| Equine Pre-Implantation Conceptuses Express Neuraminidase 2 - A Potential Mechanism for Desialylation of the Equine Capsule. | During the second and third week of pregnancy, the equine conceptus is covered by an acellular glycoprotein capsule. This capsule contains glycoproteins resembling those of the mucin family with sialic acid making up a high proportion of the carbohydrate. Coinciding with conceptus fixation, a marked decline in sialic acid content of the capsule occurs, which has been proposed to contribute to cessation of conceptus mobility. Herein, we describe the expression of neuraminidase 2 (NEU2) by pre-imp ... | 2011 | 22022932 |
| Management of hindlimb proximal suspensory desmopathy by neurectomy of the deep branch of the lateral plantar nerve and plantar fasciotomy: 155 horses (2003-2008). | Reasons for performing study: Neurectomy of the deep branch of the lateral plantar nerve and plantar fasciotomy have become accepted as methods of treatment of proximal suspensory desmopathy (PSD), but there are limited long-term studies documenting the outcome. Objectives: To describe long-term follow-up in horses with PSD alone or with other injuries contributing to lameness and poor performance, including complications, following neurectomy and fasciotomy. Methods: Follow-up information was a ... | 2011 | 21883416 |
| lipopolysaccharide infusion up-regulates hepcidin mrna expression in equine liver. | hepcidin has been found to be the key regulator of iron metabolism that leads to hypoferremia during inflammation. recent work has shown that equine hepcidin is predominantly expressed in the liver of horses. in this study, hepcidin gene expression was determined in the liver and bone marrow of six healthy horses after iv infusion of escherichia coli o55:b5 lps. the il-6 gene expression was also determined in liver and bone marrow samples. clinical and laboratory evaluations were measured at mul ... | 2011 | 21926164 |
| evidence of infection with h4 and h11 avian influenza viruses among lebanese chicken growers. | human infections with h5, h7, and h9 avian influenza viruses are well documented. exposure to poultry is the most important risk factor for humans becoming infected with these viruses. data on human infection with other low pathogenicity avian influenza viruses is sparse but suggests that such infections may occur. lebanon is a mediterranean country lying under two major migratory birds flyways and is home to many wild and domestic bird species. previous reports from this country demonstrated th ... | 2011 | 22046370 |
| an attenuated eiav vaccine strain induces significantly different immune responses from its pathogenic parental strain although with similar in vivo replication pattern. | the eiav (equine infectious anemia virus) multi-species attenuated vaccine eiav(dlv121) successfully prevented the spread of equine infectious anemia (eia) in china in the 1970s and provided an excellent model for the study of protective immunity to lentiviruses. in this study, we compared immune responses induced by eiav(dlv121) to immunity elicited by the virulent eiav(ln40) strain and correlated immune responses to protection from infection. horses were randomly grouped and inoculated with ei ... | 2011 | 21893100 |
| Determination of sucrose in equine serum using liquid chromatography-mass spectrometry (LC/MS). | Mucosal integrity may be objectively assessed by determination of the absorption of exogenous substances such as sucrose. Gas chromatography-mass spectrometry (GC/MS) and liquid chromatography-mass spectrometry (LC/MS) have been reported for the accurate quantification of low concentrations of sucrose in serum. LC/MS offered the advantage of high sensitivity and mass selectivity without the need for extensive sample derivatization required for GC/MS methods. However, the high polarity and non-vo ... | 2011 | 22024392 |
| Effect of estrogen replacement therapy on symptoms of depression and anxiety in non-depressive menopausal women : A randomized double-blind, controlled study. | The efficacy of estrogen replacement therapy (ERT) for mood disturbances associated with menopause has yet to be firmly established. The objective of this study was to investigate the efficacy of ERT for improving mood and anxiety of non-depressive postmenopausal women. This double-blind, randomized, placebo-controlled study involved two treatment groups: one receiving conjugated equine estrogens (CEEs; 0.625 mg/day) and the other placebo, for six cycles of 28 days each. Subjects were hysterecto ... | 2011 | 22016254 |
| Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials. | Microcin C (McC) (1) is a potent antibacterial compound produced by some Escherichia coli strains. McC functions through a Trojan-Horse mechanism: it is actively taken up inside a sensitive cell through the function of the YejABEF-transporter and then processed by cellular aminopeptidases. Processed McC (2) is a non-hydrolysable aspartyl-adenylate analog that inhibits aspartyl-tRNA synthetase (AspRS). A new synthesis is described that allows for the production of a wide variety of McC analogs in ... | 2011 | 21855353 |
| Effect of equestrian therapy and onotherapy in physical and psycho-social performances of adults with intellectual disability: a preliminary study of evaluation tools based on the ICF classification. | Purpose: To assess the effects of equestrian rehabilitation (ER) and onotherapy (Ono) on physical and psycho-social performances of subjects affected by intellectual disability (ID), and to develop a measurement tool based on the International Classification of Functioning Disability and Health-Children and Youth (ICF-CY). Methods: A tool based on the ICF-CY classification was designed to evaluate subjects undergoing equine rehabilitation within a bio-psychosocial approach. A simplified version ... | 2012 | 21988646 |
| Antimicrobial activity of the surface coatings on TiAlZr implant biomaterial. | This study is devoted to antimicrobial activity of new surface coatings on TiAlZr. Ti alloys such as TiAlZr are used as implant biomaterials, but, despite the good behavior of such alloys in simulated conditions, bacterial infections appear after the introduction of an implant into the body. The infections are typically caused by the adherence and colonization of bacteria on the surfaces of the implants. The study presents preparation and surface morphology characterization of coatings obtained ... | 2011 | 21889399 |
| transtracheal aspiration and infusion in the horse. | transtracheal access enables researchers to obtain diagnostic samples from or infuse materials into the lower respiratory tract. this column describes transtracheal aspiration and infusion of horses. | 2011 | 21857643 |
| differentiation of meat samples from domestic horses (equus caballus) and asiatic wild asses (equus hemionus) using a species-specific restriction site in the mitochondrial cytochrome b region. | recent studies suggest that asiatic wild asses (equus hemionus) are being increasingly poached in a commercial fashion. part of the meat is believed to reach the meat markets in the capital ulaanbaatar. to test this hypothesis, we collected 500 meat samples between february and may 2006. to differentiate between domestic horse (equus caballus) and wild ass meat, we developed a restriction fragment length polymorphism (rflp) assay based on the polymerase chain reaction (pcr). we amplified and seq ... | 2006 | 22059088 |
| simple media and conditions for inter-laboratory transport of campylobacter jejuni isolates. | background: campylobacter jejuni is one of the most important agents of zoonotic disease. production as well as companion animals can be the infectious source for campylobacteriosis in humans. hence, epidemiological research on animal colonization, survival in food of animal origin, and human campylobacteriosis is of high priority. as such studies involve worldwide co-operations and should include further typing of isolates in reference centers, using a reliable method for transportation is esse ... | 2011 | 22029851 |
| effects of oral administration of energy drinks on blood chemistry, tissue histology and brain acetylcholine in rabbits. | energy drinks are canned or bottled carbonated beverages that contain large amounts of caffeine and sugar with additional ingredients, such as b-vitamins, amino acids and herbal stimulants. previous reports have shown that consumption of large amounts of these energy drinks may result in adverse health consequences. | 2011 | 21913538 |
| characterization of cytokines associated with th17 cells in the eyes of horses with recurrent uveitis. | objective equine recurrent uveitis (eru) is a spontaneous disease that is the most common cause of blindness in horses, affecting up to 15% of the horse population. th17 cells are a major cell population driving the pathogenesis in several mouse models of autoimmune inflammation, including experimental autoimmune uveitis. the purpose of this study is to investigate the role a th17 cell-mediated response plays in the pathogenesis of eru. procedure banked, davidson's-fixed equine globes histopat ... | 2011 | 22051225 |
| identification of dengue-specific b-cell epitopes by phage-display random peptide library. | dengue is the most important human viral disease transmitted by arthropod vectors. the availability of random peptide libraries (rpl) displayed on phage has provided a powerful tool for selecting sequences that mimic epitopes from microorganisms that are useful for diagnostic and vaccine development purposes. in this paper, we describe peptides that resemble the antigenic structure of b-cell epitopes of dengue virus identified from a phage-peptide library using human sera containing polyclonal a ... | 2009 | 22135507 |
| Important Role of Methionine 145 in Dimerization of Bovine ß-Lactoglobulin. | ß-Lactoglobulin (LG) contains nine ß-strands (strands A-I) and one a-helix. Strands A-H form a ß-barrel. At neutral pH, bovine LG (BLG) forms a dimer and the dimer interface consists of AB-loops and the I-strands of two subunits. On the other hand, equine LG (ELG) is monomeric. The residues 145-153 of BLG, which compose a dimer interface, are entirely different from those of ELG. The difference in the association states between BLG and ELG can be attributed to the residues 145-153. To confirm th ... | 2011 | 22210904 |
| Infection prevalences of common tick-borne pathogens in adult lone star ticks (Amblyomma americanum) and American dog ticks (Dermacentor variabilis) in Kentucky. | Rocky Mountain spotted fever, Lyme disease, and ehrlichiosis are tick-borne diseases that are reported annually in Kentucky. We conducted a survey to describe infection prevalence of tick-borne pathogens in Amblyomma americanum and Dermacentor variabilis ticks collected in Kentucky. During 2007-2008, we collected 287 ticks (179 D. variabilis and 108 A. americanum) from canine, feral hog, horse, raccoon, white-tailed deer, and human hosts in six counties in Kentucky. Ticks were screened for Ricke ... | 2011 | 21976578 |
| Influence of counting chamber type on CASA outcomes of equine semen analysis. | Reasons for performing study: Sperm motility is considered to be one of the key features of semen analysis. Assessment of motility is frequently performed using computer-assisted sperm analysis (CASA). Nevertheless, no uniform standards are present to analyse a semen sample using CASA. Objectives: We hypothesised that the type of counting chamber used might influence the results of analysis and aimed to study the effect of chamber type on estimated concentration and motility of an equine semen s ... | 2011 | 22150933 |
| sandwich elisa for detection of horse meat in raw meat mixtures using antisera to muscle soluble proteins. | a double-antibody sandwich elisa (enzyme-linked immunosorbent assay) has been successfully developed for the detection of defined amounts of horse meat (1-50%) in unheated meat mixtures. the assay uses horse-specific antibodies obtained by immunoadsorption of the crude horse antisera onto immobilised sarcoplasmic extracts from chicken, beef and pig to remove cross-reacting antibodies. the purified antibodies bound to a solid support sequester horse muscle soluble proteins from meat mixtures. fur ... | 1988 | 22055244 |
| time-dependent changes of cytokines mrna in bronchoalveolar lavage fluid from symptomatic recurrent airway obstruction-affected horses. | during an 18 day test, we measured the cytokine mrna expression (interleukin-1beta [il-1beta], interleukin-8 [il-8], interferon-gamma [ifn-gamma], tumor necrosis factor-alpha [tnf-alpha]) of cells from bronchoalveolar lavage fluid [balf] in five horses previously diagnosed with rao, before and during challenge exposure, and after the desensitization phase which involved dexamethasone treatment and environmental modification. simultaneously, the same cytokine mrna expression of cells from balf in ... | 2011 | 21957726 |
| cytogenetic and molecular characterization of y isochromosome in a 63xo/64xi(yq) mosaic karyotype of an intersex horse. | sex chromosome aberrations commonly lead to abnormal sexual development. here we cytogenetically and molecularly characterized y isochromosome in an intersex horse. blood lymphocyte analysis showed a mosaic karyotype with 96% 63,xo and 4% 64,xi(y) cells. molecular analysis of the isochromosome was carried out by fluorescence in situ hybridization and polymerase chain reaction with male-specific and pseudoautosomal markers from the horse y chromosome. we found that the isochromosome was monocentr ... | 2011 | 22005008 |
| gender effect on the relation between diabetes and hospitalization for heart failure. | cardiovascular risk among diabetic patients is at least twice as much the one for non-diabetic individuals and even greater when diabetic women are considered. heart failure (hf) is a common unfavorable outcome of cardiovascular disease in diabetes. however, since the comparison among sexes of heart failure prevalence in diabetic patients remains limited, this study is aimed at expanding the information about this point.we have evaluated the association between diabetes and hf by reviewing the m ... | 2011 | 21915814 |
| comparing the content of lipids derived from the eye lenses of various species. | the lipid content in the eye lens was analyzed and compared among various species in this study. the eye lens lipids of the following species were investigated: cow, horse, duck, and freshwater trout. additionally, the lipids derived from cataractous bovine lens and from cataractous human eye lens lipoprotein complexes were analyzed. the following lipid classes were detected in clear lenses: cholesterol, sphingomyelin, phosphatidylcholine, phosphatidyletanolamine, and phosphatidylserine. in cata ... | 2011 | 22038221 |
| Immunohistochemical localisation of progesterone and oestrogen receptors at the placental interface in mares during early pregnancy. | Previous reports documenting progesterone receptors (PR) and oestrogen receptors (ER) in the endometrium of early pregnant mares included specimens only up to Day 20 post ovulation. This study aimed to localise PR and ERa on equine feto-maternal tissues between Days 20 and 68 to encompass the period around fixation of the conceptus, development of the endometrial cups and attachment and initial interdigitation of the allantochorion. During early pregnancy mares had the same pattern of PR in the ... | 2011 | 22176887 |
| understanding and producing the reduced relative construction: evidence from ratings, editing and corpora. | tworating studies demonstrate that english speakers willingly produce reduced relatives with internal cause verbs (e.g., whisky fermented in oak barrels can have a woody taste), and judge their acceptability based on factors known to influence ambiguity resolution, rather than on the internal/external cause distinction. regression analyses demonstrate that frequency of passive usage predicts reduced relative frequency in corpora, but internal/external cause status does not. the authors conclude ... | 2007 | 22162904 |
| breast tenderness after initiation of conjugated equine estrogens and mammographic density change. | we examined the association between new-onset breast tenderness and change in mammographic density after initiation of conjugated equine estrogens (cee). we analyzed baseline, year 1 and 2 data from 695 participants of the women's health initiative estrogen + progestin (daily cee 0.625 mg + medroxyprogesterone acetate 2.5 mg [mpa] or placebo) and estrogen-alone (cee 0.625 mg or placebo) trials who participated in the mammogram density ancillary study. using multivariable repeated measures models ... | 2011 | 21979747 |
| evaluation of conventional pcr for detection of strongylus vulgaris on horse farms. | strongyle parasites are ubiquitous in grazing horses. of these, the bloodworm strongylus vulgaris is regarded as most pathogenic. increasing levels of anthelmintic resistance in strongyle parasites has led to recommendations of decreased treatment intensities, and there is now a pronounced need for reliable tools for detection of parasite burdens in general and s. vulgaris in particular. the only method currently available for diagnosing s. vulgaris in practice is the larval culture, which is la ... | 2011 | 21889849 |
| Colic in competing endurance horses presenting to referral centres: 36 cases. | Reasons for performing study: Colic is a common reason for elimination from equine endurance competitions and has recently been identified as the leading cause of mortality in this group of horses. Hydration and electrolyte derangements are often severe, but are probably related to endurance exercise and not necessarily the episode of colic. Better understanding of the causes of colic and the expected outcome is needed to guide treatment decisions in endurance horses. Objectives: To describe the ... | 2011 | 22050046 |
| Phylogenetic relationships of the Hucul horse from Romania inferred from mitochondrial D-loop variation. | The existence of the Hucul horse on Romanian territory has been documented from the very distant past; today Hucul is a unique breed that is part of the FAO Program for the Preservation of Animal Genetic Resources. We compared Hucul with several primitive European and Asiatic breeds in order to elucidate the origin of these horses. We analyzed a 683-bp mitochondrial DNA (mtDNA) D-loop fragment in a population of Hucul horses and compared the polymorphic sites with sequences from other pri ... | 2011 | 22057995 |
| influence of different mixing ratios on in-vessel co-composting of sewage sludge with horse stable straw bedding waste: maturity and process evaluation. | composting sewage sludge alone would reduce the decomposition efficiency due to free limited porosity in sludge. to alleviate this, the use of horse stable straw bedding waste (hsb) was evaluated as a co-composting material with sewage sludge in a 10 tonnes day(-1) in-vessel composter for a period of 7 days before curing in a static aeration pile. sludge was mixed with hsb at 1 : 1.5 (hsl) and 1 : 2.9 (lsl) on a fresh weight basis. after a composting period of 56 days, both mixing ratios demonst ... | 2011 | 21987410 |
| dynamic respiratory videoendoscopy in ridden sport horses: effect of head flexion, riding and airway inflammation in 129 cases. | dynamic upper airway obstruction (uao) is a cause of respiratory noise and sometimes poor performance in sport horses. riding, head flexion and airway inflammation may impact upper respiratory tract stability during exercise. | 2011 | 22180949 |
| Use of intravenous lipid emulsion to treat ivermectin toxicosis in a Border Collie. | A 2-year-old spayed female Border Collie was treated with IV lipid emulsion (ILE) after ingesting 6 mg/kg (2.73 mg/lb) of an equine ivermectin anthelmintic paste 8 hours prior to examination. | 2011 | 22044330 |
| Use of an inguinal approach adapted from equine surgery for cryptorchidectomy in dogs and cats: 26 cases (1999-2010). | OBJECTIVE-To determine whether a surgical technique used in cryptorchid horses can be used successfully to remove testicles retained in the inguinal region or abdominal cavity in dogs and cats. DESIGN-Retrospective case series. ANIMALS-22 dogs and 4 cats with cryptorchidism. PROCEDURES-In 1999 through 2010, 26 cryptorchid patients underwent surgery during which an incision was made over the inguinal ring and the undescended testicle was located for removal via identification of the vaginal proce ... | 2011 | 21985352 |
| Comparison of Gene-Specific DNA Methylation Patterns in Equine Induced Pluripotent Stem Cell Lines with Cells Derived From Equine Adult and Fetal Tissues. | Cellular pluripotency is associated with expression of the homeobox transcription factor genes NANOG, SOX2, and POU5F1 (OCT3/4 protein). Some reports suggest that mesenchymal progenitor cells (MPCs) may express increased quantities of these genes, creating the possibility that MPCs are more "pluripotent" than other adult cell types. The objective of this study was to determine whether equine bone marrow-derived MPCs had gene expression or DNA methylation patterns that differed from either early ... | 2011 | 21988203 |
| quest for the piroplasms in camels: identification of theileria equi and babesia caballi in jordanian dromedaries by pcr. | dna of two species of piroplasmids was detected in dromedaries during a survey of blood protozoans in jordan between 2007 and 2009. ten clinically healthy camels (10%) originating from three jordanian districts were found, using a pcr assay, to harbor theileria or babesia species in their blood and no mix infection was determined. analysis of the partial 18s rrna gene sequences of these parasites allowed their unambiguous identification as equine piroplasmids babesia caballi (n=6) and theileria ... | 2011 | 22186193 |
| mapping b-cell epitopes in equine rhinitis b viruses and identification of a neutralising site in the vp1 c-terminus. | erbovirus is a genus of the family picornaviridae and equine rhinitis b virus (erbv) is the sole species. erboviruses infect horses causing acute respiratory disease and sub-clinical and persistent infections. despite the high seroprevalence and worldwide distribution of these viruses, the pathogenesis and antigenic structure of the three erbv serotypes (erbv1, 2 and 3) is poorly understood. to characterise linear epitopes on erbv structural proteins, a set of fusion proteins were expressed in e ... | 2011 | 21930350 |
| Equine herpesvirus type 1 (EHV-1) mediated oncolysis of human glioblastoma multiforme cells. | The cytolytic animal virus equine herpesvirus type 1 (EHV-1) was evaluated for its oncolytic potential against five human glioblastoma cell lines. EHV-1 productively infected four of these cell lines and the degree of infection was positively correlated with glioma cell death. No human MHC-I was detected in the resistant glioma line, while infection of the susceptible glioma cell lines, which expressed human MHC-I, were blocked with antibody to MHC-I, indicating that human MHC-I acts as an EHV-1 ... | 2011 | 22205738 |
| my first 20 years in neuroscience. | intriguing facts were obtained in the first electrophysiological investigations (1964) that the action potentials (ap) produced by direct depolarization of the cell membrane in different species of mollusks showed specific relations to changes in external ionic composition. in helix neurons, the generation of ap was well maintained in sodium-free solutions with high calcium or barium content. the amplitude of the spike overshoot in the case was linearly related to the logarithm of calcium concen ... | 2011 | 21870522 |
| equine fetal sex determination using circulating cell-free fetal dna (ccffdna). | in this study, polymerase chain reaction (pcr) reamplification of the first pcr product (2nd-pcr) and a qpcr assay were used to detect the sex determining region y (sry) gene from circulating cell-free fetal dna (ccffdna) in blood plasma of pregnant mares to determine fetal sex. the ccffdna was isolated from plasma of 20 thoroughbred mares (5-13 y old) in the final 3 mo of pregnancy (fetal sex was verified after foaling). for controls, plasma from two non-pregnant mares and two virgin mares were ... | 2011 | 22000028 |
| effect of equine-assisted therapy on the postural balance of the elderly. | to determine whether equine-assisted therapy (hippotherapy) produces alterations in the balance of the elderly. | 2011 | 22002189 |
| Heminecrolysin, a potential immunogen for monospecific antivenom production against Hemiscorpius lepturus scorpion. | Serotherapy against Hemiscorpius (H.) lepturus scorpion sting is based on the administration of equine polyvalent antivenom prepared against a mixture of six venoms. In a previous study, we reported the identification of Heminecrolysin, a 33 kDa H. lepturus venom protein endowed with a sphingomyelinase D, hemolytic and dermonecrotic activities. We aimed herein to investigate the capacity of Heminecrolysin to generate antibodies able to neutralize the major physiopathological properties of H. lep ... | 2011 | 21967811 |
| Evaluation of a 14.5 kDa-Fasciola gigantica fatty acid binding protein as a diagnostic antigen for human fascioliasis. | The aim of the present study was to evaluate the efficiency of 14.5 kDa-Fasciola gigantica fatty acid binding protein (FABP) as a diagnostic antigen for human fascioliasis. 14.5 kDa FABP was isolated from the crude extract of adult F. gigantica worms by ion exchange chromatography followed by gel filtration chromatography and then analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis under reducing condition. Anti-FABP IgG polyclonal antibody (pAb) was generated in rabbits and pu ... | 2011 | 22113304 |
| A novel self-replicating chimeric lentivirus-like particle. | Successful live attenuated vaccines mimic natural exposure to pathogens without causing disease and have been successful against several viruses. However, safety concerns prevent the development of attenuated human immunodeficiency virus (HIV) as a vaccine candidate. If a safe, replicating virus vaccine could be developed, it might have the potential to offer significant protection against HIV infection and disease. Described here is the development of a novel self-replicating chimeric virus vac ... | 2012 | 22013035 |
| Single amino acid residue in the A2 domain of major histocompatibility complex class I is involved in the efficiency of equine herpesvirus-1 entry. | Equine herpesvirus-1 (EHV-1), an a-herpesvirus of the family Herpesviridae, causes respiratory disease, abortion, and encephalomyelitis in horses. EHV-1 utilizes equine MHC class I molecules as entry receptors. However, hamster MHC class I molecules on EHV-1-susceptible CHO-K1 cells play no role in EHV-1 entry. To identify the MHC class I molecule region that is responsible for EHV-1 entry, domain exchange and site-directed mutagenesis experiments were performed, in which parts of the extracellu ... | 2011 | 21949188 |
| Genetic analysis of the Venezuelan Criollo horse. | Various horse populations in the Americas have an origin in Spain; they are remnants of the first livestock introduced to the continent early in the colonial period (16th and 17th centuries). We evaluated genetic variability within the Venezuelan Criollo horse and its relationship with other horse breeds. We observed high levels of genetic diversity within the Criollo breed. Significant population differentiation was observed between all South American breeds. The Venezuelan Criollo horse ... | 2011 | 22002132 |
| Ultrastructural characterization of arterivirus replication structures: Reshaping the endoplasmic reticulum to accommodate viral RNA synthesis. | Virus-induced membrane structures support the assembly and function of positive-stranded RNA virus replication complexes. The replicase proteins of arteriviruses are associated with double-membrane vesicles (DMVs), which were previously proposed to derive from endoplasmic reticulum (ER). Using electron tomography, we performed an in-depth ultrastructural analysis of cells infected with the prototypic arterivirus equine arteritis virus (EAV). We established that the outer membranes of EAV-induced ... | 2011 | 22190716 |
| [Surgical treatment of nephroliths of the fused kidney]. | | 2011 | 22066251 |
| guest editorial: equine-assisted therapy. | | 2011 | 21938660 |
| concurrent lactation and pregnancy: pregnant domestic horse mares do not increase mother-offspring conflict during intensive lactation. | lactation is the most energy demanding part of parental care in mammals, so parent-offspring conflict arises over milk provided by the mother. in some species females commonly become pregnant shortly after parturition of previous young. this further intensifies mother-offspring conflict due to concurrent pregnancy and lactation. in equids it has been well established that pregnant females wean their foals earlier than non-pregnant ones. intensified mother-offspring conflict was presumed to assoc ... | 2011 | 21853024 |
| complete molecular genome analyses of equine rotavirus a strains from different continents reveal several new genotypes and a largely conserved genotype constellation. | in this study, the complete genome sequence of seven equine group a rotavirus (rva) strains (rva/horse-tc/gbr/l338/1991/g13p[18], rva/horse-wt/irl/03v04954/2003/g3p[12] and rva/horse-wt/irl/04v2024/2004/g14p[12] from europe; rva/horse-wt/arg/e30/1993/g3p[12], rva/horse-wt/arg/e403/2006/g14p[12], and rva/horse-wt/arg/e4040/2008/g14p[12] from argentina, and rva/horse-wt/zaf/eqrv-sa1/2006/g14p[12] from south africa) were determined. multiple new genotypes were identified and genotype numbers were a ... | 2011 | 22190012 |
| thoraco-omphalopagus conjoined twins in chamois-coloured domestic goat kids. | with 2 figures summary: conjoined twins have been observed in a wide range of mammalian and non-mammalian species; they are considered to be more common in bovine, less frequent in sheep and pig and extremely rare in horse and goat. a pair of female conjoined twins was delivered from a 2-year-old chamois-coloured domestic goat. post-mortem examination revealed two identical and symmetrical twins, fused from the manubrium sterni to the region just caudal to the umbilicus. the rib cages were conjo ... | 2011 | 22070788 |
| effects of long-term tibolone treatment on nuclear sex steroid hormone receptors and g-protein-coupled estrogen receptor-1 expression in the macaque uterus. | objective:: tibolone is an alternative hormone treatment for managing climacteric symptoms in postmenopausal women. the aim of this study was to determine the effects of long-term tibolone (tib) treatment in comparison with conventional hormone therapy on the expression and distribution of estrogen receptor (er) α, er-β, g-protein-coupled er-1 (gper), progesterone receptor (pr) a, prb, androgen receptor (ar), and syndecan-1 in the macaque uterus. methods:: eighty-eight cynomolgus macaques (macac ... | 2011 | 22027943 |
| disorders of sexual development in the domestic horse, equus caballus. | abnormalities of sexual development causing infertility in horses have been investigated since the early 1970's. conventional cytogenetic analysis by karyotyping has been the primary tool used to investigate these horses. abnormalities have a broad range, from a phenotypically normal mare with gonadal dysgenesis to a horse with ambiguous external genitalia and internal male and female organs. cytogenetic analysis can determine genetic sex but cannot identify mutations or deletions of genes invol ... | 2011 | 22095202 |
| Identification of H5N1-Specific T-Cell Responses in a High-risk Cohort in Vietnam Indicates the Existence of Potential Asymptomatic Infections. | Background. Most reported human H5N1 viral infections have been severe and were detected after hospital admission. A case ascertainment bias may therefore exist, with mild cases or asymptomatic infections going undetected. We sought evidence of mild or asymptomatic H5N1 infection by examining H5N1-specific T-cell and antibody responses in a high-risk cohort in Vietnam. Methods. Peripheral blood mononuclear cells were tested using interferon-? enzyme-linked immunospot T assays measuring the respo ... | 2012 | 22080094 |
| australian stringhalt in the uk. | | 2011 | 22039118 |
| clostridium difficile in dutch animals: their presence, characteristics and similarities with human isolates. | clin microbiol infect abstract: the presence and characteristics of clostridium difficile were investigated in 839 faecal samples from seven different animal species in the netherlands. the number of positive samples ranged from 3.4% (cattle) to 25.0% (dogs). twenty-two different pcr ribotypes were identified. among 96 isolates, 53% harboured toxin genes. all c. difficile isolates from pigs, cattle and poultry were toxinogenic, whereas the majority of isolates from pet animals consisted of non-t ... | 2011 | 21919997 |
| In vitro acute exposure to DEHP affects oocyte meiotic maturation, energy and oxidative stress parameters in a large animal model. | Phthalates are ubiquitous environmental contaminants because of their use in plastics and other common consumer products. Di-(2-ethylhexyl) phthalate (DEHP) is the most abundant phthalate and it impairs fertility by acting as an endocrine disruptor. The aim of the present study was to analyze the effects of in vitro acute exposure to DEHP on oocyte maturation, energy and oxidative status in the horse, a large animal model. Cumulus cell (CC) apoptosis and oxidative status were also investigated. ... | 2011 | 22076161 |
| Maternal recognition of pregnancy in the horse: a mystery still to be solved. | Maternal recognition of pregnancy in the horse is the sum of events leading to maintenance of pregnancy; in a narrow sense, maternal recognition of pregnancy refers to the physiological process by which the lifespan of the corpus luteum is prolonged. The horse is one of the few domestic species in which the conceptus-derived pregnancy recognition signal has not been identified. The presence of the conceptus reduces pulsatile prostaglandin F(2a) secretion by the endometrium during early gestation ... | 2011 | 22127001 |
| Surgical views - treating navicular syndrome in equine patients. | Navicular syndrome is a chronic, progressive condition affecting the navicular bone and bursa, deep digital flexor tendon (DDFT), and associated soft tissue structures composing the navicular apparatus. The treatment options for navicular syndrome are as varied as the proposed causes of the condition. The severity of clinical signs, intended use and workload of the horse, and owner compliance with therapy are important considerations in developing a treatment plan. Nonsurgical treatment of navic ... | 2011 | 21882161 |
| functional characterization of eul47 in productive replication, morphogenesis and infectivity of equine herpesvirus 1. | eul47 is a major component of the tegument of equine herpesvirus 1 (ehv-1). to determine its function, we used red/et cloning to delete its gene (gene 13) from ehv-1 strain ab4p inserted into a bacterial artificial chromosome (bac), yielding ab4pattbδ13. we also examined the reverted virus (ab4pattb13r). ab4pattbδ13 replicated in rabbit kidney (rk)-13 cells, indicating that orf13 is dispensable for virus replication in cell culture. its intracellular and extracellular titers were about 10- and 1 ... | 2011 | 22056848 |
| A prospective longitudinal study of naturally infected horses to evaluate the performance characteristics of rapid diagnostic tests for equine influenza virus. | An outbreak of equine influenza (EI) occurred in Australia in 2007. During the laboratory support for this outbreak, real-time reverse transcriptase polymerase chain reaction (qRT-PCR) assays and a blocking enzyme linked immunosorbent assay (bELISA) were used as testing methods to detect infection with the virus. The qRT-PCR and bELISA tests had not been used for EI diagnosis before, so it was not known how soon after infection these tests would yield positive results, or for how long these resu ... | 2011 | 22115969 |
| the in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells. | objectives: to investigate the effects of commonly used antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells (msc) in vitro. materials and methods: bone marrow-derived msc were cultured in media containing gentamicin, amikacin, penicillin, enrofloxacin or ceftiofur at concentrations of 50, 100, 200 and 500 µg/ml. the alamarblue fluorescence assay was used to assess cell viability over 48 h. after 5 days the cells were released and lysed prior ... | 2011 | 21883415 |
| [Effects of high doses of genistein on mammary gland of female rat]. | to evaluate the effects of high doses of genistein on the mammary glands of adult female rats. | 2011 | 22189855 |
| The biology of equine mesenchymal stem cells: phenotypic characterization, cell surface markers and multilineage differentiation. | Mesenchymal stem cells (MSCs) are multipotent stem cells that can give rise to a range of connective tissue cells including osteoblasts, chondrocytes and adipocytes. MSCs have been isolated from humans and a variety of animal species including rodents, dogs, horses and rabbits. There is currently no consensus on how these cells are identified and characterized. This is partly due to the lack of standardized specific cell surface markers for MSCs. The aim of this review is to examine the literatu ... | 2012 | 22201780 |
| ovarian responses in bos indicus heifers treated to synchronise ovulation with intravaginal progesterone releasing devices, oestradiol benzoate, prostaglandin f(2α) and equine chorionic gonadotrophin. | the objectives were: (i) improve understanding of the ovarian responses of bos indicus heifers treated with different ovulation synchronisation protocols, (ii) compare ovarian responses of b. indicus heifers treated with intravaginal progesterone releasing device (iprd)+oestradiol benzoate (odb) versus a conventional prostaglandin f(2α) (pgf(2α)) protocol and (iii) investigate whether reducing the amount of progesterone (p(4)) in the iprd, and treatment with equine chorionic gonadotrophin (ecg) ... | 2011 | 22136725 |
| Surgical therapy of advanced ligature-induced peri-implantitis defects: cone-beam computed tomographic and histological analysis. | To evaluate radiological bone level (RBL) (i.e. cone-beam computed tomography) and histological bone levels (HBL) as well as re-osseointegration [bone-to-implant contact (BIC)] after surgical resective (i.e. implantoplasty) and/or regenerative therapy of advanced ligature-induced peri-implantitis in dogs. | 2011 | 21883358 |
| Views sought on equine trading scheme. | | 2011 | 22102347 |
| Immunological correlates of vaccination and infection for equine herpesvirus type 1. | Equine herpesvirus type I (EHV-1) induces a variety of disease manifestations including respiratory disease, abortions and myeloencephalopathy. Several vaccines are commercially available but could not previously be distinguished by serologic testing from infection with EHV-1 (or the closely related EHV-4). Currently available vaccines are not reliably protective from the severe manifestations of the disease, including fatal myeloencephalopathy. We determined immunological parameters that can di ... | 2011 | 22205656 |
| The Combination of Purified Recombinant Human Platelet-Derived Growth Factor-BB and Equine Particulate Bone Graft for Periodontal Regeneration. | Background: The objective of this study was to evaluate the potential for periodontal regeneration of a critical-sized defect with the application of recombinant human platelet-derived growth factor (rhPDGF-BB) combined with either a particulate equine or a ß-tricalcium phosphate (ß-TCP) matrix. Methods: Critical-sized intrabony two-wall defects were created bilaterally on the distal surface of the 2(nd) premolar and the mesial surface of the 1(st) molar in 9 hounds. Twelve defects received rhP ... | 2011 | 22014175 |
| Phospholipid composition of plasma and erythrocyte membranes in animal species by 31P NMR. | The aim of this study was to provide basal values of phospholipid (PL) composition in different animal species by 31P NMR analysis using detergents. This fast and accurate method allowed a quantitative analysis of PLs without any previous separation. Plasma and erythrocyte membrane PLs were investigated in mammals (pig, cow, horse). Moreover, for the first time, the composition of plasma PLs in avian (chicken and ostrich) was performed by 31P NMR. Significant qualitative and quantitative intersp ... | 2011 | 21881904 |
| comparison of equine tendon- and bone marrow-derived cells cultured on tendon matrix with or without insulin-like growth factor-i supplementation. | objective-to compare in vitro expansion, explant colonization, and matrix synthesis of equine tendon- and bone marrow-derived cells in response to insulin-like growth factor-i (igf-i) supplementation. sample-cells isolated from 7 young adult horses. procedures-tendon- and bone marrow-derived progenitor cells were isolated, evaluated for yield, and cultured on autogenous cell-free tendon matrix for 7 days. samples were analyzed for cell viability and expression of collagen type i, collagen ty ... | 2012 | 22204302 |
| A comparison of antibody responses to commercial equine influenza vaccines following primary vaccination of Thoroughbred weanlings--a randomised blind study. | Many racing authorities, sales companies and equestrian bodies have mandatory vaccination policies for equine influenza (EI). The consequences of lack of vaccine efficacy include clinical disease, disruption to training programmes, the cancellation of equestrian events and the introduction of virus to susceptible populations. The correlation between antibody against the virus haemagglutinin and protection against influenza has been well established. The objective of this study was to compare the ... | 2011 | 21983355 |
| bothrops lanceolatus bites: guidelines for severity assessment and emergent management. | approximately 20-30 declared snakebite cases occurin martinique each year. bothrops lanceolatus, a member of the crotalidae family, is considered to be the only involved snake. b. lanceolatus, commonly named "fer-de-lance", is endemic and only found on this caribbean island. envenomation local features include the presence of fang marks, swelling, pain, bleeding from punctures, and ecchymosis. severe envenomation is associated with multiple systemic thromboses appearing within 48 h of the bite a ... | 2010 | 22069552 |
| Effects of flushing and hormonal treatment on reproductive performance of Iranian Markhoz goats. | Forty-eight Iranian Markhoz goats were allocated to six groups (n = 8) to study the effect of flushing and hormonal treatments on reproductive performance. Treatments were divided into two categories including, hormonal treatments and flushing. The goats in each group were fed the same basal ration and received one of the following treatments: Groups A and B - injection of GnRH and equine chorionic gonadotropin (eCG) respectively; Groups C, D and E - a supplement of barley grain, soybean oil and ... | 2011 | 21967729 |
| evaluation and management of the recumbent adult horse. | evaluation and management of recumbent horses are challenging. familiarity with disorders that can result in recumbency will facilitate more rapid diagnosis and more appropriate formulation of a prognosis. with rapid and appropriate diagnosis, appropriate treatment can be pursued and, with good nursing care, can result in a favorable outcome. | 2011 | 22100043 |
| the effect of sodium fluoride preservative and storage temperature on the stability of cocaine in horse blood, sheep vitreous and deer muscle. | the in vitro stability of cocaine in horse blood, sheep vitreous humour (vh) and homogenised deer muscle is described. the stability of cocaine in horse blood was of interest because many toxicology laboratories utilise horse blood for the preparation of calibration and check standards and the latter are typically stored during routine use. the storage stability of cocaine in human vh and muscle has not been previously reported. in the absence of blank human vh and muscle, cocaine stability unde ... | 2011 | 22185825 |
| ileocolonic aganglionosis in an overo foal. | abstract the american paint horse or pinto (spanish for painted) has two different types within the breed: the overo, which has white patches on a dark coat and the tobiano, which has black patches on a white coat. within the overo type the amount of white may be quite small or a horse may be almost entirely white, but the basic pattern is that the ventral abdomen is spotted white whilst dorsal aspects are dark. the overo is considered to be recessive. | 1994 | 22133156 |
| Relationships between in vivo microdamage and the remarkable regional material and strain heterogeneity of cortical bone of adult deer, elk, sheep and horse calcanei. | Natural loading of the calcanei of deer, elk, sheep and horses produces marked regional differences in prevalent/predominant strain modes: compression in the dorsal cortex, shear in medial-lateral cortices, and tension/shear in the plantar cortex. This consistent non-uniform strain distribution is useful for investigating mechanisms that mediate the development of the remarkable regional material variations of these bones (e.g. collagen orientation, mineralization, remodeling rates and secondary ... | 2011 | 21951210 |
| development and evaluation of a reverse transcription loop-mediated isothermal amplification assay for h3n8 equine influenza virus. | reverse transcription loop-mediated isothermal amplification (rt-lamp) was applied to the detection of equine influenza virus (eiv). because equine influenza is caused currently by eiv of the h3h8 subtype, the rt-lamp primer set was designed to target the hemagglutinin gene of this subtype. the detection limit of the rt-lamp assay was a virus dilution of 10(-5); which was 10(3) times more sensitive than the espline influenza a&b-n test and 10 times more sensitive than a reverse transcription pol ... | 2011 | 21907240 |
| intradermal injections of equine allogeneic umbilical cord-derived mesenchymal stem cells are well tolerated and do not elicit immediate or delayed hypersensitivity reactions. | background aims. the use of allogeneic mesenchymal stem cells (msc) to treat acute equine lesions would greatly expand equine cellular therapy options; however, the safety and antigenicity of these cells have not been well-studied. we hypothesized that equine allogeneic umbilical cord tissue (uct)-derived msc would not elicit acute graft rejection or a delayed-type hypersensitivity response when injected intradermally. methods. six quarterhorse yearlings received 12 intradermal injections (autol ... | 2011 | 21899391 |
| Development of a multiplex assay for the detection of antibodies to Borrelia burgdorferi in horses and its validation using Bayesian and conventional statistical methods. | Lyme disease is a zoonotic, vector-borne disease and occurs in mammals including horses. The disease is induced by infection with spirochetes of the Borrelia burgdorferi sensu lato group. Infection of mammalian hosts requires transmission of spirochetes by infected ticks during tick bites. Lyme disease diagnosis is based on clinical signs, possible exposure to infected ticks, and antibody testing which is traditionally performed by ELISA and Western blotting (WB). This report describes the devel ... | 2011 | 21890217 |
| Ventromedial prefrontal cortex damage does not impair the development and use of common ground in social interaction: Implications for cognitive theory of mind. | During conversation, interactants draw on their shared communicative context and history ("common ground") to help decide what to say next, tailoring utterances based on their knowledge of what the listener knows. The use of common ground draws on an understanding of the thoughts and feelings of others to create and update a model of what is known by the other person, employing cognitive processes such as theory of mind. We tested the hypothesis that the ventromedial prefrontal cortex (vmPFC), a ... | 2011 | 22120006 |
| equine piroplasmosis associated with amblyomma cajennense ticks, texas, usa. | we report an outbreak of equine piroplasmosis in southern texas, usa, in 2009. infection prevalence reached 100% in some areas (292 infected horses). amblyomma cajennense was the predominant tick and experimentally transmitted theileria equi to an uninfected horse. we suggest that transmission by this tick species played a role in this outbreak. | 2011 | 22000367 |
| performance evaluation of the sysmex poch-100iv diff hematology analyzer for analysis of canine, feline, equine, and bovine blood. | the sysmex poch-100iv diff is an impedance hematology analyzer recently introduced for point-of-care use in veterinary practices in europe. | 2011 | 22092369 |
| nictitating membrane resection in the horse: a comparison of long-term outcomes using local vs. general anaesthesia. | neoplasia, for which surgical excision is a frequent treatment, is the most common disease of the equine nictitating membrane. there is little long-term follow-up information available to the practitioner regarding the long-term effects of nictitating membrane excision on ocular health. no information is available to compare recurrence of primary neoplasia of the nictitating membrane after excision with local or general anaesthesia. | 2011 | 22082445 |
| the prevalence and nature of cardiac arrhythmias in horses following general anaesthesia and surgery. | abstract: background: the prevalence and nature of arrhythmias in horses following general anaesthesia and surgery is poorly documented. it has been proposed that horses undergoing emergency surgery for gastrointestinal disorders may be at particular risk of developing arrhythmias. our primary objective was to determine the prevalence and nature of arrhythmias in horses following anaesthesia in a clinical setting and to establish if there is a difference in the prevalence of arrhythmias between ... | 2011 | 22112936 |
| microbiological condition of horse meat prepared at a north american packing plant, and control of the temperatures of product air freighted to europe. | to obtain information about the microbiological quality of horse meat exported from north america, the microbiological conditions of hot or cold boned primal cuts and carcass quarters from horse carcasses processed at a north american packing plant were examined. in addition, temperature histories were obtained from boxes of hot boned meat during cooling, and from horse carcass quarters air freighted to europe. the log mean numbers of aerobes recovered from horse carcasses after dressing were >2 ... | 2005 | 22062989 |
| time budget-, behavioral synchrony- and body score development of a newly released przewalski's horse group equus ferus przewalskii, in the great gobi b strictly protected area in sw mongolia. | the przewalski's horse (equus ferus przewalskii) became extinct in the wild in the 1960s, but survived as a species due to captive breeding. there have been several initiatives to re-introduce the species in central asia, but until now only two projects in mongolia establish free-ranging populations. data on basic ecology and behavior of the species prior to extinction is largely lacking and a good documentation of the re-introduction process is essential. between 13 may and 2 september 2003 we ... | 2007 | 22064904 |
| Resistance to Macrocyclic Lactones. | Resistance to the macrocyclic lactones (MLs) has been confirmed or suspected in many target organisms and is a serious problem in some. For some species, such as parasitic nematodes of small ruminants, ML resistance has become severe enough to threaten effective worm control worm control. Resistance is also a major concern in horse parasites and an emerging problem in cattle. Despite this, we have insufficient understanding of the mechanisms of ML resistance, especially in nematodes. Some insect ... | 2011 | 22039786 |
| Haemolysis induced by a-toxin from Staphylococcus aureus requires P2X receptor activation. | Recently, it was documented that a-haemolysin (HlyA) from Escherichia coli uses erythrocyte P2 receptors cause lysis. This finding was surprising as it appeared firmly established that HlyA-dependent pore formation per se is sufficient for full cell lysis. We discovered that HlyA induced a sequential process of shrinkage and swelling and that the final haemolysis is completely prevented by blockers of P2X receptors and pannexin channels. This finding has potential clinical relevance as it may of ... | 2011 | 21847558 |
| Is a single force plate adequate for stabilographic analysis in horses? | Reasons for performing study: Postural balance can be quantified using stabilographic variables derived from force plate data that describe movements of the horse's centre of pressure (COP) in the horizontal plane. Most force plates are not large enough to accommodate all 4 limbs of a standing horse, so the study was designed to assess whether representative stabilographic data could be collected from the forelimbs or hindlimbs. Objective: To determine whether stabilographic data from either the ... | 2011 | 21880064 |
| Hendra virus infection dynamics in Australian fruit bats. | Hendra virus is a recently emerged zoonotic agent in Australia. Since first described in 1994, the virus has spilled from its wildlife reservoir (pteropid fruit bats, or 'flying foxes') on multiple occasions causing equine and human fatalities. We undertook a three-year longitudinal study to detect virus in the urine of free-living flying foxes (a putative route of excretion) to investigate Hendra virus infection dynamics. Pooled urine samples collected off plastic sheets placed beneath roosting ... | 2011 | 22174865 |
| Femtosecond UV studies of the electronic relaxation processes in Cytochrome c. | We report on an experimental study with UV and visible ultrafast time-gated emission and transient absorption of the early photodynamics of horse heart Cytochrome c in both ferric and ferrous redox states. A clear separation in time and energy of tryptophan and haem emission is observed. Excitation of the haem via resonant energy transfer from the tryptophan residue is observed in the subsequent haem electronic relaxation. Different Trp-haem energy transfer time constants of the ferrous and ferr ... | 2011 | 22004429 |
| investigation of strongyle epg values in horse mares relative to known age, number positive, and level of egg shedding in field studies on 26 farms in central kentucky (2010-2011). | a parasite study was done in 1,300 horse mares on 26 farms in central kentucky over a 5-month period in 2010 and 2011. the mares included 1,114 thoroughbreds (tb) on 24 farms, 64 standardbreds (sb) on 1 farm, and 122 mixed light horse types (mlh) on 1 farm. the objective of this research was to determine strongyle eggs per gram of feces (epg) counts for evaluation by known age, number positive, and level of egg shedding by the mares. this was done to establish strongyle epg profiles for the mare ... | 2011 | 22167377 |
| cell-based therapies for equine joint disease. | joint disease is a major cause of wastage in performance horses. arthritis can be challenging to treat because articular cartilage has little or no capacity for repair, therapeutic options are limited and are largely targeted at ameliorating clinical signs of joint disease. cell-based therapies have potential to overcome the intrinsic constraints to articular cartilage repair. this article focuses on cell-based therapies for treatment of equine joint disease. results from experimental model and ... | 2011 | 21872762 |
| influence of different commercial scaffolds on the in vitro differentiation of human mesenchymal stem cells to nucleus pulposus-like cells. | introduction: cell-based therapies for regeneration of the degenerated intervertebral disc (ivd) are an alternative to current surgical intervention. mesenchymal stem cells (mscs), in combination with a scaffold, might be ideal candidates for regenerating nucleus pulposus (np), the pressure-distributing part of the ivd. while the use of growth factors for mscs differentiation currently receives major attention, in this study we compare the performance of sponge-like matrixes in supporting cell d ... | 2011 | 21863459 |
| in vitro activity of ponazuril against theileria equi. | the equid hemoprotozoan parasite theileria equi is endemic in most regions worldwide. infection of horses is a cause of significant economic loss due to costs associated with disease and restriction of trade with non-endemic nations. the ability of certain drugs such as imidocarb dipropionate to eliminate persistent t. equi infection and transmission risk is controversial. the anti-protozoal agent ponazuril has been used successfully to treat equine sarcosystis neurona and toxoplasma gondii. the ... | 2011 | 22130334 |
| collagen-based biological glue after appleby operation for advanced gastric cancer. | pancreatic fistula is a common complication of distal pancreatectomy; although various surgical procedures have been proposed, no clear advantage is evident for a single technique. we herein report the case of a 38-year-old patient affected by an advanced gastric carcinoma infiltrating the pancreas body, with extensive nodal metastases involving the celiac trunk, who underwent total gastrectomy with lymphadenectomy, distal pancreatectomy and resection en bloc of the celiac trunk (appleby operati ... | 2011 | 22046095 |
| Finite element analysis and physiologic testing of a novel, inset glenoid fixation technique. | HYPOTHESIS: The success of shoulder arthroplasty surgery has been limited by a common complication: glenoid implant loosening. Eccentric loading of the glenoid due to migration of the humeral head is considered to be the major cause of glenoid loosening and is referred to as the rocking-horse phenomenon. Glenoid implant loosening may cause pain, limitation of function, and the need for complicated revision surgery. Our hypothesis was that an inset fixation technique could offer increased fixatio ... | 2011 | 22173268 |