| experimental chlamydiosis in wild and domestic lagomorphs. | chlamydia psittaci (strain m56, the agent of epizootic chlamydiosis of muskrats and hares) was highly lethal for the snowshoe hare (lepus americans) following intravenous inoculation, whereas the agent was much less virulent for cottontail (sylvilagus floridanus) and albino domestic rabbits (oryctolagus cuniculus). tissue titres of strain m56 were generally higher after 96 hr in the snowshoe hare than in tissues of the other lagomorphs. spleen, liver and bone marrow were apparently the chief sit ... | 1976 | 933312 |
| chlamydial antibodies in pigs in scotland. | | 1976 | 941375 |
| utilization of exogenous thymidine by chlamydia psittaci growing in the thymidine kinase-containing and thymidine kinase-deficient l cells. | the incorporation of [3h]thymidine into the deoxyribonucleic acid (dna) of chlamydia psittaci (strain 6bc) growing in thymidine kinase (adenosine 5'-triphosphate-thymidine 5'-phosphotransferase, ec 1.7.1.21)-containing l cells, l(tk+), and thymidine kinase-deficient l cells, lm(tk-), was examined by autoradiography. label was detected over c. psittaci inclusions in l(tk+) but not lm(tk-) cells. no evidence for a chlamydia-specific thymidine kinase activity in either l(tk+) or lm(tk-) cells was o ... | 1976 | 942715 |
| new department: teenage medicine. | | 1976 | 942756 |
| autoradiography of [3h]thymidine-labeled chlamydia psittaci 6bc in mononuclear phagocytes. | incorporation of tritiated [3h]thymidine by chlamydia psittaci 6bc was achieved by growing the parasites in chick embryo yolk sac explants which were exposed to exogenous labeled thymidine. these labeled, purified chlamydiae were next observed by autoradiography within mouse peritoneal macrophages. the number of silver grains remained constant in the cytoplasm of macrophages throughout the developmental cycle of the parasite. the proliferation of labeled chlamydiae in macrophages was confirmed b ... | 1976 | 943214 |
| alterations in the ultrastructure of chlamydia psittaci 6bc harvested from the allantoic fluid of chick embryos. | the allantoic fluid of chick embryos infected with chlamydia psittaci is routinely used as a source of material for the study of the chemical and biological properties of the chlamydiae. we have examined pellets recovered from this allantoic fluid by low- and high-speed centrifugation, as well as high-speed pellets which had been stored at -70 degrees c, and we find that all of the pleomorphic forms of the chlamydiae are present in these materials. the reticulate bodies and large intermediate bo ... | 1976 | 943217 |
| characterization of miniature pig kidney cells and their resistance to chlamydial infection. | a miniature pig kidney cell line has been established from porcine fetuses taken aseptically by hysterectomy and maintained for more than 50 passages in eagle's minimal essential medium containing 10% heat-inactivated newborn calf serum. cell transfers were performed each week. primary and serially passaged cells were found to be highly refractory to infection by chlamydia trachomatis strains tw-3, bour, and lgv 440l and chlamydia psittaci strains meningopneumonitis and 6bc and insusceptible to ... | 1976 | 944002 |
| [effect of dilysosomal macrophages on the development and outcome of pneumonia induced by the causative agent of enzootic abortion of sheep]. | repeated intranasal injections of increasing doses of bacterial lipopolysaccharide pyrogenal resulted in accumulation of numerous macrophages in the upper and middle parts of the mouse lungs; these macrophages were filled with leukocyte lysosomes. in these animals dilysosomal macrophages increased local resistance to the agent of enzootic ewe abortion and thus could change the lethal form of induced pneumonia into the nonlethal one. | 1976 | 945094 |
| the inactivation of chlamydia trachomatis by povidone-iodine. | | 1976 | 945260 |
| the gay bowel syndrome: clinico-pathologic correlation in 260 cases. | the clinical and pathological findings in a group of 260 homosexual men comprising 10% of a private proctologic practice are reviewed. a clinical pattern of anorectal and colon diseases encountered with unusual frequency in these homosexual patients is termed the gay bowel syndrome. the clinical diagnoses in decreasing order of frequency include condyloma acuminata, hemorrhoids, nonspecific proctitis, anal fistula, perirectal abscess, anal fissure, amebiasis, benign polyps, viral hepatitis, gono ... | 1976 | 946385 |
| laboratory-associated infections: summary and analysis of 3921 cases. | instances of overt laboratory-associated infection recorded in published reports and additional cases disclosed by questionnaires and personal communications have been tabulated. of a total of 3921 cases, 2465 occurred in the united states and 164 were fatal. only 64% of the cases were reported in the literature. analysis of the available information revealed that only 18% of the infections were due to known accidents; 42% were caused by bacteria; 27% by viruses; 15% by rickettsiae; 9% by fungi; ... | 1976 | 946794 |
| [chlamydial abortion in sheep and goats]. | | 1976 | 948836 |
| [cultivation of toxoplasma and chlamydia]. | | 1976 | 948844 |
| minocycline in the treatment of lymphogranuloma venereum. | in a study of 80 cases of lymphogranuloma venereum (lgv), minocycline hydrochloride (minocin) was found to be an effective drug in the treatment of all stages of lgv, including complicated ones. in late cases adjuvant treatment was used in addition to the antibiotic. healing time in uncomplicated cases was less than 10 days. in complicated cases, both early and late, healing took about 2 to 3 weeks. reactions to the drug were not significant. | 1976 | 956013 |
| ultrastructural study of the development of the agent of ewe's abortion. | | 1976 | 957470 |
| [a case of psittacosis treated with rifampicin (author's transl)]. | a 45-year-old male who had looked over pet-birds at a bird shop 11 days before, developed a high fever with chills. without any response to cephalexin, he was admitted to the hospital, with the chief complaints of high fever and sever headache on the 8th day of illness. the chest x-ray films taken then revealed a fun-shaped ground glass-like shadow extending over s10 of the right lung. after the oral administration of 450 mg rifampicin on the 9th day of illness, he became a febrile within one da ... | 1976 | 957515 |
| detection of dna polymerase activity in chlamydia psittaci. | dna polymerase activities of intact and disrupted suspensions of the mature infectious, extracellular elementary bodies of the meningopneumonitis strain of chlamydia psittaci were studied. intact elementary bodies failed to incorporate labeled thymidine triphosphate (ttp), but homogenates of the organisms did incorporate ttp into the acid insoluble fraction; the reaction continued at a linear rate for 60 min and the newly synthesized dna hybridized exclusively with dna derived from c. psittaci e ... | 1976 | 957524 |
| vaginal flora in asymptomatic women. | four groups of 25 asymptomatic women--pregnant, premenopausal and taking oral contraceptives, premenopausal and not taking oral contraceptives, and postmenopausal--were studied for the presence in vaginal specimens of aerobic bacteria, anaerobic bacteria, fungi, mycoplasma, chlamydia, herpes simplex virus, mycobacteria, and trichomonas. no significant differences in microbial flora were found among the groups. | 1976 | 957791 |
| [pathologicoanatomic and histomorphological changes in the fetus in chlamydial abortion in swine]. | | 1976 | 960539 |
| animal model studies of genital chlamydial infections. immunity to re-infection with guinea-pig inclusion conjunctivitis agent in the urethra and eye of male guinea-pigs. | a previous report demonstrated that male guinea-pigs could be infected in the urethra with guinea-pig inclusion conjunctivitis (gpic) agent and that the infection was transmitted during mating from infected males to females. in the experiments reported here, inoculation of male guinea-pigs in the urethra with gpic organisms resulted in infection which subsided spontaneously in about 2 weeks. males were demonstrated to be completely resistant to urethral challenge with 10(3)id50 when tested 6 wee ... | 1976 | 963491 |
| differences in physicochemical and antigenic properties of chlamydial strains. | antigenic analysis of chlamydia psittaci, c. trachomatis, and lymphogranuloma venereum (lgv) revealed basic physicochemical differences among the three chlamydial strains. these were manifested in structural, isoelectric points, absorption spectra, and in the characteristics of the chromophobe-containing proteins. the effective period of sonication for c. psittaci and c. trachomatis is around 60 min during which the linkages most susceptible to external sonication forces were broken, releasing a ... | 1976 | 963615 |
| requirements for ingestion of chlamydia psittaci by mouse fibroblasts (l cells). | ingestion of 14c-amino acid-labeled chlamydia psittaci (6bc) by mouse fibroblasts (l cells) was inhibited when the host cells were incubated for 30 min at 37 degrees c in earle salts containing 10 mug of crystalline trypsin per ml. tryptic digestion also inhibited the ingestion of 1-mum polystrene latex beads. trypsin-treated l cells almost completely recovered their ability to ingest chlamydiae after 4 h at 37 degrees c in medium 199 with 5% fetal calf serum. cycloheximide (10 mug/ml) blocked t ... | 1976 | 965090 |
| [comparative study of the pathogenicity of chlamydia for white mice of different ages]. | | 1976 | 967061 |
| [role of bovine respiratory syncytial virus in the aetiology of viruspneumonia in calves and yearlings ("pinkengriep") (author's transl)]. | the clinical picture of "pinkengriep", an enzootic form of bronchopneumonia in young cattle, is described. in addition to cough, conjunctivitis and a soporous state, accelerated respiration initially is an outstanding clinical symptom. in some cases, symptoms of fog fever appear during the second stage of the disease. in the autumn of 1973 and that of 1974, a total number of 292 animals with "pinkengriep" were serologically examined for known respiratory virus infections and chlamydia. complemen ... | 1976 | 968892 |
| antibodies to two immunotypes of chlamydia trachomatis in individuals with trachoma. | in tunisia (north africa), trachoma remains a common eye disease. most cases are caused by immunotype a of chlamydia trachomatis. in a small proportion of cases (less than 10%), type-specific antibodies to both immunotype a and immunotype b exist in the serum of patients. these types do not crossreact, and occasionally sequential acquisition of antibodies has been demonstrated. thus, individuals in one endemic area of trachoma may be infected with two immunotypes of c. trachomatis. the epidemiol ... | 1976 | 971956 |
| comparison of urethral swabs, urine, and urinary sediment for the isolation of chlamydia. | in 70 male patients with urethritis, chlamydia was recovered from 18 urethral swabs (26%), 5 urinary sediments (7%), and 3 urine specimens (4%). all chlamydia isolates were recovered from urethral swabs. | 1976 | 972182 |
| [role of chlamydia in chronic renal and urogenital diseases in man]. | serological examinations by the cft with the group-specific ornithosis antigen were carried out with 1910 sera from patients with chronic diseases of the kidneys, urinary tracts and male sexual organs, as well as with 556 control sera from patients with cardio-vascular and other diseases for elucidation of the role of chlamydia (olt group) in the infectious pathology of the kidneys and urinary tracts of man. no complement-fixing antibody was detected with the group-specific ornithosis antigen in ... | 1976 | 983001 |
| occurrence of antibodies to group specific chlamydia antigen in cattle and reindeer sera in finnish lapland. | | 1976 | 983896 |
| effect of gentamicin on growth of viral, chlamydial, and rickettsial agents in mice and embryonated eggs. | gentamicin, at concentrations up to 500 mug/ml, showed no effect on the replication, yield, or infectivity of seven viruses or on the agents of psittacosis and meningopneumonitis when grown in mice or embryonated eggs. at the 500 mug/ml level, lymphogranuloma venereum cultures had a slight reduction in infectivity. rickettsia akari demonstrated susceptibility at the 5 mug/ml level, whereas r. rickettsii, r. mooseri, and r. canada grown in embryonated eggs were susceptible in varying degrees to g ... | 1976 | 984775 |
| immediate toxicity of high multiplicities of chlamydia psittaci for mouse fibroblasts (l cells). | one hour after suspensions of mouse fibroblasts (l cells) were exposed to 500 to 1,000 l-cell 50% infectious doses of chlamydia psittaci (6bc), the l cells failed to attach to and spread out on solid substrates, phagocytosed polystyrene latex spheres at reduced rates, incorporated less [14c]isoleucine into protein, and had smaller soluble pools of nucleoside triphosphates. the infected l cells began to die at 8 h and were all dead by 20 h. lower multiplicities of infection took correspondingly l ... | 1976 | 985806 |
| noninfectious canine arthritis: rheumatoid arthritis. | chronic unremitting, generally symmetric, erosive polyarthritis was studied in 8 dogs. the disease had clinical, serologic, radiographic, and pathologic changes similar to those of rheumatoid arthritis of man. the condition occurred mainly in smaller breeds of dogs, with time of onset from 8 months to 8 years of age, characteristic radiographic changes were seen in the joints several weeks to several months after the appearance of the initial lameness. synovial fluid contained an increased numbe ... | 1976 | 986380 |
| infectivity titration of guinea-pig inclusion conjunctivitis agent in irradiated mccoy cells. | estimation of the infectivity of the agent of guinea-pig inclusion conjunctivitis for irradiated mccoy cells, assayed as inclusion-forming units, was influenced by the age of cells after irradiation, the maturation time of the inclusions, the centrifugal force and the centrifugation temperature. agent passaged through irradiated mccoy cells or guinea-pig conjunctivae showed a greater capacity to infect irradiated mccoy cells without centrifuging than agent grown in a chick embryo. the nature of ... | 1976 | 986419 |
| phagocytic and chlamydiae-inhibiting activities of stimulated and nonstimulated periotneal mouse macrophages. | phagocytic and chamydiacidal properties of nonstimulated and stimulated mouse mononuclear cells for two chlamydia psittaci 6bc strains were investigated. it was determined that macrophages kept in monolayer culture (i.e. stimulated phagocytes) developed much more efficient chlamydiacidal ability than did cells kept in suspension directly after harvest (i.e. nonstimulated phagocytes). a thousandfold decrease of chlamydial infectivity was observed 60 min after induction of phagocytosis in stimulat ... | 1976 | 986871 |
| observations on the involvement of wildlife in an epornitic of chlamydiosis in domestic turkeys. | in an investigation of potential wildlife reservoirs of chlamydia psittaci at the site of an acute, highly fatal epornitic of chlamydiosis in domestic turkeys in texas, various species of wild birds and rodents were captured and tested for chlamydial serum antibodies and chlamydiae in their tissues. thirteen (65%) of 20 blackbirds (agelaius sp), 4 (44%) of 9 killdeer (oxyechus vociferus), 3 (27%) of 11 sparrows (passer sp) and 1 of 4 mourning doves (zenaidura macroura) were seropositive, but chl ... | 1976 | 988009 |
| letter: lymphogranuloma venereum. | | 1976 | 988883 |
| therapy for venereal diseases. | | 1976 | 989606 |
| experimental study of the antitrachoma action of berberine. | | 1976 | 992845 |
| how does the external eye resist infection. | | 1976 | 992961 |
| [micromethod of semiquantitative fixation of the useable complement in serology of ovine chlamydia infections. technic with 50 percent of hemolysis]. | | 1976 | 993217 |
| some physical properties of a sheep pneumonia strain of chlamydia psittaci. | | 1976 | 997192 |
| studies on the response of ewes to live chlamydiae adapted to chicken embryos or tissue culture. | ewes infected before gestation with chicken embryo or tissue culture adapted chlamydial strain b-577 were challenge inoculated with the homologous strain at four to 18 weeks of gestation. the ewes responsed with group specific complement fixing antibody titers of 1:8 to 1:256 by the second week after initial infection. a secondary antibody response in the surviving challenge inoculated ewes occurred at the time of lambing and reached titers of 1:32 to 1:256 by the second week after parturition. ... | 1976 | 1000377 |
| investigations on some antigenic relationships between different human, mammalian and avian chlamydia strains. | serological investigations were performed in order to establish the antigenic relationships between three chlamydia strains: t44(subgroup a), t13 and q18 (subgroup b). by using monospecific mouse immune sera a certain degree of antigenical relationships was made evident and the strains could be typed by microagglutination and microimmlnofluorescence reactions. similar results were obtained by seroneutralization with hyperimmune sera prepared in the rooster. complement fixation proved to be a gro ... | 1976 | 1006984 |
| chlamydial pneumonia in a buffalo calf. | | 1976 | 1007707 |
| isolation of chlamydia trachomatis from women attending a clinic for sexually transmitted diseases. | attempts were made to isolate chlamydia trachomatis from the cervix of 300 women attending a clinic for sexually transmitted diseases in leeds. the women were divided into four groups; (1) 130 were consorts of men suffering from non-specific urethritis; (2) 66 were suffering from gonorrhoea, or were consorts of men suffering from this disease; (3) 56 were suffering from other sexually transmitted diseases; (4) 48 had no evidence of std. the overall isolation rate of chlamydia trachomatis was 20% ... | 1976 | 1009420 |
| intrarectal infection of guinea pigs with the agent of guinea pig inclusion conjunctivitis. | | 1976 | 1013148 |
| ultrastructural changes in host cellular organelles in the course of the chlamydial developmental cycle. | different stages in the chlamydial developmental cycle were correlated with cytopathic changes in host cellular organelles by ultrastructural analysis of infected cultured cells and cells of the intestinal mucosa of newborn calves. four distinct morphologic forms of chlamydial development can be distinguished: elementary bodies, dispersing forms, reticulate bodies and condensing forms which proceed to form elementary bodies. from the stage of elementary body uptake through formation and multipli ... | 1976 | 1015025 |
| the tric agent in the female genital tract; a cytologic and virologic study in a trachomatous hyperendemic area. | | 1976 | 1032928 |
| [abortive infection of mice inoculated intraperitoneally with chlamydia ovis]. | a mouse adaptated strain of chlamydia ovis, when inoculated in the peritoneal cavity, caused the death of both pregnant and non pregnant mice. in addition, mice inoculated late in pregnancy (12 to 16 days after breeding) aborted 4 to 6 days after inoculation. chlamydia was recovered from foetuses and from the organs of the mice (liver, spleen, lungs). the severity of the disease was related to the inoculum concentration, so it was possible to induce late abortions with a rapid recovery of the fe ... | 1976 | 1035841 |
| nongonococcal urethritis. | nongonococcal urethritis may now account for most cases of symptomatic urethritis seen at vd clinics in the united states. well-controlled etiologic studies in nongonococcal urethritis have implicated chlamydia in over 40% of cases but the etiology of chlamydia-negative cases remains uncertain. tetracycline provides effective antimicrobial therapy, but tests for cure are often inadequate, and distinguishing relapse and reinfection is difficult. for tetracycline-allergic patients, erythromycin sh ... | 1976 | 1037101 |
| chlamydial ophthalmia neonatorum. | a case of chlamydial ophthalmia neonatorum is presented. the importance of early diagnosis and treatment is discussed. | 1976 | 1063920 |
| isolation of chlamydia in acute salpingitis. | in 22 patients with acute salpingitis, verified by laparoscopy, samples for attempted isolation of bacteria, mycoplasma and chlamydia were drawn from aspirates and cervical smears. cf-antibodies to chlamydia were measured to acute and convalescent phase sera. anaerobic bacteria were isolated from tubal secretions in two patients and mycoplasmas in one patient. in two patients chlamydia were recovered from the fallopian tube. the serological investigation indicated chlamydia infection in 6 patien ... | 1976 | 1070151 |
| antigenic analysis of chlamydiae by two-dimensional immunoelectrophoresis. i. antigenic heterogeneity between c. trachomatis and c. psittaci. | tw0-dimensional immunoelectrophoresis was used for the antigenic analysis of chlamydia. antigens of chlamydiae were found to be successfully solubilized with the nonionic detergent triton x-100. nineteen and 16 distinct components were observed for chlamydia trachomatis strain l2/434/bu and c. psittaci strain meningopneumonitis/cal-10, respectively. the triton-solubilized antigens of chlamydiae differ strikingly between species since only one strong reciprocal cross-reacting antigen was observed ... | 1975 | 1080772 |
| chlamydiae as agents of sexually transmitted diseases. | chlamydiae are being increasingly recognized as an important cause of human disease. the known geographical distribution of lymphogranuloma venereum and the role of chlamydiae as agents of sexually transmitted diseases are reviewed. the presence of chlamydiae in the urethra and the cervix, and their etiological relationship to genital infections, first recognized in connexion with ocular infections, have been proved in a number of studies in selected populations in a few countries. chlamydiae ap ... | 1976 | 1088107 |
| bacteriological and viral serological observations in egyptian rural school-children with clinical signs of eye infection. | | 1976 | 1088550 |
| lysosomes and the "toxicity" of rickettsias. vi. in vivo response of mouse peritoneal phagocytes to l-cell-grown chlamydia psittaci 6bc strain. | the l-cell-grown 6bc strain of c. psittaci inoculated intraperitoneally in mice induced an injurious effect on mononuclear phagocytes and their lysosomes; the influx of polymorphonuclear phagocytes (pmn's) increased markedly and the pmn's showed karyorrhexis and lysis. cytochemical methods failed to detect chlamydial forms in peritoneal fluids from day 1 and up to 6 days after inoculation of mice. chlamydial infectivity was not detected in either the cell-bound or the cell-free fractions of peri ... | 1975 | 1090349 |
| neutralization of chlamydia trachomatis in cell culture. | neutralization of chlamydia trachomatis was assayed by the decrease in inclusion-forming units in baby hamster kidney cells grown in culture. five percent fresh guinea pig sera increased neutralization titers of rabbit antisera 100- to 1,000-fold but had no effect when normal rabbit sera were tested. neutralization of a type a or b trachoma isolate was strain specific. neutralization by human eye secretions and sera also was demonstrated when guinea pig sera were included in the test. all of the ... | 1975 | 1091549 |
| serotyping of chlamydia: isolates of bovine origin. | chlamydial isolates of bovine origin were serotyped by a plaque reduction method. of the two major serotypes observed, type 1 included isolates from bovine abortion and enteric infections, whereas type 2 isolates were associated with polyarthritis or encephalomyelitis. these two serotypes were identical to those with a similar disease distribution previously observed in isolates of ovine origin. the two groups did not cross-react and they were serologically unrelated to chlamydiae of avian origi ... | 1975 | 1091564 |
| [experimental bedsonia infection of calves]. | | 1975 | 1092055 |
| acute undifferentiated neonatal diarrhea in beef calves. i. occurence and distribution of infectious agents. | beef calves in a 48-cow herd were studied during one calving season from birth to ten days of age to determine the presence or absence of potentially enteropathogenic bacteria, viruses, and/or chlamydia in both normal and diarrheic calves. calves were born and raised outside in large pens unless the ambient temperature was below minus 10 degrees f when calving was done inside. fecal swabs, fecal aliquots, and nasal swabs were taken from each calf at 32, 128 plus or minus 3, and 248 plus or minus ... | 1975 | 1092438 |
| editorial: chlamydia, trachoma, genital infection, and psittacosis. | | 1975 | 1093566 |
| light and electron microscopic study of chlamydia trachomatis infection of the uterine cervix. | cervical biopsy specimens from two patients with infections caused by chlamydia trachomatis (tric agent) were studied by means of light and electron microscopy. intraepithelial vesicles containing c. trachomatis were present in the cervical mucosa. these intramucosal vesicles were readily recognized in paraffin sections by means of light microscopy. the developmental stages of c. trachomatis, which have previously been seen in tissue cell culture, chicken embryo, and conjunctival infections, wer ... | 1975 | 1094072 |
| non-specific urethritis and the tetracyclines. | the possible aetiological factors in non-gonococcal and non-specific urethritis are reviewed. the response of nsu to various courses of different tetracycline drugs is assessed. prolonged courses of treatment did not give better results than shorter courses. when reviewing the infective aetiology of non-gonococcal urethritis, it was noted that more than one organism (or potential pathogen) would be present in many cases. it is therefore surmised that there may be at times a mixed aetiology and a ... | 1975 | 1095144 |
| competition between chlamydia psittaci and l cells for host isoleucine pools: a limiting factor in chlamydial multiplication. | l cells (mouse fibroblasts) supported the multiplication of the obligately intracellular parasitic bacterium chlamydia psittaci (strain 6bc) when incubated in fresh growth medium (medium 199 + 5% fetal calf serum). when incubated in the medium supernatant from a 24-h-old culture of uninfected l cells (24-h used medium), uninfected cells did not divide and infected cells did not provide an adequate environment for the multiplication of c. psittaci, which persisted in a noninfectious latent state ... | 1975 | 1095493 |
| topical tetracycline and rifampicin therapy of endemic trachoma in tunisia. | a controlled chemotherapy trial of trachoma was carried out in a tunisian oasis among schoolchildren with active disease. we compared 1% tetracycline ointment (79 patients) or 1% rifampicin ointment (76 patients) with 5% boric acid ointment (79 patients). medications were administered twice daily, six days a week, for ten weeks. slit-lamp examinations by three ophthalmologists were made independently before treatment as well as five, 19, and 39 weeks after treatment. bacteriologic cultures were ... | 1975 | 1096630 |
| immunofluorescence of peritoneal phagocytes after infection of mice with l-cell-attenuated chlamydia psittaci 6bc. | large amounts of particulate antigen of chlamydia psittaci 6bc attenuated by growth in l cells were phagocytized by peritoneal mononuclear phagocytes during the 1st h after intraperitoneal inoculation. the phagocytes subsequently destroyed the immunofluorescent (if) properties of the chlamydial antigens. it is suggested that the early damage of phagocytes by lysosomal enzymes activation induced by chlamydiae contributed to the relatively early disappearance of if antigens from the peritoneal flu ... | 1975 | 1097065 |
| new knowledge of chlamydiae and the diseases they cause. | the trachoma and lgv organisms, the human pathogens of the species c. trachomatis, cause oculogenital infections and disease syndromes of the eye and genital tract. the incidence of the most prominent disease, endemic trachoma with eye-to-eye transmission, is decreasing all over the world. at the same time there is increasing recognition of high-frequency venereal infections with trachoma organisms and of the genital disease and occasional ocular disease that they cause. laboratory techniques fo ... | 1975 | 1097546 |
| simplified microimmunofluorescence test with trachoma-lymphogranuloma venereum (chlamydia trachomatis) antigens for use as a screening test for antibody. | a simplified microimmunofluorescence test with trachoma-lymphogranuloma venereum (chlamydia trachomatis) antigens has been devised as a screening test for antibody in human sera. the test differs from our standard procedure by amalgamating 15 different immunotypes into nine antigen pools, by using only three serum dilutions, and by dropping use of duplicate slides. the screening test could be performed on at least six times as many sera as the standard test for a given unit of effort. it was sho ... | 1975 | 1100657 |
| fluorescent antibody studies in chlamydial infections. | irradiated mccoy cells infected with genital strains of chlamydia trachomatis were grown in wells on slides coated with polytetrafluoroethylene. the inclusions produced in this system formed the antigen in an indirect immunofluorescence test, which detected group-specific chlamydial antibodies in sera from patients attending veneral disease clinics. chlamydial antibodies were found more frequently and in higher titer in sera from women attending veneral disease clinics then in sera from a less p ... | 1975 | 1100663 |
| microbial flora of the lower genital tract during pregnancy: relationship to morbidity. | nineteen genera and groups of micro-organisms were isolated from the lower genital tract of 280 women at their first antenatal visit. chlamydia, viruses, and t-strain mycoplasmas were not sought, and only routine methods of anaerobic culture were used. growth was recorded as scanty, moderate or heavy. the population studied was grouped according to age, parity, gestational stage at booking, presence and degree of severity of lower genital tract morbidity, past history of vulvovaginitis, and susp ... | 1975 | 1100681 |
| identification of the elementary bodies of chlamydia trachomatis in the electron microscope by an indirect immunoferritin technique. | an indirect immunoferritin (iif) technique is described for recognizing the elementary bodies (eb) of chlamydia trachomatis in unsectioned preparations. both the eb of a genital strain of c. trachomatis grown in irradiated mccoy cells and eb in clinical specimens obtained from patients attending a venereal disease clinic were identified by the iif test in the electron microscope. cell culture-grown eb were detected by ferritin staining for up to 4 weeks after the organisms had lost their infecti ... | 1975 | 1102559 |
| the occurrence and pathology of chlamydiosis in domestic and laboratory animals: a review. | the literature on the various disease syndromes caused by chlamydia in domestic and laboratory animals is summarized. a review of the pathological lesions which characterize these diseases is presented and the pathogenesis of chlamydiosis is briefly discussed. some aspects of unpublished findings on the occurrence of intestinal, kidney and genital lesions in natural and experimental cases of chlamydiosis in cattle and sheep, abortions and conjunctivitis in horses in south africa are recorded. | 1975 | 1105281 |
| lymphogranuloma venereum. | | 1976 | 1107239 |
| isolation of chlamydia in irradiated and non-irradiated mccoy cells. | specimens from eye and genital tract were cultured in parallel in irradiated and non-irradiated mccoy cells and the frequency of isolation of chlamydia using these culture methods was compared. there was a significant difference between the frequencies of isolation; irradiated mccoy cells produced a greater number of positive results. | 1975 | 1107357 |
| [study of the specificity of various classes of immunoglobulins (igm and igg) v techenie ornitoznoĭ infektsii]. | studies of the specificity of immunoglobulins of different classes in the course of both experimental and natural orinthosis infection showed igg antibody to possess a wide spectrum of activity: group-, species- and strain-specific, but specificity to group antigenic components was predominant. igm antibodies were species-specific, however, population of gammam-immunoglobulins of animal sera in approximately 7 and 14 days after infection antibody suggested a method for the study of the antigenic ... | 1975 | 1108451 |
| an epornitic of fatal chlamydiosis (ornithosis) in south carolina turkeys. | an unusual epornitic of fatal chlamydiosis occurred in a flock of 10,283 domestic turkeys in south carolina. total mortality over a 2-week period was 483 birds (4.7% of the flock). the principal gross lesion was severe pericarditis, but there was little or no airsacculitis, an observation at variance with many previous reports of chlamydiosis. furthermore, an unusually heavy infestation of the turkeys with sanguivorous black flies (simulium slossonae and s congareenarum) was observed at the time ... | 1975 | 1112744 |
| recurrent t.r.i.c. kerato-conjunctivitis: treatment with tetracycline. | trachoma inclusion conjunctivitis agent infections have a spectrum of clinical presentations which in their more chronic forms are often difficult to recognize. patients with epithelial erosions of the upper cornea, episodic e.k.c. type subepithelial infiltrates, pannus or micropannus, and with or without lid scarring, merit conjunctival scrapings as an aid to diagnosis. since the agents which produce these infections have a genital reservoir, as the prevalence of venereal diseases increases, th ... | 1975 | 1122419 |
| [letter: virus of the psittacosis group in reiter's disease]. | | 1975 | 1126851 |
| [demonstration of group-specific precipitation antibodies in chlamydia infections of poultry]. | | 1975 | 1131157 |
| letter: sticky eye in the newborn. | | 1975 | 1131530 |
| [sexual life and fertility of men with positive antibodies against bedsoniae]. | | 1975 | 1131971 |
| vaginitis. | | 1975 | 1144275 |
| [role of chlamydia in the etiology of reiter's disease]. | | 1975 | 1144950 |
| protein profiles of dense-centered forms of five chlamydial strains of animal origin. | purified dense-centered form of 1 bovine strain (lw613) and 3 ovine strains (b577, 034-eye, and 047-eye) of chlamydia psittaci and 1 murine strain of chlamydia trachomatis (mopn) were dissociated in the presence of sodium dodecyl sulfate (sds) and 2-mercaptoethanol. the number of polypeptides detected in the 5 strains varied between 17 and 20, with a molecular weight range of 29,000 to 120,000. two polypeptides predominated and comprised approximately a third of the total protein in each of the ... | 1975 | 1147351 |
| electron microscopy of the in vivo internalization of virulent chlamydia psittaci 6bc strain. | the internalization of virulent chlamydia psittaci 6bc particles by wandering mononuclear phagocytes in the peritoneal cavity of intraperitoneally inoculated mice occurred asynchronously, i.e., fragile reticulate bodies (rb) appeared to be more readily phagocytized than the rigid elementary bodies (eb). early damage of mononuclear phagocytes occurred after internalization of chlamydiae. this was followed by a decreased uptake of particles, and may explain the relatively long persistence (up to ... | 1975 | 1148946 |
| acute epididymitis attributable to chlamydial infection -- preliminary report. | two cases of acute epididymitis are described in which there was found to be a significant rise in the titre of antibodies to the chlamydial group of organisms. it is suggested that chlamydial infection is a cause of acute epididymitis. | 1975 | 1152743 |
| comparison of antigenic structure and pathogenicity of bovine intestinal chlamydia isolate with an agent of epizootic bovine abortion. | a bovine fecal chlamydia, isolated from a clinically normal cow, had pathogenic capabilities and antigenic structure similar to those of a chlamydial agent of epizootic bovine abortion (eba). intravenous inoculation of the fecal chlamydia into a pregnant heifer caused abortion and lesions in the fetus indistinguishable from those of experimentally induced eba. in serotests with species-specific complement fixation antigens, the intestinal agent was similar to the eba agent. | 1975 | 1155834 |
| minocycline in the treatment of nongonococcal urethritis: its effect on chlamydia trachomatis. | the effect of minocycline on nongonococcal urethritis (ngu) was investigated, with particular reference to its action against chlamydia trachomatis. preliminary laboratory studies showed that the drug was active against a laboratory chlamydial strain (lb4f) in vitro. a group of 133 men with first attacks of ngu was then treated with minocycline, 100 mg twice daily for 3 weeks. isolates of c trachomatis were obtained from 33 of these men before treatment; all of them gave negative results on cell ... | 1975 | 1158770 |
| proceedings: psittacosis. | | 1975 | 1165305 |
| [use of agar gel precipitation test for the diagnosis of chlamydia infections in the cattle and sheep]. | | 1975 | 1167282 |
| utilization of l-cell nucleoside triphosphates by chlamydia psittaci for ribonucleic acid synthesis. | long-term, 32-p-labeled l cells were infected with the obligately intracellular parasite chlamydia psittaci (strain 6 bc). at 20 h postinfection, [3-h]uridine was added, and the infected cells were sampled at intervals for incorporation of the labels into the uridine triphosphate (utp) and cytidine triphosphate (ctp) pools of the host l cell and the uridine monophosphate (ump) and cytidine monophosphate (cmp) in 16s ribosomal ribonucleic acid (rna) of the parasite. the specific activity of the n ... | 1975 | 1168632 |
| report of a workshop: disease accentuation after immunization with inactivated microbial vaccines. | | 1975 | 1169271 |
| [psittaciadae, bedsonia organisms, fungi and yeasts (author's transl)]. | | 1975 | 1171536 |
| ultrastructural cytochemical evidence for the activation of lysosomes in the cytocidal effect of chlamydia psittaci. | the cytopathic effect of the polyarthritis strain of chlamydia psittaci was studied in cultured bovine fetal spleen cells and found to be mediated by the release of lysosomal enzymes into the host cytoplasm during the late stages of chlamydial development. ultrastructural cytochemical analysis and cell fractionation studies of infected cells revealed a close relationship between the stage of chlamydial development, fine structural features of the host, and localization of lysosomal enzyme activi ... | 1975 | 1172486 |
| chlamydial pharyngitis? | | 1975 | 1174110 |
| [demonstration of pathogens in lymphogranuloma inguinale. an electron microscopy study]. | a case of lymphogranulomatosis inguinalis is reported, in which the definite diagnosis was made by the electronmicroscopical demonstration of chlamydia lymphogranulomatosis in the lymphnode. the value of this diagnostical method is discussed in regard to verifying the diagnosis and in comparison with other methods. the lifecycle of the chlamydia lymphogranulomatosis could be demonstrated electronmicroscopically. its exceptional position in microbiological classification is discussed. | 1975 | 1176287 |
| human psittacosis associated with commercial processing of turkeys. | between may 1 and aug 1, 1974, 114 of approximately 1,000 employees in 7 turkey processing plants in texas (5), missouri (1), and nebraska (1) had an illness compatible with psittacosis. the illness was characterized by fever, severe headache, and pneumonia. treatment with tetracycline was effective in most cases. psittacosis was confirmed in 41 (36%) of the cases by a fourfold change in complement-fixation titer to the chlamydia group antigen. investigations implicated several turkey flocks fro ... | 1975 | 1184442 |
| pneumonitis following inclusion blennorrhea. | a pregnant woman and her husband had proved chlamydial genital tract infections. she gave birth to a male infant who developed inclusion blennorrhea (inclusion conjunctivitis of the newborn infant). while on topical chemotherapy for his eye disease, the infant developed pneumonitis. chlamydiae were recovered from his sputum at a time when conjunctival specimens were sterile. this finding raises the possibility that the agent of inclusion conjunctivitis may cause systemic infections in neonates e ... | 1975 | 1185349 |
| letter: nongonococcal urethritis. | | 1975 | 1186811 |
| [comparative studies on the execution of the complement fixation test. 1. studies on the antigen dilution using an ornithosisantigen]. | | 1975 | 1189568 |
| [comparative studies on the execution of the complement fixation test. 2. comparison of serum titers, illustrated with ornithosis complement fixation tests]. | | 1975 | 1189569 |