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sputum induction by saline aerosol.a simple technique for inducing sputum production with vaporized 15% aqueous nacl is described. fifteen inhalations of saline aerosol, followed by a waiting period of 15-30 minutes, were sufficient to induce a productive cough in 93% of the persons tested. the apparatus is portable, cheap, easily maintained and suitable for use under field or hospital conditions.1977403619
[secondary drug resistance of mycobacterium tuberculosis in patients with chronic destructive forms of pulmonary tuberculosis]. 1977403681
comparative analysis of the antigens of m. tuberculosis h37rv with various mycobacterial antigens.comparative immunoelectrophoretic and immunodiffusion analyses have indicated that h37rv shares a number of antigens with other mycobacteria. some of these shared antigens are polysaccharide in nature wheras others are proteins. the two antigens that this organism shares with m. smegmatis are primarily polysaccharides and so is the antigen that it shares with bcg ribosomal fraction. with m. kansasii, the h36rv shares both polysaccharide and protein antigens, the polysaccharide antigens being the ...1977403715
specific in vitro lymphocyte response of chickens injected with killed mycobacterium tuberculosis.an in vitro microassay for lymphocyte transformation, using 3h-thymidine incorporated into avian peripheral blood leukocytes, is described. the transformation responses of 1 x 10(6) leukocytes stimulated by the nonspecific mitogen, phytohemagglutinin-m (pha-m), were equivalent with 68- and 92-hour incubation durations. the pha-m in concentration of 50 micronl/ml produced greater stimulation than did that of 25 or 100 micronl/ml. the transformation response to pha-m was significantly affected by ...1977403836
mycobacterial antigens relating to experimental pulmonary cavity formation.lipid-protein mixtures were obtained from 2 strains of mycobacteria, and their cavity-forming activities were examined in rabbit lungs. the mixtures were separated into lipid and protein fractions by gel filtration on sephadex lh-20 column. neither lipid nor protein fraction alone had cavity-forming activity; however, restoration of the cavity-forming activity was observed by recombining the fractions. the activity was also reconstructed by combining the protein fraction with cell walls of bacil ...1977403839
[an immunological enhancement phenomenon in different experimental bacterial infections].to demonstrate that an enhancement phenomenon might be involved during the development of bacterial infections, one has to establish that specific humoral antibodies protect, in some way, microorganisms against the defence reations of the host. this report presents the evidence that specific antibodies could be evolved in assuming a certain survival of bacterial cells in host's tissue. (1) homologues antistaphylococcal sera passively potentiated the development of experimental staphylococcal syn ...1977403848
lack of protection afforded by ribonucleic acid preparations from mycobacterium tuberculosis against mycobacterium leprae infections in mice.mycobacterial ribonucleic acid preparations from h37ra, an attenuated strain of mycobacterium tuberculosis, provide their usual marked protection against m. tuberculosis challenge; however, they provided no protection against mycobacterium leprae challenge. suspensions of intact h37ra were not effective against m. leprae. suspensions of bcg gave their usual distinct protection against m. leprae challenge.1977404242
metabolic role of free mycolic acids in mycobacterium tuberculosis.small amounts of free mycolic acids and trehalose dimycolate that are rapidly formed by mycobacterium tuberculosis h37ra are probably derived from mycolyl acetyl trehalose and transferred to the cell wall. however, the transfer of mycolic acids from mycolyl acetyl trehalose to the cell wall still appears to be the more prominent route.1977404289
smear results in the diagnosis of mycobacterioses using blue light fluorescence microscopy.examination of 6,880 sputum specimens from untreated patients disclosed that 3.1% were positive for mycobacteria by fluorescence microscopy, and 92.5% of these has positive cultures. there was a positive correlation between the number of organisms seen on smear and growth on culture. all specimens with positive smears and negative cultures contained rare or few acid-fast bacilli on the smear. eighty-two percent of the specimens with positive cultures and negative smears yielded less than 25 colo ...1977404313
loss of hextuple resistance to aminoglycoside antibiotics in mycobacterium tuberculosis (h37rv) by mutation to isoniazid resistance and by incubation at high temperature. 1977404392
relationship between multicentric reticulohistiocytosis and tuberculosis.some cases presently classified as multicentric reticulohistiocytosis may represent unusual manifestations of tuberculosis. antituberculous chemotherapy may be justified in patients who have clinical and histopathologic evidence of multicentric reticulohistiocytosis in association with a positive tuberculin skin test.1977404438
[cross-resistance of tubercle bacilli. (a review ii) (author's transl)]. 1977404456
[action mechanism of antitubercular agents]. 1977404457
mitogenic activity of cell-wall components in mouse spleen cells. 1977404503
[the results in our tuberculosis laboratory with penicillin blood agar medium].a comparison of löwenstein - jensen and penicillin blood agar media, which can be prepared in small laboratories, is made in routine diagnostic cultivations of mycobacterium tuberculosis. tuberculosis. tubercle bacilli grown in löwenstein - jensen medium were inoculated in löwenstein - jensen and penicillin blood agar media in numbers of 100.000, 10.000, 1000 and 100 bacilli and their growth was detected in each medium. it was found that the growth in both media was the same inoculations were ma ...1977404514
[primary cutaneous tuberculosis complex as an imported disease]. 1977404577
studies on pyrazine derivatives. part vii. synthesis and tuberculostatic activity of some pyrazine amidines and amidoximes.in the reaction of 2-cyano-6-alkylaminopyrazines with sec. amines in the presence of anhyd. alcl3 amidines 1-13 were obtained. from pyrazine-2-imidoesters, 2-cyano-pyrazines and pyrazine-2-carbothioamides and hydroxylamine, amidoximes 14-49 were easily prepared. these new compounds were, however, of little tuberculostatic activity (mic between 31.5-2000 mug/cm3).1977404633
derivatives of 4(7)-methyl- and 5,6-dimethyl-benzimidazolyl-2-mercaptoacetic acids.esters, hydrazides and hydrazones of the in title mentioned acids were prepared and screened for tuberculostatic activity. the strongest activity (mic at 15-6 mug/cm3) was shown by hydrazide 4 and its hydrazone 4a.1977404634
[contemporary treatment of skin tuberculosis]. 1977404674
[antitumor resistance in depositing mycobacterium tuberculosis in the lungs of rats].in the experiments on rats of "wistar" line and non-inbred rats the author has demonstrated that the inflammatory process in the lungs induced by non-virulent mycobacteria of bcg strain is able to decrease the organism resistance to the occurrence of chemically induced tumors. desensibilization with ppd prior to the appearance of tumors would contribute to restoration of their antitumor resistance.1977404765
[intracellular activity and phagocytability of freshly-isolated strains as parameters of the pathogenicity of tuberculosis mycobacteria].phagocytability and the capacity of intracellular multiplication of mycobacteria tuberculosis isolated from the patients before the treatment and during it (in 1-5 months and later) were studied in the culture of normal peritoneal guinea pig macrophages. a method of quantitative assessment of the capacity to intracellular reproduction of mycobacteria tuberculosis by determination of the relative activity index in comparison with the standard strain was elaborated. all the cultures of mycobacteri ...1977404811
the influence of a history of a previous test on the prevalence and size of reactions to tuberculin.ten millimeters of more of induration to the mantoux tuberculin test indicates present or past infection with mycobacterium tuberculosis in the overwhelming majority of cases. because a number of patients gave a history of a previous positive reaction that was not confirmed on retesting, we carefully evaluated, as part of a large tuberculin testing survey, 1,428 persons who claimed to have had a previous positive test. of these, 606 (42.4 per cent) had a positive reaction on retesting. when comp ...1977404946
evaluation of a serological test for tuberculosis.the agglutination test of nicholls was found to be ineffective in diagnosing active tuberculosis. a positive result (titre of 1/125 or more) was found in the serum of 74 (70%) out of 105 patients with newly diagnosed, smear-positive pulmonary tuberculosis; 61 (62%) out of 98 healthy family contacts; and 19 (63%) out of 30 patients with non-tuberculous conditions. these findings were not due to faulty technique since the results obtained at hammersmith were similar to those obtained by nicholls's ...1977405075
[effect of trauma upon origin and development of osteoarticular tuberculosis (author's transl)]. 1977405086
panic-fear: a personality dimension related to length of hospitalization in respiratory illness. 1977405367
[improvement in bacteriologic methods of study for the purpose of early detection of tuberculosis carriers]. 1977405556
[results of therapy of early diagnosed patients with focal and infiltrative tuberculosis of the lungs]. 1977405664
[intracellular activity of mycobacteria in patients with pulmonary tuberculosis undergoing chemotherapy]. 1977405665
[method of vertical diffusion in determining bacteriostatic activity of the blood]. 1977405666
in vitro anti-mycobacterial activity of some new amino-glycoside antibiotics.four new aminoglycoside antibiotics, namely gentamycin, amikacin, tobramycin and sisiomycin were tested against several pathogenic strains of so-called 'typical' and 'atypical' mycobacteria. only amikacin exhibited considerable in vitro anti-mycobacterial activity against mycobacterium tuberculosis and not against other mycobacterial pathogens. none of the other three antibiotics exhibited activity against any of the mycobacteria at low concentrations.1977405778
[final disinfection in tuberculosis]. 1977405799
[new aspects in the control of tuberculosis in gdr (author's transl)].the development of the epidemiology of tuberculosis in gdr from 1949 is evaluated. the factors deeply influencing incidence and prevalence of tuberculosis in gdr are: the socioeconomic development of a socialist society with continuous increase of living standard and social fonds, the state of the socialist public health system in general, and the special services and methods for the control of tuberculosis in the chest clinics and hospitals. tuberculosis is no more a common disease in gdr. tube ...1977405808
[the different inactivation of isoniazid in intermittent chemotherapy (author's transl)].a ratio-test (isoniazid: acetyl-isoniazid) is used for phenotyping the isoniazid-inactivation. the border-line between both the phenotypes is determinated. the influence of age and weight of the patients is studied. usefully results are obtained after application per os of an uniform dosage and a sampling period for urine of 4 hours. increasing the dosage to 900 mg the portion of isoniazid arises mmore than proportionally, more distinct in rapid than in slow inactivators. therefore the differenc ...1977405809
[l forms of bacteria of the family mycoplasmataceae and the problem of microbial persistence]. 1977405826
stimulation of macrophages by cord factor and by heat-killed and living bcg.trehalose-6,6'-dimycolate (cord factor; cf) injected into the peritoneal cavity of mice induced stimulation of the peritoneal macrophages, evidenced both by increased activity of the lysosomal enzyme, acid phosphatase, and by increased phagocytosis of listeria monocytogenes. the increase in enzyme activity and phagocytosis was similar to that induced by killed or living bcg. when administered intravenously, cf or bcg did not induce stimulation of peritoneal macrophages. cf when added to tissue c ...1977406198
tuberculosis in the intensive care unit.the overwhelming majority of patients infected with tuberculosis may be very adequately treated without hospitalization on an out-patient basis. until tuberculosis is completely eradicated, however, some patients with extensive disease will require hospitalization for diagnosis and the institution of appropriate chemotherapy. a minority of these who are desperately ill and require admission to an intensive care unit may still recover by the prompt diagnosis of the illness, appropriate supportive ...1977406224
mycobacteria isolated from exotic animals.mycobacteria were isolated from 263 of 474 specimens submitted from captive exotic (nondomesticated) animals over a 5-year period. mycobacterium avium was isolated from 128 animals originating in 13 states and the district of columbia; serotype 1 accounted for 65 of the isolations. mycobacterium bovi was isolated from 74 animals in 7 zoos, 7 game parks, and 4 primate colonies in 1, states: mycobacterium tuberculosis was isolated from 29 animals originating 9 stats; and mycobacterium fortuitum, m ...1977406254
miliary tuberculosis with unusual cutaneous manifestations. 1977406429
[microbiological studies in tuberculosis]. 1977406494
the adjuvant active fraction of delipidated mycobacteria. 1977406575
[interaction of antitubercular agents. i. combined action of rifampicin, isonicotinic acid hydrazide, streptomycin and para-aminosalicylic acid on the growth of strains of tubercle bacilli]. 1977406600
[immunologic reactivity of children and adolescents with tuberculosis according to the study of specific antibodies and immunoglobulins]. 1977406610
[significance of determination of antibodies to mycobacterial nucleoproteins in tuberculosis]. 1977406611
[role of antituberculous antibodies to several chemical substances of the causative agent]. 1977406612
[action of isoniazid and rifampicin on viability and ultrastructure of m. tuberculosis]. 1977406613
[influence of proteolytic enzymes on the mycobacteria and staphylococcus aureus and on their drug resistance]. 1977406614
[types of mycobacteria and incidence of tuberculosis]. 1977406615
occult tuberculous infection in children.three hundred and fifty new zealand children with occult tuberculous infection are reviewed. ninety four had received bcg vaccine previously. three hundred and forty were admitted to hospital and 3 gastric aspirations were obtained from each child and cultured for tubercle bacilli. mycobacterium tuberculosis was isolated from 1 or more aspirates in 29 (8.5%) of the children. excluding those who had received bcg the isolation rate was 10.9%. mycobacterium bovis was not cultured from any child. x- ...1977406702
polyphosphate-glucose phosphotransferase. purification of mycobacterium tuberculosis h37ra enzyme to apparent homogeneity.1. the enzyme (ec 2.7.1.63) was isolated from glucose-grown m. tuberculosis h37ra; during the purification procedure, 2-mercaptoethanol, glucose, edta and nacl served as protecting agents. 2. the enzyme was purified about 600-fold. the preparation was homogeneous on polyacrylamide-gel electrophoresis and gave one precipitin line in double immunodiffusion test. molecular weight of the enzyme determined by sephadex g-100 filtration was about 118 000. 3. the enzyme preparation showed also glucokina ...1977406755
structure of mycobacterial bis-cyclopropane mycolates by mass spectrometry.methyl mycolate from a human strain (brévannes) of mycobacterium tuberculosis has been converted to the corresponding methyl neromycolate, the monketo-meromycolate, and the meromycolic pyrrolidide. the fragmentation pattern of each of these materials has been determined, and with information from a synthetic meromycolate serving as a basis of comparison, has been analyzed to obtain reliable structural assignments.1977407013
approaches to the validation of animal test systems for assay of protective potency of bcg vaccines.three animal test systems, two in guinea-pigs and one in mice, have been examined to differentiate the ability of three bcg vaccines with respect to their ability to protect the animals against infection when challenged with virulent bacilli. one test system showed great promise and was examined in greater detail in order to explain the mechanism of protection. these studies are continuing in order to test a series of bcg vaccines that will be given to groups of children and their protective eff ...1977407231
transtracheal aspiration in diagnosis of sputum-smear--negative tuberculosis.of 4,200 patients admitted to an acute-care county hospital, 126 (3%) were proved to have pulmonary tuberculosis, among whom 35 (28%) had several sputum smears negative for acid-fast bacilli. on transtracheal aspiration, 31 to 35 had acid-fast bacilli in the aspirate. eighteen of these 35 (51%) patients had associated infections caused by aerobic or anaerobic bacteria. tuberculin skin tests were negative in 14 of 35 patients with negative sputum specimens (40%). ten of 18 patients (56%) with ass ...1977407374
tuberculosis bacteriologic reliability. sputum specimens submitted by mail.the reliability of examining mailed specimens of sputum for tubercle bacilli was studied by dividing 132 sputum specimens. one half of each specimen was examined on the same day as collection (fresh); the other half was examined after a delay of from one to eight days (mailed). there were a few discrepancies, but no advantage was shown for use of the fresh portion of the specimens. the rate of contamination was slightly greater in the mailed portions (6.6%).1977407376
[reduction of some new tetrazolium salts containing heterocyclic compounds at their 5-position by myobacteria (author's transl)]. 1977407390
[experimental studies in vitro on the antituberculous activities of tuberactinomycin (tum) and tuberactinomycin-n (tum-n) (author's transl)]. 1977407391
[morphological and microbiological comparisons in pulmonary tuberculosis]. 1977407573
[changes of serological reactions in experimental tuberculosis in animals with diverse resistance]. 1977407574
the effects of metiamide on cell-mediated immune reactions in the guinea-pig.1 the effects of the h2-receptor antagonist, metiamide, on two types of cell-mediated immune response in vivo was investigated in the guinea-pig, in a test of the hypothesis that h2-receptor antagonists would result in 'runaway' unregulated hypersensitivity reactions. 2 metiamide in doses of 5 mg-125 mg/kg given by 6-hourly injection during sensitization and challenge did not modify the delayed hypersensitivity reaction to tuberculin. 3 metiamide in doses of 25-125 mg/kg given by injection, 6-ho ...1977407961
antibodies against bcg antigen 60 in mycobacterial infection.a sensitive specific radioimmunoassay was developed to measure antibodies against bcg antigen 60, a prominent antigenic component of bcg bacilli which cross-reacts with similar components in many mycobacterial species including mycobacterium leprae and m tuberculosis. a lepromatous serum pool had anti-bcg-60 activity with a titre of 10(5) and the tuberculoid pool a titre of 10(4). testing of individual sera showed striking variations within groups of patients with lepromatous and tuberculoid lep ...1977407965
[enzymatic differences in mycobacteria. ribitol dehydrogenase].contrary to the tubercle bacilli (h37ra, bcg), mycobacterium phlei has a ribitol-nad dehydrogenase (that also oxidizes, although to a lesser extent, erythritol and glycerol). this difference is observed with the bacteria grown on sauton's medium, as well as after their adaptation to ribitol. the extracts of all these mycobacteria reduce, nadp in the presence of glycerol, ribitol or erythritol, though very slowly.1977408036
the spectrum of tuberculous peritonitis.from 1966 to 1973, a total of 30 cases of tuberculous peritonitis were seen in seattle-king county. abdominal pain, swelling, and constitutional symptoms were the most frequent initial complaints. radiographic abnormalities consistent with tuberculosis were present in 25 cases, and pulmonary disease was proven in ten. an initial tuberculin test with intermediate-strength purified protein derivative of tuberculin was negative in 19 of 27 patients. six of 13 initial nonreactors still had negative ...1977408103
preservation of mycobacteria st -70 degrees c: persistence of key differential features.the advantages of long-term preservation of suspensions of mycobacteria by storage at -70 degrees c established in earlier studies are reinforced by present evidence that freezer storage does not alter key taxonomic features used to identify mycobacteria. occasional discrepancies in biochemical test characteristics of mycobacteria that have been stored in the freezer and reconstituted at 37 degrees c reflect only sluggish metabolic activity, which is restored to normal on repeat testing.1977408373
effects of the combination of tumor-specific and nonspecific immunization on tumor suppression.the crushed whole aoyama b cells attached to oil droplets were found to be most suitable for the adjuvant effect of mycobacterium tuberculosis against tumor growth when judged by the criterion of effectiveness and a clinical application with minimal side effects. the immunogenicity of tumor cells was well stabilized and maintained with a suitable concentration of formalin; this was less than 1% and the optimum concentration was 0.05% or 0.1%. when the tumor cells treated with the optimum concent ...1977408563
[research in the campaign against leprosy (author's transl)]."leprosy relief through leprosy research" means that the results of research are made available for curing and eradicating the disease. the "marinum model" and the "planter test in mice" are, along with determination of serum activity in healthy test subjects, part of a complex of experiments for the assessment of the therapeutic value of an antimycobacterial substance. this replaces the "controlled studies" which, in their proper form, are scarcely possible for leprosy. with the recently develo ...1977408667
[the frequency of primary drug resistance in tuberculosis in the federal republic of germany including berlin (west) during 1972 to 1975 (author's transl)]. 1977408808
[experimental and clinical evaluation of the diagnostic significance of sensitins]. 1977408809
[antituberculosis antibodies to 3 chemical substances from the causative agent in tuberculosis patients]. 1977408810
[possibilities and value in the drug therapy of tuberculosis]. 1977408982
[the use of purified lipopolysaccharides for serological diagnosis of tuberculosis]. 1977408987
[combination of equipment for partial automation of dosage processes in the bacteriological laboratory]. 1977408990
separation of the mixture of trehalose 6,6'-dimycolates comprising the mycobacterial glycolipid fraction, "p3". 1977409398
mast cell response during the early phase of tuberculosis: an electron-microscopic study.guinea pig lungs were infected with mycobacterium tuberculosis by intratracheal route and examined under electron microscope to investigate the morphological alterations of the organisms, if any, and the response of the host tissue. the bacilli showed no changes in their morphology, while the host tissues revealed several cells containing many electron-dense intracytoplasmic granules. these cells were predominantly seen during the 1st week of infection. the electron-dense bodies of these cells m ...1977409468
macrophage-lymphocyte clusters in the immune response to soluble protein antigen in vitro. iv. synergy of lymphocytes in the formation of clusters. 1977409505
macrophage-lymphocyte clusters in the immune response to soluble protein antigen in vitro. v. inhibition of macromolecular synthesis and of microfilament and microtubule function. 1977409506
synchronized replication of mycobacterium tuberculosis.when mycobacterium tuberculosis was grown in tween-albumin broth without any agitation, the bacilli replicated in the upper, oxygen-rich portion of the medium at a rate that was just balanced by the rate at which the bacilli settled toward the bottom of the tube. when the organisms that accumulated in the sediment were suspended and diluted into fresh medium, they exhibited synchronous replication. the bacilli initiated ribonucleic acid synthesis immediately upon suspension, but marked deoxyribo ...1977409675
impairment of cell-mediated immune responses by infection with mycobacterium lepraemurium.the effect of chronic infection with mycobacterium lepraemurium upon cell-mediated immune responses was studied in lewis rats. rats infected for 40 to 175 days were completely protected from attempted induction of experimental adjuvant disease, and the severity of experimental allergic encephalomyelitis in leprous rats was markedly attenuated. full manifestations of each autoimmune disease were expressed in littermate control groups. skin homograft rejection by infected rats was significantly im ...1977409683
host-parasite relationships in experimental airborne tuberculosis. vi. influence of vaccination with bacille calmette-guérin on the onset and/or extent of hematogenous dissemination of virulent mycobacterium tuberculosis to the lungs.guinea pigs vaccinated with bacille calmette-guérin (bcg) and unvaccinated guinea pigs were challenged by the respiratory route six weeks or six months after vaccination and sacrificed at various intervals after challenge. the six lobes of the lung were cultured separately, and the percentage of culture-positive lobes was calculated, as well as the log10 number of virulent bacilli recovered. the latter was subjected to an analysis of variance, which compared the fate of bacilli in the four large ...1977409784
the relationship between the chemical structure of fatty acids and their mycobactericidal activity.the bactericidal activity of long-chain fatty acids on mycobacteria was examined by exposing the organisms to these acids at 0.04 mm in 0.05 m acetate buffer (ph 5.6). the lethal effect of saturated fatty acids was related to the chain-length of hydrocarbon, c14:0 being the strongest in the activity and longer and shorter fatty acids being less active. unsaturation, isomerism and the presence of alpha-hydroxy group were found to be other factors governing the activity. the lethal effect was grea ...1977409867
effects of cortisone-treatment on experimental mouse infection with pathogenic and saprophytic mycobacteria. 1977409870
[changes in the indication of surgical treatment for pulmonary tuberculosis in accordance with the introduction of rifampicin based on bacteriological findings on culture of resected specimens (author's transl)]. 1977409871
biochemical mechanism of kanamycin resistance in mycobacterium tuberculosis. 1977409905
[effect of nitrofuran and quinoline agents on some biochemical mechanisms of suppressing the viability of mycobacterium tuberculosis]. 1977410014
[demonstration of specific allergens in the sputum as a method of detecting bacillary excretion]. 1977410015
[isolation and identification of atypical mycobacteria (author's transl)]. 1977410050
[leukocyte migration inhibition with soluble and particulate antigens (author's transl].studies were carried out with the leukocyte migration inhibition tests using soluble and particulate antigens (ppd, somatic antigens of t. cruzi, m. bovis (bcg) and leukocytes from patients sensitized to ppd and patients with chronic chagas' disease. the results obtained showed that the stimulatory capacity of particulate antigens are greater than that of soluble antigens.1977410077
sputum fixatives. 1977410208
pyrolysis-gas-liquid chromatography of mycobacteria. 1977410231
tryptophan uptake by mycobacterium tuberculosis h37rv--inhibition by isoniazid. 1977410415
epidemiologic significance of primary resistance in spain: refutation of the concept of transmission of resistant strains of mycobacterium tuberculosis. 1977410596
usefulness of transtracheal puncture and aspiration in the bacteriological diagnosis of pulmonary tuberculosis.transtracheal puncture enables two samples of bronchial secretions to be taken-the product of transtracheal aspiration and simultaneously expectorated sputum (obtained in 71% of the cases)-for the purpose of testing for mycobacterium tuberculosis in cases of suspected pulmonary tuberculosis. two groups of patients were studied: group i: 100 patients who were poor expectorators and who all underwent transtracheal puncture; group ii (control): 100 patients who expectorated well or who had been giv ...1977410734
occurrence with bacteriologically positive pulmonary tuberculosis.fever was unchanged by chemotherapy in ten patients with bacteriologically positive pulmonary tuberculosis. blood cultures were positive for gram-positive organisms in six patients and for gram-negative organisms in four patients. the same organism was present in sputa and blood in six patients and in urine and blood in two patients. leukocytosis was not found, and roentgenographic findings did not suggest superinfection. nine of the ten patients survived. blood cultures must be obtained in pati ...1977410959
comparison of the mode of immunopotentiating action of bcg and wax d. i. effect on the immune response to srbc.the immunopotentiating action of bcg and wax d was comparatively evaluated as the immune response to sheep red blood cells (srbc) in mice. the immunopotentiation of bcg varied with the interval between its priming and subsequent antigen injection. bcg increased delayed type hypersensitivity (dth) at early stage but enhanced antibody formation at later stage. dth reached its maximum about 5 weeks after bcg inoculation. in contrast, wax d increased antibody formation at early stage but increased d ...1977410972
[comparison of the therapeutic effects of secondary antituberculous drugs and evaluation of back-ground factors of the patients to the negative conversion of bacilli among the previously treated severe tuberculosis patients (author's transl)]. 1977410992
[phagocytic activity of the leukocytes in patients with a newly established diagnosis of silicotuberculosis]. 1977411124
[effect of acridine compounds on stopping the development of drug resistance in mycobacterium tuberculosis (an experimental study)]. 1977411125
[advantages of fluorescence microscopy compared to flotation in detecting mycobacterium tuberculosis]. 1977411126
[information content of fluorescence microscopy in determining the bacterial excretion in tuberculosis patients]. 1977411127
[prospects for improving the composition of the nutrient media for the bacteriological diagnosis of tuberculosis]. 1977411128
[decontamination of articles made of chemical fibers]. 1977411129
[isolation of mycobacterium tuberculosis cultures from soil]. 1977411130
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