| single-unit activity in the auditory cortex of monkeys selectively attending left vs. right ear stimuli. | single-unit responses were recorded from the auditory cortex of rhesus monkeys that were performing an auditory selective attention task. acoustic stimuli were presented randomly to either the left or right ear through headphones. in a given block of trials one ear was selected as the ear to be attended, and was indicated by lighting either a left or right response key. the animal's task was to press the lighted key whenever stimuli were presented to the attended ear, but to make no response to ... | 1978 | 103597 |
| prolonged alterations of muscle activity induced in locomoting premammillary cats by microstimulation of the inferior olive. | | 1978 | 103600 |
| restricted posterior parietal lesions in the rhesus monkey and performance on visuospatial tasks. | monkeys with lesions restricted to the inferior parietal lobule or the banks and depths of the superior temporal sulcus were tested on a route-following task. these areas are considered on neuroanatomical grounds to be homologous to parts of the human posterior parietal cortex, where lesions produce profound spatial disorientation. the operated monkeys were impaired on the route task, thus confirming at the behavioural level the anatomical predictions of comparability between parietal cortex in ... | 1979 | 103604 |
| organization of the sympathetic innervation in liver tissue from monkey and man. | the sympathetic innervation of the liver of monkey and man has been investigated in a combined fluorescence histochemical, chemical and electron microscopical study. by means of the falck-hillarp fluorescence method a dense network of monoamine-containing nerve fibers was visualized in liver tissue of monkey and man. the nerve fibers ran in close contact to both hepatocytes and blood vessels. chemical quantitations showed high concentrations of noradrenaline in both human and monkey liver. micro ... | 1978 | 103622 |
| oligosaccharides and polysaccharides specifically utilizable by bifidobacteria. | | 1978 | 103638 |
| [epileptogenic action of intra-amygdaloid injection of kainic acid]. | intra-amygdaloid unilateral application of low doses of kainic acid rapidly elicits, in both chronic and acute conditions, secondarily generalized convulsive seizures which often culminate in fatal true status epilepticus unless appropriate anti-epileptic drugs are provided. spontaneous recurrent seizures are observed for several hours starting approximately 10 min. after the application of kainic acid. in addition to the primary degeneration in the amygdaloid complex, a secondary cell loss is s ... | 1978 | 103652 |
| homovanillic acid in human csf: comparison of fluorimetry and gas chromatography-mass spectrometry. | | 1978 | 103678 |
| neostigmine activated epileptiform discharge in the amygdala: electrographic-behavioral correlations. | this investigation was carried out to test the hypothesis that amygdaloid epileptiform activity is due to cholinergic hyperactivity. it was designed to study the underlying physiopathology of, and to act as an experimental model for, psychomotor epilepsy. neostigmine was injected intracerebrally into the amygdala of the cebus monkey with chronically implanted "chemitrodes" fitted with eeg recording electrodes. the injections were made in the basal amygdaloid nucleus which normally shows very hig ... | 1978 | 103709 |
| toxoplasma gondii: penetration into differentiating friend erythroleukemia cells. | | 1978 | 103745 |
| a new sequence-specific endonuclease from anabaena cylindrica. | | 1978 | 103749 |
| molecular heterogeneity of dna polymerase alpha from p815 mouse mastocytoma cells. | | 1978 | 103750 |
| the use of immunoelectro-osmophoresis as a possible aid in the diagnosis of swine fever. | | 1978 | 104511 |
| [comparison of two methods of antibiotic sensitivity tests: gel diffusion and automatic method using abac apparatus. i. variation and dispersion of the two methods (author's transl)]. | the authors studied comparatively the sensitivity of 3 bacterial strains (p. aeruginosa and two e. coli) with regard to antibiotics using an automatic method (abac) compared with a gel diffusion technic with impregnated disks. each strain was tested by both methods 50 to 55 times. the diffusion method was easily reproducible with an average standard deviation of 2.23 mm. its results were in agreement compared with the average diameter of measurements in 93.3% of cases. the automatic method gave ... | 1978 | 104642 |
| human hydatidosis: evaluation of three serodiagnostic methods, the principal subclass of specific immunoglobulin and the detection of circulating immune complexes. | three serological methods were examined for the diagnosis of hydatid disease: indirect haemagglutination, immuno-electrodiffusion and radioimmunoassay. the sensitivity of the three methods was similar. the principal subclass of specific anti-hydatid immunoglobulin was igg and high levels of specific anti-ige were found in two out of the five patients studied. the hypothesis that false negative reactions seen in patients with clinically confirmed hydatidosis may be due to the presence of circulat ... | 1978 | 104670 |
| high affinity uptake sites for taurine in the retina. | | 1978 | 104877 |
| effects of immunization with the beta-subunit of ovine luteinizing hormone on corpus luteum function in the rhesus monkey. | rhesus monkeys immunized with the beta-subunit of ovine luteinizing hormone (olhbeta) developed circulating antibodies which cross-reacted strongly with rhesus monkey chorionic gonadotropin. normal ovulatory cycles continued, but the fertility of immunized monkeys as compared with that of controls was significantly reduced. thus, the rhesus monkey represented a useful animal model for the study of certain aspects of an "antifertility vaccine." we investigated the effects of circulating antibodie ... | 1979 | 104890 |
| [study of the initial stages of microorganism growth and development for assessing the bactericidal action of chemical substances]. | | 1979 | 104902 |
| effect of auranofin, a new antiarthritic agent, on immune complex-induced release of lysosomal enzymes from human leukocytes. | auranofin, an oral chrysotherapeutic agent effective in the treatment of rheumatoid arthritis (ra), was found to be a potent, noncytotoxic inhibitor of igg-rf immune complex-induced lysosomal enzyme release (ler) from human leukocytes. at a concentration of 1 microg au/ml (5 microm), auranofin produced a marked reduction in beta-glucuronidase (100%), acid phosphatase (88%), and lysozyme (72%) release. in contrast, gold sodium thiosulfate (gst, an injectable gold compound) had no inhibitory activ ... | 1977 | 104928 |
| transcription and translation in a pleiotropic streptomycin-resistant mutant of escherichia coli. | the role of the ribosomal protein s12 (streptomycin protein) in ribosome function and in other metabolic processes in the cell has been investigated. a spontaneous streptomycin-resistant strain of escherichia coli (sm3) carrying a mutation in the rpsl gene is deficient in its ability to induce the synthesis of the enzyme bets-galactosidase. it was demonstrated that the reduced rate of enzyme synthesis results from deficiencies in both the transcription of the lactose operon and translation of th ... | 1979 | 104958 |
| separation and characterization of highly purified forms of liver microsomal cytochrome p-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. | | 1979 | 105007 |
| turnover of human and monkey plasma kininogens in rhesus monkeys. | the normal metabolic turnover of plasma kininogens was studied by measuring the disappearance of intravenously administered radiolabeled human and monkey plasma kininogens from the circulation of healthy adult rhesus monkeys. curves obtained by plotting log radioactivity against time could be expressed as double exponential equations, with the first term representing diffusion, and the second, catabolism. no significant difference between the turnovers of human and monkey kininogens was observed ... | 1979 | 105015 |
| implications for adult roles from differential styles of mother-infant bonding: an ethological study. | ethological observations of maternal and infant behaviors of nine vervet monkey pairs (cercopithecus aethiops sabaeus) showed the effects of differential styles of early maternal responsiveness on later infant competence. those infants receiving the least amount of maternal responsiveness and the most time-off the mother in the first 3 months of development were more socially competent at 6 months of age. the results are discussed within current ethological "attachment" theories. the detachment ... | 1979 | 105083 |
| construction of a recombinant plasmid composed of b. subtilis leucine genes and a b. subtilis (natto) plasmid: its use as cloning vehicle in b. subtilis 168. | | 1978 | 105237 |
| characterization of plasmid transformation in bacillus subtilis: kinetic properties and the effect of dna conformation. | transformation of competent cells of bacillus subtilis with antibiotic resistance plasmid dna has shown that (a) competence for plasmid and chromosomal dna develops with similar kinetics; (b) dna linearized with a variety of restriction endonucleases does not transform; (c) ccc plasmid dna is inactivated for transformation by a single nick; (d) t4 ligase restores transforming activity to both nicked and linearized dna; (e) ccc relaxed dna is fully active in transformation; (f) the dna concentrat ... | 1979 | 105246 |
| [enzyme-kinetic studies on tissue sections of biopsy materials--a new diagnostic possibility for the detection of enzyme changes in the human small intestinal resorption epithelium]. | | 1978 | 105486 |
| [changes in the spectrum of disease-causing bacteria]. | | 1978 | 105494 |
| [determination of cholera vibrion enterotoxin by an aggregate hemagglutination method]. | | 1979 | 105503 |
| [cattle calcinosis in austria. vii. the significance of growth stages and harvesting (silage, hay) of golden oats (trisetum flavescens) for development of calcinosis]. | | 1978 | 105511 |
| case report: intestinal clearance of calcium and protein in waldenstrom's macroglobulinemia. | a 63-year-old man with waldenstrom's macroglobulinemia had severe steatorrhea, marked protein-losing enteropathy, and excessive endogenous fecal calcium clearance. the malabsorption and protein loss resulted in weight loss and hypoalbuminemia. in contrast, the striking enteric calcium loss was completely compensated by an increase in calcium absorption resulting in a positive calcium balance. | 1978 | 105640 |
| comparative in vivo nitrogen-15 nuclear magnetic resonance study of the cell wall components of five gram-positive bacteria. | the proton-decoupled 9.12 mhz 15n nmr spectra of 15n-labeled bacillus subtilis, bacillus licheniformis, staphylococcus auresu, streptococcus faecalis, and micrococcus lysodeikticus intact cells, isolated cells walls, and cell wall digests have been examined. the general characteristics of gram-positive bacteria 15n nmr spectra and described and spectral assignments are provided, which allow in vivo 15n nmr to be applied to a wide range of problems in bacterial cell wall research. the qualitative ... | 1979 | 105756 |
| anomalies of the human hyaloid system. | we describe two asymptomatic cases of persistent anomalies of the human hyaloid system. fluorescein angiography of a cyst of the hyaloid system shows leakage from the hyaloid vessels. | 1978 | 105788 |
| [experimental cholera in monkeys]. | the immune response to vibrio cholerae was studied in baboons, rhesus monkeys and marmosets inoculated by the oral, intraintestinal or intravenous route with various strains of v. cholerae. sera were collected from all animals on days 2, 6, 10, 17, 24, 32, 45 and 60 after infection. serum protein, immunoglobulins (iga, igg, igm), got, and alkaline phosphatases were determined. the results showed that baboons and rhesus monkeys were not susceptible to cholera infection under these experimental co ... | 1978 | 105813 |
| studies on autoregulation of prolactin secretion from perifused rat pituitary glands in the basal and thyrotropin-releasing hormone-stimulated states. | | 1978 | 105892 |
| maternal separation vs removal from group companions in rhesus monkeys. | | 1979 | 106065 |
| [lithium and pregnancy (author's transl)]. | the problem has been considered of the action of lithium salts on the progress of pregnancy and on the product of the conception. lithium can bring about serious troubles in morphogenesis in invertebrate animals. the results obtained in mammals in laboratory experiments differ from species to species but it seems that these animals can be given about 8 to 9 times the levels of lithium that are used in man without causing teratogenic effects. a statistical review of the children born to human mot ... | 1978 | 106083 |
| [isolation and general characteristics of a group of pseudomonas aeruginosa temperate phages]. | eighteen temperate phages were isolated from 38 natural strains of pseudomonas aeruginosa. the phages belong to five heteroimmune groups according to the ability of lysogenic variants of the strains pao1 and pat2 to exclude the growth of the superinfecting phage. phages of the ii and v immunity groups are serologically similar; the remaining phages are not inactivated by antisera against phages b26 (ii group) and k1338 (v group). prophages of the ii, iv, and v groups are induced by uv for vegeta ... | 1979 | 106221 |
| [xerophytic microorganisms multiplying under conditions close to martian ones]. | the xerophytic cultures bacillus megaterium and mycococcus ruber can grow in the imitated martian conditions. therefore, they are resistant to the extreme factors of the environment: the composition of atmosphere, low pressure, the maximum hygroscopicity of a substrate, periodic freezing-thawing. | 1979 | 106224 |
| [changes in certain biochemical parameters of rat skin following prolonged gamma irradiation after radioprotection]. | | 1978 | 106409 |
| the antinociceptive effect of intracerebroventricularly administered prostaglandin e1 in the rat. | it is generally accepted that prostaglandins (pgs) are nociceptive substances. however, earlier studies from this laboratory indicated that morphine analgesia, in the rat, was not only serotonin mediated, but involved pgs as well. several pg synthesis inhibitors were shown to inhibit morphine analgesia and pge1 was shown to potentiate the antinociceptive effect of morphine. intraperitoneal administration of pge1, but not pge2 and pgf2alpha, elicited antinociceptive effect per se, by the radiant ... | 1979 | 106425 |
| effects of atenolol and propranolol on human performance and subjective feelings. | in a double-blind, double crossover experiment, 18 healthy young men received over 3-day periods either 100 mg atenolol, 80 mg propranolol, or placebo. the subjects underwent various motor and cognitive tests 18 h after each last dose had been taken. propranolol significantly increased variability of a choice reaction-time task. scores on various subjective rating scales showed that propranolol had a larger mood elevating effect than atenolol. heart rate and blood pressure were significantly red ... | 1979 | 106432 |
| the metabolism and disposition of 3,4,4'-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (m. mulatta). | | 1978 | 106490 |
| [calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings]. | | 1978 | 106573 |
| congenital partial hemimelia tibia in a kitten. | | 1979 | 106597 |
| ultrastructural effects of chemical agents and moist heat on bacillus subtilis. i--effects on vegetative cells. | the ultrastructural alterations induced by treatment of vegetative bacillus subtilis cells with organic solvents, trichloroacetic acid (tca) and moist heat were examined by electron microscopy. organic solvents disorganize the membrane and change the asymmetric unit membrane profile to a symmetric profile. they also lead to partial solubilization of the membrane and produce small or extensive gaps. membrane damaging activity increases in the following order: xylene = toluene less than octanol le ... | 1978 | 106754 |
| immunochemical studies on a yersinia enterocolitica o:9 lipopolysaccharide cross-reacting with brucella abortus and vibrio cholerae extracts. | the presence of two distinct lipopolysaccharides in yersinia enterocolitica o:9 is described: one isolated from the aqueous phase and one from the phenol phase (westphal system). the sugar moiety of the phenol phase lipopolysaccharide has been identified as being responsible for the serologic cross-reaction of y. enterocolitica o:9, brucella abortus and vibrio cholerae. the phenol phase antigen consists of glucose, galactose, glucosamine, 2-keto-3-deoxyoctonic acid, heptose, lipid a and a protei ... | 1978 | 106756 |
| trans-stilbene oxide: a new inducer of rat liver microsomal udp-glucuronyltransferase. | | 1979 | 106858 |
| carboxypeptidase of streptomyces griseus. implications of its characteristics. | | 1979 | 106886 |
| a monolayer study of the reaction of trinitrobenzene sulphonic acid with amino phospholipids. | the reaction of trinitrobenzene sulphonic acid with amino phospholipids, and in particular phosphatidylethanolamine has been studied by the monolayer technique. injection of trinitrobenzene sulphonic acid under a monolayer of amino phospholipid results in an increase in surface pressure. the rate and extent of the pressure change is greatly affected by the initial surface pressure, the fatty acid composition of the lipid, and the presence of other non-reactive lipids, especially negatively charg ... | 1979 | 106889 |
| inhibition of neisseria gonorrhoeae by normal human saliva. | saliva was found to be a powerful and specific inhibitor of neisseria gonorrhoeae. although 28 other species of bacteria were tested, including neisseria meningitidis, neisseria pharyngis var flava, neisseria lactamica, and neisseria catarrhalis, we failed to find any others sensitive to saliva under similar conditions. the physical properties of the inhibitory substance indicated that it might be salivary alpha-amylase. to test this hypothesis alpha-amylase was extracted from saliva and was sho ... | 1979 | 106919 |
| [effects of chemotherapeutic agents on strains of neisseria meningitidis isolated in bohemia during 1970-1976]. | | 1979 | 106970 |
| effects of nitroglycerin on echocardiographic measurements of left ventricular wall thickness and regional myocardial performance during acute coronary ischemia. | the effects of nitroglycerin on regional left ventricular performance, assessed by echocardiographic techniques, were investigated in anesthetized, open-chest dogs during acute myocardial ischemia. during transient occlusion of the left anterior descending coronary artery, there was end-diastolic thinning and marked reduction in systolic thickening in the central ischemic zone. similar changes of lesser degree were noted in the border zone. the normal zone was unaffected. infusion of nitroglycer ... | 1979 | 106986 |
| liver transplantation. | | 1979 | 107000 |
| contralateral projection of primary afferent fibers to mammalian spinal cord. | | 1979 | 107041 |
| influence of alvogyl on the healing of extraction wound in man. | eight volunteer patients free of any systamic disease underwent extraction of two teeth on the same day. one extraction socket was packed with alvogyl, the other served as a control wound. biopsies for histological assessment were taken from both sockets 1 and 2 weeks after extraction. histological study revealed the normal sequence of wound healing in the sockets allowed to heal spontaneously. on the other hand, the signs of retarded wound healing (acute inflammatory infiltrate, persistent gran ... | 1979 | 107131 |
| rubella virus maturation and production in two host cell systems. | when inoculated at the same moi, vero cells released a larger amount of infectious rubella virus into the culture medium than did bhk21 cells, however, bhk21 cells (in monolayer or in suspension) produced more intracellular infectious virus than vero cells when tested 24 h after infection. maturation of the virus in bhk21 cells occurred at the plasma membrane and, in a larger quantity, in the cytoplasm (golgi apparatus and vacuoles). viral particles consisted of an electron-dense core (32 nm) su ... | 1979 | 107143 |
| overall pathway of mononucleosome production. | five electrophoretically distinguishable classes of mononucleosomes (mi, mii, ...mv) are produced upon treatment of mammalian nuclear chromatin with micrococcal nuclease. these five forms differ in their initial dna lengths, relative mass proportions, stability, contents of histone h1, and presence of certain nonhistone proteins. a new "chromatin fingerprinting" technique has been developed in order to trace nuclease-mediated interconversions between these mononucleosomes and their polynucleosom ... | 1979 | 107168 |
| acetylated methylmannose polysaccharide of streptomyces griseus. locations of the acetyl groups. | the positions of esterification of the 4 to 5 acetyl residues in the acetylated methylmannose-containing polysaccharide from streptomyces griseus have been established by the methyl replacement technique, wherein ester substituents are specifically replaced with methyl ether substituents. the newly incorporated methyl groups were distinguished from 3-o-methyl groups by the use of polysaccharide containing radioactively labeled endogenous methyl groups. the positions of methyl group localization ... | 1979 | 107171 |
| alcohol, malnutrition and liver disease. | | 1979 | 107268 |
| dietary protein, aryl hydrocarbon hydroxylase and chemical carcinogenesis in rats. | | 1979 | 107295 |
| percutaneous nitroglycerin absorption in rats. | percutaneous nitroglycerin absorption was studied in shaved rats by monitoring unchanged plasma drug concentrations for up to 4 hr. drug absorption from the neat liquid state or from an alcoholic solution was considerably poorer than that from a commercial ointment. this observation was unanticipated since the driving force for percutaneous drug absorption was assumed to be drug thermodynamics. potential artifacts such as drug volatilization from the skin, reduction of surface area through dropl ... | 1979 | 107313 |
| partial purification of heat-labile hemolysin from pseudomonas aeruginosa. | | 1978 | 107353 |
| [a patient with meningococcal pericarditis without signs of meningitis]. | | 1979 | 107462 |
| [preparation of extracellular ribonuclease from bacillus subtilis]. | the paper describes a method for isolating alkaline ribonuclease from the culture liquid bacillus subtilis kp 349 which involved: submerged cultivation of the producer on complex and synthetic nutrient media with optimized rnase activity, acid treatment of the total culture liquid, and filtration through perlite. further treatment may include either spray drying of the culture liquid filtrate or its concentration in a vacuum evaporator, dialysis of the concentrate against distilled water, and d ... | 1978 | 107517 |
| radical scavenging as the mechanism for stimulation of prostaglandin cyclooxygenase and depression of inflammation by lipoic acid and sodium iodide. | certain radical-trapping reducing agents have been shown to stimulate prostaglandin biosynthesis in vitro (1--6) and to depress phorbol myristate acetate-induced mouse ear edema (16). the increased prostaglandin synthesis resulted from influences on the cyclooxygenase. to ascertain whether these alterations were due to direct interaction with the enzyme or to indirect scavenging of the oxidant released during pgg2 reduction, we report the effects of lipoic acid and sodium iodide. both of these a ... | 1978 | 107544 |
| fat-induced jejunal inhibition of gastric acid secretion and release of pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, and vasoactive intestinal polypeptide in man. | the effect of intrajejunal (i.j.) infusion of fat on meal-stimulated gastric acid secretion and release of pancreatic glucagon (pg), enteroglucagon (eg), gastric inhibitory polypeptide (gip), and vasoactive intestinal polypeptide (vip) was studied in seven healthy volunteers. i.j. fat markedly inhibited meal-stimulated acid secretion as compared to a control study with i.j. saline infusion. the acid inhibition was accompanied by augmental plasma concentrations of eg, gip, and vip but not of pg, ... | 1979 | 107575 |
| a three month inhalation toxicity study in the squirrel monkey (saimiri sciureus) with terbutaline sulfate (bricanyl). | a study of the subacute toxicity of inhaled terbutaline sulfate was performed in the squirrel monkey (saimiri sciureus). 3 groups of monkeys were exposed 1 h daily 7 days/week for 3 months to terbutaline sulfate aerosols at concentrations of 0.039, 0.185 and 0.799 mg terbutaline/litre of air respectively. a fourth group was a chamber control receiving air only. the following clinical parameters were evaluated: physical appearance and behavior, weight gain, ophthalmoscopic appearance, electrocard ... | 1978 | 107616 |
| the viability of cryopreserved aegyptianella pullorum carpano, 1928 in the vector argas (persicargas) walkerae kaiser and hoogstraal, 1969. | | 1979 | 107668 |
| pituitary-thyroid function in spironolactone treated hypertensive women. | four weeks high dose spironolactone treatment (aldactone searle, 100 mg q. i. d.) significantly enhanced the tsh (delta max. 8.5 +/- 4.1 vs. 4.6 +/- 3.1 microunits/ml, p less than 0.05) and t3 (delta max. 32 +/- 27 vs. 11 +/- 16 ng/100 ml, p less than 0.05) responses to an intravenous trh/lh-rh bolus injection in 6 eumenorrhoeic euthyroid hypertensive women, without affecting basal serum tsh, t3 or t4 levels or the basal and stimulated lh, fsh and prolactin values (p greater than 0.10). the mean ... | 1979 | 107696 |
| adverse hemodynamic and ultrastructural changes in dog hearts subjected to protein-calorie malnutrition. | in the absence of thiamine deficiency, the specific effects of protein-calorie malnutrition on left ventricular (l.v.) function are unknown. mature beagle dogs of both sexes were subjected to a hypocaloric, nitrogen-poor diet which resulted in a weight loss of approximately 40% after seven weeks. following preparation of this nutritional model, myocardial contractility was assessed acutely by obtaining isovolumetric l.v. contractions on cardiopulmonary bypass at constant heart rate, mean aortic ... | 1979 | 107775 |
| pseudomonas orbital cellulitis. | a 3-month-old infant being treated for bronchitis developed a rapid onset but otherwise typical orbital cellulitis. because gram-negative infections and septicemia are common occurrences in the newborn nursery, this patient was given systemic gentamicin and ampicillin. sinus x-rays were not attempted. two days after treatment the eyelids were opened. a strikingly large corneal ulcer with perforated globe and endophthalmitis was found. pseudomonas aeroginosa was cultured from the blood, conjuncti ... | 1979 | 107805 |
| experimental transmission of wuchereria bancrofti to monkeys. | infective larvae of wuchereria bancrofti from laboratory-raised culex pipiens fatigans and aedes togoi mosquitoes fed on human volunteers in jakarta, indonesia (j strain) and kinmen island, china (k strain) were introduced into taiwan monkeys (macaca cyclopis) by subcutaneous inoculation, by foot puncture, or by permitting infected mosquitoes to feed weekly on the monkeys. some animals were splenectomized and others were treated with varying regimens of immunosuppressants. necropsy was done on m ... | 1979 | 107818 |
| glyconamides as inhibitors of human beta-glucosidases and beta-galactosidases. | | 1979 | 107857 |
| two functional types of neurons in the superficial layers of monkey superior colliculus. | | 1978 | 107871 |
| imbalanced protein and appetite. | free amino acid concentration in the plasma of rats fed on different diets were compared. the diets contained 7 g protein/100 g furnished by: casein, or common corn, or opaque 2 corn, or eggalbumin, or gelatin. a protein free diet was also included. the results showed that imbalance of the protein diet influenced the appetite; whenever the ne/e aminoacid ratio increased, body development, appetite and plasma albumin decreased. an inverse correlation between the ne/e of free aminoacids of the pla ... | 1978 | 107928 |
| monocyte-induced increase in osmotic fragility of human red cells sensitized with anti-d alloantibodies. | the mechanism by which human monocytes increase the osmotic fragility of red cells sensitized with rhesus alloantibodies anti-d was studied in vitro. both the increase in osmotic fragility and the lysis of red cells by monocytes were enhanced by cytochalasin b and were inhibited by hydrocortisone. these effects were similar to the effects of these agents on lysosomal enzyme release by monocytes. however, hydrocortisone was completely ineffective when added 1 h after mixing monocytes and sensitiz ... | 1978 | 107958 |
| [effect of pancreatic dnase on dna synthesis in bacillus subtilis]. | an addition of pancreatic dnase to the cultural medium is found to stimulate dna synthesis and proliferation of bacillus subtilis cells. pancreatic dnase induces a single-stranded disruption of bac. subtilis dna, which may act as a mechanism of dna synthesis increase and of the culture growth acceleration. | 1979 | 107976 |
| enzyme immobilization by radiation-induced polymerization of 2-hydroxyethyl methacrylate at low temperatures. | enzyme immobilization by radiation-induced polymerization of hydrophilic glass-forming monomers, such as 2-hydroxyethyl methacrylate, was studied. enzyme radiation damage could be sufficiently retarded at low temperatures. the immobilized enzyme activity yield was markedly higher at low temperature than at higher temperature polymerization. at low temperatures the polymerized composite had a porous structure owing to ice crystallization which depends on the monomer concentration. it was deduced ... | 1979 | 107982 |
| isolation of listeria monocytogenes from animals in the sudan. | | 1979 | 107996 |
| induction of reaginic (ige) gonococcal antibodies in the rat by a common antigen of neisseria gonorrhoeae. | an antigen (zab) common to neisseria gonorrhoeae was prepared by stepwise elution of a crude gonococcal antigen (za) from columns of diethylaminoethyl cellulose employing 0.02 m phosphate buffers, ph 7.6, containing increasing concentrations of sodium chloride. rats immunized with zab produced reaginic (ige) antibody which cross-reacted with za prepared from eight gonococcal strains by the passive cutaneous anaphylaxis (pca) test. heating of the sera at 56 degrees c for 4 h destroyed the pca act ... | 1979 | 108009 |
| [antiarrhythmic properties of 3-(2-hydroxy-3 isopropylamino-propoxy)-3 phenyl-2 isoindolinone-1, (rs, sr) in the dog]. | in the dog, 3-(2-hydroxy-3 isopropylamino-proxy)-2-phenyl-1-isoindolinone (rs, sr) possesses an anti-arrhythmic activity similar to that of quinidine but at dose levels 2 to 6 times lower than in the case of the latter compound. furthermore, in contrast to quinidine, at the dose levels where the antiarrhythmic activity is well observed, the compound is devoid of hypotensive activity and of depressive action on cardiac contractility. the first clinical studies of this compound have shown its usef ... | 1979 | 108025 |
| new data on the physiopathogenesis of experimental generalized epilepsies. | | 1978 | 108076 |
| the association of the serotonin-sensitive aryl acylamidase with acetylcholinesterase in the monkey brain. | | 1979 | 108100 |
| fascioloides magna: development in selected nonruminant mammalian hosts. | | 1979 | 108129 |
| [the behavior of 7, 12-dimethylbenz(a)anthracene (dmba)-induced mammary tumors in rats during pregnancy and lactation and hormone levels in the pituitary and plasma (author's transl)]. | in order to keep a long-term lactation in primiparous sd strain rats with dmba-induced mammary tumors, 5 pups aged 5 to 10 days were exchanged every 10 days. fsh, lh and prolactin (prl) in pituitary tissues and fsh, lh, prl, estradiol (e2) and progesterone (prg) in plasma were determined during pregnancy (1,2 and 3-week), at paturition (0 to 12 hours after parturition) and during lactation (1,2,3,4,5 and 6-week). experimental rats were divided into 6 groups according to the lactating period (non ... | 1979 | 108141 |
| inhibition of 7,12-dimethylbenz[alpha]anthracene-induced mammary tumorigenesis in rats by a synthetic protease inhibitor, n,n-dimethylamino-(p-(p'-guanidinobenzoyloxy)) benzilcarbonyloxyglycolate. | oral administration of n,n-dimethylamino-(p(p'-guanidinobenzoyloxy))-benzilcarbonyloxy glycolate depressed induction of breast tumors in rats by a single intravenous injection of 7,12-dimethylbenz[alpha]anthracene. the latent period was delayed in the group fed on a diet supplemented with n,n-dimethylamino-(p(p'-guanidinobenzoyloxy))benzilcarbonyloxy glycolate. administration of this compound for 40 days after 7,12-dimethylbenz[alpha]anthracene also significantly reduced the average weight of tu ... | 1978 | 108169 |
| a solid-phase radioimmunoassay for bacterial lipopolysaccharide. | a radioimmunoassay for e. coli 055:b5 lipopolysaccharide (lps) is described. the lps was derivatised by two new methods and subsequently radiolabeled with 125i to a specific activity of 2-4 mci/mg without apparent loss in its biophysical, immunological or biological activities. using antibody-coated polystyrene tubes, a solid-phase radioimmunoassay was developed with a sensitivity of 10-500 ng/ml of lps. | 1979 | 108200 |
| macaca assamensis as a new host for experimental plasmodium knowlesi infection. | | 1978 | 108217 |
| mechanism of folate transport in lactobacillus casei: evidence for a component shared with the thiamine and biotin transport systems. | lactobacillus casei cells have been shown previously to utilize two separate binding proteins for the transport of folate and thiamine. folate transport, however, was found to be strongly inhibited by thiamine in spite of the fact that the folate-binding protein has no measurable affinity for thiamine. this inhibition, which did not fluctuate with intracellular adenosine triphosphate levels, occurred only in cells containing functional transport systems for both vitamins and was noncompetitive w ... | 1979 | 108244 |
| role of heme in synthesis and membrane binding of succinic dehydrogenase in bacillus subtilis. | a 5-aminolevulinic acid-requiring mutant of bacillus subtilis was isolated. when the mutant is shifted from medium containing 5-aminolevulinic acid to medium lacking this growth factor, the bacteria continued to grow at undiminished rate for about three generations. the membranes from these bacteria contained severely reduced amounts of cytochrome. the mutant was used to study the role of heme synthesis on synthesis and membrane binding of succinic dehydrogenase (sdh). the amount of sdh in whole ... | 1979 | 108259 |
| glucose-triggered germination of bacillus megaterium spores. | triggering of germination in bacillus megaterium qm b1551 spores with d-glucose was studied. first, the interaction of glucose with spores for less than 1 min resulted in triggering almost 90% of the spores after the glucose was removed by dilution. therefore only a brief time is needed for glucose to trigger germination, and then the continuous presence of glucose is not necessary. detectable uptake of glucose began 2 to 3 min after absorbance loss started, and a non-metabolizable glucose analo ... | 1979 | 108260 |
| dissociation and reconstitution of membranes synthesizing the peptidoglycan of bacillus megaterium. a protein factor for the polymerization step. | cholate-solubilized bacillus megaterium membranes can be reconstituted by dialysis in the presence of magnesium ion to regain approximately 12% of the original peptidoglycan synthetic activity. bio-gel a-5m filtration of the solubilized components shows that all of the compounds necessary for peptidoglycan synthesis can be dissociated into material with a molecular weight of less than approximately 68,000. using this reconstitution system, an assay has been developed for a new protein factor, pg ... | 1979 | 108266 |
| a bacillus subtilis mutant requiring dipicolinic acid for the development of heat-resistant spores. | a bacillus subtilis mutant is described which forms heat-resistant spores only in the presence of external dipicolinic acid (dpa). the mutation, dpa-1, is localized in a new sporulation locus, linked to pyra. the dpa-1 strain is unable to synthesize dpa but can incorporate external dpa. the amount of dpa incorporated, the frequency of heat-resistant spores and their degree of resistance are all dependent on the concentration of external dpa. spores of dpa- 1 strains exhibit normal resistance to ... | 1979 | 108357 |
| effect of n-trifluoroacetyl derivatives of amino acids and amino acid analogs on microbial antitumor screen. | eighteen trifluoroacetyl derivatives of amino acids and of amino acid analogs were prepared and tested for growth-inhibitory activity using a lactobacillus casei system as a prescreen for antitumor activity. of the compounds tested, the trifluoroacetyl derivatives of o-, m-, and p-fluorophenylalanine and of beta-3-thienylalanine showed modest activity; trifluoroacetyl derivatives of phenylalanine and of beta-2-thienylalanine showed marginal activity. the activity exhibited by the active trifluor ... | 1979 | 108385 |
| effects of mechanical and chemical stimulation of fine muscle afferents upon primate spinothalamic tract cells. | 1. injections of algesic chemicals were made into the arterial circulation of the triceps surae muscles in anaesthetized monkeys. 2. the responses of a sample of primary muscle afferents suggest that what is known about the activation of muscle afferents in the cat by algesic agents applies also to the monkey. one exception to this is the activation of many group i afferents by kcl in the monkey, but not in the cat. 3. many spinothalamic tract cells were powerfully excited by the intra-arterial ... | 1979 | 108391 |
| galvanized caging as a potential factor in the development of the "fading infant" or "white monkey" syndrome. | four rhesus females and their infants were kept in galvanized enclosures, and three were kept in stainless steel caging. all four offspring in the galvanized enclosures developed achromotrichia, alopecia, and weakness that varied from modererate to severe while the three infants in stainless steel cages were clinically normal. plasma copper, zinc, and iron values as well as liver copper and zinc values of the infants were compared for the two types of caging. plasma copper values were significan ... | 1978 | 108464 |
| medical and surgical approach to laryngeal air sacculitis in a baboon caused by pasteurella multocida. | air sacculitis was diagnosed in a chronically chaired baboon, papio anubis. pasteurella multocida was repeatedly isolated from the air sac for a period of 1 year. the condition was characterized by the continuous accumulation of either mucoserous or purulent fluid. biopsies of the air sac taken during the course of the disease initially revealed goblet cell hyperplasia. later a subepithalial mononuclear or polymorphonuclear infiltrate and necrosis was the predominate finding. medical therapy was ... | 1978 | 108467 |
| comparison of ketmine with the combination of ketamine and xylazine for effective anesthesia in the rhesus monkey (macaca mulatta). | the addition of xylazine to ketamine hydrochloride was found to enhance analgesia, anesthesia, and muscle relaxation in rhesus monkeys. at 0.10 ml/kg body weight, this combination provided adequate anesthesia for such procedures as cisternal puncture, lumbar spinal puncture, insertion of urinary catheters, finger amputations, and tattooing. the combination of ketamine and xylazine did depress the heart rate, respiration rate, and body temperature more than the administration of ketamine alone. t ... | 1978 | 108468 |
| secondary thrombocytopenia following phenobarbital treatments in a rhesus monkey (macaca mulatta). | a rare adverse reaction due to phenobarbital (10 mg/kg/day for 11 days) developed in a rhesus monkey (macaca mulatta). clinical signs and measured hematological parameters correlated closely with descriptions of thrombocytopenia. following cessation of phenobarbital, the monkey recovered within 11 days. five months after initial thrombocytopenia, the monkey was challenged again with phenobarbital (10 mg/kg/day for 11 days). appearance and progression of clinical signs were identical to the initi ... | 1979 | 108473 |
| role of physiologic autoantibody in the removal of senescent human red cells. | the mechanism by which mononuclear phagocytes distinguish mature "self" from senescent "self" was investigated. evidence is presented indicating that human mononuclear phagocytes distinguish senescent rbc from mature rbc on the basis of selective ig attachment to the membranes of senescent cells. this ig, eluted from senescent human rbc, was shown to be igg and free of other igs by immunodiffusion, immunoelectrophoresis, and polyacrylamide gel electrophoresis. the igg was polyclonal with respect ... | 1978 | 108480 |
| identification of 15-keto-9, 11-peroxidoprosta-5, 13- dienoic acid as a hematin-catalyzed decomposition product of 15-hydroperoxy-9, 11-peroxidoprosta-5, 13-dienoic acid. | a labile prostaglandin was isolated as one of the products generated from [1-14c] eicosatetraenoic acid incubated with sheep vesicular gland microsomes. the eicosatetraenoic acid metabolite amounted to ca. 16% of the total radiolabeled products. formation of this new prostaglandin was prevented when heat-denatured microsomes were employed or when incubation mixtures were supplemented with indomethacin or phenol. however, incubation of prostaglandin g2 (pgg2) with hematin in the presence or absen ... | 1979 | 108495 |