| polymicrobial nature of vaginitis in young women: a microbiological and therapeutic study. | thirty-six young females attending the student health service with vaginitis were investigated by serial semiquantitative aerobic, anaerobic, fungal, mycoplasma and viral cultures over a 10 day period and results were correlated with signs and symptoms. antifungal therapy (econazole pessaries and cream) resulted in clearance of candida from 13 out of 16 patients where there was no increase in the anaerobic flora. in the four subjects where candida was isolated along with gardnerella vaginalis pl ... | 1982 | 6283441 |
| association of ureaplasma urealyticum in the placenta with perinatal morbidity and mortality. | we investigated the presence of ureaplasmas, mycoplasmas, chlamydiae, fungi, aerobic and anaerobic bacteria, and cytomegalovirus in fetal membranes and evaluated their association with perinatal morbidity and mortality. we cultured 801 placentas from three groups of subjects (144 who died in the perinatal period, 452 neonates admitted to the intensive-care unit, and 205 controls). ureaplasma urealyticum, mycoplasma hominis, or both were isolated from 21 per cent of placentas of premature and ter ... | 1984 | 6321990 |
| a prospective study of chlamydial, mycoplasmal, and viral infections in a neonatal intensive care unit. | in a prospective study of non-bacterial infection in a neonatal intensive care unit in north west london, chlamydia trachomatis infection was identified in 4 of 280 babies (1.4%) and was the most common cause of neonatal ophthalmia. one of the four developed pneumonitis. ureaplasma urealyticum was found to colonise the nasopharynx in 53 of 235 babies (22.6%), with mycoplasma hominis present in 6 of 235 babies (2.6%). there was a statistically significant association between u urealyticum colonis ... | 1984 | 6322705 |
| vaginal colonization with gardnerella vaginalis and anaerobic curved rods. | ninety-four women colonized with anaerobic curved rods (cr) and/or gardnerella vaginalis, were studied. of these women, 34 were culture-positive for the long variant of cr. eight of these latter women also harboured the short variant of these bacteria. in women colonized with cr, none had a predominance of lactobacilli in their vaginal flora, which was the case in 26 of the 60 women not harbouring cr. g. vaginalis was isolated from all 94 women. mycoplasma hominis occurred significantly more oft ... | 1984 | 6336131 |
| application of monoclonal antibodies to detect intraocular mycoplasma antigens in mycoplasma arthritidis-infected sprague-dawley rats. | sprague-dawley rats infected with mycoplasma arthritidis by tail vein inoculation develop extensive disseminated joint inflammation, frequently accompanied by conjunctivitis and anterior uveitis. the intraocular inflammation is apparently directed at mycoplasmas localized within the stroma of the ciliary body, which have been detected with monoclonal antibodies by indirect immunofluorescence. the monoclonal antibodies are directed against an antigenic determinant on the enzyme arginine deiminase ... | 1983 | 6339406 |
| septicaemia in a renal transplant patient due to mycoplasma hominis. | opportunistic infections are an important cause of mortality in transplant patients. here we report a case of mycoplasma hominis septicaemia in a renal transplant patient that was successfully treated with doxycycline. | 1983 | 6350477 |
| mycoplasma hominis - a neglected human pathogen. | | 1983 | 6354713 |
| mycoplasma hominis: historical outline and taxonomy. | although known as a separate group of organisms since 1898, the isolation in 1937 of a human genital mycoplasma represented the first observation of the association of this group of organisms with humans, a discovery that provided the impetus for extensive investigations of the interactions of mycoplasmas with the human host. these studies showed that mycoplasmas were frequent inhabitants of the mucous membranes of the urogenital and upper respiratory tracts. in early studies of human mycoplasma ... | 1983 | 6364403 |
| morphology of the cells and colonies of mycoplasma hominis. | studies of the morphology mycoplasma hominis have shown that the cells resemble those of small coccoid or ovoid bacteria; the microstructure of the organism is compatible with reproduction by a fission process. although dividing forms with equal-sized lobes are common, fragmenting filaments and replicating buds sometimes occur, perhaps in response to suboptimal growth conditions. data based on morphometric analysis show that cells of m. hominis atcc 14027 have average dimensions of 0.27 x 0.74 m ... | 1983 | 6364404 |
| enzyme immunoassay for serum antibody to mycoplasma hominis in women with acute pelvic inflammatory disease. | a sensitive, four-layer modification of an enzyme immunoassay was developed for the determination of serum antibodies to mycoplasma hominis. the suitability of the test for diagnostic use was studied with women who had acute pelvic inflammatory disease (pid). twenty (23%) of 86 women with pid from whom paired sera were obtained demonstrated a significant change in levels of igg antibody, a finding suggestive of recent infection with m. hominis. the occurrence of such change was not related to th ... | 1983 | 6364405 |
| occurrence and pathogenicity of mycoplasma hominis in the upper urinary tract: a review. | in two studies mycoplasma hominis was isolated from the upper urinary tracts of seven of 80 patients with symptoms of acute pyelonephritis and three of 18 patients with signs of acute exacerbation of chronic pyelonephritis. m. hominis was not recovered from the upper urinary tract of 22 patients with chronic pyelonephritis without acute exacerbation or from 60 patients with noninfectious urinary tract disease. in an additional study, specimens were cultured from patients with antibodies to m. ho ... | 1983 | 6364406 |
| antimicrobial susceptibility and susceptibility testing of mycoplasma hominis: a review. | the determination of the minimal growth-inhibiting concentration (mic), the minimal metabolism-inhibiting concentration (mmc), and the minimal mycoplasmacidal concentration (mcc) of various antimicrobial compounds for mycoplasma hominis is influenced by the ph of the test media, the inoculum size, and the incubation time, although each of these factors generally do not affect the minimal concentration more than fourfold. m. hominis is resistant to beta-lactam antibiotics, vancomycin, sulfonamide ... | 1983 | 6364407 |
| immunoglobulin a protease activity of ureaplasma urealyticum. | all of 14 serotype standards and 34 of 35 wild-type strains of ureaplasma urealyticum isolated from humans demonstrated an immunoglobulin a (iga) protease activity. this activity degraded radiolabeled human iga including iga1 but not igg or azocasein. the iga fragments were detected by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, followed by radioautography, and they had molecular weights of about 110,000 and 50,000. the iga protease activity persisted in 25 mm edta but was sensiti ... | 1984 | 6365962 |
| detection of mycoplasma hominis antigen in clinical specimens by using a four-layer modification of enzyme immunoassay (eia). | a 4-layer modification of enzyme immunoassay (eia) was developed for the detection of mycoplasma hominis antigen in clinical specimens. microtiter plates were sensitized with rabbit anti-mycoplasma immunoglobulin, guinea pig anti-mycoplasma immunoglobulin was used as the secondary antibody, and horseradish peroxidase-conjugated anti-guinea pig immunoglobulin was used as the indicator antibody. the specificity of the assay was confirmed by using guinea pig immunoglobulins from preimmunization ser ... | 1984 | 6371147 |
| mycoplasmic localization patterns on spermatozoa from infertile men. | two mycoplasmas have been observed with increasing frequency in patients with genitourinary disorders: mycoplasma hominis and ureaplasma urealyticum. mycoplasma cells of both these species have been demonstrated to be capable of attaching to human spermatozoa of infertile patients. the mechanisms for the association of infertility and mycoplasma infection have not been established. the main objective of this article was to explain the significance of some morphologic features of spermatozoa of p ... | 1984 | 6381102 |
| mycoplasmal pid: a review of natural and experimental infections. | the present report is a review of data assuming an etiological relationship between pelvic inflammatory disease (pid) and mycoplasma hominis. thus the organism can be isolated from the vagina/cervix more frequently in pid patients than in any other clinical group, i.e., in half to three-fourths of all such cases. one-fourth of pid patients develop a significant antibody response to m. hominis during the course of the disease. the antibody response can be detected by indirect hemagglutination tes ... | 1983 | 6382823 |
| [gonorrheal urethritis--frequently a mixed chlamydia and mycoplasma infection. results in 143 male patients with acute gonorrhea]. | chlamydia trachomatis, ureaplasma urealyticum and mycoplasma hominis are frequently demonstrated in cases of acute gonorrhoeic urethritis. among 143 males (average age 22.5 years) chlamydia was demonstrated in 29%, u. urealyticum in 34% and m. hominis in 13%. penicillin treatment of gonorrhoea does not affect chlamydia and mycoplasma so that these organisms will persist in the lower urogenital tract. generally postgonorrhoeic urethritis is associated with chlamydia or mycoplasma infection. nearl ... | 1983 | 6406199 |
| mycoplasma hominis septicaemia. | mycoplasma hominis septicaemia occurred in a patient with a malignant lymphoma of lymphoblastic type in leukaemic phase. m hominis was isolated several times from blood cultures with antibody titres against the micro-organism rising to a high level despite severe immunosuppression. m hominis was detected in the blood after subculture of the blood culture bottles despite their macroscopically normal appearance. the patient's pyrexia resolved without treatment with antibiotics effective against m ... | 1983 | 6409207 |
| the genetic relation between mycoplasma hominis and other mycoplasma species. | purified preparations of dna from five mycoplasma species of human origin, including mycoplasma hominis, were analyzed for homology. in general, very low-level homology (less than 0.5%) was found, but two pairs of species showed greater homology: m. hominis and mycoplasma salivarium were related by a 2.6% homology, mycoplasma pneumoniae and mycoplasma genitalium (a proposed new species) were related by a 1.8% homology. these results indicate that the species involved are distinct but distantly r ... | 1983 | 6420911 |
| interaction between trichomonas vaginalis and other pathogenic micro-organisms of the human genital tract. | trichomonas vaginalis organisms were mixed with suspensions of neisseria gonorrhoeae, mycoplasma hominis or chlamydia trachomatis to allow ingestion of these micro-organisms by the trichomonads. culture studies indicated that gonococci and mycoplasmas were ingested and that the number of intracellular viable organisms decreased rapidly, most gonococci being killed within six hours and all mycoplasmas within three hours. electron microscopy revealed phagocytic uptake and destruction of these two ... | 1984 | 6421451 |
| effects of manganese on the growth and morphology of ureaplasma urealyticum. | all of the 14 serotype standard strains of ureaplasma urealyticum were inhibited to varying degrees by manganese. a 1 mm concentration of this cation either stopped growth or reduced the rate of growth in liquid medium. the presence of manganese also altered colonial morphology and cellular ultrastructure. inhibition was dose dependent and strain specific. this differential response allowed the serotype strains to be divided into two broad biotypes. for the first biotype (serotypes 1, 3, 6, and ... | 1984 | 6432835 |
| the role of mycoplasmas in non-gonococcal urethritis: a review. | the criteria that need to be fulfilled before regarding a mycoplasma as a cause of non-gonococcal urethritis (ngu) are outlined. of the seven mycoplasmas that have been isolated from the human genitourinary tract, most cannot be considered as contenders for causing ngu. although there is no evidence to support an etiological role for mycoplasma hominis, it may be unwise to ignore this mycoplasma in view of its known pathogenicity in other situations. the cumulative weight of evidence indicates t ... | 1983 | 6433572 |
| the co-existence of genital mycoplasma and neisseria gonorrhoeae isolated from the male urethra. | ureaplasma urealyticum and mycoplasma hominis, separately or together, were co-isolated along with 34 of 102 strains of neisseria gonorrhoeae cultured from urethral swabs from men with urethritis. for approximately half of the n. gonorrhoeae strains, the mycoplasma(s) persisted for at least five passages on agar medium. u. urealyticum was isolated in 31 of the 34 instances. no association between particular serotype(s) of u. urealyticum or auxotypes of n. gonorrhoeae was identified. the auxotype ... | 1984 | 6438816 |
| microbiology of specimens obtained by laparoscopy from controls and from patients with pelvic inflammatory disease or infertility with tubal obstruction: chlamydia trachomatis and ureaplasma urealyticum. | we cultured for chlamydia trachomatis, ureaplasma urealyticum, and mycoplasma hominis and performed chlamydial serologic studies in 99 women undergoing laparoscopy. these women included patients with acute salpingitis, infertile women with and without mild pelvic inflammatory disease, and controls. c. trachomatis infection was significantly more common in patients than in controls. we also identified low-grade "silent" pid among women with infertility resulting from tubal obstruction and suggest ... | 1980 | 6451177 |
| influence of ureaplasma urealyticum and mycoplasma hominis on the human spermatozoal motility. | | 1984 | 6480368 |
| isolation of ureaplasma urealyticum and mycoplasma hominis from patients with genitourinary tract infection. | | 1984 | 6480371 |
| mycoplasma hominis--a human pathogen. | | 1984 | 6505919 |
| a prospective study of mycoplasma infection in the preterm infant. | the nasopharyngeal aspirates of 235 infants admitted to the neonatal intensive care unit over a 14-month period were tested for the presence of ureaplasma urealyticum and mycoplasma hominis. serological studies were carried out on 41 infants. u. urealyticum was isolated from 53 (22%) babies and was not associated with illness. there was a significant association between u. urealyticum colonization and preterm birth, low birth weight and prolonged rupture of membranes (prom). m. hominis was isola ... | 1984 | 6511316 |
| do mycoplasmas inhibit the human sperm fertilizing ability in vitro? | although clinical observations have suggested that ureaplasma urealyticum may be associated with reproductive failure, the role of ureaplasmas in human infertility remains controversial. however, the mechanism whereby ureaplasmas can interfere with the fertilization process is not known. to study possible mechanisms, we used the human sperm-hamster egg fertilization test. eggs were exposed to the spermatozoa preincubated with mycoplasma hominis or u. urealyticum (serotype 1-8). u. urealyticum se ... | 1984 | 6511317 |
| spontaneous abortion--an infectious aetiology? | the role of chlamydia trachomatis, genital mycoplasmas, campylobacter spp. and other aerobic and anaerobic bacteria in the aetiology of spontaneous abortion was investigated prospectively in 241 pregnant women at a community hospital. sixteen women who had threatened abortions were a little younger, of lower social class and had had more previous spontaneous abortions than the 76 women who aborted or the 149 women whose pregnancies were not complicated in the early stages by haemorrhage. the dem ... | 1984 | 6518152 |
| pelvic inflammatory disease after hysterosalpingography associated with chlamydia trachomatis and mycoplasma hominis. | a total of 116 women were referred for hysterosalpingography because of primary or secondary infertility. chlamydia trachomatis was isolated from the cervix of four (3.4%) of the patients whereas mycoplasma hominis was isolated from 39 (33.6%) of them. four patients developed acute pelvic inflammatory disease after hysterosalpingography; two of them were chlamydia culture-positive and developed a significant chlamydial antibody response during the course of the disease. one of the other two pati ... | 1984 | 6518153 |
| introductory address: microbial etiology of pelvic inflammatory disease. | the etiology of acute pelvic inflammatory disease is multifactorial, and the pattern of organisms most frequently causing the condition fluctuates. for example, tuberculous salpingitis has gradually become a rarity in many areas, and cases of nongonococcal salpingitis have started to outnumber those of gonococcal salpingitis. chlamydia trachomatis now causes more cases than neisseria gonorrhoeae in many regions. mycoplasma hominis is another (often overlooked) etiologic agent infection in the up ... | 1984 | 6523323 |
| [experimental magnesium ammonium phosphate lithiasis induced by ureaplasma in the rat]. | struvite urinary stones are commonly associated with infections by urease possessing bacteria (proteus). ureaplasma urealyticum, a genital mycoplasma, is predominantly located in the human genito-urinary tract and produces urease. its possible role in the formation of infection stones was studied in the rat model described by friedlander and braude. struvite bladder stones were produced in 60% of sprague-dawley male rats after infection of ureaplasmas (serotype 1, 2, 3, 7) into the renal medulla ... | 1984 | 6531060 |
| [septicemia caused by mycoplasma hominis]. | a patient with septicemia, caused by mycoplasma hominis was described. data were established for pyeloureteral anomalies in both ureters with disturbed left drainage with hydronephrosis ii--ii stage. mixed flora was isolated from urine--mycoplasma hominis and e. coli. pure culture mycoplasma hominis was isolated from the hemocultures. the patient was favourably affected by metacyclin treatment--600 mg daily. | 1984 | 6531866 |
| etiology of recurrent pregnancy losses and outcome of subsequent pregnancies. | prospective evaluation of 155 couples with two or more consecutive pregnancy losses disclosed uterine morphologic abnormalities in 27%, chromosomal abnormalities in 21 individuals (7.7%, or 15.4% of the couples), and at least one abnormal diagnostic test suggestive of a cause for recurrent pregnancy losses in 106 (68%). a positive test for antinuclear antibody was found in 7.5% of the women, whereas the expected rate in a population of this age is less than 2%. cervical cultures for ureaplasma u ... | 1983 | 6604890 |
| antigens of mycoplasma hominis. | the antigens of mycoplasma hominis have previously been defined by means of functional assays with rabbit antisera and have been found to be predominantly protein. in this study, sera from humans as well as those from rabbits were shown to recognize protein antigens of m. hominis in an enzyme-linked immunosorbent assay (elisa) that depended on antigen-binding capacity rather than biologic function. although the elisa was more independent of the strain of m. hominis used as antigen than was the m ... | 1983 | 6607544 |
| the activity of miokamycin (mom) against chlamydia trachomatis and mycoplasmas in vitro. | the activity of miokamycin, a new macrolide, was investigated against chlamydia trachomatis, ureaplasma urealyticum and mycoplasma hominis, in vitro. miokamycin was found to be similar in activity to doxycycline and erythromycin against chlam. trachomatis and u. urealyticum. against mycopl. hominis, miokamycin had an activity clearly superior to erythromycin. | 1983 | 6608516 |
| nonspecific vaginitis and other genital infections in three clinic populations. | nonspecific vaginitis was present in 37% of 40 patients attending the special urology (sexually transmitted disease) clinic at the victoria general hospital, in 23% of 75 patients attending the family planning clinic, and in 23% of 13 patients attending the prenatal clinic at the grace maternity hospital in halifax, nova scotia. the mean prevalence was 27%. subjective complaints of vaginal odor were significantly associated with nonspecific vaginitis (p less than .001), but symptoms of vaginal d ... | 1983 | 6648745 |
| symposia: mycoplasma hominis--a human pathogen. | | 1983 | 6648751 |
| scalp abscess associated with mycoplasma hominis infection complicating intrapartum monitoring. | | 1983 | 6657503 |
| the prevalence of genital chlamydia trachomatis and mycoplasmal infections during pregnancy in an american indian population. | the epidemiology of cervical infection with chlamydia trachomatis, mycoplasma hominis, and ureaplasma urealyticum among a group of pregnant american indian women was investigated. the prevalences of these microorganisms were 24-30% for c. trachomatis, 50% for m. hominis, and 80% for u. urealyticum. these rates are unusually high for an unselected sample. infection with c. trachomatis was correlated with younger age but not with primigravidity or educational level. neither m. hominis nor u. ureal ... | 1983 | 6665663 |
| chemical composition and ultrastructure of mycoplasma hominis. | mycoplasma hominis belongs to the family mycoplasmataceae, which includes the smallest free-living organisms known to exist. despite the small size of the organism, its chemical composition and cell structure are almost as complex as in other bacteria. the cytoplasm contains typical 70s bacterial ribosomes and a circular double-stranded dna molecule. both of these structures have been well characterized. like other mycoplasmas, m. hominis lacks a cell wall. the cytoplasmic membrane is the outer ... | 1983 | 6665666 |
| biochemistry of mycoplasma hominis. | the growth of mycoplasma hominis is stimulated by arginine. a possible mechanism for degradation of this amino acid is the arginine dihydrolase pathway. the first enzyme of the pathway, arginine deiminase, is inducible in m. hominis. evidence exists that the dihydrolase pathway is not the major pathway to production of adenosine triphosphate in the organism. m. hominis does not take up nucleosides from the growth medium, although the metabolic processes required for the transformation of precurs ... | 1983 | 6665667 |
| evaluation of culture media for the recovery of mycoplasma hominis from the human urogenital tract. | specimens from the cervix or posterior vaginal fornix of 50 women attending a venereal disease clinic and from the urethra of 50 men with nongonococcal urethritis were cultured for mycoplasma hominis. recovery of the organism in two conventional mycoplasma culture media containing horse serum was compared with that in sp-4 broth medium (which is used for the culture of fastidious mycoplasmas). m. hominis was isolated from approximately 63% of the specimens from women by means of either of the ho ... | 1983 | 6665668 |
| epidemiology of mycoplasma hominis. | mycoplasma hominis colonizes the vagina of women and the urethra of men. the organism is also isolated from beneath the foreskin of uncircumcised men. it is sexually transmitted. m. hominis is isolated from a small proportion of children and sexually inexperienced adults. among sexually experienced adults, rates of colonization rise in relation to the lifetime number of sexual partners. even with sexual experience taken into account, the organism is more prevalent among young individuals and amo ... | 1983 | 6665669 |
| the role of mycoplasmas in the upper genital tract of women. | mycoplasma hominis is isolated from the cervix of 10-20% of healthy, fertile women. in contrast, the organism is recovered from the lower genital tract of 50-70% of women with pelvic inflammatory disease. moreover, a significant antibody response to m. hominis is found in one-fourth of all patients with clinical and/or laparoscopic signs of pelvic inflammatory disease. these results suggest that m. hominis is etiologically involved in inflammation in approximately 25% of patients with acute pelv ... | 1983 | 6665670 |
| isolation of mycoplasma hominis and ureaplasma urealyticum from amniotic fluid at 16-20 weeks of gestation: potential effect on outcome of pregnancy. | samples from 61 amniotic fluids (33 discolored and 28 clear) collected by amniocentesis between 16 and 20 weeks gestation were cultured for microorganisms. two of the discolored fluids were positive for mycoplasma hominis, and two were positive for ureaplasma urealyticum. neither organism was isolated from samples of clear amniotic fluids. no other bacteria, viruses, or chlamydiae were isolated from fluids of any patient. the results prove that both m. hominis and u. urealyticum can infect the a ... | 1983 | 6665671 |
| mycoplasma hominis and intrauterine infection in late pregnancy. | amniotic fluid was collected via a transcervical intrauterine catheter from patients with clinical evidence of intrauterine infection and from uninfected comparison patients. the amniotic fluid was cultured for mycoplasma hominis and ureaplasma urealyticum, as well as for aerobic and anaerobic bacteria. two series of patients are reported. in the first, there were 52 patients with intraamniotic infection and 52 matched controls. eighteen patients (35%) with intraamniotic infection and four contr ... | 1983 | 6665672 |
| mycoplasma hominis: a placental pathogen? | current information on the role played by mycoplasma hominis in placental inflammation was reviewed. m. hominis is associated with chorioamnionitis and funisitis, but the clinical significance of this association in not clear. further research on the role of the organism in perinatal disease is needed. meanwhile, in a gravely ill infant with a history of prolonged rupture of the placental membranes, chorioamnionitis, and funisitis, m. hominis should probably be considered a potential pathogen, c ... | 1983 | 6665673 |
| prospective studies of mycoplasma hominis infection in pregnancy. | the prevalence of mycoplasma hominis infection in ten different studies of pregnant women ranged from 7.3% to 50%. it is unclear, however to what extent m. hominis is a pathogen to the mother or fetus. prospective studies have attempted to investigate the role of m. hominis in complications of pregnancy. several have indicated a role for the agent in postpartum fever and endometritis, but only one so far has demonstrated the association in a large-scale sample independent of other suspected path ... | 1983 | 6665674 |
| etiologic role of mycoplasma hominis and ureaplasma urealyticum in women with the acute urethral syndrome. | in an assessment of the possible etiologic role of mycoplasma hominis and ureaplasma urealyticum in the acute urethral syndrome (aus) in women, 79 women with aus, 35 women with acute bacterial cystitis, and 66 asymptomatic volunteers were studied. evidence against an etiologic role for m. hominis in aus included: (1) a similar prevalence of the organism among women with aus (18%), women with cystitis (29%), and asymptomatic women (15%); (2) a lack of association of m. hominis with aus cases for ... | 1983 | 6665675 |
| mycoplasma hominis and interstitial cystitis. | antibodies to mycoplasma hominis were detected by indirect hemagglutination in nine (56%) of 16 patients with chronic interstitial cystitis. in seven patients (44%), titers of greater than or equal to 160 were found. antibodies to ureaplasma urealyticum were detected in three (19%) of these patients; in only one patient was a high titer, i.e., greater than or equal to 160, found. m. hominis was isolated from voided urine of two patients, and u. urealyticum was recovered from the urine of three p ... | 1983 | 6665676 |
| mycoplasma hominis infection of the central nervous system in newborn infants. | the incidence of infections of the central nervous system caused by mycoplasma hominis in newborn infants is not known. however, such infections occur in both full-term and premature infants, either with or without malformations such as myelomeningocele. m. hominis has also been recovered from brain abscesses. infected infants usually present with signs of meningitis or meningoencephalitis. hydrocephalus may develop. the cerebrospinal fluid characteristically has a reduced glucose content and an ... | 1983 | 6665677 |
| mycoplasma hominis: a review of its role as a respiratory tract pathogen of humans. | mycoplasma hominis seldom colonizes the human respiratory tract and only rarely causes acute respiratory infection. it can be recovered from the respiratory secretions of 1-3% of healthy persons and of less than or equal to 8% of persons with chronic respiratory disease, but it has not been implicated definitely in the etiology of this disease or in the exacerbations that characterize its course. m. hominis has been isolated from less than or equal to 6% of persons with acute pharyngitis or acut ... | 1983 | 6665678 |
| organ culture studies with mycoplasma hominis. | organ cultures have been a valuable aid in the study of the interaction of pathogenic microorganisms with differentiated cells in vitro. most studies of mycoplasma hominis in tracheal and fallopian tube organ cultures using conventional light microscopic techniques have been unable to detect any clear cytopathic effects. more recent work, using sophisticated methods to examine the epithelial surface of fallopian tubes in culture, have now revealed alterations in the morphology and function of th ... | 1983 | 6665679 |
| monkey animal model for study of mycoplasmal infections of the urogenital tract. | various experimental monkey models have been used for the study of mycoplasmal infections of the urogenital tract. direct inoculation of mycoplasma hominis and ureaplasma urealyticum into the urethra of male monkeys resulted in successful reisolation of the organisms from the urethra without giving rise to signs of urethritis during the observation period. the organisms were inoculated into the posterior fornix of the vagina of female grivet monkeys. during the ten-week observation period, there ... | 1983 | 6665680 |
| studies on ciliated epithelia of the human genital tract. iv. mucociliary wave activity in organ cultures of human fallopian tubes challenged with mycoplasma hominis. | ciliary activity was studied in specimens of fallopian tube mucosa that were maintained as organ cultures and experimentally infected with mycoplasma hominis. this activity was quantitated by an established method for recording of the light reflexes from the ridges and troughs in the mucous layer in which the cilia are beating. in organ cultures infected with m. hominis, a ciliostatic effect was observed; the proportion of organ cultures with no detectable ciliary activity was higher and the num ... | 1983 | 6665681 |
| tetracycline resistance in mycoplasma hominis. | the composition of the cytoplasmic membrane of a clinical isolate of mycoplasma hominis that was resistant to tetracycline (minimal inhibitory concentration, 30 micrograms/ml) was compared with that of a susceptible strain (minimal inhibitory concentration, less than 1 microgram/ml). neither differences in passive permeability of the lipid portion of the membrane to the drug nor modulation of active transport by membrane lipids explained the resistance to tetracycline. polyacrylamide gel electro ... | 1983 | 6665682 |
| treatment of extragenital infections caused by mycoplasma hominis. | extragenital infections caused by mycoplasma hominis and the indications for antibiotic treatment of such infections were reviewed. invasion of the bloodstream in conjunction with urologic disease or trauma and metastatic spread of m. hominis to the central nervous system or the joints must be treated with effective drugs. in contrast, m. hominis bacteremia in women with febrile abortion and postpartum fever is often transient and self-limiting and does not generally require treatment. a tetracy ... | 1983 | 6665683 |
| role of mycoplasmas in chronic prostatitis. | in 17 out of 102 patients with clinically diagnosed chronic prostatitis the disease could be attributed to known urogenital tract pathogens. of the remaining 85 patients, ureaplasma urealyticum was isolated from 38, chlamydia trachomatis from five, and both organisms together from two. the results of antimicrobial treatment of the patients suggest an etiological relationship between ureaplasma urealyticum and certain cases of chronic prostatitis. in these cases urethritis seems to be an accompan ... | 1983 | 6679148 |
| role of genital mycoplasmas in nongonococcal urethritis and prostatitis. | the roles of mycoplasma hominis and ureaplasma urealyticum in the pathogenesis of nongonococcal urethritis (ngu) remain controversial. isolation and serologic studies and results of antibiotic therapy do not provide good evidence that m. hominis causes ngu. the results of some studies of therapy and of some experiments in which humans were inoculated with u. urealyticum indicate that this organism may cause some cases of ngu. however, u. urealyticum is ubiquitous and apparently nonpathogenic at ... | 1983 | 6689378 |
| mycoplasma hominis in nonspecific vaginitis. | the prevalence of nonspecific vaginitis was 24% among 98 randomly selected women examined at a clinic for sexually transmitted diseases and 32% among 135 women with suspected cervicitis at the same clinic. mycoplasma hominis was isolated more often and serum antibody levels to m. hominis were higher in women with nonspecific vaginitis than in women without nonspecific vaginitis. similarly, the rate of isolation of gardnerella vaginalis and the quantitative growth of g. vaginalis were higher for ... | 1983 | 6689379 |
| mycoplasma hominis in cervicitis and endometritis. | the presence of serum igg antibody to mycoplasma hominis was studied by enzyme immunoassay in 150 women with suspected cervicitis at a clinic for sexually transmitted diseases. positive levels of antibody were associated with gravidity and parity but not with age, method of birth control, or sexual behavior. women from whom m. hominis was isolated had higher antibody levels than those from whom m. hominis was not isolated, regardless of the presence or absence of mucopurulent cervicitis. in wome ... | 1983 | 6689380 |
| isolation of mycoplasma hominis from genital ulcerations of patients in eastern and southern africa. | in three separate surveys involving 413 patients in mbabane (swaziland), nairobi (kenya), and carletonville (south africa), mycoplasma hominis was isolated from the base of ulcers in 41 (16%) of 251 men with genital ulcer disease. antibodies to m. hominis were detected by indirect hemagglutination in 89 (51%) of 176 such patients. of these male patients, 15% and 6% had indirect hemagglutinating antibodies at titers of greater than or equal to 160 and greater than or equal to 640, respectively. t ... | 1983 | 6689381 |
| the association of mycoplasma hominis with arthritis. | the facts that mycoplasmal arthritis occurs naturally in various animal species and can be induced experimentally have been the main reasons for searching for evidence of mycoplasmal infection in the joints of patients with rheumatoid arthritis. there is, however, no evidence that mycoplasma hominis is involved in this disease. on the other hand, m. hominis and other mycoplasmas, including ureaplasma urealyticum, have been isolated from the arthritic joints of several hypogammaglobulinemic patie ... | 1983 | 6689382 |
| lack of association between genital mycoplasmas and infertility. | we studied the relation between colonization with mycoplasma hominis and ureaplasma urealyticum, and the results of infertility studies in 205 women with involuntary infertility of at least one year's duration. isolation of m. hominis (but not of u. urealyticum) was significantly (p = 0.002) more common in patients with a history of pelvic inflammatory disease. however, no relation could be shown between these genital mycoplasmas and any of the following: evidence of prior pelvic inflammatory di ... | 1984 | 6700691 |
| the importance and frequency of mixed infections with chlamydia trachomatis and mycoplasmas in acute gonococcal urethritis. | chlamydia trachomatis, ureaplasma urealyticum and mycoplasma hominis are frequently involved in gonococcal urethritis. we investigated 143 male white and black patients with gonococcal urethritis (average age 22,5 years). of these 29% had coexisting chlam. trachomatis infection, 34% u. urealyticum infection and 13% mycoplasma hominis infection. conventional penicillin therapy did not affect chlam. trachomatis, u. urealyticum or mycoplasma hominis, which persisted in the lower urogenital tract, c ... | 1984 | 6701710 |
| mycoplasma infections of the human urogenital tract with particular reference to non-gonococcal urethritis. | the criteria which need to be fulfilled before regarding a microorganism as a cause of non-gonococcal urethritis (ngu) are considered in relation to mycoplasma hominis, ureaplasma urealyticum and m. genitalium. there is no evidence to support an aetiological role for m. hominis, but few appropriate investigations have been undertaken. the criteria have been met, for the most part, in the case of u. urealyticum, but further quantitative studies are required. the role of m. genitalium is unknown, ... | 1984 | 6712055 |
| in vitro activity of clindamycin against strains of chlamydia trachomatis, mycoplasma hominis, and ureaplasma urealyticum isolated from pregnant women. | chlamydia trachomatis, mycoplasma hominis, and ureaplasma urealyticum are genital agents that are being increasingly implicated in infectious pregnancy complications and abnormal pregnancy outcomes. we measured the in vitro activity of clindamycin against strains of these three agents which were isolated from pregnant women. for 30 strains of c. trachomatis, the median minimal inhibitory concentration was 1.0 microgram/ml (range, 0.25 to 2.0 micrograms/ml). for 27 strains of m. hominis, the medi ... | 1984 | 6742014 |
| peritonitis due to mycoplasma hominis in a renal transplant recipient. | | 1982 | 6752300 |
| the microbiology and therapy of acute pelvic inflammatory disease in hospitalized patients. | we examined microbial isolates from the endocervical and peritoneal cavity of 30 women hospitalized with acute pid. patients were randomly assigned to one of two antibiotic regimens: amoxicillin, 6 gm by mouth every 24 hours, or aqueous penicillin g, 30 million units and gentamicin, 180 to 240 mg intravenously every 24 hours. we measured response by quantifying physical examination findings. neisseria gonorrhoeae was isolated from the cervix of 24 patients (80%) and from the peritoneal cavity of ... | 1980 | 6766274 |
| sexually transmitted conditions among women college students. | we studied 500 unselected young women who consulted a gynecologist in a student health service. most participants were symptom-free and had normal physical examinations. few sexually transmitted infections were encountered. neisseria gonorrhoeae was recovered from two and trichomonas vaginalis was obtained from 14 of 500 women. chlamydia trachomatis was recovered from 20 (4.6%) of 439 participants. genital warts, genital herpes, and molluscum contagiosum, respectively, were noted in seven, four, ... | 1981 | 6779634 |
| antibodies to chlamydia trachomatis, mycoplasma hominis, and neisseria gonorrhoeae in sera from patients with acute salpingitis. | paired sera from 60 consecutive patients with acute salpingitis, confirmed by laparoscopy, were examined for serum antibodies to chlamydia trachomatis, mycoplasma hominis, and neisseria gonorrhoeae. by a microimmunofluorescence (mif) test igm or igg antibodies to c trachomatis or both were present in sera from 80% of the patients' by indirect haemagglutination (iha) tests antibodies to m hominis and n gonorrhoeae pilar antigens were present in 40% and 18% respectively. in a control group of 50 p ... | 1981 | 6783261 |
| attachment of mycoplasma hominis and m. orale to human diploid lung fibroblasts. | the process of attachment of mycoplasma hominis and m. orale to hain-55 cells, derived from normal embryonic human lung, was investigated quantitatively. the attachment reached its maximum within about 2-4 hr at 37 degrees c and increased linearly as a function of the number of organisms present in the system. the relative attachment efficiency of m. hominis was approximately 1% under our experimental conditions. trypsin and edta were effective in detaching particles of m. hominis and m. orale f ... | 1981 | 6793814 |
| association of genital mycoplasmas with exudative vaginitis in a 10 year old: a case of misdiagnosis. | a 10-year-old girl with a 1-year history of lower genitourinary tract symptoms suggestive of bacterial infection but with numerous negative urine cultures was referred to the university of alabama urology clinic after empirical treatment with multiple antibiotics failed to resolve her symptoms. an extensive urologic evaluation revealed no structural or physiologic abnormalities, but an exudative vaginitis was noted and large numbers of ureaplasma urealyticum and mycoplasma hominis were isolated ... | 1983 | 6823429 |
| a controlled study of genital mycoplasmas in amniotic fluid from patients with intra-amniotic infection. | amniotic fluid (af) was collected via a transcervical, intrauterine catheter from 52 patients with clinical intra-amniotic infection (iai) and from 52 matched, uninfected controls. the af was cultured for mycoplasma hominis and ureaplasma urealyticum as well as for aerobic and anaerobic bacteria. eighteen (35%) patients with iai and four (8%) controls had m. hominis in af (p less than 0.001). twenty-six (50%) patients with iai and 26 (50%) control patients had u. urealyticum in af (difference no ... | 1983 | 6842005 |
| studies on the role of ureaplasma urealyticum and mycoplasma hominis in prostatitis. | it has definitely been demonstrated that ureaplasma urealyticum is one etiologic agent of nongonococcal urethritis, a sexually transmitted disease. for this reason it seemed possible that the organisms might cause ascending inflammatory reactions of the prostate. quantitative determinations of ureaplasmas and mycoplasma hominis, together with localization studies, were therefore performed to elucidate the importance of these microorganisms in patients with chronic prostatitis. u. urealyticum was ... | 1983 | 6842018 |
| septicemia due to mycoplasma hominis. | mycoplasma hominis was recovered from the blood of 7 patients with various underlying disorders. one patient had a legal abortion, another a caesarian section, both followed by septicemia. three patients had genital infections in pregnancy, followed by septicemia and spontaneous abortion. m. hominis was also recovered from cervix and urethra in 2 of these women. high serum antibody levels against m. hominis were demonstrated in 3 women. one female developed septicemia after cancer surgery, one m ... | 1983 | 6844881 |
| serologic evidence of ureaplasma urealyticum infection in women with spontaneous pregnancy loss. | among 71 couples with histories of pregnancy wastage, 84.5% were colonized with ureaplasma urealyticum and/or mycoplasma hominis; whereas in couples with successful deliveries the incidence was 25.4%. the distribution of u. urealyticum and m. hominis was comparable in the fertile and infertile populations. of women with positive cultures, 96% aborted, compared with an expected rate of 19% to 45%. serologic studies revealed that, at delivery, 42.9% of infants of mothers with pregnancy losses had ... | 1983 | 6849359 |
| mycoplasma hominis infection of the central nervous system in a neonate. | a newborn infant with group b streptococcal sepsis responded to the intravenous administration of antibiotics within 3 days, but then began to show signs of central nervous system infection. routine cultures of cerebrospinal fluid samples were negative, but others done for mycoplasma hominis yielded that organism. after 3 more days of antibiotic therapy, cultures for m. hominis were negative, and the child's recovery was uneventful. | 1983 | 6871803 |
| septic arthritis due to mycoplasma hominis. | | 1983 | 6882481 |
| cervical chlamydia trachomatis and mycoplasmal infections in pregnancy. epidemiology and outcomes. | in a prospective study of chlamydial and mycoplasmal infections in pregnancy, chlamydia trachomatis occurred in 8.0%, mycoplasma hominis in 23.5%, and ureaplasma urealyticum in 72.3% of 1,365 enrollees. by multivariate analysis, c trachomatis was correlated with lower socioeconomic status, age 23 years or younger, and 12 years or less of schooling. ureaplasma urealyticum was correlated with age 23 years or younger and lower socioeconomic status. mycoplasma hominis was correlated with more than o ... | 1983 | 6887487 |
| follicular cervicitis--colposcopic appearances and association with chlamydia trachomatis. | follicular cervicitis was recognised in 15 (44 per cent) of 34 women who were examined colposcopically and who were sexual partners of men with non-gonococcal urethritis. valid results of culture for chlamydia trachomatis were obtained in 26 cases: the organism was isolated from the cervix of five of 11 women in whom follicular cervicitis had been diagnosed, but from only one of 15 whose cervices did not have this change. a similar correlation was not found for infection with mycoplasma hominis ... | 1981 | 6893939 |
| three years' experience of sexually transmitted diseases in seville, spain. | at present there are no reliable statistics on the relative prevalences of sexually transmitted diseases (stds) in spain. in a report of the first three years' experience in an std diagnostic centre between 1977 and 1979 a total of 879 patients (534 men adn 345 women) were seen. they mainly consisted of university students and the mean age was 22 years in 1977 and 23 years in the following two years. all the patients were examined for syphilis and all women for gonorrhoea and trichomoniasis. inv ... | 1981 | 6894560 |
| treatment of acute salpingitis--with special reference to chlamydia trachomatis. | conservative treatment of acute salpingitis should be the rule, surgery the exception. neisseria gonorrhoeae, chlamydia trachomatis, and mycoplasma hominis, are common etiological agents in pelvic inflammatory disease, particularly in women below the age of 25 years. in women above that age as well as in those with two or more episodes of acute salpingitis, there is a higher proportion of tubal infections caused by aerobic and facultatively anaerobic bacteria. apart from some resistant strains, ... | 1982 | 6958017 |
| premature labor. ii. bacterial sources of phospholipase. | human term labor is thought to be initiated by amniotic and chorionic phospholipase a2, an enzyme that liberates arachidonic acid esters from the phospholipids of these membranes, leading to the synthesis of prostaglandins by the placental membranes. the striking association of premature labor with intrauterine infection or contamination, urinary tract infection, and early neonatal sepsis led us to study the microorganisms present in these infections for phospholipase a2 activity. activity was f ... | 1981 | 7017516 |
| comparison of serological tests for detection of mycoplasma hominis antibodies in female grivet monkeys with experimentally induced salpingitis. | four serological tests, viz. indirect hemagglutination (iha), metabolism inhibition (mi), immunofluorescence (imf), and a modification of the growth-inhibition (gi) test have been compared for the detection of antibodies against mycoplasma hominis in female grivet monkeys with experimentally induced pelvic inflammatory disease. moreover, cold hemagglutinins (cha), and immunoglobulins, m, g, and a have been determined. the iha test was found to be superior to the other methods used. the antibodie ... | 1981 | 7020337 |
| clinical and microbiological study of non-gonococcal urethritis with particular reference to non-chlamydial disease. | a double-blind placebo-controlled study of minocycline in 221 men with non-gonococcal urethritis (ngu) was undertaken. techniques were used which enabled diagnoses of chlamydial and mycoplasmal infections to be made within 24 hours of a patient attending a clinic. all patients from whom chlamydia trachomatis was isolated were treated with minocycline, while patients from whom ureaplasma urealyticum or mycoplasma hominis was isolated, or from whom no micro-organisms were isolated, were treated on ... | 1981 | 7028208 |
| aetiology and management of non-specific vaginitis. | in a study of 100 women with non-specific vaginitis, characterised by a vaginal discharge which was malodorous and pruritic in most cases and caused dyspareunia and dysuria in some, gardnerella vaginalis was isolated in 46% of patients. when present, g vaginalis was significantly associated with mycoplasma hominis and bacteroides species. isolation of g vaginalis was unrelated to the presenting symptoms. treatment with povidone-iodine pessaries for two weeks produced no pronounced benefit, eithe ... | 1982 | 7034858 |
| isolation of mycoplasma hominis from the blood of men with multiple trauma and fever. | | 1982 | 7053444 |
| massive pericardial effusion due to mycoplasma hominis in a newborn. | | 1982 | 7064954 |
| late spontaneous abortion associated with mycoplasma hominis infection of the fetus. | a 35-year-old gravida 4 was admitted in pregnancy week 25 because of premature rupture of the fetal membranes. two days later an intra-uterine infection developed. treatment with clindamycin and ampicillin was started. however, she aborted within a few hours. the fetus was of normal size and without malformations. mycoplasma hominis could be isolated from the placenta, cerebrospinal fluid and lungs of the fetus during sterile autopsy, and also from the genital tract of the patient, who had a hig ... | 1982 | 7071530 |
| evidence for an association between chlamydia trachomatis and cervical intraepithelial neoplasia. | attempts were made to isolate chlamydia trachomatis, mycoplasma hominis and ureaplasma urealyticum from women with cervical intraepithelial neoplasia (cin), from those with microinvasive or invasive cervical cancer, and from a control group of similar women with other gynaecological problems. c. trachomatis was found in a significantly greater proportion of women with cin (8%) or cervical cancer (18%) than in the control group (1%), whereas m. hominis and u. urealyticum were approximately as com ... | 1982 | 7082604 |
| isolation and preliminary characterisation of mycoplasmavirus 20-p. | a mycoplasmavirus, mv 20-p, was isolated from the fastidious, slow-growing human mycoplasma 20-p, previously identified by the growth inhibition test as mycoplasma hominis type 2. its broth culture was ultracentrifuged into 35% saccharose, the pellet was resuspensed in buffer, and the suspension was dropped onto laws of the virus indicator acholeplasma laidlawii bcl-13. the virus was washed off the plaque areas by buffer. mv 20-p appeared in electron microscopy as spherical, enveloped particles ... | 1982 | 7098542 |
| [etiological role of mycoplasma hominis in inflammatory diseases of the urogenital tract in pregnant and nonpregnant women]. | | 1982 | 7102971 |
| [studies on the aetiology of non-gonococcal urethritis (author's transl)]. | tests performed on urethral secretion and morning urine specimen identified the causative micro-organism in 143 of 164 males with non-gonococcal urethritis. in 59 patients (36%) there was an infection with chlamydia trachomatis, in 48 (29.2%) with ureaplasma urealyticum in significantly high bacterial counts (greater than or equal to 10(4) kbu/ml) urethral secretion (greater than or equal to 10(3) kbu/ml first urine sample), and in a further 18 patients (11%) double infections with chlamydia tra ... | 1982 | 7106003 |
| mycoplasma hominis septicemia. | we report a case of mycoplasma hominis septicemia in a patient with chronic lymphocytic leukemia and prostatic obstruction. signs of sepsis followed urinary catheterization, and m. hominis was recovered repeatedly from blood, urine, and pleural fluid. detection in blood was accomplished by routine subculture from grossly negative blood culture bottles. | 1982 | 7130369 |
| attempts to detect by physicochemical methods plasmid dna in mycoplasmas of human origin before and after transformation to tetracycline resistance. | physicochemical methods have been used to compare mycoplasma dna capable of the genetic transformation of tetracycline resistance with dna from tetracycline-sensitive mycoplasmas and their transformants. these mycoplasmas were isolated from human patients. the dna extracted from mycoplasma hominis tetr resistant to 100 microgram/ml tetracycline transforms tetracycline resistance to sensitive strains of mycoplasma salivarium tets and mycoplasma hominis tets but not mycoplasma fermentans tets. bul ... | 1982 | 7139411 |
| comparison of two methods for enumeration of mycoplasmas. | two methods of viable cell counts were evaluated for mycoplasma hominis and ureaplasma urealyticum: color change unit50 and colony-forming unit. the color change unit50 method gave higher estimates of cell numbers; furthermore, the color change unit50 values correlated better with the dna content of the cell pellet and the published genome sizes. | 1982 | 7153345 |
| [mycoplasma hominis and spontaneous abortion]. | | 1982 | 7168470 |