| [use of the neutralization test for mass population studies]. | the authors applied the antibody neutralization test (ant) for detection of causative agent of intestinal infections in feces of healthy population in turkmenia. some part of the material was studied in parallel with the aid of the ant and by the bacteriological method. as a result of comparison it appeared that in using the ant causative agents of intestinal infections were revealed much more frequently than by the bacteriological method; in this connection this serological method can be recomm ... | 1976 | 828825 |
| xylose lysine deoxycholate agar for the isolation of salmonella and shigella from clinical specimens. | xylose lysine deoxycholate (xld) agar was more efficient for the detection of shigella sonnei than salmonella-shigella (ss) agar and drigalski agar, xld was slightly more efficient for the detection of salmonellae by direct plating than ss agar. xylose lysine deoxycholate agar is proposed as the second selective plating medium for shigellae isolation. it is also a useful second selecting plating medium for the isolation of salmonellae serotypes, which form non-characteristic colonies on bismuth- ... | 1977 | 848209 |
| in vitro activity of cinoxacin, ampicillin, and chloramphenicol against shigella and nontyphoid salmonella. | the in vitro antibacterial activity of cinoxacin was compared with that of ampicillin and chloramphenicol against 26 strains of nontyphoid salmonella and 44 strains of shigella. cinoxacin was found to have a lower minimal inhibitory concentration than ampicillin and chloramphenicol against all salmonella and shigella sonnei strains. cinoxacin had minimal inhibitory concentrations similar to those of chloramphenicol but lower than those of ampicillin against shigella flexneri and s. boydii strain ... | 1977 | 856008 |
| genetic recombination of bacteriophage t7 dna in vitro. | we have demonstrated recombination of bacteriophage t7 dna in vitro. an extract of escherichia coli b cells infected with wild-type t7(t7+) is incubated with mature dna extracted from t7 phage. packaging of the exogenous dna within the phage head appears to be preceded by recombination of exogenously added dna with dna present in the extracts. in order to detect the recombination, we used an exogenous dna bearing a marker (ss-) such that progeny phage which have packaged this marker are able to ... | 1976 | 1062779 |
| isolation and identification of alpha1-antitrypsin as a component of normal and malignant human breast and other tissues. | alpha1-antitrypsin has been detected using radial immunodiffusion in the 90,000g supernatant fraction of malignant and adjacent normal human breast, colon, and anal tissue, as well as malignant lung, stomach, and ileum. immobilized chymotrypsin, bound to sepharose or affi-gel 10 has been utilized to separate 11 peaks of antiproteolytic activity by affinity chromatography of normal and malignant human breast tissue extracts. glycoproteins are associated with eight of the peaks. peak 1 contains pr ... | 1975 | 1081233 |
| ampicillin-resistant hemophilus sp. | | 1976 | 1082793 |
| nucleosides. 1. 9-(3'-alkyl-3'-deoxy-beta-d-ribofuranosyl)adenines as lipophilic analogues of cordycepin. synthesis and preliminary biological studies. | a series of lipophilic 9-(3'-alkyl-3'-deoxy-beta-d-ribofuranosyl)adenines of increasing chain length was synthesized from the corresponding branched sugars via titanium chloride catalyzed ribosylation of chloromercuri-6-benzamidopurine. enhanced growth inhibitory activity was observed against (ccrf-cem human lymphoblastic leukemia cells in culture as the length of the alkyl side chain in the sugar and the resultant lipophilic character of the nucleoside were increased. experiments involving inco ... | 1976 | 1087343 |
| [mixed epidemic of typhoid fever and shigellosis]. | | 1975 | 1089349 |
| antimicrobial resistance of shigellae isolated in michigan. | patterns of antimicrobial resistance were studied for 213 strains of shigellae isolated in rural and urban areas of michigan by quantitative techniques: 66% of these organisms were resistant to ampicillin, tetracycline, cephalexin, or chloramphenicol or had multiple resistance to various combinations of these antibiotics. the incidence of resistant organisms was higher in the detroit-wayne county area, which is the most urban part of the state. nalidixic acid and oxolinic acid were noted to be q ... | 1975 | 1089819 |
| [some immunoallergic tests in patients with ulcerative colitis]. | | 1975 | 1089962 |
| occurrence of the bacteriophage lambda receptor in some enterobacteriaceae. | in escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ... | 1975 | 1090748 |
| [sensitivity of different strains of e. coli and shigella to the inhibitory action of ploskirev's bactoagar]. | a study was made of the sensitivity of 190 strains of e. coli and 107 strains of shigellae of different serological types to the inhibitory action of ploskirev's bactoagar on the capacity of these bacteria to form colonies. the strains under study proved to be nonhomogenous in this respect: between different strains of e. coli there were revealed 10-, 100- and even 1000-fold differences by this property; the differences between shigellae strains were less marked--in over 90% of shigellae strains ... | 1975 | 1092090 |
| [lysotypy of shigella sonnei (literature review)]. | | 1975 | 1092095 |
| [typing properties of bacteriophages isolated from sh. sonnei strains]. | on the basis of studying the lytic activity of eight bacteriophages the authors elaborated a scheme of bacteriophage typing of sh. sonnei consisting of nine bacteriophage types with two subtypes. in typing 2348 strains isolated in various cities of the ussr bacteriophage pattern of sh. sonnei was found to differ in different towns of the ussr. all the strains isolated repeatedly from the same patients were referred to the same bacteriophage type, this pointing to the stability of the type-deter ... | 1975 | 1092096 |
| [polyamines in species of microorganisms of the intestinal group]. | a study was made of polyamines (putrescine, spermidine and spermin) in various representatives of the enterobacteriaceae family--e. coli, sh, sonnei, sh. flexneri and s. typhi abdominalis. all the strains under study contained putrescine and spermidine, and many shigella and salmonella strains had spermin in addition. there were significant differences in the quantitative content of polyamines in the individual species. by the ratio of nitrogen of polyamine to phosphorus of nucleic acid it is po ... | 1975 | 1092098 |
| waterborne shigellosis at a public school. | in november 1972 an outbreak of gastrointestinal illness occurred at a public school in stockport, iowa. one hundred ninety-four (72%) of 269 pupils and 14 (16%) of 23 staff members were affected. the etiologic agent was a strain of shigella sonnei resistant to multiple antimicrobials. waterborne transmission of shigellosis was documented epidemiologically and by isolation of the organism from the school water system. ninety-seven (14%) of 698 of the students' household contacts developed diarrh ... | 1975 | 1092157 |
| superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1. | the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ... | 1975 | 1094073 |
| [nature of the reactions in vaccination against intestinal infections]. | | 1975 | 1094698 |
| [antibiosis shown by a strain of byssochlamys nivea westling, 1909. iii. chromatographic characteristics and isolation of the active fraction]. | early papers revealed that culture filtrate of byssochlamys nivea has antibiotic properties. active filtrate of b. nivea is extracted with ethyl acetate. paper chromatography is carried out on whatman no. 1; thin-layer chromatography is carried out on kieselgel; visualization with bioautographic technique reveals a single spot. ethyl acetate extract is passed through silicic acid-celite column. each isolated fraction is tested for antibiotic activity. only one supports this activity; a crystalli ... | 1975 | 1095929 |
| shigella outbreak in amos cottage, hospital for retarded children. | | 1975 | 1095939 |
| [characteristics of serum immunoglobulins in sonne dysentery in children]. | | 1975 | 1096467 |
| shigella strains associated with infantile diarrhea in the kaohsiung area. | in 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ... | 1975 | 1097211 |
| [dynamics of dysenteric diseases, caused by sh. sonnei of different enzymatic and conditional colicinogenotypes, in kharkov in 1965-1972]. | results of studying the enzymatic (by maltose, rhamnose and xylose) properties of 9277 freshly-located sh. sonnei strains isolated in kharkov in 1965-1972 showed that they were referred to 14 enzymatic types (a, b, c, d, e, f, g, k, l, m, n, o, p, q). the strains under study were additionally--within the range of each of the enzymatic type-divided into 8 conditioned coli phi,cinogen types (i-viii) by their sensitivity to colicines of the indicator e. coli, k12 and b cultures. subdivision of the ... | 1975 | 1098335 |
| bactericidal and opsonic activities of normal sheep serum against gram-negative bacteria. | the bactericidal and opsonic activities of normal sheep serum against 9 smooth and 4 rough strains of gram-negative bacteria were measured. three smooth strains-escherichia coli 3662, salmonella typhimurium, and salmonella gallinarum-were resistant to the bactericidal action of normal sheep serum with or without complement. six smooth strains-e coli o78:k80(b), salmonella arizonae, proteus inconstans, klebsiella pneumoniae, salmonella stanley, and salmonella abortus-equi-were moderately sensitiv ... | 1975 | 1098532 |
| [survival of microorganisms of the intestinal group and staphylococcus aureus on synthetic polymeric materials]. | | 1975 | 1098966 |
| colicin types of shigella sonnei in relation to antibiotic resistance. | colicin typing of 436 strains of shigella sonnei isolated in dallas during a 10-year period was performed to determine whether resistance to ampicillin was associated with a single strain or was widespread among all s. sonnei types. one hundred ninety-three strains collected during a period of eight and one-half years when ampicillin resistance was 1.6% were available for retrospective review. during the last one and one-half years of study, 20.6% of the 243 strains that represented almost all ... | 1975 | 1099149 |
| specific antibodies and heterologous antigensin monofactor sera. | a concentrated monofactor serum 9 (wellcome lot k 8028) precipitated against proteins from 2 different strains of salmonella enteritidis and from a strain of s. dublin, as well as against the proteinic moiety of the somatic antigen from s. typhi 0 901; no polysaccharide from the strains, sharing factor 9, precipitated against this serum. a concentrated monofactor serum 20 (wellcome lot k 6733) precipitated against the proteins from s. emek (8, 20), but not against its polysaccharide. a monofacto ... | 1975 | 1099401 |
| complement-mediated bactericidal system: evidence for a new pathway of complement action. | the early components of human complement (c1, c4, and c2) plus certain serum euglobulins will kill pathogenic strains of shigella sonnei. serum from patients with hereditary c3 deficiencies and specific antiserums to c3, c5, and c6 were utilized to demonstrate the absence of requirements for late-acting complement components in this unusual bactericidal system. | 1975 | 1101380 |
| [sensitivity of bacterial flora to antibiotics according to data from a clinical hospital]. | antibiotic sensitivity of e. coli o-124, salmonella and shigella sonnei isolated from patients during 1968-1972 was studied with the disc method. increase in the resistance levels to monomycin and neomycin in e. coli o-124 was observed. sensitivity of salmonella and shigella sonnei to some antibiotics did not practically change. | 1975 | 1101809 |
| epidemiological and bacteriological studies on an outbreak of sh. sonnei. | | 1975 | 1104983 |
| [biological peculiarities of the etiology in connection with various clinical manifestations of sonne dysentery in children]. | | 1975 | 1105369 |
| [certain cytochemical indicators of neutrophils in acute dysentery sonnei in children]. | | 1975 | 1105382 |
| typing of shigella sonnei colicins by means of specific indicators. | an enlarged and perfected scheme of typing of shigella sonnei colicins is based on the knowledge of types of colicins produced by abbott's types as well as by newly discovered and determined colicin types. a set of specific indicators prepared from e. coli k13 hfrr, e. coli c6 and shigella sonnei by a selection of suitable mutants and recombinations was used for the typing. seven new colicin types were determined on typing shigellae found in the field. type 9a produces colicins e3, ia, type 16 p ... | 1975 | 1106068 |
| [immune serum globulins in acute dysentery in children]. | | 1975 | 1106085 |
| [study of the sensitivity of shigella to ectericide]. | | 1975 | 1106086 |
| [study of the virulence of shigella sonnei isolated from persons with different forms of dysenteric infection]. | possible ranges of virulence of sh. sonnei strains isolated from the patients and carriers in the foci of sonne dysentery, supposedly with the same source of infection, were studied. sh. sonnei strains isolated from carriers proved to be less virulent than the strains isolated from patients with the clinical manifestation of the infection. a hypothesis was put forward explaining some aspects of carrier state in sonne dysentery, which most probably was explained by the refracterity of the macroor ... | 1975 | 1106091 |
| [intracellular parasitism of shigella in patients with dysentery]. | bioptic specimens of the mucosa of the distal portion of the colon in patients with dysentery, caused by flexner and sonne shigellas, were studied by luminescent-serological and electron-microscopy methods. in the cells with unchanged ultrastructure no shigellas were detected. intracellular localization of shigellas was observed only in cases of deep irreversible alterations in the ultrastructure of the cells. | 1975 | 1106366 |
| colicin typing of shigella sonnei isolated in northern taiwan. | eighty-eight strains of shigella sonnei isolated in northern taiwan during the period of 1970-1974, were studied for their colicin types by a modified method of abbott and shannon. as a result, 67(76%) typable and 21(24%) non-typable strains were found. the prevalent colicin types of s. sonnei in northern taiwan were types 15(52%) and 6(15%), followed by types 8(3%), 11(3%) and 12(3%). other types were not found. | 1975 | 1106960 |
| observations on environmental contamination in a microbiological laboratory. | contamination of a laboratory environment with pathogenic or non-pathogenic micro-organisms may be relevant to safety of technicians and quality of technical performance. two widely separated incidents in 1968 and 1974 initiated a study of aspects of the laboratory environment. water-baths, water of syneresis and portions of salmonella cultures spurting out of the sterilizing flame were examined. the water of water-baths was shown to be contaminated from the fluid cultures incubated in them. thi ... | 1976 | 1107415 |
| [antimicrobial and antineoplastic properties of alkaloids of greater celandine and their thiophosphamide derivatives]. | | 1975 | 1107767 |
| [an analysis of meat products as possible factors responsible for transmission of dysenterial toxic infections]. | the paper carries experimental data derived from a bacteriological analysis of infected minced meat products for the presence of shigella sonnei and for ascertaining technological stages non-compliance with whose proper course presents the greatest epidemiological hazards. the procedures employed in analyzing infected meat products are shown to be sufficiently sensitive, for they enable one to count shigella dysenteriae in numbers of 102-106/g, depending upon the degree of total bacterial contam ... | 1975 | 1108439 |
| [adjuvant action of nonspecific inflammation in immunizing guinea pigs vis the keratoconjunctival sac with shigella sonnei somatic antigens]. | | 1975 | 1108517 |
| [biological characteristics of biochemical variants of sh. sonnei]. | | 1975 | 1108532 |
| [shigella in seawater and in an estuary. iii. determination in vitro of the survival time of s. sonnei ycd in seawater]. | | 1975 | 1108731 |
| [prodigiosin in the overall therapy of dysentery and in the prevention of intrahospital viral respiratory infection in children]. | prodigiozan was tested in complex therapy of children with acute dysentery. comparison of clinical symptoms, specific immunogenesis and child sanation periods from shigella in the child groups treated (80) and non-treated (74) with prodigiozan showed that prodigiozan lowered the rate of intrahospital acute respiratory virus infection, provided more favourable dysentery progression, more tensed specific immunity and the patient clearance from shigella. | 1975 | 1108774 |
| [potassium distribution and glycogen metabolism under muscle load in rats. ii. changes in muscle and liver lactate, glycogen and water]. | | 1975 | 1116029 |
| antimicrobial resistance of shigella isolated in new york city in 1973. | one hundred and two shigella sonnei and fourteen s. flexneri strains isolated from individual patients in new york city hospitals were investigated for antibiotic resistance. the s. sonnei showed 60% resistance to ampicillin and 58% to tetracycline and streptomycin. s. flexneri showed no ampicillin resistance but 50% resistance to tetracycline. there were marked differences in resistance of s. sonnei between hospitals which were not explainable by ethnic or socio-economic differences in the pati ... | 1975 | 1155925 |
| time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats. | previous neuroanatomical work has shown that lesions of the entorhinal cortex in adult rats cause the commissural projections to spread from their normally restricted locus in the inner molecular layer approximately 40-50 mum into the outer molecular layer (that is, into the zone deafferented by the lesion). in the present study we measured the effects of the entorhinal lesion on the distribution of short-latency potentials elicited by commissural stimulation in the molecular layer. studies with ... | 1975 | 1175043 |
| [diagnostic problems in gout in a 44-year-old man]. | | 1976 | 1251615 |
| antimicrobial susceptibilities of shigellae isolated in houston, texas, in 1974. | one hundred seventy-three strains of shigellae (113 shigella sonnei, 56 s. flexneri, and four others) isolated in houston during 1974 were tested for susceptibility to commonly used and newer antimicrobial agents. forty-five percent of s. sonnei strains were susceptible to ampicillin, whereas 93% of s. flexneri strains were susceptible to that agent. s. sonnei and s. flexneri strains were equally susceptible to tetracycline (35 and 33%, respectively). all 173 strains were uniformly susceptible t ... | 1976 | 1267426 |
| [the effect of shigella sonnei strains opposite in their virulence on different links in the immune system]. | for the first time different action of s. sonnei strains, opposite in their virulence, on hematopoiesis and the functional activity of t- and b-lymphocytes has been shown. the hematopoiesis-disturbing action of virulent shigellae is manifested by their capacity, more pronounced than similar capacity of an avirulent (vaccine) strain, for stimulating the processes of endo- and exocolony formation, the proliferation of hematopoietic stem cells and their migration to the blood. the effect produced b ... | 1992 | 1279912 |
| effect of natural and synthetic immunomodulators on the synthesis of interferon by peritoneal cells of mice. | the effect of different natural and synthetic immunomodulators on the spontaneous interferon (ifn) synthesis by freshly isolated resident peritoneal cells of balb/c, nzb and c3h mice was investigated. actinomycetal glycolipids isolated from curtobacterium betae, faenia rectivirgula, rothia dentocariosa and saccharopolyspora hirsuta at the concentration 1-20 micrograms/ml were found to potentiate the ifn synthesis by the peritoneal cells of balb/c mice. similar results were obtained when dsrna, l ... | 1992 | 1279963 |
| characterization of a lipopolysaccharide encoded by a recombinant shigella sonnei plasmid in escherichia coli k-12. | the genetic information to synthesize the s-specific region of shigella sonnei phase i lipopolysaccharide (lps) is localized on a 180 kb plasmid which is lost quite readily. a recombinant plasmid derivative remaining stable in the bacteria was shown to determine the s-specific region of the lps which is completely identical with that of a s. sonnei phase i strain following transfer in escherichia coli k-12. however, the length control in polysaccharide biosynthesis is lost at least partially. | 1992 | 1284653 |
| dysentery due to shigella infection. | | 1992 | 1285156 |
| an outbreak of foodborne shigella sonnei infection. | | 1992 | 1285187 |
| [the intoxication syndrome in acute dysentery]. | | 1992 | 1293830 |
| [the effect of short-term adaptation to high-altitude conditions on human blood serum lipoproteins]. | | 1992 | 1307051 |
| in vitro repair of double-strand breaks accompanied by recombination in bacteriophage t7 dna. | a double-strand break in a bacteriophage t7 genome significantly reduced the ability of that dna to produce viable phage when the dna was incubated in an in vitro dna replication and packaging system. when a homologous piece of t7 dna (either a restriction fragment or t7 dna cloned into a plasmid) that was by itself unable to form a complete phage was included in the reaction, the break was repaired to the extent that many more viable phage were produced. moreover, repair could be completed even ... | 1992 | 1309515 |
| optimal stimulation of paralyzed muscle after human spinal cord injury. | muscle properties change profoundly as a result of disuse after spinal cord injury. to study the extent to which these changes can be reversed by electrical stimulation, tibialis anterior muscles in complete spinal cord-injured subjects were stimulated for progressively longer times (15 min, 45 min, 2 h, and 8 h/day) in 6-wk intervals. an index of muscle endurance to repetitive stimulation doubled (from 0.4 to 0.8), contraction and half-relaxation times increased markedly (from 70 to approximate ... | 1992 | 1317372 |
| osmy, a new hyperosmotically inducible gene, encodes a periplasmic protein in escherichia coli. | a new osmotically inducible gene in escherichia coli, osmy, was induced 8- to 10-fold by hyperosmotic stress and 2- to 3-fold by growth in complex medium. the osmy gene product is a periplasmic protein which migrates with an apparent molecular mass of 22 kda on sodium dodecyl sulfate-polyacrylamide gels. a genetic fusion to osmy was mapped to 99.3 min on the e. coli chromosome. the gene was cloned and sequenced, and an open reading frame was identified. the open reading frame encoded a precursor ... | 1992 | 1317380 |
| [shigellosis in children of the ix region of chile: clinical and epidemiologic aspects and antibiotic sensitivity]. | ninety four children with diarrhea and a positive stool culture for shigella, hospitalized at the hospital regional de temuco, were studied. forty six percent of patients were less than two years old. forty two percent of microorganisms were resistant to ampicillin, 45% to trimethoprim/sulfamethoxazole, 8% to tetracycline and none to chloramphenicol. isolated species were shigella flexneri 83% and shigella sonnei 17%. seventy nine percent of patients had fever, 60% dysentery and 21.3% seizures. ... | 1992 | 1340946 |
| [bacteriology of shigella isolated in a tropical zone chu]. | from 1981 to 1991, five hundred eighty one shigella's strains were isolated in the laboratories of the chu fann of dakar. they represent 24.8 per cent of enteropathogen agents and 4.3 per cent of diarrhoeae causative agents. shigella flexneri was predominant (71%), following by shigella dysenteriae (14.5%), shigella sonnei (11.4%) and shigella boydii (2.5%). in pediatric hospital 90 per cent of strains were isolated between 1 and 5 years age; in adults, the pic was found from 20 to 30 years. fiv ... | 1992 | 1345084 |
| sexual transmission of htlv infections in southern india. | | 1992 | 1346809 |
| molecular epidemiology of shigella infections in israel. | the dnas of shigella sonnei or shigella dysenteriae type 1 strains isolated in outbreaks of shigellosis or in sporadic cases were analysed by restriction fragment length polymorphism (rflp). southern blots of the dnas of 36 s. sonnei isolates digested by 8 restriction enzymes were hybridized with an escherichia coli rrna probe. the s. sonnei strains were unexpectedly diverse in their rflp. antibiotypes of the same isolates showed clusters of strains corresponding to the various outbreaks. on the ... | 1992 | 1356821 |
| beta adrenergic receptor desensitisation may serve a cardioprotective role. | the aim was to test the hypothesis that beta adrenoceptor desensitisation is a form of cardioprotection whereby the myocardium is protected from the injurious effects of excessive adrenergic stimulation by isoprenaline. | 1992 | 1360332 |
| pyrizinostatin: a new inhibitor of pyroglutamyl peptidase. | | 1992 | 1361487 |
| immunochemical characterization of citrobacter strain pcm 1487 o-specific polysaccharide- and core oligosaccharide-protein conjugates. | o-specific-polysaccharide and core oligosaccharide were isolated from citrobacter strain pcm 1487 lipopolysaccharide and purified. the polysaccharide was selectively devoid of 4-deoxy-d-arabinohexose residues. covalent conjugates of the modified o-specific polysaccharide and of the core oligosaccharide with tetanus toxoid were prepared. immunochemical characterization of these conjugates proved that they are strong immunogens. using monospecific rabbit antisera raised against the conjugates, the ... | 1992 | 1376131 |
| monitoring of antibiotic resistance in shigellae isolated in the netherlands 1984-1989. | during surveillance of antimicrobial resistance in shigella strains isolated in the netherlands from 1984 to 1989 and forwarded to the national institute of public health and environmental protection for typing, sensitivity to twelve antimicrobial agents was assessed. high rates of resistance to the older drugs of choice in treating shigellosis were found, i.e. ampicillin and trimethoprim-sulfamethoxazole. ampicillin resistance varied from 33 to 53% among shigella flexneri strains and from 10 to ... | 1992 | 1396730 |
| [plasmid analysis and antibiotic resistance pattern measurement of shigella in chengdu]. | a total of 81 strains of shigella isolated from sporadic cases and cases in an outbreak of shigella sonnei infection was analysed by plasmid profiles and antibiotic resistance patterns. the strains had a high resistance patterns. the strains had a high resistance of ampicillin, tetracycline, trimethoprim-sulfamethoxazole and chloramphenicol; while 97.2% of the strains were susceptible to gentamicin, kanamycin. the results showed that 50% of the strains harbored plasmid patterns within each speci ... | 1992 | 1398620 |
| an analysis of the quantitative relationship between oral temperature and severity of illness in experimental shigellosis. | the relationship between oral temperature and other parameters of illness was examined in 139 adult volunteers infected experimentally with shigella sonnei. in subjects developing clinical disease, peak temperature correlated positively with total number of signs and symptoms other than fever (rxy = .71, p < .001), stool volume (rxy = .41, p < .001) and number of stools produced during the illness (rxy = .46, p < .001). peak temperature correlated negatively with incubation period (rxy = -.34, p ... | 1992 | 1402032 |
| an international foodborne outbreak of shigellosis associated with a commercial airline. | to determine the source of an international outbreak of shigellosis associated with consumption of food served by a minnesota-based airline. | 1992 | 1433760 |
| [the characteristics of cryptosporidiosis prevalence in nizhni novgorod province]. | a total of 4070 patients with acute intestinal diseases were tested for cryptosporidiosis in 1989, 1806 of these without diarrhea (controls), 286 of them working at slaughter houses, milk-packing plants and dairy plants, 192 subjects with a history of contacts with cryptosporidiosis patients in the focus of the disease, and 7 animals. cryptosporidiosis was responsible for 3.2% of acute intestinal conditions in children; cryptosporidia oocysts were not detected in adults or healthy subjects. the ... | 1992 | 1435583 |
| [lipopolysaccharide changes in smooth-type avirulent shigella in comparison with initial virulent strains]. | the comparative study of the lipopolysaccharides (lps) of virulent and avirulent strains of s. sonnei, phase i (smooth colonies), has been made. electrophoresis of lps and subsequent densitometry of electrophoregrams have revealed the increase of the fraction of long 0-chains with a considerable number of recurring elements in 2 out of 3 lps preparations obtained from avirulent shigellae. in mice immunized with these lps preparations a considerably greater number of antibody-producing cells can ... | 1992 | 1441805 |
| activities of newer fluoroquinolones against shigella sonnei. | the activities of six fluoroquinolones were determined for 117 separate strains of shigella sonnei. the order of increasing activity (mics for 90% of strains tested) was enoxacin (0.25 micrograms/ml), temafloxacin (0.032 micrograms/ml), sparfloxacin (0.016 micrograms/ml), ci-960 (0.008 micrograms/ml), ciprofloxacin (0.008 micrograms/ml), and pd-131628-2 (0.008 micrograms/ml). these data, along with results of killing and mutational rate studies, showed that all six fluoroquinolones were highly i ... | 1992 | 1444317 |
| synthesis and antiplatelet activities of n-arylmethyl-3,4-dimethylpyrano[2,3-c]pyrazol-6-one derivatives. | a series of new 1- and 2-arylmethyl-3,4-dimethylpyrano[2,3-c]pyrazol-6-one derivatives were synthesized and examined for their antiplatelet activities. some of these compounds showed significant inhibitory activities. among them, 1-phenylmethyl-3,4-dimethylpyrano[2,3-c]pyrazol-6(1h)-one (4a), 2-(2'-methoxyphenyl)methyl-3,4-dimethylpyrano[2,3-c]pyrazol-6(2h)- one (3e) and 2-(3'-methoxyphenyl)methyl-3,4-dimethylpyrano[2,3-c]pyrazol-6-(2h) - one (3f) were the most effective. these inhibitors acted ... | 1992 | 1446375 |
| inhibition of shigella sonnei by lactobacillus casei and lact. acidophilus. | the protective effect of feeding milk fermented with a mixture of lactobacillus casei and lact. acidophilus against shigella sonnei was studied. there was a 100% survival rate in mice fed for 8 d with fermented milk and then dosed orally with sh. sonnei. the survival rate in control mice was approximately 60% after 21 d. colonization of the liver and spleen with sh. sonnei was markedly inhibited by pretreatment with fermented milk. differences in cell counts of 2-3 log units between treated and ... | 1992 | 1447056 |
| concentration of milk secretory immunoglobulin a against shigella virulence plasmid-associated antigens as a predictor of symptom status in shigella-infected breast-fed infants. | we conducted a prospective, community-based study of healthy breast-fed mexican infants to determine the protective effects of anti-shigella secretory iga antibodies in milk. milk samples were collected monthly, and stool culture specimens were obtained weekly and at the time of episodes of diarrhea. nineteen breast-fed infants were found to have shigella flexneri, shigella boydii, or shigella sonnei in stool samples. ages of the 10 infants with symptomatic infection and the nine with asymptomat ... | 1992 | 1447644 |
| [the immunocorrective therapy of patients with acute dysentery]. | | 1992 | 1455821 |
| [the excretion of shigella antigens in persons recovering from dysentery]. | shigella antigens can be detected in the excreta of convalescents after dysentery for a long time. most frequently these antigens occur in feces, less frequently in urine and rarely in saliva. according to indirect data, s. flexneri 1-6 antigens can be detected in excreta for a longer period after convalescence than s. sonnei antigens. when antigen indication is used for the diagnosis of dysentery and epidemiological analysis is carried out, one should bear in mind the length of the agent persis ... | 1992 | 1455962 |
| [the etiological structure of shigellosis in the former ussr--an indicator of the activity of the main routes of infection transmission]. | the data on the etiological structure of shigella infections in the ussr in 1988-1989 are presented. the study showed the dominating role of s. flexneri with s. sonnei also retaining great importance in shigella infections. the process of the liquidation of s. dysenteriae and s. boydii infections began in some large cities. the domination of dysentery caused by s. flexneri and a high typhoid rate, particularly in central asia, were due to poor water supply of the population. the spread of dysent ... | 1992 | 1455964 |
| protection from shigella sonnei infection by immunisation of rabbits with plesiomonas shigelloides (svc 01). | plesiomonas shigelloides, an organism commonly found in water, is only rarely associated with diarrhoea in man. p. shigelloides serotype o:17 (svc o1), which is antigenically similar to shigella sonnei, was found to be neither virulent nor toxic for rabbits. rabbits immunised by feeding with p. shigelloides (svc o1) were completely protected against an oral challenge with 10(10) cells of s. sonnei but non-immunised rabbits were not. p. shigelloides (svc o1) may be a useful vaccine strain for shi ... | 1992 | 1460657 |
| [diagnosis of acute diarrheal infections]. | | 1992 | 1460834 |
| [the effect of a ribosomal shigella sonnei vaccine on cellular immune reactions]. | the influence of s. sonnei ribosomal vaccine on hematopoiesis, t- and b-cell-mediated immune reactions has been studied in the course of the development of experimental vaccinal process. the vaccine stimulated hematopoiesis, that was characterized by a dose-dependent increase in colony-forming units in the spleen (cfus), a rise in cfus in the blood and bone marrow and an increase in the pool of proliferating stem cells in bone marrow, shortly after injection. a pronounced immunostimulating effec ... | 1992 | 1466169 |
| [the theoretical and practical interpretations of the basic manifestations of the epidemic process in shigellosis]. | | 1992 | 1466177 |
| [the characteristics of the colonization resistance of the intestines in conventional animals with a history of clinical death]. | after modeling the terminal state caused by the acute loss of blood in rats their intestinal microflora was studied, as was their resistance to colonization. decreased resistance to colonization was registered early after resuscitation (up to 3 days), which was confirmed by the translocation of bacteria into internal organs, decreased number of lactobacilli in the contents of the small intestine and elevated level of enterobacteria in the intestine. disturbances in resistance to colonization was ... | 1992 | 1466180 |
| [bacillary dysentery--1990]. | | 1992 | 1475396 |
| ultrastructural alterations of brain cortex in rat following intraperitoneal administration of mercuric chloride. | intraperitoneal administration of a single dose (6 mg/kg body weight) of mercuric chloride (hgcl2) results in ultrastructural changes in brain cortex of the rats. 18 hours after administration of hgcl2 the accumulation of dense deposits of mercury in nerve and glial cell cytoplasm was observed. the quantity of microglia in neuropil was also increased in this experimental group. we postulate that these cerebral macrophages can play an important role in the process of intoxication, too. 5 days aft ... | 1992 | 1479187 |
| [multiyear observations of the dynamic epidemic process in sonne dysentery in a small district of vladimir province]. | on the basis of the epidemiological analysis of morbidity data for several years the many-sided dynamic characterization of the epidemic process of sonne dysentery in a small district is presented. as revealed by this analysis, the epidemic process developed in the presence of residual activity of the water factor; this activity was mediated by transmission of this infection through milk products contaminated in the course of their manufacture and distribution. the possibility of appearance of a ... | 1992 | 1481603 |
| dna adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for dna adduct-based human cancer risk assessment. | | 1992 | 1489923 |
| in vitro studies on the growth of shigella sonnei by lactobacillus casei and lact. acidophilus. | the inhibitory effect of lactobacilli on growth of shigella sonnei was studied. the effect was not due to ph alone, as addition of hydrochloric, lactic or acetic acids to culture media did not inhibit the normal growth of the shigellas. the degree of inhibition was measured by disc assay and showed that the inhibitory substance(s) can be extracellular and diffusible, varying the degrees of inhibition depending on the media tested. when broth was inoculated with mixed cultures of lactobacillus an ... | 1992 | 1490909 |
| [territorial differences in the nature of the etiological structure of shigellosis--a pattern or chance?]. | | 1992 | 1496882 |
| presence of specific immunoglobulin a-secreting cells in peripheral blood after natural infection with shigella sonnei. | the appearance of antigen-specific immunoglobulin a (iga) antibody-secreting cells (ascs) following natural infection with shigella sonnei during a common-source outbreak caused by this organism was evaluated in a modified enzyme-linked immunosorbent assay (elispot). a mean iga asc value of 2,131.6/10(6) cells against homologous s. sonnei lipopolysaccharide (lps) was detected in blood samples obtained from patients with bacteriologically proven s. sonnei shigellosis 5 and 10 days after the onset ... | 1992 | 1500527 |
| [etiological structure of dysentery in the republic of armenia]. | in this work materials on the etiological structure of shigella infections at different territories of armenia are presented. four shigella species have been found to circulate in armenia. the dominating etiological agent is s. flexneri with s. sonnei also playing an important role. the serological picture of s. flexneri is characterized by the prevalence of subserovar 2a. | 1992 | 1509848 |
| [the correspondence theory and etiological structure of shigella infections]. | | 1992 | 1509850 |
| [sensitivity of shigella to antibiotics]. | three hundred and twenty two shigella cultures isolated from dysentery patients within 1986-1989 were tested with the use of standard paper disks for their sensitivity to levomycetin, streptomycin, tetracycline, monomycin, neomycin, kanamycin, erythromycin, gentamicin, carbenicillin, ampicillin, oxacillin, methicillin and doxycycline. the number of the cultures belonging to shigella sonnei amounted to 85.1 per cent of the total number of the strains studied. 91.9, 89.5, 87.3, 87.3, 80.1 and 80.1 ... | 1992 | 1514848 |
| titres of class-specific antibodies against shigella and salmonella lipopolysaccharide antigens in colostrum and breast milk of costa rican, swedish and vietnamese mothers. | enzyme immunoassays (eia) were used to estimate titres of class-specific antibodies against purified and chemically defined phenol-water-extracted lipopolysaccharide (lps) antigens of salmonella serogroup b (bo), shigella dysenteriae type i, plesiomonas shigelloides (the same o-antigen as shigella sonnei) and shigella flexneri y. titres in colostrum and breast milk of swedish, vietnamese and costa rican mothers from various socioeconomic conditions were compared. the antibodies were mainly of th ... | 1992 | 1522329 |
| [clinical evaluation of a new carbapenem, meropenem, in infants and children]. | a new carbapenem antibiotic, meropenem (mepm), was evaluated for its safety and efficacy in 33 infants and children. mepm was effective in all the 32 evaluable cases including 4 cases of bacterial meningitis and 5 cases of pseudomonas aeruginosa infections. the mean half life of plasma concentrations of mepm was 0.84 +/- 0.09 hours after 30 minutes intravenous drip infusion. mild diarrhea (2 cases), transient elevation of transaminases (8 cases), and transient eosinophilia (2 cases) were associa ... | 1992 | 1522678 |
| risk factors for suicide attempts in a human immunodeficiency virus screening program. | | 1992 | 1539099 |
| drug resistance and plasmid profile of shigellae in taiwan. | one hundred and twenty-eight shigella strains isolated from newborn and infant human faecal specimens at kaohsiung medical college hospital in taiwan were serogrouped, serotyped and examined for drug-resistance patterns and for the presence of plasmids. forty-seven per cent of the isolates were found to belong to the shigella sonnei serogroup, 41% to the s. flexneri group, 9% to the s. boydii group and 3% to the s. dysenteriae group. the serotype with the greatest number of strains was s. sonnei ... | 1992 | 1547844 |
| pulsatile growth hormone secretion during the breeding season in male reindeer and its association with hypophagia and weight loss. | male deer reduce food intake and lose weight during the breeding season (rut) in autumn. growth hormone (gh) is lipolytic in ruminants; therefore, pulsatile gh secretion was measured in three young reindeer (rangifer tarandus tarandus) bulls during the natural period of weight loss during rut. blood samples were withdrawn through a jugular cannula every 20 min for 16 hr on 5 occasions from late summer to early winter in unanaesthetised animals. the deer were group fed a pelleted concentrate rati ... | 1992 | 1563616 |