| neuroprotective and neurorescue effect of black tea extract in 6-hydroxydopamine-lesioned rat model of parkinson's disease. | in the present study, an attempt has been made to explore the neuroprotective and neuroreparative (neurorescue) effect of black tea extract (bte) in 6-hydroxydopamine (6-ohda)-lesioned rat model of parkinson's disease (pd). in the neuroprotective (bte + 6-ohda) and neurorescue (6-ohda + bte) experiments, the rats were given 1.5% bte orally prior to and after intrastriatal 6-ohda lesion respectively. a significant recovery in d-amphetamine induced circling behavior (stereotypy), spontaneous locom ... | 2006 | 16480889 |
| targeting angiogenesis with integrative cancer therapies. | an integrative approach for managing a patient with cancer should target the multiple biochemical and physiological pathways that support tumor development while minimizing normal tissue toxicity. angiogenesis is a key process in the promotion of cancer. many natural health products that inhibit angiogenesis also manifest other anticancer activities. the authors will focus on natural health products (nhps) that have a high degree of antiangiogenic activity but also describe some of their many ot ... | 2006 | 16484711 |
| triterpene saponins with gastroprotective effects from tea seed (the seeds of camellia sinensis). | six new triterpene saponins, theasaponins a(1) (1), a(2) (2), a(3) (3), f(1) (4), f(2) (5), and f(3) (6), were isolated from the saponin fraction of the seeds of camellia sinensis. the stereostructures of 1-6 were elucidated on the basis of chemical and physicochemical evidence. theasaponin a(2) (2) showed an inhibitory effect on ethanol-induced gastric mucosal lesions in rats at a dose of 5.0 mg/kg, p.o., and its activity was more potent than that of omeplazole. structure-activity relationships ... | 2006 | 16499314 |
| antiproliferative and apoptosis inducing effect of lactoferrin and black tea polyphenol combination on hamster buccal pouch carcinogenesis. | combination chemoprevention using tea polyphenols as one of the components has received growing consideration in recent years. the present study was designed to evaluate the antiproliferative and apoptosis inducing effects of bovine lactoferrin (blf) and black tea polyphenol (polyphenon-b: p-b) combination on 7,12-dimethylbenz[a]anthracene (dmba)-induced hamster buccal pouch (hbp) carcinogenesis. topical application of dmba for 14 weeks induced buccal pouch tumours that showed aberrant expressio ... | 2006 | 16905260 |
| correlation between the in vitro antioxidant activity and polyphenol content of aqueous extracts from bulgarian herbs. | the water phase antioxidant activity of extracts from 23 bulgarian medicinal plants was studied in relation to their polyphenol content in comparison with mate, black tea, honeybush and rooibos foreign species. antioxidant activity was measured by the abts (2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)) cation radical decolorization assay, and the total polyphenol content was assayed according to the folin-ciocalteu method. five bulgarian plant extracts exhibited higher antioxidant activ ... | 2006 | 16906640 |
| green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo. | tea [camellia sinensis (theaceae)] intake is second only to water in terms of worldwide popularity as a beverage. the green tea polyphenols have been shown to have a protective effect in prostate cancer in various pre-clinical animal models and has been reported to be effective in several other cancer types as well. an inverse association between the risk of breast cancer and the intake of green tea has also been reported in asian americans. several epidemiological studies have shown that breast ... | 2007 | 16519995 |
| beneficial effects of green tea--a review. | tea is the most consumed drink in the world after water. green tea is a 'non-fermented' tea, and contains more catechins, than black tea or oolong tea. catechins are in vitro and in vivo strong antioxidants. in addition, its content of certain minerals and vitamins increases the antioxidant potential of this type of tea. since ancient times, green tea has been considered by the traditional chinese medicine as a healthful beverage. recent human studies suggest that green tea may contribute to a r ... | 2006 | 16582024 |
| anticlastogenic effects of black tea polyphenols theaflavins and thearubigins in human lymphocytes in vitro. | black tea accounts for nearly 80% of total world tea production. it contains dimeric flavanols and polymeric polyphenols known as theaflavins (tf) and thearubigins (tr). tr is exclusively present in black tea. on the basis of our previous potent antimutagenic and anticlastogenic effects of tf and tr in vitro in bacterial system and in vivo in mouse bone marrow cells, we have decided to extend our study in human cells in vitro. this study investigated the anticlastogenic effects of black tea poly ... | 2006 | 16314069 |
| ethyl acetate extract from black tea prevents neuromuscular blockade by botulinum neurotoxin type a in vitro. | botulinum neurotoxin produced by clostridium botulinum is the strongest neurotoxin and causes botulism in mammals. the current study aimed to find an inactivator for botulinum neurotoxin in black, oolong, roasted, and green teas. the ability of the four teas to inactivate the neuromuscular blocking action of botulinum neurotoxin was determined. water extracts from black, oolong, and roasted teas protected against the toxicity of botulinum neurotoxin type a in mouse phrenic nerve-diaphragm prepar ... | 2005 | 16638658 |
| transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice. | epigallocatechin-3-gallate (egcg) is the most studied catechin in green tea (camellia sinensis). egcg and green tea are cancer preventive in many animal models, and numerous mechanisms have been proposed in cell lines. egcg is poorly bioavailable in man and rodents. we hypothesized that transdermal delivery of egcg could result in improved bioavailability. following application of egcg transdermal gel (50 mg kg(-1), t.d.) to skh-1 mice, egcg was observed in the epidermis (1365.7-121.0 ng g(-1)) ... | 2006 | 16640828 |
| plant growth promotion and induction of resistance in camellia sinensis by bacillus megaterium. | bacillus megaterium de bary trs-4 was isolated from tea rhizosphere and tested for its ability to promote growth and cause disease reduction in tea plants. in vivo studies revealed the ability of this bacterium to promote growth of tea plants very significantly. brown root rot disease, caused by fomes lamaoensis was markedly reduced by application of the bacterium to the soil. population of f. lamaoensis in soil before and after application of b. megaterium, as determined by elisa and dot-blot u ... | 2006 | 16721878 |
| protective effect of black tea against ethanol-induced oxidative modifications of liver proteins and lipids. | black tea has been recently ascertained as a source of water-soluble antioxidants that may enhance cellular antioxidant abilities. the present study was designed to investigate the efficacy of the preventive effect of black tea on oxidative modifications of liver lipids and proteins of 2-month-old rats intoxicated chronically (28 days) with ethanol. | 2006 | 16736070 |
| bioactive saponins and glycosides. xxiii. triterpene saponins with gastroprotective effect from the seeds of camellia sinensis--theasaponins e3, e4, e5, e6, and e7. | the saponin fraction from the seeds of the tea plant [camellia sinensis (l.) o. kuntze (theaceae)] was found to exhibit potent protective effects on ethanol- and indomethacin-induced gastric mucosal lesions in rats. five new triterpene saponins, theasaponins e3 (1), e4 (2), e5 (3), e6 (4), and e7 (5), were isolated together with 11 known saponins from the saponin fraction. the chemical structures of 1-5 were elucidated on the basis of chemical and physicochemical evidence. among the isolated sap ... | 2005 | 16327189 |
| safety studies on epigallocatechin gallate (egcg) preparations. part 1: genotoxicity. | public interest in green tea has grown recently due to the potential health benefits from its consumption. epigallocatechin gallate (egcg), a principal polyphenolic component of green tea, is considered key to these healthful qualities. although numerous studies have evaluated the anti-cancer effects of green tea and egcg, few have examined the safety of egcg consumption. the genotoxic potential of a concentrated egcg preparation was tested in salmonella and l5178y tk+/- mouse lymphoma cell assa ... | 2006 | 16364532 |
| in vivo and in vitro effects of tea extracts on enterotoxigenic escherichia coli-induced intestinal fluid loss in animal models. | enterotoxigenic escherichia coli (etec) infection is a major cause of dehydrating diarrhoea in infants and early-weaned piglets living under subhygienic conditions. we studied the effect of different tea types and subfractions on the intestinal fluid and electrolyte losses involved in etec diarrhoea. | 2006 | 17033520 |
| of the major phenolic acids formed during human microbial fermentation of tea, citrus, and soy flavonoid supplements, only 3,4-dihydroxyphenylacetic acid has antiproliferative activity. | dietary flavonoids are poorly absorbed from the gastrointestinal tract. colonic bacteria convert flavonoids into smaller phenolic acids (pa), which can be absorbed into the circulation and may contribute to the chemopreventive activity of the parent compounds. the purpose of our study was to determine whether flavonoids from green and black tea (gt, bt), citrus fruit with rutin (cf+r) and soy (s) supplements exposed to the same conditions in a dynamic in vitro model of the colon (tim-2) will for ... | 2006 | 16365058 |
| efficacy of 12 weeks supplementation of a botanical extract-based weight loss formula on body weight, body composition and blood chemistry in healthy, overweight subjects--a randomised double-blind placebo-controlled clinical trial. | the aim of this study was to evaluate the efficacy and safety of composite extracts in reducing weight, as the main outcome measure. secondary measures of the study were body composition change. | 2006 | 17052970 |
| membrane filtration - atomic absorption spectrometry combination for copper, cobalt, cadmium, lead and chromium in environmental samples. | cellulose nitrate membrane filter was used for the preconcentration-separation of cu, co, cd, pb and cr ions. the analyte ions were collected on the membrane filter by the aid of carmine. then membrane filter was dissolved by using nitric acid. the levels of the analytes in the final solutions were determined by flame atomic absorption spectrometry (faas). the analytical parameters including ph, amounts of carmine, sample volumes etc. have been optimized. no influences have been observed from th ... | 2007 | 17058008 |
| manufacture of a beverage from cheese whey using a "tea fungus" fermentation. | kombucha is a sour beverage reported to have potential health effects prepared from the fermentation of black tea and sugar with a "tea fungus", a symbiotic culture of acetic acid bacteria and yeasts. although black tea is the preferred substrate for kombucha fermentation, other beverages have also been tested as substrates with fair results. cheese whey is a by-product with a good amount of fermentable lactose that has been used before in the production of beverages, so the objective of this st ... | 2003 | 17061515 |
| inhibition of pathogenic bacterial adhesion by acidic polysaccharide from green tea (camellia sinensis). | an acidic polysaccharide cs-f2 from camellia sinensis was examined to characterize its anti-adhesive effects against pathogenic bacteria, most notably helicobacter pylori, propionibacterium acnes, and staphylococcus aureus. cs-f2 showed marked inhibitory activity against the pathogen-mediated hemagglutination with a minimum inhibitory concentration (mic) between 0.01 and 0.1 mg/ml, which is lower than the previously reported mic values for panax ginseng and artemisia capillaris. the inhibitory e ... | 2006 | 17090112 |
| inhibition of cwr22rnu1 tumor growth and psa secretion in athymic nude mice by green and black teas. | cancer of the prostate gland (cap), the most common invasive malignancy and a major cause of cancer related deaths in male population in the usa, is an ideal candidate disease for chemoprevention because it is typically detected in elderly population with a relatively slower rate of growth and progression. many dietary phytochemicals are showing promising chemopreventive effects, at-least in pre-clinical models of cap. our published data in cell culture and animal studies, supported by the work ... | 2006 | 16387739 |
| inhibition of angiotensin converting enzyme activity by flavanol-rich foods. | angiotensin converting enzyme (ace) activity was evaluated in the presence of flavanol-rich foods, i.e., wines, chocolates, and teas, and of purified flavonoids. all foods assayed inhibited ace activity, red wines being more effective than white wine, and green tea more effective than black tea. the inhibition of ace activity was associated with both phenolic and flavanol content in the foods. when isolated polyphenols were assayed, procyanidins (dimer and hexamer) and epigallocatechin significa ... | 2006 | 16390204 |
| the cupric ion reducing antioxidant capacity and polyphenolic content of some herbal teas. | the total antioxidant capacity of the aqueous extracts of some endemic herbs-prepared as infusions by steeping these herbs in hot water--was assayed with bis(neocuproine)copper(ii) chloride, also known as the cupric ion reducing antioxidant capacity (cuprac) reagent, which was easily accessible, rapid, stable and responsive to both hydrophilic and lipophilic antioxidants. the highest antioxidant capacities of some herbal teas available in the turkish market were observed for scarlet pimpernel (a ... | 2006 | 17135020 |
| the effects of tea extracts on proinflammatory signaling. | skin toxicity is a common side effect of radiotherapy for solid tumors. its management can cause treatment gaps and thus can impair cancer treatment. at present, in many countries no standard recommendation for treatment of skin during radiotherapy exists. in this study, we explored the effect of topically-applied tea extracts on the duration of radiation-induced skin toxicity. we investigated the underlying molecular mechanisms and compared effects of tea extracts with the effects of epigalloca ... | 2006 | 17140430 |
| protective effect of black and green tea against carbon tetrachloride-induced oxidative stress in rats. | to assess the effects of green and black tea on carbon tetrachloride (ccl4)-induced oxidative stress in rats. | 2006 | 17143353 |
| inhibitory effects of black tea theaflavin derivatives on 12-o-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears. | tea has been shown to possess several health beneficial properties primarily due to its polyphenolic content. the major polyphenolic compounds in black tea leaves are theaflavins (tfs) formed by oxidative coupling of catechins in tea leaves during its processing. in this paper, we report the characterization of 12-o-tetradecanoylphorbol-13-acetate (tpa)-induced mouse ear inflammatory model and the inhibitory effects of major black tea tfs derivatives on this inflammation. in addition, the effect ... | 2006 | 16404705 |
| neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. | teas represent a large family of plants containing high amounts of polyphenols that may confer health benefits in various diseases. recently, it has been hypothesized that tea consumption may also reduce the risk of age-related neurodegenerative pathologies. considering the deleterious role of beta-amyloid (abeta) in the aetiology of alzheimer's disease (ad), we investigated green and black tea extracts and flavan-3-ols (present as monomers and dimers in green and black forms, respectively) agai ... | 2006 | 16420415 |
| short-term bioaccumulation of vanadium when ingested with a tea decoction in streptozotocin-induced diabetic rats. | sodium orthovanadate suspended in a lichee black tea decoction effectively regulates blood glucose levels in rats with insulin-dependent, streptozotocin (stz)-induced diabetes. the primary advantage of vanadate delivery with the tea decoction over conventional systems that use water suspensions of vanadate is a significant reduction in the toxic side effects of vanadate. it is unknown if the tea alters the bioavailability of vanadate. male sprague-dawley rats were administered an intravenous inj ... | 2006 | 16423636 |
| urinary flavonoids and phenolic acids as biomarkers of intake for polyphenol-rich foods. | estimation of dietary intake of polyphenols is difficult, due to limited availability of food composition data and bias inherent to dietary assessment methods. the aim of the present study was to evaluate the associations between the intake of polyphenol-rich foods and the urinary excretion of several phenolic compounds and therefore explore whether these phenolic compounds could be used as a biomarker of intake. fifty-three participants of the su.vi.max study (a randomised primary-prevention tr ... | 2006 | 16870009 |
| tea flavanols inhibit angiotensin-converting enzyme activity and increase nitric oxide production in human endothelial cells. | a diversity of pharmacological effects on the cardiovascular system have been reported for camellia sinensis: antioxidative, antiproliferative and anti-angiogenic activity, and nitric oxide synthase activation. the purpose of this study was to investigate if the connection between tea and angiotensin-converting enzyme (ace) and nitric oxide (no) might be an explanation of the pharmacological effects of tea on the cardiovascular system. cultured endothelial cells from human umbilical veins (huvec ... | 2006 | 16872562 |
| coq9 potentiates green tea antioxidant activities in wistar rats. | green tea (camellia sinensis), and coq(9 )when given to wistar rats produced a partial reversal on reserpine induced oxidative stress and liver damage. green tea, with its abundant polyphenol (-)epigallocatechin 3-gallate (ecgc) and other catechins, is known for its antioxidative characteristics influencing lipid metabolism. ubiquinone, abundant in heart muscle, is also a potent antioxidant with known effects in numerous pathologies. however the combined effect of ecgc and ubiquninone has not be ... | 2005 | 16873954 |
| protection from experimental colitis by theaflavin-3,3'-digallate correlates with inhibition of ikk and nf-kappab activation. | inflammatory bowel disease (ibd) is associated with activation of nuclear factor kappa b (nf-kappab) involved in regulating the expression of inducible nitric oxide synthase (inos) and proinflammatory cytokine genes. as theaflavin-3,3'-digallate (tfdg), the most potent anti-oxidant polyphenol of black tea, down-regulates nf-kappab activation, we investigated if tfdg is beneficial in colonic inflammation by suppressing inos and proinflammatory cytokines. | 2006 | 16880762 |
| pre-exposure to a novel nutritional mixture containing a series of phytochemicals prevents acetaminophen-induced programmed and unprogrammed cell deaths by enhancing bcl-xl expression and minimizing oxidative stress in the liver. | from a disease-prevention perspective, recent progress in phytochemical and nutraceutical research clearly suggests (benefits outweigh the risk pattern). although powerful antioxidant properties have been the most acclaimed mechanism of action for these entities, the individual antioxidants studied in clinical trials do not appear to have consistent preventative effects. the actions of the antioxidant nutrients alone do not explain the observed health benefits of diets rich in fruits and vegetab ... | 2006 | 16902808 |
| metabonomics approach to determine metabolic differences between green tea and black tea consumption. | the purpose of this study was to compare the effects of black and green tea consumption on human metabolism. seventeen healthy male volunteers consumed black tea, green tea, or caffeine in a randomized crossover study. twenty-four-hour urine and blood plasma samples were analyzed by nmr-based metabonomics, that is, high-resolution 1h nmr metabolic profiling combined with multivariate statistics. green and black tea consumption resulted in similar increases in urinary excretion of hippuric acid a ... | 2006 | 16939360 |
| determination of trace elements in herbal tea products and their infusions consumed in thailand. | nineteen elements, mg, al, ca, v, cr, mn, fe, co, ni, cu, zn, se, sr, sb, ba, as, cd, hg, and pb, were determined in three types of popular herbal tea products, gynostemma pentaphyllum, camellia sinensis, and morus alba. these herbal tea products, both imported and locally made products, are widely consumed in thailand and worldwide. microwave-assisted acid digestion was used for all of the samples, and the element contents were determined by icp-ms. the concentrations of all elements varied amo ... | 2006 | 16939361 |
| a comparative study on the antimutagenic properties of aqueous extracts of aspalathus linearis (rooibos), different cyclopia spp. (honeybush) and camellia sinensis teas. | antimutagenic activity of aqueous extracts of the south african herbal teas, aspalathus linearis (rooibos) and cyclopia spp. (honeybush) was compared with that of camellia sinensis (black, oolong and green) teas in the salmonella mutagenicity assay using aflatoxin b(1) (afb(1)) and 2-acetylaminofluorene (2-aaf) as mutagens. the present study presents the first investigation on antimutagenic properties of c. subternata, c. genistoides and c. sessiliflora. the herbal teas demonstrated protection a ... | 2006 | 16949333 |
| differentially expression of tua1, a tubulin-encoding gene, during flowering of tea plant camellia sinensis (l.) o. kuntze using cdna amplified fragment length polymorphism technique. | the complementary dna (cdna) amplified fragment length polymorphism technique was used to isolate transcript-derived fragments corresponding to genes involved in the flowering of tea plant. comparative sequence analysis of an approximately 300 bp differential fragment amplified by primer combination e11m11 revealed 80%-84% similarity to the corresponding part of an a-tubulin gene of other species. the complete cdna sequence of this a-tubulin was cloned by the rapid amplification of cdna ends tec ... | 2006 | 16953305 |
| phenolic acids in berries, fruits, and beverages. | the contents of soluble and total phenolic acids were analyzed in samples of 29 berries and berry products, 24 fruits and fruit peels, and 12 beverages. variation of phenolic acids in berries was also studied. soluble phenolic acids were extracted with methanolic acetic acid, and a tentative quantification was performed by high-performance liquid chromatography (hplc). the total phenolic acid content was determined by hplc after alkaline and acid hydrolyses. the content of total phenolic acids a ... | 2006 | 16968082 |
| peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate. | (-)-epigallocatechin-3-gallate (egcg) is the widely studied catechin in green tea (camellia sinensis). previously, we have reported the low bioavailability of egcg in rats and mice. as a means of improving the bioavailability of egcg, we have prepared a peracetylated egcg derivative (acegcg) and herein report its growth inhibitory activity and cellular uptake in vitro, as well as bioavailability in mice. acegcg exhibited enhanced growth inhibitory activity relative to egcg in both kyse150 human ... | 2006 | 16997910 |
| pro-oxidative effects of tea and polyphenols, epigallocatechin-3-gallate and epigallocatechin, on g6pd-deficient erythrocytes in vitro. | glucose-6-phosphate dehydrogenase (g6pd)-deficient subjects are vulnerable to chemical-induced hemolysis if exposed to oxidative agents. recent studies reported that green tea and its constituents might act as pro-oxidants. our objective was to investigate effects of tea and its polyphenolic components on the oxidative status of human g6pd-deficient erythrocytes. erythrocytes of g6pd-deficient (n = 8) and normal (n = 8) subjects were incubated with water extracts of 3 types of tea samples (black ... | 2006 | 17016632 |
| glucose-lowering effect of powder formulation of african black tea extract in kk-a(y)/tajcl diabetic mouse. | we observed the suppressive effect of a powder formulation of african black tea extract prepared from the leaves of camellia sinensis on type 2 non-insulin dependent diabetic mice, kk-a(y)/tajcl. black tea extract significantly showed suppressive effect of the elevation of blood glucose on oral glucose tolerance test of 8 week-old kk-a(y)/tajcl mice (p < 0.05). long-term treatment with black tea extract showed significant suppression of post-prandial blood glucose and obesity (p < 0.05). the wei ... | 2006 | 17024853 |
| tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption. | green and black tea have shown promise in the chemoprevention of prostate cancer. the objective of this study was to determine the bioavailability and bioactivity of tea polyphenols (pp) and theaflavins in human serum and human and mouse tissues. a decaffeinated black tea diet was administered to c57bl/6 mice. pps and theaflavins were found in the small and large intestine, liver, and prostate in conjugated and free forms. the relative prostate bioavailability of theaflavin was 70% higher than t ... | 2006 | 16772446 |
| [impact of green tea on oxidative stress induced by ammonium metavanadate exposure in male rats]. | transitional metals, as vanadium, are known to exert noxious effects by generating oxidative stress. addition of antioxidants in the diet could decrease the cytotoxic effect related to the oxidative stress. the present study, carried out in wistar rats, is a contribution to the evaluation of protective effects of green tea camellia sinensis, which is known to be rich in antioxidant compounds (polyphenols...). rats were divided into four groups: (c) was control, (v) was given ammonium metavanadat ... | 2006 | 17027638 |
| green tea and skin cancer: photoimmunology, angiogenesis and dna repair. | human skin is constantly exposed to numerous noxious physical, chemical and environmental agents. some of these agents directly or indirectly adversely affect the skin. cutaneous overexposure to environmental solar ultraviolet (uv) radiation (290-400 nm) has a variety of adverse effects on human health, including the development of melanoma and nonmelanoma skin cancers. therefore, there is a need to develop measures or strategies, and nutritional components are increasingly being explored for th ... | 2007 | 17049833 |
| availability of weight-loss supplements: results of an audit of retail outlets in a southeastern city. | the sale of nonprescription weight-loss products accounts for millions of dollars spent by americans trying to lose weight, yet there is little evidence for effectiveness and there are multiple safety concerns. the purpose of this study was to determine what products, and ingredients within products, were available at retail outlets in a metropolitan area. a purposive sampling strategy identified 73 retail outlets. an audit form was used to collect information from product labels. the audit iden ... | 2006 | 17126636 |
| reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols. | the immunosuppressants ciclosporin (cyclosporin a, csa) and tacrolimus can cause severe nephrotoxicity. since csa increases free radical formation, this study investigated whether an extract from camellia sinensis, which contains several polyphenolic free radical scavengers, could prevent nephrotoxicity caused by csa and tacrolimus. rats were fed powdered diet containing polyphenolic extract (0-0.1%) starting 3 days before csa or tacrolimus. free radicals were trapped with alpha-(4-pyridyl-1-oxi ... | 2006 | 17132217 |
| epicatechins purified from green tea (camellia sinensis) differentially suppress growth of gender-dependent human cancer cell lines. | the anticancer potential of catechins derived from green tea is not well understood, in part because catechin-related growth suppression and/or apoptosis appears to vary with the type and stage of malignancy as well as with the type of catechin. this in vitro study examined the biological effects of epicatechin (ec), epigallocatechin (egc), ec 3-gallate (ecg) and egc 3-gallate (egcg) in cell lines from human gender-specific cancers. cell lines developed from organ-confined (hh870) and metastatic ... | 2006 | 16786054 |
| antibacterial properties of traditionally used indian medicinal plants. | in search of broad-spectrum antibacterial activity from traditionally used indian medicinal plants, 66 ethanolic plant extracts were screened against nine different bacteria. of these, 39 extracts demonstrated activity against six or more test bacteria. twelve extracts showing broad-spectrum activity were tested against specific multidrug-resistant (mdr) bacteria, methicillin-resistant staphylococcus aureus (mrsa) and extended spectrum beta-lactamases (esbetal)-producing enteric bacteria. in vit ... | 2007 | 17440624 |
| ecological impact of solar ultraviolet-b (uv-b: 320-290 nm) radiation on corynebacterium aquaticum and xanthomonas sp. colonization on tea phyllosphere in relation to blister blight disease incidence in the field. | to assess the effects of solar uv-b radiation on phyllosphere bacteria of tea leaves in relation to blister blight disease in the field. | 2007 | 17451518 |
| evaluation of the hypolipemic property of camellia sinensisvar. ptilophylla on postprandial hypertriglyceridemia. | a naturally decaffeinated tea, camellia sinensis var. ptilophylla (cocoa tea), has long been popular in southern china as a healthy beverage. our experiments indicate that a single oral administration of 500 mg/kg of cocoa tea extract suppresses increases in plasma triacylgycerol (tg) levels when fed with 5 ml/kg of olive or lard oil in mice and that the inhibition rates are 22.9% and 31.5%, respectively, compared with controls. under the same condition, cocoa tea extract did not affect the leve ... | 2006 | 16819905 |
| modulatory effects of black tea polyphenols on oxidant-antioxidant profile and expression of proliferation, apoptosis, and angiogenesis-associated proteins in the rat forestomach carcinogenesis model. | chemoprevention by dietary constituents has emerged as a novel approach to control stomach cancer incidence. we therefore evaluated the chemopreventive effects of black tea polyphenols (polyphenon-b) on oxidant-antioxidant status, cell proliferation, apoptosis, and angiogenesis during n-methyl-n'-nitro-n-nitrosoguanidine (mnng)-induced gastric carcinogenesis. | 2007 | 17530359 |
| pseudomonas aeruginosa immobilized multiwalled carbon nanotubes as biosorbent for heavy metal ions. | pseudomonas aeruginosa immobilized multiwalled carbon nanotubes has been used as biosorbent for the solid phase extraction of some heavy metal ions in environmental samples. cobalt(ii), cadmium(ii), lead(ii), manganese(ii), chromium(iii) and nickel(ii) ions have been selected as analytes for the presented study, due to their important negative and positive roles in human life. in order to investigate quantitative biosorption conditions of the analytes, the influences of ph of the aqueous solutio ... | 2008 | 17532628 |
| redox potential of tea infusion as an index for the degree of fermentation. | redox potential of tea infusion is suggested as an index for the extent of tea fermentation. the potential was measured between platinum and ag/agcl electrode pair with a voltmeter with high input impedance (>1000 gohms). phosphate buffer (10 mm, ph 7.0) was used to extract the infusion and served as the supporting electrolytes for the electrochemical measurement. the reliability (the nernst's behavior) for redox potential measurement was verified with a standard redox couple, ferricyanide/ferro ... | 2007 | 17560382 |
| chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways. | chemoprevention of colorectal cancer has become essential in the modern industrialized world as cancer of the large bowel has become one of the major causes of cancer mortality, second only to lung cancer. colon cancer integrates lifestyle factors and multistep genetic alterations, and without preventive intervention, a substantial part of the population is likely to develop colorectal cancer at some point during their lives. diet and nutrition clearly play a role in the etiology of colon cancer ... | 2006 | 16835502 |
| structure-activity relationships of tea compounds against human cancer cells. | the content of the biologically active amino acid theanine in 15 commercial black, green, specialty, and herbal tea leaves was determined as the 2,4-dinitrophenyltheanine derivative (dnp-theanine) by a validated hplc method. to define relative anticarcinogenic potencies of tea compounds and teas, nine green tea catechins, three black tea theaflavins, and theanine as well as aqueous and 80% ethanol/water extracts of the same tea leaves were evaluated for their ability to induce cell death in huma ... | 2007 | 17227049 |
| salivary hydrogen peroxide produced by holding or chewing green tea in the oral cavity. | tea (camellia sinensis) catechins have been studied for disease prevention. these compounds undergo oxidation and produce h(2)o(2). we have previously shown that holding tea solution or chewing tea leaves generates high salivary catechin levels. herein, we examined the generation of h(2)o(2) in the oral cavity by green tea solution or leaves. human volunteers holding green tea solution (0.1-0.6%) developed salivary h(2)o(2) with c(max) = 2.9-9.6 microm and auc(0 --> infinity) = 8.5-285.3 microm ... | 2007 | 17577746 |
| tea and cancer prevention: molecular mechanisms and human relevance. | tea made from the leaves of the plant camellia sinensis is a popular beverage. the possible cancer-preventive activity of tea and tea polyphenols has been studied extensively. this article briefly reviews studies in animal models, cell lines, and possible relevance of these studies to the prevention of human cancer. the cancer-preventive activity of tea constituents have been demonstrated in many animal models including cancer of the skin, lung, oral cavity, esophagus, stomach, liver, pancreas, ... | 2007 | 17234229 |
| black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of cox-2 and induction of caspase-3 expression. | lung cancer is one of the leading causes of cancer related death in most developed and many developing countries of the world. due to lack of validated screening methods and poor prognosis, treatment of lung cancer has not improved significantly over the last two decades. therefore the risk of the disease needs to be minimized by preventive measures. one approach for lung cancer prevention envisages reversal or restriction of precancerous lesions by chemopreventive intervention. it demands a dee ... | 2006 | 17250449 |
| in vitro evaluation of the anticancer effect of lactoferrin and tea polyphenol combination on oral carcinoma cells. | we investigated the anticancer effects of green and black tea polyphenols alone and in combination with bovine milk lactoferrin (blf) on human tongue squamous carcinoma (cal-27) and normal human gingival fibroblast (hgf) cells. both green (polyphenon-e;p-e) and black tea polyphenols (polyphenon-b;p-b) preferentially inhibit the growth of cal-27 cells in a dose-dependent manner. based on the ic(50) values, p-e was found to be more effective than p-b and the combination of p-e and blf (1:2 ratio) ... | 2007 | 17258915 |
| bioactive saponins and glycosides. xxviii. new triterpene saponins, foliatheasaponins i, ii, iii, iv, and v, from tencha (the leaves of camellia sinensis). | new triterpene saponins, foliatheasaponins i-v, were isolated from the methanolic extract of tencha [the leaves of camellia sinensis (l.) o. kuntze (theaceae)]. the chemical structures of these new saponins were elucidated on the basis of chemical and physicochemical evidence. among the new saponins, foliatheasaponins ii and iii, were found to inhibit release of beta-hexosaminidase, as a marker of antigen-induced degranulation, in rbl-2h3 cells. | 2007 | 17268104 |
| evaluation of the astringency of black tea by a taste sensor system: scope and limitation. | grading the astringency of black tea by a taste sensor system was studied. the black tea samples manufactured in india and sri lanka were classified into ten steps on the basis of two standard solutions (0.65 mm and 0.26 mm egcg aqueous solutions). an organoleptic test demonstrated that the sensor output was correlative to the human gustatory sense. | 2007 | 17284831 |
| black tea prevents cigarette smoke-induced apoptosis and lung damage. | cigarette smoking is a major cause of lung damage. one prominent deleterious effect of cigarette smoke is oxidative stress. oxidative stress may lead to apoptosis and lung injury. since black tea has antioxidant property, we examined the preventive effect of black tea on cigarette smoke-induced oxidative damage, apoptosis and lung injury in a guinea pig model. | 2007 | 17300721 |
| thea sinensis melanin prevents cisplatin-induced nephrotoxicity in mice. | the preventive effect of thea sinensis melanin (tsm) against cisplatin-induced nephrotoxicity was studied on icr mice. animals were given 20mg/kg i.p. of cisplatin, and tsm was injected i.p. in doses 10-40 mg/kg 2h before intoxication. the protective effects were evidenced by a complete inhibition of the cisplatin-induced elevation of serum blood urea nitrogen (bun), prevention of oxidative stress, and complete blockade of cisplatin-induced elevation of serum creatinine. tsm by itself, however, ... | 2007 | 17303299 |
| compositional analysis and preliminary toxicological evaluation of a tea polysaccharide conjugate. | tea polysaccharide conjugate is one of the main bioactive constituents of tea (camellia sinensis l.). the chemical composition and preliminary toxicological evaluation of a tea polysaccharide conjugate was investigated to determine the possibility of using it for human consumption. chemical analysis of tea polysaccharide conjugate showed that the tea polysaccharide conjugate was a nonstarch protein bounded acidic polysaccharide. the protein, neutral sugar, and uronic acid content of the tea poly ... | 2007 | 17305361 |
| biosorption of copper(ii), lead(ii), iron(iii) and cobalt(ii) on bacillus sphaericus-loaded diaion sp-850 resin. | the biosorption of copper(ii), lead(ii), iron(iii) and cobalt(ii) on bacillus sphaericus-loaded diaion sp-850 resin for preconcentration-separation of them have been investigated. the sorbed analytes on biosorbent were eluted by using 1 mol l(-1) hcl and analytes were determined by flame atomic absorption spectrometry. the influences of analytical parameters including amounts of ph, b. sphaericus, sample volume etc. on the quantitative recoveries of analytes were investigated. the effects of alk ... | 2007 | 17386450 |
| influence of regular black tea consumption on tobacco associated dna damage and hpv prevalence in human oral mucosa. | black tea is more widely consumed than green tea worldwide, particularly in india. therefore, it is necessary to focus attention on black tea with respect to its health promoting and anti-cancer actions. in order to establish the concept that black tea is a potential candidate for cancer prevention, it is important to provide epidemiological evidence derived from investigations of human populations. in view of this, the objective of the present study was to determine the correlation between natu ... | 2007 | 17696743 |
| theanine prevents memory impairment induced by repeated cerebral ischemia in rats. | the present study investigated the neuroprotective effect of gamma-glutamylethylamide (theanine), a component japanese green tea (camellia sinensis), on memory impairment induced by twice-repeated cerebral ischemia in rats. theanine was injected i.p. immediately after the first occlusion. theanine (0.3 and 1 mg/kg) significantly prevented the impairment of spatial memory in rats subjected to repeated cerebral ischemia, 7 days after the second reperfusion. moreover, theanine (1 mg/kg) significant ... | 2008 | 17705146 |
| theaflavins attenuate hepatic lipid accumulation through activating ampk in human hepg2 cells. | black tea is one of the world's most popular beverages, and its health-promoting effects have been intensively investigated. the antiobesity and hypolipidemic effects of black tea have attracted increasing interest, but the mechanisms underlying these phenomena remain unclear. in the present study, the black tea major component theaflavins were assessed for their hepatic lipid-lowering potential when administered in fatty acid overload conditions both in cell culture and in an animal experimenta ... | 2007 | 17720960 |
| inhibition of 17alpha-hydroxylase/c17,20-lyase (cyp17) from rat testis by green tea catechins and black tea theaflavins. | in the course of screening for 17alpha-hydroxylase/c17,20-lyase inhibitors from food ingredients, the methanol soluble fraction of green tea and black tea, which were expected to be rich in catechin and theaflavin content, showed potent inhibitory activity. (-)-epigallocathechin gallate and theaflavin 3-o-gallate with a pirogallol moiety significantly inhibited c17,20-lyase activity on ic50 values of 24.5 microm and 11.5 microm respectively. they had potent cytotoxicity against human prostate ca ... | 2007 | 17827674 |
| evaluation of chemopreventive agents for genotoxic activity. | we conducted genetic toxicity evaluations of 11 candidate chemopreventive agents with the potential for inhibiting carcinogenesis in humans at increased risk of cancer. the compounds were evaluated for bacterial mutagenesis in the salmonella-e. coli assay, for mammalian mutagenesis in mouse lymphoma cells, for chromosome aberrations in chinese hamster ovary (cho) cells, and for micronucleus induction in mouse bone marrow. tested agents were indole 3-carbinol (i3c), bowman-birk inhibitor concentr ... | 2007 | 17387038 |
| use of tea extracts (camelia sinensis) in jelly candies as polyphenols sources in human diet. | diet rich in polyphenols may be important factor in preventing cardiovascular, neoplastic diseases and slowing down the aging processes. because tea (camelia sinensis) is most popular beverage containing relatively large amounts of polyphenols, it could be tremendously important source of polyphenolic constituents in human diet. however, there has been no data on the tea extracts use in particular everyday snacks. objective of the study was to investigate potential use of tea polyphenol extracts ... | 2007 | 17392075 |
| theaflavin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-inflammatory effect and modulation of stat-1. | theaflavin, a major constituent of black tea, possesses biological functions such as the antioxidative, antiviral, and anti-inflammatory ones. the purpose of this study was to verify whether theaflavin reduces focal cerebral ischemia injury in a rat model of middle cerebral artery occlusion (mcao). male sprague-dawley rats were anesthetized and subjected to 2 hours of mcao followed 24 hours reperfusion. theaflavin administration (5, 10, and 20 mg/kg, i.v.) ameliorated infarct and edema volume. t ... | 2006 | 17392572 |
| cellular responses and proteomic analysis of escherichia coli exposed to green tea polyphenols. | the purpose of this study was to characterize the cellular response and proteomic analysis of escherichia coli exposed to tea polyphenols (tpp) extracted from korean green tea (camellia sinensis l). tpp showed a dose-dependent bactericidal effect on e. coli. analysis of cell-membrane fatty acids of e. coli cultures treated with tpp identified unique changes in saturated and unsaturated fatty acids, whereas scanning electron microscopic analysis demonstrated the presence of perforations and irreg ... | 2007 | 17874165 |
| breast cancer prevention by green tea catechins and black tea theaflavins in the c3(1) sv40 t,t antigen transgenic mouse model is accompanied by increased apoptosis and a decrease in oxidative dna adducts. | tea consumption is associated with a reduced risk of mammary cancer as reflected by epidemiological studies and experiments in carcinogen-induced rodent models of mammary carcinogenesis. we tested the hypothesis that green tea catechins (gtc) or theaflavins from black tea (btt) interfere with mammary carcinogenesis in c3(1) sv40 t,t antigen transgenic multiple mammary adenocarcinoma (tag) mice and that gtc/btt affect tumor survival or oxidation status. tag mice received gtc/btt (0.05%) in drinki ... | 2007 | 17407311 |
| specific formulation of camellia sinensis prevents cold and flu symptoms and enhances gamma,delta t cell function: a randomized, double-blind, placebo-controlled study. | determine if a specific formulation of camellia sinensis (csf) can prevent illness and symptoms due to cold and flu, and enhance gammadelta t cell function | 2007 | 17914132 |
| acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects. | plasma total homocysteine concentrations (thcy) are a putative risk factor for cvd. tea is a rich dietary source of polyphenols and caffeine, both of which may raise thcy. however, it is possible that much of any effect is transitory and may be influenced by the consumption of food. our objective was to investigate the acute effect of tea, at a dose representative of ordinary population intakes, on thcy and to determine whether consumption of a meal influences the magnitude of any effect. measur ... | 2007 | 17408524 |
| theaflavins induce g2/m arrest by modulating expression of p21waf1/cip1, cdc25c and cyclin b in human prostate carcinoma pc-3 cells. | cancer of the prostate gland (pca) is the most common invasive malignancy and is the second leading cause of cancer-related death in males. the polyphenolic constituents of black tea have gained considerable attention as chemopreventive agents. many studies have shown that black tea reduces the risk of several cancer types. in the present study, we studied the effect of a black tea polyphenol, theaflavin (tf), on cellular proliferation and cell death in the human prostate cancer cell line, pc-3. ... | 2007 | 17936851 |
| serological detection and immunogold localization of cross-reactive antigens shared by camellia sinensis and exobasidium vexans. | pathogenicity of exobasidium vexans, causal agent of blister blight of tea, was studied in 30 commercially cultivated tea varieties by analysing the antigenic patterns of host and pathogen using immunological techniques. | 2007 | 17953578 |
| medicinal flowers. xiv. new acylated oleanane-type triterpene oligoglycosides with antiallergic activity from flower buds of chinese tea plant (camellia sinensis). | the methanolic extract from the flower buds of chinese tea plant (camellia sinensis (l.) o. kuntze) was found to inhibit release of beta-hexosaminidase from rbl-2h3 cells. from the methanolic extract, six new acylated oleanane-type triterpene oligoglycosides, floratheasaponins d-i, were isolated together with 21 known compounds including floratheasaponins a-c. the chemical structures of floratheasaponins d-i were elucidated on the basis of chemical and physicochemical evidence. the principal con ... | 2007 | 17409555 |
| chemoprevention of rat mammary carcinogenesis by black tea polyphenols: modulation of xenobiotic-metabolizing enzymes, oxidative stress, cell proliferation, apoptosis, and angiogenesis. | chemoprevention of dietary constituents has emerged as a cost-effective approach to control the incidence of breast cancer. the present study was therefore designed to evaluate the chemopreventive efficacy of black tea polyphenols (polyphenon-b) during the preinitiation phase of 7,12-dimethylbenz[a]anthracene (dmba) induced mammary carcinogenesis using xenobiotic-metabolizing enzymes, cellular redox status, cell proliferation, apoptosis, and angiogenesis as biomarkers of chemoprevention. intraga ... | 2007 | 17415784 |
| [effect of plant biocomposites based on georgian tea "per se" and in combination with cisplatin on walker carcinosarcoma w-256 and guerin's carcinoma growth rate in rats]. | green tea biocomposite had effectivey hampered the growth of rat walker w-256 carcinoma and in less extent rat guerin's carcinoma. black tea biocomposite had not practically influenced on guerin's carcinoma growth. the biocomposite from green tea and extract from red vine rind and lemon suppressed at the level of tendency the growth of rat walker w-256 carcinoma. the biocomposite from green tea and extract from red vine rind had hampered only guerin's carcinoma growth and at the tendency had inc ... | 2006 | 17427433 |
| overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas. | tea leaves produce organic compounds that may be involved in the defense of the plants against invading pathogens including insects, bacteria, fungi, and viruses. these metabolites include polyphenolic compounds, the six so-called catechins, and the methyl-xanthine alkaloids caffeine, theobromine, and theophylline. postharvest inactivation of phenol oxidases in green tea leaves prevents oxidation of the catechins, whereas postharvest enzyme-catalyzed oxidation (fermentation) of catechins in tea ... | 2007 | 17195249 |
| a major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting hmgb1. | the pathogenesis of sepsis is mediated in part by bacterial endotoxin, which stimulates macrophages/monocytes to sequentially release early (e.g., tnf, il-1, and ifn-gamma) and late (e.g., hmgb1) pro-inflammatory cytokines. our recent discovery of hmgb1 as a late mediator of lethal sepsis has prompted investigation for development of new experimental therapeutics. we previously reported that green tea brewed from the leaves of the plant camellia sinensis is effective in inhibiting endotoxin-indu ... | 2007 | 17987129 |
| black tea ameliorates aflatoxin-induced lipid peroxidation in the kidney of mice. | oral administration of 25 and 50 mg of aflatoxin in 0.2 ml olive oil/animal/day for 30 days caused dose-dependent and significantly higher lipid peroxidation in the kidney of aflatoxin-treated mice than in the controls. the levels of non-enzymatic antioxidant such as glutathione as well as the enzymatic antioxidants such as superoxide dismutase, glutathione peroxidase and catalase were significantly lower in the kidney of aflatoxin-treated mice than in the controls. black tea extract (2%) treatm ... | 2006 | 17203869 |
| monitoring the binding processes of black tea thearubigin to the bovine serum albumin surface using quartz crystal microbalance with dissipation monitoring. | the binding processes of thearubigin, which is one of the two major polyphenols (the other one is theaflavin) that gives black tea its characteristic color and taste, to the bovine serum albumin (bsa) surface have been investigated by quartz crystal microbalance with dissipation monitoring (qcm-d). the mass and thickness of the thearubigin adlayer on bsa surfaces at various thearubigin concentrations, salt concentrations, and ph values have been determined by qcm-d using the voigt model. our res ... | 2007 | 18031008 |
| green tea [camellia sinensis (l.) o. kuntze] extract reverses the despair behaviour in reserpinised and diabetic mice. | green tea (c. sinensis) extract (gte) dose dependently produced reversal of despair in normal, reserpinised and diabetic mice, thereby demonstrating an antidepressant effect. although the exact mechanism is yet to be explored, the possible inhibition of catechol-o-methyl transferase and monoamine oxidase enzymes may be responsible for antidepressant activity of gte. | 2006 | 17205714 |
| both aluminum and polyphenols in green tea decoction (camellia sinensis) affect iron status and hematological parameters in rats. | green tea leaves naturally contain high levels of polyphenols and aluminum (al). polyphenols in green tea decoction are considered to be one of the major factors responsible of low iron status. however, the effects of al from green tea decoction on iron status and hematological parameters remained unclear. | 2007 | 18060378 |
| cloning and characterization of a cytosolic glutamine synthetase from camellia sinensis (l.) o. kuntze that is upregulated by aba, sa, and h2o2. | a cdna encoding glutamine synthetase, one of the enzymes of the gs/gogat pathway, was cloned from camellia sinensis (csgs). the isolated cdna consists of 1,071 nucleotides encoding a polypeptide of 356 amino acids with an estimated isoelectric point of 6.13. the recombinant protein purified from escherichia coli using ni-nta affinity chromatography showed molecular mass of 39.2 kda. the purified protein was confirmed by blotting with anti-his antibodies. catalytic parameters of the protein were ... | 2008 | 18074244 |
| addition of milk prevents vascular protective effects of tea. | experimental and clinical studies indicate that tea exerts protection against cardiovascular diseases. however, a question of much debate is whether addition of milk modifies the biological activities of tea. we studied the vascular effects of tea, with or without milk, in humans and elucidated the impact of individual milk proteins in cell culture experiments, with isolated rat aortic rings and by hplc analysis. | 2007 | 17213230 |
| chemical profiling and gene expression profiling during the manufacturing process of taiwan oolong tea "oriental beauty". | oriental beauty, which is made from tea leaves infested by the tea green leafhopper (jacobiasca formosana) in taiwan, has a unique aroma like ripe fruits and honey. to determine what occurs in the tea leaves during the oolong tea manufacturing process, the gene expression profiles and the chemical profiles were investigated. tea samples were prepared from camellia sinensis var. sinensis cv. chin-shin dah-pang while the tea leaves were attacked by the insect. the main volatile compounds, such as ... | 2007 | 17587678 |
| artemisia herba-alba asso (asteraceae) has equivalent effects to green and black tea decoctions on antioxidant processes and some metabolic parameters in rats. | the objective was to compare the long-term effects of artemisia herba-alba asso decoction with a green or black tea decoction, prepared without sugar, on the antioxidant processes in rats. | 2007 | 17587792 |
| effect of nr-anx-c (a polyherbal formulation) on haloperidol induced catalepsy in albino mice. | use of typical antipsychotics like haloperidol in treatment of schizophrenia is associated with a high incidence of extrapyramidal side effects. in rodents, administration of haloperidol leads to the development of a behavioural state called catalepsy, in which the animal is not able to correct an externally imposed posture. in the present study we evaluated the anticataleptic efficacy of nr-anx-c, a polyherbal formulation containing bioactives of withania somnifera, ocimum sanctum, camellia sin ... | 2007 | 18160755 |
| selective microbiologic effects of tea extract on certain antibiotics against escherichia coli in vitro. | this study evaluated the microbiologic effects of black tea, compared to green tea, alone and in conjunction with selected antibiotics against escherichia coli, the common cause of intestinal and urinary tract infections. | 2007 | 18166124 |
| elevation protective role of camellia sinensis and urtica dioica infusion against trichloroacetic acid-exposed in rats. | this study was designed to investigate the protective effects of two traditionally used turkish medicinal plants, camellia sinensis (cs) and urtica dioica l. (ud), beverages used against chemical carcinogen trichloroacetic acid (tca)-exposure in rats. the preventive potential of the plant infusions was evaluated by measuring the level of serum marker enzymes, aspartate aminotransferase (ast), alanine aminotransferase (alt), creatine phosphokinase (cpk), acid phosphatase (acp), alkaline phosphata ... | 2007 | 17622976 |
| determination of in vitro antidiabetic effects, antioxidant activities and phenol contents of some herbal teas. | in this research, some herbal teas and infusions traditionally used in the treatment of diabetes in turkey, have been studied for their antidiabetic effects on in vitro glucose diffusion and phenolic contents and antioxidant activities. ten aqueous herbal tea extracts were examined using an in vitro method to determine their effects on glucose movement across the gastrointestinal tract. total phenol content of herbal teas was analyzed by folin-ciocalteu's procedure. antioxidant activities of her ... | 2008 | 18183488 |
| expression and purification of his-tagged flavonol synthase of camellia sinensis from escherichia coli. | flavonols, a class of bioactive polyphenols present in plants, are the products of flavonol desaturation catalyzed by flavonol synthase (fls). we cloned the cdna coding for the enzyme fls from camellia sinensis (csfls) by end-to-end pcr followed by 5'- and 3'-race. the putative csfls had 333 amino acid residues, displayed identities to the flss of arabidopsis and ginkgo of 53% and 52.5%, respectively, and contained several conserved elements found in the 2-oxoglutarate-fe(ii)-dioxygenase superfa ... | 2007 | 17629496 |
| black tea-induced decrease in il-10 and tgf-beta of tumor cells promotes th1/tc1 response in tumor bearer. | several lines of evidence support that impairment of host immune function by tumor may be related to several strategies of tumor escape from immunosurveillance. we found that in ehrlich's ascites carcinoma (eac)-bearing mice, the tumor cells secrete immunosuppressive cytokines, transforming growth factor beta (tgf-beta) and interleukin-10 (il-10) that induce a general t helper cells type 2 (th2) dominance dampening the t cytotoxic cells type 1 (tc1) population. interestingly, black tea at the an ... | 2007 | 17640168 |
| the association between personal habits and bladder cancer in turkey. | in this study, we analyzed the effect of turkish coffee and black tea consumption, alcohol intake and smoking on bladder cancer. | 2008 | 18247151 |
| studies of the antioxidative effects of green and black tea (camellia sinensis) extracts in rats. | this paper reports a comparative study of the antioxidative effects of black and green tea extracts in sodium oxalate-challenged rats. a dose of 10 mg/kg of body weight of sodium oxalate was used to induce lipid peroxidation in vivo. rats treated with sodium oxalate had 42.06 +/- 3.10 nm/hour, 45.39 +/- 9.75 mg/100 ml, 10.95 +/- 1.52%, 15.95 +/- 3.19 mg/dl, 112.25 +/- 5.15 mg/dl, 59.21 +/- 2.95 iu, 39.55 +/- 2.51 iu, and 150.62 +/- 9.62 ka/unit for serum levels of malondialdehyde, reduced ascorb ... | 2007 | 17651072 |
| the effect of green, black and white tea on the level of alpha and gamma tocopherols in free radical-induced oxidative damage of human red blood cells. | the present study was undertaken to investigate the effect of aqueous tea extracts on lipid peroxidation and alpha and gamma tocopherols concentration in the oxidative damage of human red blood cells (rbc). rbc was taken as the model for study of the oxidative damage was induced by cumene hydroperoxide (cumooh). the antioxidative property of leaf green tea, leaf and granulate of black tea and white tea at levels 1, 2, 4 g/150 ml of water were evaluated. the correlation was observed between reduc ... | 2007 | 17665865 |