| minim typing--a rapid and low cost mlst based typing tool for klebsiella pneumoniae. | here we report a single nucleotide polymorphism (snp) based genotyping method for klebsiella pneumoniae utilising high-resolution melting (hrm) analysis of fragments within the multilocus sequence typing (mlst) loci. the approach is termed mini-mlst or minim typing and it has previously been applied to streptococcus pyogenes, staphylococcus aureus and enterococcus faecium. six snps were derived from concatenated mlst sequences on the basis of maximisation of the simpsons index of diversity (d). ... | 2012 | 22428067 |
| the rise of the enterococcus: beyond vancomycin resistance. | the genus enterococcus includes some of the most important nosocomial multidrug-resistant organisms, and these pathogens usually affect patients who are debilitated by other, concurrent illnesses and undergoing prolonged hospitalization. this review discusses the factors involved in the changing epidemiology of enterococcal infections, with an emphasis on enterococcus faecium as an emergent and challenging nosocomial problem. the effects of antibiotics on the gut microbiota and on colonization w ... | 2012 | 22421879 |
| wild birds as biological indicators of environmental pollution: antimicrobial resistance patterns of escherichia coli and enterococci isolated from common buzzards (buteo buteo). | a total of 36 escherichia coli and 31 enterococci isolates were recovered from 42 common buzzard faecal samples. the e. coli isolates showed high levels of resistance to streptomycin and tetracycline. the following resistance genes were detected: bla(tem) (20 of 22 ampicillin-resistant isolates), tet(a) and/or tet(b) (16 of 27 tetracycline-resistant isolates), aada1 (eight of 27 streptomycin-resistant isolates), cmla (three of 15 chloramphenicol-resistant isolates), aac(3)-ii with/without aac(3) ... | 2012 | 22403140 |
| removal of patulin from apple juice using inactivated lactic acid bacteria. | apples and apple products are the most notably commodities contaminated with patulin (pat), which cause detrimental effects on human health and economic problems. the primary objective of this study was to investigate the removal of pat contamination from apple juice using 10 different inactivated lactic acid bacteria (lab) strains. | 2012 | 22394257 |
| detection of cc17 enterococcus faecium in dogs and a comparison with human isolates. | enterococcus faecium strains of clonal complex (cc) 17 were isolated from domestic dogs. the strains were more prevalent in infectious isolates than in colonized isolates, suggesting that strains of the cc17 lineage may have an advantage in causing infections in dogs. the pulsed field gel electrophoresis patterns of some dog and human isolates were over 90% similar. however, antimicrobial resistance patterns and virulence factors were not identical, which might reflect different use of antimicro ... | 2012 | 22372965 |
| comparative analysis of the first complete enterococcus faecium genome. | vancomycin-resistant enterococci (vre) are one of the leading causes of nosocomial infections in health care facilities around the globe. in particular, infections caused by vancomycin-resistant enterococcus faecium are becoming increasingly common. comparative and functional genomic studies of e. faecium isolates have so far been limited owing to the lack of a fully assembled e. faecium genome sequence. here we address this issue and report the complete 3.0-mb genome sequence of the multilocus ... | 2012 | 22366422 |
| hospital and community ampicillin-resistant enterococcus faecium are evolutionarily closely linked but have diversified through niche adaptation. | ampicillin-resistant enterococcus faecium (are) has emerged as a nosocomial pathogen. here, we quantified are carriage in different community sources and determined genetic relatedness with hospital are. | 2012 | 22363425 |
| newly isolated lactic acid bacteria with probiotic features for potential application in food industry. | five newly isolated lactic acid bacteria were identified as weissella cibaria, enterococcus faecium, and three different strains of lactobacillus plantarum by 16s rrna sequencing. essential probiotic requirements of these isolates such as tolerance to phenol, low ph, high sodium chloride, and bile salt concentration were checked. efficiency in adherence to mucin and hydrophobicity of the bacterial cell were also evaluated by in vitro studies. antimicrobial activities against some pathogens were ... | 2012 | 22350936 |
| enterococcus faecium ncimb 10415 does not protect interleukin-10 knock-out mice from chronic gut inflammation. | enterococcus faecium ncimb 10415 reduces diarrhoea incidence and duration in animals and human study subjects. we tested whether the strain is also capable of reducing chronic gut inflammation and aimed to identify mechanisms that are involved in possible probiotic effects. to identify health-promoting mechanisms of the strain, we used interleukin-10-deficient mice that spontaneously develop gut inflammation and fed these mice a diet containing ncimb 10415 for 3, 8 and 24 weeks, respectively. co ... | 2012 | 22348908 |
| hematological: low all-cause mortality and low occurrence of antimicrobial resistance in hematological patients with bacteremia receiving no antibacterial prophylaxis: a single-center study. | bacteremia is a major cause of morbidity and mortality in patients with hematological malignancies. | 2012 | 22335785 |
| infectious disease survey of mus musculus from pet stores in new york city. | most mice used in research are purchased devoid of specific pathogens. experimental studies required us to evaluate the profile of infective agents harbored in mice sold as pets or food for captive reptiles. anecdotal reports regarding disease in these mice abound, but there are few published reports on disease prevalence. purchasers are unaware of the potential zoonotic or adventitious infections carried by these mice. this survey investigated the prevalence of ectoparasites, endoparasites, and ... | 2012 | 22330866 |
| genetic diversity among vre isolates from swedish broilers with the coincidental finding of transferrable decreased susceptibility to narasin. | in this study, the molecular diversity among clones of vancomycin resistant enterococcus faecium with vana gene (vre) is investigated. the aims were to better understand why one clone is predominant in swedish broiler production and to better assess the potential for zoonotic gene transfer from the different clones. | 2012 | 22324455 |
| lysozyme facilitates adherence of enterococcus faecium to host cells and induction of necrotic cell death. | the prevalence of infections with enterococci is increasing worldwide. however, little is known about the mechanisms which enable these opportunistic pathogens to cause infections of their host. here we demonstrate that enterococcus faecium in the presence of lysozyme induces necrosis in human and mouse cells after 4 h indicated by disrupted cellular membranes of epithelial (hela), myeloid (u937, j774a.1) and lymphoid (jurkat j16, thymocytes), but not intestinal epithelial cells (caco-2, cmt-93) ... | 2012 | 22306275 |
| efficacy of multiple metals against copper-resistant bacterial strains. | the antibacterial efficacy of zeolites containing copper (cu) or silver (ag) ions or a combination was assessed against several reported copper-resistant (cu(r)) bacterial strains. | 2012 | 22277101 |
| effect of enterocin 4231 in slovak fermented salami púchov after its experimental inoculation with listeria innocua li1. | enteroccocci occur and may compete well in fermented sausages and enterococcus faecium represents that species of the lactic acid bacteria which can be found in the fermented sausages. the representatives of this species can produce bacteriocins with predominant anti-listerial effect. therefore, the effect of enterocin (ent) 4231 produced by enterococcus faecium ccm 4231 strain with probiotic properties was tested in a dry fermented salami púchov (slovak product) experimentally inoculated with l ... | 2012 | 22230924 |
| factors influencing the occurence of nosocomial bloodstream infections observed in thoracic and cardiosurgical postoperative care units. | the aim of this study was to analyse the epidemiology and aetiology of laboratoryconfirmed bloodstream infections (lc-bsi) and central line-associated bloodstream infections (clabsi) after pulmonary and coronary surgery, in postoperative intensive care units in 2009. | 2014 | 23801507 |
| the effect of a silage inoculant on silage quality, aerobic stability, and meat production on farm scale. | the effect of inoculation on nutrient content, fermentation, aerobic stability, and beef cattle performance for whole-plant corn silage treated with a commercial product (blend of homo- and heterofermentative lactic acid bacteria, bsm, blend of enterococcus faecium, lactobacillus plantarum, and lactobacillus brevis, dsm numbers 3530, 19457, and 23231, resp.), was compared to a control treatment with no silage additives (ct). the material had a dm of 323 g/kg, crude protein, and water-soluble car ... | 2012 | 23738122 |
| effect of ingestion of soy yogurt on intestinal parameters of rats fed on a beef-based animal diet. | the aim of this study was to investigate whether the ingestion of soy yogurt fermented with enterococcus faecium crl 183 would modify the intestinal count of enterococci, fecal ph and ammonia content in rats fed on a diet containing red meat. the rats were placed in 4 groups: for 60 days, group i was given a standard casein-based rodent feed and groups ii-iv, the beef-based feed. from day 30, groups iii-iv also received the following products: iii) soy yogurt; iv) suspension of e. faecium crl 18 ... | 2011 | 24031747 |
| enterococcus faecium coisolated with lactobacillus species can mimic vancomycin-resistant enterococci. | | 2011 | 22957117 |
| selection of starter cultures for idli batter fermentation and their effect on quality of idlis. | idli batter samples were prepared using lactic starter cultures like pediococcus pentosaceus (pp), enterococcus faecium mtcc 5153 (ef), ent. faecium (ib2 ef-ib2), individually, along with the yeast culture, candida versatilis (cv). idli batter prepared using ef and ef-ib2 cultures gave better results, when evaluated for the rise in batter volume (80 ml), level of co2 production (23.8%), titratable acidity 2.4-3.5% (lactic acid) and ph 4.3-4.4. storage stability of batter made with selected start ... | 2010 | 23572685 |
| synthesis and biological evaluation of muraymycin analogues active against anti-drug-resistant bacteria. | muraymycin analogues with a lipophilic substituent were synthesized using an ugi four-component assemblage. this approach provides ready access to a range of analogues simply by altering the aldehyde component. the impact of the lipophilic substituent on the antibacterial activity was very large, and analogues 7b-e and 8b-e exhibited good activity against a range of gram-positive bacterial pathogens including methicillin-resistant staphylococcus aureus and vancomycin-resistant enterococcus faeci ... | 2010 | 24900205 |
| characterization of a heat stable anti-listerial bacteriocin produced by vancomycin sensitive enterococcus faecium isolated from idli batter. | lactic acid bacteria (lab) are known to produce various types of bacteriocins, ribosomally synthesized polypeptides, which have antibacterial spectrum against many food borne pathogens. listeria monocytogenes, a pathogenic bacterium, is of particular concern to the food industry because of its ability to grow even at refrigeration temperatures and its tolerance to preservative agents. some of the bacteriocins of lab are known to have anti-listerial property. in the present study, the bacteriocin ... | 2010 | 23100837 |
| purification and characterization of enterocin fh 99 produced by a faecal isolate enterococcus faecium fh 99. | enterococcus faecium fh 99 was isolated from human faeces and selected because of its broad spectrum of inhibitory activity against several gram-positive foodborne spoilage and pathogenic bacteria. ent. faecium fh 99 accumulates enterocin in large number in early stationary phase of the growth. the enterocin fh 99 was stable over a wide ph range (2-10) and recovered activity even after treatment at high temperatures (10 min at 100°c). the enterocin was subjected to different purification techniq ... | 2010 | 23100821 |
| encapsulation of lactobacillus plantarum 423 and its bacteriocin in nanofibers. | plantaricin 423, produced by lactobacillus plantarum 423, was encapsulated in nanofibers that were produced by the electrospinning of 18% (w/v) polyethylene oxide (200 000 da). the average diameter of the nanofibers was 288 nm. plantaricin 423 activity decreased from 51 200 au/ml to 25 600 au/ml and from 204 800 au/ml to 51 200 au/ml after electrospinning, as determined against lactobacillus sakei dsm 20017 and enterococcus faecium hklhs, respectively. cells of l. plantarum 423 encapsulated in n ... | 2010 | 26780900 |
| influence of an enterococcus faecium probiotic on the development of peyer's patches b cells in piglets. | to study the interactions between a probiotic bacterium and the host's immune system, we undertook a feeding trial with enterococcus faecium sf68 (ncimb 10415). starting at an age of 1 day, piglets received a daily oral dose of the probiotic bacteria. immune cells were isolated from the blood and the distal continuous peyer's patch (pp) of the piglets. while the percentage of b cells in the distal continuous pp was not influenced by the probiotic treatment, an elevated expression of cd1 on peyer ... | 2009 | 26967794 |
| apparent absorption of methionine and 2-hydroxy-4-methylthiobutanoic acid from gastrointestinal tract of conventional and gnotobiotic pigs. | the effect of commensal microbiota and feeding corn or wheat/barley-based diets on the apparent gastrointestinal absorption of dl-methionine (met) and 2-hydroxy-4-methylthiobutanoic acid (mha-fa) was studied in conventional (n = 32) and gnotobiotic pigs (n = 24). conventional pigs (con) were vaginally delivered and sow-reared until weaning at 14 days of age. gnotobiotic pigs were derived by caesarian section and reared in hepa (high efficiency particulate air)-filtered isolator units with ad lib ... | 2009 | 22444932 |
| successful control of vancomycin-resistant enterococcus faecium outbreak in a neurosurgical unit at non-endemic region. | vancomycin-resistant enterococci (vre) have emerged in many parts of the world, but have only been reported sporadically in hong kong. we report an outbreak of vancomycin-resistant enterococcus faecium (vrefm) in a neurosurgical unit at a tertiary teaching hospital between 3 march and 3 april 2009 in hong kong. during the outbreak investigation, clinical samples from 193 (91.5%) of 211 patients who had stayed in the neurosurgical unit and 506 environmental samples were screened for vrefm. beside ... | 2009 | 22460290 |
| effect of lactulose on growth performance and intestinal morphology of pre-ruminant calves using a milk replacer containing enterococcus faecium. | the synthetic disaccharide lactulose is known to improve the intestinal microflora by stimulating the growth of selected probiotic bacteria in the gut. in our experiment the effects of lactulose in combination with the probiotic bacteria enterococcus faecium on growth performance and morphology of the bovine intestine were examined. calves aged 39 ± 2 days were randomised to three feeding groups (no. = 14 each group): control (l0), fed milk replacer (mr) containing e. faecium; a lactulose group ... | 2007 | 22444334 |
| improvement of peroxyl radical scavenging bioassay based on bactericidal action of tert-butyl peroxyl radical. | an improved bioassay for measurement of peroxyl radical scavenging activity(1,2)) is described. the modifications included the use of (1) enterococcus faecium strain s, (2) 25% dimethyl sulfoxide, (3) l-ascorbic acid for the termination of the bactericidal reaction, and (4) the concentration of antioxidants that gives 75% of the log (colony forming unit/ml) of the control reaction (without methemoglobin or tert-butyl hydroperoxide), for the expression of antioxidant activity. | 1999 | 27393264 |
| anti-mutagenic and immuno-stimulatory properties of lactic acid bacteria. | statistically significant antigenotoxic activity was exerted by six of nine strains of lactic acid bacteria tested (lactobacillus delbrueckii subsp. bulgaricus, staphylococcus carnosus, streptococcus thermophilus, l. rhamnosus, enterococcus faecium and en. faecalis) against nitrovin and 2-aminofluorene in salmonella typhimurium ta100 and ta97. the mutagenic activity of both mutagens was substantially decreased by viable bacteria; cells heated to 100°c for 15 min were ineffective. in vitro, en. f ... | 1995 | 24414651 |
| bacillus fermentation of soybeans. | kinema fermentations of indian and canadian no. 1 soybeans by bacillus sp. dk-w1 and by mixed cultures of bacillus sp. dk-w1 and enterococcus faecium dk-c1 were essentially identical. the viable cell count of bacillus increased from an initial 10(5) to 10(10) c.f.u./g wet wt after 48 h incubation at 37°c. the ph of the fermentation dropped from an initial 6.9 to about 6.4 after 8 h and then rose to 8.6 after 32 h, with a coincident increase in proteolytic activity and ammonia concentration. the ... | 1993 | 24420029 |
| nutritional requirements in multiple auxotrophic lactic acid bacteria: genetic lesions affecting amino acid biosynthetic pathways in lactococcus lactis, enterococcus faecium, and pediococcus acidilactici. | in a study of genetic lesions responsible for amino acid requirements in multiple auxotrophic lactic acid bacteria, a systematic attempt was made to isolate mutants that could synthesize each of the amino acids required by the parental strains of lactococcus lactis, enterococcus faecium, and pediococcus acidilactici. after treatment with appropriate mutagens or, in some cases, spontaneously, such mutants could indeed be obtained with respect to many but not all essential amino acids. successful ... | 1992 | 27280812 |
| antimicrobial activity of lactobacilli and streptococci. | of nine strains of lactic acid bacteria commonly used as starter cultures for the dalry industry and ensiling, six (lactobacillus bulgaricus, l. casei, l. acidophilus ch=5, l. plantarum, streptococcus latis and strep. taecium) had antibiotic activity. gram-positive bacteria were more sensitive than gram-negative bacteria to the antibiotics. the most sensitive strain of staphylococcus aureus was used as a target micro-organism for the characterization of the antimicrobial substance. the cultures ... | 1991 | 24425193 |
| non-beta-lactamase-producing penicillin-resistant enterococcus faecium in a clinical setting. | six clinical isolates of enterococcus faecium highly resistant to penicillin are reported. these strains did not produce beta-lactamase and no plasmid dna could be detected. it is postulated that the mechanism of resistance is one or more chromosomally mediated alterations of penicillin-binding proteins. | 1990 | 22553444 |
| the ecology of the streptococci. | all species of streptococci are divided into several groups according to the ecological niches they occupy. members of the lactic acid group are found only in the plant environment and the dairy. members of the pyogenic group and the buccal and intestinal residents of the subthermophilic group are found in intimate association only with homeothermic hosts. members of the virulent pyogenic group, such asstreptococcus pyogenes, s. equi, ands. infrequens, are restricted to single hosts-the human, t ... | 1982 | 24226053 |
| coliforms and enterococci isolated from the intestinal tract of conventional mice. | coliforms and enterococci were isolated from the intestinal tract of infant (12-day-old) and adult (6-to 8-week-old) conventional mice. eighty coliform isolates and eighty enterococcal strains were grouped according to their ability to ferment or hydrolyze various substrates. sixty-one of the coliform isolates were identified asescherichia coli. the remaining 19 strains were similar toe. coli, but did not produceβ-galactosidase. the enterococci belonged to two species:streptococcus faecium ands. ... | 1979 | 24232296 |
| probiotic therapy reduces inflammation and improves intestinal morphology in rats with induced oral mucositis. | the aim of the present study was to evaluate the effect of systemic administration of probiotics (prob) on the progression of experimentally induced oral and intestinal mucositis in rats immunosuppressed by chemotherapy (5-fluorouracil: 5-fu). twenty-four rats were divided into the following groups (n=6): gc (control), gprob, g5fu and g5-fu/prob. groups gprob and g5-fu/prob received 1 g of probiotic incorporated into each 100 g of feed (bacillus subtilis, bifidobacterium bifidum, enterococcus fa ... | 2017 | 28678976 |
| solid-state fermentation of corn-soybean meal mixed feed with bacillus subtilis and enterococcus faecium for degrading antinutritional factors and enhancing nutritional value. | corn and soybean meal (sbm) are two of the most common feed ingredients used in pig feeds. however, a variety of antinutritional factors (anfs) present in corn and sbm can interfere with the bioavailability of nutrients and have negative health effects on the pigs. in the present study, two-stage fermentation using bacillus subtilis followed by enterococcus faecium was carried out to degrade anfs and improve the nutritional quality of corn and sbm mixed feed. furthermore, the microbial compositi ... | 2017 | 28603613 |
| synthesis and structural characterization of silver nanoparticles stabilized with 3-mercapto-1-propansulfonate and 1-thioglucose mixed thiols for antibacterial applications. | the synthesis, characterization and assessment of the antibacterial properties of hydrophilic silver nanoparticles (agnps) were investigated with the aim to probe their suitability for innovative applications in the field of nanobiotechnology. first, silver nanoparticles were synthetized and functionalized with two capping agents, namely 3-mercapto-1-propansulfonate (3mps) and 1-β-thio-d-glucose (tg). the investigation of the structural and electronic properties of the nano-systems was carried o ... | 2016 | 28774148 |
| vancomycin-resistant enterococci with vana and vanb genes in australian gulls. | this study is revealing the possible dissemination of vancomycin-resistant enterococci (vre) from humans into the wildlife. we studied silver gulls (chroicocephalus novaehollandiae) in australia as potential carriers and reservoirs of vre with acquired vancomycin resistance. in new south wales (australia), we have found two multi-resistant isolates belonging to enterococcus faecium (sequence type 341, vanb genotype) and enterococcus dispar (vana genotype). based on our knowledge, this is the fir ... | 2017 | 28464539 |
| safety evaluation of enterocin producer enterococcus sp. strains isolated from traditional turkish cheeses. | the purpose of this study was to determine the antimicrobial activity and occurrence of bacteriocin structural genes in enterococcus spp. isolated from different cheeses and also investigate some of their virulence factors. enterococcus strains were isolated from 33 different cheeses. enterococcus faecium (6 strains) and enterococcus faecalis (5 strains) enterocin-producing strains were identified by 16s rdna analyses. structural genes enta, entb, entp and entx were detected in some isolates. mu ... | 2017 | 28735309 |
| inactivation of viruses and bacteria on strawberries using a levulinic acid plus sodium dodecyl sulfate based sanitizer, taking sensorial and chemical food safety aspects into account. | the efficacy of levulinic acid (lva) in combination with sodium dodecyl sulfate (sds) in removal of foodborne viruses, enteric bacterial pathogens and their surrogates on fresh strawberries was investigated. inoculated strawberries were treated with potable water, sodium hypochlorite solution (50ppm), 0.5% lva plus 0.5% sds solution, and 5% lva plus 2% sds solution respectively for 2min, followed by spray-rinsing with potable water. water washing removed at least 1.0-log of the tested viral and ... | 2017 | 28668727 |
| impact of thistle rennet from carlina acanthifolia all. subsp. acanthifolia on bacterial diversity and dynamics of a specialty italian raw ewes' milk cheese. | caciofiore della sibilla is an italian specialty soft cheese manufactured with sopravissana raw ewes' milk and thistle rennet prepared with young fresh leaves and stems of carlina acanthifolia all. subsp. acanthifolia, according to an ancient tradition deeply rooted in the territory of origin (mountainous hinterland of the marche region, central italy). in this study, the impact of thistle rennet on the bacterial dynamics and diversity of caciofiore della sibilla cheese was investigated by apply ... | 2017 | 28558331 |
| genetic characterization of vana-enterococcus faecium isolates from wild red-legged partridges in portugal. | vancomycin-resistant enterococci (vre) have been detected in wild animals representing a public health concern. the red-legged partridge (alectoris rufa) is a common game bird and its meat is consumed in several countries, including portugal. three hundred five fecal samples of red-legged partridge from the north of portugal were screened for vre. samples were cultured on slanetz-bartley agar supplemented with vancomycin (4 mg/l) and six vana-enterococcus faecium were recovered. isolates were te ... | 2017 | 28504889 |
| comparison of a new matrix-assisted laser desorption/ionization time-of-flight mass spectrometry platform, asta microidsys, with bruker biotyper for species identification. | matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, with its accuracy and speed, is widely used for bacterial identification. the asta microidsys system (asta, korea) was recently developed for species identification. we compared its performance with that of bruker biotyper (bruker daltonics, germany). microbes were recovered from sputum, urine, and pus samples from patients admitted to a tertiary care hospital in korea from january to april 2016. matrix solution (α-cya ... | 2017 | 28840993 |
| [distribution and drug resistance of pathogens at hematology department of jiangsu province from 2014 to 2015: results from a multicenter, retrospective study]. | objective: to describe the distribution and drug resistance of pathogens at hematology department of jiangsu province from 2014 to 2015 to provide reference for empirical anti-infection treatment. methods: pathogens were from hematology department of 26 tertiary hospitals in jiangsu province from 2014 to 2015. antimicrobial susceptibility testing was carried out according to a unified protocol using kirby-bauer method or agar dilution method. collection of drug susceptibility results and corresp ... | 2017 | 28810329 |
| antimicrobial efficacy and synergy of metal ions against enterococcus faecium, klebsiella pneumoniae and acinetobacter baumannii in planktonic and biofilm phenotypes. | the effects of metal ion solutions (silver, copper, platinum, gold and palladium) were determined individually and in combination against enterococcus faecium, acinetobacter baumannii and klebsiella pneumoniae. platinum, gold and palladium showed the greatest antimicrobial efficacy in zone of inhibition (zoi) assays. when tested in combinations using zoi assays, gold/platinum, gold/palladium and platinum/palladium were indicative of synergy. microbial inhibitory concentration demonstrated platin ... | 2017 | 28724953 |
| antimicrobial susceptibility among gram-positive and gram-negative organisms collected from the latin american region between 2004 and 2015 as part of the tigecycline evaluation and surveillance trial. | the in vitro activity of tigecycline and comparator agents was evaluated against gram-positive and gram-negative isolates collected in latin american centers between 2004 and 2015 as part of the tigecycline evaluation and surveillance trial (t.e.s.t.) global surveillance study. | 2017 | 28701170 |
| titanium surfaces immobilized with the major antimicrobial fragment fk-16 of human cathelicidin ll-37 are potent against multiple antibiotic-resistant bacteria. | infections on implanted medical devices are a challenging problem, especially when bacteria form difficult-to-treat biofilms. antimicrobial peptides are considered to be a solution due to their potency against antibiotic-resistant superbugs. previously, the authors' laboratory demonstrated the prevention of staphylococcal biofilm formation in an animal catheter model by injecting merecidin (formerly known as 17biphe2), a peptide engineered based on the only human cathelicidin. this study documen ... | 2017 | 28675109 |
| nonribosomal peptide synthetase biosynthetic clusters of eskape pathogens. | covering: up to 2017.natural products are important secondary metabolites produced by bacterial and fungal species that play important roles in cellular growth and signaling, nutrient acquisition, intra- and interspecies communication, and virulence. a subset of natural products is produced by nonribosomal peptide synthetases (nrpss), a family of large, modular enzymes that function in an assembly line fashion. because of the pharmaceutical activity of many nrps products, much effort has gone in ... | 2017 | 28642945 |
| identification of 1-((2,4-dichlorophenethyl)amino)-3-phenoxypropan-2-ol, a novel antibacterial compound active against persisters of pseudomonas aeruginosa. | antibiotics typically fail to completely eradicate a bacterial population, leaving a small fraction of transiently antibiotic-tolerant persister cells intact. persisters are therefore seen to be a major cause of treatment failure and greatly contribute to the recalcitrant nature of chronic infections. the current study focused on pseudomonas aeruginosa, a gram-negative pathogen belonging to the notorious eskape group of pathogens (enterococcus faecium, staphylococcus aureus, klebsiella pneumonia ... | 2017 | 28630188 |
| patterns of multi-drug resistant bacteria at first culture from patients admitted to a third level university hospital in calabria from 2011 to 2014: implications for empirical therapy and infection control. | surveillance of antimicrobial drug resistance is fundamental to guide empirical treatment. however, the european antimicrobial resistance surveillance network provides a general picture, which might not be applicable to clinical settings that are excluded from this survey. we evaluated resistance patterns of eskape isolates over a four-year period in a third level university hospital in the province of catanzaro (southern italy). in this retrospective study, we evaluated the frequency of eskape ... | 2017 | 28603227 |
| bacteria from animals as a pool of antimicrobial resistance genes. | antimicrobial agents are used in both veterinary and human medicine. the intensive use of antimicrobials in animals may promote the fixation of antimicrobial resistance genes in bacteria, which may be zoonotic or capable to transfer these genes to human-adapted pathogens or to human gut microbiota via direct contact, food or the environment. this review summarizes the current knowledge of the use of antimicrobial agents in animal health and explores the role of bacteria from animals as a pool of ... | 2017 | 28587316 |
| celecoxib enhances the efficacy of low-dose antibiotic treatment against polymicrobial sepsis in mice and clinical isolates of eskape pathogens. | treatment of multidrug resistant bacterial infections has been a great challenge globally. previous studies including our study have highlighted the use of celecoxib, a non-steroidal anti-inflammatory drug in combination with antibiotic has decreased the minimal inhibitory concentration to limit staphylococcus aureus infection. however, the efficacy of this combinatorial treatment against various pathogenic bacteria is not determined. therefore, we have evaluated the potential use of celecoxib i ... | 2017 | 28533769 |
| the use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence. | this review sets out to evaluate the current evidence on the impact of inappropriate therapy on bloodstream infections (bsi) and associated mortality. based on the premise that better prescribing practices should result in better patient outcomes, bsi mortality may be a useful metric to evaluate antimicrobial stewardship (ams) interventions. a systematic search was performed in key medical databases to identify papers published in english between 2005 and 2015 that examined the association betwe ... | 2017 | 28458799 |
| recovery of metallo-tolerant and antibiotic resistant psychrophilic bacteria from siachen glacier, pakistan. | cultureable bacterial diversity of previously unexplored siachen glacier, pakistan, was studied. out of 50 isolates 33 (66%) were gram negative and 17 (34%) gram positive. about half of the isolates were pigment producers and were able to grow at 4-37°c. 16s rrna gene sequences revealed gram negative bacteria dominated by proteobacteria (especially γ-proteobacteria and β-proteobacteria) and flavobacteria. the genus pseudomonas (51.51%, 17) was dominant among γ- proteobacteria. β-proteobacteria c ... | 2017 | 28746396 |
| clinical and microbiological characteristics of pantoea agglomerans infection in children. | pantoea agglomerans is an environmental gram-negative bacterium that rarely is responsible for the infections in humans but it is often a causative factor of a number of occupational diseases. this study evaluated the clinical and microbiological characteristics and pathogenicity of p. agglomerans in children. we retrospectively reviewed microbiological test results for all children (1 month old to 18 years old) who were admitted to our pediatric hospital between january 2000 to june 2015 and ha ... | 2017 | 28780309 |
| diversity and probiotic potential of lactic acid bacteria isolated from horreh, a traditional iranian fermented food. | the aim of this study was to evaluate the probiotic potential of lactic acid bacteria (lab) strains isolated from horreh. some probiotic properties, e.g., resistance to acid, bile tolerance, antibacterial activity, and antibiotic susceptibility, were investigated. a total of 140 gram-positive and catalase-negative isolates from horreh were subjected to identification and grouping by cultural methods and the 16s rrna sequencing. the new isolates were identified to be lactobacillus (fermentum, pla ... | 2017 | 28527125 |
| self assembled snowball-like hybrid nanostructures comprising viburnum opulus l. extract and metal ions for antimicrobial and catalytic applications. | herein, we report the production of novel organic-inorganic nanobio-catalytic and antimicrobial agents called "nanosnowball" (nsbs) with a rational design and elucidate the increase in the catalytic and antimicrobial activities. the nsbs resemble to guelder rose were formed of the extract of viburnum opulus (vo) as the organic component and copper (ii) ions (cu(2+)) as the inorganic component. the effects of the vo extract and cu(2+) concentrations on the morphology of nsbs were systematically e ... | 2017 | 28465062 |
| in vitro antimicrobial activity screening of xylaria hypoxylon. | fungi have a potential of using both as nutritive and medicinal food stuff. because of containing several therapeutic agents, they are reported to be used for hundreds of years to treat several diseases caused by bacteria, fungi, viruses and parasites. the aim of this study is to determine the in vitro antimicrobial activity of xylaria hypoxylon, which were collected from yomra, trabzon, turkey. | 2016 | 28852719 |
| chemical sterilization of allograft dermal tissues. | common terminal sterilization methods are known to alter the natural structure and properties of soft tissues. one approach to providing safe grafts with preserved biological properties is the combination of a validated chemical sterilization process followed by an aseptic packaging process. this combination of processes is an accepted method for production of sterile healthcare products as described in ansi/aami st67:2011. this article describes the validation of the peracetic acid and ethanol- ... | 2017 | 28799106 |
| reactivity toward bifidobacterium longum and enterococcus hirae demonstrate robust cd8(+) t cell response and better prognosis in hbv-related hepatocellular carcinoma. | recent studies suggest that several bacterial species are involved in tumor immunosurveillance and antitumor immunity. the role of bacteria in immune responses in hbv-related hepatocellular carcinoma (hcc) patients is still unknown. in this study, we examined the bacteria-reactive cd8(+) t cell response in patients with hbv-related hcc. we found that circulating cd8(+) t cells from healthy individuals demonstrated minimal or zero specificity toward a series of commensals and bacteria previously ... | 2017 | 28694023 |
| what the eyes don't see, the heart does grieve over. | a 71 year old peruvian woman presented with blurry vision and bilateral eye pain and had evidence of bilateral endophthalmitis on eye examination. her past medical history was notable for multiple abdominal surgeries within the preceding months, including an incarcerated inguinal hernia repair which required an ileostomy placement, and cholecystitis requiring cholecystostomy tube placement. over her multiple long hospitalizations, she developed bacteremia and fungemia on several occasions, with ... | 2017 | 28414678 |
| frogs host faecal bacteria typically associated with humans. | tree frogs commonly access drinking water tanks; this may have human health implications. although amphibians might not be expected to host mammalian faecal indicator bacteria (fib), it is possible that they may have human fib on their skin after exposure to human waste. we collected faeces and skin wash from green tree frogs (litoria caerulea) from a natural environment, a suburban site, and a suburban site near a creek occasionally contaminated with sewage effluent. we used molecular technique ... | 2017 | 28414918 |
| effect of a probiotic beverage consumption (enterococcus faecium crl 183 and bifidobacterium longum atcc 15707) in rats with chemically induced colitis. | some probiotic strains have the potential to assist in relieving the symptoms of inflammatory bowel disease. the impact of daily ingestion of a soy-based product fermented by enterococcus faecium crl 183 and lactobacillus helveticus 416 with the addition of bifidobacterium longum atcc 15707 on chemically induced colitis has been investigated thereof within a period of 30 days. | 2017 | 28437455 |
| cooperating commensals restore colonization resistance to vancomycin-resistant enterococcus faecium. | antibiotic-mediated microbiota destruction and the consequent loss of colonization resistance can result in intestinal domination with vancomycin-resistant enterococcus (vre), leading to bloodstream infection in hospitalized patients. clearance of vre remains a challenging goal that, if achieved, would reduce systemic vre infections and patient-to-patient transmission. although obligate anaerobic commensal bacteria have been associated with colonization resistance to vre, the specific bacterial ... | 2017 | 28494240 |
| vancomycin-resistant enterococci with vana gene in treated municipal wastewater and their association with human hospital strains. | vancomycin-resistant enterococci (vre) are pathogens of increasing medical importance. in brno, czech republic, we collected 37 samples from the effluent of a wastewater treatment plant (wwtp), 21 surface swabs from hospital settings, and 59 fecal samples from hospitalized patients and staff. moreover, we collected 284 gull cloacal swabs from the colony situated 35km downstream the wwtp. samples were cultured selectively. enterococci were identified using maldi-tof ms, phenotypically tested for ... | 2017 | 28763660 |
| exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance. | commensal intestinal bacteria can prevent pathogenic infection; however, limited knowledge of the mechanisms by which individual bacterial species contribute to pathogen resistance has restricted their potential for therapeutic application. here, we examined how colonization of mice with a human commensal enterococcus faecium protects against enteric infections. we show that e. faecium improves host intestinal epithelial defense programs to limit salmonella enterica serotype typhimurium pathogen ... | 2016 | 28580440 |
| inhibition of clostridium difficile in mice using a mixture of potential probiotic strains enterococcus faecalis nm815, e. faecalis nm915, and e. faecium nm1015: novel candidates to control c. difficile infection (cdi). | this study is aimed at the isolation, identification, and characterization of potential probiotic strains capable of inhibiting clostridium difficile in vitro and in vivo. twenty isolates were isolated from infant fecal samples and screened against c. difficile using their cell-free supernatant. only three isolates showed maximum inhibition from 56.05 to 60.60%, thus they were characterized for probiotic properties and safety. the results obtained approved their tolerance to the gastrointestinal ... | 2017 | 28497217 |
| avi-lution® supplemented at 1.0 or 2.0 g/kg in feed improves the growth performance of broiler chickens during challenge with bacitracin-resistant clostridium perfringens. | avi-lution® is a defined, patented, synbiotic product containing saccharomyces cerevisiae, enterococcus faecium, and bacillus spp. broiler chickens (n = 1,250) were experimentally treated as uninoculated controls (ucon), inoculated controls (icon) with clostridium perfringens, or inoculated and treated with bacitracin methylene disalicylate (bmd) at 55 mg/kg as an infected/treated control or avi-lution® at 1.0 (avl1) or 2.0 (avl2) g/kg in feed for 42 d. each treatment was applied to 10 replicate ... | 2017 | 28431095 |
| bloodstream infections caused by enterococcus spp: a 10-year retrospective analysis at a tertiary hospital in china. | in order to discover the risk factors for 30-day mortality in bloodstream infections (bsi) caused by enterococcus spp. strains, we explored the clinical and therapeutic profile of patients with enterococcus spp. bsi and the characteristics of this condition. a total of 64 patients with bsi caused by enterococcus spp. who were treated in our hospital between 2006 and 2015 were included in the study. the clinical features of patients, microbiology, and 30-day mortality were collected from the elec ... | 2017 | 28397040 |
| diversity of antagonistic bacteria isolated from medicinal plant peganum harmala l. | the antimicrobial activity of plant extract of peganum harmala, a medicinal plant has been studied already. however, knowledge about bacterial diversity associated with different parts of host plant antagonistic to different human pathogenic bacteria is limited. in this study, bacteria were isolated from root, leaf and fruit of plant. among 188 bacterial isolates isolated from different parts of the plant only 24 were found to be active against different pathogenic bacteria i.e. escherichia coli ... | 2017 | 28855824 |
| genomic insights into the pathogenicity and environmental adaptability of enterococcus hirae r17 isolated from pork offered for retail sale. | genetic information about enterococcus hirae is limited, a feature that has compromised our understanding of these clinically challenging bacteria. in this study, comparative analysis was performed of e. hirae r17, a daptomycin-resistant strain isolated from pork purchased from a retail market in beijing, china, and three other enterococcal genomes (enterococcus faecium do, enterococcus faecalis v583, and e. hirae atcc(™) 9790). some 1,412 genes were identified that represented the core genome t ... | 2017 | 28799224 |
| revisiting nitrofurantoin for vancomycin resistant enterococci. | enterococcal infection has emerged as a major therapeutic challenge. emergence of high level aminoglycoside resistance (hlar) and vancomycin-resistant enterococcus (vre) has further limited the drug therapy in enterococcal infections. however, nitrofuratoin being an old drug reported to have less resistance in comparison to the other classes of antimicrobial agents. | 2017 | 28764160 |
| telavancin activity in vitro tested against a worldwide collection of gram-positive clinical isolates (2014). | telavancin activity was measured against gram-positive pathogens collected worldwide during 2014 using the revised broth microdilution testing method. the results were compared with previous reports. | 2017 | 28735051 |
| in vitro activity of telavancin against clinically important gram-positive pathogens from 69 u.s. medical centers (2015): potency analysis by u.s. census divisions. | a total of 8,072 gram-positive isolates collected from 69 medical centers among all 9 u.s. census divisions during the 2015 sentry antimicrobial surveillance program were included. telavancin had minimal inhibitory concentration (mic)50 and mic90 values of 0.03/0.06 μg/ml, respectively, against methicillin-susceptible (mssa) and methicillin-resistant staphylococcus aureus (mrsa). similar activity was also observed among coagulase-negative staphylococci (mic50/90, 0.03/0.06 μg/ml; 100.0% inhibite ... | 2017 | 28727951 |
| incidence, clinical characteristics, and outcomes of nosocomial enterococcus spp. bloodstream infections in a tertiary-care hospital in beijing, china: a four-year retrospective study. | enterococcus spp. are the common cause of nosocomial bloodstream infections (bsis) with high morbidity and mortality. the purpose of this study was to characterize the incidence, clinical and microbiological features, and mortality of nosocomial enterococcal bsis at a large chinese tertiary-care hospital in beijing, china. | 2017 | 28680588 |
| carriage of multidrug resistant enterococcus faecium and enterococcus faecalis among apparently healthy humans. | enterococci are indigenous flora of the gastro-intestinal tracts of animals and humans. recently, interest in two major species, e. faecium and e. faecalis, has heightened because of their ability to cause serious infections and their intrinsic resistance to antimicrobials. this study was aimed at determining the prevalence of e. faecium and e. faecalis in human faecal samples and evaluating the susceptibility of the isolates to antibiotics. | 2017 | 28670644 |
| urinary tract infections after kidney transplantation: a risk factor analysis of 417 patients. | background the aim of this study was to evaluate the number of urinary tract infections (uti) that occur after kidney transplantation (kt) and to identify possible risk factors for development of a uti. material and methods we retrospectively analyzed all kts performed between january 2012 and december 2013 in the erasmus university medical center, rotterdam. uti was scored if: (1) a patient had a urine culture with no more than 2 species of microorganisms, (2) at least 1 of which was a bacteriu ... | 2017 | 28663538 |
| phtβ-promoted mobilization of non-conjugative resistance plasmids from enterococcus faecium to enterococcus faecalis. | to analyse the recombination events associated with conjugal mobilization of two multiresistance plasmids, prum17i48 and plag (formerly named pdo1-like), from enterococcus faecium 17i48 to enterococcus faecalis jh2-2. | 2017 | 28645197 |
| bactericidal activity and synergy studies of peptide ap-cect7121 against multi-resistant bacteria isolated from human and animal soft tissue infections. | ap-cect7121 is an antimicrobial peptide, produced by enterococcus faecalis cect7121, with bactericidal activity against gram-positive bacteria. the aim of this study was to evaluate the bactericidal activity of ap-cect7121, alone and with gentamicin, against multi-resistant bacteria isolated from human and animals with soft tissue infections. during the period 2014-2015, bacterial strains producing human and animal soft tissue infections were studied. samples from patients attended at a general ... | 2017 | 28573492 |
| antimicrobial resistance status of enterococcus from australian cattle populations at slaughter. | antimicrobial agents are used in cattle production systems for the prevention and control of bacterial associated diseases. a consequence of their use is the potential development of antimicrobial resistance (amr). enterococcus faecium and enterococcus faecalis that are resistant to antimicrobials are of increased concern to public health officials throughout the world as they may compromise the ability of various treatment regimens to control disease and infection in human medicine. australia i ... | 2017 | 28542602 |
| emergence of vana enterococcus faecium in denmark, 2005-15. | to describe the changing epidemiology of vancomycin-resistant enterococcus faecium and enterococcus faecalis in clinical samples in denmark 2005-15 according to species and van type, and, furthermore, to investigate the genetic relatedness of the clinical e. faecium isolates from 2015. | 2017 | 28541565 |
| occurrence of enterococcus faecalis and enterococcus faecium in various clinical infections: detection of their drug resistance and virulence determinants. | the aim of this study was to characterize virulence determinants and antibiotic resistance profiles in enterococci obtained from various clinical sources in the northwest of iran. a total of 160 enterococcal clinical isolates from various wards of university teaching hospitals were collected and specified by biochemical test, from september 2014 to july 2015. identification of enterococci was confirmed by multiplex pcr in the genus and species level. antibiotic resistance properties and virulenc ... | 2017 | 28525287 |
| occurrence of ampicillin-resistant enterococcus faecium carrying esp gene in pet animals: an upcoming threat for pet lovers. | this study was carried out to investigate oral colonisation by enterococcus faecalis and enterococcus faecium in pet dogs and cats, with special reference to antibiotic resistance. | 2017 | 28499907 |
| five-year summary of in vitro activity and resistance mechanisms of linezolid against clinically important gram-positive cocci in the united states from the leader surveillance program (2011 to 2015). | this report describes linezolid susceptibility testing results for 6,741 gram-positive pathogens from 60 u.s. sites collected during 2015 for the leader program. in addition, the report summarizes linezolid in vitro activity, resistance mechanisms, and molecular typing obtained for 2011 to 2015. during 2015, linezolid showed potent activity in testing against staphylococcus aureus, inhibiting >99.9% of 3,031 isolates at ≤2 µg/ml. similarly, linezolid showed coverage against 99.2% of coagulase-ne ... | 2017 | 28483950 |
| [effects of application of vancomycin in the early stage of patients with extremely severe burn]. | objective: to evaluate the effects of application of vancomycin in the early stage of patients with extremely severe burn, in order to provide reference to drug for anti-infection treatment in the early stage of patients with extremely severe burn. methods: data of 15 patients of kunshan explosion on august 2nd, 2014, admitted to the department of intensive care in our hospital were retrospectively analyzed. the clinical efficacy of continuously intravenous dripping of vancomycin (combined with ... | 2017 | 28427133 |
| antibiotic resistant airborne bacteria and their multidrug resistance pattern at university teaching referral hospital in south ethiopia. | hospitals provide a reservoir of microorganisms, many of which are multi-resistant to antibiotics. emergence of multi-drug resistant strains in a hospital environment, particularly in developing countries is an increasing problem to infection treatment. this study aims at assessing antibiotic resistant airborne bacterial isolates. | 2017 | 28403894 |
| meso-dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity. | thirty-three meso-dihydroguaiaretic acid (meso-dga) derivatives bearing esters, ethers, and amino-ethers were synthesized. all derivatives were tested against twelve drug-resistant clinical isolates of gram-positive and gram-negative bacteria, including sensitive (h37rv) and multidrug-resistant mycobacterium tuberculosis strains. among the tested compounds, four esters (7, 11, 13, and 17), one ether (23), and three amino-ethers (30, 31, and 33) exhibited moderate activity against methicillin-res ... | 2017 | 28844400 |
| characterization of microbiota in arapaima gigas intestine and isolation of potential probiotic bacteria. | the aim of this study was to determine the intestinal microbiota of pirarucu (a. gigas) in different growth stages (adult and fingerlings), and to isolate and identify potential probiotic bacteria. | 2017 | 28833934 |
| reversible inactivation of a peptidoglycan transpeptidase by a β-lactam antibiotic mediated by β-lactam-ring recyclization in the enzyme active site. | β-lactam antibiotics act as suicide substrates of transpeptidases responsible for the last cross-linking step of peptidoglycan synthesis in the bacterial cell wall. nucleophilic attack of the β-lactam carbonyl by the catalytic residue (ser or cys) of transpeptidases results in the opening of the β-lactam ring and in the formation of a stable acyl-enzyme. the acylation reaction is considered as irreversible due to the strain of the β-lactam ring. in contradiction with this widely accepted but poo ... | 2017 | 28831100 |
| effectiveness of automated ultraviolet-c light for decontamination of textiles inoculated with enterococcus faecium. | healthcare textiles are increasingly recognized as potential vehicles for transmission of hospital-acquired infections. we tested the ability of an automated ultraviolet-c (uv-c) room disinfection device (tru-d(®) smart uvc) to decontaminate textiles inoculated with enterococcus faecium in a clinical setting. contaminated polycotton (50/50 polyester/cotton) swatches were distributed to predefined locations in a ward room and exposed to uvc light. uvc-decontamination reduced e. faecium counts by ... | 2017 | 28827192 |
| pathobactyper: a web server for pathogenic bacteria identification and molecular genotyping. | with the decline in the cost of whole-genome sequencing because of the introduction of next-generation sequencing (ngs) techniques, many public health and clinical laboratories have started to use bacterial whole genomes for epidemiological surveillance and clinical investigation. for epidemiological and clinical purposes in this "ngs era," whole-genome-scale single nucleotide polymorphism (wgsnp) analysis for genotyping is considered suitable. in this paper, we present an online service, pathob ... | 2017 | 28824598 |
| complete genome sequence of a novel, virulent ahjdlikevirus bacteriophage that infects enterococcus faecium. | a novel virulent bacteriophage named vb_efap_ime199 that specifically infects enterococcus faecium was isolated and characterized. its optimal multiplicity of infection was 0.01, and it had a 30 minute outbreak period. high-throughput sequencing revealed that the phage has a dsdna genome of 18,838 bp with 22 open reading frames. the genome has very low homology to all other bacteriophage sequences in the genbank database. run-off sequencing experiments confirmed that vb_efap_ime199 has short inv ... | 2017 | 28812171 |
| vancomycin-resistant enterococcus faecium st17 outbreak in a neonatal unit. | | 2017 | 28807390 |
| comparative pharmacodynamics of single-dose oritavancin and daily high-dose daptomycin regimens against vancomycin-resistant enterococcus faecium isolates in an in vitro pk/pd model of infection. | there are limited therapeutic options to treat infections caused by vancomycin-resistant enterococcus faecium (vrefm). the lipoglycopeptide oritavancin exhibits in vitro activity against this pathogen although its utility against infections caused by vrefm has not been established clinically. in this study, the pharmacodynamic activity of free-drug levels associated with 12 mg/kg/day of daptomycin and a single 1200 mg dose of oritavancin were determined against three vana vrefm isolates in an in ... | 2017 | 28784674 |
| inhibitory substances production by lactobacillus plantarum st16pa cultured in hydrolyzed cheese whey supplemented with soybean flour and their antimicrobial efficiency as biopreservatives on fresh chicken meat. | cheese whey, the main byproduct of the dairy industry, is one of the most worrisome types of industrial waste, not only because of its abundant annual global production but also because it is a notable source of environmental pollution. however, cheese whey can serve as a raw material for the production of biocomposites. in this context, in this study, we assayed the production of a bacteriocin-like inhibitory substance (blis) and lactate by culturing lactobacillus plantarum st16pa in hydrolyzed ... | 2017 | 28784542 |
| treatment of vancomycin-resistant enterococci: focus on daptomycin. | vancomycin-resistant enterococci (vre) infections are problematic due to limited availability of anti-vre agents and their potential for adverse effects and drug interactions. this review focuses on the role of daptomycin in treating vre infections by summarizing key points of relevant clinical studies. | 2017 | 28779348 |
| clonal dissemination of vancomycin-resistant enterococcus faecium st412 in a brazilian region. | vancomycin-resistant enterococcus faecium (vrefm) has emerged as an important global nosocomial pathogen, and this trend is associated with the spread of high-risk clones. here, we determined the genetic and phenotypic features of 93 vrefm isolates that were obtained from patients in 13 hospitals in vitória, espírito santo, brazil, during 2012-2013. all the isolates were vancomycin-resistant and harbored the vana gene. only 6 (6.5%) of the vrefm isolates showed the ability to form biofilm. the 9 ... | 2017 | 28759747 |
| first description in europe of emergence of enterococcus faecium st117, carrying both vana/vanb genes, isolated in greece. | an enterococcus faecium, carrying both vana/vanb genes was recovered from a patient with bacteraemia, treated in a greek hospital. since this is the first description in europe of e. faecium, carrying both vana/vanb genes, the isolate was further studied. | 2017 | 28754459 |