model olfactory preda ... | 2011 | 21401592 |
properties of a hybrid zone between highly distinct chromosomal races of the house mouse (mus musculus domesticus) in northern italy, and comparisons with other hybrid zones. | here we provide the first detailed description of the hybrid zone between the cremona chromosomal race of house mouse (icre; 2n = 22) and the standard all-telocentric race (40st; 2n = 40), with full karyotypes of 106 individuals from 17 localities along a transect between the 2 races to the west of lake garda in northern italy. the icre race is characterised by 9 pairs of metacentric chromosomes in a homozygous state and we use the metacentric frequency data along the transect to fit tanh metace ... | 2011 | 21540576 |
evolutionary modularity of the mouse mandible: dissecting the effect of chromosomal reorganizations and isolation by distance in a robertsonian system of mus musculus domesticus. | the mouse mandible consists of several morphogenetic units that are usually grouped into two main modules: the alveolar region and the ascending ramus. the genetic/ontogenetic modularity of the two regions implies that they might evolve independently to some extent. in particular, evolutionary modularity in quantitative traits could arise during chromosomal speciation due to lower gene flow in rearranged chromosomes. with the aim of uncovering the autonomous evolution of the mandible modules, th ... | 2011 | 21615588 |
subspecific origin and haplotype diversity in the laboratory mouse. | here we provide a genome-wide, high-resolution map of the phylogenetic origin of the genome of most extant laboratory mouse inbred strains. our analysis is based on the genotypes of wild-caught mice from three subspecies of mus musculus. we show that classical laboratory strains are derived from a few fancy mice with limited haplotype diversity. their genomes are overwhelmingly mus musculus domesticus in origin, and the remainder is mostly of japanese origin. we generated genome-wide haplotype m ... | 2011 | 21623374 |
serine/threonine-protein phosphatase 1 α levels are paralleling olfactory memory formation in the cd1 mouse. | although olfactory discrimination has already been studied in several mouse strains, data on protein levels linked to olfactory memory are limited. wild mouse strains mus musculus musculus, mus musculus domesticus and cd1 laboratory outbred mice were tested in a conditioned odor preference task and trained to discriminate between two odors, rose and lemon, by pairing one odor with a sugar reward. six hours following the final test, mice were sacrificed and olfactory bulbs (ob) were taken for gel ... | 2011 | 21647921 |
identification of ejaculated proteins in the house mouse (mus domesticus) via isotopic labeling. | seminal fluid plays an important role in successful fertilization, but knowledge of the full suite of proteins transferred from males to females during copulation is incomplete. the list of ejaculated proteins remains particularly scant in one of the best-studied mammalian systems, the house mouse (mus domesticus), where artificial ejaculation techniques have proven inadequate. here we investigate an alternative method for identifying ejaculated proteins, by isotopically labeling females with 15 ... | 2011 | 21663664 |
measures of linkage disequilibrium among neighbouring snps indicate asymmetries across the house mouse hybrid zone. | theory predicts that naturally occurring hybrid zones between genetically distinct taxa can move over space and time as a result of selection and/or demographic processes, with certain types of hybrid zones being more or less likely to move. determining whether a hybrid zone is stationary or moving has important implications for understanding evolutionary processes affecting interactions in hybrid populations. however, direct observations of hybrid zone movement are difficult to make unless the ... | 2011 | 21668551 |
different regulation of adult hippocampal neurogenesis in western house mice (mus musculus domesticus) and c57bl/6 mice. | adult hippocampal neurogenesis (ahn) of laboratory rodents is enhanced by physical exercise in a running wheel. however, little is known about modulation of ahn in wild-living rodent species. the finding that ahn cannot be modulated by voluntary exercise in wild wood mice suggests that ahn may be regulated differently under natural conditions than in laboratory adapted animals. in order to minimize genetic influences, we aimed to investigate the genetically closest wild-living relatives of labor ... | 2011 | 21803074 |
adaptive introgression of anticoagulant rodent poison resistance by hybridization between old world mice. | polymorphisms in the vitamin k 2,3-epoxide reductase subcomponent 1 (vkorc1) of house mice (mus musculus domesticus) can cause resistance to anticoagulant rodenticides such as warfarin [1-3]. here we show that resistant house mice can also originate from selection on vkorc1 polymorphisms acquired from the algerian mouse (m. spretus) through introgressive hybridization. we report on a polymorphic introgressed genomic region in european m. m. domesticus that stems from m. spretus, spans >10 mb on ... | 2011 | 21782438 |
cytokine profile in murine toxoplasmosis. | to investigate which cytokines are produced after acute infection of mice with toxoplasma gondii (t. gondii) rh strain. | 2011 | 21771408 |
the scent of senescence: sexual signalling and female preference in house mice. | sexual signals are expected to be costly to produce and maintain, thus ensuring that only males in good condition can sustain their expression at high levels. when males reach senescence they lose physiological function and condition, which could constrain their ability to invest in costly sexual signals, decreasing their attractiveness to mates. furthermore, females may have evolved mating preferences that cause avoidance of senesced males to enhance fertilization success and viability of offsp ... | 2011 | 21848973 |
distribution and genetic variation of hymenolepidid cestodes in murid rodents on the canary islands (spain). | in the canary islands there are no previous data about tapeworms (cestoda) of rodents. in order to identify the hymenolepidid species present in these hosts, a survey of 1,017 murine (349 rattus rattus, 13 rattus norvegicus and 655 mus musculus domesticus) was carried out in the whole archipelago. molecular studies based on nuclear its1 and mitochondrial coi loci were performed to confirm the identifications and to analyse the levels of genetic variation and differentiation. | 2011 | 21943096 |
male house mice evolving with post-copulatory sexual selection sire embryos with increased viability. | although mating is costly, multiple mating by females is a taxonomically widespread phenomenon. theory has suggested that polyandry may allow females to gain genetic benefits for their offspring, and thus offset the costs associated with this mating strategy. for example, the good sperm hypothesis posits that females benefit from mating multiply when genetically superior males have increased success in sperm competition and produce high quality offspring. we applied the powerful approach of expe ... | 2012 | 22011211 |
micro-evolutionary divergence patterns of mandible shapes in wild house mouse (mus musculus) populations. | insights into the micro-evolutionary patterns of morphological traits require an assessment of the natural variation of the trait within and between populations and closely related species. the mouse mandible is a particularly suitable morphological trait for such an analysis, since it has long been used as a model to study the quantitative genetics of shape. in addition, many distinct populations, sub-species and closely related species are known for the house mouse. however, morphological comp ... | 2011 | 22008647 |
production of uv-light-detectable faeces from house mice (mus musculus domesticus) after consumption of encapsulated fluorescent pigment in monitoring bait. | background: the authors investigated whether fluorescent pigment in thermoset melamine microcapsules incorporated into monitoring baits would be excreted in the faeces of wild house mice in a quantity and intensity that would be detectable by a human observer. results: experimental mice produced 24-116 uv-visible faecal pellets per 24 h; the mean dry weight was 582 mg. the number and weight of the faeces was independent of mouse sex and weight. the defecation of uv-visible faeces began at 2-3 h, ... | 2011 | 21919185 |
identification of compatibility between ooplasmic factor and sperm gene in the intersubspecific crosses involving ddk and pwk mice strains. | the ddk strain (mus musculus domesticus) of inbred mouse has a unique peculiarity known as ddk syndrome. the ddk females are mostly infertile when crossed with males of other inbred strains, while ddk males exhibit normal fertility in the reciprocal crosses, as intrastrain matings. this ddk syndrome has been demonstrated to be caused by an incompatibility system between ddk ooplasmic factor and the sperm gene of other strains owing to the ovum mutant (om) locus on mouse chromosome 11. recently, ... | 2011 | 22133683 |
isolation and gene flow: inferring the speciation history of european house mice. | inferring the history of isolation and gene flow during species differentiation can inform us on the processes underlying their formation. following their recent expansion in europe, two subspecies of the house mouse (mus musculus domesticus and mus musculus musculus) have formed a hybrid zone maintained by hybrid incompatibilities and possibly behavioural reinforcement, offering a good model of incipient speciation. we reconstruct the history of their divergence using an approximate bayesian co ... | 2011 | 22066696 |
line-1 repetitive dna probes for species-specific cloning from mus spretus and mus domesticus genomes. | mus domesticus and mus spretus mice are closely related subspecies. for genetic investigations involving hybrid mice, we have developed a set of species-specific oligonucleotide probes based on the detection of line-1 sequence differences. line-1 is a repetitive dna family whose many members are interspersed among the genes. in this study, library screening experiments were used to fully characterize the species specificity of four m. domesticus line-1 probes and three m. spretus line-1 probes. ... | 2007 | 1783397 |
descriptive kinetics of spermatogenesis in four chromosomal species of the spalax ehrenbergi superspecies in israel. | the descriptive kinetics of the spermatogenic process has been studied in the four chromosomal species of spalax ehrenbergi between november and march, the active period of reproduction. spermatid development can be subdivided into 16 steps in which the acrosome formation is clearly distinguishable and the golgi, cap and acrosomic phases are identifiable. the first 12 steps of spermiogenesis can be utilized for the definition of characteristic time-dependent relationships among different germ ce ... | 2013 | 3711819 |
burrowing behavior in wild house mice: variation within and between populations. | burrowing behavior was assessed on 120 lab-reared house mice (mus domesticus) derived from five geographic populations representing a north-south cline along the east coast of the united states. mice were placed individually into plexiglas containers filled with sand and peat moss, and their burrows were excavated 24 h later. seven measures were taken and reduced by principal-components analysis to two factors for further analysis. marked differences existed within, but not between populations, ... | 2008 | 2757595 |
16s rrna amplicon sequencing for epidemiological surveys of bacteria in wildlife. | the human impact on natural habitats is increasing the complexity of human-wildlife interactions and leading to the emergence of infectious diseases worldwide. highly successful synanthropic wildlife species, such as rodents, will undoubtedly play an increasingly important role in transmitting zoonotic diseases. we investigated the potential for recent developments in 16s rrna amplicon sequencing to facilitate the multiplexing of the large numbers of samples needed to improve our understanding o ... | 2016 | 27822541 |
leptospirosis risk increases with changes in species composition of rat populations. | rats are major reservoirs of leptospirosis and considered as a main threat to biodiversity. a recent introduction of rattus rattus to the island of futuna (western polynesia) provided the opportunity to test if a possible change in species composition of rat populations would increase the risk of leptospirosis to humans. we trapped rodents on wallis and futuna and assessed leptospira carriage in 357 rodents (rattus norvegicus, r. rattus, rattus exulans, and mus domesticus) from 2008 to 2012. whi ... | 2013 | 23535996 |
dynamics of a tularemia outbreak in a closely monitored free-roaming population of wild house mice. | infectious disease outbreaks can be devastating because of their sudden occurrence, as well as the complexity of monitoring and controlling them. outbreaks in wildlife are even more challenging to observe and describe, especially when small animals or secretive species are involved. modeling such infectious disease events is relevant to investigating their dynamics and is critical for decision makers to accomplish outbreak management. tularemia, caused by the bacterium francisella tularensis, is ... | 2015 | 26536232 |
manipulating reproductive effort leads to changes in female reproductive scheduling but not oxidative stress. | the trade-off between reproductive investment and lifespan is the single most important concept in life-history theory. a variety of sources of evidence support the existence of this trade-off, but the physiological costs of reproduction that underlie this relationship remain poorly understood. the free radical theory of ageing suggests that oxidative stress, which occurs when there is an imbalance between the production of damaging reactive oxygen species (ros) and protective antioxidants, may ... | 2013 | 24324867 |
parasites and invasions: changes in gastrointestinal helminth assemblages in invasive and native rodents in senegal. | understanding why some exotic species become widespread and abundant in their colonised range is a fundamental issue that still needs to be addressed. among many hypotheses, newly established host populations may benefit from a parasite loss ("enemy release" hypothesis) through impoverishment of their original parasite communities or reduced infection levels. moreover, the fitness of competing native hosts may be negatively affected by the acquisition of exotic taxa from invaders ("parasite spil ... | 2016 | 27670366 |
bank voles (myodes glareolus) and house mice (mus musculus musculus; m. m. domesticus) in europe are each parasitized by their own distinct species of aspiculuris (nematoda, oxyurida). | the molecular phylogeny and morphology of the oxyuroid nematode genus aspiculuris from voles and house mice has been examined. worms collected from myodes glareolus in poland, eire and the uk are identified as aspiculuris tianjinensis, previously known only from china, while worms from mus musculus from a range of locations in europe and from laboratory mice, all conformed to the description of aspiculuris tetraptera. worms from voles and house mice are not closely related and are not derived fr ... | 2015 | 26302680 |
cryptosporidium tyzzeri and cryptosporidium muris originated from wild west-european house mice (mus musculus domesticus) and east-european house mice (mus musculus musculus) are non-infectious for pigs. | three and 8 week old pigs were inoculated with cryptosporidium muris hz206 (mus musculus musculus isolate), cryptosporidium tyzerri cr2090 (m. m. musculus isolate) or c. tyzzeri cr4293 (isolate from a hybrid between mus musculus domesticus and m. m. musculus) at a dose of 1 × 10(7) oocysts per animal. inoculated pigs showed no detectable infection and no clinical symptoms of cryptosporidiosis during 30 days post infection (dpi), and no macroscopic changes were detected in the digestive tract fol ... | 2012 | 22465334 |
reaction norms of host immunity, host fitness and parasite performance in a mouse--intestinal nematode interaction. | the outcome of the encounter between a host and a parasite depends on the synergistic effects of the genetics of the two partners and the environment (sensulato) where the interaction takes place. reaction norms can depict how host and parasite traits vary across environmental ranges for different genotypes. here, we performed a large scale experiment where three strains of laboratory mice (sjl, balb/c and cba) were infected with four doses of the intestinal nematode heligmosomoides polygyrus. a ... | 2016 | 26627846 |
murine cytomegalovirus is not restricted to the house mouse mus musculus domesticus: prevalence and genetic diversity in the european house mouse hybrid zone. | murine cytomegalovirus (mcmv) is a betaherpesvirus of the house mouse, mus musculus domesticus. it is a common infectious agent of wild mice and a highly studied pathogen of the laboratory mouse. betaherpesviruses are specific to their hosts, and it is not known if other mus taxa carry mcmv or if it is restricted to m. m. domesticus. we sampled mice over a 145-km transect of bavaria-bohemia crossing a hybrid zone between m. m. domesticus and mus musculus musculus in order to investigate the occu ... | 2015 | 25320317 |
leptospira interrogans in rodents from cape verde. | leptospirosis is an important worldwide zoonotic disease that can infect both animals and humans. in most cases, leptospirosis is a nonspecific self-limiting illness, but some patients can develop a severe form with a high mortality. this study was carried out in santiago island, cape verde, in 2012-2013. a total of 62 wild rodents (rattus rattus and mus domesticus) were analyzed. the lipl32 gene, present only in pathogenic leptospira spp., was amplified by pcr, and 16 samples were positive (25. ... | 2016 | 27482622 |
evidence of lymphocytic choriomeningitis virus (lcmv) in domestic mice in gabon: risk of emergence of lcmv encephalitis in central africa. | lymphocytic choriomeningitis virus (lcmv) can cause acute fatal disease on all continents but was never detected in africa. we report the first detection of lcmv rna in a common european house mouse (mus musculus domesticus) in africa. phylogenetic analyses show a close relationship with north american strains. these findings suggest that there is a risk of the appearance of lcmv acute encephalitis cases. this is a perfect example of virus dissemination by its natural host that may have dramatic ... | 2015 | 25378495 |
isolation and characterization of a new strain of lymphocytic choriomeningitis virus from rodents in southwestern france. | a total of 821 tissue samples from rodents trapped during field campaigns organized in europe and africa were screened for the presence of arenaviruses by molecular methods and cell culture inoculation when feasible. two mus musculus domesticus trapped in the southwestern part of france were infected with a potentially new strain of lymphocytic choriomeningitis virus (lcmv), here referred to as lcmv strain hp65-2009, which was isolated and genetically characterized by whole genome sequencing. ge ... | 2012 | 22651393 |
comparing prexmrv-2 gag sequence diversity in laboratory and wild mice using deep sequencing. | it has recently been reported that the xenotropic murine leukemia virus-related virus (xmrv) derives from a laboratory recombinant. however, sequences with characteristics of the 5' half of xmrv (termed prexmrv-2) have been identified in several laboratory mouse genomes and cell lines suggesting parts of the xmrv genome exist as naturally occurring retroviruses in mice. we compare here prexmrv-2 gag sequence diversity in mice to that of reported xmrv-like sequences by testing a panel of wild mou ... | 2012 | 22771940 |
pairing alters the effect of progesterone on nesting in female c57bl/10sn mice. | progesterone treatments have been shown to increase nesting levels of isolated female mice. here we compared the effect of exogenous progesterone on the nesting behavior of c57bl/10sn female mus domesticus housed individually to nesting levels of the same mice housed in pairs. progesterone increased nesting by isolated females but had no significant effect on the nesting scores of the same mice when they were grouped into pairs. the effect of exogenous progesterone on nesting levels in c57bl/10s ... | 2012 | 3406155 |
prevalence and co-infection of toxoplasma gondii and neospora caninum in apodemus sylvaticus in an area relatively free of cats. | summarythe protozoan parasite toxoplasma gondii is prevalent worldwide and can infect a remarkably wide range of hosts despite felids being the only definitive host. as cats play a major role in transmission to secondary mammalian hosts, the interaction between cats and these hosts should be a major factor determining final prevalence in the secondary host. this study investigates the prevalence of t. gondii in a natural population of apodemus sylvaticus collected from an area with low cat densi ... | 2011 | 21756421 |
study of the efficiency of anticoagulant rodenticides to control mus musculus domesticus introgressed with mus spretus vkorc1. | antivitamin k anticoagulant (avk) rodenticides are commonly used to control rodent pests worldwide. they specifically inhibit the vkorc1 enzyme essential for the recycling of vitamin k, and thus prevent blood clotting and cause death by haemorrhage. numerous mutations or polymorphisms of the vkorc1 gene were reported in rodents, and some led to resistance to rodenticides. in house mice (mus musculus domesticus), adaptive introgression of the vkorc1 gene from the algerian mouse (mus spretus) was ... | 2017 | 27196872 |
habitat-specific shaping of proliferation and neuronal differentiation in adult hippocampal neurogenesis of wild rodents. | daily life of wild mammals is characterized by a multitude of attractive and aversive stimuli. the hippocampus processes complex polymodal information associated with such stimuli and mediates adequate behavioral responses. how newly generated hippocampal neurons in wild animals contribute to hippocampal function is still a subject of debate. here, we test the relationship between adult hippocampal neurogenesis (ahn) and habitat types. to this end, we compare wild muridae species of southern afr ... | 2013 | 23616743 |
eye morphology in some wild rodents. | the eye anatomy of six rodent species (murinae: apodemus sylvaticus, mus domesticus, and mus spretus; arvicolinae: clethrionomys glareolus, arvicola terrestris and microtus arvalis) was compared by means of light or electron microscopy to determine adaptive, and evolutive signals. our observations revealed inter-specific morphological differences, which were moderate among representatives of the same subfamily. specifically, traits that distinguished murines from arvicolines were the globe's rel ... | 2008 | 18197899 |
genetic dissection of a key reproductive barrier between nascent species of house mice. | reproductive isolation between species is often caused by deleterious interactions among loci in hybrids. finding the genes involved in these incompatibilities provides insight into the mechanisms of speciation. with recently diverged subspecies, house mice provide a powerful system for understanding the genetics of reproductive isolation early in the speciation process. although previous studies have yielded important clues about the genetics of hybrid male sterility in house mice, they have be ... | 2011 | 21750261 |
rodenticide exposure in wood mouse and house mouse populations on farms and potential secondary risk to predators. | we compared capture rates and exposure to sgars of wood mice (apodemus sylvaticus) and house mice (mus domesticus) in autumn/winter on farms that currently used, had previously used, and never used sgars. 6-10 weeks after baiting programmes began, 15 % of 55 wood mice and 33 % of 12 house mice had detectable liver sgar residues. wood mice with residues occurred on farms not using rodenticides, reflecting the high mobility of these animals, and four had multiple liver residues, possibly due to cr ... | 2012 | 22447471 |
morphometric analysis of the placenta in the new world mouse necromys lasiurus (rodentia, cricetidae): a comparison of placental development in cricetids and murids. | stereology is an established method to extrapolate three-dimensional quantities from two-dimensional images. it was applied to placentation in the mouse, but not yet for other rodents. herein, we provide the first study on quantitative placental development in a sigmodontine rodent species with relatively similar gestational time. placental structure was also compared to the mouse, in order to evaluate similarities and differences in developmental patterns at the end of gestation. | 2013 | 23433040 |
coevolution of cryptosporidium tyzzeri and the house mouse (mus musculus). | two house mouse subspecies occur in europe, eastern and northern mus musculus musculus (mmm) and western and southern mus musculus domesticus (mmd). a secondary hybrid zone occurs where their ranges meet, running from scandinavia to the black sea. in this paper, we tested a hypothesis that the apicomplexan protozoan species cryptosporidium tyzzeri has coevolved with the house mouse. more specifically, we assessed to what extent the evolution of this parasite mirrors divergence of the two subspec ... | 2013 | 23791796 |
how important are seabirds in the diet of black rats on islands with a superpredator? | this study assessed the impact of introduced black rats (rattus rattus) on cory's shearwater (calonectris diomedea borealis) in a multi-invaded insular ecosystem where rats are mesopredators. we hypothesized that black rats should have little impact on cory's shearwaters in the presence of cats as superpredators. stomach contents and stable isotope analysis (sia) in tissues of black rats were analyzed to assess the trophic ecology and the importance of cory's shearwater in their diet. we also st ... | 2014 | 24726532 |
different patterns of robertsonian fusion pairing in bovidae and the house mouse: the relationship between chromosome size and nuclear territories. | using a dataset of karyotypic changes reported for bovids and the house mouse (mus musculus domesticus) together with information from the cattle (bos taurus) and mouse genomes, we examined two principal variables that have been proposed to predict chromosomal positioning in the nucleus, chromosome size and gc content. these were expected to influence the distribution of robertsonian (rb) fusions, the predominant mode of chromosomal change in both taxa. we found the largest chromosomes to be mos ... | 2012 | 22624569 |
ancient urban ecology reconstructed from archaeozoological remains of small mammals in the near east. | modern rapidly expanding cities generate intricate patterns of species diversity owing to immense complexity in urban spatial structure and current growth trajectories. we propose to identify and uncouple the drivers that give rise to these patterns by looking at the effect of urbanism on species diversity over a previously unexplored long temporal frame that covers early developments in urbanism. to provide this historical perspective we analyzed archaeozoological remains of small mammals from ... | 2014 | 24622726 |
olfactory assessment of competitors to the nest site: an experiment on a passerine species. | since most avian species have been considered anosmic or microsmatic, olfaction and associated behavioural patterns have hardly been investigated. most importantly, empirical data on avian olfaction is not equally distributed among species. initial investigations focused on species with relatively big olfactory bulbs because they were thought to have better olfactory capabilities. hence, in this study we tested the ability of house sparrows (passer domesticus) to use chemical cues as parameters ... | 2016 | 27936093 |
age-related changes in locomotor performance reveal a similar pattern for caenorhabditis elegans, mus domesticus, canis familiaris, equus caballus, and homo sapiens. | locomotion is one of the major physiological functions for most animals. previous studies have described aging mechanisms linked to locomotor performance among different species. however, the precise dynamics of these age-related changes, and their interactions with development and senescence, are largely unknown. here, we use the same conceptual framework to describe locomotor performances in caenorhabditis elegans, mus domesticus, canis familiaris, equus caballus, and homo sapiens. we show tha ... | 2017 | 27522057 |
effects of strain and species on the septo-temporal distribution of adult neurogenesis in rodents. | the functional septo-temporal (dorso-ventral) differentiation of the hippocampus is accompanied by gradients of adult hippocampal neurogenesis (ahn) in laboratory rodents. an extensive septal ahn in laboratory mice suggests an emphasis on a relation of ahn to tasks that also depend on the septal hippocampus. domestication experiments indicate that ahn dynamics along the longitudinal axis are subject to selective pressure, questioning if the septal emphasis of ahn in laboratory mice is a rule app ... | 2017 | 29311796 |
serological survey of zoonotic viruses in invasive and native commensal rodents in senegal, west africa. | increasing studies on rodent-borne diseases still highlight the major role of rodents as reservoirs of numerous zoonoses of which the frequency is likely to increase worldwide as a result of accelerated anthropogenic changes, including biological invasions. such a situation makes pathogen detection in rodent populations important, especially in the context of developing countries characterized by high infectious disease burden. here, we used indirect fluorescent antibody tests to describe the ci ... | 2017 | 28873024 |
tempo and mode of concerted evolution in the l1 repeat family of mice. | a 300-bp dna sequence has been determined for 30 (10 from each of three species of mice) random isolates of a subset of the long interspersed repeat family l1. from these data we conclude that members of the l1 family are evolving in concert at the dna sequence level in mus domesticus, mus caroli, and mus platythrix. the mechanism responsible for this phenomenon may be either duplicative transposition, gene conversion, or a combination of the two. the amount of intraspecies divergence averages 4 ... | 1985 | 3870857 |
ecological and sanitary impacts of bacterial communities associated to biological invasions in african commensal rodent communities. | changes in host-parasite ecological interactions during biological invasion events may affect both the outcome of invasions and the dynamics of exotic and/or endemic infections. we tested these hypotheses, by investigating ongoing house mouse (mus musculus domesticus) and black rat (rattus rattus) invasions in senegal (west africa). we used a 16s gene rrna amplicon sequencing approach to study potentially zoonotic bacterial communities in invasive and native rodents sampled along two well-define ... | 2017 | 29101373 |